Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR5P2 VN1R2 OR5P3 NPBWR1 OR8J3 OR2AK2 OR8D1 DRD1 OR10A7 OR7C1 MAS1 OR5AN1 GPR82 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 GPR153 GPR149 OR5K2 OR10J4 ACKR2 TAS2R39 OR6T1 OR5AP2 OR51H1 OR10A5

1.66e-178849930GO:0004930
GeneOntologyMolecularFunctionolfactory receptor activity

OR5P2 OR5P3 OR8J3 OR2AK2 OR8D1 OR10A7 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 OR5K2 OR10J4 OR6T1 OR5AP2 OR51H1 OR10A5

2.20e-154319921GO:0004984
GeneOntologyMolecularFunctionodorant binding

OR5P2 VN1R2 OR5P3 OR8J3 OR8D1 OR5AN1 OR8J1 OR10J1 OR10Z1 OR5J2 OR5K2 OR10J4 OR5AP2

5.80e-141279913GO:0005549
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR5P2 VN1R2 OR5P3 PLXNA3 NPBWR1 OR8J3 OR2AK2 OR8D1 DRD1 OR10A7 OR7C1 MAS1 OR5AN1 GPR82 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 GPR153 GPR149 OR5K2 OR10J4 ACKR2 TAS2R39 OR6T1 OR5AP2 OR51H1 OR10A5

2.09e-1313539931GO:0004888
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC6A18 BEST1 SCN11A TMEM144 SLC26A3 KCNH8 ABCA12 CFTR SLC19A2 MFSD2B SLC43A3 PKDREJ ABCA9 ABCA8 KCNH4 ANO8 KCNH3 KCNH6 SLCO1C1 SLC16A2 KCNH2 SLC6A20 NIPA2 NIPA1 SERINC5 SLC7A10 KCNT1 ABCC10

1.82e-1211809928GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SLC6A18 BEST1 SCN11A TMEM144 SLC26A3 KCNH8 ABCA12 CFTR SLC19A2 MFSD2B SLC43A3 PKDREJ ABCA9 ABCA8 KCNH4 ANO8 KCNH3 KCNH6 SLCO1C1 SLC16A2 KCNH2 NPC1L1 SLC6A20 NIPA2 NIPA1 SERINC5 SLC7A10 KCNT1 ABCC10

2.45e-1212899929GO:0005215
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC6A18 BEST1 SCN11A SLC26A3 KCNH8 CFTR PKDREJ KCNH4 ANO8 KCNH3 KCNH6 KCNH2 SLC6A20 NIPA2 NIPA1 KCNT1 ABCC10

1.77e-077589917GO:0015318
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC6A18 BEST1 SCN11A SLC26A3 KCNH8 CFTR PKDREJ KCNH4 ANO8 KCNH3 KCNH6 KCNH2 SLC6A20 NIPA2 NIPA1 KCNT1

1.71e-067939916GO:0015075
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

BEST1 SLC26A3 CFTR SLC19A2 SLC43A3 SLCO1C1 SLC16A2 SLC6A20 SERINC5 SLC7A10

1.96e-062939910GO:0008514
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC6A18 SCN11A KCNH8 PKDREJ KCNH4 KCNH3 KCNH6 KCNH2 SLC6A20 NIPA2 NIPA1 KCNT1

3.26e-064659912GO:0046873
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA12 CFTR ABCA9 ABCA8 ABCC10

4.34e-0649995GO:0140359
GeneOntologyMolecularFunctionlipid transporter activity

ABCA12 MFSD2B SLC43A3 ABCA9 ABCA8 ANO8 SLCO1C1 NPC1L1

5.96e-06196998GO:0005319
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC26A3 SLC19A2 SLC43A3 SLCO1C1 SLC16A2 SLC6A20 SERINC5 SLC7A10

8.89e-06207998GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC26A3 SLC19A2 SLC43A3 SLCO1C1 SLC16A2 SLC6A20 SERINC5 SLC7A10

9.21e-06208998GO:0005342
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2 KCNT1

1.17e-05102996GO:0005249
GeneOntologyMolecularFunctionmonoatomic ion channel activity

BEST1 SCN11A KCNH8 CFTR PKDREJ KCNH4 ANO8 KCNH3 KCNH6 KCNH2 KCNT1

1.72e-054599911GO:0005216
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A18 SLC26A3 ABCA12 CFTR MFSD2B ABCA9 ABCA8 SLCO1C1 SLC16A2 SLC6A20 ABCC10

2.45e-054779911GO:0022804
GeneOntologyMolecularFunctionpotassium channel activity

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2 KCNT1

4.25e-05128996GO:0005267
GeneOntologyMolecularFunctiongated channel activity

BEST1 KCNH8 CFTR KCNH4 ANO8 KCNH3 KCNH6 KCNH2 KCNT1

4.25e-05334999GO:0022836
GeneOntologyMolecularFunctionchannel activity

BEST1 SCN11A KCNH8 CFTR PKDREJ KCNH4 ANO8 KCNH3 KCNH6 KCNH2 KCNT1

5.84e-055259911GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

BEST1 SCN11A KCNH8 CFTR PKDREJ KCNH4 ANO8 KCNH3 KCNH6 KCNH2 KCNT1

5.94e-055269911GO:0022803
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC6A18 SCN11A KCNH8 PKDREJ KCNH4 KCNH3 KCNH6 KCNH2 SLC6A20 NIPA2 NIPA1 KCNT1

6.33e-056279912GO:0022890
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC6A18 SCN11A KCNH8 PKDREJ KCNH4 KCNH3 KCNH6 KCNH2 SLC6A20 NIPA2 NIPA1 KCNT1

1.09e-046649912GO:0008324
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2 KCNT1

1.10e-04152996GO:0022843
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC6A18 SLC16A2 SLC6A20 SERINC5 SLC7A10

1.77e-04105995GO:0015171
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2 KCNT1

1.84e-04167996GO:0015079
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC6A18 BEST1 SLC26A3 CFTR ANO8 ABCC10

2.10e-04171996GO:0015103
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA12 CFTR ABCA9 ABCA8 ABCC10

2.10e-04109995GO:0042626
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2 KCNT1

2.93e-04182996GO:0005244
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SCN11A KCNH8 PKDREJ KCNH4 KCNH3 KCNH6 KCNH2 KCNT1

3.08e-04343998GO:0005261
GeneOntologyMolecularFunctionvoltage-gated channel activity

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2 KCNT1

3.11e-04184996GO:0022832
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC6A18 BEST1 SLC26A3 CFTR ANO8

3.97e-04125995GO:0015108
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

BEST1 CFTR ANO8 KCNH6 KCNH2 KCNT1

4.01e-04193996GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

BEST1 CFTR ANO8 KCNH6 KCNH2 KCNT1

4.47e-04197996GO:0022834
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

BEST1 SLC26A3 CFTR

5.28e-0432993GO:0015106
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

SLC43A3 ABCA8 ABCC10

6.33e-0434993GO:0042910
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC19A2 SLC6A20 SERINC5 SLC7A10

7.74e-0483994GO:0015101
GeneOntologyMolecularFunctionthyroid hormone transmembrane transporter activity

SLCO1C1 SLC16A2

8.56e-049992GO:0015349
GeneOntologyMolecularFunctionL-serine transmembrane transporter activity

SERINC5 SLC7A10

8.56e-049992GO:0015194
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC6A18 BEST1 SLC26A3 CFTR ANO8

9.35e-04151995GO:0008509
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

CFTR ABCC10

1.07e-0310992GO:0043225
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC6A18 SLC6A20 SLC7A10

1.10e-0341993GO:0015175
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCA12 CFTR ABCA9 ABCA8 ABCC10

1.94e-03178995GO:0015399
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

BEST1 CFTR ANO8

1.96e-0350993GO:0099095
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCA8 ABCC10

2.45e-0315992GO:0008559
GeneOntologyMolecularFunctionsulfur compound transmembrane transporter activity

SLC26A3 SLC19A2 ABCC10

3.45e-0361993GO:1901682
GeneOntologyMolecularFunctionmagnesium ion transmembrane transporter activity

NIPA2 NIPA1

3.54e-0318992GO:0015095
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A18 SLC26A3 MFSD2B SLCO1C1 SLC16A2 SLC6A20

3.57e-03296996GO:0015291
GeneOntologyMolecularFunctionintracellularly calcium-gated channel activity

BEST1 ANO8

4.36e-0320992GO:0141147
GeneOntologyMolecularFunctionintracellularly calcium-gated chloride channel activity

BEST1 ANO8

4.36e-0320992GO:0005229
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC6A20 SERINC5 SLC7A10

5.29e-0371993GO:0015179
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCA12 SLC43A3 SLCO1C1

5.72e-0373993GO:0170055
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC6A18 SLC6A20

5.75e-0323992GO:0005283
GeneOntologyMolecularFunctioninward rectifier potassium channel activity

KCNH6 KCNH2

8.46e-0328992GO:0005242
GeneOntologyMolecularFunctioncargo receptor activity

CUBN LRP1B ACKR2

8.70e-0385993GO:0038024
GeneOntologyMolecularFunctionchloride channel activity

BEST1 CFTR ANO8

8.99e-0386993GO:0005254
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC6A18 SLC6A20

9.05e-0329992GO:0005416
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLC43A3 SLCO1C1 SLC16A2

1.02e-0290993GO:0008028
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR5P2 OR5P3 BEST1 SCN11A OR8J3 OR2AK2 OR8D1 OR10A7 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 EYS OR5J2 OR1I1 OR10A4 OR5K2 OR10J4 TAS2R39 OR6T1 OR5AP2 OR51H1 OR10A5

2.85e-175829925GO:0050906
GeneOntologyBiologicalProcessdetection of stimulus

OR5P2 OR5P3 BEST1 SCN11A OR8J3 OR2AK2 OR8D1 OR10A7 OR7C1 OR5AN1 OR8J1 OR2B6 PKDREJ OR10J1 OR10Z1 EYS OR5J2 OR1I1 OR10A4 OR5K2 OR10J4 TAS2R39 OR6T1 OR5AP2 OR51H1 OR10A5

4.19e-167229926GO:0051606
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR5P2 OR5P3 OR8J3 OR2AK2 OR8D1 OR10A7 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 OR5K2 OR10J4 TAS2R39 OR6T1 OR5AP2 OR51H1 OR10A5

9.88e-164859922GO:0050907
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR5P2 VN1R2 OR5P3 OR8J3 OR2AK2 OR8D1 OR10A7 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 OR5K2 OR10J4 TAS2R39 OR6T1 OR5AP2 OR51H1 OR10A5

1.03e-155479923GO:0007606
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR5P2 OR5P3 OR8J3 OR2AK2 OR8D1 OR10A7 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 OR5K2 OR10J4 OR6T1 OR5AP2 OR51H1 OR10A5

1.23e-154329921GO:0050911
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR5P2 OR5P3 OR8J3 OR2AK2 OR8D1 OR10A7 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 OR5K2 OR10J4 TAS2R39 OR6T1 OR5AP2 OR51H1 OR10A5

4.87e-155249922GO:0009593
GeneOntologyBiologicalProcesssensory perception of smell

OR5P2 OR5P3 OR8J3 OR2AK2 OR8D1 OR10A7 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 OR5K2 OR10J4 OR6T1 OR5AP2 OR51H1 OR10A5

5.28e-154659921GO:0007608
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR5P2 VN1R2 OR5P3 NPBWR1 SCN11A OR8J3 OR2AK2 OR8D1 DRD1 OR10A7 OR7C1 MAS1 OR5AN1 GPR82 MFSD2B OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 GPR153 GPR149 OR5K2 OR10J4 ACKR2 TAS2R39 OR6T1 OR5AP2 OR51H1 OR10A5

3.01e-1413959932GO:0007186
GeneOntologyBiologicalProcesssensory perception

OR5P2 VN1R2 OR5P3 BEST1 SCN11A OR8J3 OR2AK2 OR8D1 OR10A7 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 EYS OR5J2 OR1I1 OR10A4 OR5K2 OR10J4 TAS2R39 OR6T1 OR5AP2 OR51H1 OR10A5

4.08e-1210729926GO:0007600
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC6A18 BEST1 SCN11A SLC26A3 DRD1 KCNH8 CFTR PKDREJ KCNH4 ANO8 KCNH3 KCNH6 KCNH2 SLC6A20 NIPA2 NIPA1 KCNT1 ABCC10

5.30e-0611159918GO:0034220
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC6A18 BEST1 SCN11A SLC26A3 DRD1 KCNH8 CFTR PKDREJ KCNH4 ANO8 KCNH3 KCNH6 KCNH2 SLC6A20 NIPA2 NIPA1 KCNT1

6.37e-0610179917GO:0098660
GeneOntologyBiologicalProcessmembrane lipid metabolic process

ABCA12 MFSD2B ST8SIA1 PIGZ ABCA8 B4GALT5 AGMO HACD1

1.47e-05229998GO:0006643
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC6A18 BEST1 SCN11A SLC26A3 DRD1 KCNH8 CFTR PKDREJ KCNH4 ANO8 KCNH3 KCNH6 SLCO1C1 KCNH2 SLC6A20 NIPA2 NIPA1 KCNT1 ABCC10

2.51e-0513749919GO:0006811
GeneOntologyBiologicalProcesscarboxylic acid transport

BEST1 SLC26A3 SLC19A2 SLC43A3 SLCO1C1 SLC16A2 SLC6A20 SERINC5 SLC7A10 ABCC10

2.79e-054109910GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

BEST1 SLC26A3 SLC19A2 SLC43A3 SLCO1C1 SLC16A2 SLC6A20 SERINC5 SLC7A10 ABCC10

2.90e-054129910GO:0015849
GeneOntologyBiologicalProcessorganic anion transport

BEST1 SLC26A3 CFTR SLC19A2 SLC43A3 SLCO1C1 SLC16A2 SLC6A20 SERINC5 SLC7A10 ABCC10

3.67e-055159911GO:0015711
GeneOntologyBiologicalProcessmetal ion transport

SLC6A18 BEST1 SCN11A DRD1 KCNH8 CFTR PKDREJ KCNH4 KCNH3 KCNH6 KCNH2 SLC6A20 NIPA2 NIPA1 KCNT1

8.18e-0510009915GO:0030001
GeneOntologyBiologicalProcessmembrane lipid biosynthetic process

MFSD2B ST8SIA1 PIGZ ABCA8 B4GALT5 HACD1

1.11e-04157996GO:0046467
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC6A18 SCN11A DRD1 KCNH8 CFTR PKDREJ KCNH4 KCNH3 KCNH6 KCNH2 SLC6A20 NIPA2 NIPA1 KCNT1

1.27e-049229914GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC6A18 SCN11A DRD1 KCNH8 CFTR PKDREJ KCNH4 KCNH3 KCNH6 KCNH2 SLC6A20 NIPA2 NIPA1 KCNT1

1.59e-049429914GO:0098655
GeneOntologyBiologicalProcessneutral amino acid transport

SLC6A18 SLC6A20 SERINC5 SLC7A10

1.98e-0460994GO:0015804
GeneOntologyBiologicalProcesssphingolipid metabolic process

ABCA12 MFSD2B ST8SIA1 ABCA8 B4GALT5 HACD1

2.06e-04176996GO:0006665
GeneOntologyBiologicalProcesssphingolipid biosynthetic process

MFSD2B ST8SIA1 ABCA8 B4GALT5 HACD1

2.52e-04117995GO:0030148
GeneOntologyBiologicalProcesspotassium ion transport

DRD1 KCNH8 KCNH4 KCNH3 KCNH6 KCNH2 KCNT1

3.40e-04272997GO:0006813
GeneOntologyBiologicalProcessregulation of membrane potential

SCN11A SLC26A3 DRD1 KCNH8 CFTR KCNH4 KCNH3 KCNH6 KCNH2 KCNT1

3.54e-045599910GO:0042391
GeneOntologyBiologicalProcessamino acid transport

SLC6A18 BEST1 SLC16A2 SLC6A20 SERINC5 SLC7A10

3.57e-04195996GO:0006865
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC6A18 BEST1 SCN11A DRD1 KCNH8 CFTR PKDREJ KCNH4 KCNH3 KCNH6 KCNH2 SLC6A20 NIPA2 NIPA1 KCNT1

3.99e-0411579915GO:0006812
GeneOntologyBiologicalProcessintracellular pH elevation

SLC26A3 CFTR

6.27e-048992GO:0051454
GeneOntologyBiologicalProcesslipid transport

ABCA12 CFTR MFSD2B SLC43A3 ABCA9 ABCA8 SLCO1C1 NPC1L1 ABCC10

7.35e-04506999GO:0006869
GeneOntologyBiologicalProcessbicarbonate transport

BEST1 SLC26A3 CFTR

8.01e-0438993GO:0015701
GeneOntologyBiologicalProcessL-serine transport

SERINC5 SLC7A10

8.03e-049992GO:0015825
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

BEST1 SLC26A3 CFTR ANO8 ABCC10

8.59e-04153995GO:0098656
GeneOntologyBiologicalProcesspotassium ion transmembrane transport

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2 KCNT1

8.90e-04232996GO:0071805
GeneOntologyCellularComponentbrush border membrane

SLC6A18 SLC26A3 CUBN NPC1L1 SLC6A20

4.89e-05831005GO:0031526
GeneOntologyCellularComponentinterphotoreceptor matrix

EYS VCAN

3.36e-0461002GO:0033165
GeneOntologyCellularComponentmonoatomic ion channel complex

BEST1 SCN11A KCNH8 CFTR KCNH4 KCNH3 KCNH6 KCNH2

4.65e-043781008GO:0034702
GeneOntologyCellularComponentbrush border

SLC6A18 SLC26A3 CUBN NPC1L1 SLC6A20

8.23e-041521005GO:0005903
DomainGPCR_Rhodpsn_7TM

OR5P2 VN1R2 OR5P3 NPBWR1 OR8J3 OR2AK2 OR8D1 DRD1 OR10A7 OR7C1 MAS1 OR5AN1 GPR82 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 GPR153 GPR149 OR5K2 ACKR2 OR6T1 OR5AP2 OR10A5

3.94e-176709727IPR017452
DomainG_PROTEIN_RECEP_F1_1

OR5P2 VN1R2 OR5P3 NPBWR1 OR8J3 OR2AK2 OR8D1 DRD1 OR10A7 OR7C1 MAS1 OR5AN1 GPR82 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 GPR153 GPR149 OR5K2 ACKR2 OR6T1 OR5AP2 OR10A5

6.86e-176859727PS00237
DomainG_PROTEIN_RECEP_F1_2

OR5P2 VN1R2 OR5P3 NPBWR1 OR8J3 OR2AK2 OR8D1 DRD1 OR10A7 OR7C1 MAS1 OR5AN1 GPR82 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 GPR153 GPR149 OR5K2 ACKR2 OR6T1 OR5AP2 OR10A5

8.53e-176919727PS50262
DomainGPCR_Rhodpsn

OR5P2 VN1R2 OR5P3 NPBWR1 OR8J3 OR2AK2 OR8D1 DRD1 OR10A7 OR7C1 MAS1 OR5AN1 GPR82 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 GPR153 GPR149 OR5K2 ACKR2 OR6T1 OR5AP2 OR10A5

8.84e-176929727IPR000276
Domain7tm_1

OR5P2 OR5P3 NPBWR1 OR8J3 OR2AK2 OR8D1 DRD1 OR10A7 OR7C1 MAS1 OR5AN1 GPR82 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 GPR153 GPR149 OR5K2 ACKR2 OR6T1 OR5AP2 OR10A5

5.39e-166779726PF00001
DomainOlfact_rcpt

OR5P2 OR5P3 OR8J3 OR2AK2 OR8D1 OR10A7 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 OR5K2 OR6T1 OR5AP2 OR10A5

1.39e-133939719IPR000725
DomainPAS_9

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

8.41e-1010975PF13426
DomainK_chnl_volt-dep_EAG/ELK/ERG

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

6.57e-0914975IPR003938
DomainPAS-assoc_C

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

1.34e-0724975IPR000700
DomainK_chnl_volt-dep_ELK

KCNH8 KCNH4 KCNH3

1.36e-073973IPR003950
DomainPAC

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

2.05e-0726975IPR001610
DomainPAC

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

2.05e-0726975SM00086
DomainPAC

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

2.05e-0726975PS50113
DomainCNMP_BINDING_1

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

6.14e-0732975PS00888
DomainCNMP_BINDING_2

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

6.14e-0732975PS00889
DomaincNMP

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

8.41e-0734975SM00100
DomainPAS

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

8.41e-0734975IPR000014
DomainPAS

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

8.41e-0734975PS50112
DomaincNMP_binding

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

8.41e-0734975PF00027
DomaincNMP-bd_dom

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

9.77e-0735975IPR000595
DomainCNMP_BINDING_3

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

9.77e-0735975PS50042
DomaincNMP-bd-like

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

1.49e-0638975IPR018490
DomainABC_tran

ABCA12 CFTR ABCA9 ABCA8 ABCC10

4.89e-0648975PF00005
Domain-

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

4.89e-06489752.60.120.10
DomainABC_TRANSPORTER_2

ABCA12 CFTR ABCA9 ABCA8 ABCC10

4.89e-0648975PS50893
DomainABC_TRANSPORTER_1

ABCA12 CFTR ABCA9 ABCA8 ABCC10

5.42e-0649975PS00211
DomainABC_transporter-like

ABCA12 CFTR ABCA9 ABCA8 ABCC10

6.00e-0650975IPR003439
DomainRmlC-like_jellyroll

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

6.62e-0651975IPR014710
DomainIon_trans_dom

SCN11A KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

2.85e-05114976IPR005821
DomainIon_trans

SCN11A KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

2.85e-05114976PF00520
DomainABC_A

ABCA12 ABCA9 ABCA8

2.89e-0512973IPR026082
DomainK_chnl_volt-dep_ERG

KCNH6 KCNH2

7.98e-053972IPR003967
DomainPAS_fold_3

KCNH8 KCNH4 KCNH3

2.23e-0423973IPR013655
DomainPAS_3

KCNH8 KCNH4 KCNH3

2.23e-0423973PF08447
DomainNa/ntran_symport_orphan

SLC6A18 SLC6A20

2.64e-045972IPR002438
DomainMg_trans_NIPA

NIPA2 NIPA1

3.95e-046972IPR008521
DomainMg_trans_NIPA

NIPA2 NIPA1

3.95e-046972PF05653
DomainBax_inhibitor_1-related

GRINA TMBIM4

3.95e-046972IPR006214
DomainPAS

KCNH4 KCNH3 KCNH2

6.04e-0432973SM00091
DomainMFS_dom

SLC19A2 MFSD2B SLC43A3 SLCO1C1 SLC16A2

6.70e-04134975IPR020846
DomainAAA+_ATPase

ABCA12 CFTR ABCA9 ABCA8 ABCC10

9.27e-04144975IPR003593
DomainAAA

ABCA12 CFTR ABCA9 ABCA8 ABCC10

9.27e-04144975SM00382
DomainABC_transporter_CS

ABCA12 CFTR ABCC10

1.35e-0342973IPR017871
DomainEGF_3

CUBN LRP1B EYS TENM3 VCAN C8B

1.42e-03235976PS50026
DomainEGF_Ca-bd_CS

CUBN LRP1B EYS VCAN

1.64e-0397974IPR018097
DomainEGF_CA

CUBN LRP1B EYS VCAN

1.77e-0399974PS01187
DomainASX_HYDROXYL

CUBN LRP1B EYS VCAN

1.83e-03100974PS00010
DomainEGF-like_dom

CUBN LRP1B EYS TENM3 VCAN C8B

1.90e-03249976IPR000742
DomainEGF_1

CUBN LRP1B EYS TENM3 VCAN C8B

2.14e-03255976PS00022
DomainEGF-type_Asp/Asn_hydroxyl_site

CUBN LRP1B EYS VCAN

2.27e-03106974IPR000152
DomainEGF-like_CS

CUBN LRP1B EYS TENM3 VCAN C8B

2.41e-03261976IPR013032
DomainEGF_2

CUBN LRP1B EYS TENM3 VCAN C8B

2.59e-03265976PS01186
DomainEGF_CA

CUBN LRP1B EYS VCAN

3.76e-03122974SM00179
DomainNA_NEUROTRAN_SYMP_2

SLC6A18 SLC6A20

3.87e-0318972PS00754
DomainEGF-like_Ca-bd_dom

CUBN LRP1B EYS VCAN

3.99e-03124974IPR001881
DomainEGF

CUBN LRP1B EYS VCAN

4.22e-03126974PF00008
DomainSNF

SLC6A18 SLC6A20

4.31e-0319972PF00209
DomainNA_NEUROTRAN_SYMP_1

SLC6A18 SLC6A20

4.31e-0319972PS00610
DomainNA_NEUROTRAN_SYMP_3

SLC6A18 SLC6A20

4.31e-0319972PS50267
DomainNa/ntran_symport

SLC6A18 SLC6A20

4.31e-0319972IPR000175
DomainABC_membrane

CFTR ABCC10

6.84e-0324972PF00664
DomainPAS

KCNH6 KCNH2

7.41e-0325972PF00989
DomainPAS_fold

KCNH6 KCNH2

7.41e-0325972IPR013767
DomainEGF

CUBN LRP1B EYS TENM3 VCAN

7.63e-03235975SM00181
DomainABC_TM1F

CFTR ABCC10

9.24e-0328972PS50929
DomainABC1_TM_dom

CFTR ABCC10

9.24e-0328972IPR011527
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR5P2 OR5P3 OR8J3 OR2AK2 OR8D1 OR10A7 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 OR5K2 OR10J4 OR6T1 OR5AP2 OR51H1 OR10A5

7.27e-154177921M4072
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR5P2 OR5P3 OR8J3 OR2AK2 OR8D1 OR10A7 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 OR5K2 OR6T1 OR5AP2 OR10A5

2.98e-133897919M14091
PathwayREACTOME_SENSORY_PERCEPTION

OR5P2 OR5P3 OR8J3 OR2AK2 OR8D1 OR10A7 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 OR5K2 OR10J4 TAS2R39 OR6T1 OR5AP2 OR51H1 OR10A5

3.03e-126367922M41834
PathwayWP_GPCRS_ODORANT

OR5P2 GPR137 OR5P3 GPR82 OR2B6 OR5J2 GPR153 GPR149 TAS2R39 OR5AP2

1.64e-081577910MM15872
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC6A18 BEST1 SLC26A3 ABCA12 CFTR HMOX2 CUBN ABCA9 ABCA8 ANO8 SLCO1C1 SLC16A2 SLC6A20 NIPA2 NIPA1 SLC7A10 ABCC10

5.03e-077367917M27287
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC6A18 BEST1 SLC26A3 ABCA12 CFTR HMOX2 ABCA9 ABCA8 ANO8 SLCO1C1 SLC16A2 SLC6A20 NIPA2 NIPA1 SLC7A10 ABCC10

9.23e-076817916MM14985
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

NPBWR1 DRD1 OR7C1 MAS1 OR2B6 OR10J1 OR1I1 OR10A4 ACKR2 OR10A5

1.80e-062607910M39397
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

3.11e-0641795MM14546
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

3.96e-0643795M1056
PathwayKEGG_ABC_TRANSPORTERS

ABCA12 CFTR ABCA9 ABCA8 ABCC10

4.45e-0644795M11911
PathwayREACTOME_POTASSIUM_CHANNELS

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

2.20e-0498795MM14545
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ABCA12 CFTR ABCA9 ABCA8 ABCC10

2.31e-0499795MM14986
PathwayREACTOME_POTASSIUM_CHANNELS

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

2.77e-04103795M1073
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ABCA12 CFTR ABCA9 ABCA8 ABCC10

2.77e-04103795M758
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

OR5P3 OR8D1 MAS1 OR10A4 ACKR2 OR10A5

6.09e-04186796MM15994
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC6A18 SLC6A20 SLC7A10

7.47e-0432793MM14957
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC6A18 SLC6A20 SLC7A10

8.19e-0433793M188
PathwayWP_15Q112_COPY_NUMBER_VARIATION_SYNDROME

NIPA2 NIPA1

1.09e-039792M39879
PathwayREACTOME_TRANSPORT_OF_ORGANIC_ANIONS

SLCO1C1 SLC16A2

1.65e-0311792M930
PathwayREACTOME_TRANSPORT_OF_ORGANIC_ANIONS

SLCO1C1 SLC16A2

1.97e-0312792MM15476
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A18 SLC26A3 SLCO1C1 SLC16A2 SLC6A20 SLC7A10

2.16e-03238796MM15076
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR5P2 OR5P3 OR8J3 OR2AK2 OR8D1 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 OR5K2 OR5AP2 OR51H1 OR10A5

6.29e-183401001811875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR5P2 OR5P3 OR8J3 OR2AK2 OR8D1 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 OR5K2 OR5AP2 OR51H1 OR10A5

6.29e-183401001811802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR5P2 OR5P3 OR8J3 OR2AK2 OR8D1 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 OR5K2 OR5AP2 OR51H1 OR10A5

7.35e-183431001832295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR5P2 OR5P3 OR8J3 OR2AK2 OR8D1 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR1I1 OR10A4 OR5K2 OR5AP2 OR51H1 OR10A5

8.57e-183461001814611657
Pubmed

The human olfactory receptor gene family.

OR5P2 OR5P3 OR8J3 OR2AK2 OR8D1 OR10A7 OR7C1 OR5AN1 OR8J1 OR2B6 OR10J1 OR10Z1 OR5J2 OR10A4 OR5K2 OR6T1 OR51H1 OR10A5

2.03e-145411001814983052
Pubmed

Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate.

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

4.42e-1110100526503718
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR5P3 OR8J3 OR10A7 OR7C1 OR8J1 OR10J1 OR1I1 OR10A4 OR10J4 OR10A5

8.43e-102191001012213199
Pubmed

Mouse orthologs of human olfactory-like receptors expressed in the tongue.

OR5P2 OR8D1 OR10A4 OR10A5

9.61e-106100416859840
Pubmed

New GPCRs from a human lingual cDNA library.

OR5P2 OR5P3 OR8D1 OR10A4 OR10A5

1.07e-0917100511705801
Pubmed

Odorant and vomeronasal receptor genes in two mouse genome assemblies.

OR5P2 OR8J3 OR2AK2 OR7C1 OR5AN1 OR8J1 OR1I1

2.02e-0974100715081110
Pubmed

Distribution and functional properties of human KCNH8 (Elk1) potassium channels.

KCNH8 KCNH4 KCNH3

2.31e-083100312890647
Pubmed

International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

1.08e-0740100516382104
Pubmed

ABC gene expression profiles have clinical importance and possibly form a new hallmark of cancer.

ABCA12 CFTR ABCA8

2.30e-075100328468577
Pubmed

The G protein-coupled receptor repertoires of human and mouse.

GPR137 DRD1 GPR82 GPR153 GPR149

3.38e-0679100512679517
Pubmed

Expression of the thyroid hormone transporters monocarboxylate transporter-8 (SLC16A2) and organic ion transporter-14 (SLCO1C1) at the blood-brain barrier.

SLCO1C1 SLC16A2

8.18e-062100218687783
Pubmed

Transporters MCT8 and OATP1C1 maintain murine brain thyroid hormone homeostasis.

SLCO1C1 SLC16A2

8.18e-062100224691440
Pubmed

Minireview: Pathophysiological importance of thyroid hormone transporters.

SLCO1C1 SLC16A2

8.18e-062100219179441
Pubmed

Absence of Both Thyroid Hormone Transporters MCT8 and OATP1C1 Impairs Neural Stem Cell Fate in the Adult Mouse Subventricular Zone.

SLCO1C1 SLC16A2

8.18e-062100233450189
Pubmed

A missense mutation in SLC26A3 is associated with human male subfertility and impaired activation of CFTR.

SLC26A3 CFTR

8.18e-062100229079751
Pubmed

The anion exchanger slc26a3 regulates colonic mucus expansion during steady state and in response to prostaglandin E2, while Cftr regulates de novo mucus release in response to carbamylcholine.

SLC26A3 CFTR

8.18e-062100238829391
Pubmed

New ether-à-go-go K(+) channel family members localized in human telencephalon.

KCNH4 KCNH3

8.18e-062100210455180
Pubmed

Proteome Analysis of Thyroid Hormone Transporter Mct8/Oatp1c1-Deficient Mice Reveals Novel Dysregulated Target Molecules Involved in Locomotor Function.

SLCO1C1 SLC16A2

8.18e-062100237887331
Pubmed

TRIAC Treatment Improves Impaired Brain Network Function and White Matter Loss in Thyroid Hormone Transporter Mct8/Oatp1c1 Deficient Mice.

SLCO1C1 SLC16A2

8.18e-062100236555189
Pubmed

Parallel regulation of thyroid hormone transporters OATP1c1 and MCT8 during and after endotoxemia at the blood-brain barrier of male rodents.

SLCO1C1 SLC16A2

8.18e-062100225594699
Pubmed

Thyroid Hormone Transporters MCT8 and OATP1C1 Are Expressed in Pyramidal Neurons and Interneurons in the Adult Motor Cortex of Human and Macaque Brain.

SLCO1C1 SLC16A2

8.18e-062100236834621
Pubmed

Kv12-encoded K+ channels drive the day-night switch in the repetitive firing rates of SCN neurons.

KCNH8 KCNH3

8.18e-062100237516908
Pubmed

Triac Treatment Prevents Neurodevelopmental and Locomotor Impairments in Thyroid Hormone Transporter Mct8/Oatp1c1 Deficient Mice.

SLCO1C1 SLC16A2

8.18e-062100236834863
Pubmed

Thyroid Hormone Transporters MCT8 and OATP1C1 Are Expressed in Projection Neurons and Interneurons of Basal Ganglia and Motor Thalamus in the Adult Human and Macaque Brains.

SLCO1C1 SLC16A2

8.18e-062100237298594
Pubmed

Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.

SLCO1C1 SLC16A2

8.18e-062100236270613
Pubmed

cAMP Stimulates SLC26A3 Activity in Human Colon by a CFTR-Dependent Mechanism That Does Not Require CFTR Activity.

SLC26A3 CFTR

8.18e-062100230659943
Pubmed

Functional analysis of a mouse brain Elk-type K+ channel.

KCNH3 KCNH2

8.18e-062100210191308
Pubmed

Klotho sensitivity of the hERG channel.

KL KCNH2

8.18e-062100223603386
Pubmed

The Thyroid Hormone Transporter MCT10 Is a Novel Regulator of Trabecular Bone Mass and Bone Turnover in Male Mice.

SLCO1C1 SLC16A2

2.45e-053100234669927
Pubmed

Developmentally regulated expression of the mouse homologues of the potassium channel encoding genes m-erg1, m-erg2 and m-erg3.

KCNH6 KCNH2

2.45e-053100214643686
Pubmed

Brain Gene Expression in Systemic Hypothyroidism and Mouse Models of MCT8 Deficiency: The Mct8-Oatp1c1-Dio2 Triad.

SLCO1C1 SLC16A2

2.45e-053100233307956
Pubmed

Luminal kidney and intestine SLC6 amino acid transporters of B0AT-cluster and their tissue distribution in Mus musculus.

SLC6A18 SLC6A20

2.45e-053100216174864
Pubmed

Thyroid Hormone Transporters MCT8 and OATP1C1 Control Skeletal Muscle Regeneration.

SLCO1C1 SLC16A2

2.45e-053100229706500
Pubmed

Deletion of Slc26a6 alters the stoichiometry of apical Cl-/HCO-3 exchange in mouse pancreatic duct.

SLC26A3 CFTR

2.45e-053100222895259
Pubmed

Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome.

KCNH6 KCNH2

2.45e-053100235818223
Pubmed

After Intestinal Transplantation Kidney Function Is Impaired by Downregulation of Epithelial Ion Transporters in the Ileum.

SLC26A3 CFTR

2.45e-053100227109987
Pubmed

HERG K(+) currents in human prolactin-secreting adenoma cells.

KCNH6 KCNH2

2.45e-053100212634931
Pubmed

Native and recombinant Slc26a3 (downregulated in adenoma, Dra) do not exhibit properties of 2Cl-/1HCO3- exchange.

SLC26A3 CFTR

2.45e-053100221068358
Pubmed

Functional activity of Pat-1 (Slc26a6) Cl(−)/HCO₃(−) exchange in the lower villus epithelium of murine duodenum.

SLC26A3 CFTR

2.45e-053100220969732
Pubmed

Expression of SLC26A3, CFTR and NHE3 in the human male reproductive tract: role in male subfertility caused by congenital chloride diarrhoea.

SLC26A3 CFTR

2.45e-053100216421216
Pubmed

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.

ABCA12 ABCA9 ABCC10

3.41e-052210038894702
Pubmed

Expression of 4 genes between chromosome 15 breakpoints 1 and 2 and behavioral outcomes in Prader-Willi syndrome.

NIPA2 NIPA1

4.89e-054100216982806
Pubmed

Acute digoxin loading reduces ABCA8A mRNA expression in the mouse liver.

ABCA9 ABCA8

4.89e-054100216445568
Pubmed

The switch of intestinal Slc26 exchangers from anion absorptive to HCOFormula secretory mode is dependent on CFTR anion channel function.

SLC26A3 CFTR

4.89e-054100220164375
Pubmed

Participation of the Cl-/HCO(3)- exchangers SLC26A3 and SLC26A6, the Cl- channel CFTR, and the regulatory factor SLC9A3R1 in mouse sperm capacitation.

SLC26A3 CFTR

4.89e-054100221976599
Pubmed

The down regulated in adenoma (dra) gene product binds to the second PDZ domain of the NHE3 kinase A regulatory protein (E3KARP), potentially linking intestinal Cl-/HCO3- exchange to Na+/H+ exchange.

SLC26A3 CFTR

4.89e-054100212369822
Pubmed

Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman syndromes deletion region that have undergone evolutionary transposition mediated by flanking duplicons.

NIPA2 NIPA1

4.89e-054100214508708
Pubmed

Role of down-regulated in adenoma anion exchanger in HCO3- secretion across murine duodenum.

SLC26A3 CFTR

4.89e-054100219121635
Pubmed

CFTR and TMEM16A are separate but functionally related Cl- channels.

CFTR ANO8

4.89e-054100222178883
Pubmed

Essential role for collectrin in renal amino acid transport.

SLC6A18 SLC6A20

4.89e-054100217167413
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

SCN11A KCNH8 KCNH3 KCNH6 KCNH2

5.27e-05139100516985003
Pubmed

Sequence-structure based phylogeny of GPCR Class A Rhodopsin receptors.

GPR153 GPR149

8.14e-055100224503482
Pubmed

A contextual model for axonal sorting into glomeruli in the mouse olfactory system.

OR10A4 OR10A5

8.14e-055100215186781
Pubmed

Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.

ABCA9 ABCA8

8.14e-055100212532264
Pubmed

Amino acid transport across mammalian intestinal and renal epithelia.

SLC6A18 SLC6A20 SLC7A10

9.78e-0531100318195088
Pubmed

Comparative genomics and function analysis on BI1 family.

GRINA TMBIM4

1.22e-046100218440869
Pubmed

Linear correlation between the number of olfactory sensory neurons expressing a given mouse odorant receptor gene and the total volume of the corresponding glomeruli in the olfactory bulb.

OR10A4 OR10A5

1.22e-046100226100963
Pubmed

The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA²⁺-filling state.

GRINA TMBIM4

1.22e-046100225764978
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

GPR137 TMEM144 HMOX2 GRINA ANO8 NIPA2 NIPA1 SERINC5 HERPUD1

1.86e-04697100928298427
Pubmed

Cloning, gene structure and genomic localization of an orphan transporter from mouse kidney with six alternatively-spliced isoforms.

SLC6A18 SLC6A20

2.27e-04810029932288
Pubmed

Genomic analysis of orthologous mouse and human olfactory receptor loci.

OR10A4 OR10A5

2.91e-049100211416212
Pubmed

Sensitivity-dependent hierarchical receptor codes for odors.

OR5AN1 OR10A4

2.91e-049100212588732
Pubmed

The expression of thyroid hormone transporters in the human fetal cerebral cortex during early development and in N-Tera-2 neurodifferentiation.

SLCO1C1 SLC16A2

2.91e-049100221486766
Pubmed

D1/NMDA receptors and concurrent methamphetamine+ HIV-1 Tat neurotoxicity.

DRD1 GRINA

2.91e-049100222552781
Pubmed

The Zonal Organization of Odorant Receptor Gene Choice in the Main Olfactory Epithelium of the Mouse.

OR10A4 OR10A5

2.91e-049100232209480
Pubmed

Developmental and cell type-specific expression of thyroid hormone transporters in the mouse brain and in primary brain cells.

SLCO1C1 SLC16A2

2.91e-049100221264952
Pubmed

The human ATP-binding cassette (ABC) transporter superfamily.

ABCA12 ABCA9

3.63e-0410100211435397
Pubmed

Developmental and cell-specific expression of thyroid hormone transporters in the mouse cochlea.

SLCO1C1 SLC16A2

3.63e-0410100221878515
Pubmed

Maternal thyroid hormone is required for parvalbumin neurone development in the anterior hypothalamic area.

SLCO1C1 SLC16A2

3.63e-0410100229377458
Pubmed

Supersensitive detection and discrimination of enantiomers by dorsal olfactory receptors: evidence for hierarchical odour coding.

OR5AN1 OR10A4

4.43e-0411100226361056
Pubmed

Thyroid Hormone Transporter Deficiency in Mice Impacts Multiple Stages of GABAergic Interneuron Development.

SLCO1C1 SLC16A2

6.25e-0413100234339499
Pubmed

Screening of the interaction between xenobiotic transporters and PDZ proteins.

CFTR SLCO1C1

8.39e-0415100215553237
Pubmed

Neuronal 3',3,5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan-Herndon-Dudley syndrome.

SLCO1C1 SLC16A2

1.08e-0317100219641107
Pubmed

Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS.

XPNPEP2 CUBN

1.08e-0317100221082674
Pubmed

Changes in thyroid status during perinatal development of MCT8-deficient male mice.

SLCO1C1 SLC16A2

1.22e-0318100223696569
Pubmed

Sequential arrival and graded secretion of Sema3F by olfactory neuron axons specify map topography at the bulb.

PLXNA3 OR10A4

1.22e-0318100220550939
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

PLXNA3 KCNH8 LRP1B KCNH4 KCNH3 KCNH6 KCNH2 HACD1

1.24e-03730100834857952
Pubmed

The repertoire of solute carriers of family 6: identification of new human and rodent genes.

SLC6A18 SLC6A20

1.66e-0321100216125675
Pubmed

Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.

PLXNA3 XPNPEP2 KCNH6

1.86e-0384100315203218
Pubmed

Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus.

ABCA8 ABCC10

1.99e-0323100210708515
Pubmed

Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.

OR10J1 OR5AP2

1.99e-0323100217903294
Pubmed

Comparative FISH mapping of mouse and rat homologues of twenty-five human X-linked genes.

PLXNA3 PHKA2

2.17e-032410029730605
Pubmed

Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice†.

SLC26A3 CFTR

2.17e-0324100237471646
Pubmed

Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

OR8D1 OR7C1

2.17e-032410029119360
Pubmed

Expression of members of the putative olfactory receptor gene family in mammalian germ cells.

OR10J1 OR5J2

2.35e-032510021370859
Pubmed

Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis.

KCNH6 KCNH2

2.54e-0326100231138815
Pubmed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

SLC26A3 LRP1B EYS TENM3

2.66e-03199100423382691
InteractionKCNH4 interactions

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

7.63e-1012825int:KCNH4
InteractionKCNH6 interactions

KCNH4 KCNH6

1.64e-052822int:KCNH6
CytobandEnsembl 112 genes in cytogenetic band chr11q12

BEST1 OR8J3 OR5AN1 OR8J1 SLC43A3 OR5J2 OR5AP2

1.12e-053451007chr11q12
Cytoband11p15.4

OR5P2 OR5P3 OR10A4 OR51H1 OR10A5

8.03e-05200100511p15.4
Cytoband11q12.1

OR8J3 OR5AN1 OR8J1 OR5AP2

4.40e-04161100411q12.1
GeneFamilyOlfactory receptors, family 10

OR10A7 OR10J1 OR10Z1 OR10A4 OR10J4 OR10A5

2.64e-0766736157
GeneFamilyPotassium voltage-gated channels

KCNH8 KCNH4 KCNH3 KCNH6 KCNH2

5.50e-0740735274
GeneFamilyOlfactory receptors, family 5

OR5P2 OR5P3 OR5AN1 OR5J2 OR5K2 OR5AP2

6.00e-06112736152
GeneFamilyATP binding cassette subfamily A

ABCA12 ABCA9 ABCA8

2.23e-0514733805
GeneFamilySolute carriers

SLC6A18 SLC26A3 SLC19A2 SLC43A3 SLCO1C1 SLC16A2 SLC6A20 SLC7A10

1.88e-04395738752
GeneFamilyTransmembrane BAX inhibitor motif containing

GRINA TMBIM4

2.39e-0467321215
GeneFamilyG protein-coupled receptors, Class A orphans

MAS1 GPR82 GPR153 GPR149

2.78e-0478734262
GeneFamilyOlfactory receptors, family 8

OR8J3 OR8D1 OR8J1

1.02e-0349733155
GeneFamilyATP binding cassette subfamily C

CFTR ABCC10

1.22e-0313732807
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 PRUNE2 XPNPEP2 CUBN KCNH6 AGMO SLC6A20

1.84e-0718210074a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 PRUNE2 XPNPEP2 CUBN KCNH6 AGMO

2.89e-0617610061595dbeee336a81e581325d63208ec6262664ee9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 PRUNE2 XPNPEP2 CUBN AGMO SLC6A20

3.51e-061821006e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 PRUNE2 XPNPEP2 CUBN AGMO SLC6A20

3.51e-06182100657bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

XPNPEP2 ABCA9 ABCA8 SLCO1C1 VCAN AGMO

4.92e-061931006549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCellBronchus_Control_(B.)-Epithelial-TX-AT1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

MAS1 CFTR FSIP2 TENM3 HHAT SLC6A20

5.53e-061971006f7ef62d78336812573148f8bfce401877ec4e29c
ToppCell3'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC19A2 SLC43A3 LRP1B ABCA9 ABCA8 SLC7A10

5.69e-061981006abac765c4f6864bdb1700bc546c3b9771edc25c3
ToppCell3'-Adult-LymphNode-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC19A2 SLC43A3 LRP1B ABCA9 ABCA8 SLC7A10

5.69e-061981006ff57addcbdd53e5d2d0c80ec76b5eab3b3a67ca2
ToppCell3'-Adult-LymphNode-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC19A2 SLC43A3 LRP1B ABCA9 ABCA8 SLC7A10

5.69e-061981006698166b4ca173176ed563af6a1efc8c7d0a18e0b
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRUNE2 ABCA12 CUBN LRP1B EYS

1.56e-051391005a1945b07f177cde40e7eea03a19236ce76165857
ToppCellSevere-Myeloid-Mast-|Severe / Condition, Lineage, Cell class and cell subclass

PCDHGB5 ST8SIA1 PKDREJ LRP1B KCNH2

1.91e-051451005ce307d45425a5191882078f049f85477eec40b69
ToppCellSevere-Myeloid-Mast|Severe / Condition, Lineage, Cell class and cell subclass

PCDHGB5 ST8SIA1 PKDREJ LRP1B KCNH2

1.91e-051451005e0bfd2ffdbd6c197ef0a04e983396ebd87ef7127
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1|Striatum / BrainAtlas - Mouse McCarroll V32

DRD1 CFTR KCNH4 KCNH3 ABCC10

1.97e-0514610057b863f9bc63dc1afe015a18a70cd6ed0b71d1f09
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KCNH4 KCNH3 RGL1 SLC16A2 ACKR2

2.71e-0515610052cd007b423c2395c5ce331902e7f27c805755eb3
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_ALM_Oprk1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DRD1 MAS1 KCNH4 TENM3 ACKR2

3.25e-0516210052d28306c6125b31f11ea6d911a167b93a74907c5
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA9 ABCA8 SLCO1C1 TENM3 VCAN

3.35e-051631005bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA9 ABCA8 SLCO1C1 TENM3 VCAN

3.35e-0516310058e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA9 ABCA8 SLCO1C1 TENM3 TMBIM4

3.87e-051681005d19a115365c5415e51c039718d7669de788fcf33
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 PIGZ ABCA9 ANO8 NCKAP1L

3.87e-05168100504e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A18 ST8SIA1 B4GALT5 SLC16A2 SLC6A20

4.21e-05171100548fc4eca18b102b5ec5050f758281292ee8e10c6
ToppCelldroplet-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A18 ST8SIA1 B4GALT5 SLC16A2 SLC6A20

4.21e-05171100505fcc72df50a380a913821b5781d9621df37d328
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GPR82 ST8SIA1 NLRP9 SLC7A10 HACD1

4.32e-0517210059497948bbe53fb88c6ff6b347f743d456da587e5
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Mast_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OR2AK2 OR8D1 MFSD2B ST8SIA1 KCNH2

4.45e-051731005a7dee23b1d43d3070d502487af319ff81a9a747b
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM144 CFTR PIGZ NPC1L1 SLC6A20

4.70e-0517510056759d200a133034756de9cdf2d5daceca927aac9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 PRUNE2 CUBN KCNH6 GPR153

4.96e-0517710052f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 PRUNE2 XPNPEP2 CUBN AGMO

5.23e-051791005d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 CUBN RGL1 AGMO SLC6A20

6.27e-051861005a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC19A2 SLC43A3 LRP1B ABCA9 ABCA8

6.27e-0518610057582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 XPNPEP2 ABCA9 GPR153 VCAN

6.43e-0518710054e553721fa5598cb211f44e3226280b7e6885484
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 XPNPEP2 ABCA9 GPR153 VCAN

6.43e-051871005d36e7fc6125e7a4310499365022d38f34b757a73
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 XPNPEP2 ABCA9 GPR153 VCAN

6.43e-051871005827eae63fabf6892a82ce7779b5f395958d3d628
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BEST1 TMEM144 KCNH8 ABCA8 VCAN

6.59e-051881005d9692b6048d9b85524a07a1807bdd4757731c151
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BEST1 TMEM144 KCNH8 ABCA8 SLCO1C1

6.59e-051881005505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 CUBN TENM3 VCAN AGMO

6.76e-05189100528b502611829e4a24caff2562545c7db97686099
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BEST1 TMEM144 KCNH8 ABCA8 TAS2R39

6.93e-051901005396b7225c2430db3dc55a3d0db70239b71987229
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BEST1 TMEM144 KCNH8 ABCA8 SLCO1C1

7.11e-051911005f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BEST1 TMEM144 KCNH8 ABCA8 SLCO1C1

7.11e-051911005a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCellLA|World / Chamber and Cluster_Paper

PRUNE2 LRP1B ABCA9 ABCA8 VCAN

7.46e-051931005d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ST8SIA1 ABCA9 ABCA8 TENM3 VCAN

7.83e-051951005d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ST8SIA1 ABCA9 ABCA8 TENM3 VCAN

8.22e-0519710056d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PIGZ ABCA9 ABCA8 SLCO1C1 VCAN

8.22e-0519710056806ec223e542f0475303698eb78c1cc527f5c6b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ST8SIA1 ABCA9 ABCA8 TENM3 VCAN

8.22e-051971005b349f8e96d61a4c296af64711e11fc44459a9413
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ST8SIA1 ABCA9 ABCA8 TENM3 VCAN

8.22e-051971005c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM144 SLC26A3 XPNPEP2 CUBN SLC6A20

8.62e-051991005a10768e1cddd2d38291c30d24820a94040a72211
ToppCellSepsis-URO|Sepsis / Disease, condition lineage and cell class

BEST1 GRINA B4GALT5 RGL1 VCAN

8.62e-0519910058e6dac82d1d0e759cd567f9c95b70cb4801d7caf
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM144 SLC26A3 XPNPEP2 CUBN SLC6A20

8.62e-051991005f26c20f5d7470e90eaa79613d0b87bd4865585a8
ToppCellMacroglial|World / cells hierarchy compared to all cells using T-Statistic

BEST1 TMEM144 KCNH8 ABCA8 SLCO1C1

8.83e-052001005e6935ad49216d2500c15c05cbc2b89402c65e838
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRUNE2 ABCA9 RGL1 TENM3 VCAN

8.83e-052001005a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM144 SLC26A3 XPNPEP2 CUBN SLC6A20

8.83e-05200100573bfdf068a8ecbefc1e6afe9686df73658ee042f
Drugtrifluoroacetamide

MAS1 XPNPEP2 KL ACKR2

1.75e-0621974CID000067717
Diseaseshort QT syndrome (implicated_via_orthology)

KCNH6 KCNH2

2.75e-053902DOID:0050793 (implicated_via_orthology)
DiseaseIminoglycinuria

SLC6A18 SLC6A20

5.50e-054902C0268654
Diseaseepilepsy (implicated_via_orthology)

SCN11A LRP1B KCNH6 KCNH2 KCNT1

1.46e-04163905DOID:1826 (implicated_via_orthology)
Diseaselong QT syndrome (implicated_via_orthology)

KCNH6 KCNH2

4.07e-0410902DOID:2843 (implicated_via_orthology)
Diseaselifestyle measurement, alcohol consumption measurement

OR10J1 OR10J4 ACKR2 SLC7A10

4.32e-04115904EFO_0007878, EFO_0010724
Diseaselevel of Phosphatidylcholine (18:1_18:2) in blood serum

BEST1 HERPUD1

8.17e-0414902OBA_2045100
Diseaselevel of Sterol ester (27:1/18:0) in blood serum

NPC1L1 HERPUD1

1.07e-0316902OBA_2045196
Diseaseresponse to radiation, Urinary retention

LRP1B AGMO

1.21e-0317902GO_0009314, HP_0000016
DiseaseAntibody Deficiency Syndrome

EPG5 C8B

1.21e-0317902C0003257
DiseaseCCL4 measurement

SLC6A20 ACKR2

1.69e-0320902EFO_0004751
DiseaseCOVID-19, osteoarthritis

SLC6A20 ACKR2

1.69e-0320902MONDO_0005178, MONDO_0100096
Diseaselevel of Phosphatidylcholine (16:0_18:2) in blood serum

BEST1 HERPUD1

1.69e-0320902OBA_2045071
Diseaselevel of Phosphatidylcholine (16:1_18:2) in blood serum

BEST1 HERPUD1

1.86e-0321902OBA_2045083
Diseaseleptin measurement

NPBWR1 DRD1 LRP1B

1.97e-0381903EFO_0005000
DiseaseImmunologic Deficiency Syndromes

EPG5 C8B

2.23e-0323902C0021051
Diseasecoronary artery calcification

ST8SIA1 LRP1B FSIP2 EYS HERPUD1 OR5AP2

2.58e-03450906EFO_0004723

Protein segments in the cluster

PeptideGeneStartEntry
STLYTINFYSGIFFI

ACKR2

121

O00590
VDIVSYQSVLSYFSS

EPG5

2156

Q9HCE0
NSYAVIITSTSSYYV

CFTR

901

P13569
YYTDTTLAVSTFAKL

VCAN

2806

P13611
ASTFRLLTVFAYGTY

COPS7A

61

Q9UBW8
VTFVYTFTNIAYFTA

SLC7A10

276

Q9NS82
SLFFRSIELTSYIYI

AGMO

86

Q6ZNB7
IISFSTFIYYVSVNV

ABCA9

231

Q8IUA7
ILFLYFSDYSFSVIA

ABCA12

1146

Q86UK0
GYSVTTASFVTYVVR

ABCA12

1996

Q86UK0
LGRYYVTSAFTVAVS

AZIN2

276

Q96A70
YTQVVTVAVYSFFLT

BEST1

236

O76090
SRTYAISSSVISFYI

DRD1

191

P21728
YFIAFSSDQTSLEIY

DET1

71

Q7L5Y6
FFSLSSSLLYFVYVA

B4GALT5

21

O43286
AYAFFVTATYESLLR

ANO8

106

Q9HCE9
TSSLSLRYFTYGILF

SLC16A2

191

P36021
SSVSLFYGSIFFLYI

OR5K2

246

Q8NHB8
TYISIFLSTYRGFAS

RGL1

91

Q9NZL6
AATFSVFLSILYFYS

HERPUD1

271

Q15011
TLAVAVSYAFILYSI

OR8D1

211

Q8WZ84
AYITSLYFALSSLTS

KCNH3

451

Q9ULD8
SSDIRFYLTVYATIA

ABCC10

961

Q5T3U5
IYISNSIYFSIAIVS

CT55

126

Q8WUE5
IVVSLFYGTASLTYL

OR10A7

246

Q8NGE5
IVASLFYATTLFTYT

OR2AK2

261

Q8NG84
IVVSLFYSTAVSVYL

OR2B6

246

P58173
SLLTYSLDSTEYFTL

PCDHA3

166

Q9Y5H8
GFSFLVVLTSYYSFV

GPR82

211

Q96P67
ETNYIYFADTTSFLI

LRP1B

566

Q9NZR2
YVSYAVFFISLIVLS

GRINA

201

Q7Z429
VTSTVFLYFESVRTF

TMBIM4

51

Q9HC24
HYYTIVTLSVTFLFG

MAS1

101

P04201
YTSFLAYSRISDISF

EYS

2426

Q5T1H1
LTAAYTTLYALLFFS

GPR137

26

Q96N19
SLLTSFYFCIVTFST

KCNT1

281

Q5JUK3
YVTALYFTFSSLTSV

KCNH2

611

Q12809
DKYVTALYFTFSSLT

KCNH6

461

Q9H252
QLFYTSVYSSTFLED

FSIP2

4611

Q5CZC0
FSVLSALNELYFYVT

PLXNA3

1821

P51805
TYYFLSILALTDVSL

OR51H1

61

Q8NH63
FVSTFYTLTLATCFS

GPR153

86

Q6NV75
DFTRSYLDLIVTYTS

NCKAP1L

126

P55160
IYYVFFTTSVLTCSA

NIPA2

251

Q8N8Q9
YIAALYFTLSSLTSV

KCNH4

426

Q9UQ05
ETIFYSSYVFFTKLS

MFSD2B

411

A6NFX1
LFKLATTALYFTYSA

HMOX2

66

P30519
TVVSLSYGTIFAVYL

OR1I1

246

O60431
EITYSFYRTGQIFSL

PCDHGB5

276

Q9Y5G0
TAVTIFYGTLIFSYI

OR5J2

246

Q8NH18
YFFLSSLSFVDASYS

OR5AP2

66

Q8NGF4
SLTYLYGFSTAIVVS

OR8J3

146

Q8NGG0
LTAVSLFYTSGIFVY

OR5AN1

246

Q8NGI8
LFYTSGIFVYLSSSS

OR5AN1

251

Q8NGI8
VLLVSFFFITISYAY

OR10Z1

206

Q8NGY1
LLVVSLFYSTAILTY

OR10A4

246

Q9H209
CSSSYVLFLSIVYAL

GPR149

186

Q86SP6
IAGFLIAVSYTTSFY

OR5P2

146

Q8WZ92
FTLTVRCLYYTSFSL

HHAT

171

Q5VTY9
FATSYIVIFLYISLA

NPC1L1

636

Q9UHC9
SLTYLYGFSTAIVVS

OR8J1

146

Q8NGP2
YGFSTAIVVSSYVFS

OR8J1

151

Q8NGP2
FSYYKIVFSILRISS

OR7C1

216

O76099
SVYNFLYVTFVKSSS

CUBN

901

O60494
TVTEITRYSFYTFSL

HACD1

176

B0YJ81
YVESILLYTLTTAFT

SELENOI

341

Q9C0D9
FASIISLSLIFYYSK

KL

991

Q9UEF7
YTFSRAAILLSIVYF

HERPUD2

281

Q9BSE4
AAILLSIVYFYSSFS

HERPUD2

286

Q9BSE4
EITTQFLIYASYFAL

SLC19A2

451

O60779
DSSVFGAIYYVVFTT

NIPA1

256

Q7RTP0
YELVTATDFAYSSTV

C8B

471

P07358
LGNLSEFLTTSFYTY

PHKA2

601

P46019
EFLTTSFYTYLTFLD

PHKA2

606

P46019
IAISYFITSLSYANS

NPBWR1

286

P48145
YFFLSMLSTSETVYT

OR10J1

71

P30954
LLVVSLFYISSSLTY

OR10A5

246

Q9H207
YFFLSVLSISETYYT

OR10J4

61

P0C629
ISSTSLSFYSEDAVY

TAS2R39

96

P59534
YSSSAQFYVTFAVFV

SYPL1

111

Q16563
IVTTATLAYFIFYHI

RNF133

196

Q8WVZ7
DLDSLISTFTYAYFL

PRUNE2

31

Q8WUY3
ATSSISSFFIVFYGL

PKDREJ

1586

Q9NTG1
AFVIFSLFTLASIYT

SMIM31

16

A0A1B0GVY4
FLYSFTIDNSTYSLF

ST8SIA1

111

Q92185
FFYTTATLIIAFTSA

SLC43A3

106

Q8NBI5
TISFVSCIIQSYLYF

OR6T1

91

Q8NGN1
FAVAFSVASVYSLKY

SLC26A3

351

P40879
TAVTLFYGTITFIYV

OR5P3

246

Q8WZ94
TSIFASIVTFSIYGF

SLC6A20

286

Q9NP91
TLSFLISLYYNTIVA

SLC6A18

106

Q96N87
ISFSSFIYYASVNVT

ABCA8

231

O94911
YLYASFLTTVFKAGS

NLRP9

366

Q7RTR0
FVYGTTYQFVLTTEI

TXNDC16

181

Q9P2K2
FSGIFLTSTVYFLAY

TMEM144

236

Q7Z5S9
VISCYVTYLTFSALS

SERINC5

266

Q86VE9
FLYFLVISVITSYTL

SLCO1C1

551

Q9NYB5
LSEILYDSTRVSFTY

TENM3

1956

Q9P273
LLSGSYVTLVFYTRT

PIGZ

161

Q86VD9
YVTLVFYTRTFSNTI

PIGZ

166

Q86VD9
IYCLVTLVFFYSSAS

TMEM208

36

Q9BTX3
TSYFVSYIIISFLIV

SCN11A

1581

Q9UI33
FFYSYTLLTDSSIRL

XPNPEP2

261

O43895
TISFFSSLKFIRYIY

TM9SF1

586

O15321
VSTFALCYALSFITY

VN1R2

321

Q8NFZ6
SFITYVYLALFDNSS

VN1R2

331

Q8NFZ6
SIRSAYIAALYFTLS

KCNH8

416

Q96L42
YIAALYFTLSSLTSV

KCNH8

421

Q96L42