Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphatidylinositol-3,4-bisphosphate 4-phosphatase activity

INPP4A INPP4B

1.02e-0422022GO:0016316
GeneOntologyMolecularFunctioninositol-3,4-bisphosphate 4-phosphatase activity

INPP4A INPP4B

1.02e-0422022GO:0052828
GeneOntologyMolecularFunctioninositol-1,3,4-trisphosphate 4-phosphatase activity

INPP4A INPP4B

1.02e-0422022GO:0017161
GeneOntologyCellularComponentGolgi-associated vesicle

CLTCL1 LRRK2 CLTC ZDHHC13 GOPC ZDHHC17 IGF2R

1.18e-041142017GO:0005798
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE2 SYNE1 SUN3

1.37e-04112013GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE2 SYNE1 SUN3

1.37e-04112013GO:0106094
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE2 SYNE1 SUN3

1.37e-04112013GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE2 SYNE1 SUN3

1.37e-04112013GO:0034993
GeneOntologyCellularComponentGolgi-associated vesicle membrane

CLTCL1 CLTC ZDHHC13 GOPC ZDHHC17

3.01e-04612015GO:0030660
GeneOntologyCellularComponenttrans-Golgi network transport vesicle

CLTCL1 CLTC GOPC IGF2R

5.78e-04402014GO:0030140
DomainSpectrin

SPTB ACTN1 SYNE2 DRP2 SYNE1

3.95e-06232015PF00435
DomainACTININ_2

SPTB ACTN1 SYNE2 SYNE1 LCP1

3.95e-06232015PS00020
DomainACTININ_1

SPTB ACTN1 SYNE2 SYNE1 LCP1

3.95e-06232015PS00019
DomainActinin_actin-bd_CS

SPTB ACTN1 SYNE2 SYNE1 LCP1

3.95e-06232015IPR001589
DomainSpectrin_repeat

SPTB ACTN1 SYNE2 DRP2 SYNE1

1.32e-05292015IPR002017
DomainSPEC

SPTB ACTN1 SYNE2 DRP2 SYNE1

2.18e-05322015SM00150
DomainSpectrin/alpha-actinin

SPTB ACTN1 SYNE2 DRP2 SYNE1

2.18e-05322015IPR018159
DomainRasGAP_dom

PLXNB2 NF1 RASA4B RASA4

3.54e-05182014IPR001936
DomainClathrin_H-chain_propeller_rpt

CLTCL1 CLTC

1.15e-0422012IPR022365
DomainClathrin-link

CLTCL1 CLTC

1.15e-0422012PF09268
Domain-

CLTCL1 CLTC

1.15e-04220122.130.10.110
DomainClathrin_heavy_chain

CLTCL1 CLTC

1.15e-0422012IPR016341
DomainClathrin_H-chain_propeller_N

CLTCL1 CLTC

1.15e-0422012IPR001473
DomainClathrin_H-chain_link/propller

CLTCL1 CLTC

1.15e-0422012IPR016025
DomainClathrin_propel

CLTCL1 CLTC

1.15e-0422012PF01394
DomainClathrin_H-chain_linker_core

CLTCL1 CLTC

1.15e-0422012IPR015348
DomainARM-type_fold

CLTCL1 LRRK2 MROH5 ARMC2 LYST NCAPG2 ITPR1 DNAAF5 NF1 PIK3CB CLTC UBR4

3.20e-0433920112IPR016024
DomainLRR

LRRK2 DNAL1 SLITRK2 PPP1R37 LRRIQ3 LGR5 TLR10 TLR1 SLITRK5

3.37e-042012019PS51450
DomainClathrin_H-chain_linker

CLTCL1 CLTC

3.43e-0432012IPR012331
Domain-

RASA4B RASA4

3.43e-04320124.10.1130.10
DomainCLH

CLTCL1 CLTC

3.43e-0432012SM00299
DomainRho_GTPase_activation_prot

PLXNB2 NF1 RASA4B DEPDC1 ARHGAP5 RASA4

3.76e-04882016IPR008936
DomainRasGAP

NF1 RASA4B RASA4

4.10e-04142013SM00323
DomainRasGAP_CS

NF1 RASA4B RASA4

4.10e-04142013IPR023152
DomainRasGAP

NF1 RASA4B RASA4

5.08e-04152013PF00616
DomainRAS_GTPASE_ACTIV_1

NF1 RASA4B RASA4

5.08e-04152013PS00509
DomainRAS_GTPASE_ACTIV_2

NF1 RASA4B RASA4

5.08e-04152013PS50018
DomainAnkyrin_rpt

RTP1 LRRK2 ANKRD28 ZDHHC13 ANKRD52 ASB14 ZDHHC17 PPP1R16B TNKS2 INVS

5.64e-0426220110IPR002110
Domain-

PLXNB2 RASA4B RASA4

6.20e-041620131.10.506.10
DomainCH

SPTB ACTN1 SYNE2 SYNE1 LCP1

6.72e-04652015SM00033
DomainKASH

SYNE2 SYNE1

6.82e-0442012IPR012315
DomainKASH

SYNE2 SYNE1

6.82e-0442012PS51049
DomainKASH

SYNE2 SYNE1

6.82e-0442012SM01249
DomainKASH

SYNE2 SYNE1

6.82e-0442012PF10541
DomainCH

SPTB ACTN1 SYNE2 SYNE1 LCP1

9.43e-04702015PF00307
Domain-

SPTB ACTN1 SYNE2 SYNE1 LCP1

1.01e-037120151.10.418.10
Domain-

INPP4A INPP4B PIK3CB RASA4B SMURF2 CAPN6 RASA4

1.12e-0314820172.60.40.150
DomainGAE

GGA3 GGA1

1.13e-0352012PS50180
DomainToll-like_receptor

TLR10 TLR1

1.13e-0352012IPR017241
DomainCH

SPTB ACTN1 SYNE2 SYNE1 LCP1

1.14e-03732015PS50021
DomainCH-domain

SPTB ACTN1 SYNE2 SYNE1 LCP1

1.29e-03752015IPR001715
Domain-

LRRK2 ANKRD28 ZDHHC13 ANKRD52 ASB14 ZDHHC17 PPP1R16B TNKS2 INVS

1.50e-0324820191.25.40.20
Domain-

GGA3 GGA1

1.68e-03620122.60.40.1230
DomainGAT_dom

GGA3 GGA1

1.68e-0362012IPR004152
Domain-

GGA3 GGA1

1.68e-03620121.20.58.160
DomainClathrin_g-adaptin_app

GGA3 GGA1

1.68e-0362012IPR008153
DomainGAT

GGA3 GGA1

1.68e-0362012PS50909
DomainGAT

GGA3 GGA1

1.68e-0362012PF03127
DomainAnkyrin_rpt-contain_dom

LRRK2 ANKRD28 ZDHHC13 ANKRD52 ASB14 ZDHHC17 PPP1R16B TNKS2 INVS

1.77e-032542019IPR020683
Pubmed

Defining the membrane proteome of NK cells.

ABCF1 CLTCL1 MYCBP2 AGPAT3 PRPF6 TTK MELK NCAPG2 ITPR1 NF1 MDN1 PNPLA6 EIF3L CLTC FEN1 ZDHHC13 DIP2B PSMF1 UBR4 RNF213 CERS6 IGF2R LNPEP GNA13 SERPINB1 OGA GGA1 RPL3L CNOT1

6.98e-1111682052919946888
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ABCF1 MYCBP2 DNAJC21 NBN PRPF6 PLXNB2 TTK NCAPG2 ITPR1 DAP3 PTPN13 MDN1 PNPLA6 SYNE2 CLTC ANKRD28 ANKRD52 STIM2 PDPR GOPC SYNE1 UBR4 SPG11 ZDHHC17 IGF2R LNPEP CTR9 PPA2 POLDIP2 OGA

4.22e-0914872053033957083
Pubmed

Functional proteomics mapping of a human signaling pathway.

MYCBP2 INPP4A GGA3 EIF3L PPP1R37 ANKRD28 ZNF107 SMURF2 TTF2 STIM2 UBR4 ARHGAP5 ZNF41 LNPEP CTR9 TNKS2 GGA1 INVS

1.69e-085912051815231748
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

ABCF1 MYO5B MYCBP2 AGPAT3 CDH23 TSG101 GOLPH3 PRPF6 ACTN1 MELK NCAPG2 TULP3 DNAAF5 PTPN13 NF1 EIF3L ANKRD28 LCA5 CNOT11 GOPC RADX FANCL USP46 CTR9 GGA1 CNOT1 INVS

2.09e-0813212052727173435
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

MBTPS1 ABCF1 MYCBP2 DCBLD1 TSG101 EXT1 PLXNB2 NCAPG2 ITPR1 GGH NF1 PTPRS TXNDC16 ZDHHC13 POMT2 STIM2 GOPC RNF213 CERS6 KLHL11 IGF2R PRCP LNPEP SLITRK5 LRP6

5.16e-0812012052535696571
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MYO5B MYCBP2 NBN TULP3 ITPR1 PTPN13 PTPRS SSH3 SYNE2 CLTC PPP1R37 ANKRD28 ANKRD52 PDPR GOPC RNF213 USP46 ARHGAP5 IGF2R LNPEP CTR9 LRP6 CNOT1

7.32e-0810492052327880917
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

ABCF1 PRPF6 RAD54L2 SRCAP MDN1 CLTC DIP2B UBR4 RNF213 SRRT MTA1 CTR9 MDC1

1.03e-073322051332786267
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

NCAPG2 ITPR1 PTPN13 NF1 MDN1 PNPLA6 RADX RNF213

2.02e-07104205831240132
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PHYKPL MBTPS1 CDH26 PDE4D MYCBP2 INPP4A SPTB AGPAT3 ARMC2 DNAH14 TULP3 DNAAF5 PTPN13 PNPLA6 PTPRS ZNF107 ZDHHC13 SMURF2 PRUNE2 DIP2B PSMF1 RNF213 CERS6 JMJD1C MSRA CNOT1 INVS

2.32e-0714892052728611215
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

PDE4D MYCBP2 EXT1 TULP3 SYNE2 PITPNA TBX3 SATB2 CNOT11 MSRA SRRT MDC1 CNOT1

2.45e-073582051332460013
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ABCF1 MYCBP2 PRPF6 ACTN1 NF1 MDN1 SYNE2 EIF3L CLTC ANKRD28 ANKRD52 USP47 UBR4 LCP1 IGF2R MDC1 CNOT1

3.94e-076532051722586326
Pubmed

Autoinhibition of the ligand-binding site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif.

GGA3 IGF2R GGA1

8.04e-074205312060753
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

ADAMTS19 ERCC2 CLTCL1 GPBP1 MYCBP2 SPTB LRRK2 PLXNB2 DNAH14 ITPR1 NF1 PTPRS FEN1 ANKRD28 SMURF2 FAM76B CPS1 CYRIB TADA1 ZNF100 PPA2 RRN3P1 C1orf94

9.49e-0712152052315146197
Pubmed

Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes.

ALDH1L1 FEN1 CPS1 FADS3

1.12e-0614205423378610
Pubmed

The GGAs promote ARF-dependent recruitment of clathrin to the TGN.

GGA3 CLTC GGA1

2.00e-065205311301005
Pubmed

Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins.

GGA3 IGF2R GGA1

2.00e-065205314567678
Pubmed

Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains.

GGA3 IGF2R GGA1

2.00e-065205311859375
Pubmed

Clathrin terminal domain-ligand interactions regulate sorting of mannose 6-phosphate receptors mediated by AP-1 and GGA adaptors.

GGA3 CLTC GGA1

2.00e-065205324407285
Pubmed

Sorting of mannose 6-phosphate receptors mediated by the GGAs.

GGA3 IGF2R GGA1

2.00e-065205311387475
Pubmed

GGA2 interacts with EGFR cytoplasmic domain to stabilize the receptor expression and promote cell growth.

GGA3 IGF2R GGA1

2.00e-065205329358589
Pubmed

GGA and Arf proteins modulate retrovirus assembly and release.

TSG101 GGA3 GGA1

2.00e-065205318439901
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

ABCF1 GPBP1 MYCBP2 PRPF6 SRCAP MAP3K4 ITPR1 NF1 CLTC MED23 SRRT CTR9 MDC1

2.44e-064402051334244565
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

MBTPS1 CLTCL1 IRF3 TSG101 PRPF6 MELK INPP4B NF1 MDN1 FEN1 SMURF2 USP46 XPNPEP2 CPS1 TLR10 THRSP CTR9 LRP6 ZNF85 GGA1 TM4SF20 ANO3 INVS

2.69e-0612932052315342556
Pubmed

Interactions of GGA3 with the ubiquitin sorting machinery.

TSG101 GGA3 GGA1

3.98e-066205315039775
Pubmed

Human transcription factor protein interaction networks.

NBN IRF3 RAD54L2 SRCAP DAP3 SYNE2 EIF3L ANKRD28 ZNF107 QKI SATB2 CNOT11 RADX UBR4 USP46 JMJD1C SRRT TADA1 MTA1 MDC1 LRP6 ZMYM1 POLDIP2 CNOT1

4.29e-0614292052435140242
Pubmed

Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domains.

GGA3 IGF2R GGA1

6.94e-067205311390366
Pubmed

Regulation of cargo transfer between ESCRT-0 and ESCRT-I complexes by flotillin-1 during endosomal sorting of ubiquitinated cargo.

TSG101 GGA3 CLTC

6.94e-067205328581508
Pubmed

Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases.

SLITRK2 PTPRS SLITRK5

6.94e-067205323345436
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ABCF1 MYCBP2 SPTB TSG101 ACTN1 RAD54L2 PTPN13 CLTC QKI SMURF2 USP47 SETMAR SYNE1 TAF1C UBR4 CAMK1 ARHGAP5 MTA1 CTR9 PPP1R16B POLDIP2 TNKS2

8.21e-0612852052235914814
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

ERCC2 MYCBP2 TSG101 PLXNB2 TTK MELK GGH DNAAF5 SYNE2 EIF3L CLTC GOPC UBR4 IGF2R FADS3 PRCP LNPEP GNA13 MDC1 PPA2 SERPINB1 CNOT1

9.49e-0612972052233545068
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ERCC2 PDE4A CLTCL1 MYCBP2 SRCAP PLXNB2 LYST GGA3 MDN1 PNPLA6 PTPRS SMURF2 CREB3 KHNYN UBR4 ICE1 IGF2R PPA2 PCNX1 GGA1

9.75e-0611052052035748872
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ERCC2 NBN TSG101 SRCAP ACY1 PLEKHN1 DAP3 PNPLA6 ANKRD28 ZDHHC13 ANKRD52 TBX3 GOPC TAF1C RNF213 PRDM5 TADA1 MTA1 IL21R POLDIP2

1.13e-0511162052031753913
Pubmed

Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs.

TSG101 GGA3 CLTC IGF2R

1.14e-0524205437100772
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ABCF1 MYCBP2 PRPF6 ACTN1 SRCAP MELK NCAPG2 NF1 MDN1 PNPLA6 EIF3L CLTC FEN1 PPP1R37 ANKRD28 ANKRD52 TTF2 TAF1C UBR4 SRRT CTR9 MDC1

1.82e-0513532052229467282
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

ERCC2 ABCF1 PRPF6 NCAPG2 MAP3K4 DAP3 EIF3L CLTC FEN1 TTF2 HSD17B7 PDPR UBR4 CPS1 CNOT1

2.10e-057042051529955894
Pubmed

The trihelical bundle subdomain of the GGA proteins interacts with multiple partners through overlapping but distinct sites.

TSG101 GGA3 GGA1

2.35e-0510205315143060
Pubmed

Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.

AGPAT3 FEN1 STIM2 FADS3

2.48e-0529205421829377
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

CLTCL1 ABCA13 LYST ADAM28 ITPR1 RNF213 GRIK3 XPNPEP2 ASB14 LCP1 DCLRE1C PRCP ZNF554

2.72e-055522051310737800
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

MYCBP2 PRPF6 MELK EIF3L ANKRD28 QKI ANKRD52 USP47 TAF1C ICE1 USP46 TADA1 IGF2R GNA13 NUDCD1 OGA RPL3L CNOT1

3.17e-0510052051819615732
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

ABCF1 MYCBP2 PRPF6 ACTN1 RAD54L2 NCAPG2 CLTC FEN1 MED23 QKI TTF2 SATB2 GOPC FAM76B LCP1 JMJD1C MTA1 CTR9 CNOT1

3.22e-0511032051934189442
Pubmed

Toll-like receptor 1 and 10 polymorphisms, Helicobacter pylori susceptibility and risk of gastric lesions in a high-risk Chinese population.

TLR10 TLR1

3.46e-052205225687912
Pubmed

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

SYNE2 SYNE1

3.46e-052205211792814
Pubmed

CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.

RASA4B RASA4

3.46e-052205211448776
Pubmed

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.

SYNE2 SYNE1

3.46e-052205224931616
Pubmed

Srcap haploinsufficiency induced autistic-like behaviors in mice through disruption of Satb2 expression.

SRCAP SATB2

3.46e-052205238733588
Pubmed

The isolation and characterization of cDNA encoding human and rat brain inositol polyphosphate 4-phosphatase.

INPP4A INPP4B

3.46e-05220527608176
Pubmed

Altered Expression of EPO Might Underlie Hepatic Hemangiomas in LRRK2 Knockout Mice.

EPO LRRK2

3.46e-052205227872856
Pubmed

The cDNA cloning and characterization of inositol polyphosphate 4-phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family.

INPP4A INPP4B

3.46e-05220529295334
Pubmed

Dysregulated striatal neuronal processing and impaired motor behavior in mice lacking huntingtin interacting protein 14 (HIP14).

ZDHHC13 ZDHHC17

3.46e-052205224376823
Pubmed

Epistasis between IGF2R and ADAMTS19 polymorphisms associates with premature ovarian failure.

ADAMTS19 IGF2R

3.46e-052205224014609
Pubmed

A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage.

NBN MDC1

3.46e-052205219804756
Pubmed

Functional communication between IP3R and STIM2 at subthreshold stimuli is a critical checkpoint for initiation of SOCE.

ITPR1 STIM2

3.46e-052205235022238
Pubmed

Toll-like receptor 1 and 10 gene polymorphisms are linked to postbronchiolitis asthma in adolescence.

TLR10 TLR1

3.46e-052205228692144
Pubmed

Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in 3T3-F442A preadipocytes.

PDE4A PDE4D

3.46e-05220529520403
Pubmed

Genetic polymorphisms in TLR1, TLR2, TLR4, and TLR10 of Helicobacter pylori-associated gastritis: a prospective cross-sectional study in Thailand.

TLR10 TLR1

3.46e-052205228368946
Pubmed

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

SYNE2 SYNE1

3.46e-052205222768332
Pubmed

Characterization of a second human clathrin heavy chain polypeptide gene (CLH-22) from chromosome 22q11.

CLTCL1 CLTC

3.46e-05220528733129
Pubmed

Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport.

ZDHHC13 ZDHHC17

3.46e-052205218794299
Pubmed

Altered Regulation of Striatal Neuronal N-Methyl-D-Aspartate Receptor Trafficking by Palmitoylation in Huntington Disease Mouse Model.

ZDHHC13 ZDHHC17

3.46e-052205230846936
Pubmed

CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.

CLTCL1 CLTC

3.46e-052205229097553
Pubmed

Phosphoregulation of sorting signal-VHS domain interactions by a direct electrostatic mechanism.

GGA3 IGF2R

3.46e-052205212032548
Pubmed

Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.

SYNE2 SYNE1

3.46e-052205217267447
Pubmed

Nesprins: tissue-specific expression of epsilon and other short isoforms.

SYNE2 SYNE1

3.46e-052205224718612
Pubmed

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

SYNE2 SYNE1

3.46e-052205224586179
Pubmed

Polymorphisms at Locus 4p14 of Toll-Like Receptors TLR-1 and TLR-10 Confer Susceptibility to Gastric Carcinoma in Helicobacter pylori Infection.

TLR10 TLR1

3.46e-052205226559190
Pubmed

SYNE1-QK1 SNPs, G × G and G × E interactions on the risk of hyperlipidaemia.

QKI SYNE1

3.46e-052205232281752
Pubmed

The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step.

CLTCL1 CLTC

3.46e-052205220065094
Pubmed

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

SYNE2 SYNE1

3.46e-052205217761684
Pubmed

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.

SYNE2 SYNE1

3.46e-052205231578382
Pubmed

Toll-like receptor 1 and 10 variations increase asthma risk and review highlights further research directions.

TLR10 TLR1

3.46e-052205230924193
Pubmed

Structure of a second BRCT domain identified in the nijmegen breakage syndrome protein Nbs1 and its function in an MDC1-dependent localization of Nbs1 to DNA damage sites.

NBN MDC1

3.46e-052205218582474
Pubmed

Protective LRRK2 R1398H Variant Enhances GTPase and Wnt Signaling Activity.

LRRK2 LRP6

3.46e-052205227013965
Pubmed

An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.

RASA4B RASA4

3.46e-052205216041389
Pubmed

Hip14l-deficient mice develop neuropathological and behavioural features of Huntington disease.

ZDHHC13 ZDHHC17

3.46e-052205223077216
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

ABCF1 DNAJC21 RAD54L2 NCAPG2 ITPR1 ANKRD28 DIP2B TBX3 ZDHHC17 JMJD1C KLHL11 SRRT CTR9 POLDIP2

3.54e-056502051438777146
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

MYO5B LRRK2 IRF6 TSG101 ACTN1 ALDH1L1 ACY1 GGH PTPN13 CLTC XPNPEP2 LCP1 PKD1L3 CYRIB MSRA IGF2R PRCP SERPINB1

3.65e-0510162051819056867
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

SRCAP PLXNB2 MDN1 ANKRD28 PRUNE2 KHNYN

3.66e-0510420569205841
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

DCBLD1 PLEKHN1 TULP3 SLITRK2 NF1 NRK PPP1R37 ZDHHC13 DIP2B STIM2 GOPC IGF2R LNPEP

3.71e-055692051330639242
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

MBTPS1 PLXNB2 TTK ACSBG1 PIK3CB SYNE2 PITPNA EIF3L FEN1 LRP5L ZNF282 TAF1C UBR4 ICE1 JMJD1C CYRIB PRKAB1 POLDIP2 OGA

4.15e-0511242051921900206
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

MBTPS1 INPP4A EXT1 HSD11B1L TTK NCAPG2 NF1 PIK3CB CLTC CNOT11 PSMF1 HSD17B7 UBR4 SPG11 TADA1 CTR9 GNA13 PRKAB1 MTBP OGA CNOT1

4.20e-0513272052132694731
Pubmed

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.

ERCC2 NBN SRCAP FEN1 MTA1 DCLRE1C MDC1

4.31e-05157205730686591
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CLTCL1 MYO5B DNAJC21 PRPF6 ACTN1 RAD54L2 SRCAP LYST DAP3 MDN1 SYNE2 CLTC SMURF2 STIM2 SYNE1 UBR4 SPG11 ZDHHC17 LCP1 CTR9 GNA13 RPL3L

4.72e-0514422052235575683
Pubmed

A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.

GPBP1 ACTN1 HSD11B1L PLXNB2 ITPR1 CLTC MED23 CREB3 LCA5 UBR4 IGF2R CTR9

4.91e-055032051236217030
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

AGPAT3 EXT1 PRPF6 PLXNB2 ITPR1 GGH CLTC POMT2 STIM2 HSD17B7 PDPR GOPC RNF213 USP46 ZDHHC17 NMNAT3 SRRT IGF2R FADS3 LNPEP PPA2 POLDIP2

5.17e-0514512052230550785
Pubmed

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.

ACTN1 DIP2B CPS1 JMJD1C

5.32e-0535205423969696
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

GGA3 PPP1R37 PRUNE2 GOPC USP46 IGF2R LNPEP SLITRK5 GGA1

5.35e-05285205934369648
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

TSG101 RAD54L2 KDM5D TULP3 GGA3 CLTC PRUNE2 UBR4 MTA1 MDC1 ZMYM1

5.46e-054302051135044719
Pubmed

Genetic interaction mapping in mammalian cells using CRISPR interference.

SRCAP MED23 MTA1 CTR9 CNOT1

5.61e-0569205528481362
Pubmed

Polymorphisms in DNA repair and one-carbon metabolism genes and overall survival in diffuse large B-cell lymphoma and follicular lymphoma.

ERCC2 NBN ALDH1L1 GGH

5.96e-0536205418830263
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

MYCBP2 SYNE2 ANKRD28 PRUNE2 SYNE1 PPP1R16B PCNX1 OGA

6.13e-05225205812168954
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ABCF1 MYCBP2 NBN NF1 MDN1 PNPLA6 CLTC USP47 DIP2B FAM76B SRRT MTA1 CTR9 MDC1 OGA

6.17e-057742051515302935
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

MYCBP2 ABCA13 CDH23 NF1 UBR4 ICE1 JMJD1C MDC1 MTBP C1orf94

6.20e-053612051026167880
Pubmed

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.

CLTCL1 DAP3 MDN1 CLTC USP47 CNOT11 GOPC CNOT1

6.32e-05226205825900982
Pubmed

Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.

DCBLD1 TBX3 GOPC

7.00e-0514205323266556
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MELK GGA3 ACSBG1 MED23 SATB2 PDPR SPG11 ICE1 MDC1 PCNX1 OGA CNOT1

7.93e-055292051214621295
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

MYCBP2 PLXNB2 TTK ITPR1 DAP3 MDN1 SYNE2 CLTC QKI USP47 DIP2B TTF2 PDSS2 STIM2 PDPR GOPC SYNE1 UBR4 RNF213 ZDHHC17 PPA2 POLDIP2

8.06e-0514962052232877691
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

ABCF1 MYCBP2 TSG101 PRPF6 SRCAP GGH DAP3 PTPN13 CLTC FEN1 MED23 DIP2B SYNE1 FAM76B ZCCHC4 SRRT POLDIP2 CNOT1

8.14e-0510822051838697112
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

ABCF1 ACTN1 NCAPG2 DNAAF5 SSH3 EIF3L ZNF107 CPS1 SRRT ZNF100 ZSCAN22

8.35e-054512051136168627
Pubmed

AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair.

NBN GOLPH3 ANKRD28 ANKRD52 DCLRE1C PRKAB1

8.53e-05121205631900314
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

NBN RAD54L2 NCAPG2 MDN1 MAD2L2 FANCL ICE1 JMJD1C SRRT TADA1 MDC1

8.68e-054532051129656893
InteractionC19orf38 interactions

NCAPG2 DNAAF5 NF1 PRMT9 MAD2L2 RNF213 DEPDC1 CAMK1

2.50e-06862038int:C19orf38
InteractionPRKY interactions

CLTCL1 NBN RAD54L2 MELK PTPN13 TTF2 SPG11 CAMK1 OGA

1.26e-051402039int:PRKY
Cytoband6q26

MAP3K4 QKI IGF2R

6.81e-051820536q26
Cytoband11p15.3

USP47 CTR9 STK33

1.10e-0421205311p15.3
CytobandXq22.3

NRK AMMECR1 RADX

4.34e-04332053Xq22.3
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

INPP4A INPP4B SMURF2 CAPN6

1.22e-04361294823
GeneFamilyGolgi associated, gamma adaptin ear containing, ARF binding proteins

GGA3 GGA1

1.51e-04312921031
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE2 SYNE1

3.00e-04412921252
GeneFamilyAnkyrin repeat domain containing

ANKRD28 ZDHHC13 ANKRD52 ASB14 ZDHHC17 PPP1R16B TNKS2 INVS

3.48e-042421298403
GeneFamilyProtein phosphatase 6 regulatory subunits

ANKRD28 ANKRD52

7.44e-0461292699
GeneFamilyZinc fingers GRF-type|Topoisomerases

TTF2 ZCCHC4

1.04e-0371292135
GeneFamilyCD molecules|Toll like receptors

TLR10 TLR1

2.19e-03101292948
GeneFamilyPatatin like phospholipase domain containing

PNPLA1 PNPLA6

2.19e-03101292466
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

RASA4B RASA4

2.19e-03101292830
GeneFamilyCCR4-NOT transcription complex

CNOT11 CNOT1

2.66e-031112921023
GeneFamilyATP binding cassette subfamily A

ABCA13 ABCA10

4.35e-03141292805
CoexpressionGSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP

AGBL5 TTK MELK NCAPG2 SYNE2 FANCL DEPDC1 KYAT1 DCLRE1C PCNX1 ZMYM1

3.85e-0719420411M7467
CoexpressionGSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_UP

AGPAT3 IRF6 ACTN1 MAP3K4 TXNDC16 ZNF282 SYNE1 PRDM5 ZCCHC4 IGF2R

4.08e-0620020410M7148
CoexpressionGSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN

PLXNB2 MELK NCAPG2 FEN1 FANCL DEPDC1 CAMK1 FADS3 LNPEP MDC1

4.08e-0620020410M3188
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

GPBP1 MYCBP2 NBN EXT1 TTK ITPR1 GGH PTPN13 SYNE2 ZNF107 USP47 SPG11 DEPDC1 ARHGAP5 DCLRE1C ZMYM1 ZNF85

1.64e-0565620417M18979
CoexpressionGSE40685_NAIVE_CD4_TCELL_VS_TREG_UP

SRCAP MAP3K4 EIF3L AMMECR1 LCA5 XPNPEP2 PRDM5 TADA1 PPP1R16B

2.65e-051982049M9305
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE4D INPP4B MAP3K4 PTPN13 SYNE2 NMNAT3 PPP1R16B PCNX1 OGA

8.18e-08167204983969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

MYCBP2 MAP3K4 CLTC ZNF107 TTF2 RNF213 FANCL RASA4 INVS

1.96e-071852049a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

MYCBP2 MAP3K4 CLTC ZNF107 TTF2 RNF213 FANCL RASA4 INVS

2.05e-0718620498571956890fc9894d766ba294a28e376b4aba428
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 LRRK2 ADARB2 DNAH14 NRK SYNE2 PRUNE2 SATB2 SYNE1

2.05e-071862049f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

GPBP1 ITPR1 NF1 SYNE2 RNF213 JMJD1C IGF2R LNPEP PCNX1

2.24e-071882049ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

CLTC AMMECR1 MED23 DIP2B KLHL11 IGF2R CTR9 UHMK1 PCNX1

2.80e-071932049abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

INPP4A SRCAP SYNE2 SYNE1 DDX60 RNF213 LCP1 IGF2R LNPEP

3.78e-0720020492281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INPP4B PTPN13 ACSBG1 AMMECR1 TTF2 SETMAR PDPR DEPDC1

1.11e-061682048a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5B AGPAT3 ACTN1 KDM5D GGA3 TAF1C ZSCAN22 CTR9

1.27e-061712048d1e87478d8c0329e662849823f5c7604f20e1b1a
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 LRRK2 PIK3CB SYNE2 SATB2 SYNE1 DDX60 PCNX1

1.51e-061752048cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INPP4A MAP3K4 ACSBG1 GRIK3 KYAT1 MDC1 TLR1 UHMK1

1.72e-061782048f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCellCOVID-19-APC-like-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

ADAM28 STIM2 CD207 LCP1 CYRIB TLR10 IL21R TLR1

2.11e-061832048703364836b42aa6ac6c68b42b700ac23c4a1afc7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 SLITRK2 NRK DRP2 GRIK3 CPS1 HMCN1 ANO3

2.20e-0618420482cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 SLITRK2 NRK DRP2 GRIK3 CPS1 HMCN1 ANO3

2.20e-0618420482b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 SLITRK2 NRK DRP2 GRIK3 CPS1 HMCN1 ANO3

2.20e-061842048ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRF6 LYST NRK SYNE2 ARHGAP5 HMCN1 TIE1 PPP1R16B

2.38e-0618620480ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 LRRK2 ADARB2 DNAH14 NRK SYNE2 PRUNE2 SATB2

2.48e-061872048c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 LRRK2 ADARB2 DNAH14 SYNE2 PRUNE2 SATB2 STK33

2.58e-061882048af740fa78542438fdff627ea1f74f4eee43316be
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLTC QKI DIP2B LCP1 JMJD1C CYRIB ARHGAP5 TNKS2

2.68e-0618920486dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCell3'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE4D ACTN1 PRUNE2 ARHGEF25 AOC3 SLITRK5 FAM124A ANO3

2.68e-06189204863449d9f1e78ff2bc8786eb88a0d177fe30c7f4d
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLTC QKI DIP2B LCP1 JMJD1C CYRIB ARHGAP5 TNKS2

2.68e-061892048875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLTC QKI DIP2B LCP1 JMJD1C CYRIB ARHGAP5 TNKS2

2.68e-0618920483ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCellfacs-Brain_Myeloid-Striatum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLTC QKI DIP2B LCP1 JMJD1C CYRIB ARHGAP5 TNKS2

2.68e-06189204897ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCellControl-cDC-|Control / Disease condition and Cell class

ADAM28 ANKRD28 PRMT9 TLR10 ARHGAP5 PRCP PPA2 JHY

3.38e-061952048a2b4d9473eff73f088b247ce43e66f013622471e
ToppCellControl-cDC|Control / Disease condition and Cell class

ADAM28 ANKRD28 PRMT9 TLR10 ARHGAP5 PRCP PPA2 JHY

3.38e-061952048b96acdd22dd3885af69328f170ea871a0d570034
ToppCellBL|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LRRK2 NBN LYST RNF213 LCP1 CYRIB IGF2R PCNX1

3.65e-0619720481acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

MYO5B LRRK2 PLXNB2 ADAM28 PTPN13 SYNE2 SETMAR FADS3

3.65e-0619720486b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCellControl-Control-Lymphocyte-T/NK-NK_activated|Control / Disease, condition lineage and cell class

INPP4A SYNE2 POMT2 SYNE1 DDX60 RNF213 LCP1 LNPEP

3.79e-06198204876d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCellLPS_only-Hematopoietic_Myeloid-Dendritic_cells-mDC|LPS_only / Treatment groups by lineage, cell group, cell type

PDE4A CERS6 LCP1 PKD1L3 CYRIB TLR10 IL21R TLR1

3.79e-06198204853c22e81e530d6fc272d4a45c8d1bf125feb254d
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

TTK MELK NCAPG2 GGH SYNE2 FEN1 SYNE1 DEPDC1

3.93e-061992048101f78fe6dd1bf9e2e4dd5ad8a970312b3540927
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TTK MELK NCAPG2 GGH SYNE2 FEN1 SYNE1 DEPDC1

3.93e-061992048e0fcec796afe75e42467ca86355b9fc5aa9ae0a1
ToppCellLPS_IL1RA|World / Treatment groups by lineage, cell group, cell type

ABCF1 DNAJC21 NBN NF1 SYNE2 SMURF2 CREB3 SERPINB1

4.08e-062002048a02fa5b3c4723a6eaa3c685588666c710478dd25
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ERCC2 CDH26 ABCA13 SPTB MDM1 GGA3 SSH3

1.27e-0516820478f0c4dfad9f6fed9dcc31795abfe77758ceb46a1
ToppCellNS-critical-d_0-4-Lymphoid-B_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FSIP2 TXNDC16 PRMT9 TAF1C MTA1 FADS3 MDC1

1.42e-051712047bd1ebd9037a740ad8c01c460d778b0973d8b56df
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLTC PRUNE2 RNF213 LCP1 DCLRE1C RASA4 IL21R

1.48e-051722047c96bd3407911df3e3e6d7a3dba786b11814b9598
ToppCelldroplet-Marrow-nan-3m-Hematologic-proerythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRK2 ACTN1 LYST ITIH3 SYNE1 DDX60 LCP1

1.48e-051722047cfcfa7eeff1805bedf10a3c07826459914c3e872
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 LRRK2 ACTN1 LYST PIK3CB SYNE1 DDX60

1.48e-051722047d354424c1f861b6607dfd63b9724f4c237b30275
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLEKHN1 TTK MELK NCAPG2 NF1 TTF2 DEPDC1

1.59e-051742047c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLEKHN1 TTK MELK NCAPG2 NF1 TTF2 DEPDC1

1.59e-05174204772df66319f6efbd88ecf439013d97409fbf3cb52
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLTC PRUNE2 LCP1 DCLRE1C RASA4 IL21R TLR1

1.65e-051752047d983e80eeb11f341c564ea684e2b0b585a90ae58
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPBP1 PRPF6 LYST JMJD1C ARHGAP5 HMCN1 LNPEP

1.71e-051762047749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLTC PRUNE2 LCP1 DCLRE1C RASA4 IL21R TLR1

1.91e-051792047fae869fb0a91428481bf8a9c111dcc639e2b4278
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DNAL1 KDM5D ACY1 TTK MELK ANKRD52 DEPDC1

1.91e-051792047021d782134126c6f7dce6b6ea50cc54bdaa39987
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERCC2 INPP4B PTPN13 ACSBG1 RADX ZCCHC4 ZMYM1

1.98e-05180204767b062f2ef7e20f392e00c646f4985c415d40de9
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-Alox5+_Lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERCC2 INPP4B PTPN13 ACSBG1 RADX ZCCHC4 ZMYM1

1.98e-051802047b28363626f4d2a552abde3434cc1df2e2121aba5
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MDM1 TTK MELK FEN1 CAPN6 DEPDC1 RASA4

2.05e-051812047b203b616584cdbd0bbb0e382b2916d0bd49d3526
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TTK MELK GGH FEN1 ZNF282 DEPDC1 CTR9

2.05e-0518120476873c1138b28c130637d06b64981ad11c262e85f
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MDM1 TTK MELK FEN1 CAPN6 DEPDC1 RASA4

2.05e-051812047c748c16fd20d1949d33ff6290dc9d9016c4dc86c
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRK2 TXNDC16 DIP2B LCP1 IL21R TLR1 PPP1R16B

2.20e-05183204720f7b6ec2462032eda957a893ca76d5a5a01333d
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

SYNE2 SYNE1 RNF213 LCP1 IGF2R PCNX1 OGA

2.28e-051842047791f1bcb954aadc63d4117c400537d036f68734d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE4D INPP4B MAP3K4 PTPN13 SYNE2 ANKRD28 USP46

2.53e-051872047e1d6c1194476cf26969e405b0951796fed519f44
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 LRRK2 DNAH14 PRUNE2 SATB2 SYNE1 NMNAT3

2.62e-05188204763a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellCOPD-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

PDE4D MELK SYNE2 SYNE1 STK33 IL21R PPP1R16B

2.62e-051882047186fe1ea328c942910190a4240262c0d8642ea3b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 LRRK2 DNAH14 PIK3CB SYNE2 PRUNE2 SATB2

2.71e-051892047904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PDE4D GPBP1 KDM5D INPP4B SYNE2 DDX60 USP46

2.80e-051902047f6616b3fe7f4962249503c96c06926240066d861
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE4D ACTN1 ITPR1 LCA5 SATB2 MSRA ANO3

2.80e-05190204749e09cdb843b3d889a06a811aa5affae68b25a75
ToppCellCF-Lymphoid-B_cell|CF / Disease state, Lineage and Cell class

MYCBP2 ADAM28 MDN1 STIM2 TLR10 IL21R PPP1R16B

2.80e-051902047374d8fd63c733178acab07682ed1519693efab45
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CLTCL1 ABCA13 LRRK2 ACTN1 PRUNE2 SYNE1 IGF2R

2.89e-051912047d4f77c73311d1149466bbfe4adbd6a301946ec90
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

PDE4D MYO5B LRRK2 DNAH14 PTPN13 STK33 LRP6

2.89e-051912047e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

MBTPS1 MYCBP2 LYST RNF213 ZDHHC17 LNPEP INVS

2.89e-0519120479454f642c3621370fa23640b631301346b300950
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CLTCL1 ABCA13 ACTN1 PRUNE2 SYNE1 PRDM5 SERPINB1

2.99e-051922047072281344d58e85c9a290750b488d0c101f75d54
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

PDE4D MYO5B LRRK2 DNAH14 PTPN13 STK33 LRP6

2.99e-051922047efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MELK ADARB2 NCAPG2 GGH FEN1 DEPDC1 FAM124A

3.09e-051932047516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

INPP4A INPP4B MAP3K4 SYNE2 SYNE1 RNF213 LNPEP

3.09e-0519320479337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellcontrol-Myeloid-Immature_Neutrophils_2|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PDE4D CLTCL1 ABCA13 TTK GGH ANKRD28 DEPDC1

3.09e-05193204733349830e9eba506470ad3661fad5e5a283d20ca
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D MYO5B ALDH1L1 DNAH14 PTPN13 PRUNE2 STK33

3.09e-0519320473866667dd221612589ae50f5c52f73a183a49ce6
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYCBP2 LYST ADAM28 ITPR1 JMJD1C TLR10 PPP1R16B

3.20e-051942047ff661419b697aef51a53fdeac8d37d870d65f491
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TTK MELK NCAPG2 ADAM28 GGH TTF2 DEPDC1

3.20e-051942047590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

SYNE2 SYNE1 RNF213 LCP1 LNPEP UHMK1 PCNX1

3.30e-0519520479990440bda7fac5d00ef80444fab07459be625e1
ToppCellCOVID-19_Severe|World / Disease condition and Cell class

PDE4D ABCA13 ANKRD28 SYNE1 LCP1 IGF2R SERPINB1

3.30e-05195204722f56ccb81967bff54a1f90e949a8dfc2ce0e4ab
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PDE4D MYO5B LRRK2 DNAH14 PTPN13 SYNE1 STK33

3.30e-0519520479406866f99555198a9be311fbd65751b70f35446
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYNE2 SYNE1 RNF213 LCP1 LNPEP UHMK1 PCNX1

3.41e-051962047418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SYNE2 SYNE1 RNF213 LCP1 LNPEP UHMK1 PCNX1

3.41e-0519620476beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

INPP4B MAP3K4 SYNE2 MED23 SYNE1 RNF213 LNPEP

3.52e-05197204757ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellLPS_only-Hematopoietic_Myeloid-Dendritic_cells|LPS_only / Treatment groups by lineage, cell group, cell type

PDSS2 CERS6 LCP1 PKD1L3 TLR10 IL21R TLR1

3.52e-05197204759ddd8ff7dddf3747b988374e1a4d80959db803e
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS19 ABCA10 PRUNE2 TBX3 SYNE1 LGR5 HMCN1

3.52e-0519720470dd71e399f253787fa546a7e90c5373180b89ffd
ToppCellControl-Myeloid-DC2|Myeloid / Condition, Lineage and Cell class

ADAM28 CD207 CAMK1 TLR10 PRCP IL21R PPP1R16B

3.52e-051972047e0ee15188ff0d9df3c3b5ea523553ce18d223c33
ToppCellNS-critical-d_0-4-Myeloid|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LRRK2 NBN LYST QKI LCP1 CYRIB TLR1

3.64e-05198204772d51284d267f102c26f0ae8279ee9e11e69c7e3
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TTK MELK NCAPG2 GGH FEN1 MAD2L2 DEPDC1

3.64e-05198204706888fe2d42ac66ac12157608becd42764e0d034
ToppCellLPS_anti-TNF-Hematopoietic_Myeloid-Dendritic_cells-mDC|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ACTN1 CD207 LCP1 CYRIB TLR10 IL21R TLR1

3.64e-051982047d11097254791e415bf60a847feac81f400f11664
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA13 IRF6 TTK MELK NCAPG2 HOGA1 DEPDC1

3.64e-051982047f088badb90c6c2d916195f5649eda102119c9ac6
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

TTK MELK NCAPG2 GGH FEN1 DEPDC1 KYAT1

3.76e-0519920473d876f172487425b37b2f658dae59e0f293ee76e
ToppCellLeuk-UTI-Lymphocyte-T_NK-T_NK_proliferative|Leuk-UTI / Disease, Lineage and Cell Type

TTK MELK NCAPG2 GGH FEN1 DEPDC1 PRDM5

3.76e-05199204787113d398585076ece86b9098781e817f8ca241b
ToppCell(5)_Dendritic_cell-(52)_cycling_DCs|(5)_Dendritic_cell / shred on Cell_type and subtype

TTK MELK NCAPG2 GGH FEN1 DEPDC1 CAMK1

3.76e-051992047d0ff446a197062b10f37b585f3f8716d6d89e5b7
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRRK2 ACTN1 LYST SYNE1 LCP1 IGF2R SERPINB1

3.76e-051992047b7af2b4fe6866cc8c78cf0f78390aab1b1b389ba
ToppCellControl-Control-Myeloid-Neutrophil|Control / Disease, condition lineage and cell class

ABCA13 LRRK2 ACTN1 LCP1 PRDM5 JMJD1C IGF2R

3.88e-05200204795c41f147a1594d49e73cb56d86d301c3115ce20
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTK MELK NCAPG2 GGH FEN1 MAD2L2 DEPDC1

3.88e-05200204714c9ced92763858f3d35186cd3908bd0f4cfd872
ToppCellLung_Parenchyma-Severe-Myeloid-cDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ADAM28 PRMT9 CD207 LCP1 CYRIB TLR10 IL21R

3.88e-0520020479744d53915c8dc9d5e011cbbb0ac7db44c615ce7
ToppCellParenchyma_COVID-19-Immune-TX-DCs|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ADAM28 PRMT9 CD207 LCP1 CYRIB TLR10 IL21R

3.88e-0520020476237e4b46b196e1d1610b2edc60af4716a6fed25
ToppCellSepsis-URO-Lymphocyte-T/NK-T/NK_proliferative|URO / Disease, condition lineage and cell class

TTK MELK NCAPG2 GGH FEN1 DEPDC1 INVS

3.88e-052002047f277db6cc288a52a5426120c1067608700ee8ccc
ToppCellControl_saline-Endothelial-Endothelial-Vein|Control_saline / Treatment groups by lineage, cell group, cell type

ACTN1 LYST STIM2 HMCN1 TIE1 PRCP RASA4

3.88e-052002047e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Vein|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ACTN1 SYNE2 STIM2 HMCN1 TIE1 PRCP RASA4

3.88e-0520020477eb366b2c5394af7c77650bde6261e7dac67154e
ToppCellTransverse-Dendritic_cell-cycling_DCs|Dendritic_cell / Region, Cell class and subclass

TTK MELK NCAPG2 GGH FEN1 TTF2 DEPDC1

3.88e-052002047617a6a42f7b31eb3c45bdceaf55a591b6de7f154
ToppCellLung_Parenchyma-Severe-Myeloid-cDC-DCs-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAM28 PRMT9 CD207 LCP1 CYRIB TLR10 IL21R

3.88e-052002047b52f7534a5ff504dccc002ebc30836a87e43c123
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTK MELK NCAPG2 GGH FEN1 MAD2L2 DEPDC1

3.88e-05200204738665128b54f4a81b53c961427aed67bf4e2510b
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

INPP4A SYNE2 SYNE1 RNF213 LCP1 LNPEP UHMK1

3.88e-052002047f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-T/NK_proliferative|Leuk-UTI / Disease, condition lineage and cell class

TTK MELK NCAPG2 GGH FEN1 DEPDC1 PRDM5

3.88e-052002047093e97395be23092229521cc55aaaee8befbc149
ToppCellLung_Parenchyma-Severe-Myeloid-cDC-DCs|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ADAM28 PRMT9 CD207 LCP1 CYRIB TLR10 IL21R

3.88e-052002047cb0ba75be8fb2ec47474559911df80d085c4dbc8
ToppCelldroplet-Liver-Npc-21m-Epithelial-Hepatocyte_(Midlobular)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOGA1 PDSS2 SETMAR NMNAT3 MSRA SERPINB1

5.15e-0514320460cd332c128710291a39957d3da22953352f5c382
ToppCelldroplet-Liver-Npc-21m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOGA1 PDSS2 SETMAR NMNAT3 MSRA SERPINB1

5.78e-05146204624e63124116b9a6796ae0495fc69dc6b6af28c38
DrugFluphenazine dihydrochloride [146-56-5]; Down 200; 7.8uM; PC3; HT_HG-U133A

AGPAT3 EXT1 RAD54L2 ITPR1 PIK3CB ZNF107 KYAT1 ZCCHC4 PRKAB1 ZMYM1 ZNF85

1.75e-06198203115880_DN
DiseaseColorectal Carcinoma

ERCC2 ABCA13 ALDH1L1 ADARB2 ABCA10 GGH NF1 PTPRS FEN1 UGT3A2 QKI SATB2 SYNE1 CAPN6 GRIK3 LGR5

2.96e-0570220216C0009402
Diseasedocosapentaenoic acid measurement

AGPAT3 FEN1 STIM2 FADS3

3.31e-05272024EFO_0006809
DiseaseAcquired Polyneuropathy

EPO PNPLA6

1.39e-0432022C0751449
DiseasePolyneuropathy, Familial

EPO PNPLA6

1.39e-0432022C0751448
DiseasePolyneuropathy, Motor

EPO PNPLA6

1.39e-0432022C0271683
DiseasePolyneuropathy, Critical Illness

EPO PNPLA6

1.39e-0432022C0393851
Diseaseanti-Helicobacter pylori serum IgG measurement

TLR10 TLR1

1.39e-0432022EFO_0005247
Diseasecitrate measurement

CLTCL1 CPS1 JMJD1C IGF2R CNOT1

2.14e-04792025EFO_0010114
Diseasefibrinogen measurement, tissue plasminogen activator measurement

DIP2B CPS1 PKD1L3 JMJD1C

2.55e-04452024EFO_0004623, EFO_0004791
Diseasefibrinogen measurement, plasminogen activator inhibitor 1 measurement

DIP2B CPS1 PKD1L3 JMJD1C

2.55e-04452024EFO_0004623, EFO_0004792
Diseasecommon variable immunodeficiency (is_implicated_in)

DCLRE1C IL21R

2.77e-0442022DOID:12177 (is_implicated_in)
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE2 SYNE1

2.77e-0442022cv:CN293514
DiseasePolyneuropathy

EPO PNPLA6

2.77e-0442022C0152025
DiseaseParkinson Disease

LRRK2 ADARB2 NCAPG2 MTA1 IGF2R

3.01e-04852025C0030567
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE2 SYNE1

4.60e-0452022C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE2 SYNE1

4.60e-0452022C0410190
Diseaseneurodegenerative disease (implicated_via_orthology)

LRRK2 GGA3 PNPLA6 GRIK3 NMNAT3 GGA1

5.05e-041452026DOID:1289 (implicated_via_orthology)
Diseasefibrinogen measurement, factor VII measurement

DIP2B CPS1 PKD1L3 JMJD1C

6.77e-04582024EFO_0004619, EFO_0004623
DiseaseColorectal Neoplasms

ERCC2 ABCA13 ABCA10 GGH FEN1 SATB2 SYNE1 LGR5

6.80e-042772028C0009404
DiseaseEmery-Dreifuss muscular dystrophy

SYNE2 SYNE1

6.87e-0462022cv:C0410189
Diseasebrain disease (implicated_via_orthology)

MYCBP2 STIM2

6.87e-0462022DOID:936 (implicated_via_orthology)
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE2 SYNE1

6.87e-0462022C0410189
Diseaseforced expiratory volume, environmental tobacco smoke exposure measurement

PDSS2 GRIK3

6.87e-0462022EFO_0004314, EFO_0008361
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

SYNE2 SPG11 CPS1 LCP1 JMJD1C

7.28e-041032025EFO_0008595, EFO_0020944
DiseasePancytopenia

EPO DNAJC21 FANCL

7.32e-04262023C0030312
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

ARMC2 ITIH3 SYNE2 LCP1 MSRA IGF2R TNKS2

9.30e-042242027EFO_0004530, EFO_0008317
Diseasefibrinogen measurement

ITPR1 DIP2B CPS1 PKD1L3 JMJD1C

9.40e-041092025EFO_0004623
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE2 SYNE1

9.57e-0472022C0751337
Diseasecholesterol in large VLDL measurement

ITIH3 LCP1 JMJD1C IGF2R

1.04e-03652024EFO_0021902
Diseaselipoprotein A measurement

MAP3K4 CPS1 LCP1 IGF2R FAM124A

1.06e-031122025EFO_0006925
Diseasephospholipids:total lipids ratio, intermediate density lipoprotein measurement

SPG11 CPS1 LCP1 JMJD1C

1.17e-03672024EFO_0008595, EFO_0020946
DiseaseHuntington's disease (implicated_via_orthology)

ZDHHC13 ZDHHC17 LCP1

1.35e-03322023DOID:12858 (implicated_via_orthology)
Diseasephosphatidylcholine 38:5 measurement

FEN1 FADS3 NUDCD1

1.48e-03332023EFO_0010387
Diseasecholesterol:total lipids ratio, intermediate density lipoprotein measurement

SYNE2 SPG11 CPS1 LCP1 JMJD1C

1.50e-031212025EFO_0008595, EFO_0020943
Diseaselevel of Phosphatidylcholine (O-18:0_20:4) in blood serum

FEN1 FADS3

1.63e-0392022OBA_2045127
Diseasemetabolite measurement

CLTCL1 ALDH1L1 HOGA1 SYNE2 ICE1 CERS6 CPS1 LCP1 KYAT1 IGF2R ZMYM1

1.75e-0356020211EFO_0004725
Diseasetriacylglycerol 52:4 measurement

AGPAT3 LCP1 CNOT1

1.91e-03362023EFO_0010416
Diseasetriacylglycerol 56:8 measurement

FEN1 LCP1 FADS3

1.91e-03362023EFO_0010435
Diseaseoleoyl-linoleoyl-glycerol (18:1/18:2) [2] measurement

FEN1 LCP1

2.02e-03102022EFO_0800333
Diseasecholesteryl ester measurement

ABCA10 ITIH3 FEN1 LCP1 JMJD1C IGF2R FADS3

2.04e-032572027EFO_0010351
Diseaseoleoyl-linoleoyl-glycerol (18:1/18:2) [1] measurement

FEN1 LCP1

2.46e-03112022EFO_0800332
DiseaseInherited neuropathies

ITPR1 PNPLA6 SPG11

2.59e-03402023C0598589
DiseaseNeoplasm of uncertain or unknown behavior of breast

INPP4B PIK3CB TBX3

2.78e-03412023C0496956
DiseaseBreast adenocarcinoma

INPP4B PIK3CB TBX3

2.78e-03412023C0858252
Diseaseepilepsy

EXT1 OGA C1orf94

2.78e-03412023EFO_0000474
DiseaseOligodontia

IRF6 LRP6

2.94e-03122022C4082304
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE2 SYNE1

2.94e-03122022DOID:11726 (implicated_via_orthology)
Diseasehigh grade glioma (is_implicated_in)

EPO ERCC2 NF1

2.98e-03422023DOID:3070 (is_implicated_in)
DiseaseMalignant neoplasm of breast

ADAMTS19 RTP1 DNAJC21 NBN ACY1 INPP4B GGA3 DAP3 NF1 PIK3CB SYNE2 TBX3 SYNE1 UBR4 GRIK3 GGA1

3.08e-03107420216C0006142
Diseasesphingomyelin measurement

SYNE2 FEN1 DIP2B CERS6 LCP1 JMJD1C FADS3

3.16e-032782027EFO_0010118
Diseaseejection fraction measurement

ADARB2 TXNDC16 HMCN1

3.19e-03432023EFO_0005527
Diseasetriglycerides in large LDL measurement

SYNE2 LCP1 IGF2R

3.19e-03432023EFO_0022319
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

SYNE2 SPG11 CPS1 LCP1 JMJD1C

3.19e-031442025EFO_0004611, EFO_0020943
DiseaseAnemia, Hemolytic, Acquired

EPO SPTB

3.46e-03132022C0002879
DiseaseAnemia, Hemolytic

EPO SPTB

3.46e-03132022C0002878
DiseaseAnemia, Microangiopathic

EPO SPTB

3.46e-03132022C0002889
DiseaseMicroangiopathic hemolytic anemia

EPO SPTB

3.46e-03132022C0221021
Diseaselevel of Phosphatidylcholine (O-16:0_20:4) in blood serum

FEN1 FADS3

3.46e-03132022OBA_2045116
DiseaseSkin Abnormalities

ERCC2 IRF6

3.46e-03132022C0037268
Diseaseobesity (implicated_via_orthology)

PLXNB2 TULP3 ITPR1 PNPLA1 STIM2 AOC3

3.75e-032152026DOID:9970 (implicated_via_orthology)
Diseasebreast cancer (is_implicated_in)

ERCC2 NBN TSG101 ADAM28 PTPN13

3.80e-031502025DOID:1612 (is_implicated_in)
DiseaseHypodontia

IRF6 LRP6

4.02e-03142022C0020608
DiseaseN-acetylglycine measurement

ALDH1L1 CPS1

4.02e-03142022EFO_0021002
Diseasediacylglycerol 38:4 measurement

FEN1 FADS3

4.02e-03142022EFO_0020066
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

SYNE2 SPG11 CPS1 LCP1 JMJD1C MSRA IGF2R

4.05e-032912027EFO_0008317, EFO_0020946
Diseasefibrinogen measurement, coronary artery disease

DIP2B CPS1 LCP1 JMJD1C IGF2R

4.25e-031542025EFO_0001645, EFO_0004623
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

SYNE2 SPG11 LCP1 JMJD1C MSRA IGF2R

4.38e-032222026EFO_0008317, EFO_0020943
Diseasetransient cerebral ischemia (biomarker_via_orthology)

EPO PDE4D ITPR1 PTPN13 NF1

4.61e-031572025DOID:224 (biomarker_via_orthology)
Diseasecis/trans-18:2 fatty acid measurement, trans fatty acid measurement

FEN1 FADS3

4.62e-03152022EFO_0006821, EFO_0006824
Diseaseglycerophospholipid measurement

SYNE2 FEN1 FADS3

4.62e-03492023EFO_0007630
Diseasecholesteryl ester 20:3 measurement

FEN1 LCP1 FADS3

4.62e-03492023EFO_0010347
Diseasedisease recurrence, colon carcinoma

ARMC2 MAP3K4 STK33

5.17e-03512023EFO_0004952, EFO_1001950
Diseaseureidopropionic acid measurement

ADARB2 CPS1

5.25e-03162022EFO_0010542
Diseaselysosomal storage disease (implicated_via_orthology)

GGA3 GGA1

5.25e-03162022DOID:3211 (implicated_via_orthology)
Diseasediacylglycerol 36:2 measurement

FEN1 LCP1

5.25e-03162022EFO_0010355
Diseasehousehold income, smoking status measurement, educational attainment, protein intake measurement, carbohydrate intake measurement, alcohol consumption measurement, body mass index, energy intake measurement

MSRA C1orf94

5.25e-03162022EFO_0004340, EFO_0006527, EFO_0007878, EFO_0009374, EFO_0009695, EFO_0010810, EFO_0010811, EFO_0011015
Diseasecholesterol in small VLDL measurement

ABCA10 LCP1 IGF2R

5.76e-03532023EFO_0022228
Diseaselymphocyte count

EPO PDE4A PDE4D SPTB CDH23 NBN PLXNB2 LYST INPP4B ITPR1 ACSBG1 TTF2 CERS6 CPS1 LCP1 JMJD1C CYRIB DCLRE1C PPA2

5.80e-03146420219EFO_0004587
Diseasemuscular dystrophy (is_implicated_in)

POMT2 SYNE1

5.93e-03172022DOID:9884 (is_implicated_in)
DiseaseMoyamoya Disease

NF1 RNF213

5.93e-03172022C0026654
Diseasesphingomyelin 14:0 measurement

PDE4D SYNE2

5.93e-03172022EFO_0010390
DiseaseLimb Deformities, Congenital

IRF6 TBX3

5.93e-03172022C0206762
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

PIK3CB LNPEP AOC3 OGA

5.95e-031052024DOID:9352 (implicated_via_orthology)
Diseasetotal lipids in medium VLDL

ITIH3 LCP1 IGF2R

6.07e-03542023EFO_0022153
Diseaseplasminogen activator inhibitor 1 measurement

INPP4B MAP3K4 UBR4

6.07e-03542023EFO_0004792
Diseaseresponse to TNF antagonist

QKI CERS6 PKD1L3

6.07e-03542023EFO_0004653
Diseaseplatelet component distribution width

LRRK2 ACTN1 INPP4B ANKRD28 QKI PRUNE2 SYNE1 CPS1 LCP1 JMJD1C TADA1 PPP1R16B

6.07e-0375520212EFO_0007984
DiseaseIschemic stroke, fibrinogen measurement

DIP2B CPS1 JMJD1C

6.38e-03552023EFO_0004623, HP_0002140
DiseaseDiffuse Large B-Cell Lymphoma

PIK3CB CLTC GNA13

6.38e-03552023C0079744
DiseaseBone marrow hypocellularity

DNAJC21 FANCL

6.64e-03182022C1855710
Diseasediacylglycerol 36:3 measurement

FEN1 LCP1

6.64e-03182022EFO_0020062
Diseaseschizophrenia, inflammatory bowel disease

EPO IRF3

6.64e-03182022EFO_0003767, MONDO_0005090
Diseaselevel of Phosphatidylcholine (16:0_22:5) in blood serum

AGPAT3 FADS3

6.64e-03182022OBA_2045079
Diseasetriglycerides in large VLDL measurement

ITIH3 LCP1 JMJD1C

6.71e-03562023EFO_0022178
Diseasetriglycerides in LDL measurement

SYNE2 LCP1 IGF2R

6.71e-03562023EFO_0022320
Diseasefactor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement

DIP2B CPS1 PKD1L3

6.71e-03562023EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
DiseaseIGF-1 measurement

PDE4A PDE4D AGBL5 SRCAP ACY1 SYNE2 TBX3 IGF2R RPL3L

6.73e-034882029EFO_0004627

Protein segments in the cluster

PeptideGeneStartEntry
ADRHNAEAWKQTEPA

AGBL5

381

Q8NDL9
DEPTNHLDLNAVIWL

ABCF1

476

Q8NE71
TPQEINGKWDHVRQL

ACTN1

596

P12814
LQAADPAISQAWIKH

ARHGEF25

446

Q86VW2
ASHWKQAAVVLDNPI

PRMT9

806

Q6P2P2
HTEILKLFPQAAWQE

ABCA10

1451

Q8WWZ4
WAHDLQQNIALPATK

ADAM28

176

Q9UKQ2
HWETEFKPVAQQLLN

ARMC2

836

Q8NEN0
NARDKNWQTPLHIAA

ANKRD28

101

O15084
QDHFQEIEKIWSSPN

ABCA13

2981

Q86UQ4
EIGWIPLHKAAVQLN

ASB14

81

A6NK59
IWNHPDVLYEALQKE

RAD54L2

621

Q9Y4B4
IWIHQDTPQDSLDKT

C1orf94

51

Q6P1W5
HSADVNARDKLWQTP

ANKRD52

96

Q8NB46
NARDKLWQTPLHVAA

ANKRD52

101

Q8NB46
KNDGHLEPVTAWEVQ

HSD11B1L

281

Q7Z5J1
PAHWNQVVSEAEKIV

PDSS2

46

Q86YH6
ITLLDINDNHPTWKD

CDH23

766

Q9H251
RNLDGQKEWVHVAPL

PHYKPL

156

Q8IUZ5
KRGIHDASIPQWEND

ANO3

726

Q9BYT9
VDWHFLLESQAPKTI

AOC3

411

Q16853
RVTLQEWNDPLDHDL

RASA4

711

O43374
EWNDPLDHDLEAQLI

RASA4

716

O43374
RVTLQEWNDPLDHDL

RASA4B

711

C9J798
EWNDPLDHDLEAQLI

RASA4B

716

C9J798
KPNWEHLNEDLHVLI

QKI

141

Q96PU8
SWSVAPKNALVQLHE

ADARB2

121

Q9NS39
IETWHKPDLGTQENV

PITPNA

111

Q00169
SPKHILQWQAVLDEE

ADAMTS19

706

Q8TE59
PAHDKLWNQLEAEIH

GOPC

231

Q9HD26
PQAFWTKHAQTEIIE

INPP4A

76

Q96PE3
EELLKVFWENHDPTQ

MSRA

131

Q9UJ68
VDALLWQPHSSKQDD

NUDCD1

461

Q96RS6
WLRFVHEAPSQEQKN

PRDM5

81

Q9NQX1
VEWQSKNPFIHLDDD

MELK

271

Q14680
IWLTDKQPEEHNFSD

RADX

201

Q6NSI4
QEKNHPWLELSDVHR

POLDIP2

221

Q9Y2S7
HRVFQDKQIEDLWLP

PNPLA6

1071

Q8IY17
EPTEKEYDWLQHLAN

MDN1

1286

Q9NU22
QWEDAQKLQHRLIEP

HOGA1

261

Q86XE5
IKDFPWILADEQDVH

MAD2L2

166

Q9UI95
LAHLKESQPAIWNRD

MDC1

416

Q14676
AIDPEDKWHQRAQQL

JHY

311

Q6NUN7
HPFVDKVWELTANNV

MBTPS1

316

Q14703
NTWVHSTNIPIDKEE

ITPR1

396

Q14643
REPNHNKSLAAGVWE

GPBP1

146

Q86WP2
EIDFLRSNPKIWNVH

EIF3L

211

Q9Y262
QEIKELGELSPHWDN

INPP4B

281

O15327
QSPLHWLADLAEQKA

JMJD1C

2006

Q15652
QWLDEVKQALAPSAH

KDM5D

916

Q9BY66
ISNPEHLTEWLQSVK

DDX60

921

Q8IY21
VSEKPQGLSHQEWID

FSIP2

1141

Q5CZC0
LQEAIDNVLAWIHPD

FAM124A

61

Q86V42
EKNLVIAHEGDPAWR

PCNX1

1886

Q96RV3
ALHKPENQDIDWGAL

LCP1

376

P13796
QDEDTIHIWKTNSLP

PLXNB2

1671

O15031
EIQNLQEDWDHFEPL

PDPR

321

Q8NCN5
TWADLVHPDAQEILD

PDE4A

656

P27815
WADLVHPDAQDILDT

PDE4D

686

Q08499
SDFVKENSPEHWLQN

MED23

901

Q9ULK4
HDPQISKSLEWNGAI

MDM1

61

Q8TC05
LQNKSDDLPHWVLSA

DEPDC1

236

Q5TB30
LAEILQWRAQATPDH

DIP2B

991

Q9P265
PLTSQDIQHLKDWIS

PRCP

266

P42785
QASLEGATQPHKEWV

PNPLA1

301

Q8N8W4
TKINDPDDIAVNWVA

LRP5L

31

A4QPB2
GQHRQVLVWKDLDSP

LRP6

736

O75581
WDINLPHEVQNLEKH

LRRK2

2496

Q5S007
NLSPEEEQGLWKQSH

FAM76B

191

Q5HYJ3
GKLPRWIQEHLTDAN

ERCC2

691

P18074
NKWEEPGHLTLDLQS

LCA5

356

Q86VQ0
DDDWEALIHQLKINP

LNPEP

706

Q9UIQ6
LAHKIQSPQEWEAIQ

GGA1

51

Q9UJY5
AHKIQSPQEWEALQA

GGA3

51

Q9NZ52
IPEKHINHAAALQWT

JRKL

471

Q9Y4A0
DAREKLHIPWGDNSN

GNA13

101

Q14344
LALKWHPDKNLDNAA

DNAJC21

26

Q5F1R6
ITWHKDGQPLQEDEA

HMCN1

2511

Q96RW7
PVGNWQKHNVDDSLL

PTPRS

471

Q13332
PKDPWRHAQNVTVDE

PPP1R37

61

O75864
EHKLQFWAVTAENEP

GBA

261

P04062
LQHPWIAGDTALDKN

CAMK1

271

Q14012
NVNAKDNELWTPLHA

PPP1R16B

126

Q96T49
NIHPWVKQIDTLAAE

CPS1

936

P31327
PENWLHKEAHQLFLE

FEN1

271

P39748
WEEKPKSHEAIQALN

ICE1

416

Q9Y2F5
VTVYNPELDKWHNLE

KLHL11

471

Q9NVR0
VLHLQKADGDVPQWE

DCLRE1C

476

Q96SD1
VPWDQLENEDSSVHI

EXT1

66

Q16394
EWKNLDGISHAPNAV

GGH

251

Q92820
SDWFKEALQINQDHP

CTR9

551

Q6PD62
SPKEAENLPLWQHIS

C1orf112

521

Q9NSG2
SSQPWEPLQLHVDKA

EPO

111

P01588
KVQEAVLDKWVNDPH

GOLPH3

216

Q9H4A6
LELSVPEKVNNAQWD

ACSBG1

61

Q96GR2
PHNVTWADLKNTEEA

CERS6

16

Q6ZMG9
EALVWLFHQKPESLN

HSD17B7

266

P56937
EKVVKIPENHNFDWQ

DNAH14

1556

Q0VDD8
ESQENIFLPSKWQHL

LYST

1581

Q99698
LVHDPANWVSVDKNS

CDH26

431

Q8IXH8
HIWLQLEGPKENASR

KHNYN

51

O15037
AIQHPADEKLQEKAW

CYRIB

66

Q9NUQ9
HEWTKPENLDFIEVN

SERPINB1

256

P30740
QSEELKEGWNPHLLL

IL21R

226

Q9HBE5
ETVTKDILAPNLQWH

DNAAF5

651

Q86Y56
PLEEKHSAENNWIEE

DNAL1

151

Q4LDG9
NNHKPREWLEIDLGE

DCBLD1

306

Q8N8Z6
NVDNPHVSAIVEKWS

GRIK3

286

Q13003
IPNHKEQEWDPQKTE

CAPN6

101

Q9Y6Q1
ALQSEVPKDSTHQWL

CREB3

281

O43889
EQIRAHDQPGDKWLV

FADS3

26

Q9Y5Q0
QPEKGTELQFEHLNW

SAMD15

531

Q9P1V8
LKWQHEEAAEAPSLA

DRP2

806

Q13474
SGIITPIHEQWEKAN

PSMF1

136

Q92530
EDPEYDVQSKQWLTH

PTCHD3

331

Q3KNS1
HLWLDDNALTEIPVQ

LGR5

166

O75473
WPERHVLQNLETFEK

MTBP

556

Q96DY7
NWTPLKNDLENHLED

PTPN13

1766

Q12923
DPNIQDKEGRTALHW

INVS

481

Q9Y283
IPWKHGLRQDAQQED

IRF3

36

Q14653
HSPQQEEENTIFKAW

IRF6

46

O14896
QALLETSHQWPKQRE

MROH5

311

Q6ZUA9
VAAKARAHILPWVDN

MROH5

386

Q6ZUA9
PQASHSLKNLLEEEW

MAP3K4

716

Q9Y6R4
HLTWLRNKILNNDPE

NRK

1276

Q7Z2Y5
LSALVRHAEPEQNWE

IGF2R

486

P11717
LENNWLQHEKAPTEE

DAP3

361

P51398
DSWDLIIDPNLKHNV

RTP1

61

P59025
SRVKLQHLPAQEQWD

PLEKHN1

226

Q494U1
PAHRITAKELLDNQW

STK33

366

Q9BYT3
DDPKVHLEAKELWDQ

TBX3

101

O15119
EDHDEALKNTWNLHP

PRUNE2

806

Q8WUY3
TLNSIWNVEDHINPK

POMT2

511

Q9UKY4
SEHDSLWVKNELIPN

TLR10

641

Q9BXR5
PEHKEINHLNDQWLD

SYNE1

4206

Q8NF91
HWLKQADIVTFPEIN

SYNE1

4576

Q8NF91
KEVPFETLAQWNLEH

SYNE2

611

Q8WXH0
KQWETLEPLHLEAEN

SYNE2

2711

Q8WXH0
TKLWHPNHEELQQDK

TADA1

306

Q96BN2
KLSRNIHLWDPENSV

FANCL

266

Q9NW38
IHLWDPENSVLQNLK

FANCL

271

Q9NW38
WKNKEQHLSENEPVD

NBN

501

O60934
IKRAPVIWDNIHAND

OGA

271

O60502
WAQARLEKQVPVHSV

RPL3L

196

Q92901
ALEHVPNSVRLWKAA

PRPF6

396

O94906
PFNLTKTIQQDEWHL

TMEM178A

156

Q8NBL3
ENGALHVTKDLLWEP

TAF1C

46

Q15572
TWKEHLVQATPENLQ

ITIH3

331

Q06033
NPWVEFVKLASEHDV

KYAT1

16

Q16773
KDEEYTWVLNPEHLQ

PKD1L3

586

Q7Z443
KLEDLPAEQWNHATV

SATB2

161

Q9UPW6
KDWTEHANSPVIINE

SLITRK2

541

Q9H156
LDKWVPHELTENQKN

SETMAR

456

Q53H47
PKLTSVHENLNSWIE

MYCBP2

2081

O75592
PNLEEIEHLNWSEAL

ARHGAP5

351

Q13017
DWKLIAINANDPEAS

PPA2

201

Q9H2U2
SSPNKESNEEEQVWH

PPA2

316

Q9H2U2
TQVWEAHNPLTDKQI

MTA1

196

Q13330
SEVSGKNDHIWNEPL

PIK3CB

371

P42338
KNDHIWNEPLEFDIN

PIK3CB

376

P42338
VTQRNKQPWHPDEDD

SRCAP

386

Q6ZRS2
HDSFWVKNELLPNLE

TLR1

646

Q15399
HNVRLWDEESAQLLP

SSH3

376

Q8TE77
PNRISHGEVLEWQKT

SRRT

651

Q9BXP5
KNISDIHPESFNLQW

TM4SF20

131

Q53R12
LAWQHDLEVNDKAPA

PRKAB1

61

Q9Y478
PAEAIHNWIRGNDKV

ALDH1L1

216

O75891
EKEWQRLQSNPHLKE

ACY1

231

Q03154
LPEVAKEQGWDHIQT

AMMECR1

256

Q9Y4X0
PKVLRAAEQAHLWAE

CLTC

1346

Q00610
PKVLRAAEQAHLWAE

CLTCL1

1346

P53675
HFTVDKQNISLWPRE

CD207

11

Q9UJ71
VDNWLPTEHAQAKSN

NCAPG2

726

Q86XI2
LNPTEPDHAIQWDKS

CNOT11

301

Q9UKZ1
QVWPEANQHFSKEID

CNOT1

831

A5YKK6
EWKHPQSDLLGLIQV

TSG101

116

Q99816
DPDLHNSLVWILEND

SMURF2

526

Q9HAU4
IESQPWEDSLKDGHQ

SPG11

2246

Q96JI7
KKQEESQFHPLEWLA

RNF213

3591

Q63HN8
HFAQDLWPEQNIKDS

ZNF107

11

Q9UII5
SHFPQDLWAEQDIKD

ZNF100

111

Q8IYN0
GLENHITILPAQEWK

TXNDC16

726

Q9P2K2
RQPDKENVSLLHWAA

ZDHHC13

76

Q8IUH4
EDIPLDEKEAAQWLH

AGPAT3

261

Q9NRZ7
NHLDSWIPDTNDEKV

SPEM3

106

A0A1B0GUW6
QLKSLIQIDLHDNPW

SLITRK5

551

O94991
SVPDALQKWLQLTHE

STIM2

346

Q9P246
SDSEIQLTWKHPEAL

TIE1

656

P35590
VGLLNHQWLKETDVP

SUN3

61

Q8TAQ9
LQKAADPWVLKHSEL

SOGA1

876

O94964
DPWVLKHSELEKQDN

SOGA1

881

O94964
LDIHQDLDWNPKVST

USP47

1286

Q96K76
VLHQLDSIDLWNPDA

NF1

551

P21359
AFLEHLWKNLQDPSN

RRN3P1

6

Q2M238
NDTSVHWFPVQKLEQ

SRRD

291

Q9UH36
HPQIEARIKEVSAQW

SPTB

711

P11277
NVADLWKFTPLHEAA

TNKS2

586

Q9H2K2
PDKENVTLLHWAAIN

ZDHHC17

86

Q8IUH5
QWLQPEAHSKEQILE

ZSCAN22

76

P10073
EPAENNKPELTWVHE

USP46

156

P62068
VDFSKEEWQHLDPAQ

ZNF41

76

P51814
HWQIPELARKVNTEQ

TTK

406

P33981
QSQDDSHKELPIFWI

ZCCHC4

301

Q9H5U6
HFAQDLWPEQNIKDS

ZNF85

81

Q03923
EEFEWLQQHTEPLAA

XPNPEP2

636

O43895
WNEPLNETTAKHVQE

ZMYM1

1001

Q5SVZ6
HLAANVKIVDWLPQS

UGT3A2

341

Q3SY77
DHGLLPREEWQAKVA

THRSP

71

Q92748
LLIWQHKASAQGDPD

UBR4

761

Q5T4S7
HADLKPRNILWSAEN

UHMK1

156

Q8TAS1
ENLVELHNKAPVWNS

TULP3

356

O75386
AHDILSWIKQEEQPY

ZNF282

361

Q9UDV7
WARIILDEAHNVKNP

TTF2

731

Q9UNY4
WKQLEDSHEDPQGLL

ZNF554

186

Q86TJ5
ASQLLEHPENLAWID

LRRC51

71

Q96E66
DEEIIQNWHLPERFK

LRRIQ3

161

A6PVS8
WPNSEKHVDQEDAIE

MYO5B

1291

Q9ULV0
TFQTPNLWKDAHIQE

NMNAT3

141

Q96T66