Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbitter taste receptor activity

TAS2R14 TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

2.73e-19279811GO:0033038
GeneOntologyMolecularFunctiontaste receptor activity

TAS2R14 TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

3.95e-18339811GO:0008527
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC12A6 CACNA1F SLC36A4 SLC2A7 SLC22A11 SLC19A2 FLVCR2 OTOP3 SLC13A2 SLC1A6 SLC22A7 SLC39A8 ABCB1 ABCB4 ITPR3 SLC22A9 P2RX7 NALCN SLC15A1 SLC15A2 SLC26A7 SCN1A SCN4A SCN7A SCN8A SCN10A SLC47A1 ATP13A3 SLC25A29 SLC41A1 ATP2B1 SLC7A10 ATP2B4

5.94e-1711809833GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SLC12A6 CACNA1F SLC36A4 SLC2A7 SLC22A11 SLC19A2 FLVCR2 OTOP3 SLC13A2 SLC1A6 SLC22A7 SLC39A8 ABCB1 ABCB4 ITPR3 SLC22A9 P2RX7 NALCN SLC15A1 SLC15A2 SLC26A7 SCN1A SCN4A SCN7A SCN8A SCN10A TMEM30A SLC47A1 ATP13A3 SLC25A29 SLC41A1 ATP2B1 SLC7A10 ATP2B4

1.01e-1612899834GO:0005215
GeneOntologyMolecularFunctionG protein-coupled receptor activity

VN1R2 GALR1 OR1S1 FPR1 OR4C45 ADGRV1 OR51E2 GHRHR OR2B11 CELSR1 TAS2R14 OR2A12 GPR142 TAS2R33 TAS2R36 MTNR1A OPN5 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50 GPR176 CX3CR1

9.59e-158849827GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

VN1R2 GALR1 OR1S1 FPR1 OR4C45 ADGRV1 PLXNB2 OR51E2 GHRHR OR2B11 CELSR1 TAS2R14 OR2A12 P2RX7 GPR142 TAS2R33 TAS2R36 SCN7A MTNR1A OPN5 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50 GPR176 CX3CR1

9.91e-1313539830GO:0004888
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC12A6 CACNA1F OTOP3 SLC13A2 SLC1A6 SLC39A8 ITPR3 P2RX7 NALCN SLC15A1 SLC15A2 SCN1A SCN4A SCN7A SCN8A SCN10A SLC47A1 ATP13A3 SLC41A1 ATP2B1 ATP2B4

7.66e-126649821GO:0008324
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC12A6 SLC36A4 SLC22A11 SLC13A2 SLC1A6 SLC22A7 SLC39A8 ABCB1 ABCB4 SLC22A9 SLC15A1 SLC15A2 SLC26A7 SLC47A1 ATP13A3 SLC41A1 ATP2B1 ATP2B4

1.65e-114779818GO:0022804
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC12A6 CACNA1F OTOP3 SLC13A2 SLC1A6 SLC39A8 ITPR3 P2RX7 NALCN SLC15A1 SLC15A2 SLC26A7 SCN1A SCN4A SCN7A SCN8A SCN10A SLC47A1 ATP13A3 SLC41A1 ATP2B1 ATP2B4

2.89e-117939822GO:0015075
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC12A6 CACNA1F SLC22A11 OTOP3 SLC13A2 SLC1A6 SLC39A8 ITPR3 NALCN SLC15A1 SLC15A2 SLC26A7 SCN1A SCN4A SCN7A SCN8A SCN10A SLC47A1 SLC41A1 ATP2B1 ATP2B4

9.00e-117589821GO:0015318
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC12A6 CACNA1F OTOP3 SLC13A2 SLC1A6 SLC39A8 ITPR3 NALCN SLC15A1 SLC15A2 SCN1A SCN4A SCN7A SCN8A SCN10A SLC47A1 SLC41A1 ATP2B1 ATP2B4

1.81e-106279819GO:0022890
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC36A4 SLC22A11 SLC19A2 SLC13A2 SLC1A6 SLC22A7 SLC39A8 ABCB1 SLC22A9 SLC26A7 SLC47A1 SLC25A29 SLC7A10

1.98e-092939813GO:0008514
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC12A6 SLC36A4 SLC22A11 SLC13A2 SLC1A6 SLC22A7 SLC39A8 SLC22A9 SLC15A1 SLC15A2 SLC26A7 SLC47A1 SLC41A1

2.24e-092969813GO:0015291
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

NALCN SCN1A SCN4A SCN7A SCN8A SCN10A

2.55e-0926986GO:0005248
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC36A4 SLC19A2 SLC13A2 SLC1A6 SLC22A7 ABCB1 SLC22A9 SLC26A7 SLC47A1 SLC25A29 SLC7A10

5.80e-092079811GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC36A4 SLC19A2 SLC13A2 SLC1A6 SLC22A7 ABCB1 SLC22A9 SLC26A7 SLC47A1 SLC25A29 SLC7A10

6.10e-092089811GO:0005342
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC12A6 CACNA1F SLC13A2 SLC1A6 SLC39A8 ITPR3 NALCN SCN1A SCN4A SCN7A SCN8A SCN10A SLC41A1 ATP2B1 ATP2B4

7.99e-094659815GO:0046873
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC12A6 SLC13A2 SLC1A6 SLC39A8 SLC15A1 SLC15A2 SLC26A7 SLC47A1 ATP13A3 SLC41A1 ATP2B1 ATP2B4

2.83e-083019812GO:0022853
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC13A2 SLC1A6 NALCN SCN1A SCN4A SCN7A SCN8A SCN10A SLC41A1

1.64e-07171989GO:0015081
GeneOntologyMolecularFunctionsodium channel activity

NALCN SCN1A SCN4A SCN7A SCN8A SCN10A

2.03e-0752986GO:0005272
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC36A4 SLC19A2 SLC47A1 ATP13A3 SLC25A29 SLC7A10

3.33e-0683986GO:0015101
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1F OTOP3 ITPR3 P2RX7 NALCN SCN1A SCN4A SCN7A SCN8A SCN10A

7.20e-063439810GO:0005261
GeneOntologyMolecularFunctionsymporter activity

SLC12A6 SLC36A4 SLC13A2 SLC1A6 SLC39A8 SLC15A1 SLC15A2

9.17e-06150987GO:0015293
GeneOntologyMolecularFunctionchannel activity

SLC12A6 CACNA1F OTOP3 ITPR3 P2RX7 NALCN SLC26A7 SCN1A SCN4A SCN7A SCN8A SCN10A

1.00e-055259812GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SLC12A6 CACNA1F OTOP3 ITPR3 P2RX7 NALCN SLC26A7 SCN1A SCN4A SCN7A SCN8A SCN10A

1.02e-055269812GO:0022803
GeneOntologyMolecularFunctiondicarboxylic acid transmembrane transporter activity

SLC13A2 SLC1A6 SLC22A7 SLC26A7

1.55e-0531984GO:0005310
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1F OTOP3 ITPR3 P2RX7 NALCN SLC26A7 SCN1A SCN4A SCN7A SCN8A SCN10A

1.56e-054599811GO:0005216
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC36A4 SLC1A6 SLC47A1 SLC25A29 SLC7A10

2.59e-0571985GO:0015179
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC12A6 SLC13A2 SLC1A6 SLC39A8 SLC15A1 SLC15A2

2.66e-05119986GO:0015294
GeneOntologyMolecularFunctionamide transmembrane transporter activity

SLC19A2 SLC15A1 SLC15A2 SLC47A1

5.29e-0542984GO:0042887
GeneOntologyMolecularFunctionceramide floppase activity

ABCB1 ABCB4

7.13e-053982GO:0099038
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLC22A11 SLC22A7 SLC22A9

8.87e-0518983GO:0015347
GeneOntologyMolecularFunctionputrescine transmembrane transporter activity

SLC47A1 ATP13A3

1.42e-044982GO:0015489
GeneOntologyMolecularFunctionpeptide:proton symporter activity

SLC15A1 SLC15A2

1.42e-044982GO:0015333
GeneOntologyMolecularFunctionsphingolipid floppase activity

ABCB1 ABCB4

1.42e-044982GO:0046623
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC36A4 SLC1A6 SLC47A1 SLC25A29 SLC7A10

1.68e-04105985GO:0015171
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCB1 ABCB4 ATP13A3 ATP2B1 ATP2B4

2.01e-04109985GO:0042626
GeneOntologyMolecularFunctiondipeptide transmembrane transporter activity

SLC15A1 SLC15A2

2.36e-045982GO:0071916
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCB1 ABCB4 TMEM30A

3.44e-0428983GO:0140326
GeneOntologyMolecularFunctionalpha-ketoglutarate transmembrane transporter activity

SLC13A2 SLC22A7

3.53e-046982GO:0015139
GeneOntologyMolecularFunctionlipid transporter activity

SLC22A11 SLC22A7 ABCB1 ABCB4 SLC22A9 TMEM30A

4.12e-04196986GO:0005319
GeneOntologyMolecularFunctionthiamine transmembrane transporter activity

SLC19A2 SLC47A1

4.93e-047982GO:0015234
GeneOntologyMolecularFunctionphosphatidylcholine floppase activity

ABCB1 ABCB4

6.55e-048982GO:0090554
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP13A3 ATP2B1 ATP2B4

7.28e-0436983GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP13A3 ATP2B1 ATP2B4

7.28e-0436983GO:0015662
GeneOntologyMolecularFunctiontripeptide transmembrane transporter activity

SLC15A1 SLC15A2

8.39e-049982GO:0042937
GeneOntologyMolecularFunctionpeptide transmembrane transporter activity

SLC15A1 SLC15A2

8.39e-049982GO:1904680
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC36A4 SLC1A6 SLC7A10

1.07e-0341983GO:0015175
GeneOntologyMolecularFunctionpolyamine transmembrane transporter activity

SLC47A1 ATP13A3

1.27e-0311982GO:0015203
GeneOntologyMolecularFunctionP-type calcium transporter activity

ATP2B1 ATP2B4

1.27e-0311982GO:0005388
GeneOntologyMolecularFunctionABC-type transporter activity

ABCB1 ABCB4 ATP13A3

1.79e-0349983GO:0140359
GeneOntologyMolecularFunctionL-arginine transmembrane transporter activity

SLC47A1 SLC25A29

1.80e-0313982GO:0061459
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCB1 ABCB4 ATP13A3 ATP2B1 ATP2B4

1.85e-03178985GO:0015399
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCB1 ABCB4 TMEM30A

2.01e-0351983GO:0140303
GeneOntologyMolecularFunctionazole transmembrane transporter activity

SLC19A2 SLC47A1

2.09e-0314982GO:1901474
GeneOntologyMolecularFunctionprostaglandin transmembrane transporter activity

SLC22A11 SLC22A7

2.09e-0314982GO:0015132
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN8A

2.09e-0314982GO:0031402
GeneOntologyMolecularFunctionC4-dicarboxylate transmembrane transporter activity

SLC13A2 SLC1A6

2.40e-0315982GO:0015556
GeneOntologyMolecularFunctionicosanoid transmembrane transporter activity

SLC22A11 SLC22A7

2.40e-0315982GO:0071714
GeneOntologyMolecularFunctionoligopeptide transmembrane transporter activity

SLC15A1 SLC15A2

2.74e-0316982GO:0035673
GeneOntologyMolecularFunctionfloppase activity

ABCB1 ABCB4

2.74e-0316982GO:0140328
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

SCN1A SCN10A

3.09e-0317982GO:0099508
GeneOntologyMolecularFunctionflippase activity

ABCB1 TMEM30A

3.09e-0317982GO:0140327
GeneOntologyMolecularFunctionsulfur compound transmembrane transporter activity

SLC19A2 SLC26A7 SLC47A1

3.36e-0361983GO:1901682
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP13A3 ATP2B1 ATP2B4

3.52e-0362983GO:0019829
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

GALR1 FPR1 GHRHR CX3CR1

4.19e-03133984GO:0008528
GeneOntologyMolecularFunctionbasic amino acid transmembrane transporter activity

SLC47A1 SLC25A29

4.28e-0320982GO:0015174
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

ABCB1 ABCB4

4.28e-0320982GO:0008525
GeneOntologyMolecularFunctionsphingolipid transporter activity

ABCB1 ABCB4

4.28e-0320982GO:0046624
GeneOntologyMolecularFunctionantiporter activity

SLC22A11 SLC26A7 SLC47A1 SLC41A1

4.78e-03138984GO:0015297
GeneOntologyMolecularFunctionpeptide receptor activity

GALR1 FPR1 GHRHR CX3CR1

5.03e-03140984GO:0001653
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

SLC22A11 SLC22A7 SLC22A9

5.56e-0373983GO:0170055
GeneOntologyMolecularFunctionphospholipid transporter activity

ABCB1 ABCB4 TMEM30A

5.78e-0374983GO:0005548
GeneOntologyMolecularFunctiongated channel activity

CACNA1F ITPR3 P2RX7 SCN1A SCN7A SCN10A

6.08e-03334986GO:0022836
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1F ITPR3 ATP2B1 ATP2B4

6.55e-03151984GO:0015085
GeneOntologyMolecularFunctionsolute:proton symporter activity

SLC15A1 SLC15A2

6.65e-0325982GO:0015295
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN8A

7.18e-0326982GO:0031420
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC39A8 SLC26A7

1.07e-0232982GO:0015106
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC22A11 SLC26A7

1.07e-0232982GO:0005452
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCB1 SLC47A1

1.21e-0234982GO:0042910
GeneOntologyBiologicalProcesssensory perception of bitter taste

ITPR3 TAS2R14 TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

4.54e-18489912GO:0050913
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of bitter taste

TAS2R14 TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

1.18e-16449911GO:0001580
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of taste

TAS2R14 TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

5.63e-16509911GO:0050912
GeneOntologyBiologicalProcesssensory perception of taste

ITPR3 TAS2R14 TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

6.35e-16709912GO:0050909
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

VN1R2 GALR1 OR1S1 FPR1 OR4C45 ADGRV1 ADCY8 ITPR3 OR51E2 GHRHR OR2B11 CELSR1 TAS2R14 OR2A12 GPR142 TAS2R33 TAS2R36 MTNR1A OPN5 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50 ATP2B4 GPR176 CX3CR1

1.28e-1213959930GO:0007186
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

CACNA1F OR1S1 OR4C45 ADGRV1 OR51E2 OR2B11 TAS2R14 OR2A12 TAS2R33 TAS2R36 SCN1A SCN10A TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

3.99e-125829920GO:0050906
GeneOntologyBiologicalProcessdetection of stimulus

CACNA1F OR1S1 OR4C45 ADGRV1 OR51E2 OR2B11 TAS2R14 OR2A12 TAS2R33 TAS2R36 SCN1A SCN10A OPN5 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

2.48e-117229921GO:0051606
GeneOntologyBiologicalProcesssensory perception

VN1R2 CACNA1F OR1S1 OR4C45 ADGRV1 ITPR3 OR51E2 OR2B11 TAS2R14 OR2A12 P2RX7 TAS2R33 TAS2R36 SCN1A SCN8A SCN10A OPN5 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

2.69e-1110729925GO:0007600
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

VN1R2 OR1S1 OR4C45 ITPR3 OR51E2 OR2B11 TAS2R14 OR2A12 TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

1.10e-105479918GO:0007606
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC12A6 CACNA1F SLC22A11 FLVCR2 OTOP3 SLC13A2 SLC1A6 SLC22A7 SLC39A8 ABCB1 ITPR3 SLC22A9 P2RX7 NALCN SLC15A1 SLC15A2 SLC26A7 SCN1A SCN4A SCN7A SCN8A SCN10A SLC47A1 ATP13A3 SLC41A1 ATP2B1 ATP2B4

1.76e-1013749927GO:0006811
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR1S1 OR4C45 OR51E2 OR2B11 TAS2R14 OR2A12 TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

1.29e-094859916GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR1S1 OR4C45 OR51E2 OR2B11 TAS2R14 OR2A12 TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

3.89e-095249916GO:0009593
GeneOntologyBiologicalProcesscarboxylic acid transport

SLC36A4 SLC22A11 SLC19A2 SLC13A2 SLC1A6 SLC22A7 ABCB1 ABCB4 SLC22A9 P2RX7 SLC26A7 SLC47A1 SLC25A29 SLC7A10

9.88e-094109914GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

SLC36A4 SLC22A11 SLC19A2 SLC13A2 SLC1A6 SLC22A7 ABCB1 ABCB4 SLC22A9 P2RX7 SLC26A7 SLC47A1 SLC25A29 SLC7A10

1.05e-084129914GO:0015849
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC12A6 CACNA1F OTOP3 SLC13A2 SLC39A8 ABCB1 ITPR3 P2RX7 NALCN SLC15A1 SLC15A2 SLC26A7 SCN1A SCN4A SCN7A SCN8A SCN10A SLC47A1 ATP13A3 SLC41A1 ATP2B1 ATP2B4

1.14e-0811159922GO:0034220
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC12A6 CACNA1F OTOP3 SLC13A2 SLC39A8 ITPR3 P2RX7 NALCN SLC15A1 SLC15A2 SCN1A SCN4A SCN7A SCN8A SCN10A SLC47A1 ATP13A3 SLC41A1 ATP2B1 ATP2B4

1.78e-089429920GO:0098655
GeneOntologyBiologicalProcessorganic anion transport

SLC36A4 SLC22A11 SLC19A2 SLC13A2 SLC1A6 SLC22A7 SLC39A8 ABCB1 ABCB4 SLC22A9 P2RX7 SLC26A7 SLC47A1 SLC25A29 SLC7A10

2.34e-085159915GO:0015711
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC12A6 CACNA1F OTOP3 SLC13A2 SLC39A8 ITPR3 P2RX7 NALCN SLC15A1 SLC15A2 SLC26A7 SCN1A SCN4A SCN7A SCN8A SCN10A SLC47A1 SLC41A1 ATP2B1 ATP2B4

6.30e-0810179920GO:0098660
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC12A6 CACNA1F OTOP3 SLC13A2 SLC39A8 ITPR3 P2RX7 NALCN SLC15A1 SLC15A2 SCN1A SCN4A SCN7A SCN8A SCN10A SLC47A1 SLC41A1 ATP2B1 ATP2B4

6.85e-089229919GO:0098662
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC36A4 SLC13A2 SLC1A6 ABCB1 SLC22A9 SLC26A7 SLC47A1 SLC25A29 SLC7A10

9.08e-08163999GO:1905039
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC12A6 CACNA1F FLVCR2 OTOP3 SLC13A2 SLC39A8 ITPR3 P2RX7 NALCN SLC15A1 SLC15A2 SCN1A SCN4A SCN7A SCN8A SCN10A SLC47A1 ATP13A3 SLC41A1 ATP2B1 ATP2B4

1.08e-0711579921GO:0006812
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC36A4 SLC13A2 SLC1A6 ABCB1 SLC22A9 SLC26A7 SLC47A1 SLC25A29 SLC7A10

1.12e-07167999GO:1903825
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC13A2 NALCN SCN1A SCN4A SCN7A SCN8A SCN10A SLC41A1 ATP2B4

7.17e-07208999GO:0035725
GeneOntologyBiologicalProcesssodium ion transport

SLC13A2 P2RX7 NALCN SCN1A SCN4A SCN7A SCN8A SCN10A SLC41A1 ATP2B4

8.27e-072759910GO:0006814
GeneOntologyBiologicalProcessimport across plasma membrane

SLC12A6 CACNA1F SLC36A4 SLC1A6 SLC39A8 SLC15A1 SLC15A2 SLC47A1 ATP2B4

1.65e-06230999GO:0098739
GeneOntologyBiologicalProcessorganic cation transport

SLC36A4 SLC19A2 SCN4A SLC47A1 ATP13A3 SLC25A29 SLC7A10

6.37e-06145997GO:0015695
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN1A SCN4A SCN7A SCN8A SCN10A

1.20e-0562995GO:0086002
GeneOntologyBiologicalProcessneuronal action potential

P2RX7 SCN1A SCN4A SCN8A SCN10A

1.30e-0563995GO:0019228
GeneOntologyBiologicalProcessxenobiotic transport

ABCB1 ABCB4 SLC15A2 TMEM30A SLC47A1

1.40e-0564995GO:0042908
GeneOntologyBiologicalProcessmetal ion transport

SLC12A6 CACNA1F FLVCR2 SLC13A2 SLC39A8 ITPR3 P2RX7 NALCN SCN1A SCN4A SCN7A SCN8A SCN10A SLC41A1 ATP2B1 ATP2B4

2.12e-0510009916GO:0030001
GeneOntologyBiologicalProcesstripeptide import across plasma membrane

SLC15A1 SLC15A2

2.28e-052992GO:0140207
GeneOntologyBiologicalProcessdicarboxylic acid transport

SLC19A2 SLC13A2 SLC1A6 SLC22A7 P2RX7 SLC26A7

2.47e-05120996GO:0006835
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN1A SCN4A SCN8A SCN10A

2.61e-0536994GO:0086010
GeneOntologyBiologicalProcessamino acid transport

SLC36A4 SLC1A6 P2RX7 SLC15A1 SLC47A1 SLC25A29 SLC7A10

4.33e-05195997GO:0006865
GeneOntologyBiologicalProcessazole transmembrane transport

SLC19A2 SLC47A1 SLC25A29

4.68e-0515993GO:0045117
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN1A SCN4A SCN7A SCN8A SCN10A

6.23e-0587995GO:0086001
GeneOntologyBiologicalProcessL-alpha-amino acid transmembrane transport

SLC36A4 SLC1A6 SLC47A1 SLC25A29 SLC7A10

6.23e-0587995GO:1902475
GeneOntologyBiologicalProcessceramide translocation

ABCB1 ABCB4

6.82e-053992GO:0099040
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

GALR1 FPR1 ADCY8 OR51E2 GHRHR MTNR1A ATP2B4 GPR176

7.13e-05286998GO:0007188
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN1A SCN4A SCN7A SCN8A SCN10A

8.56e-0593995GO:0086003
GeneOntologyBiologicalProcessxenobiotic transmembrane transport

ABCB4 TMEM30A SLC47A1

9.83e-0519993GO:0006855
GeneOntologyBiologicalProcesspositive regulation of cytosolic calcium ion concentration

CD52 GALR1 FPR1 ADCY8 ITPR3 P2RX7 CX3CR1

1.04e-04224997GO:0007204
GeneOntologyBiologicalProcesscalcium ion export

ATP2B1 ATP2B4

1.36e-044992GO:1901660
GeneOntologyBiologicalProcessputrescine transport

SLC47A1 ATP13A3

1.36e-044992GO:0015847
GeneOntologyBiologicalProcessphospholipid translocation

ABCB1 ABCB4 P2RX7 TMEM30A

1.41e-0455994GO:0045332
GeneOntologyBiologicalProcessL-amino acid transport

SLC36A4 SLC1A6 SLC47A1 SLC25A29 SLC7A10

1.73e-04108995GO:0015807
GeneOntologyBiologicalProcessamide transport

SLC19A2 PFKM ADCY8 ABCB1 ABCB4 GHRHR SLC15A1 SLC15A2 MTNR1A

1.90e-04420999GO:0042886
GeneOntologyBiologicalProcessinorganic ion homeostasis

SLC12A6 CACNA1F ADCY8 SLC39A8 ITPR3 P2RX7 SCN7A ATP13A3 SLC41A1 ATP2B1 ATP2B4

1.96e-046229911GO:0098771
GeneOntologyBiologicalProcesslipid translocation

ABCB1 ABCB4 P2RX7 TMEM30A

1.98e-0460994GO:0034204
GeneOntologyBiologicalProcesstransmission of nerve impulse

P2RX7 SCN1A SCN4A SCN8A SCN10A

2.06e-04112995GO:0019226
GeneOntologyBiologicalProcessoligopeptide import across plasma membrane

SLC15A1 SLC15A2

2.26e-045992GO:0140205
GeneOntologyBiologicalProcessdipeptide import across plasma membrane

SLC15A1 SLC15A2

2.26e-045992GO:0140206
GeneOntologyBiologicalProcesssphingolipid translocation

ABCB1 ABCB4

2.26e-045992GO:0099039
GeneOntologyBiologicalProcessregulation of membrane lipid distribution

ABCB1 ABCB4 P2RX7 TMEM30A

2.70e-0465994GO:0097035
GeneOntologyBiologicalProcessamino acid transmembrane transport

SLC36A4 SLC1A6 SLC47A1 SLC25A29 SLC7A10

2.83e-04120995GO:0003333
GeneOntologyBiologicalProcessxenobiotic detoxification by transmembrane export across the plasma membrane

ABCB1 SLC15A2 SLC47A1

2.89e-0427993GO:1990961
GeneOntologyBiologicalProcessmembrane depolarization

P2RX7 SCN1A SCN4A SCN8A SCN10A

2.95e-04121995GO:0051899
GeneOntologyBiologicalProcesspositive regulation of phospholipid translocation

ABCB4 TMEM30A

3.38e-046992GO:0061092
GeneOntologyBiologicalProcessregulation of membrane potential

SLC1A6 SLC39A8 PANK2 P2RX7 NALCN SCN1A SCN4A SCN7A SCN8A SCN10A

3.54e-045599910GO:0042391
GeneOntologyBiologicalProcessxenobiotic export from cell

ABCB1 SLC15A2 SLC47A1

3.58e-0429993GO:0046618
GeneOntologyBiologicalProcessactin-mediated cell contraction

SCN1A SCN4A SCN7A SCN8A SCN10A

3.68e-04127995GO:0070252
GeneOntologyBiologicalProcessaction potential

P2RX7 SCN1A SCN4A SCN7A SCN8A SCN10A

4.20e-04201996GO:0001508
GeneOntologyBiologicalProcessregulation of phospholipid translocation

ABCB4 TMEM30A

4.71e-047992GO:0061091
GeneOntologyBiologicalProcessalpha-ketoglutarate transport

SLC13A2 SLC22A7

4.71e-047992GO:0015742
GeneOntologyBiologicalProcessthiamine transmembrane transport

SLC19A2 SLC47A1

4.71e-047992GO:0071934
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

SLC12A6 CACNA1F ADCY8 SLC39A8 ITPR3 P2RX7 SCN7A ATP13A3 SLC41A1 ATP2B1 ATP2B4

5.65e-047059911GO:0055080
GeneOntologyBiologicalProcessmonocarboxylic acid transport

SLC22A11 SLC22A7 ABCB4 SLC22A9 P2RX7 SLC26A7

5.70e-04213996GO:0015718
GeneOntologyBiologicalProcessprostaglandin transport

SLC22A11 SLC22A7 P2RX7

5.76e-0434993GO:0015732
GeneOntologyBiologicalProcessheart contraction

SCN1A SCN4A SCN7A SCN8A SCN10A ATP2B1 ATP2B4

5.87e-04298997GO:0060047
GeneOntologyBiologicalProcessdipeptide transport

SLC15A1 SLC15A2

6.27e-048992GO:0042938
GeneOntologyBiologicalProcessthiamine transport

SLC19A2 SLC47A1

6.27e-048992GO:0015888
GeneOntologyBiologicalProcessdipeptide transmembrane transport

SLC15A1 SLC15A2

6.27e-048992GO:0035442
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

SLC12A6 CACNA1F ADCY8 SLC39A8 ITPR3 P2RX7 SCN7A ATP13A3 SLC41A1 ATP2B1 ATP2B4

6.50e-047179911GO:0050801
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

CACNA1F ADCY8 SLC39A8 ITPR3 P2RX7 SCN7A ATP13A3 SLC41A1 ATP2B1 ATP2B4

7.07e-046119910GO:0030003
GeneOntologyBiologicalProcessheart process

SCN1A SCN4A SCN7A SCN8A SCN10A ATP2B1 ATP2B4

7.26e-04309997GO:0003015
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

CACNA1F ADCY8 SLC39A8 ITPR3 P2RX7 SCN7A ATP13A3 SLC41A1 ATP2B1 ATP2B4

8.10e-046229910GO:0006873
GeneOntologyBiologicalProcessactin filament-based movement

SCN1A SCN4A SCN7A SCN8A SCN10A

8.59e-04153995GO:0030048
GeneOntologyBiologicalProcessexport across plasma membrane

ABCB1 SLC15A2 SLC47A1 ATP2B1

9.69e-0491994GO:0140115
GeneOntologyBiologicalProcesstripeptide transmembrane transport

SLC15A1 SLC15A2

1.00e-0310992GO:0035443
GeneOntologyBiologicalProcessexport from cell

TRAPPC11 MICAL1 GALR1 PFKM ADCY8 ABCB1 EFR3A OR51E2 GHRHR P2RX7 SLC15A2 MTNR1A SLC47A1 ATP2B1

1.19e-0311539914GO:0140352
GeneOntologyBiologicalProcesscardiac muscle contraction

SCN1A SCN4A SCN7A SCN8A SCN10A

1.27e-03167995GO:0060048
GeneOntologyBiologicalProcessdetoxification

SLC39A8 ABCB1 AIFM2 SLC15A2 SLC47A1

1.37e-03170995GO:0098754
GeneOntologyBiologicalProcesspositive regulation of lipid transport

GALR1 ABCB4 P2RX7 TMEM30A

1.48e-03102994GO:0032370
GeneOntologyBiologicalProcessdetection of external stimulus

CACNA1F ADGRV1 SCN1A SCN10A OPN5

1.48e-03173995GO:0009581
GeneOntologyBiologicalProcessdetection of abiotic stimulus

CACNA1F ADGRV1 SCN1A SCN10A OPN5

1.56e-03175995GO:0009582
GeneOntologyBiologicalProcesspositive regulation of bone mineralization

ADGRV1 P2RX7 ATP2B1

1.68e-0349993GO:0030501
GeneOntologyBiologicalProcessphospholipid transport

ABCB1 ABCB4 P2RX7 TMEM30A

1.71e-03106994GO:0015914
GeneOntologyBiologicalProcesstripeptide transport

SLC15A1 SLC15A2

1.72e-0313992GO:0042939
GeneOntologyBiologicalProcessaromatic amino acid transport

SLC36A4 SLC25A29

1.72e-0313992GO:0015801
GeneOntologyBiologicalProcessintracellular calcium ion homeostasis

CACNA1F ADCY8 ITPR3 P2RX7 ATP13A3 ATP2B1 ATP2B4

1.73e-03359997GO:0006874
GeneOntologyBiologicalProcessadenylate cyclase-activating G protein-coupled receptor signaling pathway

GALR1 ADCY8 OR51E2 GHRHR ATP2B4

2.29e-03191995GO:0007189
GeneOntologyBiologicalProcessL-arginine transmembrane transport

SLC47A1 SLC25A29

2.30e-0315992GO:1903826
GeneOntologyBiologicalProcesspositive regulation of phospholipid transport

ABCB4 TMEM30A

2.30e-0315992GO:2001140
GeneOntologyCellularComponentapical plasma membrane

SLC12A6 SLC2A7 SLC22A11 PFKM SLC13A2 SLC22A7 ADCY8 SLC39A8 ABCB1 ABCB4 ITPR3 SLC15A1 SLC15A2 SLC26A7 PROM2 TMEM30A SLC47A1 ATP2B1

1.58e-1148710018GO:0016324
GeneOntologyCellularComponentapical part of cell

SLC12A6 SLC2A7 SLC22A11 PFKM SLC13A2 SLC22A7 ADCY8 SLC39A8 ABCB1 ABCB4 ITPR3 SLC15A1 SLC15A2 SLC26A7 PROM2 TMEM30A SLC47A1 ATP2B1

3.77e-1059210018GO:0045177
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN4A SCN7A SCN8A SCN10A

1.34e-08171005GO:0001518
GeneOntologyCellularComponentbasal plasma membrane

SLC12A6 SLC22A11 SLC22A7 ADCY8 SLC39A8 SLC22A9 SLC26A7 PROM2 SLC47A1 SLC41A1 ATP2B1 ATP2B4

1.28e-0735410012GO:0009925
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN4A SCN7A SCN8A SCN10A

2.46e-07291005GO:0034706
GeneOntologyCellularComponentbasal part of cell

SLC12A6 SLC22A11 SLC22A7 ADCY8 SLC39A8 SLC22A9 SLC26A7 PROM2 SLC47A1 SLC41A1 ATP2B1 ATP2B4

2.58e-0737810012GO:0045178
GeneOntologyCellularComponentbasolateral plasma membrane

SLC12A6 SLC22A7 ADCY8 SLC39A8 SLC22A9 SLC26A7 PROM2 SLC47A1 SLC41A1 ATP2B1 ATP2B4

3.84e-0732010011GO:0016323
GeneOntologyCellularComponentmotile cilium

CD52 PFKM TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50 ATP2B4

1.07e-0635510011GO:0031514
GeneOntologyCellularComponentcilium

CACNA1F CD52 ADGRV1 PFKM PROM2 KIF3C TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50 ATP2B4

2.33e-0589810015GO:0005929
GeneOntologyCellularComponentpresynaptic membrane

SLC1A6 ADCY8 SCN1A SCN8A SCN10A ATP2B1 ATP2B4

3.73e-042771007GO:0042734
GeneOntologyCellularComponentintercellular canaliculus

ABCB1 ABCB4

7.98e-0491002GO:0046581
GeneOntologyCellularComponentcation channel complex

CACNA1F SCN1A SCN4A SCN7A SCN8A SCN10A

9.36e-042351006GO:0034703
GeneOntologyCellularComponentneuronal cell body membrane

ADCY8 ATP2B1 CX3CR1

1.14e-03431003GO:0032809
GeneOntologyCellularComponentcell body membrane

ADCY8 ATP2B1 CX3CR1

1.48e-03471003GO:0044298
GeneOntologyCellularComponentneuronal cell body

CACNA1F ADCY8 ITPR3 P2RX7 SCN1A SCN8A MTNR1A KIF3C ATP2B1 SLC7A10 CX3CR1

2.15e-0383510011GO:0043025
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1F NALCN SCN1A SCN4A SCN7A SCN8A SCN10A

2.27e-033781007GO:0034702
HumanPhenoExercise-induced muscle fatigue

TRAPPC11 PFKM SCN4A

3.17e-0512283HP:0009020
HumanPhenoFocal automatism seizure

MICAL1 SCN1A SCN8A

3.17e-0512283HP:0032898
DomainTAS2R

TAS2R14 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

4.96e-1526969PF05296
DomainT2R

TAS2R14 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

4.96e-1526969IPR007960
DomainNa_channel_asu

SCN1A SCN4A SCN7A SCN8A SCN10A

7.97e-1010965IPR001696
DomainNa_trans_assoc

SCN1A SCN4A SCN7A SCN8A SCN10A

7.97e-1010965IPR010526
DomainNa_trans_assoc

SCN1A SCN4A SCN7A SCN8A SCN10A

7.97e-1010965PF06512
DomainChannel_four-helix_dom

CACNA1F NALCN SCN1A SCN4A SCN7A SCN8A SCN10A

1.63e-0857967IPR027359
Domain-

CACNA1F NALCN SCN1A SCN4A SCN7A SCN8A SCN10A

1.63e-08579671.20.120.350
DomainMFS_dom

SLC2A7 SLC22A11 SLC19A2 MFSD6L FLVCR2 SLC22A7 SLC22A9 SLC15A1 SLC15A2

2.94e-08134969IPR020846
DomainIon_trans_dom

CACNA1F ITPR3 NALCN SCN1A SCN4A SCN7A SCN8A SCN10A

1.28e-07114968IPR005821
DomainIon_trans

CACNA1F ITPR3 NALCN SCN1A SCN4A SCN7A SCN8A SCN10A

1.28e-07114968PF00520
DomainMFS

SLC2A7 SLC22A11 MFSD6L FLVCR2 SLC22A7 SLC22A9

1.98e-05108966PS50850
DomainATP2B1/4

ATP2B1 ATP2B4

2.61e-052962IPR030319
DomainOligopep_transport

SLC15A1 SLC15A2

2.61e-052962IPR004768
DomainPTR2_symporter_CS

SLC15A1 SLC15A2

7.82e-053962IPR018456
DomainPTR2_1

SLC15A1 SLC15A2

7.82e-053962PS01022
DomainATPase_P-typ_cation-transptr_C

ATP13A3 ATP2B1 ATP2B4

8.49e-0517963IPR006068
DomainCation_ATPase_C

ATP13A3 ATP2B1 ATP2B4

8.49e-0517963PF00689
DomainIQ_motif_EF-hand-BS

SCN1A SCN4A SCN7A SCN8A SCN10A

1.01e-0490965IPR000048
DomainCation_ATPase_N

ATP13A3 ATP2B1 ATP2B4

1.02e-0418963PF00690
DomainATPase_P-typ_cation-transptr_N

ATP13A3 ATP2B1 ATP2B4

1.20e-0419963IPR004014
DomainATP_Ca_trans_C

ATP2B1 ATP2B4

1.56e-044962IPR022141
DomainATP_Ca_trans_C

ATP2B1 ATP2B4

1.56e-044962PF12424
DomainP-type_ATPase_IIB

ATP2B1 ATP2B4

1.56e-044962IPR006408
DomainPTR2_2

SLC15A1 SLC15A2

1.56e-044962PS01023
DomainGPCR_Rhodpsn_7TM

VN1R2 GALR1 OR1S1 FPR1 OR51E2 OR2B11 OR2A12 GPR142 MTNR1A OPN5 GPR176 CX3CR1

1.63e-046709612IPR017452
DomainG_PROTEIN_RECEP_F1_1

VN1R2 GALR1 OR1S1 FPR1 OR51E2 OR2B11 OR2A12 GPR142 MTNR1A OPN5 GPR176 CX3CR1

2.01e-046859612PS00237
DomainG_PROTEIN_RECEP_F1_2

VN1R2 GALR1 OR1S1 FPR1 OR51E2 OR2B11 OR2A12 GPR142 MTNR1A OPN5 GPR176 CX3CR1

2.17e-046919612PS50262
DomainGPCR_Rhodpsn

VN1R2 GALR1 OR1S1 FPR1 OR51E2 OR2B11 OR2A12 GPR142 MTNR1A OPN5 GPR176 CX3CR1

2.20e-046929612IPR000276
DomainPOT_fam

SLC15A1 SLC15A2

2.59e-045962IPR000109
DomainPTR2

SLC15A1 SLC15A2

2.59e-045962PF00854
DomainNa_trans_cytopl

SCN1A SCN8A

3.87e-046962PF11933
DomainNa_trans_cytopl

SCN1A SCN8A

3.87e-046962IPR024583
DomainIQ

SCN1A SCN4A SCN8A SCN10A

4.89e-0471964PF00612
DomainMFS_1

SLC22A11 FLVCR2 SLC22A7 SLC22A9

6.66e-0477964PF07690
DomainMFS

SLC22A11 FLVCR2 SLC22A7 SLC22A9

6.66e-0477964IPR011701
Domain7tm_1

GALR1 OR1S1 FPR1 OR51E2 OR2B11 OR2A12 GPR142 MTNR1A OPN5 GPR176 CX3CR1

7.04e-046779611PF00001
DomainATPase_P-typ_cyto_domN

ATP13A3 ATP2B1 ATP2B4

7.64e-0435963IPR023299
DomainIQ

SCN1A SCN4A SCN7A SCN8A

8.06e-0481964SM00015
DomainP_typ_ATPase

ATP13A3 ATP2B1 ATP2B4

8.31e-0436963IPR001757
DomainATPase_P-typ_P_site

ATP13A3 ATP2B1 ATP2B4

8.31e-0436963IPR018303
DomainATPASE_E1_E2

ATP13A3 ATP2B1 ATP2B4

8.31e-0436963PS00154
DomainATPase_P-typ_transduc_dom_A

ATP13A3 ATP2B1 ATP2B4

9.01e-0437963IPR008250
DomainE1-E2_ATPase

ATP13A3 ATP2B1 ATP2B4

9.01e-0437963PF00122
DomainG_PROTEIN_RECEP_F2_1

ADGRV1 GHRHR CELSR1

1.13e-0340963PS00649
DomainGPCR_2_extracellular_dom

ADGRV1 GHRHR CELSR1

1.13e-0340963IPR001879
DomainG_PROTEIN_RECEP_F2_3

ADGRV1 GHRHR CELSR1

1.13e-0340963PS50227
DomainIQ

SCN1A SCN4A SCN8A SCN10A

1.35e-0393964PS50096
DomainG_PROTEIN_RECEP_F2_2

ADGRV1 GHRHR CELSR1

2.17e-0350963PS00650
Domain7tm_2

ADGRV1 GHRHR CELSR1

2.17e-0350963PF00002
Domain-

ATP2B1 ATP2B4

2.99e-03169621.20.1110.10
DomainATPase_P-typ_TM_dom

ATP2B1 ATP2B4

2.99e-0316962IPR023298
DomainGPCR_2_secretin-like

ADGRV1 GHRHR CELSR1

3.64e-0360963IPR000832
DomainGPCR_2-like

ADGRV1 GHRHR CELSR1

3.64e-0360963IPR017981
DomainCation_ATPase_N

ATP2B1 ATP2B4

3.79e-0318962SM00831
DomainG_PROTEIN_RECEP_F2_4

ADGRV1 GHRHR CELSR1

3.82e-0361963PS50261
DomainConA-like_dom

ADGRV1 CELSR1 FAT2 SEL1L3 TRIM47

5.46e-03219965IPR013320
DomainAA-permease/SLC12A_dom

SLC12A6 SLC7A10

5.65e-0322962IPR004841
DomainAA_permease

SLC12A6 SLC7A10

5.65e-0322962PF00324
DomainABC_membrane

ABCB1 ABCB4

6.70e-0324962PF00664
DomainHormR

GHRHR CELSR1

7.26e-0325962SM00008
DomainHAD-like_dom

ATP13A3 ATP2B1 ATP2B4

7.85e-0379963IPR023214
DomainABC_TM1F

ABCB1 ABCB4

9.06e-0328962PS50929
DomainABC1_TM_dom

ABCB1 ABCB4

9.06e-0328962IPR011527
DomainHRM

GHRHR CELSR1

9.06e-0328962PF02793
PathwayREACTOME_SENSORY_PERCEPTION_OF_TASTE

ITPR3 TAS2R14 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

4.55e-16317610MM15691
PathwayKEGG_TASTE_TRANSDUCTION

ADCY8 ITPR3 TAS2R14 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R46 TAS2R50

1.48e-13527610M5785
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

TAS2R14 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

2.60e-1337769MM15067
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC12A6 SLC36A4 SLC2A7 SLC22A11 SLC13A2 SLC1A6 SLC22A7 SLC39A8 SLC15A1 SLC15A2 SLC26A7 SLC47A1 SLC25A29 SLC41A1 SLC7A10

3.63e-122497615M5988
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

TAS2R14 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

2.63e-1139768M793
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC12A6 SLC36A4 SLC2A7 SLC13A2 SLC1A6 SLC22A7 SLC39A8 SLC15A1 SLC15A2 SLC26A7 SLC47A1 SLC25A29 SLC41A1 SLC7A10

2.83e-112387614MM15076
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

GALR1 FPR1 ADCY8 TAS2R14 MTNR1A OPN5 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50 CX3CR1

3.06e-112897615MM15057
PathwayWP_GPCRS_ODORANT

GPR137 TAS2R14 GPR142 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50 GPR176

4.00e-111577612MM15872
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

GALR1 FPR1 ADCY8 ITPR3 TAS2R14 MTNR1A OPN5 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50 CX3CR1

9.86e-113147615M600
PathwayREACTOME_SENSORY_PERCEPTION_OF_TASTE

ITPR3 TAS2R14 TAS2R31 TAS2R43 TAS2R20 TAS2R30 TAS2R46 TAS2R50

1.30e-1047768M42524
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC12A6 SLC36A4 SLC2A7 SLC22A11 SLC13A2 SLC1A6 SLC22A7 ADCY8 SLC39A8 ABCB1 ABCB4 NALCN SLC15A1 SLC15A2 SLC26A7 SLC47A1 SLC25A29 SLC41A1 ATP2B1 SLC7A10 ATP2B4

1.71e-107367621M27287
PathwayREACTOME_SENSORY_PERCEPTION

ITPR3 OR51E2 OR2B11 TAS2R14 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

3.71e-101907612MM15687
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC12A6 SLC36A4 SLC2A7 SLC13A2 SLC1A6 SLC22A7 SLC39A8 ABCB1 ABCB4 NALCN SLC15A1 SLC15A2 SLC26A7 SLC47A1 SLC25A29 SLC41A1 ATP2B1 SLC7A10 ATP2B4

2.21e-096817619MM14985
PathwayREACTOME_SIGNALING_BY_GPCR

GALR1 FPR1 ADCY8 ITPR3 GHRHR TAS2R14 MTNR1A OPN5 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50 GPR176 CX3CR1

6.50e-096467618MM14962
PathwayREACTOME_GPCR_LIGAND_BINDING

GALR1 FPR1 GHRHR TAS2R14 MTNR1A OPN5 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50 CX3CR1

7.47e-094307615MM15160
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC12A6 SLC36A4 SLC1A6 SLC15A1 SLC15A2 SLC26A7 SLC25A29 SLC7A10

1.12e-07108768M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC12A6 SLC36A4 SLC1A6 SLC15A1 SLC15A2 SLC26A7 SLC25A29 SLC7A10

1.20e-07109768MM15074
PathwayREACTOME_SIGNALING_BY_GPCR

GALR1 FPR1 ADCY8 ITPR3 GHRHR TAS2R14 MTNR1A OPN5 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50 GPR176 CX3CR1

1.42e-077027617M746
PathwayREACTOME_GPCR_LIGAND_BINDING

GALR1 FPR1 GHRHR TAS2R14 MTNR1A OPN5 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50 CX3CR1

1.49e-074637614M507
PathwayREACTOME_CARDIAC_CONDUCTION

ITPR3 SCN1A SCN4A SCN7A SCN8A SCN10A ATP2B1 ATP2B4

4.69e-07130768M27454
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN1A SCN4A SCN7A SCN8A SCN10A

6.07e-0731765M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN1A SCN4A SCN7A SCN8A SCN10A

7.16e-0732765M27455
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC22A11 SLC13A2 SLC22A7 SLC39A8 SLC47A1 SLC41A1

5.85e-0684766M27334
PathwayREACTOME_SENSORY_PERCEPTION

OR1S1 OR4C45 ITPR3 OR51E2 OR2B11 TAS2R14 OR2A12 TAS2R31 TAS2R43 TAS2R20 TAS2R30 TAS2R46 TAS2R50 ATP2B1

6.45e-066367614M41834
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ITPR3 P2RX7 ATP2B1 ATP2B4

1.25e-0527764MM15053
PathwayREACTOME_MUSCLE_CONTRACTION

ITPR3 SCN1A SCN4A SCN7A SCN8A SCN10A ATP2B1 ATP2B4

1.31e-05203768M5485
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ITPR3 P2RX7 ATP2B1 ATP2B4

1.45e-0528764M924
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC13A2 SLC22A7 SLC39A8 SLC47A1 SLC41A1

5.46e-0576765MM15072
PathwayWP_GPCRS_NONODORANT

GALR1 FPR1 GHRHR CELSR1 TAS2R14 MTNR1A OPN5 CX3CR1

9.00e-05266768MM15843
PathwayWP_PROXIMAL_TUBULE_TRANSPORT

SLC22A11 SLC22A7 ABCB1 SLC47A1

2.48e-0457764M39812
PathwayREACTOME_ORGANIC_ANION_TRANSPORT

SLC22A11 SLC22A7

2.84e-045762M27469
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1F ADCY8 ITPR3 P2RX7 ATP2B1 ATP2B4

3.92e-04178766M2890
PathwayBIOCARTA_MRP_PATHWAY

ABCB1 ABCB4

4.24e-046762M22078
PathwayREACTOME_L1CAM_INTERACTIONS

SCN1A SCN4A SCN7A SCN8A SCN10A

4.87e-04121765M872
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC36A4 SLC25A29 SLC7A10

6.67e-0432763MM14957
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC36A4 SLC25A29 SLC7A10

7.31e-0433763M188
PathwayREACTOME_PLATELET_HOMEOSTASIS

ITPR3 P2RX7 ATP2B1 ATP2B4

7.46e-0476764MM15051
PathwayWP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION

ITPR3 ATP2B1 ATP2B4

9.46e-0436763M39831
PathwayREACTOME_PLATELET_HOMEOSTASIS

ITPR3 P2RX7 ATP2B1 ATP2B4

1.19e-0386764M916
PathwayWP_GPCRS_OTHER

ADGRV1 GHRHR CELSR1 GPR176

1.58e-0393764M39629
PathwayREACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS

ATP2B1 ATP2B4

1.83e-0312762M27326
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR3 P2RX7

2.15e-0313762MM14553
PathwayREACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS

ATP2B1 ATP2B4

2.50e-0314762MM15052
PathwayREACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT

SLC22A11 SLC22A7

2.88e-0315762M888
PathwayREACTOME_ION_HOMEOSTASIS

ITPR3 ATP2B1 ATP2B4

3.07e-0354763M27460
PathwayREACTOME_ION_HOMEOSTASIS

ITPR3 ATP2B1 ATP2B4

3.07e-0354763MM15202
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR3 P2RX7

3.28e-0316762M26945
PathwayKEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY

ADCY8 CX3CR1

3.70e-0317762M47544
Pubmed

Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.

TAS2R14 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

6.57e-2113100915938754
Pubmed

The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.

TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

1.72e-1812100812379855
Pubmed

A novel family of mammalian taste receptors.

TAS2R14 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

2.65e-1821100910761934
Pubmed

Evolutionary relationships of the Tas2r receptor gene families in mouse and human.

TAS2R14 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

4.48e-1822100912734386
Pubmed

Receptors for bitter and sweet taste.

TAS2R14 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

1.83e-1725100912139982
Pubmed

Molecular mechanisms of bitter and sweet taste transduction.

TAS2R14 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

2.79e-1726100911696554
Pubmed

Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.

TAS2R14 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

4.17e-1727100912581520
Pubmed

Mapping of QTLs for oral alcohol self-administration in B6.C and B6.I quasi-congenic RQI strains.

TAS2R14 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

1.26e-1630100917273929
Pubmed

Adaptive diversification of bitter taste receptor genes in Mammalian evolution.

TAS2R14 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

1.26e-1630100912679530
Pubmed

The molecular receptive ranges of human TAS2R bitter taste receptors.

TAS2R14 TAS2R45 TAS2R31 TAS2R43 TAS2R19 TAS2R30 TAS2R46 TAS2R50

1.66e-1523100820022913
Pubmed

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.

TAS2R14 TAS2R45 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

1.04e-1428100815744053
Pubmed

Evolution of bitter taste receptors in humans and apes.

TAS2R14 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

5.99e-1434100815496549
Pubmed

Identification and characterization of human taste receptor genes belonging to the TAS2R family.

TAS2R31 TAS2R43 TAS2R20 TAS2R46 TAS2R50

2.24e-1013100512584440
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN4A SCN8A SCN10A

8.02e-099100416382098
Pubmed

Opposing effects of the purinergic P2X7 receptor on seizures in neurons and microglia in male mice.

P2RX7 SCN1A CX3CR1

2.31e-083100338777288
Pubmed

Screening of the interaction between xenobiotic transporters and PDZ proteins.

SLC22A11 SLC22A9 SLC15A1 SLC15A2

8.57e-0815100415553237
Pubmed

Isolation of a family of organic anion transporters from human liver and kidney.

SLC22A11 SLC22A7 SLC22A9

9.21e-084100311327718
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1F P2RX7 SCN1A SCN4A SCN7A SCN8A SCN10A

1.64e-07139100716985003
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN8A SCN10A

4.58e-076100323652591
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN4A SCN8A

1.91e-069100315746173
Pubmed

L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.

SLC13A2 SLC1A6 GHRHR P2RX7 SLC15A1 SLC15A2

3.77e-06143100620424473
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1F ITPR3 ATP2B1 ATP2B4

4.41e-0638100430786075
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN8A SCN10A

6.46e-0613100315123669
Pubmed

Use of a peptide mimotope to guide the humanization of MRK-16, an anti-P-glycoprotein monoclonal antibody.

ABCB1 ABCB4

8.18e-062100210488067
Pubmed

Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin.

TAS2R31 TAS2R43

8.18e-062100217702579
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

8.18e-062100237901435
Pubmed

Multidrug resistance gene expression and ABCB1 SNPs in plasma cell myeloma.

ABCB1 ABCB4

8.18e-062100221705081
Pubmed

The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids.

ABCB1 ABCB4

8.18e-062100210552998
Pubmed

Differential Coupling of Binding, ATP Hydrolysis, and Transport of Fluorescent Probes with P-Glycoprotein in Lipid Nanodiscs.

ABCB1 ABCB4

8.18e-062100228441502
Pubmed

Bitter Sensing TAS2R50 Mediates the trans-Resveratrol-Induced Anti-inflammatory Effect on Interleukin 6 Release in HGF-1 Cells in Culture.

TAS2R43 TAS2R50

8.18e-062100233461297
Pubmed

Genetic dissection of the function of mammalian P-glycoproteins.

ABCB1 ABCB4

8.18e-06210029196326
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

8.18e-062100226410685
Pubmed

Importance of a small N-terminal region in mammalian peptide transporters for substrate affinity and function.

SLC15A1 SLC15A2

8.18e-062100211944083
Pubmed

MDR1 and MDR3 genes and drug resistance to cisplatin of ovarian cancer cells.

ABCB1 ABCB4

8.18e-062100218231753
Pubmed

Functional and structural demonstration of the presence of Ca-ATPase (PMCA) in both microvillous and basal plasma membranes from syncytiotrophoblast of human term placenta.

ATP2B1 ATP2B4

8.18e-062100218657858
Pubmed

Effects of cellular, chemical, and pharmacological chaperones on the rescue of a trafficking-defective mutant of the ATP-binding cassette transporter proteins ABCB1/ABCB4.

ABCB1 ABCB4

8.18e-062100222184139
Pubmed

Comparison of human and monkey peptide transporters: PEPT1 and PEPT2.

SLC15A1 SLC15A2

8.18e-062100215981923
Pubmed

Novel drug transporter substrates identification: An innovative approach based on metabolomic profiling, in silico ligand screening and biological validation.

SLC15A2 SLC47A1

8.18e-062100237775020
Pubmed

Isolation and expression of a complementary DNA that confers multidrug resistance.

ABCB1 ABCB4

8.18e-06210023022150
Pubmed

ABCB1/4 gallbladder cancer risk variants identified in India also show strong effects in Chileans.

ABCB1 ABCB4

8.18e-062100232058310
Pubmed

Peptide transporters and their roles in physiological processes and drug disposition.

SLC15A1 SLC15A2

8.18e-062100218668438
Pubmed

Macrophages facilitate peripheral nerve regeneration by organizing regeneration tracks through Plexin-B2.

PLXNB2 CX3CR1

8.18e-062100235086862
Pubmed

Mammalian multidrug-resistance gene: correlation of exon organization with structural domains and duplication of an ancestral gene.

ABCB1 ABCB4

8.18e-06210022570420
Pubmed

MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine.

ABCB1 ABCB4

8.18e-06210028898203
Pubmed

Lack of interaction between the peptidomimetic substrates captopril and cephradine.

SLC15A1 SLC15A2

8.18e-062100219246733
Pubmed

The influence of membrane lipid structure on plasma membrane Ca2+ -ATPase activity.

ATP2B1 ATP2B4

8.18e-062100216412504
Pubmed

The human P2X7 receptor alters microglial morphology and cytokine secretion following immunomodulation.

P2RX7 CX3CR1

8.18e-062100237101546
Pubmed

Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes.

ABCB1 ABCB4

8.18e-06210022473069
Pubmed

Common genetic variation and risk of gallbladder cancer in India: a case-control genome-wide association study.

ABCB1 ABCB4

8.18e-062100228274756
Pubmed

Distinct roles of PMCA isoforms in Ca2+ homeostasis of bladder smooth muscle: evidence from PMCA gene-ablated mice.

ATP2B1 ATP2B4

8.18e-062100216956963
Pubmed

Transport of angiotensin-converting enzyme inhibitors by H+/peptide transporters revisited.

SLC15A1 SLC15A2

8.18e-062100218713951
Pubmed

A missense mutation in ABCB4 gene involved in progressive familial intrahepatic cholestasis type 3 leads to a folding defect that can be rescued by low temperature.

ABCB1 ABCB4

8.18e-062100219185004
Pubmed

Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins.

ABCB1 ABCB4

8.18e-06210023768958
Pubmed

The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8+ T cells.

P2RX7 CX3CR1

8.18e-062100229973721
Pubmed

Molecular mechanism of dipeptide and drug transport by the human renal H+/oligopeptide cotransporter hPEPT2.

SLC15A1 SLC15A2

8.18e-062100218367661
Pubmed

Localization of two genes encoding plasma membrane Ca2(+)-transporting ATPases to human chromosomes 1q25-32 and 12q21-23.

ATP2B1 ATP2B4

8.18e-06210021674727
Pubmed

[Pharmacogenetic criteria of drug-resistant epilepsy].

ABCB1 SCN1A

8.18e-062100223786015
Pubmed

Tissue distribution and thyroid hormone regulation of Pept1 and Pept2 mRNA in rodents.

SLC15A1 SLC15A2

8.18e-062100216202478
Pubmed

Bitter taste receptors for saccharin and acesulfame K.

TAS2R31 TAS2R43

8.18e-062100215537898
Pubmed

Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response.

ABCB1 CX3CR1

8.18e-062100212545080
Pubmed

Role of ABCB1 and ABCB4 in renal and biliary excretion of perfluorooctanoic acid in mice.

ABCB1 ABCB4

8.18e-062100238522903
Pubmed

Localization of the human multiple drug resistance gene, MDR1, to 7q21.1.

ABCB1 ABCB4

8.18e-06210023477522
Pubmed

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.

SCN1A SCN8A

8.18e-062100233411788
Pubmed

The bioactive dipeptide anserine is transported by human proton-coupled peptide transporters.

SLC15A1 SLC15A2

8.18e-062100220067523
Pubmed

Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression.

ABCB1 ABCB4

8.18e-062100218215618
Pubmed

Targeted ablation of plasma membrane Ca2+-ATPase (PMCA) 1 and 4 indicates a major housekeeping function for PMCA1 and a critical role in hyperactivated sperm motility and male fertility for PMCA4.

ATP2B1 ATP2B4

8.18e-062100215178683
Pubmed

Clinical factors and ABCB1 polymorphisms in prediction of antiepileptic drug response: a prospective cohort study.

ABCB1 ABCB4

8.18e-062100216857572
Pubmed

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

SCN1A SCN8A

8.18e-062100231943325
Pubmed

Asc-1 Transporter Regulation of Synaptic Activity via the Tonic Release of d-Serine in the Forebrain.

ABCB1 SLC7A10

8.18e-062100226796213
Pubmed

Physical mapping, amplification, and overexpression of the mouse mdr gene family in multidrug-resistant cells.

ABCB1 ABCB4

8.18e-06210021969609
Pubmed

Expression of MDR1 and MDR3 gene products in paclitaxel-, doxorubicin- and vincristine-resistant cell lines.

ABCB1 ABCB4

8.18e-062100224140176
Pubmed

Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis.

ABCB1 ABCB4

8.18e-06210029419367
Pubmed

Cell-specific activity of cis-acting regulatory elements in the promoter of the mouse multidrug resistance gene mdr1.

ABCB1 ABCB4

8.18e-06210022248681
Pubmed

Role of plasma membrane Ca2+-ATPase in contraction-relaxation processes of the bladder: evidence from PMCA gene-ablated mice.

ATP2B1 ATP2B4

8.18e-062100216291816
Pubmed

Regulation of plasma membrane Ca2+-ATPase by small GTPases and phosphoinositides in human platelets.

ATP2B1 ATP2B4

8.18e-062100210748016
Pubmed

The role of multiple drug resistance proteins in fetal and/or placental protection against teratogen-induced orofacial clefting.

ABCB1 ABCB4

8.18e-062100217440929
Pubmed

Selective upregulation of the expression of plasma membrane calcium ATPase isoforms upon differentiation and 1,25(OH)2D3-vitamin treatment of colon cancer cells.

ATP2B1 ATP2B4

8.18e-062100226116539
Pubmed

Amplification of the murine mdr2 gene and a reconsideration of the structure of the murine mdr gene locus.

ABCB1 ABCB4

8.18e-06210027832992
Pubmed

Mdr P-glycoproteins are not essential for biliary excretion of the hydrophobic heme precursor protoporphyrin in a griseofulvin-induced mouse model of erythropoietic protoporphyria.

ABCB1 ABCB4

8.18e-062100211826402
Pubmed

What have we learnt thus far from mice with disrupted P-glycoprotein genes?

ABCB1 ABCB4

8.18e-06210028763339
Pubmed

Quantification of Hepatic Organic Anion Transport Proteins OAT2 and OAT7 in Human Liver Tissue and Primary Hepatocytes.

SLC22A7 SLC22A9

8.18e-062100229906129
Pubmed

Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.

SCN1A SCN8A

8.18e-062100237665666
Pubmed

The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.

SCN1A SCN8A

8.18e-062100217881658
Pubmed

Plasma membrane calcium ATPase regulates bone mass by fine-tuning osteoclast differentiation and survival.

ATP2B1 ATP2B4

8.18e-062100223266958
Pubmed

Biliary secretion of alpha-tocopherol and the role of the mdr2 P-glycoprotein in rats and mice.

ABCB1 ABCB4

8.18e-06210029473291
Pubmed

mdr1a-encoded P-glycoprotein is not required for peripheral T cell proliferation, cytokine release, or cytotoxic effector function in mice.

ABCB1 ABCB4

8.18e-062100210453001
Pubmed

The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues.

ABCB1 ABCB4

8.18e-06210022471060
Pubmed

Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta.

SLC22A11 SLC22A9

8.18e-062100210660625
Pubmed

Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors.

SLC22A11 SLC22A7

8.18e-062100212023506
Pubmed

In vitro studies with two human organic anion transporters: OAT2 and OAT7.

SLC22A7 SLC22A9

8.18e-062100228945155
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

SCAMP4 ATL3 GOLT1B PLXNB2 TRAM1 TMEM30A ATP13A3 ATP2B4 GPR176

1.44e-05499100922810586
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

SLC22A11 SLC22A7 ABCB1 ABCB4 SLC15A1 SLC15A2

2.09e-05193100619343046
Pubmed

Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse.

ABCB1 ABCB4

2.45e-05310027814632
Pubmed

Immunolocalization of ABC drug transporters in human placenta from normal and gestational diabetic pregnancies.

ABCB1 ABCB4

2.45e-053100225029804
Pubmed

Transbilayer movement of NBD-labeled phospholipids in red blood cell membranes: outward-directed transport by the multidrug resistance protein 1 (MRP1).

ABCB1 ABCB4

2.45e-05310029778357
Pubmed

Upregulation of P2RX7 in Cx3cr1-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1β Secretion and Photoreceptor Neurodegeneration.

P2RX7 CX3CR1

2.45e-053100225948251
Pubmed

Selected ABCB1, ABCB4 and ABCC2 polymorphisms do not enhance the risk of drug-induced hepatotoxicity in a Spanish cohort.

ABCB1 ABCB4

2.45e-053100224732756
Pubmed

A complex of Neuroplastin and Plasma Membrane Ca2+ ATPase controls T cell activation.

ATP2B1 ATP2B4

2.45e-053100228827723
Pubmed

Differences between nuclear run-off and mRNA levels for multidrug resistance gene expression in the cephalocaudal axis of the mouse intestine.

ABCB1 ABCB4

2.45e-05310028547326
Pubmed

Intracellular expression of P-170 glycoprotein in peripheral blood mononuclear cell subsets from healthy donors and HIV-infected patients.

ABCB1 ABCB4

2.45e-05310029542318
InteractionSCN11A interactions

NALCN SCN1A SCN8A SCN10A

4.07e-0715864int:SCN11A
InteractionC2CD4B interactions

ADGRV1 PLXNB2 CELSR1 SCN4A

3.68e-0544864int:C2CD4B
InteractionCCR6 interactions

SLC19A2 ABCB1 ITPR3 ATP13A3 ATP2B4

3.94e-0589865int:CCR6
InteractionLGALS9B interactions

SLC12A6 ABCB1 ATP13A3 ATP2B4

4.03e-0545864int:LGALS9B
InteractionSGPP1 interactions

GOLT1B SLC39A8 SLC22A9 SLC15A1

4.40e-0546864int:SGPP1
InteractionSCN5A interactions

NALCN SCN1A SCN8A SCN10A

4.79e-0547864int:SCN5A
InteractionOR2G6 interactions

SLC12A6 SLC47A1 ATP2B4

5.85e-0518863int:OR2G6
Cytoband12p13.2

TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

6.41e-124597712p13.2
CytobandEnsembl 112 genes in cytogenetic band chr12p13

TAS2R14 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

9.00e-07353978chr12p13
Cytoband11q13.1

SLC22A11 ATL3 SLC22A9

3.31e-046397311q13.1
Cytoband13q32.3

NALCN SLC15A1

1.09e-032397213q32.3
GeneFamilyTaste 2 receptors

TAS2R14 TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50

1.09e-173981111162
GeneFamilySolute carriers

SLC12A6 SLC36A4 SLC2A7 SLC22A11 SLC19A2 FLVCR2 SLC13A2 SLC1A6 SLC22A7 SLC39A8 SLC22A9 SLC15A1 SLC15A2 SLC26A7 SLC47A1 SLC25A29 SLC41A1 SLC7A10

1.14e-133958118752
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN4A SCN8A SCN10A

4.63e-0898141203
GeneFamilyATPases Ca2+ transporting

ATP2B1 ATP2B4

6.99e-0498121209
GeneFamilyATP binding cassette subfamily B

ABCB1 ABCB4

1.06e-0311812806
GeneFamilyCD molecules|Tetraspanins

TSPAN19 TSPAN14

9.57e-0333812768
CoexpressionAtlasDevelopingKidney_e15.5_Podocyte cells_emap-27915_top-relative-expression-ranked_1000

CHST9 CELSR1 PANK2 P2RX7 NALCN SLC26A7 SCN7A SCN8A SEL1L3 SLC47A1 ATP13A3 TMEM26 CX3CR1

1.57e-058368113gudmap_developingKidney_e15.5_Podocyte cells_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_top-relative-expression-ranked_1000

SLC19A2 MFSD6L FLVCR2 RASSF7 SLC39A8 EFR3A FAT2 SLC15A2 PROM2 SCN8A SLC47A1 ATP13A3

4.02e-057848112gudmap_developingLowerUrinaryTract_e15.5_urothelium_1000
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A11 SLC13A2 SLC22A7 ADCY8 SLC39A8 FARP1 SLC47A1

1.49e-071829774a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 SLC22A11 SLC13A2 SLC22A7 SLC39A8 FARP1 SLC47A1

1.61e-071849779434731f651820b05335085582960f08fbf895de
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1F FLVCR2 TMEM255B CELSR1 NALCN TSPAN14 SLC41A1

1.67e-07185977241ea1e178fffef9e7df971de739e794332d5173
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CHST9 ADGRV1 RASSF7 ITPR3 CELSR1 TMEM62 SEL1L3

2.15e-07192977d3634574b2e8d2ded6446969361b70761b331aea
ToppCellCOVID-19-lung-Secretory|COVID-19 / Disease (COVID-19 only), tissue and cell type

CHST9 ADGRV1 CELSR1 FAT2 SLC15A2 PROM2 SEL1L3

2.15e-0719297759261098ccb52306f837f632ebaea45b90ad30fe
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN19 TMEM255B ARAP3 NALCN KIF3C SLC41A1

2.19e-061739767dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1F FLVCR2 RASSF7 CELSR1 SLC15A2 FARP1

2.85e-06181976b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRV1 SLC13A2 SLC22A7 ADCY8 FARP1 SLC47A1

3.03e-06183976d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCellfacs-Trachea-3m-Epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASSF7 CELSR1 FAT2 SLC15A2 SLC26A7 PROM2

3.65e-06189976f8959cc2c14899c8dfeb1b5e51e187537df2f03e
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

CHST9 ADGRV1 CELSR1 FAT2 PROM2 SEL1L3

3.65e-0618997684d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PFKM CELSR1 SLC15A2 FARP1 SLC41A1 SLC7A10

4.00e-06192976261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A11 SLC13A2 SLC22A7 SLC39A8 FARP1 SLC47A1

4.00e-061929763e1a4cb0d83efd502c8613d41a1692bdda5860ed
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

CACNA1F ADGRV1 SLC13A2 PLXNB2 SLC39A8 SCN1A

4.63e-061979761a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CACNA1F ADGRV1 SLC13A2 PLXNB2 SLC39A8 CELSR1

4.77e-06198976285f729140b1df029c24f6ca1d2438470ac51794
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CACNA1F FLVCR2 ADGRV1 CELSR1 SLC15A2 FARP1

5.05e-062009768683445ad5b70748c4a1f12eb77d47623085147e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY8 SLC39A8 GHRHR FARP1 SEL1L3

1.25e-051379750aa4e14b32da0cda677cc0ed6ae470f6ecd77bea
ToppCelldroplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCB1 SLC15A2 TRIM47 GPR176 CX3CR1

3.53e-05170975f664c7559e383b37845c123e41a3be316d869ba0
ToppCelldroplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCB1 SLC15A2 TRIM47 GPR176 CX3CR1

3.53e-051709750272eb1487c2545d4aa06f5d1cd77f823e1441e9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHST9 SLC39A8 FARP1 SEL1L3 ATP13A3

4.06e-05175975284fdc7a9d303636a637041846850d19d114861a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 SLC22A11 SLC22A7 FARP1 SLC47A1

4.28e-051779752f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC22A11 ABCB1 SLC15A1 FARP1 SLC47A1

4.64e-05180975358923e4228035a3e90e2957392089219e90dcd7
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC22A11 ABCB1 SLC15A1 FARP1 SLC47A1

4.64e-05180975864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHST9 SLC39A8 ABCB1 FARP1 SEL1L3

4.76e-051819756956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC22A11 SLC22A7 ABCB1 SLC15A1 SLC47A1

4.76e-051819756980ea624151da32b7f537f263e40fcb87a02e81
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A11 SLC13A2 SLC22A7 ADCY8 SLC47A1

4.89e-05182975e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCellControl-Epithelial_alveolar-AT_1-AT1-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLVCR2 RASSF7 SLC39A8 CELSR1 SLC15A2

4.89e-05182975a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHST9 SLC39A8 ABCB1 FARP1 SEL1L3

4.89e-051829755e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CHST9 CELSR1 SLC15A2 PROM2 SEL1L3

4.89e-051829753f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A11 SLC13A2 SLC22A7 ADCY8 SLC47A1

4.89e-0518297557bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM255B ITPR3 ATP13A3 TRIM47 ATP2B1

5.02e-051839753427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASSF7 CELSR1 FAT2 SLC15A2 PROM2

5.15e-0518497545ff845ceed5960a997545c1009012b65e377d50
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASSF7 CELSR1 FAT2 SLC15A2 PROM2

5.15e-051849752cc2646dee3c6001f7c10b7449c17d1935021958
ToppCellE12.5-Endothelial-capillary_endothelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM255B SLC39A8 ARAP3 SCN7A TRIM47

5.28e-05185975e005d3c01a908157f780bbc1d53dd2ed814a39d2
ToppCellE12.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM255B SLC39A8 ARAP3 SCN7A TRIM47

5.28e-051859750bccc424d0466f7f82baa00127c733640a2d50fb
ToppCellControl-Epithelial_alveolar|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLVCR2 RASSF7 SLC39A8 CELSR1 SLC15A2

5.28e-051859753937e026add96a396122139daf8011cfbc60e75c
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC22A11 SLC22A7 SLC15A1 FARP1 SLC47A1

5.28e-051859751bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Mgp-Endothelial_Tip.Dcn.Mgp-Penk_(Penk)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

HSF2BP FAT2 SLC26A7 SLC47A1

5.33e-05949748fb9adf0db3b0007204716869d895700cbdc6231
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CHST9 SLC39A8 ABCB1 FARP1 SEL1L3

5.42e-051869755c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLVCR2 RASSF7 CELSR1 SLC15A2 FARP1

5.42e-051869753aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REC114 PFKM SLC39A8 ABCB4 ATP2B4

5.42e-05186975ac6e32cf07f0f013101ca7aedae0c562857f182b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 SLC22A11 SLC13A2 SLC22A7 SLC47A1

5.42e-05186975a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REC114 PFKM SLC39A8 ABCB4 ATP2B4

5.42e-051869757cdcf507a9a1349ed2cf62b79116367c3fc732dd
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

SLC22A11 SLC15A1 FARP1 SEL1L3 SLC47A1

5.56e-05187975d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REC114 PFKM SLC39A8 ABCB4 ATP2B4

5.56e-05187975dceca7ae3dae96078cccc17a0d8a61b06fa6dffb
ToppCellP03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM255B ITPR3 ATP13A3 TRIM47 ATP2B1

5.56e-0518797566ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

FLVCR2 ABCB1 SLC15A1 SEL1L3 SLC47A1

5.56e-05187975acd305475f3609800af0d7bc68d83ef41228080b
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____podocyte-2|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST9 RASSF7 SLC39A8 GHRHR OPN5

5.70e-05188975c300accbac71a3bc075fe985543d8a8ead82531b
ToppCelldroplet-Lung-nan-18m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC39A8 GHRHR FAT2 SLC15A1 SLC15A2

5.85e-05189975ca657353f2b649530809c0bc057e448adc511ec1
ToppCelldroplet-Lung-nan-18m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC39A8 GHRHR FAT2 SLC15A1 SLC15A2

5.85e-05189975e5325f1c7430b574947f8ee67e425455b60dc518
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

ADGRV1 CELSR1 SLC15A2 FARP1 SEL1L3

5.99e-05190975756bff697d30aec56c0ebfca94295f084a15bf37
ToppCelldroplet-Trachea-3m-Epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASSF7 CELSR1 FAT2 SLC15A2 PROM2

5.99e-051909750114cf48612d78c3ada4d8a05850501fef6892c5
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GALR1 CHST9 ADGRV1 TMEM196 NALCN

5.99e-051909752375e604eacd38f61f3e661ba2f76d286fcceca7
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASSF7 CELSR1 FAT2 SLC15A2 PROM2

5.99e-0519097501e7747547ea1f3049a11a1717565ba71dd52bdc
ToppCelldroplet-Trachea-nan-3m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASSF7 CELSR1 FAT2 SLC15A2 PROM2

5.99e-05190975e647f9a2dcf7f2dffef53c45bbe171416518fd59
ToppCellCOVID_vent-Lymphocytic-B_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

CD52 ABCB4 CELSR1 SLC15A2 SEL1L3

5.99e-0519097540b5e9e8f8fd8d84cb5b43e67b49267082348e9f
ToppCellCOVID_vent-Lymphocytic-B_cell-|COVID_vent / Disease condition, Lineage, Cell class and subclass

CD52 ABCB4 CELSR1 SLC15A2 SEL1L3

5.99e-05190975a37a32dc1b931562a6660074e19d5598efc65284
ToppCelldroplet-Trachea-nan-3m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASSF7 CELSR1 FAT2 SLC15A2 PROM2

5.99e-05190975434de72dde09644efbddcaa643a4a3eaf5f643bf
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FPR1 SLC39A8 P2RX7 ATP13A3 ATP2B1

6.15e-051919750b296404ebad0aadb75737f8c0462ec6934fc8bb
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

ADGRV1 ADCY8 SLC39A8 ITPR3 SCN1A

6.30e-0519297558c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CHST9 ADGRV1 ADCY8 SCN1A SEL1L3

6.30e-05192975b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MFSD6L ADGRV1 RASSF7 ADCY8 SEL1L3

6.30e-051929758898332387e5d746feb346ce1dabd6b2218fc6e5
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CHST9 ADGRV1 CELSR1 TMEM62 SEL1L3

6.30e-051929751aa5e4d9b32013a3f272561dcb8377f6805706df
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC39A8 ABCB1 SLC15A2 FARP1 SEL1L3

6.46e-05193975ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC39A8 CELSR1 TRAM1 ATP13A3 ATP2B1

6.46e-05193975b93f6af5999ad207fef5edc2bd900c7c6342f626
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CHST9 ADGRV1 RASSF7 ITPR3 SEL1L3

6.46e-051939755f0eba7b1440beb891d94a288f7f18a4e13c3a88
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADGRV1 RASSF7 ADCY8 SCN1A SEL1L3

6.46e-051939754b8202fcfe639a73f69a13f48fc3601ade256346
ToppCellfacs-Trachea-nan-3m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 FAT2 SLC15A2 SLC26A7 PROM2

6.61e-051949753701ca87c6dc9ccd7b4146e56371546174d26c36
ToppCellfacs-Trachea-nan-3m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 FAT2 SLC15A2 SLC26A7 PROM2

6.61e-0519497565f9bf126be26114c2c3f4c46d48318986212a92
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GALR1 CHST9 ADGRV1 TMEM196 CELSR1

6.61e-05194975b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CHST9 ADGRV1 RASSF7 ITPR3 SEL1L3

6.78e-05195975b78db0d929be6b04055805ea5ffecc56c47ba956
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGRV1 CELSR1 PROM2 FARP1 SEL1L3

6.78e-05195975dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CACNA1F ADGRV1 SLC39A8 CELSR1 SLC15A2

7.11e-05197975b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellControl_saline-Epithelial_alveolar-AT_2-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

ADGRV1 SLC13A2 SLC39A8 CELSR1 SLC15A2

7.11e-0519797544a59dfb889577b3160a5b13ada1276771a00241
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLC13A2 PLXNB2 SLC39A8 CELSR1 SCN1A

7.11e-051979751485933986921ff45669d9b7501c8d17050b3e97
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CHST9 FAT2 SLC15A2 PROM2 SCN8A

7.28e-0519897528ada093cec552262731194a04a4b9ff93186c3b
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

MICAL1 FLVCR2 CELSR1 SLC15A2 FARP1

7.28e-0519897585f424cd9bb3117c9e322031024aabb87696ce47
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRV1 SLC39A8 CELSR1 FARP1 SCN1A

7.46e-051999755f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CACNA1F FLVCR2 CELSR1 SLC15A2 FARP1

7.46e-05199975d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellBiopsy_Control_(H.)-Epithelial-MUC5AC+_High|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

MFSD6L CHST9 SLC13A2 FAT2 SLC15A2

7.46e-05199975a5240868cea40574ed4ee45eb27a00c1812957ed
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CACNA1F FLVCR2 CELSR1 SLC15A2 FARP1

7.64e-05200975ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CHST9 ADGRV1 CELSR1 FARP1 SLC25A29

7.64e-05200975d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRV1 SLC13A2 ADCY8 FARP1 SLC25A29

7.64e-052009757c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCellsevere-Myeloid-CD14_Monocytes_2|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

AGPAT3 FLVCR2 SLC39A8 P2RX7 CX3CR1

7.64e-0520097527d51fefe914b90e0a16498c43607d52fd38f53c
ToppCellControl-Epithelial_alveolar-Mes-Like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1F HSF2BP OTOP3 SLC15A2

1.21e-04116974df7609503782d8d7e4f31ed2a626916e5474d5bc
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Mgp|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

HSF2BP FAT2 SLC26A7 SLC47A1

1.56e-04124974b0ed84522180f8cea541461faf7882c57abf8cd4
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

HSF2BP FAT2 SLC26A7 SLC47A1

1.56e-04124974231862f849d8ab73c6a44c782d33ef2f07661baf
ToppCellControl-PLT_5|World / Disease Group and Platelet Clusters

ADCY8 FAT2 SLC15A1 SCN7A

1.66e-041269744ba753c4e83eb1d41964edfa22135e047f06c481
ToppCellControl-Epithelial_alveolar-Mes-Like-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1F HSF2BP AIFM2 SLC15A2

1.71e-04127974556aaf88719c83f307fa50dfac151136ed05c8ad
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC39A8 CELSR1 MTNR1A SLC7A10

2.04e-041339745bf5e654653e2c340891f51e3f2a30441b7b6b2b
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Sphkap-Excitatory_Neuron.Gad1Gad2.Sphkap-Cpne4_(Basomedial_amygdaloid_nucleus_(BMA))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CHST9 MTNR1A SCN10A

2.22e-04549737670a6eb185ae0d8c3c0cb17f8eaa9970355187b
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Sphkap-Excitatory_Neuron.Gad1Gad2.Sphkap-Cpne4_(Basomedial_amygdaloid_nucleus_(BMA))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CHST9 MTNR1A SCN10A

2.22e-045497379f804e73f859c0e8192d9e9e6ee2282f7f1691b
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ADCY8 FAT2 SLC15A1 SCN7A

2.23e-0413697427a41463e6f16deb5b1d4f17fefded9959038c07
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY8 SLC39A8 GHRHR SEL1L3

2.23e-0413697482b1d6d839c0d0c68e0960549f688138479defcc
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADCY8 FAT2 SLC15A1 SCN7A

2.23e-0413697488b5c839d0446c6d6b7e81fc4d48f5e7e96eea11
ToppCell356C-Epithelial_cells-Epithelial-B_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SLC39A8 AIFM2 SCN8A TAS2R43

2.42e-04139974aefcfda2b2db302ce4b3d2a09f767be0b1c3ac6c
ToppCell356C-Epithelial_cells-Epithelial-B_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SLC39A8 AIFM2 SCN8A TAS2R43

2.42e-04139974b9c2dfab119ac0efdf931bb2910e82bccdb4e48d
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Sphkap|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CHST9 MTNR1A SCN10A

2.48e-0456973af55596513ddbe60b08648b27e41a7b65e3da58c
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 SCN1A SCN10A OPN5

2.84e-0414597496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Akr1c18_Ntf3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MATN2 SLC39A8 AIFM2 GPR176

3.15e-041499741e77f03d2b32f366018fec3462d1b75f6e7febb9
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

HSF2BP FAT2 SLC26A7 SLC47A1

3.48e-04153974151c469b26f9adf04dd6f117f03bef760cc3d45d
Drugsodium

SLC12A6 NR2C2 SLC2A7 SLC19A2 SLC13A2 SLC1A6 ADCY8 P2RX7 SLC15A1 SLC15A2 SLC26A7 SCN4A SCN7A SCN10A SLC47A1 ATP2B1 SLC7A10 ATP2B4

1.00e-079449818CID000000923
Drugprobenecid

SLC22A11 SLC22A7 ADCY8 ABCB1 ABCB4 SLC22A9 SLC47A1

1.04e-06123987CID000004911
DrugAPETx1, Anthopleura elegantissima

SCN4A SCN8A SCN10A

1.53e-066983ctd:C475726
DrugAC1NSKPI

ABCB1 ABCB4 P2RX7 ATP2B1 ATP2B4

4.67e-0657985CID005311482
Drugmethylglucamine

P2RX7 SCN4A SCN8A ATP2B1 ATP2B4

7.10e-0662985CID000004049
DrugAC1L1E7E

SLC15A1 SLC15A2 SLC47A1

9.08e-0610983CID000002673
DrugAC1O46SI

FPR1 SLC15A1 SLC15A2

9.08e-0610983CID006400580
Druglamotrigine

CACNA1F ABCB1 ITPR3 SCN4A SCN7A SCN10A

1.10e-05116986CID000003878
Drugstrontium

ITPR3 P2RX7 SLC41A1 ATP2B1 ATP2B4

1.12e-0568985CID000104798
DrugNSC 117356

CD52 SLC22A11 SLC19A2 SLC22A7 ABCB1 ABCB4 SLC22A9 POLR3B

1.13e-05246988CID000004112
Drugcimetidine

SLC22A11 SLC22A7 ADCY8 ABCB1 ABCB4 SLC22A9 SLC47A1

1.25e-05179987CID000002756
Drug5-hydroxypropafenone

ABCB1 SCN4A SCN7A SCN10A

1.36e-0534984CID000107927
Drugfluo-3

SLC22A7 ABCB1 ITPR3 P2RX7 ATP2B1 ATP2B4

1.47e-05122986CID000104978
Drugbepridil

CACNA1F ITPR3 SCN4A SCN7A SCN10A ATP2B1

1.77e-05126986CID000002351
Drugmoexipril

SLC15A1 SLC15A2

1.83e-052982ctd:C058302
Drug1,9-dideoxyforskolin

ABCB1 ABCB4

1.83e-052982ctd:C047983
Drug4-methylumbelliferyl sulfate

SLC22A11 SLC22A9

1.83e-052982ctd:C019492
Drugnaphthyl sulfate

SLC22A11 SLC22A9

1.83e-052982ctd:C029092
Drugglycylsarcosine

SLC15A1 SLC15A2

1.83e-052982ctd:C004194
Drugcaloxin 1b1

ATP2B1 ATP2B4

1.83e-052982ctd:C510327
Drugquinaprilat

SLC15A1 SLC15A2

1.83e-052982ctd:C054501
Drugdihydropyridine

CACNA1F SLC22A7 ABCB1 ITPR3 SCN4A ATP2B1 ATP2B4

2.04e-05193987CID000104822
DrugChlorine

NR2C2 GALR1 SLC1A6 ADCY8 ABCB1 ITPR3 SLC15A1 SCN4A MTNR1A

2.97e-05367989ctd:D002713
Drugbumetanide

SLC12A6 SLC13A2 SLC1A6 SLC22A7 SLC15A1 SLC15A2 SLC26A7

3.39e-05209987CID000002471
Drugsulfinpyrazone

SLC22A11 SLC22A7 ABCB1 ABCB4 SLC22A9

3.73e-0587985CID000005342
DrugBumetanide

SLC12A6 SLC22A11 SLC22A7

4.16e-0516983ctd:D002034
Drugphenytoin

CACNA1F PLXNB2 ABCB1 ITPR3 SCN4A SCN7A SCN10A

4.56e-05219987CID000001775
DrugBay K 8644

CACNA1F ADCY8 ITPR3 SLC25A29 ATP2B1 ATP2B4

4.73e-05150986CID000002303
Drugverapamil

CACNA1F ADCY8 ABCB1 ABCB4 ITPR3 SCN4A SCN7A SCN10A ATP2B1 ATP2B4

5.02e-054909810CID000002520
Drugspirapril

SLC15A1 SLC15A2

5.49e-053982ctd:C052555
DrugTechnetium Tc 99m Sestamibi

ABCB1 ABCB4

5.49e-053982ctd:D017256
Drugnitrendipine

CACNA1F ADCY8 ABCB1 ITPR3 SLC25A29

6.60e-0598985CID000004507
Drug2-(aminomethyl)pyrrolidine

FPR1 ADCY8 ITPR3 P2RX7 ATP2B1 ATP2B4

7.01e-05161986CID000072032
Drugtetraphenylphosphonium

ABCB1 ABCB4 SLC47A1

7.13e-0519983CID000164911
Drugdiprafenone

SCN4A SCN7A SCN10A

7.13e-0519983CID000071249
Drugisradipine

CACNA1F ITPR3 SCN4A SCN7A SCN10A

7.26e-05100985CID000003784
Drugtetraethylammonium

SLC22A11 SLC22A7 ABCB1 SLC22A9 SLC15A2 SCN4A SLC47A1

7.31e-05236987CID000005413
DrugSoybean Oil

SLC22A7 ABCB1 ABCB4

8.36e-0520983ctd:D013024
Drugsulfobromophthalein

SLC22A11 SLC22A7 ABCB1 ABCB4 SLC22A9

8.36e-05103985CID000005345
DrugUTP-NA

GALR1 FPR1 PFKM ADCY8 ITPR3 POLR3B P2RX7 ATP2B1 ATP2B4

8.39e-05420989CID000001181
Druggabapentin

CACNA1F ABCB1 ITPR3 SCN4A SCN7A SCN10A

9.16e-05169986CID000003446
Drugpotassium

SLC12A6 CACNA1F GALR1 SLC1A6 ADCY8 ITPR3 P2RX7 SCN4A SCN7A SCN10A ATP2B1 SLC7A10 ATP2B4 CX3CR1

1.03e-0410089814CID000000813
Drugdimethylaminobenzoate

ABCB1 ABCB4

1.09e-044982CID012241998
DrugAPETx2 protein, Anthopleura elegantissima

SCN8A SCN10A

1.09e-044982ctd:C501880
Drugcinchonine

ABCB1 SLC47A1

1.09e-044982ctd:C010086
Drugcarbamazepine

SLC13A2 ADCY8 ABCB1 SCN4A SCN7A SCN10A

1.26e-04179986CID000002554
Drugestrone sulfate

SLC22A11 SLC22A7 SLC22A9

1.29e-0423983ctd:C017296
DrugNSC7524

CACNA1F ADCY8 ITPR3 SCN4A SCN7A SCN10A

1.38e-04182986CID000005657
DrugAC1NT1AF

SCN4A SCN7A SCN10A

1.66e-0425983CID005322157
DrugAC1L1CQC

ABCB1 SCN4A SCN7A SCN10A

1.79e-0465984CID000002012
DrugAC1L2MCS

ABCB1 ABCB4

1.82e-045982CID000023441
DrugGlutarates

SLC22A7 SLC22A9

1.82e-045982ctd:D005977
DrugPirmenolum

SCN4A SCN7A SCN10A

1.87e-0426983CID000004853
Drugresiniferatoxin

ABCB1 SCN4A SCN7A SCN10A

1.90e-0466984CID000104826
Drugacyclovir

FPR1 ADCY8 SLC15A1 SLC15A2 SLC47A1

2.00e-04124985CID000002022
DrugPbTx-1

SCN4A SCN7A SCN10A

2.10e-0427983CID006437089
DrugSulfobromophthalein

SLC22A11 SLC22A7 ABCB4

2.10e-0427983ctd:D013448
DrugAC1L1MOZ

SCN4A SCN7A SCN10A

2.10e-0427983CID000031958
Drugnefopam

SCN4A SCN7A SCN10A

2.10e-0427983CID000004450
DrugPregnenolone [145-13-1]; Up 200; 12.6uM; PC3; HT_HG-U133A

CD52 SLC1A6 SLC22A7 GHRHR MTNR1A SCN10A

2.17e-041989864218_UP
Drugprochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HG-U133A

NR2C2 FLVCR2 SLC22A7 EFR3A GHRHR SLC15A2

2.23e-04199986455_DN
Drugparaben

SCN4A SCN7A SCN10A

2.34e-0428983CID000007175
DrugAC1L1E6T

SLC15A1 SLC15A2 SLC47A1

2.34e-0428983CID000002666
DrugDehydroepiandrosterone Sulfate

SLC22A11 SLC22A7 SLC22A9

2.60e-0429983ctd:D019314
DrugAC1L1TSE

ABCB1 ABCB4 P2RX7 SLC15A1

2.65e-0472984CID000060719
DrugPIHCA

ABCB1 ABCB4

2.72e-046982CID000108097
Drugv 104

ABCB1 ABCB4

2.72e-046982CID000107262
DrugAC1L99H3

ABCB1 ABCB4

2.72e-046982CID000440540
Drugtocainide

SCN4A SCN7A SCN10A

2.89e-0430983CID000038945
Drug1, 3-diallylurea

ABCB1 SCN4A SCN7A SCN10A

2.95e-0474984CID000074537
Drugsodium bicarbonate

NR2C2 ADGRV1 ADCY8 SLC25A29

2.95e-0474984CID000010340
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN4A SCN7A SCN8A SCN10A

5.87e-1110905DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN4A SCN7A SCN8A SCN10A

5.87e-1110905DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN4A SCN7A SCN8A SCN10A

1.84e-1012905DOID:0060170 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SLC12A6 SLC13A2 SLC1A6 ABCB1 SCN1A SCN4A SCN7A SCN8A SCN10A

1.85e-09163909DOID:1826 (implicated_via_orthology)
DiseaseCharcot-Marie-Tooth disease (is_implicated_in)

SLC12A6 ITPR3 POLR3B

5.92e-0612903DOID:10595 (is_implicated_in)
Diseasesensory perception of bitter taste

TAS2R14 TSPAN14 TAS2R19

6.78e-0526903GO_0050913
DiseaseHailey-Hailey disease (implicated_via_orthology)

ATP2B1 ATP2B4

1.37e-046902DOID:0050429 (implicated_via_orthology)
Diseasegallbladder neoplasm

ABCB1 ABCB4

3.27e-049902EFO_0004606
Diseasecystic fibrosis (implicated_via_orthology)

ABCB1 ABCB4

3.27e-049902DOID:1485 (implicated_via_orthology)
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

ADGRV1 SCN1A

3.27e-049902C3502809
DiseaseIntrahepatic cholestasis of pregnancy

ABCB1 ABCB4

1.07e-0316902EFO_0009048
DiseaseDrug-induced agranulocytosis

SCN8A TMEM26

1.07e-0316902HP_0012235
Diseasetheta wave measurement

GALR1 SLC39A8

1.21e-0317902EFO_0006873
DiseaseAlzheimer disease, brain volume measurement

ADCY8 FARP1

1.21e-0317902EFO_0006930, MONDO_0004975
DiseaseEpilepsy, Cryptogenic

ABCB1 SCN1A SCN8A

2.04e-0382903C0086237
DiseaseAwakening Epilepsy

ABCB1 SCN1A SCN8A

2.04e-0382903C0751111
DiseaseAura

ABCB1 SCN1A SCN8A

2.04e-0382903C0236018
Diseasethalamus volume

ADGRV1 SLC39A8 OR2A12

2.26e-0385903EFO_0006935
Diseasevisuospatial function measurement

FARP1 GPR176

2.85e-0326902EFO_0803533
Diseasepseudotumor cerebri

TAS2R14 TAS2R43

2.85e-0326902EFO_1001132

Protein segments in the cluster

PeptideGeneStartEntry
HFLQGSITFIIGILQ

TMEM62

521

Q0P6H9
SITFIIGILQLAFFN

TMEM62

526

Q0P6H9
NVIIFASILINFLGA

ADCY8

786

P40145
QAFSLGIGICFIELQ

ARAP3

426

Q8WWN8
IIGVGLLQIFQGHFE

SLC7A10

201

Q9NS82
LSQIIICIGFQSLGF

ATP13A3

1011

Q9H7F0
ITNFTILRQQGVFGD

ADGRV1

1266

Q8WXG9
IFAIGLVGNLLVVFA

CX3CR1

41

P49238
LFLSQLVFVIGINQT

CELSR1

2511

Q9NYQ6
KIVQNAIIQTIGFFG

EFR3A

376

Q14156
EGIFNNAIFCTIVLG

ATP2B1

1001

P20020
VLGTFICQIFIVEFG

ATP2B4

1001

P23634
ALAQAIGQTGRFVLV

RASSF7

36

Q02833
LTIVISGHFFIFQGQ

REC114

66

Q7Z4M0
NITEELFFTGLIGNV

NR2C2

556

P49116
TNKIVFVVSFVGNRG

ITPR3

2291

Q14573
FVVGVFCAIINGGLQ

ABCB1

711

P08183
VIFGSFFVLNLVLGV

CACNA1F

356

O60840
IFVGFVIITFRAQGE

CACNA1F

1131

O60840
AGQLFSGLLALNVVF

OTOP3

86

Q7RTS5
QGNQTTITEFILLGF

OR1S1

16

Q8NH92
TRLNQVVLFAGSAFI

OR2A12

191

Q8NGT7
LFIRQGTGLQGQAVF

LEO1

471

Q8WVC0
AIGNVLFVAGLAFVI

GOLT1B

36

Q9Y3E0
IFAIGVGQVDFNTLK

MATN2

191

O00339
TVQVVIFIGSLLGNF

GPR176

46

Q14439
VIVGVFLAQIFSLQA

SLC2A7

176

Q6PXP3
GAFVGASLLFLLVNV

GPR137

141

Q96N19
LIDSVLQGFNGTVFA

KIF3C

81

O14782
VLVGAIVSTVQNFLF

MFSD6L

376

Q8IWD5
INVTGQGFSLIQRFA

PLXNB2

1001

O15031
GFFNINALLGIITLA

FAT2

1601

Q9NYQ8
LGFVHGGIQTLFIAQ

OR4C45

146

A6NMZ5
AQIGIVAVVRGSLFF

OR51E2

141

Q9H255
TKFNIQGLVIIGGFE

PFKM

486

P08237
QASVGGQVFILNILF

OPN5

191

Q6U736
LAIGITANFVNGRTV

MICAL1

236

Q8TDZ2
AQNIANLGTGIIISF

ABCB4

836

P21439
GFGNSFVQVVLTVQL

OR2B11

156

Q5JQS5
QVVFVGNFLRINTIA

PANK2

516

Q9BZ23
VFGTGGKFDIIQLVV

P2RX7

321

Q99572
LFGIGVENFVTLVVF

GALR1

26

P47211
NLAVANTGILVFQGF

FARP1

241

Q9Y4F1
ISGGIFLFFVANAII

CD52

41

P31358
INALGLVVFSVAFGL

SLC1A6

266

P48664
TGFIGLEVVAQLFNC

ATL3

461

Q6DD88
FIPIGIGIFVTSNNI

TMEM30A

61

Q9NV96
LLNISAQVFGIIFTI

FLVCR2

441

Q9UPI3
AQVFGIIFTISQGQI

FLVCR2

446

Q9UPI3
LSVGVNFGLFLNIIR

GHRHR

291

Q02643
FINALVFGVQGNTLR

SLC25A29

71

Q8N8R3
IQVVIVFAGFLLQGA

GPR142

206

Q7Z601
VFAGFLLQGAVLARQ

GPR142

211

Q7Z601
ALVFFVIFLIVQTGN

LSMEM1

76

Q8N8F7
LGLNVYQTQLLFGAV

SLC22A7

371

Q9Y694
GGVGLFQTLQVLTFI

SLC22A11

11

Q9NSA0
VVGTAGVLQAFAIVL

SLC12A6

211

Q9UHW9
SNLLFFGGLLVAIAV

SLC13A2

86

Q13183
IIVLIVAGAGQFSKQ

SLC15A1

631

P46059
GNIIVLVVAQFSGLV

SLC15A2

656

Q16348
ALVFGVNTFIALALQ

SLC19A2

421

O60779
IFGAQFVLTVIQAIG

SCAMP4

111

Q969E2
FVLIVEFIIGNLGNS

TAS2R14

11

Q9NYV8
EFIIGNLGNSFIALV

TAS2R14

16

Q9NYV8
ILVVFAFVLGNVANG

TAS2R19

11

P59542
AFVLGNVANGFIALV

TAS2R19

16

P59542
ILVVVAFILGNFANG

TAS2R20

11

P59543
ILIVVIFVIGNFANG

TAS2R30

11

P59541
IFVIGNFANGFIALV

TAS2R30

16

P59541
SVVVVLFVIGNFANG

TAS2R31

11

P59538
LFVIGNFANGFIALV

TAS2R31

16

P59538
ILVVFAFVLGNFSNG

TAS2R33

11

P0DSN6
ILVVFAFVLGNFSNG

TAS2R36

11

P0DTE0
SLVVVTFVIGNFANG

TAS2R43

11

P59537
TFVIGNFANGFIALV

TAS2R43

16

P59537
ILVVVTFVIGNFANG

TAS2R45

11

P59539
TFVIGNFANGFIALV

TAS2R45

16

P59539
ILIVVTFVIGNFANG

TAS2R46

11

P59540
TFVIGNFANGFIALV

TAS2R46

16

P59540
LFVLGNFANGFIALV

TAS2R50

16

P59544
QFVFALAGIVTNVAA

HSF2BP

181

O75031
AALQGFQTQVLGFIE

TRIM47

276

Q96LD4
FRLDISFNGGQIVVT

SEL1L3

356

Q68CR1
NIGISVFIQDGPFLV

TMEM26

256

Q6ZUK4
FDNVLTVGNLVFTGI

SCN4A

606

P35499
FGSFLGIIGINLVEN

TMEM255B

66

Q8WV15
VTFKDNFRQGLVVGI

AIFM2

71

Q9BRQ8
GNNVFLLQTLFGAVI

SLC22A9

376

Q8IVM8
LVFAVTFVLGVLGNG

FPR1

31

P21462
ALIQVQATVVGFLAS

SLC41A1

181

Q8IVJ1
TVFQAVCFLGFIIQL

SLC47A1

446

Q96FL8
FNNVLTVGNLVFTGI

SCN1A

796

P35498
KQVFLSVLIFGVAGL

CHST9

11

Q7L1S5
LIGGILNFQFLRAVT

TMEM196

86

Q5HYL7
LAGSNIFTIGVQDFV

TRAPPC11

571

Q7Z392
LVGFVFVVSGLVINF

AGPAT3

16

Q9NRZ7
FVVSGLVINFVQLCT

AGPAT3

21

Q9NRZ7
LVFATFLVGGNVQTL

PROM2

491

Q8N271
GFFTLNLFVGVIIDN

SCN10A

1406

Q9Y5Y9
FEHVLAVGNLVFTGI

SCN8A

781

Q9UQD0
VFLVFLNGNILGVIR

POLR3B

536

Q9NW08
FSTGNFNVLAVRIAV

TRAM1

286

Q15629
VGLAIGTLFSNAIFQ

SLC39A8

166

Q9C0K1
LLNIGNLVFIGIFTA

SCN7A

536

Q01118
VAGVFIAISLLQIFG

TSPAN14

236

Q8NG11
FVAQVLVGKFTEGNI

ZC3HAV1

841

Q7Z2W4
FAANVGLLFGVVCTI

SLC26A7

451

Q8TE54
IGINFGLLTSEVFQV

TSPAN19

216

P0C672
LKNISIAFTGVVGFL

SLC36A4

451

Q6YBV0
DPTLFQVVVGILGNF

VN1R2

91

Q8NFZ6
VIGSIFNITGIAINR

MTNR1A

111

P48039
IGLTLFVGVVIANFN

NALCN

1146

Q8IZF0