Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	polyol transmembrane transporter activity	SLC2A13 AQP7P3 AQP7	3.44e-06	13	47	3	GO:0015166
GeneOntologyMolecularFunction	transporter activity	ATP13A4 TOMM7 ATP9B KCNK13 KCNK12 SLC2A13 SLC7A3 AQP7P3 NDUFA9 AQP7 ABCA9 CFTR PKD1	5.67e-06	1289	47	13	GO:0005215
GeneOntologyMolecularFunction	transmembrane transporter activity	ATP13A4 TOMM7 KCNK13 KCNK12 SLC2A13 SLC7A3 AQP7P3 NDUFA9 AQP7 ABCA9 CFTR PKD1	1.30e-05	1180	47	12	GO:0022857
GeneOntologyMolecularFunction	urea channel activity	AQP7P3 AQP7	5.40e-05	5	47	2	GO:0015265
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	ATP13A4 KCNK13 KCNK12 SLC2A13 AQP7P3 NDUFA9 AQP7 CFTR PKD1	5.82e-05	758	47	9	GO:0015318
GeneOntologyMolecularFunction	ATP hydrolysis activity	ATP13A4 ATP9B DNAH10 KIF1A ABCA9 KIF1B CFTR	7.16e-05	441	47	7	GO:0016887
GeneOntologyMolecularFunction	glycerol channel activity	AQP7P3 AQP7	1.13e-04	7	47	2	GO:0015254
GeneOntologyMolecularFunction	urea transmembrane transporter activity	AQP7P3 AQP7	1.93e-04	9	47	2	GO:0015204
GeneOntologyMolecularFunction	glycerol transmembrane transporter activity	AQP7P3 AQP7	1.93e-04	9	47	2	GO:0015168
GeneOntologyMolecularFunction	hydrolase activity, acting on glycosyl bonds	IL18RAP TREH HYAL2 MGAM2	3.64e-04	144	47	4	GO:0016798
GeneOntologyMolecularFunction	ATP-dependent activity	ATP13A4 ATP9B DNAH10 KIF1A ABCA9 KIF1B CFTR	5.42e-04	614	47	7	GO:0140657
GeneOntologyMolecularFunction	organic hydroxy compound transmembrane transporter activity	SLC2A13 AQP7P3 AQP7	5.99e-04	70	47	3	GO:1901618
GeneOntologyMolecularFunction	microtubule motor activity	DNAH10 KIF1A KIF1B	5.99e-04	70	47	3	GO:0003777
GeneOntologyMolecularFunction	potassium ion leak channel activity	KCNK13 KCNK12	6.37e-04	16	47	2	GO:0022841
GeneOntologyMolecularFunction	plus-end-directed microtubule motor activity	KIF1A KIF1B	7.21e-04	17	47	2	GO:0008574
GeneOntologyMolecularFunction	water channel activity	AQP7P3 AQP7	7.21e-04	17	47	2	GO:0015250
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ATP13A4 NDUFA9 ABCA9 CFTR	8.07e-04	178	47	4	GO:0015399
GeneOntologyMolecularFunction	narrow pore channel activity	KCNK13 KCNK12	9.04e-04	19	47	2	GO:0022842
GeneOntologyMolecularFunction	leak channel activity	KCNK13 KCNK12	9.04e-04	19	47	2	GO:0022840
GeneOntologyMolecularFunction	water transmembrane transporter activity	AQP7P3 AQP7	1.00e-03	20	47	2	GO:0005372
GeneOntologyMolecularFunction	channel activity	KCNK13 KCNK12 AQP7P3 AQP7 CFTR PKD1	1.38e-03	525	47	6	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	KCNK13 KCNK12 AQP7P3 AQP7 CFTR PKD1	1.39e-03	526	47	6	GO:0022803
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	TREH HYAL2 MGAM2	1.83e-03	103	47	3	GO:0004553
GeneOntologyMolecularFunction	outward rectifier potassium channel activity	KCNK13 KCNK12	1.83e-03	27	47	2	GO:0015271
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ATP13A4 ATP9B DNAH10 KIF1A ABCA9 KIF1B CFTR	2.10e-03	775	47	7	GO:0017111
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ATP13A4 ABCA9 CFTR	2.15e-03	109	47	3	GO:0042626
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	ATP13A4 KCNK13 KCNK12 SLC2A13 NDUFA9 CFTR PKD1	2.39e-03	793	47	7	GO:0015075
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNAH10 KIF1A KIF1B	2.70e-03	118	47	3	GO:0003774
GeneOntologyMolecularFunction	pyrophosphatase activity	ATP13A4 ATP9B DNAH10 KIF1A ABCA9 KIF1B CFTR	3.27e-03	839	47	7	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ATP13A4 ATP9B DNAH10 KIF1A ABCA9 KIF1B CFTR	3.29e-03	840	47	7	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ATP13A4 ATP9B DNAH10 KIF1A ABCA9 KIF1B CFTR	3.29e-03	840	47	7	GO:0016818
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	ATP13A4 KCNK13 KCNK12 SLC2A13 NDUFA9 PKD1	3.36e-03	627	47	6	GO:0022890
GeneOntologyMolecularFunction	carbohydrate transmembrane transporter activity	AQP7P3 AQP7	4.40e-03	42	47	2	GO:0015144
GeneOntologyMolecularFunction	amide transmembrane transporter activity	AQP7P3 AQP7	4.40e-03	42	47	2	GO:0042887
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	ATP13A4 KCNK13 KCNK12 SLC2A13 NDUFA9 PKD1	4.45e-03	664	47	6	GO:0008324
GeneOntologyMolecularFunction	active transmembrane transporter activity	ATP13A4 SLC2A13 NDUFA9 ABCA9 CFTR	5.12e-03	477	47	5	GO:0022804
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA9 CFTR	5.94e-03	49	47	2	GO:0140359
GeneOntologyBiologicalProcess	water transport	AQP7P3 AQP7 HYAL2 CFTR	7.44e-07	32	46	4	GO:0006833
GeneOntologyBiologicalProcess	multicellular organismal-level water homeostasis	AQP7P3 AQP7 HYAL2 CFTR	1.08e-06	35	46	4	GO:0050891
GeneOntologyBiologicalProcess	renal water absorption	AQP7P3 AQP7 HYAL2	1.23e-06	10	46	3	GO:0070295
GeneOntologyBiologicalProcess	fluid transport	AQP7P3 AQP7 HYAL2 CFTR	2.28e-06	42	46	4	GO:0042044
GeneOntologyBiologicalProcess	renal water transport	AQP7P3 AQP7 HYAL2	2.92e-06	13	46	3	GO:0003097
GeneOntologyBiologicalProcess	renal water homeostasis	AQP7P3 AQP7 HYAL2	2.60e-05	26	46	3	GO:0003091
GeneOntologyBiologicalProcess	multicellular organismal-level chemical homeostasis	AQP7P3 AQP7 HYAL2 CFTR	4.81e-05	90	46	4	GO:0140962
GeneOntologyBiologicalProcess	retrograde neuronal dense core vesicle transport	KIF1A KIF1B	7.26e-05	6	46	2	GO:1990049
GeneOntologyBiologicalProcess	anterograde neuronal dense core vesicle transport	KIF1A KIF1B	1.35e-04	8	46	2	GO:1990048
GeneOntologyBiologicalProcess	renal absorption	AQP7P3 AQP7 HYAL2	1.38e-04	45	46	3	GO:0070293
GeneOntologyBiologicalProcess	glycerol transmembrane transport	AQP7P3 AQP7	1.73e-04	9	46	2	GO:0015793
GeneOntologyBiologicalProcess	polyol transmembrane transport	AQP7P3 AQP7	3.17e-04	12	46	2	GO:0015791
GeneOntologyBiologicalProcess	dense core granule cytoskeletal transport	KIF1A KIF1B	3.17e-04	12	46	2	GO:0099519
GeneOntologyBiologicalProcess	urea transmembrane transport	AQP7P3 AQP7	3.17e-04	12	46	2	GO:0071918
GeneOntologyBiologicalProcess	urea transport	AQP7P3 AQP7	4.35e-04	14	46	2	GO:0015840
GeneOntologyBiologicalProcess	dense core granule transport	KIF1A KIF1B	4.35e-04	14	46	2	GO:1901950
MousePheno	decreased urine glycerol level	AQP7P3 AQP7	6.45e-06	2	36	2	MP:0030781
MousePheno	abnormal urine glycerol level	AQP7P3 AQP7	1.93e-05	3	36	2	MP:0030782
MousePheno	decreased PP cell number	AQP7P3 AQP7	9.61e-05	6	36	2	MP:0009186
MousePheno	dilated pancreatic duct	CFTR PKD1	1.79e-04	8	36	2	MP:0009144
MousePheno	abnormal PP cell morphology	AQP7P3 AQP7	1.79e-04	8	36	2	MP:0009184
MousePheno	pancreas atrophy	CFTR PKD1	1.79e-04	8	36	2	MP:0013295
Domain	2pore_dom_K_chnl_THIK	KCNK13 KCNK12	5.42e-06	2	44	2	IPR005410
Domain	Kinesin-like_KIF1-typ	KIF1A KIF1B	3.24e-05	4	44	2	IPR022140
Domain	KIF1B	KIF1A KIF1B	3.24e-05	4	44	2	PF12423
Domain	FerI	MYOF FER1L6	5.40e-05	5	44	2	SM01202
Domain	FerB	MYOF FER1L6	5.40e-05	5	44	2	SM01201
Domain	Ferlin_B-domain	MYOF FER1L6	5.40e-05	5	44	2	IPR012561
Domain	Ferlin_C	MYOF FER1L6	5.40e-05	5	44	2	PF16165
Domain	Ferlin_C	MYOF FER1L6	5.40e-05	5	44	2	IPR032362
Domain	FerIin_dom	MYOF FER1L6	5.40e-05	5	44	2	IPR012968
Domain	FerI	MYOF FER1L6	5.40e-05	5	44	2	PF08151
Domain	FerB	MYOF FER1L6	5.40e-05	5	44	2	PF08150
Domain	Kinesin_assoc	KIF1A KIF1B	8.09e-05	6	44	2	PF16183
Domain	Kinesin_assoc	KIF1A KIF1B	8.09e-05	6	44	2	IPR032405
Domain	DUF3694	KIF1A KIF1B	8.09e-05	6	44	2	PF12473
Domain	Kinesin-like	KIF1A KIF1B	8.09e-05	6	44	2	IPR022164
Domain	2pore_dom_K_chnl	KCNK13 KCNK12	5.59e-04	15	44	2	IPR003280
Domain	K_chnl_dom	KCNK13 KCNK12	1.11e-03	21	44	2	IPR013099
Domain	Ion_trans_2	KCNK13 KCNK12	1.11e-03	21	44	2	PF07885
Domain	FHA	KIF1A KIF1B	1.97e-03	28	44	2	SM00240
Domain	FHA_DOMAIN	KIF1A KIF1B	2.42e-03	31	44	2	PS50006
Domain	FHA	KIF1A KIF1B	2.42e-03	31	44	2	PF00498
Domain	-	ATP13A4 ATP9B	2.57e-03	32	44	2	3.40.1110.10
Domain	-	ATP13A4 ATP9B	2.57e-03	32	44	2	2.70.150.10
Domain	ATPase_P-typ_cyto_domN	ATP13A4 ATP9B	3.07e-03	35	44	2	IPR023299
Domain	FHA_dom	KIF1A KIF1B	3.25e-03	36	44	2	IPR000253
Domain	P_typ_ATPase	ATP13A4 ATP9B	3.25e-03	36	44	2	IPR001757
Domain	ATPase_P-typ_P_site	ATP13A4 ATP9B	3.25e-03	36	44	2	IPR018303
Domain	ATPASE_E1_E2	ATP13A4 ATP9B	3.25e-03	36	44	2	PS00154
Domain	-	KIF1A KIF1B	3.25e-03	36	44	2	2.60.200.20
Domain	ATPase_P-typ_transduc_dom_A	ATP13A4 ATP9B	3.43e-03	37	44	2	IPR008250
Domain	E1-E2_ATPase	ATP13A4 ATP9B	3.43e-03	37	44	2	PF00122
Domain	Kinesin_motor_CS	KIF1A KIF1B	4.20e-03	41	44	2	IPR019821
Domain	Kinesin-like_fam	KIF1A KIF1B	4.61e-03	43	44	2	IPR027640
Domain	AAA+_ATPase	DNAH10 ABCA9 CFTR	4.72e-03	144	44	3	IPR003593
Domain	AAA	DNAH10 ABCA9 CFTR	4.72e-03	144	44	3	SM00382
Domain	KINESIN_MOTOR_1	KIF1A KIF1B	4.82e-03	44	44	2	PS00411
Domain	-	KIF1A KIF1B	4.82e-03	44	44	2	3.40.850.10
Domain	Kinesin_motor_dom	KIF1A KIF1B	4.82e-03	44	44	2	IPR001752
Domain	Kinesin	KIF1A KIF1B	4.82e-03	44	44	2	PF00225
Domain	KINESIN_MOTOR_2	KIF1A KIF1B	4.82e-03	44	44	2	PS50067
Domain	KISc	KIF1A KIF1B	4.82e-03	44	44	2	SM00129
Domain	ABC_tran	ABCA9 CFTR	5.71e-03	48	44	2	PF00005
Domain	ABC_TRANSPORTER_2	ABCA9 CFTR	5.71e-03	48	44	2	PS50893
Domain	ABC_TRANSPORTER_1	ABCA9 CFTR	5.95e-03	49	44	2	PS00211
Domain	ABC_transporter-like	ABCA9 CFTR	6.18e-03	50	44	2	IPR003439
Domain	SMAD_FHA_domain	KIF1A KIF1B	6.67e-03	52	44	2	IPR008984
Domain	Glycoside_hydrolase_SF	HYAL2 MGAM2	6.93e-03	53	44	2	IPR017853
Pubmed	PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression.	IL20RB AQP7P3 AQP7 CFTR	2.86e-07	41	47	4	21282332
Pubmed	THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels.	KCNK13 KCNK12	1.79e-06	2	47	2	11060316
Pubmed	Cryoprotectants up-regulate expression of mouse oocyte AQP7, which facilitates water diffusion during cryopreservation.	AQP7P3 AQP7	1.79e-06	2	47	2	23290745
Pubmed	Morphologic and functional analysis of sperm and testes in Aquaporin 7 knockout mice.	AQP7P3 AQP7	1.79e-06	2	47	2	17123523
Pubmed	Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9.	AQP7P3 AQP7	1.79e-06	2	47	2	11972053
Pubmed	Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue.	AQP7P3 AQP7	1.79e-06	2	47	2	15591341
Pubmed	Aquaporin-7 Facilitates Proliferation and Adipogenic Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells by Regulating Hydrogen Peroxide Transport.	AQP7P3 AQP7	1.79e-06	2	47	2	37432580
Pubmed	Ouabain Regulates CFTR-Mediated Anion Secretion and Na,K-ATPase Transport in ADPKD Cells.	CFTR PKD1	1.79e-06	2	47	2	26289599
Pubmed	Aquaporin 7 is a beta-cell protein and regulator of intraislet glycerol content and glycerol kinase activity, beta-cell mass, and insulin production and secretion.	AQP7P3 AQP7	1.79e-06	2	47	2	17576812
Pubmed	Over-expression of AQP7 contributes to improve insulin resistance in adipocytes.	AQP7P3 AQP7	1.79e-06	2	47	2	22877989
Pubmed	Progressive adipocyte hypertrophy in aquaporin-7-deficient mice: adipocyte glycerol permeability as a novel regulator of fat accumulation.	AQP7P3 AQP7	1.79e-06	2	47	2	15746100
Pubmed	Aquaporin-7 Regulates the Response to Cellular Stress in Breast Cancer.	AQP7P3 AQP7	1.79e-06	2	47	2	32631905
Pubmed	Aquaporin7 plays a crucial role in tolerance to hyperosmotic stress and in the survival of oocytes during cryopreservation.	AQP7P3 AQP7	1.79e-06	2	47	2	26634435
Pubmed	Early embryonic renal tubules of wild-type and polycystic kidney disease kidneys respond to cAMP stimulation with cystic fibrosis transmembrane conductance regulator/Na(+),K(+),2Cl(-) Co-transporter-dependent cystic dilation.	CFTR PKD1	1.79e-06	2	47	2	17108316
Pubmed	Tandem pore domain halothane-inhibited K+ channel subunits THIK1 and THIK2 assemble and form active channels.	KCNK13 KCNK12	1.79e-06	2	47	2	25148687
Pubmed	Regulation of the two-pore domain potassium channel, THIK-1 and THIK-2, by G protein coupled receptors.	KCNK13 KCNK12	1.79e-06	2	47	2	37099539
Pubmed	The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors.	KIF1A KIF1B	1.79e-06	2	47	2	7539720
Pubmed	Aquaporin 7 expression in postimplantation mouse uteri: a potential role for glycerol transport in uterine decidualization.	AQP7P3 AQP7	1.79e-06	2	47	2	21130427
Pubmed	Cellular localization of THIK-1 (K(2P)13.1) and THIK-2 (K(2P)12.1) K channels in the mammalian kidney.	KCNK13 KCNK12	1.79e-06	2	47	2	18209473
Pubmed	Genomic structure and insulin-mediated repression of the aquaporin adipose (AQPap), adipose-specific glycerol channel.	AQP7P3 AQP7	1.79e-06	2	47	2	11457862
Pubmed	The heart requires glycerol as an energy substrate through aquaporin 7, a glycerol facilitator.	AQP7P3 AQP7	1.79e-06	2	47	2	19297367
Pubmed	The chloride channel CFTR is not required for cyst growth in an ADPKD mouse model.	CFTR PKD1	1.79e-06	2	47	2	34473378
Pubmed	AQP7 is localized in capillaries of adipose tissue, cardiac and striated muscle: implications in glycerol metabolism.	AQP7P3 AQP7	1.79e-06	2	47	2	17077387
Pubmed	Cardioprotective effect of St. Thomas' Hospital No. 2 solution against age-related changes in aquaporin-7-deficient mice.	AQP7P3 AQP7	1.79e-06	2	47	2	37691043
Pubmed	Dynamic subcellular localization of aquaporin-7 in white adipocytes.	AQP7P3 AQP7	1.79e-06	2	47	2	25643985
Pubmed	Aquaporin 7 is upregulated through the PI3K-Akt pathway and modulates decidualisation of endometrial stromal cells.	AQP7P3 AQP7	1.79e-06	2	47	2	37879294
Pubmed	Molecular characterization of human Aquaporin-7 gene and its chromosomal mapping.	AQP7P3 AQP7	1.79e-06	2	47	2	9714739
Pubmed	Aquaporin7 expression during perinatal development of mouse brain.	AQP7P3 AQP7	1.79e-06	2	47	2	17052846
Pubmed	Prolonged Starvation Causes Up-Regulation of AQP1 in Adipose Tissue Capillaries of AQP7 Knock-Out Mice.	AQP7P3 AQP7	1.79e-06	2	47	2	27455244
Pubmed	Involvement of aquaporin-7 in the cutaneous primary immune response through modulation of antigen uptake and migration in dendritic cells.	AQP7P3 AQP7	1.79e-06	2	47	2	21968069
Pubmed	A new role for aquaporin 7 in insulin secretion.	AQP7P3 AQP7	1.79e-06	2	47	2	22415076
Pubmed	Coordinated regulation of fat-specific and liver-specific glycerol channels, aquaporin adipose and aquaporin 9.	AQP7P3 AQP7	5.36e-06	3	47	2	12351427
Pubmed	Anti-obesity effect of carboxymethyl chitin by AMPK and aquaporin-7 pathways in 3T3-L1 adipocytes.	AQP7P3 AQP7	5.36e-06	3	47	2	20573496
Pubmed	BORC Functions Upstream of Kinesins 1 and 3 to Coordinate Regional Movement of Lysosomes along Different Microtubule Tracks.	KIF1A KIF1B	5.36e-06	3	47	2	27851960
Pubmed	Defective water and glycerol transport in the proximal tubules of AQP7 knockout mice.	AQP7P3 AQP7	5.36e-06	3	47	2	15998844
Pubmed	Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase.	AQP7P3 AQP7	5.36e-06	3	47	2	16009937
Pubmed	In vivo optical trapping indicates kinesin's stall force is reduced by dynein during intracellular transport.	KIF1A KIF1B	5.36e-06	3	47	2	23404705
Pubmed	Expression of aquaporin-7 and aquaporin-9 in tanycyte cells and choroid plexus during mouse estrus cycle.	AQP7P3 AQP7	5.36e-06	3	47	2	27746040
Pubmed	Adipocyte lipolysis drives acute stress-induced insulin resistance.	AQP7P3 AQP7	5.36e-06	3	47	2	33097799
Pubmed	Association of Aquaporin 7 and 9 with Obesity and Fatty Liver in db/db Mice.	AQP7P3 AQP7	5.36e-06	3	47	2	38064372
Pubmed	Channel-dependent permeation of water and glycerol in mouse morulae.	AQP7P3 AQP7	5.36e-06	3	47	2	16339044
Pubmed	Aquaporin isoforms involved in physiological volume regulation of murine spermatozoa.	AQP7P3 AQP7	5.36e-06	3	47	2	18829704
Pubmed	LPL/AQP7/GPD2 promotes glycerol metabolism under hypoxia and prevents cardiac dysfunction during ischemia.	AQP7P3 AQP7	1.07e-05	4	47	2	34807469
Pubmed	The mouse follicle microenvironment regulates antrum formation and steroid production: alterations in gene expression profiles.	AQP7P3 AQP7	1.07e-05	4	47	2	19005169
Pubmed	Molecular mechanism of the increased tissue uptake of trivalent inorganic arsenic in mice with type 1 diabetes mellitus.	AQP7P3 AQP7	1.07e-05	4	47	2	29890131
Pubmed	Fasting-induced increases in aquaporin 7 and adipose triglyceride lipase mRNA expression in adipose tissue are attenuated by peroxisome proliferator-activated receptor alpha deficiency.	AQP7P3 AQP7	1.07e-05	4	47	2	17245390
Pubmed	Human aquaporin adipose (AQPap) gene. Genomic structure, promoter analysis and functional mutation.	AQP7P3 AQP7	1.07e-05	4	47	2	11952783
Pubmed	The Molecular Motor KIF1A Transports the TrkA Neurotrophin Receptor and Is Essential for Sensory Neuron Survival and Function.	KIF1A KIF1B	1.07e-05	4	47	2	27263974
Pubmed	KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD.	KIF1A KIF1B	1.78e-05	5	47	2	18849981
Pubmed	More than just water channels: unexpected cellular roles of aquaporins.	AQP7P3 AQP7	1.78e-05	5	47	2	16079275
Pubmed	Restricted expression of mouse GCMa/Gcm1 in kidney and thymus.	AQP7P3 AQP7	2.67e-05	6	47	2	12351183
Pubmed	Role of aquaporin water channels in kidney and lung.	AQP7P3 AQP7	3.74e-05	7	47	2	9822113
Pubmed	Lessons on renal physiology from transgenic mice lacking aquaporin water channels.	AQP7P3 AQP7	3.74e-05	7	47	2	10232700
Pubmed	HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus.	KIF1A KIF1B	4.98e-05	8	47	2	25818806
Pubmed	Aquaporin molecular biology and clinical abnormalities of the water transport channels.	AQP7P3 AQP7	6.40e-05	9	47	2	9757370
Pubmed	Expression patterns of aquaporins in the inner ear: evidence for concerted actions of multiple types of aquaporins to facilitate water transport in the cochlea.	AQP7P3 AQP7	7.99e-05	10	47	2	12031518
Pubmed	mRNAs encoding aquaporins are present during murine preimplantation development.	AQP7P3 AQP7	7.99e-05	10	47	2	11066060
Pubmed	Expression of mRNAs of the aquaporin family in mouse oocytes and embryos.	AQP7P3 AQP7	7.99e-05	10	47	2	10788316
Pubmed	Potassium leak channels and the KCNK family of two-P-domain subunits.	KCNK13 KCNK12	1.17e-04	12	47	2	11256078
Pubmed	Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1.	KIF1A KIF1B	1.17e-04	12	47	2	16301330
Pubmed	Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism.	DNAH10 BAZ1A DHFR	1.83e-04	81	47	3	32060556
Pubmed	Aquaporins 8 and 9 as Possible Markers for Adult Murine Lacrimal Gland Cells.	AQP7P3 AQP7	1.86e-04	15	47	2	34540996
Pubmed	The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse.	CFTR PKD1	2.40e-04	17	47	2	16472605
Pubmed	Polyhydramnios in Lrp4 knockout mice with bilateral kidney agenesis: Defects in the pathways of amniotic fluid clearance.	AQP7P3 AQP7	2.40e-04	17	47	2	26847765
Pubmed	Expression patterns of the aquaporin gene family during renal development: influence of genetic variability.	AQP7P3 AQP7	3.01e-04	19	47	2	19367412
Pubmed	Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.	SLC2A13 IL18RAP	4.06e-04	22	47	2	25642632
Pubmed	Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis.	FOXD1 PKD1	4.06e-04	22	47	2	27582005
Pubmed	Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.	KIF1A KIF1B	5.26e-04	25	47	2	9275178
Pubmed	Murine chromosomal location of eight members of the hepatocyte nuclear factor 3/fork head winged helix family of transcription factors.	DHFR FOXD1	7.09e-04	29	47	2	7789972
Pubmed	Lipid-orchestrated paracrine circuit coordinates mast cell maturation and anaphylaxis through functional interaction with fibroblasts.	PTGIR LPAR6	9.19e-04	33	47	2	39002541
Pubmed	All kinesin superfamily protein, KIF, genes in mouse and human.	KIF1A KIF1B	1.16e-03	37	47	2	11416179
Pubmed	Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay.	FOXD1 PKD1	1.16e-03	37	47	2	16319116
GeneFamily	Ferlin family	MYOF FER1L6	4.25e-05	6	31	2	828
GeneFamily	Potassium two pore domain channel subfamily K	KCNK13 KCNK12	2.95e-04	15	31	2	277
GeneFamily	CD molecules\|I-set domain containing\|Immunoglobulin like domain containing\|Interleukin receptors\|TIR domain containing	IL20RB IL18RAP	2.35e-03	42	31	2	602
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF1A KIF1B	2.81e-03	46	31	2	622
CoexpressionAtlas	kidney_adult_RenalCapsule_k-means-cluster#2_top-relative-expression-ranked_500	MYOF ABCA9 FOXD1	2.12e-05	25	46	3	gudmap_kidney_adult_RenalCapsule_k2_500
Drug	Propoxycaine hydrochloride [550-83-4]; Up 200; 12uM; PC3; HT_HG-U133A	RNFT1 ATP9B RNF31 KIF1A JMJD6 LPAR6	2.03e-06	196	44	6	7155_UP
Drug	agent i	RNASEH2A DHFR	1.09e-05	3	44	2	CID000092357
Disease	synucleinopathy (biomarker_via_orthology)	KIF1A KIF1B	1.36e-05	4	45	2	DOID:0050890 (biomarker_via_orthology)
Disease	limb-girdle muscular dystrophy (implicated_via_orthology)	MYOF FER1L6	4.75e-05	7	45	2	DOID:11724 (implicated_via_orthology)
Disease	nervous system disease (implicated_via_orthology)	KIF1A KIF1B	1.49e-04	12	45	2	DOID:863 (implicated_via_orthology)
Disease	obsessive-compulsive symptom measurement	TAAR2 ATP13A4	1.03e-03	31	45	2	EFO_0007802

Protein segments in the cluster

Peptide	Gene	Start	Entry
GLWTLRAFGRQPYFE	CFTR	1061	P13569
FSFGILPLVFYWRPA	ATP13A4	41	Q4VNC1
GFPALYTRLPAFLEW	ABCA9	346	Q8IUA7
YRRYWIFPSIPGLFI	BAZ1A	811	Q9NRL2
SGRFPYYREKFPAWQ	FOXD1	156	Q16676
RFGFERVFNPVIKWY	IL18RAP	276	O95256
AVRPRHLWGFYLFPD	HYAL2	196	Q12891
FQYAGEKRRPPYRWF	JMJD6	161	Q6NYC1
RFDYSPEFLLWALRP	NMT2	191	O60551
FFPPYWSLGFQLSRR	MGAM2	326	Q2M2H8
DPFYDRSPWFILVGR	KIF1B	961	O60333
RVPWRKFPVYVLGQF	AQP7P3	106	A6NL99
FVGPWYRNLFRFLLL	ATP9B	401	O43861
RPRWDFPGAFYFVGT	KCNK12	111	Q9HB15
AQRGRIRYGPWYFEP	FAM47B	541	Q8NA70
PTIFYRDCWIRRFPG	MANSC4	26	A6NHS7
LRGLWLYGNRFEEFP	LRRC10B	161	A6NIK2
VRPRWDFTGAFYFVG	KCNK13	91	Q9HB14
PFRIFYFTTRNWPFG	LPAR6	71	P43657
RVPWRKFPVYVLGQF	AQP7	106	O14520
WYGSARLFRFRVPPD	PGAP6	61	Q9HCN3
GFLFWSPLQSARRPY	SMPD3	81	Q9NY59
FPLPLFAYRWVARVF	NDUFA9	291	Q16795
FEFWLPRERYSPFQA	ADAMTSL5	306	Q6ZMM2
PQFEFLVAYWRREPG	IL20RB	161	Q6UXL0
PVAFRYFWELFGIRP	PIPSL	91	A2A3N6
GDLPWPPLRNEFRYF	DHFR	21	P00374
PPVAGAIYWERSLFF	DNAH10	566	Q8IVF4
LPEAFLYIGWAPARY	SLC7A3	321	Q8WY07
DRFWVRGEGPIFFYT	DPP7	61	Q9UHL4
GGDPFYDRFPWFRLV	KIF1A	836	Q12756
YDRFPWFRLVGRAFV	KIF1A	841	Q12756
PGAPYALWREFLFSV	PKD1	676	P98161
IQFFGFLFLPESPRW	SLC2A13	251	Q96QE2
FPLERPWARFYVRLY	FER1L6	236	Q2WGJ9
PVFGFPQFVRFSWRT	RNASEH2A	226	O75792
RPRYWRGVKFNNPVF	RNF31	91	Q96EP0
YRTFVPIPVWFRYLI	RNFT1	296	Q5M7Z0
PIPVWFRYLISYGEF	RNFT1	301	Q5M7Z0
GPAFYVAFRSRPWNE	TEX13D	31	A0A0J9YY54
RLYIRSNPDLYGPFW	YIPF1	111	Q9Y548
FLWTIRRDPPAYLFG	TRABD2B	41	A6NFA1
LAFRFYAFNPILDPW	PTGIR	276	P43119
PFIVPGGRFVEFYYW	TREH	161	O43280
LAFPWTFPFGIDRRI	ZBTB44	226	Q8NCP5
NPLIYGFFYPWFRRA	TAAR2	311	Q9P1P5
FAIRWGFIPLVIYLG	TOMM7	21	Q9P0U1
WFFEEFVPGVKRYLR	TIGD5	331	Q53EQ6
WRFVFPFDYLPAEQL	MYOF	1846	Q9NZM1