Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	sulfate adenylyltransferase (ATP) activity	PAPSS2 PAPSS1	1.35e-05	2	74	2	GO:0004781
GeneOntologyMolecularFunction	sulfate adenylyltransferase activity	PAPSS2 PAPSS1	1.35e-05	2	74	2	GO:0004779
GeneOntologyMolecularFunction	adenylylsulfate kinase activity	PAPSS2 PAPSS1	1.35e-05	2	74	2	GO:0004020
GeneOntologyMolecularFunction	bone sialoprotein binding	ANXA2 ANXA2P2	1.35e-05	2	74	2	GO:0044730
GeneOntologyMolecularFunction	phospholipase A2 inhibitor activity	ANXA2 ANXA2P2	1.35e-04	5	74	2	GO:0019834
GeneOntologyMolecularFunction	alpha-catenin binding	PKP3 NUMB	8.73e-04	12	74	2	GO:0045294
GeneOntologyMolecularFunction	phospholipase inhibitor activity	ANXA2 ANXA2P2	1.03e-03	13	74	2	GO:0004859
GeneOntologyBiologicalProcess	positive regulation of receptor binding	ANXA2 ANXA2P2 PLCL2	2.26e-06	8	72	3	GO:1900122
GeneOntologyBiologicalProcess	lung development	TGFBR2 NPHP3 ANXA2 ANXA2P2 LAMA5 NUMB GPSM2 PGR	4.39e-06	269	72	8	GO:0030324
GeneOntologyBiologicalProcess	respiratory tube development	TGFBR2 NPHP3 ANXA2 ANXA2P2 LAMA5 NUMB GPSM2 PGR	4.89e-06	273	72	8	GO:0030323
GeneOntologyBiologicalProcess	respiratory system development	TGFBR2 NPHP3 ANXA2 ANXA2P2 LAMA5 NUMB GPSM2 PGR	1.10e-05	305	72	8	GO:0060541
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein particle receptor binding	ANXA2 ANXA2P2	1.20e-05	2	72	2	GO:1905597
GeneOntologyBiologicalProcess	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	PAPSS2 PAPSS1	1.20e-05	2	72	2	GO:0050428
GeneOntologyBiologicalProcess	purine ribonucleoside bisphosphate biosynthetic process	PAPSS2 PAPSS1	1.20e-05	2	72	2	GO:0034036
GeneOntologyBiologicalProcess	positive regulation of receptor recycling	ANXA2 ANXA2P2 DAB2	3.21e-05	18	72	3	GO:0001921
GeneOntologyBiologicalProcess	positive regulation of receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2	3.60e-05	3	72	2	GO:1905602
GeneOntologyBiologicalProcess	negative regulation of low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2	3.60e-05	3	72	2	GO:0032804
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein particle clearance	ANXA2 ANXA2P2	7.18e-05	4	72	2	GO:1905581
GeneOntologyBiologicalProcess	negative regulation of receptor catabolic process	ANXA2 ANXA2P2	7.18e-05	4	72	2	GO:2000645
GeneOntologyBiologicalProcess	sulfate assimilation	PAPSS2 PAPSS1	7.18e-05	4	72	2	GO:0000103
GeneOntologyBiologicalProcess	positive regulation of intracellular cholesterol transport	ANXA2 ANXA2P2	7.18e-05	4	72	2	GO:0032385
GeneOntologyBiologicalProcess	positive regulation of intracellular sterol transport	ANXA2 ANXA2P2	7.18e-05	4	72	2	GO:0032382
GeneOntologyBiologicalProcess	regulation of receptor binding	ANXA2 ANXA2P2 PLCL2	7.83e-05	24	72	3	GO:1900120
GeneOntologyBiologicalProcess	protein localization to cell periphery	ANXA2 ANXA2P2 PKP3 CPLX1 DAB2 LAMA5 NUMB GPSM2	1.10e-04	422	72	8	GO:1990778
GeneOntologyBiologicalProcess	positive regulation of plasma membrane repair	ANXA2 ANXA2P2	1.19e-04	5	72	2	GO:1905686
GeneOntologyBiologicalProcess	regulation of low-density lipoprotein particle receptor binding	ANXA2 ANXA2P2	1.19e-04	5	72	2	GO:1905595
GeneOntologyBiologicalProcess	positive regulation of intracellular lipid transport	ANXA2 ANXA2P2	1.19e-04	5	72	2	GO:0032379
GeneOntologyBiologicalProcess	regulation of receptor recycling	ANXA2 ANXA2P2 DAB2	1.71e-04	31	72	3	GO:0001919
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein receptor activity	ANXA2 ANXA2P2	1.79e-04	6	72	2	GO:1905599
GeneOntologyBiologicalProcess	positive regulation of protein binding	NPHP3 ANXA2 ANXA2P2 PLCL2	2.23e-04	85	72	4	GO:0032092
GeneOntologyBiologicalProcess	regulation of low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2	2.50e-04	7	72	2	GO:0032803
GeneOntologyBiologicalProcess	low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2	2.50e-04	7	72	2	GO:0032802
GeneOntologyBiologicalProcess	low-density lipoprotein receptor particle metabolic process	ANXA2 ANXA2P2	2.50e-04	7	72	2	GO:0032799
GeneOntologyBiologicalProcess	regulation of receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2	3.32e-04	8	72	2	GO:1905600
GeneOntologyBiologicalProcess	regulation of plasma membrane repair	ANXA2 ANXA2P2	3.32e-04	8	72	2	GO:1905684
GeneOntologyBiologicalProcess	receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2	6.48e-04	11	72	2	GO:0090118
GeneOntologyBiologicalProcess	translation at presynapse	RPL36A RPS27A RPL7	6.70e-04	49	72	3	GO:0140236
GeneOntologyBiologicalProcess	translation at synapse	RPL36A RPS27A RPL7	7.11e-04	50	72	3	GO:0140241
GeneOntologyBiologicalProcess	translation at postsynapse	RPL36A RPS27A RPL7	7.11e-04	50	72	3	GO:0140242
GeneOntologyBiologicalProcess	protein localization to membrane	ANXA2 ANXA2P2 PKP3 FRMPD1 CPLX1 DAB2 LAMA5 NUMB SRP72	7.52e-04	705	72	9	GO:0072657
GeneOntologyBiologicalProcess	positive regulation of lipoprotein particle clearance	ANXA2 ANXA2P2	7.75e-04	12	72	2	GO:0010986
GeneOntologyBiologicalProcess	regulation of intracellular sterol transport	ANXA2 ANXA2P2	7.75e-04	12	72	2	GO:0032380
GeneOntologyBiologicalProcess	regulation of intracellular cholesterol transport	ANXA2 ANXA2P2	7.75e-04	12	72	2	GO:0032383
GeneOntologyBiologicalProcess	regulation of intracellular lipid transport	ANXA2 ANXA2P2	9.14e-04	13	72	2	GO:0032377
GeneOntologyBiologicalProcess	protein localization to plasma membrane	ANXA2 ANXA2P2 PKP3 DAB2 LAMA5 NUMB	9.38e-04	324	72	6	GO:0072659
GeneOntologyBiologicalProcess	receptor recycling	ANXA2 ANXA2P2 DAB2	9.39e-04	55	72	3	GO:0001881
GeneOntologyCellularComponent	AnxA2-p11 complex	ANXA2 ANXA2P2	3.60e-05	3	73	2	GO:1990665
GeneOntologyCellularComponent	PCSK9-AnxA2 complex	ANXA2 ANXA2P2	3.60e-05	3	73	2	GO:1990667
GeneOntologyCellularComponent	myelin sheath adaxonal region	ANXA2 ANXA2P2	2.50e-04	7	73	2	GO:0035749
GeneOntologyCellularComponent	pinosome	ANXA2 ANXA2P2	6.48e-04	11	73	2	GO:0044352
GeneOntologyCellularComponent	macropinosome	ANXA2 ANXA2P2	6.48e-04	11	73	2	GO:0044354
GeneOntologyCellularComponent	preribosome	RPS4X PES1 UTP20 RPS27A	6.83e-04	114	73	4	GO:0030684
GeneOntologyCellularComponent	cytosolic ribosome	RPL36A RPS4X RPS27A RPL7	9.36e-04	124	73	4	GO:0022626
GeneOntologyCellularComponent	nuclear matrix	RNASEL POLA1 ANXA2 ANXA2P2	1.47e-03	140	73	4	GO:0016363
GeneOntologyCellularComponent	Schmidt-Lanterman incisure	ANXA2 ANXA2P2	1.58e-03	17	73	2	GO:0043220
GeneOntologyCellularComponent	cornified envelope	ANXA2 ANXA2P2 PKP3	1.81e-03	69	73	3	GO:0001533
Domain	TPR_7	NPHP3 TONSL GPSM2	6.74e-06	10	73	3	PF13176
Domain	APS_kinase	PAPSS2 PAPSS1	1.51e-05	2	73	2	IPR002891
Domain	Sulphate_adenylyltransferase	PAPSS2 PAPSS1	1.51e-05	2	73	2	IPR002650
Domain	ATP-Sase_PUA-like_dom	PAPSS2 PAPSS1	1.51e-05	2	73	2	IPR025980
Domain	Sulfurylase_cat_dom	PAPSS2 PAPSS1	1.51e-05	2	73	2	IPR024951
Domain	ATP-sulfurylase	PAPSS2 PAPSS1	1.51e-05	2	73	2	PF01747
Domain	PUA_2	PAPSS2 PAPSS1	1.51e-05	2	73	2	PF14306
Domain	DAPK1	DAPK1 DAPK3	4.51e-05	3	73	2	IPR020676
Domain	PID	DAB1 DAB2 NUMB	1.75e-04	28	73	3	PF00640
Domain	TFR_dimer	NAALAD2 FOLH1	2.24e-04	6	73	2	PF04253
Domain	-	NAALAD2 FOLH1	2.24e-04	6	73	2	1.20.930.40
Domain	PID	DAB1 DAB2 NUMB	2.62e-04	32	73	3	PS01179
Domain	TFR-like_dimer_dom	NAALAD2 FOLH1	3.12e-04	7	73	2	IPR007365
Domain	PTB	DAB1 DAB2 NUMB	5.10e-04	40	73	3	SM00462
Domain	Ribosomal_zn-bd	RPL36A RPS27A	5.33e-04	9	73	2	IPR011332
Domain	PTB/PI_dom	DAB1 DAB2 NUMB	5.49e-04	41	73	3	IPR006020
Domain	Rossmann-like_a/b/a_fold	LARS1 PAPSS2 PAPSS1	6.32e-04	43	73	3	IPR014729
Domain	-	LARS1 PAPSS2 PAPSS1	6.32e-04	43	73	3	3.40.50.620
Domain	Peptidase_M28	NAALAD2 FOLH1	9.70e-04	12	73	2	IPR007484
Domain	Peptidase_M28	NAALAD2 FOLH1	9.70e-04	12	73	2	PF04389
Domain	TPR_8	TONSL SRP72 GPSM2	1.17e-03	53	73	3	PF13181
Domain	TPR	NPHP3 TONSL SRP72 GPSM2	1.64e-03	129	73	4	SM00028
Domain	TPR_repeat	NPHP3 TONSL SRP72 GPSM2	1.83e-03	133	73	4	IPR019734
Domain	PUA-like_domain	PAPSS2 PAPSS1	2.47e-03	19	73	2	IPR015947
Domain	PA	NAALAD2 FOLH1	2.47e-03	19	73	2	PF02225
Domain	PA_domain	NAALAD2 FOLH1	2.47e-03	19	73	2	IPR003137
Domain	TPR-contain_dom	NPHP3 TONSL SRP72 GPSM2	2.83e-03	150	73	4	IPR013026
Domain	TPR_REGION	NPHP3 TONSL SRP72 GPSM2	3.98e-03	165	73	4	PS50293
Domain	TPR	NPHP3 TONSL SRP72 GPSM2	3.98e-03	165	73	4	PS50005
Domain	TPR_1	NPHP3 SRP72 GPSM2	5.28e-03	90	73	3	PF00515
Domain	TPR_1	NPHP3 SRP72 GPSM2	5.28e-03	90	73	3	IPR001440
Domain	PH_dom-like	IRS4 FRMPD1 PLCL2 DAB1 DAB2 NUMB	6.39e-03	426	73	6	IPR011993
Domain	Arm	PKP3 ANKAR	6.51e-03	31	73	2	PF00514
Domain	TNFR/NGFR_Cys_rich_reg	TNFRSF9 LAMA5	7.36e-03	33	73	2	IPR001368
Pathway	REACTOME_SELENOAMINO_ACID_METABOLISM	RPL36A RPS4X LARS1 RPS27A PAPSS2 PAPSS1 RPL7	3.98e-07	118	56	7	M27170
Pathway	REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES	NAALAD2 RPL36A FOLH1 RPS4X ASMT LARS1 RPS27A PAPSS2 PAPSS1 RPL7	1.51e-06	366	56	10	M727
Pathway	REACTOME_MAJOR_PATHWAY_OF_RRNA_PROCESSING_IN_THE_NUCLEOLUS_AND_CYTOSOL	RPL36A RPS4X PES1 UTP20 RPS27A RPL7	7.62e-05	180	56	6	MM15324
Pathway	REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE	RPL36A RPS4X SRP72 RPS27A RPL7	8.35e-05	113	56	5	M567
Pathway	REACTOME_RRNA_PROCESSING	RPL36A RPS4X PES1 UTP20 RPS27A RPL7	1.56e-04	205	56	6	M27685
Pathway	REACTOME_TRANSPORT_AND_SYNTHESIS_OF_PAPS	PAPSS2 PAPSS1	2.30e-04	6	56	2	MM14679
Pathway	REACTOME_TRANSPORT_AND_SYNTHESIS_OF_PAPS	PAPSS2 PAPSS1	2.30e-04	6	56	2	M27027
Pathway	WP_CYTOPLASMIC_RIBOSOMAL_PROTEINS	RPL36A RPS4X RPS27A RPL7	2.96e-04	81	56	4	MM15911
Pathway	KEGG_MEDICUS_REFERENCE_TRANSLATION_INITIATION	RPL36A RPS4X RPS27A RPL7	2.96e-04	81	56	4	M47786
Pathway	KEGG_RIBOSOME	RPL36A RPS4X RPS27A RPL7	4.07e-04	88	56	4	M189
Pathway	WP_CYTOPLASMIC_RIBOSOMAL_PROTEINS	RPL36A RPS4X RPS27A RPL7	4.07e-04	88	56	4	M39495
Pathway	REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION	RPL36A RPS4X RPS27A RPL7	5.22e-04	94	56	4	M29556
Pathway	REACTOME_NONSENSE_MEDIATED_DECAY_NMD_INDEPENDENT_OF_THE_EXON_JUNCTION_COMPLEX_EJC	RPL36A RPS4X RPS27A RPL7	5.66e-04	96	56	4	MM15705
Pathway	REACTOME_CASPASE_ACTIVATION_VIA_DEPENDENCE_RECEPTORS_IN_THE_ABSENCE_OF_LIGAND	DAPK1 DAPK3	6.83e-04	10	56	2	M866
Pathway	REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY	RPL36A RPS4X RPS27A RPL7	7.11e-04	102	56	4	M29813
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	TNRC18 SULF2 RPL36A ANXA2 RPS4X PKP3 PES1 ZRANB2 LARS1 UTP20 RPS27A SF3B2 RPL7	1.45e-09	655	75	13	35819319
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	RPL36A ANXA2 RPS4X ANXA2P2 PKP3 PES1 LARS1 DAB2 NUMB SRP72 UTP20 RPS27A SF3B2 RPL7	1.38e-08	949	75	14	36574265
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	IRS4 RPL36A ATRX PEBP1 POLA1 ANXA2 RPS4X RGS22 PES1 ZRANB2 LARS1 SRP72 UTP20 ME2 SF3B2 RPL7	5.06e-08	1425	75	16	30948266
Pubmed	Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.	IRS4 RPL36A ANXA2 RPS4X PES1 ZRANB2 LARS1 SRP72 RPS27A SF3B2 RPL7	1.29e-07	641	75	11	36057605
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	TNRC18 IRS4 UBN1 SETBP1 TONSL TSPYL2 DAB2 NUMB NYAP1	3.79e-07	430	75	9	35044719
Pubmed	Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.	RPL36A RPS4X SRP72 SF3B2 RPL7	9.18e-07	81	75	5	24965446
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	RPL36A ATRX PES1 LAMA5 SRP72 SF3B2 RPL7	1.23e-06	251	75	7	28077445
Pubmed	Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling.	DAB1 DAB2 NUMB	2.09e-06	12	75	3	12606711
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	ATRX PEBP1 POLA1 ANXA2 RPS4X LARS1 RPS27A SF3B2 RPL7	2.41e-06	538	75	9	28524877
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PHKB TNRC18 ATRX FOLH1 PKP3 ANKAR SETBP1 FRMPD1 TSPYL2 DAB1 NUMB PBX3 ME2 SGK2	3.17e-06	1489	75	14	28611215
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	NPHP3 PEBP1 ANXA2 RPS4X ANXA2P2 ANKAR CPLX1 DAB1 RPS27A	3.53e-06	564	75	9	21565611
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	IRS4 RPL36A ANXA2 PES1 ZRANB2 LARS1 SRP72 RPS27A SF3B2 RPL7	3.83e-06	731	75	10	29298432
Pubmed	Frmpd1 Facilitates Trafficking of G-Protein Transducin and Modulates Synaptic Function in Rod Photoreceptors of Mammalian Retina.	FRMPD1 GPSM2	4.59e-06	2	75	2	36180221
Pubmed	A member of a family of sulfate-activating enzymes causes murine brachymorphism.	PAPSS2 PAPSS1	4.59e-06	2	75	2	9671738
Pubmed	A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events.	ANXA2 ANXA2P2	4.59e-06	2	75	2	21486955
Pubmed	Lipid raft endocytosis and exosomal transport facilitate extracellular trafficking of annexin A2.	ANXA2 ANXA2P2	4.59e-06	2	75	2	21737841
Pubmed	Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy.	ANXA2 ANXA2P2	4.59e-06	2	75	2	19536308
Pubmed	Structural and biochemical characterization of the interaction between LGN and Frmpd1.	FRMPD1 GPSM2	4.59e-06	2	75	2	23318951
Pubmed	Annexin A2 modulates radiation-sensitive transcriptional programming and cell fate.	ANXA2 ANXA2P2	4.59e-06	2	75	2	23148505
Pubmed	Regulation of the low-dose radiation paracrine-specific anchorage-independent growth response by annexin A2.	ANXA2 ANXA2P2	4.59e-06	2	75	2	19580511
Pubmed	ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.	ANXA2 ANXA2P2	4.59e-06	2	75	2	38290972
Pubmed	The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats.	ANXA2 ANXA2P2	4.59e-06	2	75	2	3013423
Pubmed	Activation of Annexin A2 signaling at the blood-brain barrier in a mouse model of multiple sclerosis.	ANXA2 ANXA2P2	4.59e-06	2	75	2	35064931
Pubmed	Complex Roles of Annexin A2 in Host Blood-Brain Barrier Invasion by Cryptococcus neoformans.	ANXA2 ANXA2P2	4.59e-06	2	75	2	28130864
Pubmed	Selenomethionine promotes ANXA2 phosphorylation for proliferation and protein synthesis of myoblasts and skeletal muscle growth.	ANXA2 ANXA2P2	4.59e-06	2	75	2	36739096
Pubmed	Localization of annexin II in the paranodal regions and Schmidt-Lanterman incisures in the peripheral nervous system.	ANXA2 ANXA2P2	4.59e-06	2	75	2	17549680
Pubmed	Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia.	ANXA2 ANXA2P2	4.59e-06	2	75	2	22517898
Pubmed	Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in mice.	ANXA2 ANXA2P2	4.59e-06	2	75	2	39384746
Pubmed	Anxa2 gene silencing attenuates obesity-induced insulin resistance by suppressing the NF-κB signaling pathway.	ANXA2 ANXA2P2	4.59e-06	2	75	2	30462534
Pubmed	Nuclear localization of PAPS synthetase 1: a sulfate activation pathway in the nucleus of eukaryotic cells.	PAPSS2 PAPSS1	4.59e-06	2	75	2	10657990
Pubmed	Annexin A2 mediates up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells.	ANXA2 ANXA2P2	4.59e-06	2	75	2	20826156
Pubmed	Human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPSS1) and PAPSS2: gene cloning, characterization and chromosomal localization.	PAPSS2 PAPSS1	4.59e-06	2	75	2	10679223
Pubmed	Type II transforming growth factor-beta receptor recycling is dependent upon the clathrin adaptor protein Dab2.	TGFBR2 DAB2	4.59e-06	2	75	2	20881059
Pubmed	Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue.	ANXA2 ANXA2P2	4.59e-06	2	75	2	27468426
Pubmed	Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis.	ANXA2 ANXA2P2	4.59e-06	2	75	2	38092984
Pubmed	Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.	ANXA2 ANXA2P2	4.59e-06	2	75	2	21572519
Pubmed	Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis.	ANXA2 ANXA2P2	4.59e-06	2	75	2	19841537
Pubmed	Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice.	ANXA2 ANXA2P2	4.59e-06	2	75	2	21788340
Pubmed	The Membrane Phospholipid Binding Protein Annexin A2 Promotes Phagocytosis and Nonlytic Exocytosis of Cryptococcus neoformans and Impacts Survival in Fungal Infection.	ANXA2 ANXA2P2	4.59e-06	2	75	2	27371724
Pubmed	Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse.	PAPSS2 PAPSS1	4.59e-06	2	75	2	9771708
Pubmed	Characterization and expression of human bifunctional 3'-phosphoadenosine 5'-phosphosulphate synthase isoforms.	PAPSS2 PAPSS1	4.59e-06	2	75	2	11931637
Pubmed	Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice.	ANXA2 ANXA2P2	4.59e-06	2	75	2	27389701
Pubmed	Annexin A2 Deficiency Exacerbates Neuroinflammation and Long-Term Neurological Deficits after Traumatic Brain Injury in Mice.	ANXA2 ANXA2P2	4.59e-06	2	75	2	31817350
Pubmed	ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3.	ANXA2 ANXA2P2	4.59e-06	2	75	2	37832154
Pubmed	Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation.	ANXA2 ANXA2P2	4.59e-06	2	75	2	17360942
Pubmed	Annexin A2 regulates phagocytosis of photoreceptor outer segments in the mouse retina.	ANXA2 ANXA2P2	4.59e-06	2	75	2	19587120
Pubmed	Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice.	ANXA2 ANXA2P2	4.59e-06	2	75	2	30902828
Pubmed	Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate.	ANXA2 ANXA2P2	4.59e-06	2	75	2	19022301
Pubmed	Cell surface translocation of annexin A2 facilitates glutamate-induced extracellular proteolysis.	ANXA2 ANXA2P2	4.59e-06	2	75	2	24742684
Pubmed	Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections.	ANXA2 ANXA2P2	4.59e-06	2	75	2	32687500
Pubmed	Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.	ANXA2 ANXA2P2	4.59e-06	2	75	2	22453828
Pubmed	Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury.	ANXA2 ANXA2P2	4.59e-06	2	75	2	38253182
Pubmed	Agents that bind annexin A2 suppress ocular neovascularization.	ANXA2 ANXA2P2	4.59e-06	2	75	2	20607799
Pubmed	Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III.	NAALAD2 FOLH1	4.59e-06	2	75	2	19678840
Pubmed	Antitumor immune response induced by DNA vaccine encoding human prostate-specific membrane antigen and mouse 4-1BBL.	TNFRSF9 FOLH1	4.59e-06	2	75	2	20452657
Pubmed	A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study.	ANXA2 ANXA2P2	4.59e-06	2	75	2	31253864
Pubmed	Influence of a glutamate carboxypeptidase II (GCPII) polymorphism (1561C-->T) on plasma homocysteine, folate and vitamin B(12) levels and its relationship to cardiovascular disease risk.	NAALAD2 FOLH1	4.59e-06	2	75	2	12204797
Pubmed	Analysis of partner of inscuteable (mPins) expression in the developing mouse eye.	NUMB GPSM2	4.59e-06	2	75	2	19122831
Pubmed	Annexin A2 is a novel cellular redox regulatory protein involved in tumorigenesis.	ANXA2 ANXA2P2	4.59e-06	2	75	2	22185818
Pubmed	GCPII and its close homolog GCPIII: from a neuropeptidase to a cancer marker and beyond.	NAALAD2 FOLH1	4.59e-06	2	75	2	30844704
Pubmed	Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo.	ANXA2 ANXA2P2	4.59e-06	2	75	2	19628708
Pubmed	Annexin A2 binds to the localization signal in the 3' untranslated region of c-myc mRNA.	ANXA2 ANXA2P2	4.59e-06	2	75	2	15654879
Pubmed	Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasm.	PAPSS2 PAPSS1	4.59e-06	2	75	2	22242175
Pubmed	Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis.	ANXA2 ANXA2P2	4.59e-06	2	75	2	20847146
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	IRS4 RPL36A ATRX RPS4X PES1 ZRANB2 RPS27A RPL7	5.04e-06	441	75	8	31239290
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	IRS4 RPL36A ATRX PEBP1 PES1 LARS1 NUMB RPS27A ME2 SF3B2 RPL7	5.05e-06	934	75	11	33916271
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	PHKB IRS4 RPL36A ADRM1 PEBP1 ANXA2 RPS4X ZRANB2 LARS1 RPS27A SF3B2 RPL7	6.12e-06	1149	75	12	35446349
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	IRS4 UBN1 ATRX ANXA2 RPS4X ANXA2P2 SRP72 DLX1 ZDBF2 RPS27A SF3B2	6.17e-06	954	75	11	36373674
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	RPL36A ANXA2 RPS4X PES1 LARS1 SRP72 RPS27A SF3B2 RPL7	7.09e-06	615	75	9	31048545
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	PEBP1 POLA1 ANXA2 RPS4X PKP3 KIF21A ZRANB2 LARS1 SRP72 RPS27A PAPSS2 SF3B2 RPL7	9.56e-06	1415	75	13	28515276
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	IRS4 RPL36A RPS4X PES1 SRP72 UTP20 RPS27A RPL7	9.76e-06	483	75	8	36912080
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	IRS4 POLA1 RPS4X PES1 SRP72 UTP20 ME2 SF3B2 RPL7	1.14e-05	653	75	9	22586326
Pubmed	STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.	ANXA2 ANXA2P2	1.37e-05	3	75	2	35098646
Pubmed	Annexin A2 promotes angiogenesis after ischemic stroke via annexin A2 receptor - AKT/ERK pathways.	ANXA2 ANXA2P2	1.37e-05	3	75	2	36367512
Pubmed	Revealing Annexin A2 and ARF-6 enrollment during Trypanosoma cruzi extracellular amastigote-host cell interaction.	ANXA2 ANXA2P2	1.37e-05	3	75	2	26416603
Pubmed	Annexin A2 depletion delays EGFR endocytic trafficking via cofilin activation and enhances EGFR signaling and metastasis formation.	ANXA2 ANXA2P2	1.37e-05	3	75	2	23792445
Pubmed	The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.	ANXA2 ANXA2P2	1.37e-05	3	75	2	35413401
Pubmed	Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases.	ANXA2 ANXA2P2	1.37e-05	3	75	2	28694388
Pubmed	High Podocalyxin levels promote cell viability partially through up-regulation of Annexin A2.	ANXA2 ANXA2P2	1.37e-05	3	75	2	27470587
Pubmed	Annexin 2-CXCL12 interactions regulate metastatic cell targeting and growth in the bone marrow.	ANXA2 ANXA2P2	1.37e-05	3	75	2	25139998
Pubmed	Annexins--unique membrane binding proteins with diverse functions.	ANXA2 ANXA2P2	1.37e-05	3	75	2	15169834
Pubmed	Isolation and expression of novel human glutamate carboxypeptidases with N-acetylated alpha-linked acidic dipeptidase and dipeptidyl peptidase IV activity.	NAALAD2 FOLH1	1.37e-05	3	75	2	10085079
Pubmed	A comparison of the biological features of prostate cancer with (PSA+, PSMA+) profile according to RKIP.	FOLH1 PEBP1	1.37e-05	3	75	2	23991415
Pubmed	Annexin A2 reduces PCSK9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9.	ANXA2 ANXA2P2	1.37e-05	3	75	2	24808179
Pubmed	Impaired osteoblast differentiation in annexin A2- and -A5-deficient cells.	ANXA2 ANXA2P2	1.37e-05	3	75	2	25222280
Pubmed	The Annexin a2 Promotes Development in Arthritis through Neovascularization by Amplification Hedgehog Pathway.	ANXA2 ANXA2P2	1.37e-05	3	75	2	26963384
Pubmed	The death-associated protein kinases: structure, function, and beyond.	DAPK1 DAPK3	1.37e-05	3	75	2	16756490
Pubmed	Biochemical characterization of human glutamate carboxypeptidase III.	NAALAD2 FOLH1	1.37e-05	3	75	2	17241121
Pubmed	Macrophage surface expression of annexins I and II in the phagocytosis of apoptotic lymphocytes.	ANXA2 ANXA2P2	1.37e-05	3	75	2	15064349
Pubmed	Annexin A2 links poor myofiber repair with inflammation and adipogenic replacement of the injured muscle.	ANXA2 ANXA2P2	1.37e-05	3	75	2	28334824
Pubmed	Tenascin-c renders a proangiogenic phenotype in macrophage via annexin II.	ANXA2 ANXA2P2	1.37e-05	3	75	2	28857429
Pubmed	Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton.	DAB1 DAB2	1.37e-05	3	75	2	11967127
Pubmed	Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B.	ANXA2 ANXA2P2	1.37e-05	3	75	2	31160583
Pubmed	Constitutive activation of transforming growth factor Beta receptor 1 in the mouse uterus impairs uterine morphology and function.	TGFBR2 PGR	1.37e-05	3	75	2	25505200
Pubmed	Inhibition of ANXA2 regulated by SRF attenuates the development of severe acute pancreatitis by inhibiting the NF-κB signaling pathway.	ANXA2 ANXA2P2	1.37e-05	3	75	2	35900381
Pubmed	Molecular evolution of the transferrin receptor/glutamate carboxypeptidase II family.	NAALAD2 FOLH1	1.37e-05	3	75	2	17160644
Pubmed	Deletion of glutamate carboxypeptidase II (GCPII), but not GCPIII, provided long-term benefits in mice with traumatic brain injury.	NAALAD2 FOLH1	1.37e-05	3	75	2	37349952
Pubmed	Annexin II interactions with the annexin II receptor enhance multiple myeloma cell adhesion and growth in the bone marrow microenvironment.	ANXA2 ANXA2P2	1.37e-05	3	75	2	22223826
Pubmed	Annexin A2 promotes phagophore assembly by enhancing Atg16L⁺ vesicle biogenesis and homotypic fusion.	ANXA2 ANXA2P2	1.37e-05	3	75	2	25597631
Pubmed	Parallel Metabolomics and Lipidomics of a PSMA/GCPII Deficient Mouse Model Reveal Alteration of NAAG Levels and Brain Lipid Composition.	NAALAD2 FOLH1	1.37e-05	3	75	2	38377674
Interaction	RNF113A interactions	TNRC18 SULF2 RPL36A ANXA2 RPS4X PKP3 PES1 ZRANB2 LARS1 UTP20 RPS27A SF3B2 RPL7	1.25e-06	692	74	13	int:RNF113A
Interaction	TNIP1 interactions	SULF2 RPL36A ANXA2 RPS4X ANXA2P2 PKP3 PES1 LARS1 DAB2 NUMB SRP72 UTP20 RPS27A SF3B2 RPL7 BFSP1	6.84e-06	1217	74	16	int:TNIP1
Interaction	ACE2 interactions	IRS4 RPL36A ANXA2 RPS4X ANXA2P2 PES1 ZRANB2 LARS1 DAB2 LAMA5 NUMB SRP72 RPS27A SF3B2 RPL7	9.66e-06	1106	74	15	int:ACE2
Interaction	H2BC9 interactions	PRSS35 FSIP2 TNRC18 SULF2 ATRX RPS4X SETBP1 DAPK1 RPS27A	3.63e-05	446	74	9	int:H2BC9
Interaction	PYHIN1 interactions	RPL36A UBN1 ATRX PES1 LAMA5 SRP72 SF3B2 RPL7	4.98e-05	358	74	8	int:PYHIN1
GeneFamily	Ankyrin repeat domain containing\|Death associated protein kinases	DAPK1 DAPK3	6.30e-05	5	46	2	1021
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	NPHP3 SRP72 GPSM2	3.12e-03	115	46	3	769
GeneFamily	Ankyrin repeat domain containing	RNASEL ANKAR TONSL DAPK1	3.29e-03	242	46	4	403
GeneFamily	S ribosomal proteins	RPS4X RPS27A	3.37e-03	34	46	2	728
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PKP3 ANKAR	5.35e-03	43	46	2	409
GeneFamily	L ribosomal proteins	RPL36A RPL7	7.46e-03	51	46	2	729
Coexpression	GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN	ANXA2 ANXA2P2 KIF21A MCAM SRP72 PAPSS1 DSE	1.52e-06	196	75	7	M4676
Coexpression	TABULA_MURIS_SENIS_BRAIN_MYELOID_MICROGLIAL_CELL_AGEING	ADRM1 PEBP1 ANXA2 RPS4X ANXA2P2 RPS27A SF3B2 RPL7	8.18e-06	356	75	8	MM3684
Coexpression	VANGURP_PANCREATIC_BETA_CELL	PEBP1 RPS4X PAPSS2 RPL7 ADCYAP1	2.57e-05	121	75	5	M45030
Coexpression	LAKE_ADULT_KIDNEY_C7_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S3	PEBP1 RPS4X NUMB RPS27A RPL7	4.35e-05	135	75	5	M39226
Coexpression	BILANGES_SERUM_AND_RAPAMYCIN_SENSITIVE_GENES	RPL36A RPS4X RPS27A RPL7	4.64e-05	69	75	4	M2328
Coexpression	BILANGES_SERUM_AND_RAPAMYCIN_SENSITIVE_GENES	RPL36A RPS4X RPS27A RPL7	5.79e-05	73	75	4	MM1304
Coexpression	HALLMARK_UV_RESPONSE_DN	TGFBR2 ATRX ANXA2 DAB2 ADGRL2	5.91e-05	144	75	5	M5942
CoexpressionAtlas	dev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_1000	PRSS35 TNRC18 ADRM1 KIF21A RGS22 FRMPD1 TSPYL2 IPP NUMB DAPK1 ADGRL2 PAPSS2 ME2	5.71e-06	837	74	13	gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_1000
CoexpressionAtlas	dev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500	PRSS35 RNASEL ANXA2 TSPYL2 DAB1 DAPK1 ADGRL2 CCDC171 ME2	1.57e-05	422	74	9	gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_500
CoexpressionAtlas	dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_1000	PRSS35 TNRC18 SULF2 TSPYL2 DAB1 NUMB DAPK1 ZDBF2 PBX3 CCDC171 ME2 DSE	1.86e-05	797	74	12	gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_1000
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000	PRSS35 TNRC18 RNASEL ANXA2 RGS22 TSPYL2 DAB1 NUMB DAPK1 ADGRL2 CCDC171 ME2	2.00e-05	803	74	12	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_1000
CoexpressionAtlas	dev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000	PRSS35 RNASEL ANXA2 RGS22 FRMPD1 TSPYL2 DAB1 DAPK1 ADGRL2 PBX3 CCDC171 ME2	2.03e-05	804	74	12	gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_1000
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000	PRSS35 SULF2 RNASEL TSPYL2 DAB1 NUMB DAPK1 ADGRL2 PBX3 CCDC171 ME2	4.83e-05	740	74	11	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000	PRSS35 SULF2 RNASEL POLA1 DAB1 NUMB DAPK1 ADGRL2 PBX3 CCDC171 ME2	8.02e-05	783	74	11	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlas	dev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000	PRSS35 TNRC18 RGS22 FRMPD1 TSPYL2 DAB1 NUMB DAPK1 ADGRL2 CCDC171 ME2	8.78e-05	791	74	11	gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_1000
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500	PRSS35 TNRC18 RGS22 TSPYL2 DAB1 DAPK1 ADGRL2 ME2	9.56e-05	414	74	8	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	POLA1 KIF21A SETBP1 DAB1 ZDBF2 CCDC171 ME2	1.46e-04	328	74	7	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K2
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_1000	PRSS35 TNRC18 SULF2 TSPYL2 NUMB DAPK1 ZDBF2 PBX3 CCDC171 ME2 DSE	1.79e-04	858	74	11	gudmap_dev gonad_e11.5_F_GonMes_Sma_1000
CoexpressionAtlas	dev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_1000	PRSS35 TNRC18 ADRM1 KIF21A FRMPD1 TSPYL2 IPP DAPK1 ZDBF2 PAPSS2 CCDC171	2.32e-04	884	74	11	gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_1000
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#2_top-relative-expression-ranked_500	RNASEL DAB1 ADGRL2 PBX3	2.65e-04	89	74	4	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k2_500
CoexpressionAtlas	Endoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	PRSS35 TNRC18 SULF2 ANXA2 DAB1 DAB2 MCAM GPSM2 FHIP2B	2.79e-04	615	74	9	PCBC_ratio_DE_vs_SC_cfr-2X-p05
CoexpressionAtlas	dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_500	RGS22 NUMB DAPK1 ADGRL2 ME2	3.03e-04	168	74	5	gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k2_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500	POLA1 KIF21A SETBP1 DAB1 UTP20 DLX1 ZDBF2 CCDC171	3.14e-04	493	74	8	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500
CoexpressionAtlas	dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_1000	PRSS35 TNRC18 FRMPD1 TSPYL2 CCDC171	3.20e-04	170	74	5	gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k4_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500	IRS4 KIF21A SETBP1 GPSM2 SPSB4 DLX1 ZDBF2 CCDC171	3.27e-04	496	74	8	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500
CoexpressionAtlas	dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_1000	RGS22 FRMPD1 NUMB DAPK1 ADGRL2 ME2	3.32e-04	266	74	6	gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k4_1000
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	RPL36A RPS4X BRME1 RPS27A TNXB RPL7	4.52e-07	169	76	6	84b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRSS35 ANXA2 FRMPD1 DAB2 LAMA5 RPL7	1.07e-06	196	76	6	429de4119c8b2193c992d36a6af84f806730cbee
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRSS35 ANXA2 FRMPD1 DAB2 LAMA5 RPL7	1.07e-06	196	76	6	8c8a73d9d9581b8d9a9babfa93459d12fb9eb3ac
ToppCell	PBMC_fresh-frozen\|World / Compartment, severity and other cell annotations on 10x 3' data (130k)	RPL36A ATRX RPS4X ZRANB2 RPS27A RPL7	1.14e-06	198	76	6	dcc223a0396b8b673e4ed8c6733ec6cd74e9a03a
ToppCell	Control_saline-Epithelial_alveolar-AT_1\|Control_saline / Treatment groups by lineage, cell group, cell type	PRSS35 ANXA2 PKP3 KIF21A DAPK1 PAPSS2	1.14e-06	198	76	6	9b161285df7a4e51618f3517cfc5b8221ba55786
ToppCell	NS-moderate\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RPL36A PEBP1 ANXA2 RPS4X RPS27A RPL7	1.14e-06	198	76	6	47dd7f6bc5f2e989104759fd0b0e0b71baa85453
ToppCell	Caecum-T_cell-Th17\|Caecum / Region, Cell class and subclass	RPL36A MPZL3 RPS4X MCAM RPS27A RPL7	1.17e-06	199	76	6	d0742a8c0aa15e68dce14c3cb46a65acf5afb702
ToppCell	Sigmoid-T_cell-Th17\|Sigmoid / Region, Cell class and subclass	RPL36A MPZL3 RPS4X MCAM RPS27A RPL7	1.17e-06	199	76	6	ff9bbfead7a8c7d1ba910ff1f9c6eb9a9774264c
ToppCell	Sigmoid-T_cell-Th17\|T_cell / Region, Cell class and subclass	RPL36A MPZL3 RPS4X MCAM RPS27A RPL7	1.17e-06	199	76	6	622f2ae4b1850b25f723a0385da49147dfec8285
ToppCell	Caecum-(1)_T_cell-(13)_Th17\|Caecum / shred on region, Cell_type, and subtype	RPL36A MPZL3 RPS4X MCAM RPS27A RPL7	1.17e-06	199	76	6	c67228b3e9e2afd8aa8b6c4358c3a27b0945eb29
ToppCell	Sigmoid-(1)_T_cell-(13)_Th17\|Sigmoid / shred on region, Cell_type, and subtype	RPL36A MPZL3 RPS4X MCAM RPS27A RPL7	1.17e-06	199	76	6	1b39191481faf2e8646a1405e30d8579031bd368
ToppCell	severe-CD8+_T_naive\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TGFBR2 RPL36A PEBP1 RPS4X RPS27A RPL7	1.17e-06	199	76	6	656e639228b3f2dca6955a487e4999e73a69bc51
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RPL36A PEBP1 RPS4X TSPYL2 RPS27A RPL7	1.21e-06	200	76	6	b340b6acf675c75adffb98e560080f966571f594
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Interneuron\|3m / Sample Type, Dataset, Time_group, and Cell type.	FSIP2 RPS4X DLX1 RPS27A PBX3 RPL7	1.21e-06	200	76	6	a313b9a8bde1ea80a6eae183b76fba46b86558b4
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-OPC_related-Oligodendrocyte/OPC\|1m / Sample Type, Dataset, Time_group, and Cell type.	RPS4X PKP3 SETBP1 SPSB4 RPS27A RPL7	1.21e-06	200	76	6	80cec67b7557465320a847ba959a8a13f7c51566
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Macroglial-Astrocyte\|1m / Sample Type, Dataset, Time_group, and Cell type.	PRSS35 ANXA2 RPS4X RPS27A PAPSS2 RPL7	1.21e-06	200	76	6	4a6efb1b756995d217aacc38639c1bd40f1fd725
ToppCell	moderate-Myeloid-Monocyte-derived_DC\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RPL36A PEBP1 RPS4X DAB2 RPS27A RPL7	1.21e-06	200	76	6	05856f7ae52127adfcfefbc88fd85a86693f2df7
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Macroglial\|1m / Sample Type, Dataset, Time_group, and Cell type.	PRSS35 ANXA2 RPS4X RPS27A PAPSS2 RPL7	1.21e-06	200	76	6	b99249a0de31adab6cc342e276a6b6dfe8d2481c
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-OPC_related\|1m / Sample Type, Dataset, Time_group, and Cell type.	RPS4X PKP3 SETBP1 SPSB4 RPS27A RPL7	1.21e-06	200	76	6	8dafb90b418f91a0fb56c97db06233d3eca358dc
ToppCell	LPS-IL1RA-Endothelial-Mes-Like-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANKAR DAB1 CCDC171 THAP9 PGR	4.99e-06	145	76	5	90ca38c02325c5c637c32efdef634b54cc3cd105
ToppCell	severe_influenza-CD4+_Tcm\|World / disease group, cell group and cell class (v2)	RPL36A PEBP1 RPS4X MCAM RPS27A	8.55e-06	162	76	5	7137990e6e1473665911e39a22092a05ae25ce74
ToppCell	Control-Control-Lymphocyte-T/NK-CD8+_Tcm\|Control / Disease, condition lineage and cell class	RPL36A RPS4X FRMPD1 RPS27A RPL7	9.35e-06	165	76	5	c55f91c4dc70d5021b4efcc795024eb1681d2564
ToppCell	343B-Endothelial_cells-Endothelial-D\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RPL36A ANXA2 RPS4X RPS27A RPL7	1.08e-05	170	76	5	52fdf93c2803fecb2a640ef4e0b257786f3d4cb1
ToppCell	343B-Endothelial_cells-Endothelial-D-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RPL36A ANXA2 RPS4X RPS27A RPL7	1.08e-05	170	76	5	263e98aa1c49493cc262b2608c6582930841cb10
ToppCell	NS-critical-d_16-33-Epithelial-Basal\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANXA2 RPS4X RPS27A PAPSS2 BFSP1	1.18e-05	173	76	5	3d3afc9ab234eaabf5b9bff455406231cd54ded6
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-CD8_TCM\|Multiple_Sclerosis / Disease, Lineage and Cell Type	RPL36A MPZL3 PEBP1 RPS4X RPS27A	1.35e-05	178	76	5	cecfda3625e6f9d9bfe47a147efddb63fa3be6df
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MPZL3 PEBP1 TSPYL2 CPLX1 DAB1	1.42e-05	180	76	5	05f14cd367021891166825a8aac171227e2bcd97
ToppCell	facs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOLH1 DAB2 SPSB4 HABP2 PAPSS2	1.46e-05	181	76	5	bec7076efe94898213a62db72d171d737949977e
ToppCell	facs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOLH1 DAB2 SPSB4 HABP2 PAPSS2	1.46e-05	181	76	5	cf149b30b814cf87c9e923ef502cadf7fe4a3597
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RPL36A RPS4X RPS27A CCDC171 RPL7	1.67e-05	186	76	5	aefb9c186254ba7b02a5ae2bcea7bff2574178f7
ToppCell	droplet-Spleen-nan-3m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL36A ATRX RPS4X RPS27A RPL7	1.67e-05	186	76	5	26f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCell	droplet-Kidney-nan-18m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOLH1 KIF21A DAB2 HABP2 PAPSS2	1.71e-05	187	76	5	236e9857729670e87eed30fad58f49e1f56e4a85
ToppCell	E12.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DAB1 DAB2 SPSB4 PAPSS2 PAPSS1	1.75e-05	188	76	5	9b95730ddd13eb4624321bab3ab4989414977ca3
ToppCell	3'_v3-Lung-Lymphocytic_T_CD8-Trm/em_CD8\|Lung / Manually curated celltypes from each tissue	TNFRSF9 MPZL3 KIF21A TSPYL2 RPS27A	1.85e-05	190	76	5	74638e470ece8016465bbebc1756ffa6d605b25f
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	POLA1 ANKAR DAB2 DAPK1 ZNF891	1.85e-05	190	76	5	63018acb7ad80415e861643162abdc2e55968ee4
ToppCell	367C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	RPL36A RPS4X DAB1 RPS27A RPL7	1.85e-05	190	76	5	b7aafb4393d9b9e3e57411c096afb51dab2b0002
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RPL36A ANXA2 RPS4X DAB2 PAPSS2	1.89e-05	191	76	5	51535232e889db52a9b24e5696b1687e93dd7302
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_2\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	RPS4X DLX1 RPS27A PBX3 RPL7	1.89e-05	191	76	5	509d17d8ee0d028757ce0f2c9b97e5875f06f0ab
ToppCell	Control-Lymphoid-T_Cytotoxic\|Lymphoid / Disease state, Lineage and Cell class	TNFRSF9 RPS4X KIF21A TSPYL2 RPL7	1.89e-05	191	76	5	ff7204f9b645233548cf804cf6fe0c86417be87f
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL36A RPS4X ZDBF2 RPS27A RPL7	1.89e-05	191	76	5	4fcbc214853e115608b3be7b35639247ae41c9dc
ToppCell	Leuk-UTI-Lymphocyte-T_NK-CD4_Naive\|Leuk-UTI / Disease, Lineage and Cell Type	RPL36A RPS4X CPLX1 RPS27A RPL7	1.94e-05	192	76	5	ecdcb210a448495fc141ddc946cca1fbd821ad83
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRSS35 RGS22 CPLX1 LAMA5 DAPK1	1.94e-05	192	76	5	2f539653a20006bef814e6b4acd1023d6fdad5c6
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA2 DAB2 MCAM GPSM2 TNXB	1.94e-05	192	76	5	a42aed9e563f5f4af029b8804c104f11ad227a8f
ToppCell	droplet-Tongue-Unstain-18m-Epithelial-suprabasal_differentiating\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PEBP1 ANXA2 RPS4X RPS27A RPL7	1.94e-05	192	76	5	42b821381fb995fc04589356fd81e8eeeb675757
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRSS35 RPS4X RPS27A PBX3 RPL7	1.99e-05	193	76	5	164cc8d51a67c2df3112338acbb1f93c5f838376
ToppCell	droplet-Tongue-Unstain-18m-Epithelial-basal_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PEBP1 ANXA2 RPS4X RPS27A RPL7	1.99e-05	193	76	5	13282e849b11f48085f0840d112a06e896b32cd7
ToppCell	droplet-Tongue-nan-3m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL36A ATRX RPS4X KIF21A SF3B2	1.99e-05	193	76	5	cba070019db30604ebddb610eedf92e48221ac58
ToppCell	droplet-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL36A ATRX RPS4X KIF21A SF3B2	1.99e-05	193	76	5	07ddb9525b686c31fa7df4286557d1e58f7ead52
ToppCell	critical-Myeloid-Resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RPL36A PEBP1 RPS4X RPS27A RPL7	2.04e-05	194	76	5	0529a990b187a2d875d61e1038821f645ab35a9d
ToppCell	356C-Lymphocytic-CD4_T-cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RPL36A PEBP1 RPS4X RPS27A RPL7	2.04e-05	194	76	5	f51760caee571307851c78897789f6e43bac44ae
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD4-positive,_alpha-beta_T_cell\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RPL36A PEBP1 RPS4X RPS27A RPL7	2.09e-05	195	76	5	4e114f6399863406bd87220dea7fb7dfd08824bd
ToppCell	severe-Lymphocytic-CD4_T_cells_3\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PEBP1 RPS4X ZDBF2 RPS27A RPL7	2.09e-05	195	76	5	90136f65e3e72cf2b2e0a13b48a7c9d60628b396
ToppCell	MS-CD4-memory_CD4\|MS / Condition, Cell_class and T cell subcluster	RPL36A ANXA2 RPS4X RPS27A RPL7	2.09e-05	195	76	5	41ef1304800eda995df88c6057e9835ea31e9125
ToppCell	distal-Hematologic-Basophil/Mast_1-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PEBP1 RPS4X RPS27A RPL7 ADCYAP1	2.09e-05	195	76	5	5aab51a1e6842f2a397926e451133a67467fc614
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS4X PKP3 LAMA5 RPS27A RPL7	2.09e-05	195	76	5	f7a4ce7076148389471678bcc5349df8b72b653e
ToppCell	IIF-Lymphocyte-T_NK-CD4_TCM\|IIF / Disease, Lineage and Cell Type	RPL36A PEBP1 RPS4X RPS27A RPL7	2.09e-05	195	76	5	8f5d469ef00132637154f6e8847ba4d1e4f008cb
ToppCell	mild-Myeloid-mDC\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PEBP1 ANXA2 RPS4X DAB2 RPL7	2.09e-05	195	76	5	c24d286e6c7020ecbc1f460db7685a9a881fc22a
ToppCell	droplet-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL36A RPS4X KIF21A RPS27A RPL7	2.09e-05	195	76	5	a31a8c0e8e666acfc6737fa2c54ebd6f35605520
ToppCell	severe-Myeloid-CD16_Monocytes\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ANXA2 RPS4X DAPK1 PAPSS2 RPL7	2.09e-05	195	76	5	5badcfdeed2fb7453a9c144506ca91c5475cd35f
ToppCell	E12.5-Mesenchymal-mesenchymal_fibroblast\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PRSS35 RPL36A ANXA2 RPS4X RPS27A	2.09e-05	195	76	5	def0a3fb36eec6fbb08e1323baf2b22b28bf751a
ToppCell	hematopoetic_progenitors-CD34+_HSC\|hematopoetic_progenitors / Lineage and Cell class	RPL36A RPS4X TSPYL2 RPS27A RPL7	2.14e-05	196	76	5	d3e20212c15cff0a3c4e23e8b94715b5822a43e2
ToppCell	distal-Hematologic-Basophil/Mast_1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PEBP1 RPS4X RPS27A RPL7 ADCYAP1	2.14e-05	196	76	5	3df0f8fce94bd573f9f9dfeb06d5f68202627740
ToppCell	control-Others-CD34+_GATA2+_cells\|Others / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PEBP1 RPS4X SRP72 CCDC171 RPL7	2.14e-05	196	76	5	25994ca143701c72d2f84a3b6d348fcfa1d26a54
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RPL36A RPS4X DAB2 DAPK1 PAPSS2	2.14e-05	196	76	5	7ce416e1809bfbb39553c28c20125790100a938d
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RPL36A RPS4X KIF21A SETBP1 TSPYL2	2.14e-05	196	76	5	c9fb81a0578db6d278b8582d7b3add6c407e6dcf
ToppCell	15-Trachea-Epithelial-Submucosal_gland\|Trachea / Age, Tissue, Lineage and Cell class	FOLH1 RPS4X RPS27A ADGRL2 RPL7	2.14e-05	196	76	5	e49aa77c8306237c35c625cde1f03e64c06ffc70
ToppCell	normal_Pleural_Fluid-T/NK_cells-Naive_CD4+_T\|T/NK_cells / Location, Cell class and cell subclass	RPL36A PEBP1 RPS4X RPS27A RPL7	2.14e-05	196	76	5	5958caed4172ca478a6d9112d50af9070c850b96
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Macrophage\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RPL36A RPS4X DAB2 DAPK1 PAPSS2	2.14e-05	196	76	5	292da8a0c052917a2f68afee9068b5b8e1544b13
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX RPS4X KIF21A RPS27A RPL7	2.14e-05	196	76	5	d4df86ce289835e76763213641989fde77935a16
ToppCell	moderate-Epithelial-Basal\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RPL36A ANXA2 RPS4X RPS27A RPL7	2.20e-05	197	76	5	6c81bcf6e16ffa7df40e2339feb3362ec3af8837
ToppCell	control-Myeloid-CD16_Monocytes\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ANXA2 RPS4X RPS27A PAPSS2 RPL7	2.20e-05	197	76	5	cdb2866d5a8fbf39847309124479ad49c88852d4
ToppCell	normal_Lung-T/NK_cells-CD4+_Th\|T/NK_cells / Location, Cell class and cell subclass	MPZL3 PEBP1 ANXA2 RPS4X RPS27A	2.20e-05	197	76	5	80b3902ceea242148a1f1707c633f66afedf5183
ToppCell	tumor_Lung-T/NK_cells-CD4+_Th\|T/NK_cells / Location, Cell class and cell subclass	ANXA2 RPS4X RPS27A RPL7 DSE	2.20e-05	197	76	5	0379d67beeba5864b5ffe5d282643204a112754f
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_3\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	RPS4X DLX1 RPS27A PBX3 RPL7	2.20e-05	197	76	5	d77bc37a77546a1f0a508486a38a45e571e4645b
ToppCell	Parenchymal-10x3prime_v2\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	NPHP3 RPL36A RPS4X RPS27A RPL7	2.20e-05	197	76	5	ff9a5d9829f4404eca065d89c25de7b5e5830da3
ToppCell	moderate\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RPL36A PEBP1 RPS4X RPS27A RPL7	2.25e-05	198	76	5	96c3ee2e9a2e06dfe47637f75c70d1e7614f8b85
ToppCell	343B-Endothelial_cells\|343B / Donor, Lineage, Cell class and subclass (all cells)	TGFBR2 SULF2 MCAM ADGRL2 PAPSS2	2.25e-05	198	76	5	fab32347580c7a81ef1fe4fe7b325d9105a947d9
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	PRSS35 ANXA2 KIF21A DAPK1 PAPSS2	2.25e-05	198	76	5	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	mild-Myeloid-CD16_Monocytes\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ANXA2 RPS4X RPS27A PAPSS2 RPL7	2.25e-05	198	76	5	ba97ff6e9d400b53ad013dce54afd7154a0f4fc9
ToppCell	tumor_Lung-Myeloid_cells-Monocytes\|Myeloid_cells / Location, Cell class and cell subclass	RPL36A RPS4X NUMB RPS27A RPL7	2.25e-05	198	76	5	f8f2dc5eeafb4bdbd92134caa1053025c56b71a5
ToppCell	NS-moderate-d_16-33-Epithelial-Basal\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RPL36A ANXA2 RPS4X RPS27A RPL7	2.25e-05	198	76	5	5c52b69d65909b667ef0943e7e04572c9d5b1ba0
ToppCell	VE-CD4-memory_CD4\|VE / Condition, Cell_class and T cell subcluster	RPL36A ANXA2 RPS4X RPS27A RPL7	2.25e-05	198	76	5	ef580576d6669ac7051e8f93fec2f2cd3887e64e
ToppCell	Transverse-T_cell-Th17\|T_cell / Region, Cell class and subclass	RPL36A ANXA2 RPS4X MCAM RPL7	2.25e-05	198	76	5	918068ffd682c896c11d576072bde270630539d9
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RPL36A RPS4X TSPYL2 RPS27A RPL7	2.25e-05	198	76	5	ab17003f5dddc495aa7e1bfb84df66cd2f9113c3
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature2_(2)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RPL36A PEBP1 RPS4X RPS27A RPL7	2.25e-05	198	76	5	df681a2308bf75f4d3cef05d7418aabc96116880
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RPL36A ANXA2 RPS4X RPS27A RPL7	2.25e-05	198	76	5	1f8fc486e0cd77749b61a5b2481a1826f0bcf087
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RPL36A RPS4X TSPYL2 RPS27A RPL7	2.30e-05	199	76	5	55a53949fac7534aa83cfc845131e02032eec5f7
ToppCell	Transverse-T_cell-Th17\|Transverse / Region, Cell class and subclass	RPL36A MPZL3 RPS4X MCAM RPS27A	2.30e-05	199	76	5	640989e048b08d66c5020e032a61ef05f3831034
ToppCell	Caecum-T_cell\|Caecum / Region, Cell class and subclass	RPL36A MPZL3 RPS4X RPS27A RPL7	2.30e-05	199	76	5	4971ba943256f6390dffabf43e45d4e86ce94b46
ToppCell	Transverse-(1)_T_cell-(13)_Th17\|Transverse / shred on region, Cell_type, and subtype	RPL36A MPZL3 RPS4X MCAM RPS27A	2.30e-05	199	76	5	3b17c2704317cac0d641e673563098fd8ca19bd8
ToppCell	NS-critical-LOC-Lymphoid\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RPL36A PEBP1 RPS4X RPS27A RPL7	2.30e-05	199	76	5	e2d0346cc0c45253b1f958e11263f45e09fd38cb
ToppCell	Caecum-(1)_T_cell\|Caecum / shred on region, Cell_type, and subtype	RPL36A MPZL3 RPS4X RPS27A RPL7	2.30e-05	199	76	5	9e8d121550d60091d82f236d7c67361291aaf0e0
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Macroglial-Astrocyte\|5w / Sample Type, Dataset, Time_group, and Cell type.	RPL36A ANXA2 RPS4X RPS27A RPL7	2.36e-05	200	76	5	b64f3f1484de49777efb9b998577ff6bbb6e6861
ToppCell	critical-Myeloid-Monocyte-derived_DC\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PEBP1 ANXA2 RPS4X RPS27A RPL7	2.36e-05	200	76	5	e2d0e635b70f4bc25e1d374d46e63efbb2e2be0f
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-CD4+_T_naive\|Int-URO / Disease, condition lineage and cell class	PEBP1 RPS4X MCAM RPS27A RPL7	2.36e-05	200	76	5	a4b531355e87efd6b69a16eeec8b1ff14c7af750
ToppCell	MS-IIF-Lymphocyte-T/NK-CD4+_T_naive\|IIF / Disease, condition lineage and cell class	RPL36A PEBP1 RPS4X RPS27A RPL7	2.36e-05	200	76	5	fccc4244a87b3e85e8d53285987710aeeb500415
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	FSIP2 RPS4X RPS27A PBX3 RPL7	2.36e-05	200	76	5	ac0e023dbb383bbc46c5cc525431778be8f7ef46
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Macroglial\|5w / Sample Type, Dataset, Time_group, and Cell type.	RPL36A ANXA2 RPS4X RPS27A RPL7	2.36e-05	200	76	5	b09cc353461f2d6b943ecc24db611679378bad2b
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal\|5w / Sample Type, Dataset, Time_group, and Cell type.	RPL36A ANXA2 RPS4X RPS27A RPL7	2.36e-05	200	76	5	fc73565f973c70915e7415f30d7295a63e33d712
ToppCell	severe-CD4+_T_naive\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RPL36A PEBP1 RPS4X RPS27A RPL7	2.36e-05	200	76	5	d9c117c805a95a3c972dd04860902ac1157a210d
Disease	hyperthyroidism (biomarker_via_orthology)	UGT1A1 ANXA2 ANXA2P2	5.14e-05	28	76	3	DOID:7998 (biomarker_via_orthology)
Disease	renal cell carcinoma (biomarker_via_orthology)	ANXA2 ANXA2P2	5.84e-04	14	76	2	DOID:4450 (biomarker_via_orthology)
Disease	MYELODYSPLASTIC SYNDROME	ATRX SETBP1 DAPK1	6.99e-04	67	76	3	C3463824
Disease	Craniofacial Abnormalities	TGFBR2 ATRX SETBP1 DLX1	7.17e-04	156	76	4	C0376634
Disease	Lynch syndrome (is_implicated_in)	TGFBR2 RNASEL	1.74e-03	24	76	2	DOID:3883 (is_implicated_in)
Disease	Squamous cell carcinoma of esophagus	TGFBR2 TNXB ADCYAP1	1.92e-03	95	76	3	C0279626
Disease	brain cancer (implicated_via_orthology)	NUMB GPSM2	2.04e-03	26	76	2	DOID:1319 (implicated_via_orthology)
Disease	Psychotic Disorders	CPLX1 DLX1 ME2	2.28e-03	101	76	3	C0033975
Disease	sleep duration	TGFBR2 MPZL3 ANXA2 DAB1 PBX3	2.45e-03	362	76	5	EFO_0005271
Disease	Hematopoetic Myelodysplasia	ATRX DAPK1	2.54e-03	29	76	2	C2713368

Protein segments in the cluster

Peptide	Gene	Start	Entry
GLQYAAKFIKKRRTK	DAPK1	36	P53355
KKLQVSRHKKFGYGV	TBC1D32	716	Q96NH3
KKTFKGLIRIFRKGV	CCDC171	791	Q6TFL3
ALQKKVRKEYGKCFR	ADGRL2	1086	O95490
LKIRSEFKRKYGKSL	ANXA2	301	P07355
KLLKVETRGGKAFYR	ASMT	71	P46597
FNGKGKKIRKPRTIY	DLX1	121	P56177
LKIRSEFKRKYGKSL	ANXA2P2	301	A6NMY6
RPRKKARKYLYAVGG	IPP	281	Q9Y573
KHFEKKKDIRRGIGY	ANKAR	301	Q7Z5J8
ARFKGDGVKYKAKLI	DAB2	41	P98082
FGNKRIRYKKNIGKF	PBX3	286	P40426
KGLYKRARAGEIKGF	PAPSS2	161	O95340
SAKLLFVNRLKGKKY	GPSM2	441	P81274
VIARYGKVFRGNKVK	FOLH1	201	Q04609
RKDILKRLKKGGYIT	FSIP2	111	Q5CZC0
AVRQGIRDKYGIKKK	CPLX1	61	O14810
AYILEGKKIVGRKKA	FHIP2B	171	Q86V87
RGKFKVASFRKKYEL	PEBP1	146	P30086
GKEYAAKFIKKRRLS	DAPK3	36	O43293
RGYVGEKIKLKCTFK	MPZL3	41	Q6UWV2
SKKNRRAGKRYKFVD	DSE	806	Q9UL01
VKGIKALGKYVDLKR	LAMA5	3091	O15230
KRGYGKINKKRIALT	RPL7	156	P18124
KKGRKKAAYAGGLVL	POLA1	831	P09884
YLKGALKKVVGRVVF	OR1F1	296	O43749
GRKFKKFNKVRVVRA	PGR	636	P06401
AVLGKRYKQRVKNKG	ADCYAP1	156	P18509
KGLYKKARAGEIKGF	PAPSS1	171	O43252
IAERKIKRIYGGFKS	HABP2	306	Q14520
AYGREKKRCKLLGKS	ATRX	1086	P46100
AFKRLNYRKTKLGGK	BRME1	631	Q0VDD7
LIKRFKGEGVRYKAK	DAB1	31	O75553
GGVKKYAKTLRKRRS	FRMPD1	826	Q5SYB0
QISKGFGKLYRKVKE	BFSP1	436	Q12934
KYGLLVKGRKAKIDS	ME2	346	P23368
YSAKKGRGYARKRQK	COL25A1-DT	31	Q6ZST2
TLDKVVRKLKGKYGF	PHKB	316	Q93100
VRKLKGKYGFKRFLR	PHKB	321	Q93100
RGKSLKKRSYFGKLT	IRS4	606	O14654
KVLYGGRKAKELDKV	NYAP1	636	Q6ZVC0
FLYKKGKLPCRRSGK	MCAM	581	P43121
AVKRLKAERKFFKGF	NUMB	61	P49757
VGFYIKQKKTRSKGR	UTP20	476	O75691
AKKRKIEFLRPGYKA	UTP20	2756	O75691
IGKGNYGKVLLAKRK	SGK2	41	Q9HBY8
GKFRKGKRKSKEQRY	GMNC	141	A6NCL1
IKKKGNLYGFALLRR	NPHP3	1061	Q7Z494
YKKGKDSLYAQGKRR	RPL36A	26	P83881
ERFKKFIKGTLGERY	RGS22	416	Q8NE09
LKKKQALRAKYGIRD	LARS1	406	Q9P2J5
KRGLSVRKGKKSREY	PLCL2	891	Q9UPR0
GKVKALKFLYKRGAN	RNASEL	136	Q05823
GKGRFAEVYKAKLKQ	TGFBR2	251	P37173
YKLCKVRKIFVGTKG	RPS4X	121	P62701
RERSYYRGRKKGKKK	SRP72	581	O76094
GRVYVLKFKAGSKRL	ADRM1	91	Q16186
YFDGLRKLIFIKKKR	PKP3	741	Q9Y446
KGKARKLFYKAIVRG	TNRC18	2801	O15417
FKRKYLQGKRGIEKP	SF3B2	506	Q13435
IKAGKAFLRLKRKFI	TSPYL2	231	Q9H2G4
KVFVRKLRKAYGKSE	PES1	86	O00541
FESYGIRRKLKKGAV	THAP9	71	Q9H5L6
YLGVAFRGLKGKKLY	SPSB4	196	Q96A44
RKKYQRKGLTGRVFI	KIF21A	901	Q7Z4S6
AKRALKKAYRLGSQK	TONSL	261	Q96HA7
DYVKGSKKLRVGLLK	PRSS35	176	Q8N3Z0
KKYKFLLYGLLGGKR	TNXB	3511	P22105
SVVKRGRKKLLYIFK	TNFRSF9	211	Q07011
AYGYRKCLGKKGRVK	UGT1A1	511	P22309
RSAFLGRYLKKKKSV	ZDBF2	2241	Q9HCK1
EFGRKKKKYRGKAVG	ZRANB2	126	O95218
KYGGKKRRKDRIQDL	UBN1	111	Q9NPG3
SKRGTIYIGKKRGRK	SETBP1	716	Q9Y6X0
LRLRGGAKKRKKKSY	RPS27A	71	P62979
YKLSLAGRRKKLFKK	SULF2	511	Q8IWU5
GKAFKRISNLTLYKK	ZNF891	326	A8MT65
VIARYGKIFRGNKVK	NAALAD2	191	Q9Y3Q0