Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmethylated histone binding

TTLL12 ZMYND11 MORC3

2.88e-0486303GO:0035064
GeneOntologyMolecularFunctionmethylation-dependent protein binding

TTLL12 ZMYND11 MORC3

3.08e-0488303GO:0140034
DomainPHD

ZMYND11 KAT6A

6.02e-0375292PF00628
DomainZnf_PHD-finger

ZMYND11 KAT6A

6.66e-0379292IPR019787
DomainTyrKc

KDR INSRR

8.20e-0388292SM00219
DomainTyr_kinase_cat_dom

KDR INSRR

8.20e-0388292IPR020635
DomainPHD

ZMYND11 KAT6A

8.38e-0389292SM00249
DomainZnf_PHD

ZMYND11 KAT6A

8.75e-0391292IPR001965
DomainKinase-like_dom

KDR TRRAP NUAK2 INSRR

9.37e-03542294IPR011009
DomainZF_PHD_2

ZMYND11 KAT6A

9.51e-0395292PS50016
DomainZF_PHD_1

ZMYND11 KAT6A

9.70e-0396292PS01359
DomainPROTEIN_KINASE_TYR

KDR INSRR

9.89e-0397292PS00109
DomainTyr_kinase_AS

KDR INSRR

9.89e-0397292IPR008266
Pubmed

Myoferlin silencing inhibits VEGFR2-mediated proliferation of metastatic clear cell renal cell carcinoma.

MYOF KDR

7.19e-07230231477752
Pubmed

Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function.

MYOF KDR

4.31e-06430217702744
Pubmed

Studies on human DNA polymerase epsilon and GINS complex and their role in DNA replication.

GINS2 POLA1

3.22e-051030221705323
Pubmed

CUL2LRR1 , TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle.

GINS2 POLA1

7.50e-051530233590678
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

CKAP5 MYOF RXFP1 TRRAP

8.54e-0527230431010829
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ZMYND11 MORC3 TRRAP POLA1 KAT6A

1.59e-0460830536089195
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

CKAP5 MYOF TNS3 KAT6A

1.84e-0433230437433992
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

CKAP5 TTLL12 MORC3 POLA1

1.84e-0433230432786267
Pubmed

HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development.

KDR KAT6A

1.96e-042430221149574
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MFN2 MYOF TRRAP IQGAP3 KAT6A MYOM3

3.13e-04110530635748872
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CKAP5 TTLL12 RXFP1 POLA1 MYOM3

3.85e-0473630529676528
Pubmed

Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1.

TTLL12 MORC3

5.78e-04413028590280
Pubmed

Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.

ZMYND11 TRRAP

6.06e-044230235705031
Pubmed

ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

TRRAP KAT6A

6.06e-044230216387653
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

CKAP5 MYOF IQGAP3

6.98e-0420230333005030
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CKAP5 TTLL12 MORC3 TNS3 NUAK2

7.83e-0486130536931259
CytobandEnsembl 112 genes in cytogenetic band chr8p11

GOT1L1 KAT6A

2.08e-03103302chr8p11
GeneFamilyReceptor Tyrosine Kinases|CD molecules

KDR INSRR

8.84e-0440202321
GeneFamilyPHD finger proteins

ZMYND11 KAT6A

4.39e-039020288
GeneFamilyFibronectin type III domain containing

INSRR MYOM3

1.33e-02160202555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

KDR MYOM3

1.35e-02161202593
GeneFamilyImmunoglobulin like domain containing

KDR MYOM3

1.90e-02193202594
CoexpressionGSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_DN

CKAP5 GINS2 MYOF SLC43A3 CCL22 POLA1 RAD54L

2.38e-09200307M5292
CoexpressionGSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_DN

CKAP5 GINS2 MYOF SLC43A3 POLA1 RAD54L

9.33e-08200306M5294
CoexpressionGSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_DN

CKAP5 MYOF SLC43A3 CCL22 TNS3

3.00e-06200305M5296
CoexpressionGSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_DN

CKAP5 GINS2 SLC43A3 POLA1 TNS3

3.00e-06200305M5300
CoexpressionGSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_DN

CKAP5 MFN2 TRRAP KAT6A

7.57e-05199304M5249
CoexpressionGSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4_KO_BCELL_UP

TTLL12 MFN2 MYOF SLC43A3

7.72e-05200304M9807
CoexpressionGSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_DN

MFN2 MYOF SLC43A3 CCL22

7.72e-05200304M5288
CoexpressionGSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN

GINS2 SLC43A3 RAD54L TNS3

7.72e-05200304M3188
CoexpressionGSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_UP

GINS2 POLA1 IQGAP3 RAD54L

7.72e-05200304M3577
CoexpressionGSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_DN

CKAP5 GINS2 MYOF SLC43A3

7.72e-05200304M5303
CoexpressionGOLDRATH_EFF_VS_MEMORY_CD8_TCELL_UP

CKAP5 DNAJC1 POLA1 IQGAP3

7.72e-05200304M3041
CoexpressionMORI_IMMATURE_B_LYMPHOCYTE_DN

CKAP5 IQGAP3 RAD54L

1.54e-0491303M18917
CoexpressionMORI_IMMATURE_B_LYMPHOCYTE_DN

CKAP5 IQGAP3 RAD54L

1.64e-0493303MM1138
CoexpressionHE_LIM_SUN_FETAL_LUNG_C5_PRO_B_CELL

CKAP5 GINS2 SLC43A3 POLA1 RAD54L

1.93e-04478305M45785
CoexpressionHOEK_NK_CELL_2011_2012_TIV_7D_VS_0DY_ADULT_7D_DN

GINS2 RAD54L

2.14e-0419302M41078
CoexpressionFOURNIER_ACINAR_DEVELOPMENT_LATE_2

CKAP5 TTLL12 GINS2 POLA1

2.84e-04281304M4077
CoexpressionAtlasMyeloid Cells, DC.4+.SLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3

MYOF KDR CCL22 PIK3R6 TNS3 NUAK2

1.56e-05407296GSM538245_500
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRIN3B POLA1 IQGAP3 RAD54L

4.88e-061693040bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCellCV-Healthy-4|Healthy / Virus stimulation, Condition and Cluster

GINS2 SLC43A3 PIK3R6 INSRR

5.47e-0617430426544cc5f51cb4dc1251e62d9f80b6c956194d38
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GINS2 POLA1 IQGAP3 RAD54L

5.60e-06175304a6913f992a1ea20b43e5adeca3ede3a6fda820ad
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GINS2 POLA1 IQGAP3 RAD54L

6.12e-0617930488d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GINS2 POLA1 IQGAP3 RAD54L

6.12e-0617930480112c686a8f85ad5e3cda6e3f3d3d51cf688092
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GINS2 POLA1 IQGAP3 RAD54L

6.26e-06180304f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCellIIH-cycling-|IIH / Condition, Cell_class and T cell subcluster

GINS2 RXFP1 IQGAP3 RAD54L

6.40e-061813047f4fed9e296bc22cb5a1e6c8e3c4b641e97c3078
ToppCellIIH-cycling|IIH / Condition, Cell_class and T cell subcluster

GINS2 RXFP1 IQGAP3 RAD54L

6.40e-06181304ec3e782ce93dcfe1a54fb7284e4e39063614b0e2
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CKAP5 GINS2 IQGAP3 RAD54L

6.68e-06183304e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCellMatrixFB-Fibroblast-E_(Early_Fibroblastic_progenitor)|MatrixFB / shred on cell class and cell subclass (v4)

SLC43A3 POLA1 IQGAP3 RAD54L

7.43e-06188304b240ea20750ffb825cb5fe41d06c632233406ab6
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CKAP5 POLA1 IQGAP3 RAD54L

7.75e-06190304d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKAP5 NYAP1 POLA1 RAD54L

7.75e-06190304b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GINS2 POLA1 IQGAP3 RAD54L

7.91e-0619130415dbc5a03bfab8931c0fd385b0f25874736ae874
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GINS2 POLA1 IQGAP3 RAD54L

7.91e-0619130445c15f5ce4a207ac944bed65d45f06c1657d1a6d
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDR SLC43A3 NYAP1 TNS3

8.08e-061923046806a1a9fe00395dc1abc3e0124b4261dc701f31
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-Cycling_T|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

GINS2 IQGAP3 RAD54L INSRR

8.24e-0619330481e6240cffb094b2aa3684fd0889b6497f47c4f0
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CKAP5 POLA1 IQGAP3 RAD54L

8.24e-061933044b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GINS2 KDR SLC43A3 POLA1

8.41e-06194304ae6d5cf4c825b29e677296df2c0985431c83b82e
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|367C / Donor, Lineage, Cell class and subclass (all cells)

CKAP5 GINS2 IQGAP3 RAD54L

8.41e-06194304a12b64945e10f00aa983678a02586c59badc1570
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CKAP5 GINS2 IQGAP3 RAD54L

8.76e-061963049591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GINS2 SLC43A3 POLA1 RAD54L

8.94e-06197304d9978aaa476b57144b0561f535ff1dd886c7512b
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CKAP5 KDR SLC43A3 IQGAP3

8.94e-06197304a41420d4b6d502c2f594c054c7efbb5d4eac83ff
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1|bone_marrow / Manually curated celltypes from each tissue

GINS2 SLC43A3 IQGAP3 RAD54L

9.12e-061983045c92687b853ebb00960adbef6552f9d460bc6886
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

CKAP5 GINS2 IQGAP3 RAD54L

9.12e-06198304880f9817f5145f10f29fc05c5866090433532fe2
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GINS2 SLC43A3 POLA1 RAD54L

9.12e-06198304c78ff8fc71dfcba1ac0c373bc90ea7b87c5699a4
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GINS2 SLC43A3 POLA1

1.27e-041463032d907e50206c4762a8baa741363bc7f0a04bd84e
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIK3R6 POLA1 IQGAP3

1.58e-04157303904cd98ae85ed6459e0663f077ac462842bf12df
ToppCellAdult-Immune-mast_cell-D231|Adult / Lineage, Cell type, age group and donor

PIK3R6 IQGAP3 RAD54L

1.58e-041573034c63bb91f8708644e6ce2500072a4eeb8e1079dd
ToppCell390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

GINS2 NYAP1 RAD54L

1.64e-041593030fbfdb18b7ed4bde077add13f2b3636e144b254f
ToppCellAdult-Immune-mast_cell|Adult / Lineage, Cell type, age group and donor

PIK3R6 IQGAP3 RAD54L

1.70e-0416130344f5c0256b3ce264a6c7b62740f32dcd45ee052d
ToppCell390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GINS2 NYAP1 RAD54L

1.76e-04163303aa5ea367f787c1543afb7eb80a801432e1c44011
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CKAP5 IQGAP3 RAD54L

1.76e-041633035285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GINS2 POLA1 IQGAP3

1.86e-04166303575c325db88d6909cdf0d5e664bd9098b89d4401
ToppCelldroplet-Thymus-nan-3m-Myeloid-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCL22 PIK3R6 NUAK2

1.86e-04166303c0af93db981dfd448abc7efcd257f3e5ff066aae
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GINS2 IQGAP3 RAD54L

1.86e-0416630321ba5fd755c0fb31ada42a1b5d60bede0153323d
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

GINS2 IQGAP3 RAD54L

1.89e-041673033461d14e36f09ddc6ee5549ca4797e16d3f37fcc
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL12 MYOF FAM220A

1.93e-041683032e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCelldroplet-Lung-nan-18m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GINS2 POLA1 RAD54L

1.93e-0416830396f7411474edd673b8d3ee6b8a8bb185c246daaf
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GINS2 POLA1 RAD54L

1.96e-04169303121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

GINS2 IQGAP3 RAD54L

1.96e-04169303a949f547b53126a208819bade74a1ac9b2a36ea7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GINS2 POLA1 RAD54L

1.96e-04169303e7514956b2e4298222ec443f98b2f5289451786e
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

GINS2 IQGAP3 RAD54L

1.96e-04169303195d5cd60d646ac6d40a3321b2f739917e7aef14
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CKAP5 IQGAP3 RAD54L

1.96e-04169303e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GINS2 POLA1 RAD54L

2.00e-04170303badbe200e9d5003d23d115955b10b4ea767f6c26
ToppCell10x5'-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T|Lung / Manually curated celltypes from each tissue

GINS2 RAD54L INSRR

2.03e-04171303976361f67dd725870e0513ae7a92f2dcaee17148
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GINS2 POLA1 RAD54L

2.07e-041723037c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GINS2 CCL22 POLA1

2.10e-0417330315af4a0f7516dbf5c93ba66a19aca073ebe30d04
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GINS2 POLA1 RAD54L

2.10e-0417330320a20429aa898097d5ec4880ed64846558b5890f
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_2|343B / Donor, Lineage, Cell class and subclass (all cells)

GINS2 IQGAP3 RAD54L

2.14e-04174303a75ba49ccea6bd3d78ada1092b46deb5202c58a5
ToppCelldroplet-Lung-21m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GINS2 IQGAP3 RAD54L

2.17e-041753036751ee4b312d7f87275f2c35e5878cfc3be3ebe3
ToppCell390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

GINS2 NYAP1 RAD54L

2.21e-04176303941e8724b6f680719ef2a4f190f943b205bb9e78
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GINS2 POLA1 TNS3

2.21e-04176303cb8fd56a4f935cdda19d7ab43382cdda7c307667
ToppCellfacs-Pancreas-Endocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDR SLC43A3 PIK3R6

2.21e-0417630392ebcea9b2b22601234b76d7a98f0410b905a87b
ToppCellfacs-Pancreas-Endocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDR SLC43A3 PIK3R6

2.21e-041763039ddf87e586d2378984cd007c60f7dc254845f8f3
ToppCellfacs-Pancreas-Endocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDR SLC43A3 PIK3R6

2.21e-04176303e987e741fcf1bed8598a5060700efd3018f8123b
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CKAP5 KDR SLC43A3

2.21e-041763038385435074cc5235b7af7424974f609388fc2cff
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 SLC43A3 DNAI7

2.25e-04177303ae01c19403a09f7ba5e4beafdfcd1b8eebdadcb7
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KDR RXFP1 NUAK2

2.25e-0417730316197068260fc062bf8b730a51a199887ea580b9
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 SLC43A3 DNAI7

2.25e-04177303bd3d07bdef6e903995d4bbfb6ff3a5e1d9fb70cc
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_1|367C / Donor, Lineage, Cell class and subclass (all cells)

GINS2 IQGAP3 RAD54L

2.25e-04177303ba701d3c90722d8bff70d0fa651899305cdad257
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CKAP5 POLA1 IQGAP3

2.32e-0417930354191c00b29f53b520cd3243b5791daa4a2c72d7
ToppCell10x5'-blood-Lymphocytic_NK-Cycling_NK|blood / Manually curated celltypes from each tissue

GINS2 POLA1 RAD54L

2.32e-04179303c93711273055a999335ba8d0f6500e4549f46cec
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CKAP5 GINS2 IQGAP3

2.32e-04179303ac987c9425a1b4106d1b8779a2c5461383eae2ae
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GINS2 SLC43A3 IQGAP3

2.32e-04179303e1bfd553c043ebc070ccf8545d489ba16d9b2ef4
ToppCelldroplet-Fat-Gat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDR PIK3R6 RAD54L

2.32e-0417930308cf9986804a6417a9afb19b50c69a3554f71ec6
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CKAP5 IQGAP3 RAD54L

2.36e-04180303334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDR SLC43A3 TNS3

2.40e-04181303a53f05c4c47465ee62e353716456bd09ab464b23
ToppCellP15-Endothelial-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GINS2 IQGAP3 RAD54L

2.40e-041813030c5bc1660b8fc1e905ab4230202862de5be46ebd
ToppCellP28-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GINS2 IQGAP3 RAD54L

2.40e-04181303e482fd116c00ff4d8db7be3c06b1bd1ffa2d479d
ToppCellP15-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GINS2 IQGAP3 RAD54L

2.40e-04181303f83565f09dd971c5cad2704a4a86bca0accd955e
ToppCellP28-Endothelial-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GINS2 IQGAP3 RAD54L

2.40e-041813032be3d44619adb25d339e7a27b500a56e07e8de01
ToppCellsevere-multiplets|World / disease stage, cell group and cell class

GINS2 IQGAP3 RAD54L

2.44e-041823035e30ec7120a988d9ee3000513e1209618f28f5f9
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

KDR SLC43A3 PIK3R6

2.44e-04182303fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCelldroplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDR SLC43A3 TNS3

2.44e-04182303b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GINS2 POLA1 RAD54L

2.44e-0418230311494a66d986297b837332ee9d382b71b9f22591
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CKAP5 GINS2 POLA1

2.48e-04183303ba7753e9fe2a6a87c5264f299ac97da2ddbda178
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDR SLC43A3 TNS3

2.48e-04183303709a486154b3157427deb3b8886b63ac39ea42dd
ToppCelldroplet-Liver-nan-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDR SLC43A3 TNS3

2.48e-04183303dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GINS2 IQGAP3 RAD54L

2.48e-0418330342dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GINS2 POLA1 RAD54L

2.48e-041833036c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GINS2 IQGAP3 RAD54L

2.52e-041843036b2449ac65a2322aa0479fba0d89828f243aabbe
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GINS2 IQGAP3 RAD54L

2.52e-04184303e90622b82fa7f16a1faaf7a4724c958f2d83341d
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKAP5 POLA1 IQGAP3

2.52e-0418430316aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CKAP5 POLA1 IQGAP3

2.56e-04185303b4af9ae4c358b48357cb135b740266e1652d886a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CKAP5 IQGAP3 RAD54L

2.56e-0418530330e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GINS2 IQGAP3 RAD54L

2.56e-0418530357c1eb50a4456d20953e48d5dc3b0ea3d0d81b6d
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAI7 GRIN3B ZNF474

2.56e-041853035e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_bronchial_(8)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KDR RXFP1 PIK3R6

2.60e-041863030cc7504297fd0c97ea50e4b3ff58fcedc4c1cfaa
ToppCell356C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|356C / Donor, Lineage, Cell class and subclass (all cells)

GINS2 IQGAP3 RAD54L

2.60e-04186303189b75aa98903f1cb65b624524ba6c30df7e42ff
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAI7 GRIN3B ZNF474

2.60e-0418630376033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell356C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|356C / Donor, Lineage, Cell class and subclass (all cells)

GINS2 IQGAP3 RAD54L

2.60e-04186303261891d0b148e285339ae0b9e36136ceabd9b6f5
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KDR RXFP1 PIK3R6

2.64e-0418730329b2e2be26a9d72b154760e47acf61cfe2f45fa7
ToppCelldroplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GINS2 POLA1 RAD54L

2.68e-041883030ec2a1b0505501ba18f10a5fce68c306a6292419
ToppCelltumor_Lung-Epithelial_cells-tS3|tumor_Lung / Location, Cell class and cell subclass

DNAI7 GRIN3B ZNF474

2.68e-0418830326326b4e298e33f9ba393fc632238aa8c54b1ea3
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GINS2 POLA1 RAD54L

2.68e-0418830361ae7405ab56570409bf35382dc0a038e4137c15
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KDR RXFP1 PIK3R6

2.68e-04188303b9c5d573fc5ab0f7f38c55d006f9576634b05462
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-T_NK_proliferative|Multiple_Sclerosis / Disease, Lineage and Cell Type

GINS2 IQGAP3 RAD54L

2.68e-041883036c05797a5d0635d89ffcf4aca52178687129ccb4
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GINS2 IQGAP3 RAD54L

2.72e-04189303fd8834d1feb7f63911c5fa51efb1f679a8baddeb
ToppCelldroplet-Pancreas-Endocrine-21m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDR SLC43A3 PIK3R6

2.72e-0418930337ce47abd6f96df04d35a4a6189d007bef5ccc94
ToppCell368C-Lymphocytic-NK_cells-Proliferating_NK_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

GINS2 POLA1 RAD54L

2.72e-0418930331d34bc75d4457fca197e1766922e987dbd5f8a9
DiseaseAdenoid Cystic Carcinoma

GINS2 KAT6A INSRR

1.29e-04100293C0010606
DiseaseNodular glomerulosclerosis

MFN2 KDR

7.47e-0441292C0017667
DiseaseDiabetic Nephropathy

MFN2 KDR

8.60e-0444292C0011881
Diseasepulmonary fibrosis (biomarker_via_orthology)

MFN2 CCL22

1.11e-0350292DOID:3770 (biomarker_via_orthology)
Diseasechronic obstructive pulmonary disease (is_marker_for)

KDR CCL22

4.10e-0397292DOID:3083 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
KEWLEPKPLCFMEVL

FAM228B

21

P0C875
CADPRVPWVKMILNK

CCL22

76

O00626
PLERPCFRMKLSGWE

C2orf48

106

Q96LS8
PKDMDPRLIAWKGGA

ACTR8

576

Q9H981
WDPKKLCMDPDILLN

GOT1L1

156

Q8NHS2
LSCSLKKRMPEGPWP

FAM220A

26

Q7Z4H9
ERLLMKPQWHDLLPC

DNAJC1

211

Q96KC8
LMWTLLRQSPECKPE

RAD54L

196

Q92698
CLKWRKLPDGMDQLP

MORC3

416

Q14149
LFLMNRKIKGPCWLE

POLA1

486

P09884
KRWMEACLKEELPSP

IQGAP3

41

Q86VI3
VMWPNSKCPLLKDDL

MFN2

181

O95140
PKGMWICQICRPRKK

KAT6A

301

Q92794
PCQALVRMLAKKPGW

CKAP5

636

Q14008
LELPPQCKPVKGWMI

DNAI7

391

Q6TDU7
KGLLPVRWMAPESLK

INSRR

1151

P14616
RGLCKQESMPILPSW

NYAP1

801

Q6ZVC0
TPKCPTGRLLMNLWA

GRIN3B

636

O60391
GIKKRAWPLDFLMPG

PIK3R6

371

Q5UE93
QKCRLLPPEWMDVEK

GINS2

56

Q9Y248
CAPWNGLLMDRLKQK

SLC43A3

331

Q8NBI5
PKPSDACGLIRWLLM

NUAK2

271

Q9H093
CALDPQDRKWIKDGP

TNS3

1381

Q68CZ2
MSLQWNLIRKLPPDC

RXFP1

131

Q9HBX9
ETDPLIRKCMLLPWA

TTLL12

246

Q14166
PCIPNHELVWAKMKG

ZMYND11

276

Q15326
PKCLEKWKMENDRLP

ZNF474

241

Q6S9Z5
RKGDARLPLKWMAPE

KDR

1061

P35968
CVNLLKTALRPDMWP

TRRAP

2126

Q9Y4A5
PKLLWHPVMNGDKAC

MYOF

1246

Q9NZM1
CGKNEMVIGWKPPKR

MYOM3

711

Q5VTT5