Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionzinc ion binding

ZMYND11 THRA PPARD KDM4C ZKSCAN5 TRIM51G TET1 PML

1.16e-05891268GO:0008270
GeneOntologyMolecularFunctiontransition metal ion binding

ZMYND11 THRA PPARD KDM4C ZKSCAN5 TRIM51G TET1 PML

9.18e-051189268GO:0046914
GeneOntologyMolecularFunctionmodification-dependent protein binding

UIMC1 ZMYND11 KDM4C PML

1.38e-04206264GO:0140030
GeneOntologyMolecularFunctionubiquitin-like protein reader activity

UIMC1 PML

4.80e-0425262GO:0140035
GeneOntologyMolecularFunctionnuclear receptor activity

THRA PPARD

2.75e-0360262GO:0004879
GeneOntologyMolecularFunctionligand-activated transcription factor activity

THRA PPARD

2.85e-0361262GO:0098531
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

KDM4C TET1

3.22e-0365262GO:0016706
GeneOntologyBiologicalProcessprotein-DNA complex organization

UIMC1 ZMYND11 THRA BRCA2 KDM4C MOS TET1 PML

1.52e-05999258GO:0071824
GeneOntologyBiologicalProcessnegative regulation of cell cycle phase transition

UIMC1 BRCA2 CTDSPL MOS PML

3.13e-05311255GO:1901988
GeneOntologyBiologicalProcessnegative regulation of cell cycle process

UIMC1 BRCA2 CTDSPL MOS PML

6.44e-05362255GO:0010948
GeneOntologyBiologicalProcesschromatin organization

UIMC1 ZMYND11 BRCA2 KDM4C MOS TET1 PML

6.89e-05896257GO:0006325
GeneOntologyBiologicalProcesscell cycle phase transition

UIMC1 BRCA2 CCNB3 CTDSPL MOS PML

8.33e-05627256GO:0044770
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

THRA PPARD KDM4C PML

1.99e-04244254GO:0009755
GeneOntologyBiologicalProcessnegative regulation of cell cycle

UIMC1 BRCA2 CTDSPL MOS PML

2.06e-04464255GO:0045786
GeneOntologyBiologicalProcessregulation of cell cycle phase transition

UIMC1 BRCA2 CTDSPL MOS PML

3.37e-04516255GO:1901987
GeneOntologyCellularComponentsynaptonemal structure

HORMAD2 BRCA2

1.49e-0346262GO:0099086
GeneOntologyCellularComponentsynaptonemal complex

HORMAD2 BRCA2

1.49e-0346262GO:0000795
MousePhenoabnormal cell cycle

UIMC1 HORMAD2 HMMR BRCA2 CCNB3 MOS TET1 PML

4.61e-07520218MP:0003077
MousePhenoincreased classified tumor incidence

UIMC1 SRPX PPARD BRCA2 MOS TET1 PML

8.84e-07381217MP:0010273
MousePhenoabnormal classified tumor incidence

UIMC1 SRPX PPARD BRCA2 MOS TET1 PML

9.32e-07384217MP:0020188
MousePhenoincreased T cell derived lymphoma incidence

UIMC1 SRPX BRCA2 PML

1.05e-0653214MP:0002024
MousePhenoincreased thymus tumor incidence

UIMC1 SRPX BRCA2 PML

1.13e-0654214MP:0010365
MousePhenoincreased gland tumor incidence

UIMC1 SRPX PPARD BRCA2 PML

1.62e-06139215MP:0010288
MousePhenoabnormal tumor incidence

UIMC1 SRPX PPARD BRCA2 KDM4C MOS TET1 PML

2.09e-06635218MP:0002019
MousePhenoabnormal tumor susceptibility

UIMC1 SRPX PPARD BRCA2 KDM4C MOS TET1 PML

2.49e-06650218MP:0002166
MousePhenoabnormal female meiosis

HORMAD2 CCNB3 MOS TET1

6.72e-0684214MP:0005168
MousePhenoabnormal oogenesis

HORMAD2 HMMR CCNB3 MOS TET1

6.76e-06186215MP:0001931
MousePhenoneoplasm

UIMC1 SRPX PPARD BRCA2 KDM4C MOS TET1 PML

7.00e-06747218MP:0002006
MousePhenoincreased tumor incidence

UIMC1 SRPX PPARD BRCA2 MOS TET1 PML

7.92e-06530217MP:0002020
MousePhenoabnormal meiosis

HORMAD2 HMMR CCNB3 MOS TET1

2.37e-05241215MP:0001930
MousePhenoabnormal polar body morphology

CCNB3 MOS

3.21e-056212MP:0012736
MousePhenoabnormal DNA repair

UIMC1 BRCA2 TET1 PML

3.78e-05130214MP:0008058
MousePhenoabnormal female germ cell morphology

HMMR CCNB3 MOS TET1

6.61e-05150214MP:0006361
MousePhenoincreased lymphoma incidence

UIMC1 SRPX BRCA2 PML

9.35e-05164214MP:0012431
MousePhenoabnormal meiotic spindle morphology

HMMR MOS

1.17e-0411212MP:0009761
MousePhenoabnormal double-strand DNA break repair

BRCA2 TET1 PML

1.50e-0470213MP:0010948
MousePhenoincreased hemolymphoid system tumor incidence

UIMC1 SRPX BRCA2 PML

1.68e-04191214MP:0010296
MousePhenoincreased circulating thyroxine level

ZMYND11 THRA

2.23e-0415212MP:0005477
MousePhenoincreased organ/body region tumor incidence

UIMC1 SRPX PPARD BRCA2 PML

2.46e-04395215MP:0010274
MousePhenoincreased thyroxine level

ZMYND11 THRA

2.55e-0416212MP:0005470
MousePhenoabnormal organ/body region tumor incidence

UIMC1 SRPX PPARD BRCA2 PML

2.64e-04401215MP:0013152
MousePhenoabnormal germ cell morphology

HORMAD2 HMMR BRCA2 CCNB3 CCDC136 MOS TET1

3.19e-04946217MP:0002208
MousePhenoabnormal compact bone volume

THRA PPARD

3.24e-0418212MP:0010963
MousePhenoabnormal foam cell morphology

HORMAD2 HMMR BRCA2 CCNB3 CCDC136 MOS TET1

3.36e-04954217MP:0009840
MousePhenoincreased circulating levels of thyroid hormone

ZMYND11 THRA

3.62e-0419212MP:0003350
MousePhenoabnormal ovary morphology

ZMYND11 HMMR BRCA2 MOS TET1

4.53e-04451215MP:0001126
MousePhenoabnormal female reproductive gland morphology

ZMYND11 HMMR BRCA2 MOS TET1

5.75e-04475215MP:0013324
MousePhenoabnormal incidence of induced tumors

UIMC1 PPARD BRCA2 KDM4C

6.20e-04269214MP:0013151
MousePhenoabnormal fibroblast physiology

UIMC1 BRCA2 ARPC3 PML

6.37e-04271214MP:0020414
MousePhenoabnormal gametogenesis

HORMAD2 HMMR BRCA2 CCNB3 CCDC136 MOS TET1

6.75e-041070217MP:0001929
MousePhenoabnormal cell differentiation

HORMAD2 HMMR PPARD CCNB3 MOS TET1

8.62e-04795216MP:0005076
MousePhenoabnormal intracellular organelle physiology

UIMC1 THRA BRCA2 TET1 PML

9.60e-04532215MP:0014241
MousePhenoabnormal endocrine gland morphology

UIMC1 HORMAD2 ZMYND11 SRPX THRA BRCA2 PML

1.01e-031144217MP:0013560
MousePhenoabnormal female reproductive system physiology

HMMR THRA BRCA2 CCNB3 MOS TET1

1.43e-03876216MP:0003699
MousePhenoabnormal metabolism

UIMC1 THRA PPARD BRCA2 TET1 PML

2.01e-03936216MP:0005266
Domainzf-C4

THRA PPARD

1.58e-0346242PF00105
DomainNUCLEAR_REC_DBD_1

THRA PPARD

1.58e-0346242PS00031
DomainZnf_hrmn_rcpt

THRA PPARD

1.58e-0346242IPR001628
DomainNuclear_hrmn_rcpt

THRA PPARD

1.58e-0346242IPR001723
DomainZnF_C4

THRA PPARD

1.58e-0346242SM00399
DomainNUCLEAR_REC_DBD_2

THRA PPARD

1.58e-0346242PS51030
Domain-

THRA PPARD

1.65e-03472421.10.565.10
DomainHOLI

THRA PPARD

1.72e-0348242SM00430
DomainNucl_hrmn_rcpt_lig-bd

THRA PPARD

1.72e-0348242IPR000536
DomainHormone_recep

THRA PPARD

1.72e-0348242PF00104
Domain-

THRA PPARD

2.42e-03572423.30.50.10
DomainZnf_NHR/GATA

THRA PPARD

2.50e-0358242IPR013088
DomainTSP_1

RSPO3 ADAMTSL1

2.95e-0363242PF00090
DomainTSP1

RSPO3 ADAMTSL1

3.13e-0365242SM00209
DomainTSP1_rpt

RSPO3 ADAMTSL1

3.13e-0365242IPR000884
DomainTSP1

RSPO3 ADAMTSL1

3.13e-0365242PS50092
DomainPHD

ZMYND11 KDM4C

5.79e-0389242SM00249
DomainZnf_PHD

ZMYND11 KDM4C

6.04e-0391242IPR001965
DomainZF_PHD_2

ZMYND11 KDM4C

6.57e-0395242PS50016
DomainZF_PHD_1

ZMYND11 KDM4C

6.70e-0396242PS01359
DomainZnf_FYVE_PHD

ZMYND11 KDM4C

1.52e-02147242IPR011011
Domain-

ZMYND11 KDM4C PML

1.92e-024492433.30.40.10
DomainZnf_RING/FYVE/PHD

ZMYND11 KDM4C PML

2.03e-02459243IPR013083
PathwayWP_DNA_IRDAMAGE_AND_CELLULAR_RESPONSE_VIA_ATR

UIMC1 BRCA2 PML

1.40e-0481183M39490
PathwayPID_RXR_VDR_PATHWAY

THRA PPARD

4.91e-0426182M162
PathwayWP_WNTBETACATENIN_SIGNALING_IN_LEUKEMIA

PPARD PML

4.91e-0426182M39407
Pubmed

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance.

PPARD PML

5.37e-07226222902876
Pubmed

Multiple roles of FOXJ3 in spermatogenesis: A lesson from Foxj3 conditional knockout mouse models.

HORMAD2 BRCA2 TET1

1.81e-063226327739607
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

ZMYND11 THRA PPARD BRCA2 KDM4C ZKSCAN5 PML

2.74e-0687726720211142
Pubmed

EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer.

ZMYND11 BRCA2

3.22e-06426214651845
Pubmed

Autologous K63 deubiquitylation within the BRCA1-A complex licenses DNA damage recognition.

UIMC1 BRCA2

5.37e-06526235938958
Pubmed

Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers.

HMMR BRCA2

8.05e-06626225830658
Pubmed

A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARalpha and T18 oncoproteins.

THRA PML

8.05e-06626210610177
Pubmed

SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice.

HORMAD2 BRCA2

1.50e-05826230393076
Pubmed

RNF168-mediated localization of BARD1 recruits the BRCA1-PALB2 complex to DNA damage.

UIMC1 BRCA2

1.50e-05826234408138
Pubmed

Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance.

UIMC1 BRCA2

1.93e-05926224085845
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZMYND11 THRA PPARD ZNF718 KDM4C PML

2.39e-0580826620412781
Pubmed

Expression of cellular oncogenes during embryonic and fetal development of the mouse.

THRA MOS

2.41e-05102626594688
Pubmed

TOPORS-mediated RAD51 SUMOylation facilitates homologous recombination repair.

BRCA2 PML

2.94e-051126235061896
Pubmed

The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair.

UIMC1 BRCA2

4.17e-051326229499138
Pubmed

Mitochondrial biogenesis and thyroid status maturation in brown fat require CCAAT/enhancer-binding protein alpha.

THRA PPARD

1.12e-042126211940593
Pubmed

BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer

HMMR BRCA2

1.12e-042126220301425
Pubmed

Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.

UIMC1 HMMR BRCA2

1.86e-0414926325184681
Pubmed

The human and mouse receptors for hyaluronan-mediated motility, RHAMM, genes (HMMR) map to human chromosome 5q33.2-qter and mouse chromosome 11.

HMMR THRA

1.86e-04272628595891
Pubmed

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

BRCA2 TET1

1.86e-042726223395962
Pubmed

Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.

UIMC1 PPARD BRCA2

2.75e-0417026319064572
Pubmed

Tet2- and Tet3- Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment.

RSPO3 TET1

2.80e-043326236522157
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

UIMC1 HMMR BRCA2 PML

3.14e-0444426434795231
Pubmed

HiPLA: High-throughput imaging proximity ligation assay.

BRCA2 PML

5.45e-044626230419336
Pubmed

Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice.

PPARD TET1

5.69e-044726232892421
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

FAM76B UIMC1 COIL BRCA2 PML

6.26e-0495426536373674
Pubmed

Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle.

RSPO3 PPARD

6.44e-045026227597886
Pubmed

CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins.

MOS TET1

7.23e-045326224357321
GeneFamilyNuclear hormone receptors

THRA PPARD

1.07e-034918271
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM51G PML

3.96e-039518259
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / Treatment groups by lineage, cell group, cell type

RSPO3 DEPDC1 HMMR BRCA2 CCNB3

9.34e-08197265038fd92750257d43d5e980fd06d77742b543f11a
ToppCellDividing_Macrophages-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

DEPDC1 HMMR BRCA2 ZNF718

3.09e-061752640a8bf455babb3271aa00642199fb58b0b02dc3ac
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DEPDC1 SRPX HMMR BRCA2

4.84e-06196264eb8c9a4a5eb21d43ff7b25deae5896c236f669b9
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DEPDC1 SRPX HMMR BRCA2

4.94e-0619726476b61e60a757e58b465569538e632d6d9953e89a
ToppCellSigmoid-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

DEPDC1 HMMR BRCA2 CCDC136

5.25e-062002644e489ecf472857357d45e9f6c7a812aa48b72ebf
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BRCA2 CCDC136 ASTE1

3.55e-05110263c80d1c3df75648e2c8f6832279c2acca63d76681
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BRCA2 CCNB3 STPG2

6.97e-05138263611fe0fb284e12678f9c47a0bdbfc367a93c52b3
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DEPDC1 HMMR STPG2

9.10e-05151263c06a54afe918b14f885d6a85fbcf81e80f33afae
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

9.84e-05155263969fc4c98a96bf2f436e8e63d4deb2183ef3b864
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.00e-04156263b3f10cd044f24807576e7d56e51df7064dbf6c50
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.02e-041572631ccb07a38d3fb606ee5fbc0437655f49baaaa62c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

HMMR CTDSPL TET1

1.04e-041582635775246e192629058ed89fb56031bdf4cbb9c15c
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DEPDC1 HMMR BRCA2

1.14e-041632635285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.14e-041632633f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.18e-04165263eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DEPDC1 ADAMTSL1 HMMR

1.18e-041652634297588f809e8a8275ab1a6ed99daac7ad93bd61
ToppCellDividing_Macrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

DEPDC1 HMMR BRCA2

1.20e-04166263c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.20e-041662632642544070564debe2deb2938d2c33997bf5ef02
ToppCell10x5'-Liver-Hematopoietic_progenitors|Liver / Manually curated celltypes from each tissue

DEPDC1 HMMR BRCA2

1.20e-04166263ae967570248cf86ca3ddf55e33bcbb3e4e3684bc
ToppCell10x5'-Liver-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Liver / Manually curated celltypes from each tissue

DEPDC1 HMMR BRCA2

1.20e-04166263a176e87aa6eec81d1fb79a028f759182d11b567d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.23e-0416726350c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_1|390C / Donor, Lineage, Cell class and subclass (all cells)

DEPDC1 HMMR BRCA2

1.25e-041682632082b15fc7935a211f1c61506b305af5501a21ad
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.25e-04168263d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellDividing_Macrophages-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

DEPDC1 HMMR BRCA2

1.27e-04169263eb0c993ef2eea73bc4881182520922ce9ae9368f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.27e-04169263e7514956b2e4298222ec443f98b2f5289451786e
ToppCellDividing_Macrophages-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

DEPDC1 HMMR BRCA2

1.27e-04169263bc859a103cad567caf50c3c3882d2d2017807c73
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DEPDC1 HMMR BRCA2

1.27e-04169263e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.27e-04169263b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.32e-0417126355c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DEPDC1 HMMR BRCA2

1.34e-041722636fcc16f1067672967ecbcdfdc727649ae9891dd9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.36e-04173263a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.38e-0417426384da9faff088d05233183b425385beb054c92d1b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.38e-041742637b318796728001c17b4043d2b033330c7be40c78
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.38e-04174263c26eac176e9b0cba385630fdc60e0314a4e4caac
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.38e-04174263dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DEPDC1 HMMR BRCA2

1.38e-0417426346cbb462173a684ceb9e680f9259dc3b133763f7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.41e-04175263876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DEPDC1 HMMR BRCA2

1.41e-041752636b4e841bde6cfa4956e1a0231672cea20f11210c
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN|PND07-28-samps / Age Group, Lineage, Cell class and subclass

RSPO3 ADAMTSL1 SRPX

1.43e-0417626308f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.46e-0417726373ba0f0b4b33f10e9f036d6d9befa48a1258e682
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_1|367C / Donor, Lineage, Cell class and subclass (all cells)

DEPDC1 HMMR BRCA2

1.46e-04177263ba701d3c90722d8bff70d0fa651899305cdad257
ToppCellDividing_Macrophages-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

DEPDC1 HMMR BRCA2

1.48e-041782631893fadac2ec3d5de0a641e57b7b2f962012a9ba
ToppCellDividing_Macrophages-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

DEPDC1 HMMR BRCA2

1.48e-041782636557688c6790a5bcc3b9aea5b8789cf9506b3c54
ToppCellfacs-Pancreas-Endocrine-24m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 ADAMTSL1 SRPX

1.51e-041792636f51a4580c06fc55cc764052c9b26f7c55660282
ToppCellfacs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 ADAMTSL1 SRPX

1.51e-04179263a6ce1fa338d4905bd6afef00763ac83e916a0b37
ToppCellfacs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 ADAMTSL1 SRPX

1.51e-04179263f14440f6ce9b4fcdd4bcb2488b949f9a0e17bc23
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DEPDC1 HMMR BRCA2

1.51e-04179263021d782134126c6f7dce6b6ea50cc54bdaa39987
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.53e-04180263401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DEPDC1 HMMR BRCA2

1.53e-04180263334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.53e-04180263f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 ADAMTSL1 SRPX

1.56e-04181263cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DEPDC1 HMMR CTDSPL

1.56e-04181263c5843b89f3d362e236ff76c3279518a2fdfc1f75
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DEPDC1 HMMR CTDSPL

1.56e-0418126314c2dd946e89ba578711c2d25935b6b3d319b701
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 ADAMTSL1 SRPX

1.56e-04181263269b39ac65790061d54eab47a8eeb024403f0348
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DEPDC1 HMMR CTDSPL

1.56e-04181263fcefb5902416c004631f4f8dd5c8f99fe3bd90bc
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HMMR BRCA2 CCNB3

1.56e-0418126373b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.56e-04181263e0c46e2d52c97893e5894a51d2699e8a8a11eefc
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DEPDC1 HMMR CTDSPL

1.56e-041812639dc0563453e24c9d1d975e2e0e1e272487e19908
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1|bone_marrow / Manually curated celltypes from each tissue

DEPDC1 HMMR BRCA2

1.56e-04181263ccd0ed30cea3fb41d34f28b3e8d80a94493bef3c
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 ADAMTSL1 SRPX

1.56e-04181263c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.58e-04182263336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DEPDC1 COIL TET1

1.58e-04182263d1c3cc2942faec7527a3c25869fd65c17899e5e4
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DEPDC1 HMMR CCDC136

1.58e-04182263fe46819c153a81911864473badc794f243705f98
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_Myeloid|bone_marrow / Manually curated celltypes from each tissue

DEPDC1 HMMR BRCA2

1.58e-041822636745d464c3ff289726aa8164e9a43f407f8e4380
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DEPDC1 COIL TET1

1.58e-0418226392f83f29e358000cd86a709eb8b6199761ffe8bd
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T|Liver / Manually curated celltypes from each tissue

DEPDC1 HMMR BRCA2

1.58e-0418226381557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DEPDC1 HMMR CCDC136

1.58e-041822633948422707d6d5e021bcd7158e2eb69143613f62
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DEPDC1 COIL TET1

1.58e-0418226302baca9a72c7b559c3e452693b3b134af804c868
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5|TCGA-Liver / Sample_Type by Project: Shred V9

DEPDC1 HMMR BRCA2

1.61e-04183263f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

DEPDC1 HMMR BRCA2

1.61e-04183263a716b446c2bf5aa294b8f580aa845098fae76354
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THRA ZKSCAN5 PML

1.63e-04184263a6dee97ee4ef9d89e11d17339e0dadaea1210ce5
ToppCellIIF-Lymphocyte-T_NK-T_NK_proliferative|IIF / Disease, Lineage and Cell Type

DEPDC1 HMMR BRCA2

1.63e-04184263ab8b45ce40e8c5f66e5c23332a591b4f9cba4ce1
ToppCellDividing_Macrophages-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

DEPDC1 HMMR BRCA2

1.63e-04184263f15ce786d25c6546804a6d1efcc2ad645f2ef54e
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

DEPDC1 HMMR BRCA2

1.66e-041852639766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.66e-0418526330e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellURO-Lymphocyte-T_NK-T_NK_proliferative|URO / Disease, Lineage and Cell Type

DEPDC1 HMMR BRCA2

1.66e-041852630ae9c646679c69a553eda670aef0e0495feb0286
ToppCellCOVID-19-Fibroblasts-Adventitial_FB|COVID-19 / group, cell type (main and fine annotations)

RSPO3 ADAMTSL1 SRPX

1.66e-04185263a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DEPDC1 ADAMTSL1 HMMR

1.69e-041862635d527050cd554cc46c6d8dcb7981900725d79fc6
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating-Lymphatic_EC_proliferating_L.2.5.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DEPDC1 ADAMTSL1 HMMR

1.69e-04186263ee1c3e2adfa2900542200a218746b576c7ed10dc
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.71e-04187263cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.71e-04187263057569c9437219ecc396aa6e673b1178a2273837
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 ADAMTSL1 SRPX

1.71e-041872634e553721fa5598cb211f44e3226280b7e6885484
ToppCelldroplet-Spleen-nan-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMMR THRA BRCA2

1.71e-04187263c81d11d9fdc22dc39222f62c2888025c2e8c3e65
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 ADAMTSL1 SRPX

1.71e-04187263d36e7fc6125e7a4310499365022d38f34b757a73
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 ADAMTSL1 SRPX

1.71e-04187263827eae63fabf6892a82ce7779b5f395958d3d628
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.71e-04187263e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.71e-041872639351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-T_NK_proliferative|Multiple_Sclerosis / Disease, Lineage and Cell Type

DEPDC1 HMMR BRCA2

1.74e-041882636c05797a5d0635d89ffcf4aca52178687129ccb4
ToppCellfacs-Kidney-nan-3m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 ADAMTSL1 SRPX

1.77e-04189263302b950a6ad578f8aeff7ea6fd15fe631225287d
ToppCellNS-critical-d_0-4-Lymphoid-NKT-proliferating|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DEPDC1 HMMR BRCA2

1.77e-04189263d6bd46abb072b13a6b72f1ca25d19f218cceb1ff
ToppCellfacs-Kidney-nan-3m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 ADAMTSL1 SRPX

1.77e-04189263a5306561026e4dfcc39beeb785e5108ac595d136
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DEPDC1 HMMR BRCA2

1.77e-041892631e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCellfacs-Kidney-nan-3m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 ADAMTSL1 SRPX

1.77e-04189263381058f55908f84375b54601d617389ef43ab855
ToppCellDividing_Macrophages-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

DEPDC1 HMMR BRCA2

1.77e-04189263d4e88a3e50499d683e3db38aee04490146fe30bb
ToppCellInt-URO-Lymphocyte-T_NK-T_NK_proliferative|Int-URO / Disease, Lineage and Cell Type

DEPDC1 HMMR BRCA2

1.79e-04190263005967c540418b85311308072a07c684f4296aef
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.79e-04190263185ae04c68f825cd346aa65072cc5da6a39dff4a
ToppCellNS-critical-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DEPDC1 BRCA2 CTDSPL

1.79e-041902637be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DEPDC1 HMMR BRCA2

1.79e-04190263b69940d16685249167d4c2cf6ad8237ccf6f7590
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1 HMMR BRCA2

1.79e-04190263e38dc41f2e79e3bd51326581c6ebe51927edb549
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Cycling_T|GI_small-bowel / Manually curated celltypes from each tissue

DEPDC1 HMMR BRCA2

1.82e-04191263e642fa7395c05fb53324c9d46bbc52f89fc9673f
DrugPropofol [2078-54-8]; Down 200; 22.4uM; PC3; HT_HG-U133A

BRCA2 KDM4C CTDSPL ZKSCAN5 PML

2.02e-061952556707_DN
DrugN-aminoimidazole

PPARD MOS

3.47e-063252CID005273583
DrugDB04006

PPARD CTDSPL PML

1.12e-0540253CID005289179
DrugHyoscyamine (L) [101-31-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A

THRA KDM4C CTDSPL PML

5.40e-051922542271_DN
DrugGly-His-Lys acetate salt; Down 200; 1uM; MCF7; HT_HG-U133A

BRCA2 KDM4C ZKSCAN5 PML

5.62e-051942546575_DN
DrugMedrysone [2668-66-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A

ZMYND11 KDM4C CTDSPL PML

5.62e-051942544727_DN
DrugPregnenolone [145-13-1]; Down 200; 12.6uM; MCF7; HT_HG-U133A

THRA BRCA2 ZKSCAN5 PML

5.85e-051962544802_DN
DrugLovastatin [75330-75-5]; Down 200; 9.8uM; HL60; HT_HG-U133A

THRA PPARD ZKSCAN5 PML

5.96e-051972542494_DN
DrugLomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A

PPARD CTDSPL ZKSCAN5 PML

5.96e-051972543620_DN
DrugGinkgolide A [15291-75-5]; Up 200; 9.8uM; HL60; HT_HG-U133A

THRA PPARD PML ASTE1

5.96e-051972541324_UP
DrugAjmalicine hydrochloride [4373-34-6]; Up 200; 10.2uM; PC3; HT_HG-U133A

THRA PPARD CTDSPL PML

5.96e-051972546360_UP
DrugSparteine (-) [90-39-1]; Down 200; 17uM; PC3; HT_HG-U133A

ZMYND11 BRCA2 CTDSPL PML

6.08e-051982544568_DN
DrugSv 1

ARPC3 MOS

1.56e-0417252CID000209652
DrugAC1OC6D1

THRA COIL CTDSPL

1.98e-04104253CID006368594
DrugAC1O5RQH

HMMR TET1

3.70e-0426252CID006439470
DrugNexus

THRA PPARD CCNB3

6.02e-04152253CID000098527
Drugtreprostinil sodium

HMMR PPARD

7.94e-0438252CID000054786
DrugRifabutin [72559-06-9]; Up 200; 4.8uM; MCF7; HT_HG-U133A

SRPX PPARD PML

9.06e-041752533873_UP
DrugCPG-oligonucleotide

UIMC1 BRCA2 ASTE1

1.05e-03184253ctd:C408982
DrugAmoxicillin [26787-78-0]; Down 200; 11uM; MCF7; HT_HG-U133A

ZMYND11 BRCA2 ASTE1

1.06e-031852532620_DN
DrugEtoposide [33419-42-0]; Down 200; 6.8uM; MCF7; HT_HG-U133A

HMMR BRCA2 CTDSPL

1.06e-031852533241_DN
DrugLoperamide hydrochloride [34552-83-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A

PPARD CTDSPL PML

1.08e-031862531533_UP
Drugrapamycin, Streptomyces hygroscepicus; Up 200; 0.1uM; PC3; HT_HG-U133A

THRA PPARD BRCA2

1.11e-031882535980_UP
Drug2-propylpentanoic acid; Down 200; 10000uM; HL60; HG-U133A

ZMYND11 THRA PML

1.13e-03189253410_DN
DrugEstradiol-17 beta [50-28-2]; Down 200; 14.6uM; PC3; HT_HG-U133A

ZMYND11 BRCA2 CTDSPL

1.15e-031902536718_DN
DrugChlorprothixene hydrochloride [6469-93-8]; Up 200; 11.4uM; MCF7; HT_HG-U133A

THRA KDM4C PML

1.17e-031912532627_UP
DrugMeticrane [1084-65-7]; Up 200; 14.6uM; PC3; HT_HG-U133A

KDM4C CTDSPL PML

1.18e-031922531792_UP
DrugNorethynodrel [68-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A

KDM4C ZKSCAN5 PML

1.18e-031922531696_UP
DrugDilazep dihydrochloride [20153-98-4]; Up 200; 6uM; PC3; HT_HG-U133A

CTDSPL ZKSCAN5 PML

1.18e-031922537364_UP
DrugCyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; HL60; HT_HG-U133A

THRA PPARD PML

1.18e-031922531332_UP
DrugOrlistat; Up 200; 10uM; PC3; HT_HG-U133A

PPARD BRCA2 PML

1.18e-031922536388_UP
DrugSulfadiazine [68-35-9]; Down 200; 16uM; HL60; HT_HG-U133A

KDM4C PML ASTE1

1.20e-031932531852_DN
DrugRapamycin; Down 200; 0.1uM; PC3; HT_HG-U133A

PPARD CTDSPL PML

1.20e-031932534431_DN
DrugDiethylstilbestrol [56-53-1]; Up 200; 15uM; MCF7; HT_HG-U133A

ZMYND11 SRPX CTDSPL

1.20e-031932533429_UP
DrugClotrimazole [23593-75-1]; Down 200; 11.6uM; PC3; HT_HG-U133A

PPARD KDM4C CTDSPL

1.20e-031932535726_DN
DrugIsoxsuprine hydrochloride [579-56-6]; Down 200; 11.8uM; PC3; HT_HG-U133A

THRA CTDSPL PML

1.20e-031932534205_DN
DrugEpirubicin

THRA PML

1.21e-0347252ctd:D015251
DrugPimethixene maleate [13187-06-9]; Down 200; 9.8uM; MCF7; HT_HG-U133A

BRCA2 CTDSPL ASTE1

1.22e-031942537468_DN
DrugCefmetazole sodium salt [56796-39-5]; Down 200; 8.2uM; HL60; HT_HG-U133A

THRA PPARD PML

1.22e-031942532524_DN
DrugLomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; PC3; HT_HG-U133A

THRA PPARD BRCA2

1.22e-031942534281_DN
DrugLY 294002; Up 200; 10uM; PC3; HT_HG-U133A

THRA PPARD PML

1.22e-031942531239_UP
DrugSulfamonomethoxine [1220-83-3]; Down 200; 14.2uM; HL60; HT_HG-U133A

ZMYND11 BRCA2 PML

1.22e-031942532742_DN
DrugDelcorine; Down 200; 8.4uM; PC3; HT_HG-U133A

PPARD CTDSPL PML

1.22e-031942534275_DN
DrugTetrandrine [518-34-3]; Down 200; 6.4uM; HL60; HT_HG-U133A

THRA PPARD PML

1.22e-031942532520_DN
DrugMetoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A

PPARD KDM4C PML

1.22e-031942533625_DN
DrugFelodipine [72509-76-3]; Down 200; 10.4uM; PC3; HT_HG-U133A

THRA BRCA2 CTDSPL

1.22e-031942536695_DN
DrugCyanocobalamin [68-19-9]; Down 200; 3uM; PC3; HT_HG-U133A

PPARD KDM4C PML

1.22e-031942534572_DN
DrugFosfosal [6064-83-1]; Down 200; 18.4uM; PC3; HT_HG-U133A

THRA CTDSPL PML

1.22e-031942534239_DN
Drug(-)-Quinpirole hydrochloride [85760-74-3]; Down 200; 15.6uM; MCF7; HT_HG-U133A

THRA CTDSPL ZKSCAN5

1.22e-031942533539_DN
DrugCholecalciferol [67-97-0]; Down 200; 10.4uM; PC3; HT_HG-U133A

PPARD BRCA2 PML

1.22e-031942536656_DN
DrugCarbamazepine [298-46-4]; Up 200; 17uM; PC3; HT_HG-U133A

ZMYND11 KDM4C PML

1.22e-031942531805_UP
DrugSertaconazole nitrate [99592-39-9]; Down 200; 8uM; HL60; HT_HG-U133A

THRA ZKSCAN5 PML

1.22e-031942536128_DN
DrugEtifenin [63245-28-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A

THRA KDM4C PML

1.22e-031942534117_UP
DrugSkimmianine [83-95-4]; Down 200; 15.4uM; HL60; HT_HG-U133A

PPARD KDM4C PML

1.22e-031942532504_DN
Drugprochlorperazine dimaleate salt; Down 200; 10uM; HL60; HT_HG-U133A

ZMYND11 KDM4C PML

1.24e-031952536174_DN
DrugAtovaquone [95233-18-4]; Down 200; 11uM; PC3; HT_HG-U133A

THRA ZKSCAN5 PML

1.24e-031952534201_DN
DrugNafronyl oxalate [3200-06-4]; Down 200; 8.4uM; HL60; HT_HG-U133A

BRCA2 ZKSCAN5 PML

1.24e-031952531267_DN
DrugDelcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A

THRA CTDSPL PML

1.24e-031952534737_DN
DrugTyloxapol [25301-02-4]; Down 200; 4uM; PC3; HT_HG-U133A

PPARD CTDSPL PML

1.24e-031952534611_DN
DrugTicarcillin sodium [4697-14-7]; Down 200; 9.4uM; HL60; HT_HG-U133A

KDM4C ZKSCAN5 PML

1.24e-031952536146_DN
DrugPHA-00767505E [723337-45-9]; Up 200; 10uM; PC3; HT_HG-U133A

PPARD KDM4C CTDSPL

1.24e-031952536545_UP
DrugHemicholinium bromide [312-45-8]; Down 200; 7uM; PC3; HT_HG-U133A

PPARD CTDSPL PML

1.24e-031952536739_DN
DrugCytisine (-) [485-35-8]; Down 200; 21uM; PC3; HT_HG-U133A

KDM4C CTDSPL PML

1.24e-031952535739_DN
DrugLidoflazine [3416-26-0]; Down 200; 8.2uM; MCF7; HT_HG-U133A

THRA CTDSPL PML

1.24e-031952533201_DN
DrugRamipril [87333-19-5]; Up 200; 9.6uM; PC3; HT_HG-U133A

PPARD CTDSPL PML

1.24e-031952537144_UP
Drug0173570-0000 [211245-44-2]; Down 200; 1uM; PC3; HT_HG-U133A

HMMR CTDSPL PML

1.26e-031962537391_DN
DrugBenzbromarone [3562-84-3]; Down 200; 9.4uM; PC3; HT_HG-U133A

ZMYND11 PPARD PML

1.26e-031962536669_DN
DrugAscorbic acid [50-81-7]; Up 200; 22.4uM; MCF7; HT_HG-U133A

KDM4C CTDSPL PML

1.26e-031962535407_UP
DrugBetazole hydrochloride; Down 200; 27uM; PC3; HT_HG-U133A

ZMYND11 KDM4C CTDSPL

1.26e-031962536344_DN
DrugAzapropazone [13539-59-8]; Down 200; 13.4uM; PC3; HT_HG-U133A

BRCA2 ZKSCAN5 PML

1.26e-031962537277_DN
DrugGossypol [303-45-7]; Down 200; 7.8uM; MCF7; HT_HG-U133A

THRA PPARD PML

1.26e-031962533637_DN
DrugCorynanthine hydrochloride [66634-44-4]; Down 200; 10.2uM; PC3; HT_HG-U133A

THRA KDM4C PML

1.26e-031962534227_DN
DrugRitodrine hydrochloride [23239-51-2]; Down 200; 12.4uM; PC3; HT_HG-U133A

BRCA2 CTDSPL PML

1.26e-031962534619_DN
DrugEvoxine [522-11-2]; Down 200; 11.6uM; HL60; HT_HG-U133A

PPARD ZKSCAN5 PML

1.26e-031962532186_DN
DrugStachydrine hydrochloride; Down 200; 22.2uM; PC3; HT_HG-U133A

KDM4C ZKSCAN5 PML

1.26e-031962534469_DN
DrugAllantoin [97-59-6]; Up 200; 25.2uM; PC3; HT_HG-U133A

PPARD CTDSPL PML

1.26e-031962535052_UP
DrugNomegestrol acetate [58652-20-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A

PPARD KDM4C PML

1.26e-031962535461_UP
Drug5194442; Up 200; 20uM; PC3; HT_HG-U133A

PPARD BRCA2 KDM4C

1.26e-031962536594_UP
Drug2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A

SRPX ZKSCAN5 PML

1.26e-031962531639_UP
DrugDimethadione [695-53-4]; Down 200; 31uM; HL60; HT_HG-U133A

ZMYND11 ZKSCAN5 PML

1.26e-031962533029_DN
DrugFluoxetine hydrochloride [59333-67-4]; Down 200; 11.6uM; PC3; HT_HG-U133A

THRA PPARD BRCA2

1.26e-031962536757_DN
DrugNaftifine hydrochloride [65473-14-5]; Down 200; 12.4uM; HL60; HT_HG-U133A

PPARD KDM4C ZKSCAN5

1.26e-031962532974_DN
DrugPF-00539745-00 [351321-33-0]; Up 200; 10uM; PC3; HT_HG-U133A

PPARD BRCA2 KDM4C

1.26e-031962535979_UP
DrugFoliosidine [2520-38-9]; Down 200; 13uM; MCF7; HT_HG-U133A

SRPX PPARD KDM4C

1.26e-031962536057_DN
DrugAcebutolol hydrochloride [34381-68-5]; Down 200; 10.8uM; PC3; HT_HG-U133A

THRA PPARD PML

1.26e-031962536631_DN
Diseasecup-to-disc ratio measurement

FAM76B RSPO3 HORMAD2 ADAMTSL1 TET1

2.68e-05430255EFO_0006939
DiseaseBREAST CANCER

HMMR BRCA2

1.43e-0421252114480
DiseaseMalignant tumor of breast

HMMR BRCA2

2.39e-0427252cv:C0006142
DiseaseBreast neoplasm

HMMR BRCA2

2.39e-0427252cv:C1458155
DiseaseFamilial cancer of breast

HMMR BRCA2

2.39e-0427252cv:C0346153
Diseasebreast cancer (is_implicated_in)

HMMR BRCA2 KDM4C

2.73e-04150253DOID:1612 (is_implicated_in)
Diseaseresponse to angiotensin receptor blocker

RSPO3 KDM4C

2.95e-0430252EFO_0010735
DiseaseAdult Medulloblastoma

BRCA2 KDM4C

6.09e-0443252C0278876
DiseaseChildhood Medulloblastoma

BRCA2 KDM4C

6.09e-0443252C0278510
DiseaseMelanotic medulloblastoma

BRCA2 KDM4C

6.09e-0443252C1275668
DiseaseMedullomyoblastoma

BRCA2 KDM4C

6.09e-0443252C0205833
DiseaseDesmoplastic Medulloblastoma

BRCA2 KDM4C

6.09e-0443252C0751291
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

BRCA2 KDM4C

6.67e-0445252DOID:3748 (is_implicated_in)
DiseaseLiver carcinoma

RSPO3 DEPDC1 SRPX HMMR

8.18e-04507254C2239176
DiseaseMedulloblastoma

BRCA2 KDM4C

8.23e-0450252C0025149
Diseasephysical activity measurement

PPARD ZKSCAN5 PML

1.14e-03245253EFO_0008002
Diseasemelanoma

PPARD BRCA2 KDM4C

1.18e-03248253C0025202
Diseaserenal cell carcinoma (is_implicated_in)

THRA KDM4C

1.56e-0369252DOID:4450 (is_implicated_in)
Diseasesmall cell lung carcinoma

ADAMTSL1 BRCA2

2.09e-0380252EFO_0000702
Diseasetreatment-resistant hypertension

RSPO3 KDM4C

3.84e-03109252EFO_1002006
Diseasebone density

RSPO3 ADAMTSL1 ZKSCAN5

4.19e-03388253EFO_0003923
Diseasespine bone mineral density

RSPO3 ZKSCAN5

4.55e-03119252EFO_0007701
Diseasecranial vault morphology measurement

RSPO3 ADAMTSL1

4.70e-03121252EFO_0009278

Protein segments in the cluster

PeptideGeneStartEntry
SNSKKKRQKKQNTSC

ASTE1

626

Q2TB18
KRQKKQNTSCSKNRG

ASTE1

631

Q2TB18
LKKKMCASQRKQSCQ

CCNB3

231

Q8WWL7
CSQQSSECSRKKRKV

HORMAD2

281

Q8N7B1
KQLKLCQLSQFKSRC

ADAMTSL1

1741

Q8N6G6
QTVSKKNKRKNKATC

COIL

156

P38432
KCKSKQLCRSQSLLL

DEPDC1

501

Q5TB30
RTFLKSSFQKKCQKR

KDM4C

1041

Q9H3R0
SKTNTICKKCAQNVK

FAM76B

51

Q5HYJ3
SKLRCQLAKKKQSET

HMMR

656

O75330
CFSKCRTKNLQKVRT

BRCA2

311

P51587
SECLKKLQKCNSKSQ

ARPC3

76

O15145
KASQCNVSLKKQRSR

CTDSPL

26

O15194
IKQVNKCTKNRLASR

MOS

86

P00540
CERSCKIQKKNRNKC

PPARD

111

Q03181
KRKCSQTQCPRKVIK

PML

476

P29590
NKRWSDKVICKQKRC

SRPX

106

P78539
NRKNSHQICKKRKCE

TET1

611

Q8NFU7
LAKSSKCNRNKQSKL

CCDC136

666

Q96JN2
LRKTCKSINECKVQK

ZNF718

111

Q3SXZ3
ASVRNICSKKQKKSA

STPG2

271

Q8N412
TRKCTVQRKKCQKGE

RSPO3

196

Q9BXY4
QCSKCKKTTRQRNLK

TRIM51G

51

A0A3B3IT33
QCPVCRSIKKKNTNK

ZMYND11

141

Q15326
KITRNQCQLCRFKKC

THRA

101

P10827
GLQKTKTKQSNRAKC

UIMC1

56

Q96RL1
KSQRCSDKRSKNTKL

ZKSCAN5

456

Q9Y2L8