| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | calcium-dependent cysteine-type endopeptidase activity | 1.11e-07 | 17 | 54 | 4 | GO:0004198 | |
| GeneOntologyMolecularFunction | voltage-gated sodium channel activity | 6.83e-07 | 26 | 54 | 4 | GO:0005248 | |
| GeneOntologyMolecularFunction | Rho-dependent protein serine/threonine kinase activity | 7.18e-06 | 2 | 54 | 2 | GO:0072518 | |
| GeneOntologyMolecularFunction | sodium channel activity | 1.17e-05 | 52 | 54 | 4 | GO:0005272 | |
| GeneOntologyMolecularFunction | cysteine-type endopeptidase activity | 8.61e-05 | 86 | 54 | 4 | GO:0004197 | |
| GeneOntologyMolecularFunction | voltage-gated sodium channel activity involved in cardiac muscle cell action potential | 1.07e-04 | 6 | 54 | 2 | GO:0086006 | |
| GeneOntologyMolecularFunction | endopeptidase activity | 1.51e-04 | 430 | 54 | 7 | GO:0004175 | |
| GeneOntologyMolecularFunction | calcium ion binding | 8.53e-04 | 749 | 54 | 8 | GO:0005509 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential | 9.51e-04 | 17 | 54 | 2 | GO:0099508 | |
| GeneOntologyMolecularFunction | sodium ion transmembrane transporter activity | 1.18e-03 | 171 | 54 | 4 | GO:0015081 | |
| GeneOntologyMolecularFunction | tau-protein kinase activity | 1.60e-03 | 22 | 54 | 2 | GO:0050321 | |
| GeneOntologyMolecularFunction | cysteine-type peptidase activity | 1.80e-03 | 192 | 54 | 4 | GO:0008234 | |
| GeneOntologyMolecularFunction | peptidase activity | 1.82e-03 | 654 | 54 | 7 | GO:0008233 | |
| GeneOntologyMolecularFunction | monoatomic cation channel activity | 2.31e-03 | 343 | 54 | 5 | GO:0005261 | |
| GeneOntologyBiologicalProcess | transmission of nerve impulse | 4.18e-07 | 112 | 53 | 6 | GO:0019226 | |
| GeneOntologyBiologicalProcess | neuronal action potential | 5.80e-07 | 63 | 53 | 5 | GO:0019228 | |
| GeneOntologyBiologicalProcess | membrane depolarization during action potential | 2.15e-06 | 36 | 53 | 4 | GO:0086010 | |
| GeneOntologyBiologicalProcess | cell-cell junction assembly | 4.31e-06 | 167 | 53 | 6 | GO:0007043 | |
| GeneOntologyBiologicalProcess | blood circulation | 5.03e-06 | 648 | 53 | 10 | GO:0008015 | |
| GeneOntologyBiologicalProcess | action potential | 1.25e-05 | 201 | 53 | 6 | GO:0001508 | |
| GeneOntologyBiologicalProcess | circulatory system process | 1.48e-05 | 733 | 53 | 10 | GO:0003013 | |
| GeneOntologyBiologicalProcess | actin-mediated cell contraction | 1.85e-05 | 127 | 53 | 5 | GO:0070252 | |
| GeneOntologyBiologicalProcess | neuromuscular junction development, skeletal muscle fiber | 1.94e-05 | 3 | 53 | 2 | GO:0098529 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell action potential involved in contraction | 1.94e-05 | 62 | 53 | 4 | GO:0086002 | |
| GeneOntologyBiologicalProcess | neuromuscular process controlling posture | 2.38e-05 | 22 | 53 | 3 | GO:0050884 | |
| GeneOntologyBiologicalProcess | regulation of angiotensin-activated signaling pathway | 3.87e-05 | 4 | 53 | 2 | GO:0110061 | |
| GeneOntologyBiologicalProcess | cell-cell junction organization | 3.89e-05 | 246 | 53 | 6 | GO:0045216 | |
| GeneOntologyBiologicalProcess | actin filament-based movement | 4.53e-05 | 153 | 53 | 5 | GO:0030048 | |
| GeneOntologyBiologicalProcess | protein localization to juxtaparanode region of axon | 6.45e-05 | 5 | 53 | 2 | GO:0071205 | |
| GeneOntologyBiologicalProcess | regulation of synapse maturation | 6.84e-05 | 31 | 53 | 3 | GO:0090128 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell action potential | 7.38e-05 | 87 | 53 | 4 | GO:0086001 | |
| GeneOntologyBiologicalProcess | apical junction assembly | 8.43e-05 | 90 | 53 | 4 | GO:0043297 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell contraction | 9.58e-05 | 93 | 53 | 4 | GO:0086003 | |
| GeneOntologyBiologicalProcess | developmental maturation | 1.25e-04 | 439 | 53 | 7 | GO:0021700 | |
| GeneOntologyBiologicalProcess | negative regulation of bicellular tight junction assembly | 1.35e-04 | 7 | 53 | 2 | GO:1903347 | |
| GeneOntologyBiologicalProcess | bundle of His cell action potential | 1.35e-04 | 7 | 53 | 2 | GO:0086043 | |
| GeneOntologyBiologicalProcess | bundle of His cell to Purkinje myocyte signaling | 1.35e-04 | 7 | 53 | 2 | GO:0086028 | |
| GeneOntologyBiologicalProcess | membrane depolarization | 2.64e-04 | 121 | 53 | 4 | GO:0051899 | |
| GeneOntologyBiologicalProcess | response to interleukin-6 | 2.71e-04 | 49 | 53 | 3 | GO:0070741 | |
| GeneOntologyBiologicalProcess | regulation of atrial cardiac muscle cell membrane depolarization | 2.88e-04 | 10 | 53 | 2 | GO:0060371 | |
| GeneOntologyBiologicalProcess | synapse maturation | 2.88e-04 | 50 | 53 | 3 | GO:0060074 | |
| GeneOntologyBiologicalProcess | response to angiotensin | 2.88e-04 | 50 | 53 | 3 | GO:1990776 | |
| GeneOntologyBiologicalProcess | protein localization to axon | 3.51e-04 | 11 | 53 | 2 | GO:0099612 | |
| GeneOntologyBiologicalProcess | action potential propagation | 4.21e-04 | 12 | 53 | 2 | GO:0098870 | |
| GeneOntologyBiologicalProcess | neuronal action potential propagation | 4.21e-04 | 12 | 53 | 2 | GO:0019227 | |
| GeneOntologyBiologicalProcess | AV node cell to bundle of His cell signaling | 4.21e-04 | 12 | 53 | 2 | GO:0086027 | |
| GeneOntologyBiologicalProcess | AV node cell action potential | 4.21e-04 | 12 | 53 | 2 | GO:0086016 | |
| GeneOntologyBiologicalProcess | response to mechanical stimulus | 4.25e-04 | 247 | 53 | 5 | GO:0009612 | |
| GeneOntologyBiologicalProcess | detection of mechanical stimulus involved in sensory perception | 4.25e-04 | 57 | 53 | 3 | GO:0050974 | |
| GeneOntologyBiologicalProcess | regulation of cell-substrate adhesion | 4.82e-04 | 254 | 53 | 5 | GO:0010810 | |
| GeneOntologyBiologicalProcess | positive regulation of connective tissue replacement | 4.96e-04 | 13 | 53 | 2 | GO:1905205 | |
| GeneOntologyBiologicalProcess | regulation of system process | 5.32e-04 | 734 | 53 | 8 | GO:0044057 | |
| GeneOntologyBiologicalProcess | regulation of membrane potential | 5.41e-04 | 559 | 53 | 7 | GO:0042391 | |
| GeneOntologyBiologicalProcess | muscle contraction | 5.45e-04 | 400 | 53 | 6 | GO:0006936 | |
| GeneOntologyBiologicalProcess | positive regulation of integrin-mediated signaling pathway | 5.78e-04 | 14 | 53 | 2 | GO:2001046 | |
| GeneOntologyBiologicalProcess | left/right axis specification | 5.78e-04 | 14 | 53 | 2 | GO:0070986 | |
| GeneOntologyBiologicalProcess | positive regulation of cell-substrate adhesion | 5.82e-04 | 149 | 53 | 4 | GO:0010811 | |
| GeneOntologyBiologicalProcess | cell-substrate adhesion | 6.20e-04 | 410 | 53 | 6 | GO:0031589 | |
| GeneOntologyBiologicalProcess | cell-matrix adhesion | 6.36e-04 | 270 | 53 | 5 | GO:0007160 | |
| GeneOntologyBiologicalProcess | bundle of His cell to Purkinje myocyte communication | 6.66e-04 | 15 | 53 | 2 | GO:0086069 | |
| GeneOntologyBiologicalProcess | AV node cell to bundle of His cell communication | 6.66e-04 | 15 | 53 | 2 | GO:0086067 | |
| GeneOntologyBiologicalProcess | positive regulation of cell adhesion | 6.66e-04 | 579 | 53 | 7 | GO:0045785 | |
| GeneOntologyBiologicalProcess | amyloid-beta metabolic process | 7.45e-04 | 69 | 53 | 3 | GO:0050435 | |
| GeneOntologyBiologicalProcess | cardiac muscle contraction | 8.91e-04 | 167 | 53 | 4 | GO:0060048 | |
| GeneOntologyBiologicalProcess | detection of mechanical stimulus | 9.49e-04 | 75 | 53 | 3 | GO:0050982 | |
| GeneOntologyBiologicalProcess | regulation of connective tissue replacement | 9.65e-04 | 18 | 53 | 2 | GO:1905203 | |
| GeneOntologyBiologicalProcess | positive regulation of action potential | 9.65e-04 | 18 | 53 | 2 | GO:0045760 | |
| GeneOntologyBiologicalProcess | establishment of cell polarity | 1.11e-03 | 177 | 53 | 4 | GO:0030010 | |
| GeneOntologyBiologicalProcess | bicellular tight junction assembly | 1.19e-03 | 81 | 53 | 3 | GO:0070830 | |
| GeneOntologyBiologicalProcess | regulation of endothelial cell development | 1.19e-03 | 20 | 53 | 2 | GO:1901550 | |
| GeneOntologyBiologicalProcess | regulation of establishment of endothelial barrier | 1.19e-03 | 20 | 53 | 2 | GO:1903140 | |
| GeneOntologyBiologicalProcess | regulation of muscle system process | 1.30e-03 | 317 | 53 | 5 | GO:0090257 | |
| GeneOntologyBiologicalProcess | tight junction assembly | 1.51e-03 | 88 | 53 | 3 | GO:0120192 | |
| GeneOntologyBiologicalProcess | regulation of integrin-mediated signaling pathway | 1.58e-03 | 23 | 53 | 2 | GO:2001044 | |
| GeneOntologyBiologicalProcess | positive regulation of vascular permeability | 1.58e-03 | 23 | 53 | 2 | GO:0043117 | |
| GeneOntologyBiologicalProcess | dendrite development | 1.66e-03 | 335 | 53 | 5 | GO:0016358 | |
| GeneOntologyBiologicalProcess | dendrite morphogenesis | 1.67e-03 | 198 | 53 | 4 | GO:0048813 | |
| GeneOntologyBiologicalProcess | regulation of anatomical structure morphogenesis | 1.69e-03 | 1090 | 53 | 9 | GO:0022603 | |
| GeneOntologyBiologicalProcess | angiotensin-activated signaling pathway | 1.72e-03 | 24 | 53 | 2 | GO:0038166 | |
| GeneOntologyBiologicalProcess | regulation of heterochromatin formation | 1.72e-03 | 24 | 53 | 2 | GO:0031445 | |
| GeneOntologyBiologicalProcess | positive regulation of tissue remodeling | 1.72e-03 | 24 | 53 | 2 | GO:0034105 | |
| GeneOntologyBiologicalProcess | tight junction organization | 1.82e-03 | 94 | 53 | 3 | GO:0120193 | |
| GeneOntologyBiologicalProcess | vascular process in circulatory system | 1.87e-03 | 344 | 53 | 5 | GO:0003018 | |
| GeneOntologyBiologicalProcess | regulation of establishment of cell polarity | 1.87e-03 | 25 | 53 | 2 | GO:2000114 | |
| GeneOntologyBiologicalProcess | cerebellar Purkinje cell layer morphogenesis | 1.87e-03 | 25 | 53 | 2 | GO:0021692 | |
| GeneOntologyBiologicalProcess | sodium ion transmembrane transport | 2.00e-03 | 208 | 53 | 4 | GO:0035725 | |
| GeneOntologyBiologicalProcess | connective tissue replacement | 2.02e-03 | 26 | 53 | 2 | GO:0097709 | |
| GeneOntologyCellularComponent | voltage-gated sodium channel complex | 9.95e-08 | 17 | 55 | 4 | GO:0001518 | |
| GeneOntologyCellularComponent | sodium channel complex | 9.70e-07 | 29 | 55 | 4 | GO:0034706 | |
| GeneOntologyCellularComponent | paranodal junction | 3.68e-04 | 11 | 55 | 2 | GO:0033010 | |
| GeneOntologyCellularComponent | cation channel complex | 3.79e-04 | 235 | 55 | 5 | GO:0034703 | |
| GeneOntologyCellularComponent | presynaptic active zone | 5.18e-04 | 141 | 55 | 4 | GO:0048786 | |
| GeneOntologyCellularComponent | cell-cell junction | 8.72e-04 | 591 | 55 | 7 | GO:0005911 | |
| GeneOntologyCellularComponent | paranode region of axon | 9.01e-04 | 17 | 55 | 2 | GO:0033270 | |
| GeneOntologyCellularComponent | main axon | 1.67e-03 | 89 | 55 | 3 | GO:0044304 | |
| GeneOntologyCellularComponent | endoplasmic reticulum lumen | 1.78e-03 | 332 | 55 | 5 | GO:0005788 | |
| Domain | Na_channel_asu | 1.20e-08 | 10 | 53 | 4 | IPR001696 | |
| Domain | Na_trans_assoc | 1.20e-08 | 10 | 53 | 4 | IPR010526 | |
| Domain | Na_trans_assoc | 1.20e-08 | 10 | 53 | 4 | PF06512 | |
| Domain | Calpain_III | 2.81e-08 | 12 | 53 | 4 | IPR022683 | |
| Domain | calpain_III | 2.81e-08 | 12 | 53 | 4 | SM00720 | |
| Domain | C2_III | 2.81e-08 | 12 | 53 | 4 | IPR033883 | |
| Domain | Calpain_domain_III | 4.05e-08 | 13 | 53 | 4 | IPR022682 | |
| Domain | Calpain_III | 4.05e-08 | 13 | 53 | 4 | PF01067 | |
| Domain | Calpain_cysteine_protease | 5.66e-08 | 14 | 53 | 4 | IPR022684 | |
| Domain | CysPc | 7.71e-08 | 15 | 53 | 4 | SM00230 | |
| Domain | Peptidase_C2_calpain_cat | 7.71e-08 | 15 | 53 | 4 | IPR001300 | |
| Domain | Peptidase_C2 | 7.71e-08 | 15 | 53 | 4 | PF00648 | |
| Domain | CALPAIN_CAT | 7.71e-08 | 15 | 53 | 4 | PS50203 | |
| Domain | THIOL_PROTEASE_CYS | 8.25e-07 | 26 | 53 | 4 | PS00139 | |
| Domain | THIOL_PROTEASE_ASN | 9.66e-07 | 27 | 53 | 4 | PS00640 | |
| Domain | THIOL_PROTEASE_HIS | 9.66e-07 | 27 | 53 | 4 | PS00639 | |
| Domain | Pept_cys_AS | 1.12e-06 | 28 | 53 | 4 | IPR000169 | |
| Domain | ROCK1/ROCK2 | 7.90e-06 | 2 | 53 | 2 | IPR020684 | |
| Domain | Ribosomal_L10e_CS | 7.90e-06 | 2 | 53 | 2 | IPR018255 | |
| Domain | Rho_Binding | 7.90e-06 | 2 | 53 | 2 | PF08912 | |
| Domain | Ribosomal_L10e | 7.90e-06 | 2 | 53 | 2 | IPR001197 | |
| Domain | Rho-bd_dom | 7.90e-06 | 2 | 53 | 2 | IPR015008 | |
| Domain | RIBOSOMAL_L10E | 7.90e-06 | 2 | 53 | 2 | PS01257 | |
| Domain | Channel_four-helix_dom | 2.04e-05 | 57 | 53 | 4 | IPR027359 | |
| Domain | - | 2.04e-05 | 57 | 53 | 4 | 1.20.120.350 | |
| Domain | Ribosomal_L10e/L16 | 2.37e-05 | 3 | 53 | 2 | IPR016180 | |
| Domain | - | 2.37e-05 | 3 | 53 | 2 | 3.90.1170.10 | |
| Domain | Ribosomal_L16 | 2.37e-05 | 3 | 53 | 2 | PF00252 | |
| Domain | FIBRINOGEN_C_1 | 1.01e-04 | 32 | 53 | 3 | PS00514 | |
| Domain | Fibrinogen_a/b/g_C_dom | 1.01e-04 | 32 | 53 | 3 | IPR002181 | |
| Domain | FIBRINOGEN_C_2 | 1.01e-04 | 32 | 53 | 3 | PS51406 | |
| Domain | Na_trans_cytopl | 1.18e-04 | 6 | 53 | 2 | PF11933 | |
| Domain | Na_trans_cytopl | 1.18e-04 | 6 | 53 | 2 | IPR024583 | |
| Domain | EF-hand_8 | 1.21e-04 | 34 | 53 | 3 | PF13833 | |
| Domain | IQ_motif_EF-hand-BS | 1.23e-04 | 90 | 53 | 4 | IPR000048 | |
| Domain | EF_Hand_1_Ca_BS | 1.36e-04 | 175 | 53 | 5 | IPR018247 | |
| Domain | IQ | 1.40e-04 | 93 | 53 | 4 | PS50096 | |
| Domain | EF-hand-dom_pair | 1.56e-04 | 287 | 53 | 6 | IPR011992 | |
| Domain | LAM_G_DOMAIN | 1.70e-04 | 38 | 53 | 3 | PS50025 | |
| Domain | Laminin_G_2 | 1.98e-04 | 40 | 53 | 3 | PF02210 | |
| Domain | HR1 | 2.19e-04 | 8 | 53 | 2 | PF02185 | |
| Domain | LamG | 2.63e-04 | 44 | 53 | 3 | SM00282 | |
| Domain | EF_HAND_1 | 2.77e-04 | 204 | 53 | 5 | PS00018 | |
| Domain | Ion_trans_dom | 3.06e-04 | 114 | 53 | 4 | IPR005821 | |
| Domain | Ion_trans | 3.06e-04 | 114 | 53 | 4 | PF00520 | |
| Domain | EGF | 4.48e-04 | 126 | 53 | 4 | PF00008 | |
| Domain | EF_HAND_2 | 4.90e-04 | 231 | 53 | 5 | PS50222 | |
| Domain | EF_hand_dom | 5.00e-04 | 232 | 53 | 5 | IPR002048 | |
| Domain | EGF | 5.30e-04 | 235 | 53 | 5 | SM00181 | |
| Domain | Laminin_G | 5.96e-04 | 58 | 53 | 3 | IPR001791 | |
| Domain | EGF-like_dom | 6.89e-04 | 249 | 53 | 5 | IPR000742 | |
| Domain | Neurexin-like | 7.03e-04 | 14 | 53 | 2 | IPR003585 | |
| Domain | 4.1m | 7.03e-04 | 14 | 53 | 2 | SM00294 | |
| Domain | - | 8.51e-04 | 261 | 53 | 5 | 1.10.238.10 | |
| Domain | EF-hand_1 | 9.06e-04 | 152 | 53 | 4 | PF00036 | |
| Domain | EFh | 1.05e-03 | 158 | 53 | 4 | SM00054 | |
| Domain | IQ | 1.08e-03 | 71 | 53 | 3 | PF00612 | |
| Domain | - | 1.17e-03 | 73 | 53 | 3 | 2.60.120.260 | |
| Domain | IQ | 1.57e-03 | 81 | 53 | 3 | SM00015 | |
| Domain | FA58C | 1.60e-03 | 21 | 53 | 2 | SM00231 | |
| Domain | FA58C_3 | 1.60e-03 | 21 | 53 | 2 | PS50022 | |
| Domain | FA58C_1 | 1.60e-03 | 21 | 53 | 2 | PS01285 | |
| Domain | FA58C_2 | 1.60e-03 | 21 | 53 | 2 | PS01286 | |
| Domain | F5_F8_type_C | 2.10e-03 | 24 | 53 | 2 | PF00754 | |
| Domain | FA58C | 2.10e-03 | 24 | 53 | 2 | IPR000421 | |
| Domain | Galactose-bd-like | 2.41e-03 | 94 | 53 | 3 | IPR008979 | |
| Domain | LIPASE_SER | 2.46e-03 | 26 | 53 | 2 | PS00120 | |
| Domain | - | 2.48e-03 | 95 | 53 | 3 | 2.60.120.200 | |
| Domain | Fibrinogen_C | 2.65e-03 | 27 | 53 | 2 | PF00147 | |
| Domain | FBG | 3.05e-03 | 29 | 53 | 2 | SM00186 | |
| Domain | Spectrin_repeat | 3.05e-03 | 29 | 53 | 2 | IPR002017 | |
| Domain | - | 3.27e-03 | 30 | 53 | 2 | 3.90.215.10 | |
| Domain | Fibrinogen_a/b/g_C_1 | 3.27e-03 | 30 | 53 | 2 | IPR014716 | |
| Domain | Spectrin/alpha-actinin | 3.71e-03 | 32 | 53 | 2 | IPR018159 | |
| Pathway | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | 2.22e-06 | 31 | 43 | 4 | M877 | |
| Pathway | REACTOME_PHASE_0_RAPID_DEPOLARISATION | 2.54e-06 | 32 | 43 | 4 | M27455 | |
| Pathway | WP_INTEGRINMEDIATED_CELL_ADHESION | 1.39e-05 | 102 | 43 | 5 | M39577 | |
| Pathway | WP_INTEGRINMEDIATED_CELL_ADHESION | 1.39e-05 | 102 | 43 | 5 | MM15830 | |
| Pathway | REACTOME_L1CAM_INTERACTIONS | 3.18e-05 | 121 | 43 | 5 | M872 | |
| Pathway | REACTOME_NERVOUS_SYSTEM_DEVELOPMENT | 4.78e-05 | 575 | 43 | 9 | M29853 | |
| Pathway | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | 6.39e-05 | 140 | 43 | 5 | M587 | |
| Pathway | KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_MAP_TO_LPA_GNA12_13_RHOA_SIGNALING_PATHWAY | 9.04e-05 | 5 | 43 | 2 | M49031 | |
| Pathway | REACTOME_RHO_GTPASES_ACTIVATE_ROCKS | 9.04e-05 | 5 | 43 | 2 | MM15221 | |
| Pathway | REACTOME_DEVELOPMENTAL_BIOLOGY | ROCK2 RPL10L TUT4 SCN1A CAPN1 SCN4A CNTNAP1 SCN5A SCN10A ROCK1 LIPN PCK1 RPL10 | 2.30e-04 | 1432 | 43 | 13 | M509 |
| Pathway | REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION | 2.78e-04 | 300 | 43 | 6 | M610 | |
| Pathway | KEGG_MEDICUS_REFERENCE_CXCR4_GNA12_13_RHO_SIGNALING_PATHWAY | 3.23e-04 | 9 | 43 | 2 | M47546 | |
| Pathway | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | 3.93e-04 | 114 | 43 | 4 | MM14571 | |
| Pathway | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | 4.91e-04 | 11 | 43 | 2 | MM15046 | |
| Pathway | KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAA_TO_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY | 4.91e-04 | 11 | 43 | 2 | M47721 | |
| Pathway | REACTOME_CARDIAC_CONDUCTION | 6.45e-04 | 130 | 43 | 4 | M27454 | |
| Pathway | KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNA12_13_RHO_SIGNALING_PATHWAY | 6.94e-04 | 13 | 43 | 2 | M47547 | |
| Pathway | KEGG_MEDICUS_REFERENCE_LPA_GNA12_13_RHOA_SIGNALING_PATHWAY | 6.94e-04 | 13 | 43 | 2 | M47731 | |
| Pathway | WP_ADHD_AND_AUTISM_ASD_PATHWAYS | 8.07e-04 | 367 | 43 | 6 | M48346 | |
| Pathway | REACTOME_RHOA_GTPASE_CYCLE | 8.98e-04 | 142 | 43 | 4 | MM15576 | |
| Pathway | PID_THROMBIN_PAR4_PATHWAY | 9.31e-04 | 15 | 43 | 2 | M138 | |
| Pathway | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | 9.31e-04 | 15 | 43 | 2 | MM15037 | |
| Pathway | WP_AIRWAY_SMOOTH_MUSCLE_CELL_CONTRACTION | 1.06e-03 | 16 | 43 | 2 | M40060 | |
| Pathway | REACTOME_RHOA_GTPASE_CYCLE | 1.07e-03 | 149 | 43 | 4 | M41805 | |
| Pathway | REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION | 1.08e-03 | 258 | 43 | 5 | MM14572 | |
| Pathway | REACTOME_RHOB_GTPASE_CYCLE | 1.20e-03 | 69 | 43 | 3 | MM15596 | |
| Pathway | REACTOME_RHOB_GTPASE_CYCLE | 1.26e-03 | 70 | 43 | 3 | M41806 | |
| Pathway | REACTOME_RHOC_GTPASE_CYCLE | 1.26e-03 | 70 | 43 | 3 | MM15597 | |
| Pathway | REACTOME_RHOC_GTPASE_CYCLE | 1.47e-03 | 74 | 43 | 3 | M41807 | |
| Pathway | REACTOME_RHO_GTPASES_ACTIVATE_ROCKS | 1.50e-03 | 19 | 43 | 2 | M27493 | |
| Pathway | REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS | 1.65e-03 | 77 | 43 | 3 | MM15044 | |
| Pathway | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | 1.67e-03 | 20 | 43 | 2 | M18415 | |
| Pathway | KEGG_MEDICUS_REFERENCE_MICROTUBULE_RHOA_SIGNALING_PATHWAY | 1.84e-03 | 21 | 43 | 2 | M47767 | |
| Pathway | REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS | 1.84e-03 | 80 | 43 | 3 | M800 | |
| Pathway | REACTOME_RHOBTB1_GTPASE_CYCLE | 2.21e-03 | 23 | 43 | 2 | M41817 | |
| Pathway | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | 2.40e-03 | 24 | 43 | 2 | M2243 | |
| Pathway | REACTOME_RHOBTB1_GTPASE_CYCLE | 2.61e-03 | 25 | 43 | 2 | MM15608 | |
| Pathway | REACTOME_MUSCLE_CONTRACTION | 3.32e-03 | 203 | 43 | 4 | M5485 | |
| Pathway | REACTOME_EPHA_MEDIATED_GROWTH_CONE_COLLAPSE | 3.50e-03 | 29 | 43 | 2 | M27309 | |
| Pubmed | 7.55e-10 | 9 | 56 | 4 | 16382098 | ||
| Pubmed | 2.20e-07 | 8 | 56 | 3 | 9412493 | ||
| Pubmed | 3.30e-07 | 9 | 56 | 3 | 15746173 | ||
| Pubmed | 1.12e-06 | 13 | 56 | 3 | 15123669 | ||
| Pubmed | A common genetic variant within SCN10A modulates cardiac SCN5A expression. | 2.55e-06 | 2 | 56 | 2 | 24642470 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 35523828 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 29115372 | ||
| Pubmed | Investigation of the Rho-kinase Gene Polymorphism in Primary Open-angle Glaucoma. | 2.55e-06 | 2 | 56 | 2 | 24617500 | |
| Pubmed | [Ouabain induces Rho-dependent rock activation and membrane blebbing incultured endothelial cells]. | 2.55e-06 | 2 | 56 | 2 | 25916120 | |
| Pubmed | Sulfide induces apoptosis and Rho kinase-dependent cell blebbing in Jurkat cells. | 2.55e-06 | 2 | 56 | 2 | 23479079 | |
| Pubmed | Evidence for Rho-kinase activation in patients with pulmonary arterial hypertension. | 2.55e-06 | 2 | 56 | 2 | 19590140 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 24429217 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 12778124 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 18495812 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 26468018 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 28035042 | ||
| Pubmed | ROCK1 and ROCK2 regulate epithelial polarisation and geometric cell shape. | 2.55e-06 | 2 | 56 | 2 | 22462535 | |
| Pubmed | Distinct Roles For ROCK1 and ROCK2 in the Regulation of Oxldl-Mediated Endothelial Dysfunction. | 2.55e-06 | 2 | 56 | 2 | 30165352 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 32877952 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 30196430 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 29800294 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 18668558 | ||
| Pubmed | Role of Rho-kinase in regulation of insulin action and glucose homeostasis. | 2.55e-06 | 2 | 56 | 2 | 16098829 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 28709411 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 32234882 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 15096457 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 21471517 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 15047701 | ||
| Pubmed | Rho kinase inhibitors block melanoma cell migration and inhibit metastasis. | 2.55e-06 | 2 | 56 | 2 | 25840982 | |
| Pubmed | ROCK1 & 2 perform overlapping and unique roles in angiogenesis and angiosarcoma tumor progression. | 2.55e-06 | 2 | 56 | 2 | 22934846 | |
| Pubmed | ROCK-I and ROCK-II cooperatively regulate closure of eyelid and ventral body wall in mouse embryo. | 2.55e-06 | 2 | 56 | 2 | 16098146 | |
| Pubmed | Functional role of Rho-kinase in ameloblast differentiation. | 2.55e-06 | 2 | 56 | 2 | 21792909 | |
| Pubmed | Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity. | 2.55e-06 | 2 | 56 | 2 | 20803696 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 17157313 | ||
| Pubmed | Role of Rho Kinase and Fasudil on Synaptic Plasticity in Multiple Sclerosis. | 2.55e-06 | 2 | 56 | 2 | 26481340 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 18331468 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 29211497 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 30369081 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 29987023 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 8772201 | ||
| Pubmed | ROCK isoform regulation of myosin phosphatase and contractility in vascular smooth muscle cells. | 2.55e-06 | 2 | 56 | 2 | 19131646 | |
| Pubmed | Fasudil or genetic depletion of ROCK1 or ROCK2 induces anxiety-like behaviors. | 2.55e-06 | 2 | 56 | 2 | 31302146 | |
| Pubmed | Role of rho-kinase gene polymorphisms and protein expressions in colorectal cancer development. | 2.55e-06 | 2 | 56 | 2 | 23328676 | |
| Pubmed | The expression and prognostic value of ROCK I and ROCK II and their role in human breast cancer. | 2.55e-06 | 2 | 56 | 2 | 18695890 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 20169147 | ||
| Pubmed | Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif. | 2.55e-06 | 2 | 56 | 2 | 30944319 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 31292628 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 24170433 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 12508221 | ||
| Pubmed | ROCK2 Regulates Monocyte Migration and Cell to Cell Adhesion in Vascular Endothelial Cells. | 2.55e-06 | 2 | 56 | 2 | 30884801 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 18695640 | ||
| Pubmed | Rho-associated kinases play a role in endocardial cell differentiation and migration. | 2.55e-06 | 2 | 56 | 2 | 15464581 | |
| Pubmed | Investigation of the esophageal Rho-kinase expression in patients with Barrett's esophagus. | 2.55e-06 | 2 | 56 | 2 | 23789633 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 28225294 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 15044207 | ||
| Pubmed | Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine. | 2.55e-06 | 2 | 56 | 2 | 16054936 | |
| Pubmed | ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury. | 2.55e-06 | 2 | 56 | 2 | 18414683 | |
| Pubmed | ROCK2 inhibition enhances the thermogenic program in white and brown fat tissue in mice. | 2.55e-06 | 2 | 56 | 2 | 31914704 | |
| Pubmed | Differential regulation of adhesion complex turnover by ROCK1 and ROCK2. | 2.55e-06 | 2 | 56 | 2 | 22348083 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 33712547 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 30771534 | ||
| Pubmed | Rho-associated kinase is a therapeutic target in neuroblastoma. | 2.55e-06 | 2 | 56 | 2 | 28739902 | |
| Pubmed | Matrix rigidity differentially regulates invadopodia activity through ROCK1 and ROCK2. | 2.55e-06 | 2 | 56 | 2 | 26826790 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 24562870 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 25934709 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 29246448 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 11834499 | ||
| Pubmed | ROCK insufficiency attenuates ozone-induced airway hyperresponsiveness in mice. | 2.55e-06 | 2 | 56 | 2 | 26276827 | |
| Pubmed | Fibroblast deletion of ROCK2 attenuates cardiac hypertrophy, fibrosis, and diastolic dysfunction. | 2.55e-06 | 2 | 56 | 2 | 28679962 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 27791202 | ||
| Pubmed | ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. | 2.55e-06 | 2 | 56 | 2 | 38199985 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 17167780 | ||
| Pubmed | ROCK in CNS: Different Roles of Isoforms and Therapeutic Target for Neurodegenerative Disorders. | 2.55e-06 | 2 | 56 | 2 | 27033194 | |
| Pubmed | Association of Rho-kinase Gene Polymorphisms with Respiratory Distress Syndrome in Preterm Neonates. | 2.55e-06 | 2 | 56 | 2 | 27269648 | |
| Pubmed | Overexpression of ROCK1 and ROCK2 inhibits human laryngeal squamous cell carcinoma. | 2.55e-06 | 2 | 56 | 2 | 25755711 | |
| Pubmed | Hyperoxia increases the elastic modulus of alveolar epithelial cells through Rho kinase. | 2.55e-06 | 2 | 56 | 2 | 24289040 | |
| Pubmed | Targeting ROCK1/2 blocks cell division and induces mitotic catastrophe in hepatocellular carcinoma. | 2.55e-06 | 2 | 56 | 2 | 33278350 | |
| Pubmed | Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment. | 2.55e-06 | 2 | 56 | 2 | 23392171 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 23250919 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 28923399 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 17347801 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 24168723 | ||
| Pubmed | Distinct distribution and localization of Rho-kinase in mouse epithelial, muscle and neural tissues. | 2.55e-06 | 2 | 56 | 2 | 22986902 | |
| Pubmed | Dissecting the roles of ROCK isoforms in stress-induced cell detachment. | 2.55e-06 | 2 | 56 | 2 | 23598717 | |
| Pubmed | Activation of Rho kinase isoforms in lung endothelial cells during inflammation. | 2.55e-06 | 2 | 56 | 2 | 19201893 | |
| Pubmed | ROCK regulates the intermittent mode of interstitial T cell migration in inflamed lungs. | 2.55e-06 | 2 | 56 | 2 | 29044117 | |
| Pubmed | Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation. | 2.55e-06 | 2 | 56 | 2 | 19997641 | |
| Pubmed | Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome. | 2.55e-06 | 2 | 56 | 2 | 24998131 | |
| Pubmed | Role of Rho kinase isoforms in murine allergic airway responses. | 2.55e-06 | 2 | 56 | 2 | 21565918 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 27203208 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 22355071 | ||
| Pubmed | The ROCK isoforms differentially regulate the morphological characteristics of carcinoma cells. | 2.55e-06 | 2 | 56 | 2 | 28650698 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 22942252 | ||
| Pubmed | Genetic and pharmacological inhibition of Rho-associated kinase II enhances adipogenesis. | 2.55e-06 | 2 | 56 | 2 | 17681946 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 24360055 | ||
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 23946538 | ||
| Pubmed | The Rho kinase pathway regulates mouse adult neural precursor cell migration. | 2.55e-06 | 2 | 56 | 2 | 21732490 | |
| Pubmed | Rho kinases play an obligatory role in vertebrate embryonic organogenesis. | 2.55e-06 | 2 | 56 | 2 | 11532918 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 27251065 | ||
| Pubmed | Role of ROCK2 in CD4+ cells in allergic airways responses in mice. | 2.55e-06 | 2 | 56 | 2 | 27886408 | |
| Interaction | CACNA1A interactions | 6.58e-07 | 123 | 51 | 6 | int:CACNA1A | |
| Interaction | SCN1A interactions | 8.24e-07 | 29 | 51 | 4 | int:SCN1A | |
| Interaction | SCN10A interactions | 2.48e-06 | 11 | 51 | 3 | int:SCN10A | |
| Interaction | SCN11A interactions | 6.80e-06 | 15 | 51 | 3 | int:SCN11A | |
| Interaction | CAPN3 interactions | 1.05e-05 | 54 | 51 | 4 | int:CAPN3 | |
| Interaction | DNAJC3 interactions | 2.20e-05 | 226 | 51 | 6 | int:DNAJC3 | |
| Interaction | CACNA1D interactions | 2.98e-05 | 24 | 51 | 3 | int:CACNA1D | |
| Interaction | C1orf54 interactions | 6.35e-05 | 167 | 51 | 5 | int:C1orf54 | |
| Interaction | CCL3 interactions | 8.59e-05 | 178 | 51 | 5 | int:CCL3 | |
| GeneFamily | Sodium voltage-gated channel alpha subunits | 1.86e-09 | 9 | 37 | 4 | 1203 | |
| GeneFamily | C2 domain containing|Calpains | 1.99e-08 | 15 | 37 | 4 | 975 | |
| GeneFamily | EF-hand domain containing | 7.92e-05 | 219 | 37 | 5 | 863 | |
| GeneFamily | L ribosomal proteins | 4.88e-03 | 51 | 37 | 2 | 729 | |
| ToppCell | BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k) | 4.09e-06 | 190 | 56 | 5 | 91ba66d4b56c59523485b17738e93f14bb00afa4 | |
| ToppCell | human_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells) | 4.30e-06 | 192 | 56 | 5 | 916fbec1c7ab7969bda711886ac88e877e30c280 | |
| ToppCell | human_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells) | 4.41e-06 | 193 | 56 | 5 | e6a688bc834f845ff64dae1be64f073eec5091a1 | |
| Drug | P6Chol | 1.05e-06 | 9 | 54 | 3 | CID000126085 | |
| Drug | Hexylcaine | 5.52e-06 | 2 | 54 | 2 | DB00473 | |
| Drug | Phenytoin | 5.52e-06 | 2 | 54 | 2 | DB00252 | |
| Drug | Flecainide | 5.52e-06 | 2 | 54 | 2 | DB01195 | |
| Drug | Rockout | 5.52e-06 | 2 | 54 | 2 | CID000644354 | |
| Drug | 3,3-dimethylacryloyl chloride | 5.52e-06 | 2 | 54 | 2 | CID000102394 | |
| Drug | Zonisamide | 8.38e-06 | 17 | 54 | 3 | DB00909 | |
| Drug | Dibucaine | 1.65e-05 | 3 | 54 | 2 | DB00527 | |
| Drug | dibucaine | 2.06e-05 | 68 | 54 | 4 | CID000003025 | |
| Drug | Lidocaine | 3.30e-05 | 4 | 54 | 2 | DB00281 | |
| Drug | diguanosine pentaphosphate | 3.30e-05 | 4 | 54 | 2 | CID004577574 | |
| Drug | AC1L1MOZ | 3.54e-05 | 27 | 54 | 3 | CID000031958 | |
| Drug | tocainide | 4.89e-05 | 30 | 54 | 3 | CID000038945 | |
| Drug | tetrahydrooxazine | 5.50e-05 | 5 | 54 | 2 | CID000449101 | |
| Drug | AC1L9XAW | 6.54e-05 | 33 | 54 | 3 | CID000477669 | |
| Drug | AC1O7GGT | 6.54e-05 | 33 | 54 | 3 | CID000004460 | |
| Drug | Hypertensin II | 6.62e-05 | 429 | 54 | 7 | CID000025476 | |
| Drug | AC1L1DW2 | 7.88e-05 | 186 | 54 | 5 | CID000002532 | |
| Drug | brazilein | 8.23e-05 | 6 | 54 | 2 | CID006453902 | |
| Drug | APETx1, Anthopleura elegantissima | 8.23e-05 | 6 | 54 | 2 | ctd:C475726 | |
| Drug | levormeloxifene | 8.23e-05 | 6 | 54 | 2 | ctd:C108255 | |
| Drug | AC1L1CTF | 8.23e-05 | 6 | 54 | 2 | CID000002056 | |
| Drug | chloromethyl | 9.85e-05 | 195 | 54 | 5 | CID000007835 | |
| Drug | Cyanocobalamin [68-19-9]; Up 200; 3uM; PC3; HT_HG-U133A | 1.03e-04 | 197 | 54 | 5 | 4572_UP | |
| Drug | Amoxapine [14028-44-5]; Up 200; 12.8uM; MCF7; HT_HG-U133A | 1.03e-04 | 197 | 54 | 5 | 1513_UP | |
| Drug | Brompheniramine maleate [980-71-2]; Down 200; 9.2uM; MCF7; HT_HG-U133A | 1.06e-04 | 198 | 54 | 5 | 4131_DN | |
| Drug | Clebopride maleate [84370-95-6]; Down 200; 8.2uM; PC3; HT_HG-U133A | 1.08e-04 | 199 | 54 | 5 | 6311_DN | |
| Drug | 6-BME | 1.15e-04 | 7 | 54 | 2 | CID005748218 | |
| Drug | artocarpin lectin | 1.15e-04 | 7 | 54 | 2 | CID005358260 | |
| Drug | AC1L2VEC | 1.15e-04 | 7 | 54 | 2 | CID000129320 | |
| Drug | GGTI-297 | 1.53e-04 | 8 | 54 | 2 | CID009956145 | |
| Drug | heptenoic acid | 1.53e-04 | 8 | 54 | 2 | CID000029373 | |
| Drug | 3-octene | 1.53e-04 | 8 | 54 | 2 | CID000032935 | |
| Drug | Cocaine | 1.53e-04 | 8 | 54 | 2 | DB00907 | |
| Drug | N-palmitoyl-serine | 1.53e-04 | 8 | 54 | 2 | CID000085997 | |
| Drug | oxethazaine | 1.53e-04 | 8 | 54 | 2 | CID000004621 | |
| Drug | SC-46275 | 1.53e-04 | 8 | 54 | 2 | CID005311427 | |
| Drug | Y-26763 | 1.53e-04 | 8 | 54 | 2 | CID000121878 | |
| Drug | SC-560 | 1.56e-04 | 44 | 54 | 3 | CID004306515 | |
| Drug | pilsicainide | 1.78e-04 | 46 | 54 | 3 | CID000004820 | |
| Drug | cyclaine | 1.97e-04 | 9 | 54 | 2 | CID000010770 | |
| Drug | SDMP | 1.97e-04 | 9 | 54 | 2 | CID000094924 | |
| Drug | 2-pentene | 1.97e-04 | 9 | 54 | 2 | CID000012585 | |
| Drug | Mexiletine | 1.97e-04 | 9 | 54 | 2 | ctd:D008801 | |
| Disease | generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology) | 2.25e-09 | 10 | 55 | 4 | DOID:0111294 (implicated_via_orthology) | |
| Disease | Dravet syndrome (implicated_via_orthology) | 2.25e-09 | 10 | 55 | 4 | DOID:0080422 (implicated_via_orthology) | |
| Disease | generalized epilepsy with febrile seizures plus (implicated_via_orthology) | 5.29e-09 | 12 | 55 | 4 | DOID:0060170 (implicated_via_orthology) | |
| Disease | Heart Septal Defects | 1.02e-05 | 3 | 55 | 2 | C0018816 | |
| Disease | T-cell acute lymphoblastic leukemia (implicated_via_orthology) | 1.02e-05 | 3 | 55 | 2 | DOID:5603 (implicated_via_orthology) | |
| Disease | autistic disorder (implicated_via_orthology) | 2.04e-05 | 4 | 55 | 2 | DOID:12849 (implicated_via_orthology) | |
| Disease | Brugada ECG Pattern | 2.04e-05 | 4 | 55 | 2 | C1721096 | |
| Disease | hereditary spastic paraplegia 76 (implicated_via_orthology) | 3.40e-05 | 5 | 55 | 2 | DOID:0110821 (implicated_via_orthology) | |
| Disease | Duchenne muscular dystrophy (implicated_via_orthology) | 4.19e-05 | 36 | 55 | 3 | DOID:11723 (implicated_via_orthology) | |
| Disease | spondyloepiphyseal dysplasia congenita (implicated_via_orthology) | 5.09e-05 | 6 | 55 | 2 | DOID:14789 (implicated_via_orthology) | |
| Disease | syndromic X-linked intellectual disability Najm type (implicated_via_orthology) | 7.12e-05 | 7 | 55 | 2 | DOID:0060807 (implicated_via_orthology) | |
| Disease | electrocardiography, PR interval | 7.12e-05 | 7 | 55 | 2 | EFO_0004327, EFO_0004462 | |
| Disease | hereditary spastic paraplegia (implicated_via_orthology) | 7.17e-05 | 43 | 55 | 3 | DOID:2476 (implicated_via_orthology) | |
| Disease | autosomal recessive intellectual developmental disorder (implicated_via_orthology) | 9.48e-05 | 8 | 55 | 2 | DOID:0060308 (implicated_via_orthology) | |
| Disease | Ventricular Septal Defects | 9.48e-05 | 8 | 55 | 2 | C0018818 | |
| Disease | supraventricular ectopy | 1.22e-04 | 9 | 55 | 2 | EFO_0009277 | |
| Disease | Tendinopathy | 1.22e-04 | 9 | 55 | 2 | EFO_1001434 | |
| Disease | epilepsy (implicated_via_orthology) | 2.46e-04 | 163 | 55 | 4 | DOID:1826 (implicated_via_orthology) | |
| Disease | Brugada Syndrome 1 | 2.63e-04 | 13 | 55 | 2 | C4551804 | |
| Disease | T wave morphology measurement | 3.06e-04 | 14 | 55 | 2 | EFO_0008398 | |
| Disease | P wave duration | 3.53e-04 | 15 | 55 | 2 | EFO_0005094 | |
| Disease | Romano-Ward Syndrome | 4.03e-04 | 16 | 55 | 2 | C0035828 | |
| Disease | Brugada syndrome | 5.72e-04 | 19 | 55 | 2 | MONDO_0015263 | |
| Disease | urinary microalbumin measurement | 6.34e-04 | 20 | 55 | 2 | EFO_0010967 | |
| Disease | Brugada Syndrome (disorder) | 9.17e-04 | 24 | 55 | 2 | C1142166 | |
| Disease | cardiovascular age measurement | 1.34e-03 | 29 | 55 | 2 | EFO_0803380 | |
| Disease | heart function measurement | 1.84e-03 | 34 | 55 | 2 | EFO_0004311 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| WDVFAFSFKTEEKDG | 196 | P78357 | |
| LFNFSGEDMEWDAEL | 276 | A0A1B0GVH6 | |
| MWEAFQFEKSQASEF | 911 | Q96M86 | |
| HKTEDGEFWMSYQDF | 351 | Q9UMQ6 | |
| DGEFWMSFRDFMREF | 331 | P07384 | |
| DNDGEFWMTLQDFKT | 311 | A8MX76 | |
| WMSEEDFEKAFNARF | 116 | P35558 | |
| QEFDVFSVMDWKDGV | 11 | Q96JM7 | |
| GAGDFSEFFEWQKKM | 326 | D6REC4 | |
| EKFWAFSFDEMAKYD | 136 | Q5VXI9 | |
| DDDDDVSFAKWMSSF | 6 | A1A4G5 | |
| DLWLNEGFAKFMEFV | 371 | Q9NZ08 | |
| LFDHSMEGFKNWEFM | 541 | Q92824 | |
| WFNISGGDKDMDFDI | 1381 | Q9NYQ8 | |
| WMFAVEQDGFKNGFS | 496 | P14543 | |
| MESDSFEDFWKGEDL | 6 | P25025 | |
| KEKFMDEDLSFFSGW | 156 | Q5VWM3 | |
| SQEDLTFLWDMFGEK | 31 | Q5T2T1 | |
| KDMEYFFGENWEEQV | 111 | P30519 | |
| FDSMWPELANTFEDF | 1486 | Q7Z3U7 | |
| MELAAGSFSEEQFWE | 1 | Q9UKL6 | |
| MQFSTWDNDNDKFEG | 336 | P02679 | |
| DSEDMWGDEDFTFGA | 276 | Q8TES7 | |
| FHGTDFDTVFWKCDM | 111 | Q86V35 | |
| WFEDCEMDGDKNSIF | 936 | Q9UHN6 | |
| TDIGFWFSQEDFMLK | 41 | P10911 | |
| CNKDVGAFFEEGMWL | 1001 | Q9UHC6 | |
| ALDDGEFWMAFKDFK | 311 | O14815 | |
| WGFTKFNADEFEDMV | 171 | Q96L21 | |
| EAEMFGWSFVFEDFV | 86 | Q8NBJ7 | |
| DFEMFYETWEKFDPD | 1616 | P35499 | |
| FSESMQEFQEWFLGA | 2411 | Q8NF91 | |
| WGFTKFNADEFEDMV | 171 | P27635 | |
| MANFAYVKWEAGIDD | 1676 | Q14524 | |
| YVKWEAGIDDMFNFQ | 1681 | Q14524 | |
| FDMFYEIWEKFDPEA | 1791 | Q14524 | |
| WDVFFGFEENKCSMS | 26 | Q75T13 | |
| VWEKFDPDATQFMEF | 1811 | P35498 | |
| FVFYEDWGENMVSKS | 206 | P13798 | |
| DWDSFFRDAKDMNET | 126 | Q02040 | |
| LWLGQNEFDFMTDFV | 246 | Q99967 | |
| EFFRKMELFASWSDE | 236 | Q96M20 | |
| KWEDGSVISENMFEF | 171 | Q9P126 | |
| FGADYDWFFIMQDDT | 171 | Q9P2E5 | |
| FMDVAIEFSQEEWKS | 26 | Q8N9Z0 | |
| FWMELEDDGKVDFIF | 11 | Q96T68 | |
| DAWMSKQFQAFGDLF | 316 | Q7Z392 | |
| FDMFYETWEKFDPEA | 1741 | Q9Y5Y9 | |
| QIEDMFEQGKWDVFS | 176 | O75558 | |
| VKFWDFAGMDASFKA | 206 | Q9NW82 | |
| SIDDWVFMCFFVGND | 331 | Q9H0D6 | |
| FEMIKRSDSAFFWEE | 126 | O75116 | |
| QDELVFAWEDVKAMF | 221 | Q2VWA4 | |
| SDSAFFWEERDIMAF | 116 | Q13464 | |
| AEEEKAMDFSVLWDF | 296 | Q8TDI7 | |
| EASEFMAEESNEKFW | 51 | Q9NYU1 | |
| MVDGWNAFFFDKTEE | 1156 | Q5TAX3 | |
| SFTEEEFMKALEWGN | 376 | Q8N6V9 |