Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	pseudopodium	ACTN4 ACTN1 ACTN3	1.29e-05	18	54	3	GO:0031143
GeneOntologyCellularComponent	NLS-dependent protein nuclear import complex	KPNA7 MYBBP1A	2.91e-04	10	54	2	GO:0042564
GeneOntologyCellularComponent	cortical cytoskeleton	ACTN4 ACTN1 ACTN3 BSN	3.45e-04	129	54	4	GO:0030863
GeneOntologyCellularComponent	nucleocytoplasmic transport complex	KPNA7 MYBBP1A	4.25e-04	12	54	2	GO:0031074
GeneOntologyCellularComponent	Z disc	ACTN4 ACTN1 GRIN2B ACTN3	6.25e-04	151	54	4	GO:0030018
GeneOntologyCellularComponent	I band	ACTN4 ACTN1 GRIN2B ACTN3	8.90e-04	166	54	4	GO:0031674
Domain	EF-hand_Ca_insen	ACTN4 ACTN1 ACTN3	4.54e-07	6	54	3	IPR014837
Domain	EFhand_Ca_insen	ACTN4 ACTN1 ACTN3	4.54e-07	6	54	3	PF08726
Domain	Actinin_actin-bd_CS	ACTN4 ACTN1 ACTN3	3.88e-05	23	54	3	IPR001589
Domain	Spectrin	ACTN4 ACTN1 ACTN3	3.88e-05	23	54	3	PF00435
Domain	ACTININ_2	ACTN4 ACTN1 ACTN3	3.88e-05	23	54	3	PS00020
Domain	ACTININ_1	ACTN4 ACTN1 ACTN3	3.88e-05	23	54	3	PS00019
Domain	Spectrin_repeat	ACTN4 ACTN1 ACTN3	7.92e-05	29	54	3	IPR002017
Domain	Spectrin/alpha-actinin	ACTN4 ACTN1 ACTN3	1.07e-04	32	54	3	IPR018159
Domain	SPEC	ACTN4 ACTN1 ACTN3	1.07e-04	32	54	3	SM00150
Domain	Drf_GBD	FMNL3 DIAPH3	2.92e-04	9	54	2	PF06371
Domain	FH3_dom	FMNL3 DIAPH3	2.92e-04	9	54	2	IPR010472
Domain	GTPase-bd	FMNL3 DIAPH3	2.92e-04	9	54	2	IPR010473
Domain	Drf_FH3	FMNL3 DIAPH3	2.92e-04	9	54	2	PF06367
Domain	Drf_FH3	FMNL3 DIAPH3	2.92e-04	9	54	2	SM01139
Domain	Drf_GBD	FMNL3 DIAPH3	2.92e-04	9	54	2	SM01140
Domain	GBD/FH3_dom	FMNL3 DIAPH3	4.44e-04	11	54	2	IPR014768
Domain	GBD_FH3	FMNL3 DIAPH3	4.44e-04	11	54	2	PS51232
Domain	FH2	FMNL3 DIAPH3	8.41e-04	15	54	2	PS51444
Domain	FH2_Formin	FMNL3 DIAPH3	8.41e-04	15	54	2	IPR015425
Domain	FH2	FMNL3 DIAPH3	8.41e-04	15	54	2	PF02181
Domain	FH2	FMNL3 DIAPH3	8.41e-04	15	54	2	SM00498
Domain	CH	ACTN4 ACTN1 ACTN3	8.79e-04	65	54	3	SM00033
Domain	CH	ACTN4 ACTN1 ACTN3	1.09e-03	70	54	3	PF00307
Domain	EFh	ACTN4 ACTN1 ACTN3 SMOC2	1.12e-03	158	54	4	SM00054
Domain	-	ACTN4 ACTN1 ACTN3	1.14e-03	71	54	3	1.10.418.10
Domain	CH	ACTN4 ACTN1 ACTN3	1.23e-03	73	54	3	PS50021
Domain	CH-domain	ACTN4 ACTN1 ACTN3	1.33e-03	75	54	3	IPR001715
Domain	CNMP_BINDING_1	CNBD1 PNPLA6	3.85e-03	32	54	2	PS00888
Domain	CNMP_BINDING_2	CNBD1 PNPLA6	3.85e-03	32	54	2	PS00889
Domain	SNF2_N	ATRX CHD6	3.85e-03	32	54	2	IPR000330
Domain	SNF2_N	ATRX CHD6	3.85e-03	32	54	2	PF00176
Domain	cNMP_binding	CNBD1 PNPLA6	4.34e-03	34	54	2	PF00027
Domain	EF_HAND_2	ACTN4 ACTN1 ACTN3 SMOC2	4.44e-03	231	54	4	PS50222
Domain	EF_hand_dom	ACTN4 ACTN1 ACTN3 SMOC2	4.51e-03	232	54	4	IPR002048
Domain	TPR-like_helical_dom	CCNF ST13P4 SMG5 IFIT2	4.58e-03	233	54	4	IPR011990
Domain	cNMP-bd_dom	CNBD1 PNPLA6	4.59e-03	35	54	2	IPR000595
Domain	CNMP_BINDING_3	CNBD1 PNPLA6	4.59e-03	35	54	2	PS50042
Domain	cNMP-bd-like	CNBD1 PNPLA6	5.40e-03	38	54	2	IPR018490
Domain	-	ACTN4 ACTN1 ACTN3 SMOC2	6.82e-03	261	54	4	1.10.238.10
Domain	-	CNBD1 PNPLA6	8.50e-03	48	54	2	2.60.120.10
Pathway	REACTOME_NEPHRIN_FAMILY_INTERACTIONS	ACTN4 ACTN1 ACTN3	4.18e-05	23	42	3	M913
Pathway	WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY	DSG2 ACTN4 ACTN1 ACTN3	6.73e-05	74	42	4	M39462
Pathway	KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC	DSG2 ACTN4 ACTN1 ACTN3	6.73e-05	74	42	4	M16376
Pubmed	α-Actinin-3 deficiency is associated with reduced bone mass in human and mouse.	ACTN4 ACTN1 ACTN3	3.54e-09	3	54	3	21784188
Pubmed	Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis.	ACTN4 ACTN1 ACTN3	1.41e-08	4	54	3	16807302
Pubmed	Alpha-actinin and vinculin in human neutrophils: reorganization during adhesion and relation to the actin network.	ACTN4 ACTN1 ACTN3	1.41e-08	4	54	3	1629252
Pubmed	The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin.	ACTN4 ACTN1 ACTN3	3.53e-08	5	54	3	12837758
Pubmed	Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interaction.	ACTN4 ACTN1 ACTN3	3.53e-08	5	54	3	19943616
Pubmed	Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner.	ACTN4 ACTN1 ACTN3	3.53e-08	5	54	3	15841212
Pubmed	Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.	ACTN4 ACTN1 ACTN3	7.05e-08	6	54	3	18425115
Pubmed	The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway.	ACTN4 ACTN1 ACTN3	7.05e-08	6	54	3	22693585
Pubmed	CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function.	ACTN4 ACTN1 ACTN3	1.97e-07	8	54	3	20215401
Pubmed	Mice deficient in alpha-actinin-4 have severe glomerular disease.	ACTN4 ACTN1 ACTN3	1.97e-07	8	54	3	12782671
Pubmed	Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology.	ACTN4 ACTN1 ACTN3	4.21e-07	10	54	3	20368620
Pubmed	Phosphorylation of mouse LASP-1 on threonine 156 by cAMP- and cGMP-dependent protein kinase.	ACTN4 ACTN1 ACTN3	7.71e-07	12	54	3	15465019
Pubmed	Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy.	ACTN4 ACTN1 ACTN3	1.59e-06	15	54	3	11440986
Pubmed	USP7 controls NGN3 stability and pancreatic endocrine lineage development.	MYBBP1A PNPLA6 GTF3C1 GRIN2B	2.07e-06	58	54	4	37117185
Pubmed	α-actinin1 and 4 tyrosine phosphorylation is critical for stress fiber establishment, maintenance and focal adhesion maturation.	ACTN4 ACTN1	2.37e-06	2	54	2	23454549
Pubmed	Distinct forms of the actin cross-linking protein α-actinin support macropinosome internalization and trafficking.	ACTN4 ACTN1	2.37e-06	2	54	2	34010028
Pubmed	Alpha-actinin 1 and alpha-actinin 4: contrasting roles in the survival, motility, and RhoA signaling of astrocytoma cells.	ACTN4 ACTN1	2.37e-06	2	54	2	20156433
Pubmed	Cell type-dependent mechanisms for formin-mediated assembly of filopodia.	FMNL3 DIAPH3	2.37e-06	2	54	2	26446836
Pubmed	An analysis of splicing, actin-binding properties, heterodimerization and molecular interactions of the non-muscle α-actinins.	ACTN4 ACTN1	2.37e-06	2	54	2	23557398
Pubmed	Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology.	ACTN4 ACTN1	2.37e-06	2	54	2	20037648
Pubmed	HAMLET binding to α-actinin facilitates tumor cell detachment.	ACTN4 ACTN1	2.37e-06	2	54	2	21408150
Pubmed	Actinin-1 and actinin-4 play essential but distinct roles in invadopodia formation by carcinoma cells.	ACTN4 ACTN1	2.37e-06	2	54	2	28797528
Pubmed	Differential binding of cross-reactive anti-DNA antibodies to mesangial cells: the role of alpha-actinin.	ACTN4 ACTN1	7.09e-06	3	54	2	16751418
Pubmed	Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins.	ACTN4 ACTN1	7.09e-06	3	54	2	23890175
Pubmed	Evidence of a functional role for interaction between ICAM-1 and nonmuscle alpha-actinins in leukocyte diapedesis.	ACTN4 ACTN1	7.09e-06	3	54	2	16951376
Pubmed	Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin.	ACTN4 ACTN3	7.09e-06	3	54	2	8104223
Pubmed	The human non-muscle alpha-actinin protein encoded by the ACTN4 gene suppresses tumorigenicity of human neuroblastoma cells.	ACTN4 ACTN3	7.09e-06	3	54	2	10656685
Pubmed	Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2.	ACTN4 ACTN1 ACTN3	1.01e-05	27	54	3	36899856
Pubmed	Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors.	ACTN4 ACTN1	1.42e-05	4	54	2	22351778
Pubmed	CLP-36 PDZ-LIM protein associates with nonmuscle alpha-actinin-1 and alpha-actinin-4.	ACTN4 ACTN1	1.42e-05	4	54	2	10753915
Pubmed	Interactions of a hemidesmosome component and actinin family members.	ACTN4 ACTN1	1.42e-05	4	54	2	11739652
Pubmed	Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation.	ACTN4 ACTN1	1.42e-05	4	54	2	23515331
Pubmed	An interaction between alpha-actinin and the beta 1 integrin subunit in vitro.	ACTN4 ACTN1	1.42e-05	4	54	2	2116421
Pubmed	Structural dynamics of alpha-actinin-vinculin interactions.	ACTN4 ACTN1	1.42e-05	4	54	2	15988023
Pubmed	The relationship among nephrin, podocin, CD2AP, and alpha-actinin might not be a true 'interaction' in podocyte.	ACTN4 ACTN1	2.36e-05	5	54	2	16501493
Pubmed	Habituation in prepulse inhibition is affected by a polymorphism on the NMDA receptor 2B subunit gene (GRIN2B).	GRIN2B TPH1	3.54e-05	6	54	2	20421849
Pubmed	Yeast two-hybrid screening using constitutive-active caspase-7 as bait in the identification of PA28gamma as an effector caspase substrate.	CASP6 PSME3	3.54e-05	6	54	2	11859414
Pubmed	The protein-tyrosine phosphatase SHP-1 regulates the phosphorylation of alpha-actinin.	ACTN4 ACTN1	3.54e-05	6	54	2	15070900
Pubmed	A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins.	ACTN4 ACTN1 ACTN3	4.79e-05	45	54	3	22114352
Pubmed	Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins.	ACTN4 ACTN1	4.94e-05	7	54	2	11724819
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MYBBP1A GTF3C1 ATRX COL20A1 ACTN4 CHD6 ACTN1 ACTN3 DIAPH3 BSN	6.58e-05	1442	54	10	35575683
Pubmed	Genetic and physical mapping of the dreher locus on mouse chromosome 1.	ILDR2 TADA1	8.46e-05	9	54	2	10444330
Pubmed	Activation of cannabinoid type 2 receptors inhibits HIV-1 envelope glycoprotein gp120-induced synapse loss.	IL1R2 GRIN2B	8.46e-05	9	54	2	21670103
Pubmed	Calsarcins, a novel family of sarcomeric calcineurin-binding proteins.	ACTN1 ACTN3	8.46e-05	9	54	2	11114196
Pubmed	Superresolution imaging of chemical synapses in the brain.	GRIN2B BSN	8.46e-05	9	54	2	21144999
Pubmed	Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal.	DOCK4 SOX8 SMOC2	8.77e-05	55	54	3	19884258
Pubmed	Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.	RAP1GAP2 SMG5 DIAPH3 IFIT2	1.17e-04	161	54	4	32572027
Pubmed	Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population.	GRIN2B BSN TPH1	1.25e-04	62	54	3	19367581
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ATRX KLHL7 RAP1GAP2 DYNC2I1 ACTN4 CHD6 SMG5 ACTN1 GRIN2B	1.48e-04	1285	54	9	35914814
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	MYBBP1A GTF3C1 ATRX JMJD6 DPCD ACTN1	1.74e-04	533	54	6	30554943
Pubmed	Stability of the cancer target DDIAS is regulated by the CHIP/HSP70 pathway in lung cancer cells.	ACTN4 ACTN1	1.83e-04	13	54	2	28079882
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	MYBBP1A GTF3C1 DSG2 PSME3 ACTN1 DIAPH3	2.05e-04	549	54	6	38280479
Pubmed	Mechanical regulation of glycolysis via cytoskeleton architecture.	ACTN4 ACTN1	2.13e-04	14	54	2	32051585
Pubmed	Expression of multiple formins in adult tissues and during developmental stages of mouse brain.	FMNL3 DIAPH3	2.13e-04	14	54	2	26272686
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MYBBP1A ADPRS PNPLA6 GTF3C1 ACTN4 PSME3 ACTN1 KIF18B ANKRD52	2.18e-04	1353	54	9	29467282
Pubmed	Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.	IL1R2 CASP6 ACTN4 ACTN1 GRIN2B	2.77e-04	371	54	5	25241761
Pubmed	Targeting USP9X-AMPK Axis in ARID1A-Deficient Hepatocellular Carcinoma.	ACTN4 ACTN1	2.80e-04	16	54	2	35390516
Pubmed	Interaction of zonula occludens-1 (ZO-1) with alpha-actinin-4: application of functional proteomics for identification of PDZ domain-associated proteins.	ACTN4 ACTN1	2.80e-04	16	54	2	16944923
Pubmed	Human transcription factor protein interaction networks.	ST13P4 MYBBP1A TADA1 GTF3C1 ATRX CHD6 SMG5 PSME3 VGLL4	3.26e-04	1429	54	9	35140242
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ILDR2 MYBBP1A PNPLA6 SCRN1 ACTN4 ACTN1 GRIN2B ACTN3 BSN	3.29e-04	1431	54	9	37142655
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	GTF3C1 DSG2 ACTN4 PSME3 ACTN1	3.86e-04	399	54	5	37536630
Pubmed	Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production.	PPY TPH1	3.98e-04	19	54	2	31668390
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	FMNL3 TADA1 GTF3C1 ACTN4 KIF18B	4.37e-04	410	54	5	26949251
Pubmed	Can we predict top-level sports performance in power vs endurance events? A genetic approach.	DSG2 ACTN3	4.42e-04	20	54	2	20459474
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	GTF3C1 CHD6 DIAPH3 SOX8 ANKRD52	4.77e-04	418	54	5	34709266
Pubmed	Proteomic analysis of a detergent-resistant membrane skeleton from neutrophil plasma membranes.	ACTN4 ACTN1	4.88e-04	21	54	2	12202484
Pubmed	The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas.	PPY SOX8	4.88e-04	21	54	2	16306355
Pubmed	Proteomic identification of the TRAF6 regulation of vacuolar ATPase for osteoclast function.	ACTN4 ACTN1	4.88e-04	21	54	2	16196101
Pubmed	Prohibitin regulates TGF-beta induced apoptosis as a downstream effector of Smad-dependent and -independent signaling.	GTF3C1 SMG5	4.88e-04	21	54	2	19725029
Pubmed	Transcription profile in mouse four-cell, morula, and blastocyst: Genes implicated in compaction and blastocoel formation.	PARD6G ACTN4	5.86e-04	23	54	2	16998848
Pubmed	Pak3 promotes cell cycle exit and differentiation of β-cells in the embryonic pancreas and is necessary to maintain glucose homeostasis in adult mice.	PPY TPH1	6.39e-04	24	54	2	24163148
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	MYBBP1A PNPLA6 GTF3C1 DSG2 KLHL7 RER1 ACTN4 ACTN1	6.76e-04	1257	54	8	36526897
Pubmed	ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.	ATRX SMOC2 BSN	7.34e-04	113	54	3	34474245
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	MYBBP1A DSG2 ACTN4 ACTN1	8.75e-04	274	54	4	34244482
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	MYBBP1A ATRX KLHL7 DYNC2I1 ACTN4 ACTN1 KIF18B CWC25	9.33e-04	1321	54	8	27173435
Pubmed	Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions.	ACTN4 ACTN1	1.07e-03	31	54	2	14630798
Pubmed	E3 Ubiquitin Ligase UBR5 Promotes the Metastasis of Pancreatic Cancer via Destabilizing F-Actin Capping Protein CAPZA1.	ACTN4 ACTN1	1.07e-03	31	54	2	33777788
Pubmed	HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages.	ACTN4 ACTN1	1.14e-03	32	54	2	27114546
Pubmed	Convergence of the insulin and serotonin programs in the pancreatic β-cell.	PPY TPH1	1.29e-03	34	54	2	22013016
Pubmed	Proteomic analysis reveals novel binding partners of MIP-T3 in human cells.	ACTN4 ACTN1	1.29e-03	34	54	2	20391533
Pubmed	Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.	IL1R2 ACTN1	1.36e-03	35	54	2	23969696
Pubmed	Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart.	ACTN1 FGF16	1.44e-03	36	54	2	19411759
Pubmed	Nuclear Functions of Nucleolin through Global Proteomics and Interactomic Approaches.	MYBBP1A GTF3C1 ACTN4	1.51e-03	145	54	3	27049334
Pubmed	Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC).	ACTN4 ACTN1	1.52e-03	37	54	2	16396496
Cytoband	1q24.1	ILDR2 TADA1	3.69e-04	24	54	2	1q24.1
Cytoband	17q21	PPY PSME3	2.53e-03	63	54	2	17q21
Cytoband	16p13.3	CCNF SOX8 RAB26	3.01e-03	244	54	3	16p13.3
GeneFamily	Actinins	ACTN4 ACTN1 ACTN3	2.21e-08	4	33	3	1112
Coexpression	GSE6092_UNSTIM_VS_IFNG_STIM_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_UP	KPNA7 CASP6 PARD6G DIAPH3 KIF18B IFIT2	3.49e-06	200	54	6	M6713
ToppCell	PCW_13-14-Neuronal-Neuronal_SCP\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ILDR2 TRPM3 COL20A1 GRIN2B SOX8	2.19e-06	177	53	5	621dd82f1393c961d4dd7a615aa52c9df9e36336
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	GTF3C1 JMJD6 RAP1GAP2 ACTN4 IFIT2	3.79e-06	198	53	5	faeef749a4b4bdc7f3edb6923e0e248e8b92c9d0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_low-phase\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HS6ST2 ZNF221 DIAPH3 KIF18B	2.61e-05	144	53	4	f6061dd965a2b2fe6ad864f8aecc06d2e74881ce
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYBBP1A CASP6 ANKRD52	3.27e-05	52	53	3	d654e2b77c53ed5319015598b68a20bf4416380c
ToppCell	PCW_13-14-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ILDR2 TRPM3 COL20A1 GRIN2B	3.57e-05	156	53	4	8353f98e7d393d4299ed1da8f66cfbc7176df1b5
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAP1GAP2 ACTN3 RAB26 TPH1	3.94e-05	160	53	4	6c89a2e4189e4f2b6b09b66c6aae6653785ab2f8
ToppCell	368C-Fibroblasts-Fibroblast-E\|368C / Donor, Lineage, Cell class and subclass (all cells)	ACTN3 SMOC2 KIF18B FGF16	4.13e-05	162	53	4	e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell	368C-Fibroblasts-Fibroblast-E-\|368C / Donor, Lineage, Cell class and subclass (all cells)	ACTN3 SMOC2 KIF18B FGF16	4.13e-05	162	53	4	ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNF NATD1 ACTN4 KIF18B	4.23e-05	163	53	4	3efbbdc9cb2613bb76d8c2f07cd4ec1a2c51a622
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	TRPM3 SOX8 BSN IFIT2	4.34e-05	164	53	4	362c16ed7fb37bf16601fd5e059d3f3e2ed692b4
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRPM3 RAP1GAP2 RAB26 TPH1	4.44e-05	165	53	4	4b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CCNF ACTN3 DIAPH3 KIF18B	4.44e-05	165	53	4	a5c3af634d2698f9a01cf074791756b7669f9fff
ToppCell	Dividing_Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	CCNF ATRX DIAPH3 KIF18B	4.55e-05	166	53	4	c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TRPM3 COL20A1 HS6ST2 SOX8	4.65e-05	167	53	4	49b19159c62d33d65ed1e59a148c11ae902fd41c
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRPM3 COL20A1 GRIN2B SOX8	4.76e-05	168	53	4	af82e07d1eec51fc6530155f37addbce6221885d
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPY RAP1GAP2 RAB26 TPH1	4.76e-05	168	53	4	38ba7737ae0afffcbd3aa499403e83c24a922127
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAP1GAP2 ACTN3 RAB26 TPH1	4.76e-05	168	53	4	17d46f993dc4ae22b8087808582aba77f5c61892
ToppCell	droplet-Marrow-nan-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GTF3C1 DIAPH3 IFIT2 ANKRD52	4.87e-05	169	53	4	5f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCNF DIAPH3 SOX8 KIF18B	5.22e-05	172	53	4	e495efd25aec60b97ac2b5aa861651bd73174a17
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAP1GAP2 BSN RAB26 TPH1	5.34e-05	173	53	4	07798461d12d04f3dabff03481c999cb07c5af2f
ToppCell	10x5'-Lung-Lymphocytic_NK-Cycling_NK\|Lung / Manually curated celltypes from each tissue	ILDR2 DIAPH3 KIF18B RAB26	5.34e-05	173	53	4	d815832f89f70662706620e3b03ebb1dabec0034
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPY RAP1GAP2 RAB26 TPH1	5.34e-05	173	53	4	46ed379571385684145b5cb6dd4ae340ac546e64
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRPM3 COL20A1 GRIN2B SOX8	5.46e-05	174	53	4	412ccc099028a372b9d953363984c2da54b2187f
ToppCell	COVID-19-kidney-Podocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ILDR2 CCBE1 PARD6G GRIN2B	5.58e-05	175	53	4	a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCell	RSV-Healthy-2\|Healthy / Virus stimulation, Condition and Cluster	ILDR2 RAP1GAP2 PARD6G DIAPH3	5.58e-05	175	53	4	c47440c0b0513e67fe13b85f10dd8a8d42d0e9a3
ToppCell	RSV-Healthy-2\|RSV / Virus stimulation, Condition and Cluster	ILDR2 RAP1GAP2 PARD6G DIAPH3	5.58e-05	175	53	4	0e97189585b7afaf3bd622c3ef10c86412393829
ToppCell	droplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCNF DIAPH3 SOX8 KIF18B	5.71e-05	176	53	4	b17317ac41d3215db55a38cbd3366c0947f7a2a3
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPY RAP1GAP2 BSN TPH1	5.71e-05	176	53	4	2e1003dc373b14d27f0464d980453fdcfc1005f0
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAP1GAP2 ACTN3 RAB26 TPH1	5.83e-05	177	53	4	5bccc7a74019eae8afd977a9c9134d884857ac27
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CILP2 HS6ST2 SCRN1 SOX8	5.96e-05	178	53	4	445fb243d738a34794d66f34b92dde1f3ea6738e
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL20A1 RER1 VGLL4 SOX8	5.96e-05	178	53	4	b1357ceb84b83fab53c0394c1af73cbd009f571a
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related-Microfold_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK4 TRPM3 GRIN2B SOX8	6.09e-05	179	53	4	7aa4137f672dadb3be92009cde6e0ea60a15372d
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAP1GAP2 ACTN3 RAB26 TPH1	6.09e-05	179	53	4	ec7c38464863ac3744a8d4880f49421914892339
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAP1GAP2 ACTN3 RAB26 TPH1	6.23e-05	180	53	4	d553aba594f5304f1c09ff9c6d49b64cd7ee7850
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating-Lymphatic_EC_proliferating_L.2.5.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PARD6G GRIN2B DIAPH3 KIF18B	6.50e-05	182	53	4	f703963b5d1e8c1f95d78807521048553b0792d8
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPY RAP1GAP2 RAB26 TPH1	6.50e-05	182	53	4	0e589bf97d51b4b2f723f8c45853ad81b7ce8778
ToppCell	droplet-Limb_Muscle-nan-21m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM3 COL20A1 GRIN2B DIAPH3	6.50e-05	182	53	4	a512863304fad80acaab60a8c6107eb7c9cbac99
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	TRPM3 COL20A1 HS6ST2 KIF18B	6.50e-05	182	53	4	f7f9be9c7ef8da9864d6aefe20043b26e1bb8697
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PARD6G GRIN2B DIAPH3 KIF18B	6.50e-05	182	53	4	ebd177ad5eac51bf2db0657596618bdf1e5d46e1
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TRPM3 COL20A1 HS6ST2 SOX8	6.64e-05	183	53	4	e0854864d377e158a4793088d1cb6b3dbf2c805d
ToppCell	wk_08-11-Epithelial-PNS-COL20A1+_Schwann\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	TRPM3 COL20A1 HS6ST2 SOX8	6.92e-05	185	53	4	abec2a49fe0f0fa4cba49347207a1ee317333657
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TRPM3 COL20A1 HS6ST2 SOX8	6.92e-05	185	53	4	56c7a0dbf141728ac76b8c90af197719942ca67c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 CCBE1 PARD6G ACTN4	6.92e-05	185	53	4	b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CCNF ACTN1 DIAPH3 KIF18B	7.22e-05	187	53	4	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CCNF ACTN1 DIAPH3 KIF18B	7.22e-05	187	53	4	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HS6ST2 SCRN1 ACTN1 SOX8	7.22e-05	187	53	4	806075c2531a7f5c1da38b85ea494a3b4b5e92ec
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 CCBE1 PARD6G ACTN4	7.22e-05	187	53	4	24c2a3962da364e46e98abeab5f8234376fa26bb
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPY RAP1GAP2 RAB26 TPH1	7.37e-05	188	53	4	b6aad90fa77fbaf80487a55415aa6c245f2d1f7e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 CCBE1 PARD6G ACTN4	7.37e-05	188	53	4	9db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 CCBE1 PARD6G ACTN4	7.37e-05	188	53	4	047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ILDR2 RAP1GAP2 BSN RAB26	7.68e-05	190	53	4	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	(02)_Cycling_Basal_(regeneration)\|World / shred by cell type and Timepoint	CCNF ATRX DIAPH3 KIF18B	7.68e-05	190	53	4	53f017a11ca5ebe9025558e12cedc409cab2e5aa
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	GTF3C1 JMJD6 ACTN4 IFIT2	7.83e-05	191	53	4	04faa7d2237e45418611153294eb6f7bb690cbde
ToppCell	Dividing_Macrophages-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	CCNF ATRX DIAPH3 KIF18B	7.83e-05	191	53	4	3e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCell	(3)_Macrophage_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CCNF ATRX DIAPH3 KIF18B	7.83e-05	191	53	4	b42f0b89bb94fd43786ff50f1caeb3ebfbbb43fd
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAP1GAP2 ACTN3 RAB26 TPH1	7.99e-05	192	53	4	8df4cfe1461819756138ff1180896238dca2787e
ToppCell	droplet-Kidney-nan-3m-Epithelial-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HS6ST2 SCRN1 ACTN1 SOX8	7.99e-05	192	53	4	8b625c22dda23c99654c82c529a1233e99e71b54
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 CCBE1 PARD6G ACTN4	8.15e-05	193	53	4	3eaa0461618582a1754400624350d269d24e750a
ToppCell	(1)_T_cells_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CCNF ATRX DIAPH3 KIF18B	8.32e-05	194	53	4	8f313071933451780309d2174ed27d8cdc734343
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD8-Tem/emra_CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	GTF3C1 RAP1GAP2 PARD6G ACTN4	8.32e-05	194	53	4	ecdfc27d06e363fb23f0309f26ef6404a89f14ec
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CCBE1 ACTN1 SMOC2 CWC25	8.32e-05	194	53	4	90efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CCBE1 ACTN1 SMOC2 CWC25	8.32e-05	194	53	4	df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell	(1)_T_cells-(1)_T_cells_Dividing\|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	CCNF ATRX DIAPH3 KIF18B	8.49e-05	195	53	4	cf00a0b4f341f0487d5b37810abe2952fdd3f6f2
ToppCell	COVID-19-lung-Proliferative_fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	CCNF CCBE1 DIAPH3 KIF18B	8.65e-05	196	53	4	2ce8a787f2731faa913d20342d73041d59468f27
ToppCell	COVID-19-lung-Proliferative_fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CCNF CCBE1 DIAPH3 KIF18B	8.65e-05	196	53	4	ca91d5e325875e7444809b80fcbd491d8899ea36
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX CASP6 ACTN1 SMOC2	8.65e-05	196	53	4	d4df86ce289835e76763213641989fde77935a16
ToppCell	(3)_MNP-(3)_Macrophage_Dividing\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	CCNF ATRX DIAPH3 KIF18B	8.83e-05	197	53	4	048bc4f8fd5d4f394e2384700640f72042336597
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CCNF HS6ST2 DIAPH3 KIF18B	9.00e-05	198	53	4	1fa213e79d828bff6465bde116536dd1b80d94e0
ToppCell	(4)_B_cells-(4)_B_Hypermutation\|(4)_B_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	CCNF ATRX DIAPH3 KIF18B	9.00e-05	198	53	4	8be724a49b4c911d68c3e82fb75e96722d0eaa03
ToppCell	(3)_DC_Monocyte_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CCNF ATRX DIAPH3 KIF18B	9.00e-05	198	53	4	e2b89f6d7c0007ccab62495cd543fe0e5513a9a4
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	ATRX JMJD6 DYNC2I1 SCRN1	9.00e-05	198	53	4	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	cycling_basal_cell\|World / shred by cell class for turbinate	CCNF ATRX DIAPH3 KIF18B	9.00e-05	198	53	4	e86c1224f5b0890a50a25257628e90c790aae7cd
ToppCell	(1)_T_cell_dividing\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	CCNF ATRX DIAPH3 KIF18B	9.00e-05	198	53	4	dac3a16e3a070a37f4d0ea37633c23fdc8a9c70a
ToppCell	(0)_NK_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CCNF ATRX DIAPH3 KIF18B	9.00e-05	198	53	4	5ebb4965b723302152b42bfaf48bb77a57dd02c5
ToppCell	facs-Tongue-nan-3m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYBBP1A ATRX PARD6G ACTN4	9.18e-05	199	53	4	8d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCell	18-Airway-Mesenchymal-Mesenchyme_RSPO2+\|Airway / Age, Tissue, Lineage and Cell class	CCNF CCBE1 DIAPH3 KIF18B	9.18e-05	199	53	4	7ac35e8f45dcdc702422dabd8f3e4d03e2bf61af
ToppCell	(1)_T_cell-(18)_cycling_gd_T\|(1)_T_cell / shred on Cell_type and subtype	CCNF ATRX DIAPH3 KIF18B	9.18e-05	199	53	4	9369d0e4efe809e3e8757294ebebba5a47b30528
ToppCell	(1)_T_cells-(1)_T_cell_dividing\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	CCNF ATRX DIAPH3 KIF18B	9.18e-05	199	53	4	33afdd1b1b951b360ababf440bc556fd9e1c1db2
ToppCell	MS-Multiple_Sclerosis-Lymphocyte-T/NK-T/NK_proliferative\|Multiple_Sclerosis / Disease, condition lineage and cell class	CCNF ILDR2 DIAPH3 KIF18B	9.36e-05	200	53	4	7faf1e37364203a08d2b2544979e848b41e36b1c
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	COL20A1 CCBE1 CHD6 VGLL4	9.36e-05	200	53	4	e16bde12326f0cfc4d03f9307cba0e21ea2389cb
ToppCell	(3)_MNP-(3)_DC_Monocyte_Dividing\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	CCNF ATRX DIAPH3 KIF18B	9.36e-05	200	53	4	d94fe9bd6ee7c1fed14666f24de41bda014e299b
ToppCell	droplet-Heart-HEART-1m-Hematologic-erythrocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 HS6ST2 PSME3	9.82e-05	75	53	3	f1ad409d1b2c5f23bf2b22137e612d627c041b97
ToppCell	(18)_cycling_gd_T\|World / shred on Cell_type and subtype	CCNF ATRX DIAPH3 KIF18B	9.91e-05	203	53	4	7d58929058c4769226a29febee1fd8ba64bc9f1a
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Tuba1c))\|Striatum / BrainAtlas - Mouse McCarroll V32	CCNF CILP2 KIF18B	2.37e-04	101	53	3	0b32e6071f05dbe808e51e18c3a3f8221f438f83
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM3 NATD1 SOX8	4.86e-04	129	53	3	cbeeaa554da971ba2e4c4b82c85a1d070a45abb8
ToppCell	facs-Heart-RV-18m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL1R2 PSME3 FGF16	5.43e-04	134	53	3	d101e16cb87ff72c81324406fe7e3d70ed8f45df
ToppCell	facs-Heart-RV-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL1R2 PSME3 FGF16	5.43e-04	134	53	3	0c63c8b3c748d29c59fcb27d03276ba4f6a0d6b2
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GRIN2B IFIT2 RAB26	6.29e-04	141	53	3	2d2c468783730d81e3cacb0336027ba0ce1e5f4f
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ILDR2 IFIT2 ZNF563	6.29e-04	141	53	3	b5e85f89b930a0ec70cc95733c5ab76ac3e9497f
ToppCell	LPS-antiTNF-Unknown-Endothelial-Monocytes-Macrophages\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL1R2 DIAPH3 IFIT2	6.42e-04	142	53	3	b66f9602dba30d1d4fbcc49ceb112eb5bd916ba1
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	COL20A1 DIAPH3 SOX8	6.96e-04	146	53	3	a317f14a1aab11ffcce65baeb1c475c04324315f
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic_-_developing-DN4_thymocyte\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CCNF KPNA7 KIF18B	7.39e-04	149	53	3	89faa84af68d4727180f39718964bb3bc65d8fe6
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-neutrophil\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL1R2 RAP1GAP2 ACTN1	7.53e-04	150	53	3	6e806a028c0519489151c181d9907e05289e27e0
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	COL20A1 DIAPH3 SOX8	7.53e-04	150	53	3	70ac8ae4b1683fb17278a8e4606f2fa0b94988c0
ToppCell	facs-Heart-LV-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL1R2 PSME3 DIAPH3	7.68e-04	151	53	3	5893a51585a65f1902cf85124a5ed9f02b4eb82a
ToppCell	facs-Heart-LV-18m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL1R2 PSME3 DIAPH3	7.68e-04	151	53	3	771224e0d6fccfa4225b3adccd7bc22a89a40793
ToppCell	Dividing_Macrophages-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	ATRX ZNF221 DIAPH3	7.82e-04	152	53	3	e39cfc346b35235546b303e7d73e4d9d7120a5fb
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial-Progenitor_(NEUROG3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAP1GAP2 ACTN3 RAB26	7.97e-04	153	53	3	20786807bba3bcd70ce744f8b6454e064199ed9f
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PPY IL1R2 SCRN1	8.28e-04	155	53	3	ab539c04f10276ae919d82b1c75f99a84eb695bf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CCNF DIAPH3 KIF18B	8.28e-04	155	53	3	969fc4c98a96bf2f436e8e63d4deb2183ef3b864
Disease	focal segmental glomerulosclerosis 1 (implicated_via_orthology)	ACTN4 ACTN1 ACTN3	5.15e-08	5	52	3	DOID:0111128 (implicated_via_orthology)
Disease	alcohol use disorder (is_implicated_in)	GRIN2B TPH1	3.60e-04	16	52	2	DOID:1574 (is_implicated_in)
Disease	response to selective serotonin reuptake inhibitor	TRPM3 ACTN1 GRIN2B	4.14e-04	82	52	3	EFO_0005658
Disease	Crohn's disease	KPNA7 TRPM3 IL1R2 CHD6 BSN	1.06e-03	441	52	5	EFO_0000384
Disease	preterm premature rupture of the membranes, spontaneous preterm birth	FMNL3 VGLL4	1.12e-03	28	52	2	EFO_0006917, MONDO_0012511

Protein segments in the cluster

Peptide	Gene	Start	Entry
HRPELIDYGKLRKDD	ACTN1	186	P12814
RRHAPGYTRKLSAEE	CWC25	326	Q9NXE8
KLEDFRDYRRVHKPP	ACTN4	331	O43707
RRDKFGRTPLHYAAA	ANKRD52	451	Q8NB46
HRDGMDPDFTYRKRL	DIAPH3	471	Q9NSV4
PRFRLHDYVKREGRG	RAB26	236	Q9ULW5
GLPAHARYVKLEDRD	DSG2	421	Q14126
FSRRSPAKLHELYEK	PNPLA6	941	Q8IY17
APEERRRKFKYRGKD	KPNA7	6	A9QM74
SYGEHPKRRKLLEDY	JMJD6	136	Q6NYC1
RKESLAKDRGGRDYP	BSN	2986	Q9UPA5
FDPAEKYKMDHRRRG	CASP6	31	P55212
LYKEEGERRHRKPRE	DYNC2I1	206	Q8WVS4
VDGTRPRRKKHDYRI	KLHL7	281	Q8IXQ5
PRRKKHDYRIALFGG	KLHL7	286	Q8IXQ5
LADAKGRKTHVPYRD	KIF18B	291	Q86Y91
PDAYRGRGIAKHLAK	NATD1	61	Q8N6N6
RPADRYGLLKHSREF	MYBBP1A	21	Q9BQG0
TRPRYGKRHKEDTLA	PPY	61	P01298
RFSLDRHKPGKFEDF	PARD6G	31	Q9BYG4
SDSEESKKPRYRHRL	ATRX	1326	P46100
PEDRDFRKYGHTSKR	BCLAF3	206	A2AJT9
YRHKRPKLLDGDQDF	BCLAF3	281	A2AJT9
FRYDRPFHKGTKDKE	DOCK4	1416	Q8N1I0
DPGRCLHSFRKLRDY	CCNF	236	P41002
KHRRPYEFEVERDAK	CHD6	2176	Q8TD26
AGKKSLTYFHRDPRA	COL20A1	936	Q9P218
RRQAKEHRPVYEGKD	FMNL3	976	Q8IVF7
DGRRKVHYLFPDGKE	DPCD	21	Q9BVM2
GYRYDRERHRKREKP	CCBE1	116	Q6UXH8
AHRFAQEYKKDPDRG	ADPRS	101	Q9NX46
RSAAKFYRRKDEPDK	IFIT2	251	P09913
GKRDARLRPSRNFHY	HS6ST2	306	Q96MM7
PFTHGKRRYRGKEDA	RER1	176	O15258
DSAQPYKRRGKAHRL	ST13P4	176	Q8IZP2
KGEARAYRRHFLGKD	RAP1GAP2	151	Q684P5
KKEHPGARDGIRYLE	SMG5	896	Q9UPR3
VSRRKAYRLRDGHFK	TADA1	191	Q96BN2
NKDGSPREGYRTKRH	FGF16	166	O43320
YQPRRRKSAKAGHSD	SOX8	171	P57073
RGRHYKREFRLEGEP	IL1R2	31	P27930
RFQEKPDRRHELYKA	SCRN1	336	Q12765
GRPEKDMHGYDIRRF	SARDH	431	Q9UL12
KLEDFRDYRRLHKPP	ACTN3	326	Q08043
RLGYRRTDHDDPAFK	CILP2	841	Q8IUL8
GHILYRPKRATEKFE	CNBD1	121	Q8NA66
EHFRRSLGKNYKEPE	VGLL4	211	Q14135
HDGLDGPTYKKRRLD	PSME3	76	P61289
ADHPGFKDNVYRKRR	TPH1	131	P17752
RGRDLPYHSNSEKKR	ILDR2	606	Q71H61
RAHPAKARDLYKGRQ	SMOC2	286	Q9H3U7
RKHESDPDERDYGLK	TRPM3	1191	Q9HCF6
FQSRGRPHTGKKRYE	ZNF563	156	Q8TA94
GKDYKRRLDLEFHQR	ZNF221	456	Q9UK13
FPGEKSKRLRYHDEA	GTF3C1	1236	Q12789
SPDHKRYFRDKEGLR	GRIN2B	1116	Q13224