Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentcell-cell junction

PRKCG LIMS1 PLCG1 KCNA5 OCLN AJM1 CDH18

9.76e-05591397GO:0005911
GeneOntologyCellularComponentanchoring junction

PRKCG LIMS1 PLCG1 KCNA5 OCLN G3BP1 AJM1 CDH18

3.71e-04976398GO:0070161
MousePhenoabnormal tail morphology

GLMN GNA11 FAT4 THBS2 G3BP1 PLXNB2 COL1A2

3.51e-05403337MP:0002111
DomainTSP3

THBS1 THBS2

4.02e-055382PS51234
DomainTSP_CTER

THBS1 THBS2

4.02e-055382PS51236
Domain-

THBS1 THBS2

4.02e-0553824.10.1080.10
DomainThrombospondin_C

THBS1 THBS2

4.02e-055382IPR008859
DomainTSP_C

THBS1 THBS2

4.02e-055382PF05735
DomainThrombospondin_3_rpt

THBS1 THBS2

4.02e-055382IPR017897
DomainTSP_3

THBS1 THBS2

4.02e-055382PF02412
DomainThrombospondin_3-like_rpt

THBS1 THBS2

4.02e-055382IPR003367
DomainTSP_type-3_rpt

THBS1 THBS2

4.02e-055382IPR028974
DomainConA-like_dom

FAT4 THBS1 THBS2 HNRNPUL2 NBEAL2

7.76e-05219385IPR013320
DomainLaminin_G

FAT4 THBS1 THBS2

2.22e-0458383IPR001791
DomainEGF_CA

FAT4 THBS1 THBS2

7.08e-0486383PF07645
Domain-

FAT4 THBS1 THBS2

9.45e-04953832.60.120.200
DomainTSPN

THBS1 THBS2

9.93e-0423382SM00210
DomainEGF_3

FAT4 THBS1 THBS2 VWDE

1.29e-03235384PS50026
DomainEGF

FAT4 THBS1 THBS2 VWDE

1.29e-03235384SM00181
DomainVWC

THBS1 THBS2

1.47e-0328382PF00093
DomainEGF-like_dom

FAT4 THBS1 THBS2 VWDE

1.59e-03249384IPR000742
DomainEGF_1

FAT4 THBS1 THBS2 VWDE

1.74e-03255384PS00022
DomainEGF-like_CS

FAT4 THBS1 THBS2 VWDE

1.89e-03261384IPR013032
DomainEGF_CA

FAT4 THBS1 THBS2

1.94e-03122383SM00179
DomainEGF_2

FAT4 THBS1 THBS2 VWDE

2.00e-03265384PS01186
DomainEGF-like_Ca-bd_dom

FAT4 THBS1 THBS2

2.03e-03124383IPR001881
DomainVWFC_1

THBS1 THBS2

2.43e-0336382PS01208
DomainVWC

THBS1 THBS2

2.71e-0338382SM00214
DomainVWFC_2

THBS1 THBS2

2.71e-0338382PS50184
DomainVWF_dom

THBS1 THBS2

3.30e-0342382IPR001007
DomainEF_Hand_1_Ca_BS

PRKCSH PLCG1 SPATA21

5.36e-03175383IPR018247
DomainTSP_1

THBS1 THBS2

7.28e-0363382PF00090
DomainTSP1

THBS1 THBS2

7.73e-0365382SM00209
DomainTSP1_rpt

THBS1 THBS2

7.73e-0365382IPR000884
DomainTSP1

THBS1 THBS2

7.73e-0365382PS50092
DomainEF_HAND_1

PRKCSH PLCG1 SPATA21

8.18e-03204383PS00018
DomainEF_HAND_2

PRKCSH PLCG1 SPATA21

1.15e-02231383PS50222
DomainEF_hand_dom

PRKCSH PLCG1 SPATA21

1.16e-02232383IPR002048
PathwayWP_MIRNA_TARGETS_IN_ECM_AND_MEMBRANE_RECEPTORS

THBS1 THBS2 COL1A2

1.12e-0443313M39565
PathwayKEGG_MEDICUS_REFERENCE_TGFA_EGFR_PLCG_PKC_SIGNALING_PATHWAY

PRKCG PLCG1

1.30e-048312M47479
PathwayKEGG_VIBRIO_CHOLERAE_INFECTION

PRKCG PLCG1 SLC12A2

2.21e-0454313M17906
PathwayREACTOME_FREE_FATTY_ACIDS_REGULATE_INSULIN_SECRETION

ACSL3 GNA11

2.54e-0411312M27317
PathwayREACTOME_FREE_FATTY_ACIDS_REGULATE_INSULIN_SECRETION

ACSL3 GNA11

2.54e-0411312MM15035
PathwayKEGG_MEDICUS_REFERENCE_KISS1_KISS1R_PLCB_PKC_SIGNALING_PATHWAY

PRKCG GNA11

2.54e-0411312M47637
PathwayREACTOME_SIGNALING_BY_PDGF

THBS1 THBS2 PLCG1

2.60e-0457313MM14713
PathwayREACTOME_SIGNALING_BY_PDGF

THBS1 THBS2 PLCG1

2.74e-0458313M2049
PathwayKEGG_MEDICUS_REFERENCE_TRH_TRHR_PLCB_PKC_SIGNALING_PATHWAY

PRKCG GNA11

3.05e-0412312M47649
PathwayPID_ENDOTHELIN_PATHWAY

PRKCG GNA11 COL1A2

3.50e-0463313M8
PathwayPID_INTEGRIN1_PATHWAY

THBS1 THBS2 COL1A2

4.01e-0466313M18
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PLCG_ERK_SIGNALING_PATHWAY

PRKCG PLCG1

4.19e-0414312M47383
PathwayKEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PLCG_ERK_SIGNALING_PATHWAY

PRKCG PLCG1

4.19e-0414312M47384
PathwayWP_GPR40_PATHWAY

GNA11 PLCG1

4.83e-0415312M39526
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_ERK_SIGNALING_PATHWAY

PRKCG PLCG1

4.83e-0415312M47382
PathwayKEGG_MEDICUS_REFERENCE_CXCL12_CXCR4_PKC_ERK_SIGNALING_PATHAWAY

PRKCG PLCG1

7.82e-0419312M47596
PathwayKEGG_ECM_RECEPTOR_INTERACTION

THBS1 THBS2 COL1A2

8.13e-0484313M7098
PathwayWP_FOCAL_ADHESION

PRKCG THBS1 THBS2 COL1A2

8.99e-04199314M39402
PathwayKEGG_FOCAL_ADHESION

PRKCG THBS1 THBS2 COL1A2

8.99e-04199314M7253
PathwayKEGG_MEDICUS_REFERENCE_GNRH_GNRHR_PLCB_PKC_SIGNALING_PATHWAY

PRKCG GNA11

9.58e-0421312M47638
PathwayWP_PKCGAMMA_CALCIUM_SIGNALING_IN_ATAXIA

PRKCG GNA11

1.05e-0322312M39795
PathwayWP_HIPPO_SIGNALING_REGULATION

PRKCG GNA11 CDH18

1.27e-0398313M39830
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

PRKCG THBS1 THBS2 PRKCSH PLCG1 COL1A2

1.25e-0721039616537572
Pubmed

Mapping Extracellular Protein-Protein Interactions Using Extracellular Proximity Labeling (ePL).

ACSL3 GNA11 THBS1 THBS2 G3BP1 COL1A2

3.24e-0724739639238192
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

GNA11 PRKCSH PIGG SOCS6 SLC12A2 PLXNB2 HNRNPUL2 VPS13C

1.12e-0671939835337019
Pubmed

Induced thrombospondin expression in the mouse pancreas during pancreatic injury.

THBS1 THBS2

1.23e-06239216181801
Pubmed

Expression of thrombospondin-1 in ischemia-induced retinal neovascularization.

THBS1 THBS2

1.23e-06239210027393
Pubmed

Immunochemical analysis of the structure of the signature domains of thrombospondin-1 and thrombospondin-2 in low calcium concentrations.

THBS1 THBS2

1.23e-06239217620335
Pubmed

Human cytomegalovirus infection modulates thrombospondins 1 and 2 in primary fetal astrocytes.

THBS1 THBS2

1.23e-06239223660684
Pubmed

Increased excitatory connectivity and epileptiform activity in thrombospondin1/2 knockout mice following cortical trauma.

THBS1 THBS2

1.23e-06239239122122
Pubmed

Compound deletion of thrombospondin-1 and -2 results in a skeletal phenotype not predicted by the single gene knockouts.

THBS1 THBS2

1.23e-06239234425286
Pubmed

Thrombospondin-1 (TSP1)-null and TSP2-null mice exhibit lower intraocular pressures.

THBS1 THBS2

1.23e-06239222930728
Pubmed

Modulation of thrombospondin expression during differentiation of embryonal carcinoma cells.

THBS1 THBS2

1.23e-0623928126073
Pubmed

Contribution of Thrombospondin-1 and -2 to Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome.

THBS1 THBS2

1.23e-06239233981184
Pubmed

Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke.

THBS1 THBS2

1.23e-06239218594557
Pubmed

Roles of thrombospondin-1 and -2 in regulating corneal and iris angiogenesis.

THBS1 THBS2

1.23e-06239215037577
Pubmed

THBS1 and THBS2 Enhance the In Vitro Proliferation, Adhesion, Migration and Invasion of Intrahepatic Cholangiocarcinoma Cells.

THBS1 THBS2

1.23e-06239238339060
Pubmed

Circulating Levels of Thrombospondin-1 and Thrombospondin-2 in Patients with Temporal Lobe Epilepsy Before and After Surgery.

THBS1 THBS2

1.23e-06239233372257
Pubmed

An association study of thrombospondin 1 and 2 SNPs with coronary artery disease and myocardial infarction among South Indians.

THBS1 THBS2

1.23e-06239221762961
Pubmed

TSP1 and TSP2 Have Unique and Overlapping Roles in Protecting against Noise-Induced Auditory Synaptopathy.

THBS1 THBS2

1.23e-06239230928339
Pubmed

Restricted localization of thrombospondin-2 protein during mouse embryogenesis: a comparison to thrombospondin-1.

THBS1 THBS2

1.23e-0623929694593
Pubmed

The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice.

THBS1 THBS2

1.23e-06239212213711
Pubmed

Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization.

THBS1 THBS2

1.23e-06239217143334
Pubmed

Circulating Levels of Thrombospondin-1 and Thrombospondin-2 in Patients with Common Brain Tumors.

THBS1 THBS2

1.23e-06239233759165
Pubmed

Thrombospondin expression in aldosterone-producing adenomas.

THBS1 THBS2

1.23e-06239212358136
Pubmed

A second, expressed thrombospondin gene (Thbs2) exists in the mouse genome.

THBS1 THBS2

1.23e-0623921712771
Pubmed

Reduced expression of thrombospondins and craniofacial dysmorphism in mice overexpressing Fra1.

THBS1 THBS2

3.67e-06339216598380
Pubmed

Increased sensitivity to kindling in mice lacking TSP1.

THBS1 THBS2

3.67e-06339226241338
Pubmed

Expression and function of thrombospondin-1 in myelinating glial cells of the central nervous system.

THBS1 THBS2

3.67e-0633929373030
Pubmed

Differential Expression Pattern of THBS1 and THBS2 in Lung Cancer: Clinical Outcome and a Systematic-Analysis of Microarray Databases.

THBS1 THBS2

3.67e-06339227513329
Pubmed

Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury.

THBS1 THBS2

3.67e-06339218787106
Pubmed

Regulation of VEGF-A, VEGFR-I, thrombospondin-1, -2, and -3 expression in a human pituitary cell line (HP75) by TGFbeta1, bFGF, and EGF.

THBS1 THBS2

3.67e-06339215347840
Pubmed

Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells.

THBS1 THBS2

3.67e-06339218032585
Pubmed

Protein kinase C{gamma} mediates regulation of proliferation by the serotonin 5-hydroxytryptamine receptor 2B.

PRKCG PLCG1

3.67e-06339219531484
Pubmed

Association between single nucleotide polymorphisms in thrombospondins genes and coronary artery disease: A meta-analysis.

THBS1 THBS2

3.67e-06339225976449
Pubmed

Elevated THBS2, COL1A2, and SPP1 Expression Levels as Predictors of Gastric Cancer Prognosis.

THBS2 COL1A2

3.67e-06339227997896
Pubmed

The Pathological Significance and Prognostic Roles of Thrombospondin-1, and -2, and 4N1K-peptide in Bladder Cancer.

THBS1 THBS2

3.67e-06339231092423
Pubmed

Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis.

THBS1 THBS2

3.67e-06339219818485
Pubmed

mRNA Expression of thrombospondin 1, 2 and 3 from proximal to distal in human abdominal aortic aneurysm - preliminary report.

THBS1 THBS2

3.67e-06339234669362
Pubmed

Thrombospondin 1 and thrombospondin 2 are expressed as both homo- and heterotrimers.

THBS1 THBS2

3.67e-0633921459996
Pubmed

EWS/FLI1 regulates tumor angiogenesis in Ewing's sarcoma via suppression of thrombospondins.

THBS1 THBS2

3.67e-06339217638877
Pubmed

TSP1 and TSP2 deficiencies affect LOX protein distribution in the femoral diaphysis and pro-peptide removal in marrow-derived mesenchymal stem cells in vitro.

THBS1 THBS2

3.67e-06339230939949
Pubmed

Polymorphisms in thrombospondin genes and myocardial infarction: a case-control study and a meta-analysis of available evidence.

THBS1 THBS2

3.67e-06339218178577
Pubmed

Interactions between CD47 and thrombospondin reduce inflammation.

THBS1 THBS2

3.67e-06339217442977
Pubmed

Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses.

THBS1 THBS2

3.67e-06339219004835
Pubmed

Differential expression of thrombospondin 1, 2, and 3 during murine development.

THBS1 THBS2

3.67e-0633928400410
Pubmed

Thrombospondin is a tight-binding competitive inhibitor of neutrophil elastase.

THBS1 THBS2

3.67e-0633928463250
Pubmed

Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction.

THBS1 THBS2

3.67e-06339212482844
Pubmed

Cocaine Triggers Astrocyte-Mediated Synaptogenesis.

THBS1 THBS2

3.67e-06339233069367
Pubmed

Thrombospondin-1, -2 and -5 have differential effects on vascular smooth muscle cell physiology.

THBS1 THBS2

3.67e-06339226168731
Pubmed

Thrombospondin 2 potentiates notch3/jagged1 signaling.

THBS1 THBS2

7.34e-06439219147503
Pubmed

Protection of neurons from apoptosis by apolipoprotein E-containing lipoproteins does not require lipoprotein uptake and involves activation of phospholipase Cgamma1 and inhibition of calcineurin.

PLCG1 CDH18

7.34e-06439219717566
Pubmed

Cross-platform array screening identifies COL1A2, THBS1, TNFRSF10D and UCHL1 as genes frequently silenced by methylation in melanoma.

THBS1 COL1A2

7.34e-06439222028813
Pubmed

Regulation of spontaneous meiosis resumption in mouse oocytes by various conventional PKC isozymes depends on cellular compartmentalization.

PRKCG PLCG1

7.34e-06439215367584
Pubmed

Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets.

THBS1 THBS2

7.34e-0643926338048
Pubmed

Thrombospondin-1 and thrombospondin-2 mRNA and TSP-1 and TSP-2 protein expression in uterine fibroids and correlation to the genes COL1A1 and COL3A1 and to the collagen cross-link hydroxyproline.

THBS1 THBS2

7.34e-06439218089612
Pubmed

Recognition of the N-terminal modules of thrombospondin-1 and thrombospondin-2 by alpha6beta1 integrin.

THBS1 THBS2

7.34e-06439212909644
Pubmed

Id1 regulates angiogenesis through transcriptional repression of thrombospondin-1.

THBS1 OCLN

7.34e-06439212498716
Pubmed

Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior.

THBS1 THBS2

7.34e-06439211980922
Pubmed

Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity.

THBS1 THBS2

7.34e-06439210900205
Pubmed

Spontaneous bacterial keratitis in CD36 knockout mice.

THBS1 THBS2

7.34e-06439220847111
Pubmed

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.

THBS1 THBS2

1.22e-05539230622267
Pubmed

Protein kinase C regulates the phosphorylation and cellular localization of occludin.

PRKCG OCLN

1.22e-05539211502742
Pubmed

COL3A1, CXCL8, VCAN, THBS2, and COL1A2 are correlated with the onset of biliary atresia.

THBS2 COL1A2

1.22e-05539236930067
Pubmed

Central corneal thickness does not correlate with TonoLab-measured IOP in several mouse strains with single transgenic mutations of matricellular proteins.

THBS1 THBS2

1.22e-05539223806329
Pubmed

Phosphatidylinositol 3-kinase, phosphoinositide-specific phospholipase-Cgamma and protein kinase-C signal myelin phagocytosis mediated by complement receptor-3 alone and combined with scavenger receptor-AI/II in macrophages.

PRKCG PLCG1

1.83e-05639215006698
Pubmed

Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.

THBS1 THBS2 COL1A2

2.77e-055239330389913
Pubmed

Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.

THBS1 THBS2

3.42e-05839224460873
Pubmed

Characterization of mouse thrombospondin 2 sequence and expression during cell growth and development.

THBS1 THBS2

4.39e-0593921371115
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

FAT4 THBS1 PRKCSH PIGG SLC12A2 PLXNB2 HNRNPUL2 HIF1AN

4.68e-05120139835696571
Pubmed

Genome-wide association scan of trait depression.

GRM8 CDH18

6.70e-051139220800221
Pubmed

Transcriptomic analysis of mouse limb tendon cells during development.

THBS2 COL1A2

8.03e-051239225249460
Pubmed

Semaphorin 4D signaling requires the recruitment of phospholipase C gamma into the plexin-B1 receptor complex.

PLCG1 PLXNB2

9.48e-051339219805522
Pubmed

EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland.

PRKCG PLCG1

9.48e-051339212761849
Pubmed

MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis.

OCLN COL1A2

1.11e-041439214627958
Pubmed

Sema3F (Semaphorin 3F) Selectively Drives an Extraembryonic Proangiogenic Program.

THBS1 THBS2

1.11e-041439228729362
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

THBS1 THBS2 COL1A2

1.25e-048639328327460
Pubmed

Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease.

PRKCG THBS1 KCNA5

1.63e-049439320346360
Pubmed

Pericytes are required for blood-brain barrier integrity during embryogenesis.

OCLN COL1A2

2.07e-041939220944625
Pubmed

Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers.

PRKCG CYP2F1

2.07e-04193928432525
Pubmed

Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.

ACSL3 G3BP1 HNRNPUL2 COL1A2

2.33e-0426939430442662
Pubmed

Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.

PRKCG PLCG1

3.33e-042439210843712
Pubmed

Chromosomal mapping in the mouse of eight K(+)-channel genes representing the four Shaker-like subfamilies Shaker, Shab, Shaw, and Shal.

KCNA5 COL1A2

3.91e-04263927905852
Pubmed

Association of candidate gene polymorphisms with chronic kidney disease in Japanese individuals with hypertension.

THBS2 COL1A2

3.91e-042639219282863
Pubmed

Mechanism of HIV-1-TAT induction of interleukin-1beta from human monocytes: Involvement of the phospholipase C/protein kinase C signaling cascade.

PRKCG PLCG1

4.23e-042739220336759
Pubmed

Forkhead box transcription factor FoxC1 preserves corneal transparency by regulating vascular growth.

THBS1 THBS2

5.23e-043039222171010
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

ACSL3 GLMN SLC12A2 OCLN PLXNB2 URGCP

5.91e-0494239631073040
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

THBS1 THBS2 COL1A2

5.93e-0414639327068509
Pubmed

A pancreatic cancer-specific expression profile.

PRKCSH SLC12A2

5.95e-04323928895530
Pubmed

RUNX1 and TGF-β signaling cross talk regulates Ca2+ ion channels expression and activity during megakaryocyte development.

THBS1 COL1A2

7.12e-043539232281291
Pubmed

Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex.

THBS1 THBS2

7.12e-043539235858542
Pubmed

Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalpha-dependent manner.

THBS1 COL1A2

7.96e-043739220236931
Pubmed

Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in mice.

GRM8 CDH18

7.96e-043739216707424
Pubmed

Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves.

THBS1 COL1A2

7.96e-043739238011284
Pubmed

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.

SLC12A2 OCLN G3BP1 PLXNB2

8.12e-0437539432788342
Pubmed

Endothelial Cyp26b1 restrains murine heart valve growth during development.

THBS1 THBS2 COL1A2

8.16e-0416339335364055
Pubmed

Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha.

PRKCG PLCG1

8.40e-043839212482669
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

THBS1 PLXNB2 COL1A2

8.75e-0416739322159717
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

ACSL3 PRKCSH SLC12A2 G3BP1 PLXNB2 HNRNPUL2

9.13e-04102439624711643
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

ACSL3 GLMN PRKCSH PLCG1 G3BP1 HNRNPUL2 VPS13C

9.29e-04142539730948266
Pubmed

The von Hippel-Lindau Cullin-RING E3 ubiquitin ligase regulates APOBEC3 cytidine deaminases.

G3BP1 HNRNPUL2

9.30e-044039234004371
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

THBS1 PLXNB2 COL1A2

1.00e-0317539328071719
InteractionTIMP2 interactions

ACSL3 GNA11 THBS1 THBS2 G3BP1 COL1A2

1.42e-05277396int:TIMP2
GeneFamilyEF-hand domain containing

PRKCSH PLCG1 SPATA21

3.71e-03219263863
GeneFamilySH2 domain containing

PLCG1 SOCS6

9.20e-03101262741
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

SLC12A2 OCLN

2.77e-02181262694
CoexpressionDESCARTES_FETAL_EYE_STROMAL_CELLS

THBS1 THBS2 OMD COL1A2

1.02e-0591394M40180
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 OMD CYP2F1 COL1A2

7.61e-0719639561bee32ca299219f31a30b57124e44e85b798e9f
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-1|TCGA-Thryoid / Sample_Type by Project: Shred V9

CD1B THBS1 THBS2 COL1A2

1.95e-0518339406e4b05d86a7d643569e19575c2c9aa351d33f29
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

THBS2 OMD CYP2F1 COL1A2

1.99e-05184394235890e8b424f4386b6ea52d173d20a00898df73
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMS1 SLC12A2 CYP2F1 COQ8A

2.21e-051893946f1696871a2994fd5f50b7cf4aa00e6d8054b603
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMS1 SLC12A2 G3BP1 VPS13C

2.26e-0519039436e83995021ba16690f84e2077a9e8baec547d05
ToppCell15-Distal-Mesenchymal-Mesenchyme_SERPINF1-high|Distal / Age, Tissue, Lineage and Cell class

THBS2 KCNA5 OMD COL1A2

2.26e-05190394b47472dc9fe6ed99c2365203a3d8a59879e74a70
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMS1 SLC12A2 G3BP1 VPS13C

2.26e-05190394d26be9e1b676f750e716b91ebc3598fac3735612
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-3|TCGA-Ovary / Sample_Type by Project: Shred V9

THBS1 THBS2 OMD COL1A2

2.30e-0519139480d30d8eedb4c70b58440646325bc04c5700803e
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS1 THBS2 OMD COL1A2

2.35e-05192394a8b7c539dc3037071bf068f372e4215563e11de4
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 OMD COL1A2

2.35e-05192394b35f0e422070ba9c7c1d9ff3eace4edc10286cde
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 VPS13C COL1A2

2.35e-0519239411088878043a6ff95ba1970361256a82e434b80a
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS1 THBS2 OMD COL1A2

2.35e-051923942143e1fad2e88b90d668e12af37b2092d379090f
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 CYP2F1 PLXNB2 COL1A2

2.35e-051923940dc1f46e40346ed0b286e53b106a812441575100
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS1 THBS2 OMD COL1A2

2.35e-05192394904c003c4f73b1dfc8243cee02aad2676c515e50
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-3|TCGA-Stomach / Sample_Type by Project: Shred V9

THBS1 THBS2 OMD COL1A2

2.45e-051943942260cd817a6661e5eb6645b0c6786e18fd58371e
ToppCellP28-Mesenchymal-myocytic_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THBS1 THBS2 KCNA5 COL1A2

2.45e-0519439483e45441c74b7f50b6725876b583229280179dc2
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAT4 THBS2 OMD COL1A2

2.45e-05194394439d3f17c1f4736122b330e98add9292c7036a8e
ToppCellASK428-Mesenchymal|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

THBS1 THBS2 OMD COL1A2

2.50e-051953942b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 THBS2 OMD COL1A2

2.50e-05195394f54bc4454270ff06e85596f98199372b50d0179f
ToppCellASK428-Mesenchymal-Fibroblast|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

THBS1 THBS2 OMD COL1A2

2.50e-05195394c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSL3 THBS1 THBS2 VPS13C

2.50e-051953945c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell15-Trachea-Mesenchymal|Trachea / Age, Tissue, Lineage and Cell class

FAT4 THBS2 OMD COL1A2

2.55e-051963947e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 THBS2 OMD COL1A2

2.55e-05196394e7bfd4fb400ae0c473131d0fa306c26be08a6d03
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 THBS2 OMD COL1A2

2.55e-0519639482fad623212d986a7fca3496faf3f8c8f5b83a11
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 CYP2F1 PLXNB2 COL1A2

2.55e-051963942029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 THBS2 OMD COL1A2

2.55e-0519639485e5046f774537684e1443c0fc147d562b7068d0
ToppCellP03-Mesenchymal-myocytic_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THBS1 THBS2 KCNA5 COL1A2

2.60e-05197394079db904a08743b3c555cb7b3f5fb5c978dde25a
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 OMD COL1A2

2.60e-05197394cfd4cc5fb8d7a60dd5c0d2a1a7bad7ba38c19d40
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 THBS2 OMD COL1A2

2.65e-05198394300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCellFetal_29-31_weeks-Mesenchymal|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAT4 THBS1 THBS2 COL1A2

2.65e-0519839421cf4d81386761d09d0f6829c01c198e5524176d
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

FAT4 THBS1 THBS2 COL1A2

2.71e-051993945b9d355795dd03a22f0961dfd143425c367a4654
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FAT4 THBS2 CDH18 COL1A2

2.71e-0519939495d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 THBS2 OMD COL1A2

2.71e-0519939421335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCellwk_15-18-Mesenchymal-Fibroblast-Adventitial_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

THBS1 THBS2 OMD COL1A2

2.71e-051993948de6d7b2067b22cb9b5f01aa56a3803aebc4406d
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 THBS2 OMD COL1A2

2.71e-05199394fb580e9321ddf97c73b2e356cd82523db74a38a2
ToppCellBiopsy_IPF-Mesenchymal-PLIN2+_Fibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

THBS1 THBS2 OMD COL1A2

2.76e-052003942c5626ea8fb4b702d4560117e53edf6cfcf1971e
ToppCellproximal-3-mesenchymal-Adventitial_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

THBS1 THBS2 OMD COL1A2

2.76e-05200394869d45b71efd395d050873db5fee2ed0443d5e6f
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-2,_SCARA5|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

FAT4 THBS2 OMD COL1A2

2.76e-052003942022df85df94ab8cbb4e80e3fe9894c01051c5e0
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 THBS1 THBS2 COL1A2

2.76e-05200394cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell15-Airway|15 / Age, Tissue, Lineage and Cell class

THBS2 KCNA5 OMD COL1A2

2.76e-05200394ba4b8d5becf81351901c2ecac74ffa28e29586f3
ToppCellBronchus_Control_(B.)-Stromal-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

FAT4 THBS2 OMD COL1A2

2.76e-0520039469b41f5fb370aa8840a9ad7919d03ef1e57d1b5b
ToppCellproximal-mesenchymal-Adventitial_Fibroblast|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

THBS1 THBS2 OMD COL1A2

2.76e-0520039458c5870030192b337e7d883044948634fcd17d2c
ToppCellproximal-mesenchymal-Adventitial_Fibroblast-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

THBS1 THBS2 OMD COL1A2

2.76e-0520039405486d86868f6a93429226063cca270f00dd8714
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Cd74|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

OMD CYP2F1 COL1A2

1.39e-041153934c7d78a246f1b44846fb959359515ef185530053
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_ALM_Olfr111_Nxph1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THBS2 NBEAL2 CDH18

1.66e-04122393dba1c647172a11381efcb178a23808161908daa3
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-|Striatum / BrainAtlas - Mouse McCarroll V32

THBS1 THBS2 OMD

2.18e-04134393a3547a68012d879d4dfe80394eace70808722e43
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)|Striatum / BrainAtlas - Mouse McCarroll V32

THBS1 THBS2 OMD

2.18e-041343939458e2d0dbc18d9025b66b59f3ecc2fbc5384940
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THBS1 OMD COL1A2

2.59e-04142393f4e4cde228149d5a536fbf0517ed71d81e296faf
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Met|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KCNA5 GRM8 CDH18

2.75e-041453938abbc781f5f69f039617c29a5589d7b6950c2c40
ToppCellCOVID-19_Moderate-multiplets|COVID-19_Moderate / disease group, cell group and cell class

PLCG1 OMD NBEAL2

2.86e-04147393baf15c773d7751bc6f64d4974a22738626f2b3ff
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Krt80_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PRKCG GRM8 CDH18

3.10e-04151393f50c5ae9dae507df750df25e151b58685fec70ce
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_AB-8|TCGA-Thymus / Sample_Type by Project: Shred V9

FAT4 OMD SLC12A2

3.10e-041513935906562efd36fbcb91f96e0a0d3a8fe999ba1e79
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

OMD AJM1 GLRA1

3.10e-04151393ea62e92ccb984f44559b434f35c1c4450767c8f1
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Thalamus / BrainAtlas - Mouse McCarroll V32

THBS2 OMD COL1A2

3.22e-04153393e9c6fb5c41adb6595c66c3a917fe455348279e54
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Thalamus / BrainAtlas - Mouse McCarroll V32

THBS2 OMD COL1A2

3.22e-04153393b8b5ff7d2feea3e3a352fb5530e49f639fe1ff88
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP|Thalamus / BrainAtlas - Mouse McCarroll V32

THBS2 OMD COL1A2

3.22e-041533932513edfae62a44e51d3556675a096723194c966c
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Tall_Cell-1|TCGA-Thryoid / Sample_Type by Project: Shred V9

CD1B THBS2 COL1A2

3.41e-0415639345a05c7a45a3ec8551818ab67f18b3b9553934c1
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC12A2 GRM8 COL1A2

3.54e-0415839332c95c1bc9e50fccd6d06e828f29258fc5e568cb
ToppCellAdult-Mesenchymal-myofibroblast_cell-D122|Adult / Lineage, Cell type, age group and donor

THBS2 OMD COL1A2

3.54e-04158393410fa08c9d880d27e80ec939fa5ba5a41dcb31ab
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

THBS2 OMD COL1A2

3.60e-04159393cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THBS1 OMD COL1A2

3.60e-0415939334c90711c5857cf6ada7b3acff99f1d48c7caf29
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

THBS2 OMD COL1A2

3.60e-0415939392049a8d8fc9997d8d0d76500c72596a9b2394e0
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3-6_VIP_KCTD13|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 VWDE GLRA1

3.81e-04162393fd9c443a04445811f921f1b3ecd9b49febcda675
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PRKCG GRM8 CDH18

3.81e-0416239358da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

CATSPERD GRM8 CDH18

3.88e-0416339319c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell343B-Fibroblasts-Fibroblast-D-|343B / Donor, Lineage, Cell class and subclass (all cells)

THBS2 OMD COL1A2

3.88e-041633938d2b2119c6b3d5b677da6f377fd85146590e1246
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Brinp3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PRKCG GRM8 CDH18

3.88e-04163393b0aa4a620bd58011225b42ea6dda04e3101ba342
ToppCell343B-Fibroblasts-Fibroblast-D|343B / Donor, Lineage, Cell class and subclass (all cells)

THBS2 OMD COL1A2

3.88e-04163393acfb2ece6202479e615d54fd3ecb8b4a571b5a18
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

THBS2 OMD COL1A2

4.02e-04165393570483b43ccb5831feec9337b4664814431d40b1
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

THBS2 OMD COL1A2

4.02e-041653932026a9a07f4d314cc05c167e491312b373468e46
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 GRM8 COL1A2

4.16e-04167393805129f887078340b260aa136b0ba19f2bd6ea03
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKCG GRM8 GARIN5A

4.16e-04167393e0f2509e86302eca8352821bce12597f6c51fc24
ToppCellfacs-Lung-EPCAM-24m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKCG GRM8 GARIN5A

4.16e-04167393b25646b6653cd8814dbeae4c74ce899ede105200
ToppCellAdult-Mesenchymal-myofibroblast_cell|Adult / Lineage, Cell type, age group and donor

THBS2 OMD COL1A2

4.16e-04167393d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 GRM8 COL1A2

4.16e-0416739331cf8bf2eb523f6e7e319620648ff37fc09e2601
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 GRM8 COL1A2

4.16e-041673933acb18428d1d33ad430c2fd031b1a91baee3c01d
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

THBS1 THBS2 COL1A2

4.23e-04168393aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP|Hippocampus / BrainAtlas - Mouse McCarroll V32

THBS2 OMD COL1A2

4.23e-0416839326aa96b2b547d11941cb803995ea3d302ee0518c
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOCS6 SLC12A2 CYP2F1

4.23e-04168393de0b00bc405c898d08a06b2e585fb62c0ab9a66e
ToppCell367C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|367C / Donor, Lineage, Cell class and subclass (all cells)

THBS2 OMD COL1A2

4.31e-0416939347fd4adfe54777e69a0fabf8bd34f26223f63275
ToppCell367C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|367C / Donor, Lineage, Cell class and subclass (all cells)

THBS2 OMD COL1A2

4.31e-04169393e09259d62cd3e42f0919f231ed1164db59b0b6c3
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THBS2 OMD COL1A2

4.31e-04169393031465190cd3623a25ef2b868daab8d932c8ff08
ToppCelldroplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 OMD COL1A2

4.38e-0417039310e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 THBS1 KCNA5

4.46e-04171393972fab891135bd755d5526cbc5a963200067b0a6
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THBS2 OMD COL1A2

4.46e-0417139315cb4670ff4234ac46aea8a5911138d6913c4482
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 THBS1 KCNA5

4.46e-041713932a77ed79c6f2e700e789c80451a70ecb31639719
ToppCelldroplet-Fat-Scat-18m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 PLXNB2 COL1A2

4.53e-041723938a4a5ad65eec92ce4fa45c5aa01c28666307455b
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 THBS2 COL1A2

4.61e-041733931f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCellwk_08-11-Mesenchymal-Fibroblast-Airway_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

THBS2 CDH18 COL1A2

4.61e-04173393b23b408acc29a667cce104429afef1a6cf2720a5
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Tall_Cell|TCGA-Thryoid / Sample_Type by Project: Shred V9

CD1B THBS2 COL1A2

4.61e-041733932e9dc137f3675eee07f941eb4cfcaf24a83ab0fb
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 THBS2 COL1A2

4.77e-041753931799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

THBS2 OMD COL1A2

4.85e-041763932e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

THBS2 OMD COL1A2

4.85e-04176393f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC12A2 CYP2F1 VWDE

4.93e-04177393a4c001a8e44142babf9f24dfe6f7b73a70b11b16
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THBS2 OMD COL1A2

4.93e-041773934197cf2b1e743230c821f422836fa5991b155a52
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC12A2 CYP2F1 VWDE

4.93e-04177393363e07b0f347f3716d530a28ead854b98e27d37c
ToppCellPND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THBS1 PIGG NBEAL2

5.01e-0417839363f5880a5b514e20ef2c07a6a9cb8df34e6cede5
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

THBS1 THBS2 COL1A2

5.01e-04178393142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

OMD VWDE COL1A2

5.01e-041783938f31b3fac51591f7f2bcb898c07708b3e9f93a16
ToppCellPND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THBS1 PIGG NBEAL2

5.01e-0417839382c84f8b8a7e6a3d3be3351b348a37143279c100
DrugVerteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A

ACSL3 THBS1 PRKCSH SLC12A2 PLXNB2

7.88e-061613953556_DN
DrugGi-2

PRKCG GNA11 PLCG1 GRM8 HNRNPUL2

1.99e-05195395CID011957432
Drug2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide

THBS1 THBS2 COL1A2

2.02e-0531393ctd:C577942
DrugTrifluoperazine dihydrochloride [440-17-5]; Down 200; 8.4uM; HL60; HT_HG-U133A

N4BP2L1 SOCS6 OMD HIF1AN URGCP

2.09e-051973952389_DN
DrugAtractyloside potassium salt [102130-43-8]; Up 200; 5uM; MCF7; HT_HG-U133A

THBS1 KCNA5 OMD GRM8 PARP8

2.14e-051983954717_UP
Diseasemiddle cerebral artery infarction (is_marker_for)

PRKCG SLC12A2

1.37e-062352DOID:3525 (is_marker_for)
Diseasemaleate measurement, Alpha ketoglutarate measurement, fumarate measurement

GRM8 PARP8

7.47e-0511352EFO_0010457, EFO_0010480, EFO_0010509
DiseaseMicroangiopathy, Diabetic

THBS1 THBS2

1.62e-0416352C0025945
DiseaseDiabetic Angiopathies

THBS1 THBS2

1.62e-0416352C0011875
Diseasevisual epilepsy (implicated_via_orthology)

SLC12A2 GRM8

7.49e-0434352DOID:11832 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

KCNA5 SLC12A2 GRM8

9.51e-04163353DOID:1826 (implicated_via_orthology)
DiseaseInherited neuropathies

PRKCG COQ8A

1.04e-0340352C0598589
Diseasediabetic retinopathy (biomarker_via_orthology)

THBS1 OCLN

1.31e-0345352DOID:8947 (biomarker_via_orthology)
Diseaseneuroimaging measurement

THBS1 PRKCSH KCNA5 G3BP1 PLXNB2 HIF1AN

1.47e-031069356EFO_0004346
DiseaseHepatic fibrosis

CYP2F1 GRM8

1.55e-0349352HP_0001395
DiseaseCirrhosis

THBS1 COL1A2

1.62e-0350352C1623038
DiseaseFibrosis

THBS1 COL1A2

1.62e-0350352C0016059
Diseaseobesity (implicated_via_orthology)

GNA11 FAT4 PLXNB2

2.10e-03215353DOID:9970 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
EFYDPGFQGQQSSED

CATSPERD

546

Q86XM0
DKDFGPNGEVRYSFE

FAT4

1126

Q6V0I7
FFYTEEPQGFRGSFA

AJM1

281

C9J069
YIFGFAREVQDFAGD

CD1B

91

P29016
QGEEFSGRGDYPAFF

CYP2F1

91

P24903
DDFRQPRYSSGGNFE

OCLN

361

Q16625
TRFFFVYEDGQVGDA

PARP8

816

Q8N3A8
QVDFDNPDYERFPNF

HIF1AN

241

Q9NWT6
QEISFDFGPNGEFAY

PRKCSH

396

P14314
QQFVAAFEDGPYVFF

PLXNB2

216

O15031
DFSRPQLGEDEFSYG

HNRNPUL2

321

Q1KMD3
QSGEFDQFRDFPIFE

GARIN5A

101

Q6IPT2
DQADFQGFTYVNPDF

PRKCG

666

P05129
FNENGDAPGRYDIFQ

GRM8

461

O00222
GYDGDFYRADQPRSA

COL1A2

1111

P08123
NEYFFDRNRPSFDGI

KCNA5

161

P22460
FRYQDEVFGGFVTEP

G3BP1

131

Q13283
YFPEFDGPQRDAQAA

GNA11

291

P29992
EYFAENFGGPEGEFH

COQ8A

66

Q8NI60
DFANGPRFNFFLDER

CDH18

516

Q13634
DDDYQTGFPFRQNVD

OMD

36

Q99983
FEQSEEGGNDPFRYF

GLMN

226

Q92990
FRSYFEIFNGPGEVD

SPATA21

226

Q7Z572
RYDFGFPQEVFDGNQ

IFNA16

56

P05015
QEDEAGEGRFNFSAY

GLRA1

361

P23415
YFPDFLENQNGFDLG

NBEAL2

2221

Q6ZNJ1
CFQQFPEGLFYEFEG

LIMS1

41

P48059
SYEDVFVRAFNFGNG

ACSL3

136

O95573
FRYGDGTNEAQDNDF

URGCP

51

Q8TCY9
ENFEYQFVAFDPEGS

VWDE

1111

Q8N2E2
TERDDDYAGFVFGYQ

THBS1

1016

P07996
FGYKSEIFNENFGPD

SLC12A2

466

P55011
EGSFESRYQQPFEDF

PLCG1

1246

P19174
FYEPFQGAVQGPEEF

VPS13C

3441

Q709C8
ELYGADFVFGEDFQP

TTLL3

451

Q9Y4R7
VNTDRDDDYAGFVFG

THBS2

1016

P35442
QETYRNYFLGDDGEP

PIGG

591

Q5H8A4
SNGRFSFYEQPDVEG

SOCS6

436

O14544
DFFFREDGAYEFNPD

N4BP2L1

76

Q5TBK1