Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	peptidyltransferase activity	GGT2P GGT1 GGT3P	2.41e-06	6	100	3	GO:0000048
GeneOntologyMolecularFunction	leukotriene-C(4) hydrolase	GGT2P GGT1 GGT3P	2.41e-06	6	100	3	GO:0002951
GeneOntologyMolecularFunction	leukotriene C4 gamma-glutamyl transferase activity	GGT2P GGT1 GGT3P	6.70e-06	8	100	3	GO:0103068
GeneOntologyMolecularFunction	glutathione hydrolase activity	GGT2P GGT1 GGT3P	1.00e-05	9	100	3	GO:0036374
GeneOntologyMolecularFunction	catalytic activity, acting on RNA	PUS3 DDX31 DDX27 GGT2P GGT1 GGT3P DDX6 SEPSECS VARS1 DDX28	4.60e-05	417	100	10	GO:0140098
GeneOntologyMolecularFunction	omega peptidase activity	GGT2P GGT1 GGT3P	6.51e-05	16	100	3	GO:0008242
GeneOntologyMolecularFunction	aminoacyltransferase activity	HECW1 TRIM54 RNF213 GGT2P GGT1 GGT3P RNF113B FBXW8 TRIM56 TRIM55 HERC1	7.22e-05	532	100	11	GO:0016755
GeneOntologyMolecularFunction	catalytic activity, acting on a tRNA	PUS3 GGT2P GGT1 GGT3P SEPSECS VARS1	8.66e-05	144	100	6	GO:0140101
GeneOntologyMolecularFunction	threonine-type peptidase activity	GGT2P GGT1 GGT3P	1.31e-04	20	100	3	GO:0070003
GeneOntologyMolecularFunction	acyltransferase activity	HECW1 TRIM54 RNF213 GGT2P GGT1 GGT3P RNF113B FBXW8 CPT1C TRIM56 TRIM55 HERC1	4.93e-04	775	100	12	GO:0016746
GeneOntologyMolecularFunction	RNA helicase activity	DDX31 DDX27 DDX6 DDX28	6.36e-04	78	100	4	GO:0003724
GeneOntologyMolecularFunction	histone H3K4 demethylase activity	KDM5B KDM1A	6.82e-04	8	100	2	GO:0032453
GeneOntologyMolecularFunction	ATP-dependent activity, acting on RNA	DDX31 DDX27 DDX6 DDX28	7.00e-04	80	100	4	GO:0008186
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	PUS3 DDX31 DDX27 GGT2P GGT1 GGT3P DDX6 SEPSECS VARS1 DDX28	1.47e-03	645	100	10	GO:0140640
GeneOntologyMolecularFunction	ATP hydrolysis activity	DDX31 ABCB5 RNF213 DDX27 DDX6 KIF7 KIF14 DDX28	1.68e-03	441	100	8	GO:0016887
GeneOntologyBiologicalProcess	cysteine biosynthetic process	GGT2P GGT1 GGT3P	6.08e-06	8	100	3	GO:0019344
GeneOntologyBiologicalProcess	peptide modification	GGT2P GGT1 GGT3P	1.29e-05	10	100	3	GO:0031179
GeneOntologyBiologicalProcess	leukotriene D4 biosynthetic process	GGT2P GGT1 GGT3P	1.29e-05	10	100	3	GO:1901750
GeneOntologyBiologicalProcess	glutathione catabolic process	GGT2P GGT1 GGT3P	1.77e-05	11	100	3	GO:0006751
GeneOntologyBiologicalProcess	leukotriene D4 metabolic process	GGT2P GGT1 GGT3P	2.36e-05	12	100	3	GO:1901748
GeneOntologyBiologicalProcess	modified amino acid catabolic process	GGT2P GGT1 GGT3P ALDH1L2	3.04e-05	37	100	4	GO:0042219
GeneOntologyBiologicalProcess	serine family amino acid metabolic process	GGT2P GGT1 GGT3P GLDC	5.55e-05	43	100	4	GO:0009069
GeneOntologyBiologicalProcess	cysteine metabolic process	GGT2P GGT1 GGT3P	5.91e-05	16	100	3	GO:0006534
GeneOntologyBiologicalProcess	fatty acid derivative biosynthetic process	GGT2P GGT1 GGT3P ACSF3	1.18e-04	52	100	4	GO:1901570
GeneOntologyBiologicalProcess	glutathione biosynthetic process	GGT2P GGT1 GGT3P	1.19e-04	20	100	3	GO:0006750
GeneOntologyBiologicalProcess	sulfur amino acid biosynthetic process	GGT2P GGT1 GGT3P	1.38e-04	21	100	3	GO:0000097
GeneOntologyBiologicalProcess	nonribosomal peptide biosynthetic process	GGT2P GGT1 GGT3P	1.59e-04	22	100	3	GO:0019184
GeneOntologyBiologicalProcess	leukotriene biosynthetic process	GGT2P GGT1 GGT3P	1.59e-04	22	100	3	GO:0019370
GeneOntologyBiologicalProcess	serine family amino acid biosynthetic process	GGT2P GGT1 GGT3P	2.35e-04	25	100	3	GO:0009070
GeneOntologyBiologicalProcess	proteinogenic amino acid biosynthetic process	ASNSD1 GGT2P GGT1 GGT3P	3.53e-04	69	100	4	GO:0170038
GeneOntologyBiologicalProcess	L-amino acid biosynthetic process	ASNSD1 GGT2P GGT1 GGT3P	3.73e-04	70	100	4	GO:0170034
HumanPheno	Abnormal corpus callosum morphology	HSPG2 KDM5B PUS3 WT1 GGT1 DDX6 WAC KIF7 TBC1D20 SYNGAP1 B9D2 SEPSECS GLDC KIF14 COASY HERC1 VARS1 KDM1A	3.16e-06	937	33	18	HP:0001273
HumanPheno	Aplasia/Hypoplasia of the corpus callosum	HSPG2 KDM5B PUS3 WT1 GGT1 DDX6 WAC KIF7 TBC1D20 B9D2 SEPSECS GLDC KIF14 COASY VARS1 KDM1A	6.14e-06	772	33	16	HP:0007370
HumanPheno	Hypoplasia of the corpus callosum	KDM5B PUS3 WT1 DDX6 WAC KIF7 TBC1D20 SEPSECS KIF14 COASY VARS1 KDM1A	2.29e-05	478	33	12	HP:0002079
HumanPheno	Thin corpus callosum	HSPG2 KDM5B PUS3 WT1 GGT1 DDX6 WAC KIF7 TBC1D20 B9D2 SEPSECS GLDC KIF14 COASY VARS1 KDM1A	2.87e-05	868	33	16	HP:0033725
HumanPheno	Abnormal cerebral white matter morphology	HSPG2 KDM5B PUS3 WT1 GGT1 DDX6 WAC KIF7 TBC1D20 SYNGAP1 B9D2 SEPSECS GLDC KIF14 COASY HERC1 VARS1 KDM1A	4.00e-05	1114	33	18	HP:0002500
HumanPheno	Abnormal cerebral subcortex morphology	HSPG2 KDM5B PUS3 WT1 GGT1 DDX6 WAC KIF7 TBC1D20 SYNGAP1 B9D2 SEPSECS GLDC KIF14 COASY HERC1 VARS1 KDM1A	1.24e-04	1207	33	18	HP:0010993
MousePheno	decreased cysteine level	GGT2P GGT1 GGT3P ALDH1L2	6.17e-08	8	78	4	MP:0030623
MousePheno	ovary hypoplasia	GGT2P GGT1 GGT3P CBFA2T2	1.84e-07	10	78	4	MP:0005158
MousePheno	abnormal cysteine level	GGT2P GGT1 GGT3P ALDH1L2	6.17e-07	13	78	4	MP:0030621
MousePheno	decreased glutathione level	GGT2P GGT1 GGT3P ALDH1L2	6.17e-07	13	78	4	MP:0012604
MousePheno	abnormal glutathione level	GGT2P GGT1 GGT3P ALDH1L2	6.17e-07	13	78	4	MP:0012603
MousePheno	abnormal circulating glutathione level	GGT2P GGT1 GGT3P	1.66e-06	5	78	3	MP:0030652
MousePheno	increased circulating glutathione level	GGT2P GGT1 GGT3P	1.66e-06	5	78	3	MP:0030653
MousePheno	glutathionuria	GGT2P GGT1 GGT3P	1.66e-06	5	78	3	MP:0013730
MousePheno	increased glutathione level	GGT2P GGT1 GGT3P	1.66e-06	5	78	3	MP:0012606
MousePheno	decreased circulating cysteine level	GGT2P GGT1 GGT3P	5.76e-06	7	78	3	MP:0030626
MousePheno	epididymis hypoplasia	GGT2P GGT1 GGT3P	9.17e-06	8	78	3	MP:0004932
MousePheno	nuclear cataract	GGT2P GGT1 GGT3P TBC1D20	1.22e-05	26	78	4	MP:0010254
MousePheno	nervous	GGT2P GGT1 GGT3P	1.37e-05	9	78	3	MP:0008912
MousePheno	abnormal reproductive system development	WT1 RIPK4 GGT2P GGT1 GGT3P KIF7	1.84e-05	99	78	6	MP:0003936
MousePheno	aminoaciduria	GGT2P GGT1 GGT3P GLDC	1.92e-05	29	78	4	MP:0003311
MousePheno	failure of copulatory plug deposition	GGT2P GGT1 GGT3P	1.95e-05	10	78	3	MP:0030983
MousePheno	seminal vesicle hypoplasia	GGT2P GGT1 GGT3P	1.95e-05	10	78	3	MP:0005148
MousePheno	abnormal circulating cysteine level	GGT2P GGT1 GGT3P	2.67e-05	11	78	3	MP:0030624
MousePheno	absent tertiary ovarian follicles	GGT2P GGT1 GGT3P	2.67e-05	11	78	3	MP:0011130
MousePheno	decreased circulating estradiol level	KDM5B GGT2P GGT1 GGT3P	5.73e-05	38	78	4	MP:0005181
MousePheno	priapism	GGT2P GGT1 GGT3P	5.82e-05	14	78	3	MP:0003415
MousePheno	decreased circulating estrogen level	KDM5B GGT2P GGT1 GGT3P	7.77e-05	41	78	4	MP:0003371
MousePheno	abnormal copulatory plug deposition	GGT2P GGT1 GGT3P	8.88e-05	16	78	3	MP:0030982
MousePheno	decreased spleen red pulp amount	GGT2P GGT1 GGT3P	8.88e-05	16	78	3	MP:0008477
MousePheno	failure of superovulation	GGT2P GGT1 GGT3P	1.28e-04	18	78	3	MP:0031422
MousePheno	abnormal penile erection	GGT2P GGT1 GGT3P	1.28e-04	18	78	3	MP:0001379
MousePheno	oocyte degeneration	GGT2P GGT1 GGT3P	1.28e-04	18	78	3	MP:0009093
MousePheno	increased circulating growth hormone level	GGT2P GGT1 GGT3P	1.52e-04	19	78	3	MP:0005123
MousePheno	abnormal copulation physiology	GGT2P GGT1 GGT3P	1.52e-04	19	78	3	MP:0031627
MousePheno	increased circulating iron level	FNIP2 LRP1B SLC7A2 TRIM56 ACSF3	1.52e-04	91	78	5	MP:0008810
MousePheno	small uterus	KDM5B CRTC1 GGT2P GGT1 GGT3P	1.60e-04	92	78	5	MP:0002637
MousePheno	increased circulating mineral level	FNIP2 DNAJB12 HECW1 LRP1B LEFTY2 SLC7A2 SEPSECS ZNF644 TRIM56 ACSF3 COASY HERC1	1.69e-04	626	78	12	MP:0014547
MousePheno	abnormal circulating estradiol level	KDM5B GGT2P GGT1 GGT3P	1.98e-04	52	78	4	MP:0005183
MousePheno	small vertebrae	GGT2P GGT1 GGT3P	2.38e-04	22	78	3	MP:0004610
MousePheno	aciduria	GGT2P GGT1 GGT3P GLDC	2.47e-04	55	78	4	MP:0010028
MousePheno	increased growth hormone level	GGT2P GGT1 GGT3P	2.73e-04	23	78	3	MP:0005137
MousePheno	uterus hypoplasia	GGT2P GGT1 GGT3P	2.73e-04	23	78	3	MP:0001121
MousePheno	abnormal circulating estrogen level	KDM5B GGT2P GGT1 GGT3P	2.83e-04	57	78	4	MP:0003369
MousePheno	disproportionate dwarf	HSPG2 GGT2P GGT1 GGT3P	2.83e-04	57	78	4	MP:0002427
MousePheno	increased mineral level	FNIP2 DNAJB12 HECW1 LRP1B LEFTY2 SLC7A2 SEPSECS ZNF644 TRIM56 ACSF3 COASY HERC1	3.08e-04	668	78	12	MP:0014535
MousePheno	abnormal copulation behavior	GGT2P GGT1 GGT3P	3.11e-04	24	78	3	MP:0009697
MousePheno	abnormal urine amino acid level	GGT2P GGT1 GGT3P GLDC	3.23e-04	59	78	4	MP:0011468
MousePheno	immotile sperm	GGT2P GGT1 GGT3P TBC1D20	3.23e-04	59	78	4	MP:0020869
MousePheno	decreased circulating gonadotropin level	CRTC1 GGT2P GGT1 GGT3P	3.45e-04	60	78	4	MP:0003363
MousePheno	abnormal uterus size	KDM5B CRTC1 GGT2P GGT1 GGT3P ZNF644	3.46e-04	168	78	6	MP:0004902
MousePheno	impaired ovarian folliculogenesis	WT1 GGT2P GGT1 GGT3P	3.68e-04	61	78	4	MP:0001129
MousePheno	female infertility	KDM5B CRTC1 STING1 PKD1L2 GGT2P GGT1 GGT3P ZSCAN21 CBFA2T2	4.48e-04	410	78	9	MP:0001926
MousePheno	abnormal superovulation	WT1 GGT2P GGT1 GGT3P	4.97e-04	66	78	4	MP:0009648
MousePheno	absent corpus luteum	CRTC1 GGT2P GGT1 GGT3P	4.97e-04	66	78	4	MP:0001134
MousePheno	abnormal long bone epiphyseal plate proliferative zone	HSPG2 GGT2P GGT1 GGT3P	5.57e-04	68	78	4	MP:0003662
MousePheno	absent frontal bone	HSPG2 TCOF1	6.34e-04	7	78	2	MP:0004376
MousePheno	increased iron level	FNIP2 LRP1B SLC7A2 TRIM56 ACSF3	6.38e-04	124	78	5	MP:0014541
MousePheno	abnormal amino acid derivative level	GGT2P GGT1 GGT3P GLDC ALDH1L2	6.61e-04	125	78	5	MP:0021145
MousePheno	anovulation	GGT2P GGT1 GGT3P	8.08e-04	33	78	3	MP:0008869
MousePheno	increased Ly6C low monocyte number	WAC HERC1	8.42e-04	8	78	2	MP:0013025
MousePheno	decreased circulating follicle stimulating hormone level	GGT2P GGT1 GGT3P	8.83e-04	34	78	3	MP:0002790
MousePheno	increased osteoclast cell number	HSPG2 GGT2P GGT1 GGT3P	8.92e-04	77	78	4	MP:0004984
MousePheno	accessory spleen	LEFTY2 B9D2	1.08e-03	9	78	2	MP:0003342
MousePheno	absent parietal bone	HSPG2 TCOF1	1.08e-03	9	78	2	MP:0004419
MousePheno	abnormal upper lip morphology	TCOF1 KIF7 GLDC	1.13e-03	37	78	3	MP:0012523
MousePheno	abnormal hypaxial muscle morphology	ASNSD1 WT1 KIF7 B9D2 TRIM55	1.14e-03	141	78	5	MP:0003358
MousePheno	decreased tertiary ovarian follicle number	GGT2P GGT1 GGT3P	1.32e-03	39	78	3	MP:0011129
MousePheno	abnormal limb morphology	ASNSD1 DNAJB12 HSPG2 TCOF1 DNAJC16 RIPK4 GGT2P GGT1 GGT3P KIF7 B9D2 SLC7A2 WNT16 TRIM55	1.50e-03	1028	78	14	MP:0002109
Domain	DEAD_ATP_HELICASE	DDX31 DDX27 DDX6 DDX28	2.09e-05	31	99	4	PS00039
Domain	RNA-helicase_DEAD-box_CS	DDX31 DDX27 DDX6 DDX28	2.70e-05	33	99	4	IPR000629
Domain	Q_MOTIF	DDX31 DDX27 DDX6 DDX28	4.29e-05	37	99	4	PS51195
Domain	RNA_helicase_DEAD_Q_motif	DDX31 DDX27 DDX6 DDX28	4.29e-05	37	99	4	IPR014014
Domain	IG	HSPG2 LRRC4B SIGLEC15 CILP2 LRIG1 HAPLN3 KIR2DL4 KIR3DL2 BTNL9	3.99e-04	421	99	9	SM00409
Domain	Ig_sub	HSPG2 LRRC4B SIGLEC15 CILP2 LRIG1 HAPLN3 KIR2DL4 KIR3DL2 BTNL9	3.99e-04	421	99	9	IPR003599
Domain	GGT_peptidase	GGT1 GGT3P	5.74e-04	7	99	2	IPR000101
Domain	G_glu_transpept	GGT1 GGT3P	5.74e-04	7	99	2	PF01019
Domain	G_GLU_TRANSPEPTIDASE	GGT1 GGT3P	5.74e-04	7	99	2	PS00462
Domain	DEAD/DEAH_box_helicase_dom	DDX31 DDX27 DDX6 DDX28	6.11e-04	73	99	4	IPR011545
Domain	DEAD	DDX31 DDX27 DDX6 DDX28	6.11e-04	73	99	4	PF00270
Domain	zf-RING_UBOX	TRIM54 TRIM56 TRIM55	7.67e-04	34	99	3	PF13445
Domain	Znf-RING_LisH	TRIM54 TRIM56 TRIM55	7.67e-04	34	99	3	IPR027370
Pathway	REACTOME_GLUTATHIONE_SYNTHESIS_AND_RECYCLING	GGT2P GGT1 GGT3P	7.11e-05	16	73	3	MM14680
Pathway	WP_EICOSANOID_SYNTHESIS	GGT2P GGT1 GGT3P	1.91e-04	22	73	3	MM15961
Pathway	WP_OXYLIPINS_PATHWAYS	GGT2P GGT1 GGT3P	2.49e-04	24	73	3	MM17249
Pathway	REACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX	GGT2P GGT1 GGT3P	2.82e-04	25	73	3	MM14858
Pathway	REACTOME_AFLATOXIN_ACTIVATION_AND_DETOXIFICATION	GGT2P GGT1 GGT3P	3.18e-04	26	73	3	MM15190
Pathway	WP_GLUTATHIONE_METABOLISM	GGT2P GGT1 GGT3P	3.56e-04	27	73	3	MM15908
Pubmed	Different gamma-glutamyl transpeptidase mRNAs are expressed in human liver and kidney.	GGT2P GGT1 GGT3P	2.31e-08	3	100	3	2573352
Pubmed	Lung lining fluid glutathione attenuates IL-13-induced asthma.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	18063838
Pubmed	Gamma-glutamyltranspeptidase knockout mice as a model for understanding the consequences of diminished glutathione on T cell-dependent immune responses.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	10940879
Pubmed	Cataract development in gamma-glutamyl transpeptidase-deficient mice.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	11095909
Pubmed	Expression of gamma-glutamyl transpeptidase in midgestation mouse yolk sac and mouse visceral yolk sac carcinoma cells.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	7641802
Pubmed	Phenotypic characterization of Ggt1(dwg/dwg) mice,a mouse model for hereditary γ-glutamyltransferase deficiency.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	23615310
Pubmed	The mouse skin carcinogenesis model.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	9627710
Pubmed	Gamma-glutamyl transpeptidase and its role in melanogenesis: redox reactions and regulation of tyrosinase.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	12453183
Pubmed	gamma-glutamyltranspeptidase-deficient knockout mice as a model to study the relationship between glutathione status, mitochondrial function, and cellular function.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	11003618
Pubmed	Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	10392451
Pubmed	Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of mouse kidney.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	2891746
Pubmed	Hyperoxia-induced lung injury in gamma-glutamyl transferase deficiency is associated with alterations in nitrosative and nitrative stress.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	19850887
Pubmed	Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	12810527
Pubmed	Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	8755578
Pubmed	Reproductive defects in gamma-glutamyl transpeptidase-deficient mice.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	11089562
Pubmed	Liver-Specific Overexpression of Gamma-Glutamyltransferase Ameliorates Insulin Sensitivity of Male C57BL/6 Mice.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	28660214
Pubmed	Bleomycin-induced pulmonary fibrosis is attenuated in gamma-glutamyl transpeptidase-deficient mice.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	12468440
Pubmed	N-acetyl-cysteine prevents age-related hearing loss and the progressive loss of inner hair cells in γ-glutamyl transferase 1 deficient mice.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	26977590
Pubmed	Gamma-glutamyl transferase deficiency results in lung oxidant stress in normoxia.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	12225953
Pubmed	Identification of a sixth promoter that directs the transcription of gamma-glutamyl transpeptidase type III RNA in mouse.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	7775425
Pubmed	Cloning of cDNA and genomic structure of the mouse gamma-glutamyl transpeptidase-encoding gene.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	8566783
Pubmed	Therapeutic Effect of GGsTop, Selective Gamma-glutamyl Transpeptidase Inhibitor, on a Mouse Model of 5-Fluorouracil-induced Oral Mucositis.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	30591459
Pubmed	Mice with genetic gamma-glutamyl transpeptidase deficiency exhibit glutathionuria, severe growth failure, reduced life spans, and infertility.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	9139708
Pubmed	Analysis of site-specific glycosylation of renal and hepatic γ-glutamyl transpeptidase from normal human tissue.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	20622017
Pubmed	Accelerated methylmercury elimination in gamma-glutamyl transpeptidase-deficient mice.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	9546365
Pubmed	In vivo reversal of glutathione deficiency and susceptibility to in vivo dexamethasone-induced apoptosis by N-acetylcysteine and L-2-oxothiazolidine-4-carboxylic acid, but not ascorbic acid, in thymocytes from gamma-glutamyltranspeptidase-deficient knockout mice.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	11795900
Pubmed	gamma-Glutamyl transpeptidase. What does the organization and expression of a multipromoter gene tell us about its functions?	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	7485380
Pubmed	Accumulation of DNA damage in the organs of mice deficient in gamma-glutamyltranspeptidase.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	10751614
Pubmed	Type VI RNA is the major gamma-glutamyl transpeptidase RNA in the mouse small intestine.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	7523374
Pubmed	Cardio-reno-hepatic interactions in acute heart failure: the role of γ-glutamyl transferase.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	24698228
Pubmed	Inhibiting lung lining fluid glutathione metabolism with GGsTop as a novel treatment for asthma.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	25132819
Pubmed	Characterization of the dwg mutations: dwg and dwg(Bayer) are new mutant alleles of the Ggt1 gene.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	19760322
Pubmed	gamma-Glutamyl transferase (GGT) deficiency in the GGTenu1 mouse results from a single point mutation that leads to a stop codon in the first coding exon of GGT mRNA.	GGT2P GGT1 GGT3P	2.30e-07	5	100	3	10474818
Pubmed	Gamma-glutamyltranspeptidase stimulates receptor activator of nuclear factor-kappaB ligand expression independent of its enzymatic activity and serves as a pathological bone-resorbing factor.	GGT2P GGT1 GGT3P	4.58e-07	6	100	3	14634009
Pubmed	Overexpression of gamma-glutamyltransferase in transgenic mice accelerates bone resorption and causes osteoporosis.	GGT2P GGT1 GGT3P	4.58e-07	6	100	3	17363454
Pubmed	Six mRNAs with different 5' ends are encoded by a single gamma-glutamyltransferase gene in mouse.	GGT2P GGT1 GGT3P	4.58e-07	6	100	3	8101000
Pubmed	Four distinct membrane-bound dipeptidase RNAs are differentially expressed and show discordant regulation with gamma-glutamyl transpeptidase.	GGT2P GGT1 GGT3P	4.58e-07	6	100	3	8663190
Pubmed	Mapping of human gamma-glutamyl transpeptidase genes on chromosome 22 and other human autosomes.	GGT2P GGT1 GGT3P	4.58e-07	6	100	3	8104871
Pubmed	Disruption of gamma-glutamyl leukotrienase results in disruption of leukotriene D(4) synthesis in vivo and attenuation of the acute inflammatory response.	GGT2P GGT1 GGT3P	4.58e-07	6	100	3	11463821
Pubmed	Effect of atorvastatin on the expression of gamma-glutamyl transferase in aortic atherosclerotic plaques of apolipoprotein E-knockout mice.	GGT2P GGT1 GGT3P	4.58e-07	6	100	3	25326709
Pubmed	Gamma-glutamyl leukotrienase, a novel endothelial membrane protein, is specifically responsible for leukotriene D(4) formation in vivo.	GGT2P GGT1 GGT3P	4.58e-07	6	100	3	12163373
Pubmed	Ablation of Mrds1/Ofcc1 induces hyper-γ-glutamyl transpeptidasemia without abnormal head development and schizophrenia-relevant behaviors in mice.	GGT2P GGT1 GGT3P	4.58e-07	6	100	3	22242126
Pubmed	γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis.	GGT2P GGT1 GGT3P	8.01e-07	7	100	3	27775020
Pubmed	Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.	GGT2P GGT1 GGT3P	8.01e-07	7	100	3	32284594
Pubmed	Defective epidermal growth factor gene expression in mice with polycystic kidney disease.	GGT2P GGT1 GGT3P	8.01e-07	7	100	3	1968405
Pubmed	m6A eraser FTO modulates autophagy by targeting SQSTM1/P62 in the prevention of canagliflozin against renal fibrosis.	GGT2P GGT1 GGT3P	8.01e-07	7	100	3	36685533
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	HSPG2 HECW1 MATK TRIM54 NELL2 VARS1	1.23e-06	118	100	6	21078624
Pubmed	Renalase regulates renal dopamine and phosphate metabolism.	GGT2P GGT1 GGT3P	2.73e-06	10	100	3	23863468
Pubmed	Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.	WT1 GGT2P GGT1 GGT3P	4.41e-06	38	100	4	27820600
Pubmed	Gamma glutamyl transferase activity is independently associated with oxidative stress rather than SYNTAX score.	GGT2P GGT1	8.18e-06	2	100	2	25180444
Pubmed	Association between serum γ-glutamyltranspeptidase and atherosclerosis: a population-based cross-sectional study.	GGT2P GGT1	8.18e-06	2	100	2	25280803
Pubmed	Clinical application value of hepatitis B virus basal core promoter 1762/1764 and GGTII and GGT in patients with HBV-DNA-positive primary liver cancer.	GGT2P GGT1	8.18e-06	2	100	2	37904480
Pubmed	STING Contributes to Host Defense Against Staphylococcus aureus Pneumonia Through Suppressing Necroptosis.	STING1 MLKL	8.18e-06	2	100	2	34135886
Pubmed	Human GGT2 does not autocleave into a functional enzyme: A cautionary tale for interpretation of microarray data on redox signaling.	GGT2P GGT1	8.18e-06	2	100	2	23682772
Pubmed	Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.	TRIM54 TRIM55	8.18e-06	2	100	2	27493870
Pubmed	Inhibition of KDM5B participates in immune microenvironment remodeling in pancreatic cancer by inducing STING expression.	KDM5B STING1	8.18e-06	2	100	2	38163400
Pubmed	The human gamma-glutamyltransferase gene family.	GGT2P GGT1 GGT3P	8.20e-06	14	100	3	18357469
Pubmed	Gene dosage in the developing and adult brain in a mouse model of 22q11 deletion syndrome.	GGT2P GGT1 GGT3P	1.82e-05	18	100	3	17097888
Pubmed	Relationship between PIWIL4-Mediated H3K4me2 Demethylation and piRNA-Dependent DNA Methylation.	KDM5B KDM1A	2.45e-05	3	100	2	30304676
Pubmed	DNA methylation maintains allele-specific KIR gene expression in human natural killer cells.	KIR2DL4 KIR3DL2	2.45e-05	3	100	2	12538663
Pubmed	Hypoxia Promotes Resistance to EGFR Inhibition in NSCLC Cells via the Histone Demethylases, LSD1 and PLU-1.	KDM5B KDM1A	2.45e-05	3	100	2	29934325
Pubmed	Killer cell immunoglobulin-like receptor allele discrimination by high-resolution melting.	KIR2DL4 KIR3DL2	2.45e-05	3	100	2	19589363
Pubmed	The characteristics of allelic polymorphism in killer-immunoglobulin-like receptor framework genes in African Americans.	KIR2DL4 KIR3DL2	2.45e-05	3	100	2	21607693
Pubmed	The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA.	STING1 TRIM56	2.45e-05	3	100	2	21074459
Pubmed	Transport of asymmetric dimethylarginine (ADMA) by cationic amino acid transporter 2 (CAT2), organic cation transporter 2 (OCT2) and multidrug and toxin extrusion protein 1 (MATE1).	GIT2 SLC7A2	4.89e-05	4	100	2	23864433
Pubmed	Hierarchy of clinical manifestations in SAVI N153S and V154M mouse models.	STING1 MLKL	4.89e-05	4	100	2	30944222
Pubmed	The zinc finger proteins ZNF644 and WIZ regulate the G9a/GLP complex for gene repression.	WIZ ZNF644	4.89e-05	4	100	2	25789554
Pubmed	Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain.	TRIM54 TRIM55	4.89e-05	4	100	2	11243782
Pubmed	Wnt3a-dependent and -independent protein interaction networks of chromatin-bound β-catenin in mouse embryonic stem cells.	LEFTY2 KDM1A	4.89e-05	4	100	2	23592333
Pubmed	[Differential expression levels of killer immunoglobin-like receptor genotype in patients with hematological malignancies between high-risk and standard-risk groups].	KIR2DL4 KIR3DL2	4.89e-05	4	100	2	18718052
Pubmed	Hepatoblast-like cells enriched from mouse embryonic stem cells in medium without glucose, pyruvate, arginine, and tyrosine.	GGT2P GGT1 GGT3P	6.42e-05	27	100	3	18478268
Pubmed	Cell-surface proteomics identifies lineage-specific markers of embryo-derived stem cells.	GGT2P GGT1 GGT3P	7.98e-05	29	100	3	22424930
Pubmed	Cloning and nucleotide sequence of human gamma-glutamyl transpeptidase.	GGT1 GGT3P	8.14e-05	5	100	2	2904146
Pubmed	Expression of multiple gamma-glutamyltransferase genes in man.	GGT1 GGT3P	8.14e-05	5	100	2	7906515
Pubmed	The Sertoli cell expressed gene secernin-1 (Scrn1) is dispensable for male fertility in the mouse.	WT1 SCRN2	8.14e-05	5	100	2	33442887
Pubmed	A TRAF3-NIK module differentially regulates DNA vs RNA pathways in innate immune signaling.	MAP3K14 STING1	8.14e-05	5	100	2	30018345
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	PUS3 TCOF1 WDR7 DNAJC16 INPP5B RNF213 RYR2 FAT1 WIZ RPL3	8.29e-05	777	100	10	35844135
Pubmed	UBXN3B positively regulates STING-mediated antiviral immune responses.	STING1 TRIM56	1.22e-04	6	100	2	29899553
Pubmed	Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-β Synthesis Induced by Lipopolysaccharide.	STING1 MLKL	1.22e-04	6	100	2	28461567
Pubmed	Metformin Combining PD-1 Inhibitor Enhanced Anti-Tumor Efficacy in STK11 Mutant Lung Cancer Through AXIN-1-Dependent Inhibition of STING Ubiquitination.	STING1 TRIM56	1.22e-04	6	100	2	35281267
Pubmed	Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4.	KDM5B KDM1A	1.22e-04	6	100	2	20228790
Pubmed	The ZNF217 oncogene is a candidate organizer of repressive histone modifiers.	KDM5B KDM1A	1.22e-04	6	100	2	19242095
Pubmed	E3-ligase knock down revealed differential titin degradation by autopagy and the ubiquitin proteasome system.	TRIM54 TRIM55	1.22e-04	6	100	2	34702928
Pubmed	The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.	WT1 GGT2P GGT1 GGT3P	1.68e-04	95	100	4	20843830
Pubmed	Identification of the mouse killer immunoglobulin-like receptor-like (Kirl) gene family mapping to chromosome X.	KIR2DL4 KIR3DL2	1.70e-04	7	100	2	12618911
Pubmed	Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1.	TRIM54 TRIM55	1.70e-04	7	100	2	11927605
Pubmed	Expression of a killer cell receptor-like gene in plastic regions of the central nervous system.	KIR2DL4 KIR3DL2	1.70e-04	7	100	2	15748957
Pubmed	Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis.	KIR2DL4 KIR3DL2	1.70e-04	7	100	2	26928464
Pubmed	The diversity of KIR gene in Chinese Northern Han population and the impact of donor KIR and patient HLA genotypes on outcome following HLA-identical sibling allogeneic hematopoietic stem cell transplantation for hematological malignancy in Chinese people.	KIR2DL4 KIR3DL2	1.70e-04	7	100	2	18347914
Pubmed	A population-based cohort study of KIR genes and genotypes in relation to cervical intraepithelial neoplasia.	KIR2DL4 KIR3DL2	2.27e-04	8	100	2	15730517
Pubmed	Human diversity in killer cell inhibitory receptor genes.	KIR2DL4 KIR3DL2	2.27e-04	8	100	2	9430221
Pubmed	The DNA sequence of human chromosome 22.	KREMEN1 GGT2P GGT1 MYO18B MAPK11 RPL3	2.37e-04	300	100	6	10591208
Pubmed	Mouse models of ocular diseases.	GGT2P GGT1 GGT3P	2.80e-04	44	100	3	16332269
Pubmed	Polymorphisms of killer cell immunoglobulin-like receptor gene: possible association with susceptibility to or clearance of hepatitis B virus infection in Chinese Han population.	KIR2DL4 KIR3DL2	2.91e-04	9	100	2	18074414
Pubmed	A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.	HECW1 CRTC1	2.91e-04	9	100	2	24121790
Pubmed	Distribution of KIR genes in the Czech population.	KIR2DL4 KIR3DL2	2.91e-04	9	100	2	18186800
Pubmed	Developmental regulation of MURF ubiquitin ligases and autophagy proteins nbr1, p62/SQSTM1 and LC3 during cardiac myofibril assembly and turnover.	TRIM54 TRIM55	2.91e-04	9	100	2	21185285
Pubmed	A comprehensive analysis of 22q11 gene expression in the developing and adult brain.	GGT2P GGT1 GGT3P	3.00e-04	45	100	3	14614146
Pubmed	Mapping the Genetic Landscape of Human Cells.	TCOF1 WDR7 NDUFB2 KIF14 METTL17 RPL3 KDM1A	3.34e-04	451	100	7	30033366
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	ZNF628 KIF7 FBXW8 WIZ GLDC TRIM56	3.40e-04	321	100	6	32098917
Interaction	CACNA1A interactions	HSPG2 KDM5B HECW1 WDR7 MATK STING1 NELL2 VARS1	1.52e-07	123	98	8	int:CACNA1A
Interaction	NUF2 interactions	INPP5B GIT2 STING1 DDX6 KIF7 METTL17 NPAS1	2.32e-06	123	98	7	int:NUF2
Interaction	POLRMT interactions	MAP3K14 APBA1 NELL2 GLDC KIF14 METTL17 DDX28 KDM1A	8.88e-06	211	98	8	int:POLRMT
Interaction	FBLN2 interactions	HSPG2 ZNF142 ZNF628 ZNF696 ZSCAN21	1.73e-05	66	98	5	int:FBLN2
Interaction	C8orf74 interactions	TRIM54 TRIM55 KDM1A	3.08e-05	13	98	3	int:C8orf74
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF628 ZNF549 LRRC4B SPRED3 B9D2 CPT1C KIR2DL4 ZNF543 KIR3DL2 NPAS1	2.81e-04	1192	100	10	chr19q13
GeneFamily	CD molecules\|Gamma-glutamyltransferases	GGT2P GGT1 GGT3P	1.98e-05	13	76	3	564
GeneFamily	DEAD-box helicases	DDX31 DDX27 DDX6 DDX28	2.86e-05	42	76	4	499
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF142 ZNF555 ZNF628 ZNF549 WT1 ZNF696 WIZ ZSCAN21 ZNF543 ZNF646	8.19e-04	718	76	10	28
GeneFamily	CD molecules\|Killer cell immunoglobulin like receptors	KIR2DL4 KIR3DL2	2.55e-03	18	76	2	620
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM5B KDM1A	4.53e-03	24	76	2	485
GeneFamily	WD repeat domain containing	WDR7 CDC20B FBXW8 DCAF11 HERC1	4.92e-03	262	76	5	362
GeneFamily	Ring finger proteins	TRIM54 RNF213 RNF113B TRIM56 TRIM55	6.02e-03	275	76	5	58
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM54 TRIM56 TRIM55	7.49e-03	95	76	3	59
GeneFamily	ArfGAPs	GIT2 ADAP2	8.46e-03	33	76	2	395
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSPG2 ZNF555 ZNF549 ZNF696 FAT1 NPAS1	2.29e-06	169	100	6	2833a8a7094e4d407eb923f2bc59b9b112c6bae4
ToppCell	10x3'2.3-week_14-16-Lymphocytic_NK-T_NK-ILC_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PHYKPL HECW1 ABCB5 DOK7 CBFA2T2 DCAF11	3.29e-06	180	100	6	27672ac6a02172a31851f18decb9acffa8f5a703
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 PKD1L2 LRP1B RYR2 FAT1 EPHA10	3.74e-06	184	100	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 PKD1L2 LRP1B RYR2 FAT1 EPHA10	3.74e-06	184	100	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 PKD1L2 LRP1B RYR2 FAT1 EPHA10	3.74e-06	184	100	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOK7 TRIM54 RYR2 CILP2 TRIM55 MYO18B	3.98e-06	186	100	6	337f768cc43db2db96ba6495b076006b1a5b0331
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOK7 TRIM54 RYR2 CILP2 TRIM55 MYO18B	3.98e-06	186	100	6	e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM54 RYR2 ASB18 CILP2 TRIM55 MYO18B	4.36e-06	189	100	6	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM54 RYR2 ASB18 CILP2 TRIM55 MYO18B	4.36e-06	189	100	6	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	FNIP2 RYR2 SLC7A2 FAT1 TRIM55 MYO18B	4.49e-06	190	100	6	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	AT1-AT2_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	KDM5B ASB18 FAT1 WIZ EPHA10	2.88e-05	158	100	5	3bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCell	Bac-SEP-Lymphocyte-T_NK-NK_CD56bright\|Bac-SEP / Disease, Lineage and Cell Type	MATK ABCB5 TRIM54 HAPLN3 KIR2DL4	2.88e-05	158	100	5	20411158d71699a80f6c1566791af89dea0e1875
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-TRGV5/7_gdT\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF628 MATK TRIM54 HERC1 KIR2DL4	3.76e-05	167	100	5	18e336faa2d2429ab49d1c6ae9bbf9923d74aa8d
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZNF142 RIPK4 B9D2 LRIG1 ZSCAN21	3.87e-05	168	100	5	9e7b4b9b977e90e083f5164013e79df8bc2d492e
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHYKPL MATK TRIM54 ADAMTSL5 KIR2DL4	3.87e-05	168	100	5	2765d98f0b7f6861d662937535e051d41dba3500
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM54 RYR2 ALDH1L2 TRIM55 MYO18B	4.32e-05	172	100	5	ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM54 RYR2 ALDH1L2 TRIM55 MYO18B	4.32e-05	172	100	5	bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCell	Int-URO-Lymphocyte-T_NK-NK_CD56bright\|Int-URO / Disease, Lineage and Cell Type	MATK CDC20B TRIM54 KIR2DL4 RPL3	4.57e-05	174	100	5	93c7acd5941a5f235ec4c57461f78ee2871e7336
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRIM54 RYR2 ASB18 TRIM55 MYO18B	4.82e-05	176	100	5	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRIM54 RYR2 ASB18 TRIM55 MYO18B	5.51e-05	181	100	5	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DOK7 ZNF696 FAT1 ADAMTSL5 CBFA2T2	5.80e-05	183	100	5	bbf27d2f4369031fadacacd6c432c06b1ec5abdb
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_CD56bright\|COVID-19_Mild / Disease group, lineage and cell class	MATK DOK7 TRIM54 HAPLN3 KIR2DL4	5.96e-05	184	100	5	f67308228bb6a5d624279fbb04db25a2f4087c9b
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRIM54 RYR2 ASB18 TRIM55 MYO18B	5.96e-05	184	100	5	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MATK DOK7 TRIM54 HAPLN3 KIR2DL4	6.11e-05	185	100	5	3a046c948524e5d0e986cd645e318d6930d7e0ee
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	MATK DOK7 TRIM54 HAPLN3 KIR2DL4	6.11e-05	185	100	5	71d1a771026d9fa3528d46ac3d11353e396f2d87
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MATK DOK7 TRIM54 HAPLN3 KIR2DL4	6.11e-05	185	100	5	37b48218dd523049b57b13eb9cdb34e106cf91ea
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MATK DOK7 TRIM54 HAPLN3 KIR2DL4	6.11e-05	185	100	5	df5d2309d19ac8d5e429afa785d0a480e75a8f9e
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM54 RYR2 CILP2 TRIM55 MYO18B	6.59e-05	188	100	5	90dc0e15798d0b984518ad58c7e416e30aff687a
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM54 RYR2 CILP2 TRIM55 MYO18B	6.59e-05	188	100	5	f63dfd076ced81013918363282ae25cbbd8948ae
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM54 RYR2 CILP2 TRIM55 MYO18B	6.59e-05	188	100	5	0554d542149cef654ff1e5e32dfbffd8990b52bd
ToppCell	facs-Heart-LA/RA-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM54 RYR2 CILP2 TRIM55 MYO18B	6.76e-05	189	100	5	a08b2d0fa35ffa510050ecffdc68e1b79bbe1632
ToppCell	facs-Heart-LA/RA\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM54 RYR2 CILP2 TRIM55 MYO18B	6.76e-05	189	100	5	efa913d9c16fc32166b484d92b6449e8a0c59e03
ToppCell	(3)_MNP-(3)_DC_activated\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	MAP3K14 NELL2 HAPLN3 MYO18B MAPK11	7.11e-05	191	100	5	0353bf797c4ef237b9bb82460c173c7d03cb8883
ToppCell	facs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM54 RYR2 ASB18 TRIM55 MYO18B	7.11e-05	191	100	5	543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCell	facs-Heart-LV-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM54 RYR2 ASB18 TRIM55 MYO18B	7.11e-05	191	100	5	9d7d680da3979e256191b534ebd14c5383e0cf93
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	FNIP2 TRIM54 RYR2 ASB18 MYO18B	7.46e-05	193	100	5	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	Mild-CD8+_T\|World / Disease group and Cell class	MATK NELL2 HERC1 KIR2DL4 KIR3DL2	7.65e-05	194	100	5	d64c2efb482bcdef9240977eae1023c4191286e7
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM54 LRRC4B RYR2 CILP2 MYO18B	8.03e-05	196	100	5	a582130862bee76c0385156a333bfdfc75cf218b
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM54 LRRC4B RYR2 CILP2 MYO18B	8.03e-05	196	100	5	fba52a4b82086dbae9a55038bf44c4539be926f5
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HECW1 RYR2 NELL2 GLDC MYO18B	8.42e-05	198	100	5	d1827e3707b929e3a3562989a0c11537d344e164
ToppCell	Transverse-T_cell-Tfh\|Transverse / Region, Cell class and subclass	APBA1 SYNGAP1 NELL2 LRIG1 ZNF543	8.62e-05	199	100	5	cbef8f95edf2e86e16c448a76068d7ed8f6b7748
ToppCell	Transverse-(1)_T_cell-(16)_Tfh\|Transverse / shred on region, Cell_type, and subtype	APBA1 SYNGAP1 NELL2 LRIG1 ZNF543	8.62e-05	199	100	5	aa31e26d48066f865ca33251a33a28934c0a7a44
ToppCell	Transverse-T_cell-gd_T\|T_cell / Region, Cell class and subclass	PHYKPL MATK DOK7 KIR2DL4 KIR3DL2	8.62e-05	199	100	5	8baea162803cea7d72dff5866a0eebfcf2e5dcd6
ToppCell	Control-Control-Lymphocyte-T/NK-NK_CD56bright\|Control / Disease, condition lineage and cell class	MATK TRIM54 HAPLN3 KIR2DL4 RPL3	8.83e-05	200	100	5	d843fe0781c7699afead4429c526441c6fdb8cba
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_CD56bright\|COVID-19_Mild / Disease, condition lineage and cell class	MATK DOK7 TRIM54 HAPLN3 KIR2DL4	8.83e-05	200	100	5	bb21e26a8b7cbceddb1ab5163a223a186d914da4
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-T-T_CD8-gdT\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MATK DOK7 TRIM54 WNT16 KIR2DL4	8.83e-05	200	100	5	f62e594b076fdfa63a425f424da204203777e7c9
ToppCell	severe-NK\|World / disease stage, cell group and cell class	MATK NDUFB2 DDX6 KIR2DL4 KIR3DL2	8.83e-05	200	100	5	320cb0d79adaa1b43d90d027a876cd74f8b55ec3
Disease	aflatoxins-related hepatocellular carcinoma (biomarker_via_orthology)	GGT2P GGT1 GGT3P	1.09e-06	7	94	3	DOID:5022 (biomarker_via_orthology)
Disease	alcohol dependence (biomarker_via_orthology)	GGT2P GGT1 GGT3P	1.73e-06	8	94	3	DOID:0050741 (biomarker_via_orthology)
Disease	Global developmental delay	ZNF142 PUS3 DDX6 TBC1D20 KDM1A	6.87e-05	133	94	5	C0557874
Disease	response to angiotensin-converting enzyme inhibitor, Cough	DNAJC16 ABCB5 PKD1L2	4.30e-04	46	94	3	EFO_0005325, HP_0012735
Disease	Intellectual Disability	ZNF142 PUS3 DDX6 WAC KIF7 TBC1D20 SYNGAP1	5.76e-04	447	94	7	C3714756
Disease	congenital diaphragmatic hernia (implicated_via_orthology)	WT1 KIF7	6.49e-04	12	94	2	DOID:3827 (implicated_via_orthology)
Disease	killer cell immunoglobulin-like receptor 2DL4 measurement	KIR2DL4 KIR3DL2	6.49e-04	12	94	2	EFO_0008197
Disease	esophageal adenocarcinoma	HECW1 CRTC1	1.49e-03	18	94	2	EFO_0000478
Disease	Meckel syndrome type 1	B9D2 KIF14	1.49e-03	18	94	2	C3714506
Disease	Paroxysmal atrial fibrillation	HSPG2 LRIG1 HERC1 MYO18B	1.58e-03	156	94	4	C0235480
Disease	familial atrial fibrillation	HSPG2 LRIG1 HERC1 MYO18B	1.58e-03	156	94	4	C3468561
Disease	Persistent atrial fibrillation	HSPG2 LRIG1 HERC1 MYO18B	1.58e-03	156	94	4	C2585653
Disease	Atrial Fibrillation	HSPG2 LRIG1 HERC1 MYO18B	1.74e-03	160	94	4	C0004238
Disease	FEV change measurement, response to zileuton	GLT1D1 SLC7A2	2.87e-03	25	94	2	EFO_0005921, EFO_0007676

Protein segments in the cluster

Peptide	Gene	Start	Entry
ETYLHRIGRSGRFGH	DDX6	416	P26196
AGRHYWEVHVGRRSR	BTNL9	381	Q6UXG8
DIRALNVRHYRDHIG	ABCB5	451	Q2M3G0
EVYSHLRKEGHRVVG	ALDH1L2	36	Q3SY69
VSRYEGGREHVAHLL	ORM2	106	P19652
YARQGGHHELAERLV	GIT2	206	Q14161
RIALVDQHGRHTYRE	ACSF3	56	Q4G176
YGIRHSLEGHLRDEN	SLC7A2	601	P52569
HYVHRVGRTARAGRA	DDX27	546	Q96GQ7
LRLARHYTGHQDVVV	PHYKPL	121	Q8IUZ5
HGLQITYRRDGHTRN	ADAP2	196	Q9NPF8
HGRLLAVTHGLRAYD	HSPG2	16	P98160
RGGHVALQCHYRRGF	KIR3DL2	41	P43630
GYKVIHVTGRLRAHA	NPAS1	266	Q99742
ARGTDYSILEIHHGR	FAT1	3871	Q14517
GEIRGYELAHQRHGR	GGT3P	136	A6NGU5
VLRHGDRVILGGDHY	KIF14	881	Q15058
RGLKYIHSAGIIHRD	MAPK11	136	Q15759
LRIPHVGRGRYEFHS	LBP	66	P18428
VGRGRYEFHSLNIHS	LBP	71	P18428
GTHRKIVYSGRELNH	LRP1B	726	Q9NZR2
SFGRDVIHYRVLHRD	MATK	161	P42679
GLRHRSFGDYQGRVH	HAPLN3	106	Q96S86
ILHLRQVTFGHEGRY	LRIG1	561	Q96JA1
LESSGHRNEVRLHYR	NELL2	116	Q99435
RHAIGDRVVSYTLGR	HECW1	311	Q76N89
LDEHARLYLGRGAHV	ASB18	231	Q6ZVZ8
GRLHHYQDGIRAAKR	HERC1	1701	Q15751
FTTHRRHRGLIRAYE	FBXW8	546	Q8N3Y1
EVRDRHHSLGLNGGY	CBFA2T2	316	O43439
YRGHGVLHTLIRCRF	DCAF11	431	Q8TEB1
YIHRAGRVGRVGSEV	DDX28	481	Q9NUL7
GVVHAGYERRLAHHL	DNAJC16	196	Q9Y2G8
RVTLGRDRHFGFHVV	KIF7	46	Q2M1P5
LDGYTHRVLARFHGR	KREMEN1	271	Q96MU8
AVGSHIRGHYERILN	KDM5B	166	Q9UGL1
YVHRGLAARHVLVSS	EPHA10	766	Q5JZY3
EYIHRIGRTARIGCH	DDX31	611	Q9H8H2
GFRYTVRAVHRLLEH	FOXRED2	401	Q8IWF2
LGAARGLYRLHHSEA	MLKL	311	Q8NB16
TRGRAHRLLHYCGSD	ADAMTSL5	366	Q6ZMM2
HYLVTVYTGHRRGAA	PKD1L2	1391	Q7Z442
GIARHLHAVIRYSVA	KIR2DL4	236	Q99706
RAGNAVHALLLYRHR	CPT1C	271	Q8TCG5
YVENGRVISDHRARH	FRMD1	146	Q8N878
RVHSYLERHGLINFG	KDM1A	251	O60341
ALHLYRGGRLLQGHR	GLT1D1	61	Q96MS3
RHHGLVDRVYRERGR	CRTC1	96	Q6UUV9
RAAVHAGVVRNHGGY	CRISPLD1	446	Q9H336
EYLRGHTRVHVKELG	FNIP2	1071	Q9P278
GHIHRRVTDHLGVVY	DNAJB12	281	Q9NXW2
HYVGRHQRGRALEDL	APBA1	46	Q02410
HVRAQYVVLLRRSHG	LEFTY2	56	O00292
AGYSRHRVRFQSHGL	ASNSD1	501	Q9NWL6
GSRLGRVYHHDVRVA	CDC20B	331	Q86Y33
LGLVRYRLEHGGQEH	INPP5B	36	P32019
DARIRYALGEVHRFH	DOK7	101	Q18PE1
RYRLHTAAGGTVHLE	B9D2	146	Q9BPU9
QRRTVHYEGGAVSVH	RYR2	256	Q92736
QHAVLTARRHGRDLY	METTL17	411	Q9H7H0
GEIRGYELAHQRHGR	GGT2P	136	P36268
HGSYRVRISVLHDGT	LRRC4B	406	Q9NT99
EGLEYLHSRRILHGD	MAP3K14	501	Q99558
FREVYLHAIVRDAHG	VARS1	846	P26640
LAEELRHIHSRYRGS	STING1	66	Q86WV6
DFSAHGRRHVALRIA	PUS3	56	Q9BZE2
HDRYESRHGVRLHVT	SIGLEC15	151	Q6ZMC9
AHYGRGRVVLAAHEC	TCAF2	261	A6NFQ2
HHLLRAGYVRAAREV	TCOF1	16	Q13428
EALRGREHDHIYRGI	RNF113B	136	Q8IZP6
VARAGQKGYHHRTEI	RPL3	266	P39023
QVDRRHTLYRGHQAA	SCRN2	351	Q96FV2
VHTHRVRERDGGTSY	WAC	81	Q9BTA9
RGHLNRVGVSYNVRH	WIZ	721	O95785
LHLAAQRGHYRVARI	RIPK4	656	P57078
TLLDRRAHGYGAHLE	CILP2	331	Q8IUL8
RAHGYGAHLELRGLR	CILP2	336	Q8IUL8
LYAGADVHRHLDVRI	COASY	71	Q13057
HYTRDLGHDRVLVEG	RNF213	421	Q63HN8
CRHEVVLDRHGVYGL	TRIM54	81	Q9BYV2
TYRDREADRHIHGIA	PRO0255	51	Q9UI72
GSDGAYRLELRHELH	nan	136	Q6ZTK2
CRHEVVLDRHGVYGL	TRIM55	81	Q9BYV6
YLQSFRRHERIHTGE	ZNF555	351	Q8NEP9
IHSYDRIRHQRVHTG	ZNF549	371	Q6P9A3
RIRHQRVHTGEGAYQ	ZNF549	376	Q6P9A3
GKGSLIRHYRIHTGE	ZSCAN21	371	Q9Y5A6
GEHEYHLGRSRRKSV	SYNGAP1	96	Q96PV0
GHYVIHGERLRDQKT	SPRED3	46	Q2MJR0
VRHAGGGVHIEPRYR	NDUFB2	31	O95178
KHRRTHTGERLYACG	ZNF696	226	Q9H7X3
FRTAARLEGHGRVHA	ZNF646	1741	O15015
YRIHTHGVFRGIQDV	WT1	286	P19544
GRGYNTHVVRHVERC	WNT16	326	Q9UBV4
GFHILEALRLHRTGY	MYO18B	1246	Q8IUG5
HVRGHLHRAGLSYEA	ZNF644	981	Q9H582
LHRAGLSYEARHVVS	ZNF644	986	Q9H582
RDRPGFIRHYIIHTG	ZNF543	321	Q08ER8
SALVARRHYRFIHGI	SEPSECS	81	Q9HD40
RRHYRFIHGIGRSGD	SEPSECS	86	Q9HD40
GHVLSDFRHVVRLYD	TBC1D20	226	Q96BZ9
RRYRLEAHQSRHTGI	ZNF142	1211	P52746
YYERNHRIAVGARHG	WDR7	1361	Q9Y4E6
HRIAVGARHGSVALY	WDR7	1366	Q9Y4E6
THTHRVVDLVGYRAG	TRIM56	141	Q9BRZ2
SSGLRYHLRDHTGER	ZNF628	466	Q5EBL2
GEIRGYELAHQRHGR	GGT1	136	P19440
AIYHGSHGLEHIARR	GLDC	396	P23378