Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	high-affinity IgG receptor activity	FCGR1A FCGR1BP	4.75e-06	2	44	2	GO:0019771
GeneOntologyMolecularFunction	leukotriene receptor binding	FCGR1A FCGR1BP	4.75e-06	2	44	2	GO:0031774
GeneOntologyMolecularFunction	IgG receptor activity	FCGR1A FCGR1BP	9.90e-05	7	44	2	GO:0019770
GeneOntologyMolecularFunction	IgG binding	FCGR1A FCGR1BP	2.58e-04	11	44	2	GO:0019864
GeneOntologyMolecularFunction	phosphatase binding	AKAP11 SMG7 MAST2 GAB2 GAB4	2.77e-04	264	44	5	GO:0019902
GeneOntologyMolecularFunction	immunoglobulin receptor activity	FCGR1A FCGR1BP	4.25e-04	14	44	2	GO:0019763
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase adaptor activity	GAB2 GAB4	7.10e-04	18	44	2	GO:0005068
GeneOntologyMolecularFunction	protein phosphatase binding	AKAP11 SMG7 GAB2 GAB4	1.16e-03	210	44	4	GO:0019903
GeneOntologyBiologicalProcess	regulation of myeloid leukocyte mediated immunity	FCGR1A FCGR1BP GAB2 GAB4	2.91e-05	81	45	4	GO:0002886
GeneOntologyBiologicalProcess	regulation of synaptic plasticity	CPEB3 SORCS2 TSHZ3 ATP1A3 TNR CNTN2	3.99e-05	293	45	6	GO:0048167
GeneOntologyBiologicalProcess	type III hypersensitivity	FCGR1A FCGR1BP	4.63e-05	5	45	2	GO:0001802
GeneOntologyBiologicalProcess	regulation of type III hypersensitivity	FCGR1A FCGR1BP	4.63e-05	5	45	2	GO:0001803
GeneOntologyBiologicalProcess	positive regulation of type III hypersensitivity	FCGR1A FCGR1BP	4.63e-05	5	45	2	GO:0001805
GeneOntologyBiologicalProcess	sensory perception of touch	TSHZ3 KCNK4	9.71e-05	7	45	2	GO:0050975
GeneOntologyBiologicalProcess	positive regulation of type II hypersensitivity	FCGR1A FCGR1BP	2.07e-04	10	45	2	GO:0002894
GeneOntologyBiologicalProcess	positive regulation of type IIa hypersensitivity	FCGR1A FCGR1BP	2.07e-04	10	45	2	GO:0001798
GeneOntologyBiologicalProcess	regulation of type II hypersensitivity	FCGR1A FCGR1BP	2.53e-04	11	45	2	GO:0002892
GeneOntologyBiologicalProcess	regulation of type IIa hypersensitivity	FCGR1A FCGR1BP	2.53e-04	11	45	2	GO:0001796
GeneOntologyBiologicalProcess	myeloid leukocyte mediated immunity	FCGR1A FCGR1BP GAB2 GAB4	3.02e-04	148	45	4	GO:0002444
GeneOntologyBiologicalProcess	antibody-dependent cellular cytotoxicity	FCGR1A FCGR1BP	3.58e-04	13	45	2	GO:0001788
GeneOntologyBiologicalProcess	presynaptic membrane organization	PTPRD CNTN2	3.58e-04	13	45	2	GO:0097090
GeneOntologyBiologicalProcess	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	CPEB3 TNRC6B	4.17e-04	14	45	2	GO:0060213
GeneOntologyBiologicalProcess	positive regulation of hypersensitivity	FCGR1A FCGR1BP	4.80e-04	15	45	2	GO:0002885
GeneOntologyBiologicalProcess	type IIa hypersensitivity	FCGR1A FCGR1BP	4.80e-04	15	45	2	GO:0001794
GeneOntologyBiologicalProcess	type II hypersensitivity	FCGR1A FCGR1BP	4.80e-04	15	45	2	GO:0002445
GeneOntologyBiologicalProcess	modulation of chemical synaptic transmission	CPEB3 SORCS2 TSHZ3 PTPRD ATP1A3 TNR CNTN2	5.38e-04	663	45	7	GO:0050804
GeneOntologyBiologicalProcess	regulation of trans-synaptic signaling	CPEB3 SORCS2 TSHZ3 PTPRD ATP1A3 TNR CNTN2	5.43e-04	664	45	7	GO:0099177
GeneOntologyBiologicalProcess	regulation of leukocyte mediated immunity	FCGR1A FCGR1BP MUC4 GAB2 GAB4	5.46e-04	309	45	5	GO:0002703
GeneOntologyBiologicalProcess	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	CPEB3 TNRC6B	5.48e-04	16	45	2	GO:1900153
GeneOntologyBiologicalProcess	regulation of nuclear-transcribed mRNA poly(A) tail shortening	CPEB3 TNRC6B	5.48e-04	16	45	2	GO:0060211
GeneOntologyBiologicalProcess	neuromuscular process controlling balance	ATP1A3 BLOC1S4 TNR	5.64e-04	74	45	3	GO:0050885
GeneOntologyBiologicalProcess	positive regulation of acute inflammatory response to antigenic stimulus	FCGR1A FCGR1BP	6.20e-04	17	45	2	GO:0002866
GeneOntologyBiologicalProcess	positive regulation of phagocytosis, engulfment	FCGR1A FCGR1BP	6.96e-04	18	45	2	GO:0060100
GeneOntologyBiologicalProcess	positive regulation of membrane invagination	FCGR1A FCGR1BP	6.96e-04	18	45	2	GO:1905155
GeneOntologyBiologicalProcess	antigen processing and presentation of exogenous peptide antigen via MHC class I	FCGR1A FCGR1BP	6.96e-04	18	45	2	GO:0042590
GeneOntologyBiologicalProcess	regulation of hypersensitivity	FCGR1A FCGR1BP	7.77e-04	19	45	2	GO:0002883
GeneOntologyBiologicalProcess	anterograde trans-synaptic signaling	CPEB3 SORCS2 ANKS1B TSHZ3 PTPRD ATP1A3 TNR CNTN2	8.15e-04	931	45	8	GO:0098916
GeneOntologyBiologicalProcess	chemical synaptic transmission	CPEB3 SORCS2 ANKS1B TSHZ3 PTPRD ATP1A3 TNR CNTN2	8.15e-04	931	45	8	GO:0007268
GeneOntologyBiologicalProcess	trans-synaptic signaling	CPEB3 SORCS2 ANKS1B TSHZ3 PTPRD ATP1A3 TNR CNTN2	8.61e-04	939	45	8	GO:0099537
GeneOntologyBiologicalProcess	cell recognition	FCGR1A FCGR1BP UBAP2L CNTN2	9.02e-04	198	45	4	GO:0008037
GeneOntologyBiologicalProcess	synaptic signaling	CPEB3 SORCS2 ANKS1B TSHZ3 PTPRD ATP1A3 TNR CNTN2	1.11e-03	976	45	8	GO:0099536
GeneOntologyBiologicalProcess	positive regulation of inflammatory response to antigenic stimulus	FCGR1A FCGR1BP	1.14e-03	23	45	2	GO:0002863
GeneOntologyBiologicalProcess	regulation of phagocytosis, engulfment	FCGR1A FCGR1BP	1.25e-03	24	45	2	GO:0060099
GeneOntologyBiologicalProcess	learning or memory	CPEB3 ATP1A3 TNR KCNK4 CNTN2	1.27e-03	373	45	5	GO:0007611
GeneOntologyBiologicalProcess	positive regulation of phagocytosis	FCGR1A FCGR1BP IL2RB	1.31e-03	99	45	3	GO:0050766
GeneOntologyBiologicalProcess	regulation of membrane invagination	FCGR1A FCGR1BP	1.35e-03	25	45	2	GO:1905153
GeneOntologyBiologicalProcess	hypersensitivity	FCGR1A FCGR1BP	1.35e-03	25	45	2	GO:0002524
GeneOntologyBiologicalProcess	neuromuscular process	TSHZ3 ATP1A3 BLOC1S4 TNR	1.45e-03	225	45	4	GO:0050905
GeneOntologyBiologicalProcess	regulation of excitatory synapse assembly	PTPN13 PTPRD	1.46e-03	26	45	2	GO:1904889
GeneOntologyBiologicalProcess	lens development in camera-type eye	CRYBA2 NHS SHROOM2	1.47e-03	103	45	3	GO:0002088
GeneOntologyBiologicalProcess	leukocyte mediated immunity	FCGR1A FCGR1BP IL2RB MUC4 GAB2 GAB4	1.49e-03	576	45	6	GO:0002443
GeneOntologyBiologicalProcess	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	CPEB3 TNRC6B	1.58e-03	27	45	2	GO:1900151
GeneOntologyBiologicalProcess	positive regulation of mast cell degranulation	GAB2 GAB4	1.58e-03	27	45	2	GO:0043306
GeneOntologyBiologicalProcess	regulation of acute inflammatory response to antigenic stimulus	FCGR1A FCGR1BP	1.58e-03	27	45	2	GO:0002864
GeneOntologyBiologicalProcess	positive regulation of myeloid leukocyte mediated immunity	FCGR1A FCGR1BP	1.95e-03	30	45	2	GO:0002888
GeneOntologyBiologicalProcess	cognition	CPEB3 ATP1A3 TNR KCNK4 CNTN2	2.20e-03	423	45	5	GO:0050890
GeneOntologyBiologicalProcess	nuclear-transcribed mRNA poly(A) tail shortening	CPEB3 TNRC6B	2.35e-03	33	45	2	GO:0000289
GeneOntologyCellularComponent	keratohyalin granule	HRNR FLG2	4.51e-05	5	45	2	GO:0036457
GeneOntologyCellularComponent	hippocampal mossy fiber to CA3 synapse	ANKS1B PTPRD TNR	4.06e-04	67	45	3	GO:0098686
MousePheno	abnormal vesicle-mediated transport	FCGR1A FCGR1BP BLOC1S4 GAB2 GAB4	5.30e-05	156	37	5	MP:0008546
MousePheno	decreased susceptibility to autoimmune hemolytic anemia	FCGR1A FCGR1BP	6.78e-05	5	37	2	MP:0004828
MousePheno	abnormal type I hypersensitivity reaction	FCGR1A FCGR1BP GAB2 GAB4	6.89e-05	84	37	4	MP:0002531
MousePheno	hemolytic anemia	FCGR1A FCGR1BP IL2RB	1.15e-04	36	37	3	MP:0001585
MousePheno	increased compact bone mass	GAB2 GAB4	1.42e-04	7	37	2	MP:0010961
MousePheno	abnormal mast cell differentiation	GAB2 GAB4	3.03e-04	10	37	2	MP:0005462
MousePheno	abnormal macrophage antigen presentation	FCGR1A FCGR1BP	3.03e-04	10	37	2	MP:0002454
MousePheno	decreased susceptibility to Ortervirales infection	GAB2 GAB4	4.42e-04	12	37	2	MP:0020920
MousePheno	decreased susceptibility to Retroviridae infection	GAB2 GAB4	4.42e-04	12	37	2	MP:0020935
MousePheno	total cataract	CRYBA2 NHS	5.22e-04	13	37	2	MP:0010263
Domain	ig	ADGRF5 PTPRD FCGR1A FCGR1BP CNTN2	8.14e-05	190	44	5	PF00047
Domain	Immunoglobulin	ADGRF5 PTPRD FCGR1A FCGR1BP CNTN2	8.14e-05	190	44	5	IPR013151
Domain	IGc2	ADGRF5 PTPRD FCGR1A FCGR1BP CNTN2	2.20e-04	235	44	5	SM00408
Domain	Ig_sub2	ADGRF5 PTPRD FCGR1A FCGR1BP CNTN2	2.20e-04	235	44	5	IPR003598
Domain	PDZ	PTPN13 RAPGEF6 MAST2 SHROOM2	3.34e-04	141	44	4	PF00595
Domain	PDZ	PTPN13 RAPGEF6 MAST2 SHROOM2	4.02e-04	148	44	4	SM00228
Domain	-	PTPN13 RAPGEF6 MAST2 SHROOM2	4.23e-04	150	44	4	2.30.42.10
Domain	PDZ	PTPN13 RAPGEF6 MAST2 SHROOM2	4.33e-04	151	44	4	PS50106
Domain	PDZ	PTPN13 RAPGEF6 MAST2 SHROOM2	4.44e-04	152	44	4	IPR001478
Domain	SEA	MUC16 ADGRF5	4.85e-04	14	44	2	SM00200
Domain	-	MUC16 ADGRF5	5.59e-04	15	44	2	3.30.70.960
Domain	-	ADGRF5 PTPRD FCGR1A FCGR1BP TNR IL2RB CNTN2	8.40e-04	663	44	7	2.60.40.10
Domain	FN3	PTPRD TNR IL2RB CNTN2	9.28e-04	185	44	4	SM00060
Domain	Ig-like_fold	ADGRF5 PTPRD FCGR1A FCGR1BP TNR IL2RB CNTN2	1.21e-03	706	44	7	IPR013783
Domain	SEA	MUC16 ADGRF5	1.22e-03	22	44	2	PF01390
Domain	FN3	PTPRD TNR IL2RB CNTN2	1.22e-03	199	44	4	PS50853
Domain	SEA	MUC16 ADGRF5	1.33e-03	23	44	2	PS50024
Domain	SEA_dom	MUC16 ADGRF5	1.33e-03	23	44	2	IPR000082
Domain	FN3_dom	PTPRD TNR IL2RB CNTN2	1.46e-03	209	44	4	IPR003961
Domain	S100_CABP	HRNR FLG2	1.83e-03	27	44	2	PS00303
Domain	S_100	HRNR FLG2	1.83e-03	27	44	2	PF01023
Domain	S100_Ca-bd_sub	HRNR FLG2	1.97e-03	28	44	2	IPR013787
Domain	S100/CaBP-9k_CS	HRNR FLG2	1.97e-03	28	44	2	IPR001751
Domain	S_100	HRNR FLG2	1.97e-03	28	44	2	SM01394
Domain	IG	ADGRF5 PTPRD FCGR1A FCGR1BP CNTN2	2.99e-03	421	44	5	SM00409
Domain	Ig_sub	ADGRF5 PTPRD FCGR1A FCGR1BP CNTN2	2.99e-03	421	44	5	IPR003599
Domain	PTPc	PTPN13 PTPRD	3.25e-03	36	44	2	SM00194
Domain	TYR_PHOSPHATASE_PTP	PTPN13 PTPRD	3.80e-03	39	44	2	PS50055
Domain	PTPase_domain	PTPN13 PTPRD	4.20e-03	41	44	2	IPR000242
Domain	Y_phosphatase	PTPN13 PTPRD	4.20e-03	41	44	2	PF00102
Domain	IG_LIKE	ADGRF5 PTPRD FCGR1A FCGR1BP CNTN2	5.74e-03	491	44	5	PS50835
Domain	Ig-like_dom	ADGRF5 PTPRD FCGR1A FCGR1BP CNTN2	6.35e-03	503	44	5	IPR007110
Domain	fn3	PTPRD TNR CNTN2	6.54e-03	162	44	3	PF00041
Domain	PTPc_motif	PTPN13 PTPRD	8.52e-03	59	44	2	SM00404
Domain	Tyr_Pase_cat	PTPN13 PTPRD	8.52e-03	59	44	2	IPR003595
Domain	UBA-like	TNRC6B UBAP2L	9.97e-03	64	44	2	IPR009060
Domain	Ig_I-set	ADGRF5 PTPRD CNTN2	1.01e-02	190	44	3	IPR013098
Domain	I-set	ADGRF5 PTPRD CNTN2	1.01e-02	190	44	3	PF07679
Pubmed	Microtubule-associated serine/threonine kinase-205 kDa and Fc gamma receptor control IL-12 p40 synthesis and NF-kappa B activation.	FCGR1A FCGR1BP MAST2	7.55e-08	7	46	3	14764729
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RBM7 NAV2 USP31 NHS AKAP11 PTPN13 RAPGEF6 ALPK1 MAST2 GAB2	1.49e-07	861	46	10	36931259
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	NAV2 TNRC6B AKAP11 ALPK1 THSD7A SMG7	5.18e-07	225	46	6	12168954
Pubmed	Single Nucleotide Polymorphisms of the High Affinity IgG Receptor FcγRI Reduce Immune Complex Binding and Downstream Effector Functions.	FCGR1A FCGR1BP	1.71e-06	2	46	2	28814603
Pubmed	FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo.	FCGR1A FCGR1BP	1.71e-06	2	46	2	8611682
Pubmed	Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined with rapamycin.	GAB2 GAB4	1.71e-06	2	46	2	20535152
Pubmed	G-CSF-dependent neutrophil differentiation requires downregulation of MAPK activities through the Gab2 signaling pathway.	GAB2 GAB4	1.71e-06	2	46	2	32437087
Pubmed	Inhibition of GAB2 expression has a protective effect on osteoarthritis:An in vitro and in vivo study.	GAB2 GAB4	1.71e-06	2	46	2	36007472
Pubmed	Direct targeting of genetically modified tumour cells to Fc gammaRI triggers potent tumour cytotoxicity.	FCGR1A FCGR1BP	1.71e-06	2	46	2	16409296
Pubmed	Features and protective efficacy of human mAbs targeting Mycobacterium tuberculosis arabinomannan.	FCGR1A FCGR1BP	1.71e-06	2	46	2	37733444
Pubmed	Modulating IgG effector function by Fc glycan engineering.	FCGR1A FCGR1BP	1.71e-06	2	46	2	28289219
Pubmed	Amelioration of Lupus Serum-Induced Skin Inflammation in CD64-Deficient Mice.	FCGR1A FCGR1BP	1.71e-06	2	46	2	35273604
Pubmed	A role for the scaffolding adapter GAB2 in breast cancer.	GAB2 GAB4	1.71e-06	2	46	2	16369543
Pubmed	Deletion of Gab2 in mice protects against hepatic steatosis and steatohepatitis: a novel therapeutic target for fatty liver disease.	GAB2 GAB4	1.71e-06	2	46	2	27282405
Pubmed	Gab2 deficiency suppresses high-fat diet-induced obesity by reducing adipose tissue inflammation and increasing brown adipose function in mice.	GAB2 GAB4	1.71e-06	2	46	2	33637697
Pubmed	IgG3-mediated enhancement of the antibody response is normal in Fc gammaRI-deficient mice.	FCGR1A FCGR1BP	1.71e-06	2	46	2	16305642
Pubmed	Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1.	FCGR1A FCGR1BP	1.71e-06	2	46	2	9257847
Pubmed	Fcγ receptor I alpha chain (CD64) expression in macrophages is critical for the onset of meningitis by Escherichia coli K1.	FCGR1A FCGR1BP	1.71e-06	2	46	2	21124939
Pubmed	Mouse FcgammaRI: identification and functional characterization of five new alleles.	FCGR1A FCGR1BP	1.71e-06	2	46	2	10752630
Pubmed	Macrophages eliminate circulating tumor cells after monoclonal antibody therapy.	FCGR1A FCGR1BP	1.71e-06	2	46	2	24430180
Pubmed	Fcγ Receptor Type I (CD64)-Mediated Impairment of the Capacity of Dendritic Cells to Activate Specific CD8 T Cells by IgG-opsonized Friend Virus.	FCGR1A FCGR1BP	1.71e-06	2	46	2	30744065
Pubmed	Serum anti-Fcgamma receptor autoantibodies in patients with alopecia areata.	FCGR1A FCGR1BP	1.71e-06	2	46	2	17124586
Pubmed	Docking protein Gab2 regulates mucin expression and goblet cell hyperplasia through TYK2/STAT6 pathway.	GAB2 GAB4	1.71e-06	2	46	2	22859374
Pubmed	Abnormal hematopoiesis in Gab2 mutant mice.	GAB2 GAB4	1.71e-06	2	46	2	17374739
Pubmed	Gads/Grb2-mediated association with LAT is critical for the inhibitory function of Gab2 in T cells.	GAB2 GAB4	1.71e-06	2	46	2	12640133
Pubmed	The pleckstrin homology domain of Gab-2 is required for optimal interleukin-3 signalsome-mediated responses.	GAB2 GAB4	1.71e-06	2	46	2	16275030
Pubmed	Gab2 plays distinct roles in bone homeostasis at different time points.	GAB2 GAB4	1.71e-06	2	46	2	17323176
Pubmed	Ligand-dependent dynamics and intramolecular signaling in a PDZ domain.	PTPN13 RAPGEF6	1.71e-06	2	46	2	14698303
Pubmed	Neuronal FcγRI mediates acute and chronic joint pain.	FCGR1A FCGR1BP	1.71e-06	2	46	2	31211699
Pubmed	Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity.	FCGR1A FCGR1BP	1.71e-06	2	46	2	38885133
Pubmed	Gab2 (Grb2-Associated Binder2) Plays a Crucial Role in Inflammatory Signaling and Endothelial Dysfunction.	GAB2 GAB4	1.71e-06	2	46	2	33827252
Pubmed	Linkage on chromosome 3 of autoimmune diabetes and defective Fc receptor for IgG in NOD mice.	FCGR1A FCGR1BP	1.71e-06	2	46	2	8480181
Pubmed	A novel role for Gab2 in bFGF-mediated cell survival during retinoic acid-induced neuronal differentiation.	GAB2 GAB4	1.71e-06	2	46	2	16009726
Pubmed	Energetics of peptide recognition by the second PDZ domain of human protein tyrosine phosphatase 1E.	PTPN13 RAPGEF6	1.71e-06	2	46	2	17240990
Pubmed	Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.	FCGR1A FCGR1BP	1.71e-06	2	46	2	29576375
Pubmed	Docking protein Gab2 positively regulates glycoprotein VI-mediated platelet activation.	GAB2 GAB4	1.71e-06	2	46	2	16198316
Pubmed	Growth factor receptor bound protein 2-associated binder 2, a scaffolding adaptor protein, negatively regulates host immunity against tuberculosis.	GAB2 GAB4	1.71e-06	2	46	2	24805943
Pubmed	Novel Fc gamma receptor I family gene products in human mononuclear cells.	FCGR1A FCGR1BP	1.71e-06	2	46	2	1430234
Pubmed	Radiation hybrid mapping of the genes for tenascin-R (TNR), phosducin (PDC), laminin C1 (LAMC1), and TAX in 1q25-q32.	TNR CNTN2	1.71e-06	2	46	2	9403076
Pubmed	Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.	MUC16 MUC4	1.71e-06	2	46	2	23544943
Pubmed	Role of Gab2 in mammary tumorigenesis and metastasis.	GAB2 GAB4	1.71e-06	2	46	2	17310989
Pubmed	The FcRgamma chain is not essential for induction of experimental allergic encephalomyelitis (EAE) or anti-myelin antibody-mediated exacerbation of EAE.	FCGR1A FCGR1BP	1.71e-06	2	46	2	15835266
Pubmed	Amelioration of crescentic glomerulonephritis by RhoA kinase inhibitor, Fasudil, through podocyte protection and prevention of leukocyte migration.	FCGR1A FCGR1BP	1.71e-06	2	46	2	18245810
Pubmed	Reconstitution of allogeneic hemopoietic stem cells: the essential role of FcR gamma and the TCR beta-chain-FCp33 complex.	FCGR1A FCGR1BP	1.71e-06	2	46	2	16849450
Pubmed	Regulation of the Erk2-Elk1 signaling pathway and megakaryocytic differentiation of Bcr-Abl(+) K562 leukemic cells by Gab2.	GAB2 GAB4	1.71e-06	2	46	2	11830491
Pubmed	Extracellular mutations of non-obese diabetic mouse FcgammaRI modify surface expression and ligand binding.	FCGR1A FCGR1BP	1.71e-06	2	46	2	8663283
Pubmed	The interaction of N-glycans in Fcγ receptor I α-chain with Escherichia coli K1 outer membrane protein A for entry into macrophages: experimental and computational analysis.	FCGR1A FCGR1BP	1.71e-06	2	46	2	25231998
Pubmed	Lentivirus-mediated knockdown of FcγRI (CD64) attenuated lupus nephritis via inhibition of NF-κB regulating NLRP3 inflammasome activation in MRL/lpr mice.	FCGR1A FCGR1BP	1.71e-06	2	46	2	30190171
Pubmed	Biochemical characterization of murine Fc gamma RI.	FCGR1A FCGR1BP	1.71e-06	2	46	2	8478020
Pubmed	FcγR-binding affinity of monoclonal murine IgG1s carrying different N-linked Fc oligosaccharides.	FCGR1A FCGR1BP	1.71e-06	2	46	2	31554601
Pubmed	Essential role for Gab2 in the allergic response.	GAB2 GAB4	1.71e-06	2	46	2	11449275
Pubmed	CD64 plays a key role in diabetic wound healing.	FCGR1A FCGR1BP	1.71e-06	2	46	2	38524127
Pubmed	Scaffolding protein Gab2 is involved in postnatal development and lipopolysaccharide-induced activation of microglia in the mouse brain.	GAB2 GAB4	1.71e-06	2	46	2	34146905
Pubmed	The absence of Grb2-associated binder 2 (Gab2) does not disrupt NK cell development and functions.	GAB2 GAB4	1.71e-06	2	46	2	15240750
Pubmed	Molecular cloning and expression of the mouse high affinity Fc receptor for IgG.	FCGR1A FCGR1BP	1.71e-06	2	46	2	2136886
Pubmed	Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation.	GAB2 GAB4	1.71e-06	2	46	2	9885561
Pubmed	Gene organization of the human high affinity receptor for IgG, Fc gamma RI (CD64). Characterization and evidence for a second gene.	FCGR1A FCGR1BP	1.71e-06	2	46	2	1830050
Pubmed	Grb2 associated binder 2 couples B-cell receptor to cell survival.	GAB2 GAB4	1.71e-06	2	46	2	18950707
Pubmed	FcRγ deficiency improves survival in experimental sepsis by down-regulating TLR4 signaling pathway.	FCGR1A FCGR1BP	1.71e-06	2	46	2	30552619
Pubmed	Liver-specific overexpression of Gab2 accelerates hepatocellular carcinoma progression by activating immunosuppression of myeloid-derived suppressor cells.	GAB2 GAB4	1.71e-06	2	46	2	35411035
Pubmed	Sensory Neuron Expressed FcγRI Mediates Postinflammatory Arthritis Pain in Female Mice.	FCGR1A FCGR1BP	1.71e-06	2	46	2	35833115
Pubmed	Gab2 is essential for Bcr-Abl-mediated leukemic transformation and hydronephrosis in a chronic myeloid leukemia mouse model.	GAB2 GAB4	1.71e-06	2	46	2	27125306
Pubmed	Gab2 promotes the growth of colorectal cancer by regulating the M2 polarization of tumor‑associated macrophages.	GAB2 GAB4	1.71e-06	2	46	2	37937666
Pubmed	Developmentally ordered appearance of a functional Fc gamma receptor on TCR V gamma 3 thymocytes. Evidence for stimulation-induced expression.	FCGR1A FCGR1BP	1.71e-06	2	46	2	8077658
Pubmed	Requirement of Gab2 for mast cell development and KitL/c-Kit signaling.	GAB2 GAB4	1.71e-06	2	46	2	11861309
Pubmed	Differential gene expression modulated by the cytoplasmic domain of Fc gamma RIa (CD64) alpha-chain.	FCGR1A FCGR1BP	1.71e-06	2	46	2	15528358
Pubmed	Solution structure of the PDZ2 domain from cytosolic human phosphatase hPTP1E complexed with a peptide reveals contribution of the beta2-beta3 loop to PDZ domain-ligand interactions.	PTPN13 RAPGEF6	1.71e-06	2	46	2	12095257
Pubmed	Functional characteristics of the high affinity IgG receptor, FcγRI.	FCGR1A FCGR1BP	1.71e-06	2	46	2	21325219
Pubmed	Fc receptors and the common gamma-chain in experimental autoimmune encephalomyelitis.	FCGR1A FCGR1BP	1.71e-06	2	46	2	14991835
Pubmed	Distinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1.	GAB2 GAB4	1.71e-06	2	46	2	26773044
Pubmed	Definition of interferon gamma-response elements in a novel human Fc gamma receptor gene (Fc gamma RIb) and characterization of the gene structure.	FCGR1A FCGR1BP	1.71e-06	2	46	2	1402657
Pubmed	The involvement of FcR mechanisms in antibody-mediated rejection.	FCGR1A FCGR1BP	1.71e-06	2	46	2	18049118
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SORCS2 ANKS1B USP31 ATP1A3 FCGR1A FCGR1BP SHROOM2 TNR DHX29 UBAP2L CNTN2	1.95e-06	1431	46	11	37142655
Pubmed	Residual LCMV antigen in transiently CD4+ T cell-depleted mice induces high levels of virus-specific antibodies but only limited B-cell memory.	FCGR1A FCGR1BP	5.13e-06	3	46	2	30636035
Pubmed	Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin.	HRNR FLG2	5.13e-06	3	46	2	23403047
Pubmed	The Gab2-MALT1 axis regulates thromboinflammation and deep vein thrombosis.	GAB2 GAB4	5.13e-06	3	46	2	35895897
Pubmed	Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria.	FCGR1A FCGR1BP	5.13e-06	3	46	2	16841095
Pubmed	Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.	MUC16 MUC4	5.13e-06	3	46	2	23053434
Pubmed	Nephrotoxic nephritis is mediated by Fcgamma receptors on circulating leukocytes and not intrinsic renal cells.	FCGR1A FCGR1BP	5.13e-06	3	46	2	12427132
Pubmed	Cutting Edge: Drebrin-Regulated Actin Dynamics Regulate IgE-Dependent Mast Cell Activation and Allergic Responses.	FCGR1A FCGR1BP	5.13e-06	3	46	2	26056254
Pubmed	The essential role of complement in antibody-mediated resistance to Salmonella.	FCGR1A FCGR1BP	5.13e-06	3	46	2	30179254
Pubmed	The three genes of the human FCGR1 gene family encoding Fc gamma RI flank the centromere of chromosome 1 at 1p12 and 1q21.	FCGR1A FCGR1BP	5.13e-06	3	46	2	8697799
Pubmed	Transcriptional and post-transcriptional regulation of IκB-ζ upon engagement of the BCR, TLRs and FcγR.	FCGR1A FCGR1BP	5.13e-06	3	46	2	23728777
Pubmed	MicroRNA-127 inhibits lung inflammation by targeting IgG Fcγ receptor I.	FCGR1A FCGR1BP	5.13e-06	3	46	2	22287715
Pubmed	Tpl2 kinase regulates FcγR signaling and immune thrombocytopenia in mice.	FCGR1A FCGR1BP	5.13e-06	3	46	2	23898046
Pubmed	FcγRI mediates serum amyloid P inhibition of fibrocyte differentiation.	FCGR1A FCGR1BP	5.13e-06	3	46	2	22493081
Pubmed	FcgammaR-induced production of superoxide and inflammatory cytokines is differentially regulated by SHIP through its influence on PI3K and/or Ras/Erk pathways.	FCGR1A FCGR1BP	5.13e-06	3	46	2	16543474
Pubmed	A germline gain-of-function mutation in Ptpn11 (Shp-2) phosphatase induces myeloproliferative disease by aberrant activation of hematopoietic stem cells.	GAB2 GAB4	5.13e-06	3	46	2	20651068
Pubmed	Escherichia coli K1 induces pterin production for enhanced expression of Fcγ receptor I to invade RAW 264.7 macrophages.	FCGR1A FCGR1BP	5.13e-06	3	46	2	24161960
Pubmed	Gab2 promotes colony-stimulating factor 1-regulated macrophage expansion via alternate effectors at different stages of development.	GAB2 GAB4	5.13e-06	3	46	2	21930791
Pubmed	Critical role for scaffolding adapter Gab2 in Fc gamma R-mediated phagocytosis.	GAB2 GAB4	5.13e-06	3	46	2	12821647
Pubmed	Comparative FISH mapping of Gab1 and Gab2 genes in human, mouse and rat.	GAB2 GAB4	5.13e-06	3	46	2	11701952
Pubmed	Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.	MUC16 MUC4	5.13e-06	3	46	2	30236127
Pubmed	Both Fcgamma receptor I and Fcgamma receptor III mediate disease in accelerated nephrotoxic nephritis.	FCGR1A FCGR1BP	5.13e-06	3	46	2	12707052
Pubmed	Stat3 promotes the development of erythroleukemia by inducing Pu.1 expression and inhibiting erythroid differentiation.	GAB2 GAB4	5.13e-06	3	46	2	19581930
Pubmed	Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.	MUC16 MUC4	5.13e-06	3	46	2	35879412
Pubmed	Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress.	GAB2 GAB4	5.13e-06	3	46	2	30816308
Pubmed	Serine phosphorylation of FcγRI cytoplasmic domain directs lipid raft localization and interaction with protein 4.1G.	FCGR1A FCGR1BP	5.13e-06	3	46	2	22003208
Pubmed	GRB2-mediated recruitment of GAB2, but not GAB1, to SF-STK supports the expansion of Friend virus-infected erythroid progenitor cells.	GAB2 GAB4	5.13e-06	3	46	2	16314834
Pubmed	FcgammaRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions.	FCGR1A FCGR1BP	5.13e-06	3	46	2	19657115
Interaction	SFN interactions	RBM7 NAV2 USP31 NHS AKAP11 PTPN13 RAPGEF6 MAST2 GAB2	1.84e-05	692	45	9	int:SFN
Interaction	YWHAB interactions	RBM7 MCC NAV2 USP31 NHS AKAP11 PTPN13 RAPGEF6 MAST2 GAB2	6.34e-05	1014	45	10	int:YWHAB
Interaction	YWHAG interactions	RBM7 MCC NAV2 USP31 NHS AKAP11 PTPN13 RAPGEF6 MAST2 SHROOM2 GAB2	7.07e-05	1248	45	11	int:YWHAG
Interaction	YWHAE interactions	RBM7 MCC NAV2 USP31 NHS AKAP11 PTPN13 RAPGEF6 MAST2 SHROOM2 GAB2	7.49e-05	1256	45	11	int:YWHAE
Cytoband	22q13.1	TNRC6B ENTHD1 IL2RB	8.78e-05	85	46	3	22q13.1
Cytoband	19q12	TSHZ3 ZNF536	1.84e-04	20	46	2	19q12
Cytoband	1q21.3	HRNR FLG2 UBAP2L	2.26e-04	117	46	3	1q21.3
Cytoband	Ensembl 112 genes in cytogenetic band chr19q12	TSHZ3 ZNF536	4.20e-04	30	46	2	chr19q12
Cytoband	Ensembl 112 genes in cytogenetic band chr1q21	HRNR FLG2 FCGR1A UBAP2L	7.20e-04	404	46	4	chr1q21
Cytoband	4p16.1	SORCS2 BLOC1S4	2.88e-03	79	46	2	4p16.1
GeneFamily	EF-hand domain containing\|S100 fused type protein family	HRNR FLG2	7.60e-05	7	35	2	1350
GeneFamily	PDZ domain containing	PTPN13 RAPGEF6 MAST2 SHROOM2	2.05e-04	152	35	4	1220
GeneFamily	Immunoglobulin like domain containing	ADGRF5 FCGR1A FCGR1BP CNTN2	5.09e-04	193	35	4	594
GeneFamily	CD molecules\|Mucins	MUC16 MUC4	7.47e-04	21	35	2	648
GeneFamily	Fibronectin type III domain containing	PTPRD TNR CNTN2	3.62e-03	160	35	3	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	ADGRF5 PTPRD CNTN2	3.68e-03	161	35	3	593
GeneFamily	EF-hand domain containing	MCC HRNR FLG2	8.62e-03	219	35	3	863
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SORCS2 NAV2 NHS PTPN13 PTPRD MUC4 FAM149A	6.85e-10	180	46	7	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	NAV2 ADGRF5 PTPN13 PTPRD MUC4 FAM149A	3.20e-08	181	46	6	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	NAV2 ADGRF5 PTPN13 PTPRD MUC4 FAM149A	3.64e-08	185	46	6	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ANKS1B USP31 ZNF536 PTPN13 PTPRD CNTN2	5.29e-08	197	46	6	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANKS1B MCC USP31 NHS TSHZ3 MUC4	5.29e-08	197	46	6	1e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell	nucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MCC USP31 NHS TSHZ3 MUC4	1.07e-06	177	46	5	cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCell	nucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MCC USP31 NHS TSHZ3 MUC4	1.07e-06	177	46	5	ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORCS2 NAV2 NHS ZNF536 PTPN13	1.23e-06	182	46	5	812ff2a50a510b18d865e89465dba1754a08ef61
ToppCell	COPD-Epithelial-Club\|World / Disease state, Lineage and Cell class	NAV2 ADGRF5 PTPN13 PTPRD MUC4	1.37e-06	186	46	5	3006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MCC NHS ZNF536 THSD7A ATP1A3	1.40e-06	187	46	5	ae2ee6f8e5c37cb88a67f3e742cf86e57657bfaf
ToppCell	COPD-Epithelial-Club\|COPD / Disease state, Lineage and Cell class	NAV2 ADGRF5 PTPN13 PTPRD MUC4	1.56e-06	191	46	5	c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NHS PTPN13 PTPRD MUC4 FAM149A	1.56e-06	191	46	5	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MCC NHS ZNF536 THSD7A ATP1A3	1.60e-06	192	46	5	3abee376c37c3646da33ac381aa63d50a01607a6
ToppCell	Control-Epithelial-Club\|Control / Disease state, Lineage and Cell class	NAV2 NHS ADGRF5 PTPN13 MUC4	1.60e-06	192	46	5	d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MCC NHS ZNF536 THSD7A ATP1A3	1.60e-06	192	46	5	bf1943715085c4124b1675888b0615c9500ec888
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	NAV2 PTPN13 PTPRD MUC4 FAM149A	1.64e-06	193	46	5	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ANKS1B ZNF536 PTPN13 PTPRD CNTN2	1.68e-06	194	46	5	cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MUC16 NHS PTPN13 MUC4 FAM149A	1.72e-06	195	46	5	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SORCS2 ADGRF5 PTPN13 MUC4 FAM149A	1.77e-06	196	46	5	ed76eeb37400ca154feae9b7ebaddb6c434f8b81
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SORCS2 NHS TSHZ3 ZNF536 PTPN13	1.81e-06	197	46	5	dfeb4a0eb4dfba90f4a3e6ba31e0ab0e4aba5849
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SORCS2 NHS TSHZ3 ZNF536 PTPN13	1.81e-06	197	46	5	ee8f7def9d5af7b1e636830a4ea1da158d02f25a
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NHS PTPN13 PTPRD MUC4 FAM149A	1.86e-06	198	46	5	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SORCS2 ANKS1B ZNF536 PTPRD CNTN2	1.90e-06	199	46	5	5d2e85e40b6b52b1809e680b952913d77215b3d0
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SORCS2 ANKS1B ZNF536 PTPRD CNTN2	1.90e-06	199	46	5	9dd4b17fb8c70ab9e126b23b72600463f3db832d
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SORCS2 ANKS1B ZNF536 PTPRD CNTN2	1.90e-06	199	46	5	6fb5f931e6217142de38c1fffc011e63bda4772b
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SORCS2 ANKS1B ZNF536 PTPRD CNTN2	1.90e-06	199	46	5	1bb5797e8e0552bf9b44bf4c958d1aa6dbe6c756
ToppCell	Neuronal-Inhibitory\|Neuronal / cells hierarchy compared to all cells using T-Statistic	MCC NHS ZNF536 THSD7A ATP1A3	1.95e-06	200	46	5	9ff8647e2de0b538e15929dca88ebb20ff7ab043
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MCC USP31 NHS TSHZ3 MUC4	1.95e-06	200	46	5	8827653738a931e4a4545e0c7d75be12bed40740
ToppCell	Basal_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	MCC NHS TSHZ3 ATP1A3	2.41e-05	163	46	4	679e25e5548d157d49a73057a3b5617dccda260f
ToppCell	Control-Epithelial_cells-Airway_basal\|Control / group, cell type (main and fine annotations)	MCC USP31 TSHZ3 MUC4	2.90e-05	171	46	4	3965ced4be6db14265a90673502fceee425837ca
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 PTPN13 THSD7A IL2RB	3.04e-05	173	46	4	d17e50dc400098374af626803dec1241ec566769
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORCS2 NHS ADGRF5 SHROOM2	3.25e-05	176	46	4	7292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122\|Adult / Lineage, Cell type, age group and donor	SORCS2 PTPN13 MUC4 FAM149A	3.25e-05	176	46	4	3fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORCS2 NHS ADGRF5 SHROOM2	3.25e-05	176	46	4	88ca2f83d8301633232735f39b0683efe49d0b86
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MCC NHS ZNF536 THSD7A	3.32e-05	177	46	4	fdab7b7ddfb06f913b8224c0c80574dc3cf4cbd4
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAV2 PTPN13 THSD7A IL2RB	3.39e-05	178	46	4	888add8935ef3aef9b6693c5698e9d1842e66337
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAV2 PTPN13 THSD7A IL2RB	3.39e-05	178	46	4	43eda32af2e5e28a92421612d0a4c21e5427a772
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SORCS2 PTPN13 THSD7A FAM149A	3.39e-05	178	46	4	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MCC NHS ZNF536 THSD7A	3.47e-05	179	46	4	3b0f8781232e1d42b6f8913bc989a14b3f978e79
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORCS2 NAV2 ZNF536 PTPN13	3.55e-05	180	46	4	d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORCS2 NAV2 ZNF536 PTPN13	3.55e-05	180	46	4	dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCell	5'-Adult-Appendix-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANKS1B ZNF536 PTPN13 CNTN2	3.62e-05	181	46	4	3aa81ac64d0cc9a74fbfa71e2176740548e7cd06
ToppCell	5'-Adult-Appendix-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANKS1B ZNF536 PTPN13 CNTN2	3.62e-05	181	46	4	997ba1be2824b00d684f2163d0114656ed11fa53
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MCC NHS ZNF536 THSD7A	3.62e-05	181	46	4	7704f236831cffe4f2a75d4c461eb88b4177e206
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MCC NHS ZNF536 THSD7A	3.62e-05	181	46	4	153709b4dd3d81e09f251fa8765b58bed1932fda
ToppCell	10x5'-bone_marrow-Mast-Mast_cell_lympho\|bone_marrow / Manually curated celltypes from each tissue	CPEB3 ALPK1 THSD7A GAB2	3.62e-05	181	46	4	56fa77ae31f3b7de6e441a439c33a11353b6573a
ToppCell	5'-Adult-Appendix-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANKS1B ZNF536 PTPN13 CNTN2	3.62e-05	181	46	4	e6b7e8dd5c13cc10ba22f2f5a8c669486f934bdc
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MCC NHS ZNF536 THSD7A	3.70e-05	182	46	4	7dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCell	Control-Epithelial-Basal\|World / Disease state, Lineage and Cell class	MCC USP31 NHS PTPN13	3.70e-05	182	46	4	759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MCC NHS ZNF536 THSD7A	3.70e-05	182	46	4	420a8fd30543e37a66ba0786215d056d308660d0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MCC PTPN13 PTPRD THSD7A	3.78e-05	183	46	4	3c516fe5083f02bad1f464ed284010b4131a833c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MCC PTPN13 PTPRD THSD7A	3.78e-05	183	46	4	9c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SORCS2 MCC PTPN13 THSD7A	3.78e-05	183	46	4	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MCC PTPN13 PTPRD THSD7A	3.86e-05	184	46	4	7294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NHS ZNF536 THSD7A ATP1A3	3.95e-05	185	46	4	16e9ccea0e3b95d90dc48ef74206c805681dac0b
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	SORCS2 PTPN13 MUC4 FAM149A	3.95e-05	185	46	4	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SORCS2 PTPN13 THSD7A FAM149A	3.95e-05	185	46	4	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	Control-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	MCC USP31 NHS TSHZ3	3.95e-05	185	46	4	d5d6d13e2f20b54ca55645b9a757b8599f4fd897
ToppCell	Control-Epithelial-Club\|World / Disease state, Lineage and Cell class	NAV2 ADGRF5 PTPN13 MUC4	4.03e-05	186	46	4	9798428691408e17ff2af2fe2d1b345f074d67e4
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NAV2 ADGRF5 PTPN13 PTPRD	4.03e-05	186	46	4	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SORCS2 NAV2 NHS PTPRD	4.11e-05	187	46	4	5258674d0346e5c51a4b965efcdc1790c970845d
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	NHS PTPRD MUC4 FAM149A	4.11e-05	187	46	4	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	SORCS2 ADGRF5 PTPN13 FAM149A	4.11e-05	187	46	4	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TSHZ3 PTPN13 PTPRD THSD7A	4.11e-05	187	46	4	a9316e2818217ec5feae9cf8816f7249803caee6
ToppCell	COVID-19-Epithelial_cells-Airway_basal\|COVID-19 / group, cell type (main and fine annotations)	MCC NHS PTPN13 MUC4	4.11e-05	187	46	4	8407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MCC NHS ZNF536 THSD7A	4.20e-05	188	46	4	6ee3f8f94ea7bdf652c9575fc65bff08070093a4
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	NAV2 ADGRF5 PTPN13 MUC4	4.20e-05	188	46	4	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MCC NHS ZNF536 THSD7A	4.20e-05	188	46	4	72cbfe9dc0583dbeafa6cb0945fa370d0c808284
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SORCS2 NAV2 NHS ZNF536	4.20e-05	188	46	4	3004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MCC ADGRF5 SHROOM2 TNR	4.29e-05	189	46	4	b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	CPEB3 SORCS2 PTPN13 THSD7A	4.29e-05	189	46	4	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	IPF-Epithelial-Club\|IPF / Disease state, Lineage and Cell class	NAV2 ADGRF5 PTPN13 MUC4	4.29e-05	189	46	4	f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCell	IPF-Epithelial-Basal\|IPF / Disease state, Lineage and Cell class	MCC USP31 NHS PTPN13	4.38e-05	190	46	4	ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SORCS2 ADGRF5 PTPN13 THSD7A	4.38e-05	190	46	4	b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SORCS2 NAV2 NHS CENPI	4.38e-05	190	46	4	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SORCS2 ADGRF5 PTPN13 PTPRD	4.47e-05	191	46	4	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NHS ZNF536 THSD7A ATP1A3	4.47e-05	191	46	4	764c3a8829ae1253a0790744138266e81fc075ec
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SORCS2 ADGRF5 PTPN13 PTPRD	4.47e-05	191	46	4	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	IPF-Epithelial-Club\|World / Disease state, Lineage and Cell class	NAV2 ADGRF5 PTPN13 MUC4	4.47e-05	191	46	4	3c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_GGH\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MCC NHS ZNF536 THSD7A	4.47e-05	191	46	4	06760c3bb40e4f66879a5f5e09c9abfce4ebbba3
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NHS ZNF536 THSD7A ATP1A3	4.56e-05	192	46	4	025fac36b862f9ca7f96fb4a1946c44ba7cbc382
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MCC NHS ZNF536 THSD7A	4.56e-05	192	46	4	6a252e298f8a454623fa9c1c893a7a45a886d694
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	MCC USP31 NHS PTPN13	4.56e-05	192	46	4	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SORCS2 ADGRF5 PTPN13 PTPRD	4.56e-05	192	46	4	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ANKS1B ZNF536 PTPRD CNTN2	4.56e-05	192	46	4	3ce5dbde41aeb73d49f2c7991d34682f0827fa5a
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NHS ZNF536 THSD7A ATP1A3	4.65e-05	193	46	4	9f9eb241b0b82a6f12de6921c3acf6fed7cf65bb
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ANKS1B PTPN13 PTPRD CNTN2	4.65e-05	193	46	4	947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	SORCS2 MCC TSHZ3 THSD7A	4.65e-05	193	46	4	194e7fa00a50cc4e026987b715323d125d79594e
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ANKS1B TSHZ3 PTPRD THSD7A	4.75e-05	194	46	4	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NAV2 NHS ZNF536 CENPI	4.75e-05	194	46	4	590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SORCS2 ADGRF5 PTPN13 PTPRD	4.75e-05	194	46	4	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NHS ZNF536 THSD7A ATP1A3	4.75e-05	194	46	4	4f758718a1233c25c25d99fc1b7b06f906b8b0a2
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MCC NHS ZNF536 ATP1A3	4.75e-05	194	46	4	02a9cc821c2b14aa7d0e55661a5fab66364474e1
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RAPGEF6 IL2RB HCP5 NUP210	4.84e-05	195	46	4	83c125223e7ca0f08a31414b3a16347912564765
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MUC16 PTPRD FLG2 GAB4	4.84e-05	195	46	4	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MUC16 PTPRD FLG2 GAB4	4.84e-05	195	46	4	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ANKS1B TSHZ3 PTPRD THSD7A	4.84e-05	195	46	4	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PTPN13 PTPRD THSD7A FAM149A	4.84e-05	195	46	4	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	Tracheal-10x5prime-Stromal-Schwann\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ENTHD1 ZNF536 CNTN2 GAB4	4.94e-05	196	46	4	b6226163d9fc93ecfff2115bb74408303a000490
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MCC NHS ZNF536 ATP1A3	4.94e-05	196	46	4	7af6c5147ac859353504d19727dbe24f63a29dd4
Disease	decreased susceptibility to hepatitis C infection	NAV2 PTPRD	2.46e-04	16	43	2	EFO_0010101
Disease	tuberculosis	PTPRD THSD7A TNR IL2RB	2.76e-04	216	43	4	MONDO_0018076
Disease	Nuclear cataract	CRYBA2 NHS	3.13e-04	18	43	2	C0392557
Disease	Tourette syndrome, schizophrenia	ENTHD1 ZNF536	3.13e-04	18	43	2	EFO_0004895, MONDO_0005090
Disease	Nuclear non-senile cataract	CRYBA2 NHS	3.13e-04	18	43	2	C1112705
Disease	polymyositis	THSD7A HCP5	3.88e-04	20	43	2	EFO_0003063
Disease	severe acute respiratory syndrome, COVID-19	SORCS2 PTPRD THSD7A TNR NUP210	4.67e-04	447	43	5	EFO_0000694, MONDO_0100096
Disease	hippocampal sclerosis of aging	SORCS2 THSD7A	5.15e-04	23	43	2	EFO_0005678
Disease	retinal degeneration (biomarker_via_orthology)	FCGR1A FCGR1BP	7.65e-04	28	43	2	DOID:8466 (biomarker_via_orthology)
Disease	Ovarian Mucinous Adenocarcinoma	ALPK1 MAST2	9.39e-04	31	43	2	C1335167
Disease	eicosapentaenoic acid measurement	NAV2 TSHZ3	9.39e-04	31	43	2	EFO_0007760
Disease	red blood cell density measurement	SORCS2 TNRC6B ADGRF5 MAST2 MUC4 CNTN2	1.64e-03	880	43	6	EFO_0007978
Disease	chronotype measurement	CPEB3 USP31 TNRC6B TSHZ3 ZNF536 PTPRD	1.66e-03	882	43	6	EFO_0008328
Disease	waist-hip ratio	CPEB3 MCC TNRC6B ADGRF5 PTPRD FCGR1BP CNTN2	1.83e-03	1226	43	7	EFO_0004343
Disease	FEV/FEC ratio	ANKS1B MCC NAV2 TSHZ3 BLOC1S4 CNTN2 GAB2	1.84e-03	1228	43	7	EFO_0004713
Disease	aspartate aminotransferase measurement	RAPGEF6 PTPRD THSD7A BAZ2A CNTN2 GAB2	1.88e-03	904	43	6	EFO_0004736
Disease	platelet aggregation	PTPRD HCP5	1.97e-03	45	43	2	GO_0070527
Disease	disease progression measurement, Crohn's disease	SORCS2 PTPRD	2.15e-03	47	43	2	EFO_0000384, EFO_0008336
Disease	myeloid white cell count	MCC AKAP11 ADGRF5 ATP1A3 MAST2 TNR	2.26e-03	937	43	6	EFO_0007988
Disease	antibody measurement	ZNF536 PTPRD	2.34e-03	49	43	2	EFO_0004556
Disease	Hepatic fibrosis	SORCS2 TNR	2.34e-03	49	43	2	HP_0001395
Disease	Tourette syndrome	MUC16 THSD7A	2.43e-03	50	43	2	EFO_0004895
Disease	urate measurement, spine bone mineral density	NAV2 PTPRD	3.26e-03	58	43	2	EFO_0004531, EFO_0007701
Disease	response to opioid	MUC16 TNR	3.59e-03	61	43	2	EFO_0008541
Disease	age at diagnosis, type 1 diabetes mellitus	USP31 HCP5	3.71e-03	62	43	2	EFO_0004918, MONDO_0005147
Disease	cigarettes per day measurement	CPEB3 ZNF536 PTPRD THSD7A	3.74e-03	438	43	4	EFO_0006525

Protein segments in the cluster

Peptide	Gene	Start	Entry
WSGDSGTVSQSHSSA	BLOC1S4	26	Q9NUP1
SWLSQTQSHSSLLSS	BAZ2A	1271	Q9UIF9
WSGSSSHNSNQLLSF	CRYBA2	81	P53672
SFHHLSESNGNSSSW	AKAP11	1751	Q9UKA4
SSSTTSTSWEGNRAS	DHX29	1191	Q7Z478
GSQTSSAWSNLSGFS	ALPK1	576	Q96QP1
QSASGSSAWSTVFRH	SLC25A32	6	Q9H2D1
WSESSTAEHSSKGNS	ANKS1B	756	Q7Z6G8
GSGNFSWSSSSHLVA	NUP210	481	Q8TEM1
SHISSSHWGEFSTQN	ENTHD1	506	Q8IYW4
SSSTQWFLNGTATQT	FCGR1BP	51	Q92637
TWDTSITTSQAGTHS	MUC16	6461	Q8WXI7
SSSTASWPGTHSATT	MUC16	9386	Q8WXI7
TSASSQNHWTRSTQT	MUC4	191	Q99102
ISNSHLSWSTDSTAN	FLG2	2371	Q5D862
TGAHTSWSGSATQSS	FAM149A	241	A5PLN7
SWSGSATQSSTTGSS	FAM149A	246	A5PLN7
ETNSTSNSSHSAWDL	KCNK4	76	Q9NYG8
SSSWQSSGCTQHGSG	HRNR	1406	Q86YZ3
SSHASSWGSGSITCA	HCP5	76	Q6MZN7
QPWESLSSNSHTSTT	MCC	536	P23508
AAAAASSASSSWNTH	CPEB3	231	Q8NE35
SSASSSWNTHQSVNA	CPEB3	236	Q8NE35
WSGTSHTFDSSSSQH	GAB4	456	Q2WGN9
TSWASAAVNGTSQFT	IL2RB	21	P14784
SSSAWSSALGSQTTF	CNTN2	21	Q02246
HTSNSSQWNTSFASF	MS4A18	126	Q3C1V0
SSSVHSSVGQVTWQS	MAST2	116	Q6P0Q8
QSGTSFDKSSHTWVA	ATP1A3	396	P13637
SSSTQWFLNGTATQT	FCGR1A	51	P12314
TSQGSSSFQTTLSAW	CENPI	16	Q92674
SNSTWSSALHQTLSN	PTPN13	1671	Q12923
HSEGTTSTSVQLSWQ	PTPRD	926	P23468
TKSWSRANHTFNSSS	GAB2	546	Q9UQC2
SHSHSFNQSSSSQWR	RBM7	176	Q9Y580
GRGSWTSCSSSSHDN	RAPGEF6	1361	Q8TEU7
TSVSSFNTTTTWNGE	THSD7A	711	Q9UPZ6
DHQSSSGNWSGSSST	NHS	626	Q6T4R5
SSESSWHQASTPSGT	SMG7	1066	Q92540
SAHSAPSNSLTWGTN	NAV2	1396	Q8IVL1
DEGLTWSTHNFTSTS	SORCS2	591	Q96PQ0
SSSHDLSSSWEQTNL	SHROOM2	151	Q13796
WSSQHSKSTSLGSST	ADGRF5	1286	Q8IZF2
AAQHSQSGSTTTSSW	UBAP2L	376	Q14157
HFSHVTSSSVNITWS	TNR	781	Q92752
SSSSCGSGSFDWHQS	TSHZ3	156	Q63HK5
SQQWTSGVLSSGDHS	ZNF536	856	O15090
WSANSSVAGSTSSSL	USP31	771	Q70CQ4
WNTTGSQGSASSHNS	TNRC6B	1021	Q9UPQ9
SQGSASSHNSASWGQ	TNRC6B	1026	Q9UPQ9
TWSHSQSSDTIVSDG	KIAA1522	356	Q9P206