Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H4K20me methyltransferase activity	KMT5B KMT5C	7.03e-05	4	69	2	GO:0140941
GeneOntologyMolecularFunction	sulfur compound binding	AMBP THBS2 KMT5B ENPP1 KMT5C DMBT1 RYR2	1.24e-04	323	69	7	GO:1901681
GeneOntologyMolecularFunction	histone modifying activity	RSBN1 KMT5B KMT5C METTL8 CHEK1 PADI2	1.40e-04	229	69	6	GO:0140993
GeneOntologyMolecularFunction	histone H4K20 monomethyltransferase activity	KMT5B KMT5C	1.75e-04	6	69	2	GO:0140944
GeneOntologyMolecularFunction	calcium ion binding	CACNA1B PRSS1 PRSS2 THBD THBS2 ENPP1 TLL1 PPP2R3B PADI2 RYR2	2.39e-04	749	69	10	GO:0005509
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	CACNA1A CACNA1B	4.17e-04	9	69	2	GO:0099511
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	CACNA1A CACNA1B	4.17e-04	9	69	2	GO:0099626
GeneOntologyMolecularFunction	histone H4K20 methyltransferase activity	KMT5B KMT5C	5.20e-04	10	69	2	GO:0042799
GeneOntologyMolecularFunction	carbohydrate binding	AMBP CRYBG2 IGF2R MANBA ENPP1 NECTIN1	7.04e-04	310	69	6	GO:0030246
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1A CACNA1B	1.04e-03	14	69	2	GO:0008331
GeneOntologyBiologicalProcess	synapse assembly	CACNA1A THBS2 MYCBP2 NECTIN1 ADGRF1 DCX DCLK1	7.55e-05	308	69	7	GO:0007416
GeneOntologyBiologicalProcess	cell junction assembly	CACNA1A THBS2 MYCBP2 NECTIN1 NFASC PEAK1 ADGRF1 DCX DCLK1	1.13e-04	569	69	9	GO:0034329
GeneOntologyBiologicalProcess	peptidyl-tryptophan modification	DPY19L2 DPY19L2P2	1.64e-04	6	69	2	GO:0018211
GeneOntologyBiologicalProcess	protein C-linked glycosylation via tryptophan	DPY19L2 DPY19L2P2	1.64e-04	6	69	2	GO:0018317
GeneOntologyBiologicalProcess	protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan	DPY19L2 DPY19L2P2	1.64e-04	6	69	2	GO:0018406
GeneOntologyBiologicalProcess	protein C-linked glycosylation	DPY19L2 DPY19L2P2	1.64e-04	6	69	2	GO:0018103
GeneOntologyBiologicalProcess	central nervous system projection neuron axonogenesis	MYCBP2 DCX DCLK1	1.66e-04	32	69	3	GO:0021952
HumanPheno	Pancreatic calcification	PRSS1 PRSS2 ENPP1	6.64e-06	9	23	3	HP:0005213
Domain	SAM_MT43_SUVAR420_2	KMT5B KMT5C	1.27e-05	2	67	2	PS51570
Domain	Hist-Lys_N-MTase_Suvar4-20	KMT5B KMT5C	1.27e-05	2	67	2	IPR025790
Domain	Ca/CaM-dep_Ca-dep_prot_Kinase	STK17B CHEK1 DCX DCLK1	1.10e-04	69	67	4	IPR020636
Domain	DCX	DCX DCLK1	1.88e-04	6	67	2	SM00537
Domain	VDCC_a1su_IQ	CACNA1A CACNA1B	2.63e-04	7	67	2	IPR014873
Domain	-	DCX DCLK1	2.63e-04	7	67	2	3.10.20.230
Domain	GPHH	CACNA1A CACNA1B	2.63e-04	7	67	2	PF16905
Domain	DCX	DCX DCLK1	2.63e-04	7	67	2	PF03607
Domain	GPHH_dom	CACNA1A CACNA1B	2.63e-04	7	67	2	IPR031649
Domain	Ca_chan_IQ	CACNA1A CACNA1B	2.63e-04	7	67	2	SM01062
Domain	Ca_chan_IQ	CACNA1A CACNA1B	2.63e-04	7	67	2	PF08763
Domain	DC	DCX DCLK1	3.50e-04	8	67	2	PS50309
Domain	Doublecortin_dom	DCX DCLK1	3.50e-04	8	67	2	IPR003533
Domain	VDCCAlpha1	CACNA1A CACNA1B	5.60e-04	10	67	2	IPR002077
Domain	Filamin	FLNC MYCBP2	6.83e-04	11	67	2	PF00630
Domain	FILAMIN_REPEAT	FLNC MYCBP2	6.83e-04	11	67	2	PS50194
Domain	Filamin/ABP280_rpt	FLNC MYCBP2	6.83e-04	11	67	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNC MYCBP2	6.83e-04	11	67	2	IPR017868
Domain	Ion_trans_dom	CACNA1A CACNA1B SCN7A RYR2	7.50e-04	114	67	4	IPR005821
Domain	Ion_trans	CACNA1A CACNA1B SCN7A RYR2	7.50e-04	114	67	4	PF00520
Domain	Channel_four-helix_dom	CACNA1A CACNA1B SCN7A	1.12e-03	57	67	3	IPR027359
Domain	-	CACNA1A CACNA1B SCN7A	1.12e-03	57	67	3	1.20.120.350
Domain	-	NAPEPLD DCLRE1A	2.31e-03	20	67	2	3.60.15.10
Domain	Metallo-B-lactamas	NAPEPLD DCLRE1A	2.31e-03	20	67	2	IPR001279
Domain	EGF_CA	THBD THBS2 TLL1	3.65e-03	86	67	3	PF07645
Domain	SET	KMT5B KMT5C	9.50e-03	41	67	2	PF00856
Domain	EGF_CA	THBD THBS2 TLL1	9.61e-03	122	67	3	SM00179
Domain	EGF-like_Ca-bd_dom	THBD THBS2 TLL1	1.00e-02	124	67	3	IPR001881
Domain	EGF	THBD THBS2 TLL1	1.05e-02	126	67	3	PF00008
Pathway	KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY	CACNA1A CACNA1B RYR2	7.21e-06	11	51	3	M47958
Pubmed	Gene conversion-like missense mutations in the human cationic trypsinogen gene and insights into the molecular evolution of the human trypsinogen family.	PRSS3P2 PRSS1 PRSS2	7.47e-09	3	69	3	11073713
Pubmed	The origin of trypsin: evidence for multiple gene duplications in trypsins.	PRSS3P2 PRSS1 PRSS2	7.47e-09	3	69	3	9732462
Pubmed	Doublecortin and doublecortin-like are expressed in overlapping and non-overlapping neuronal cell population: implications for neurogenesis.	DCX DCLK1	3.88e-06	2	69	2	22605579
Pubmed	Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels.	CACNA1A CACNA1B	3.88e-06	2	69	2	23426690
Pubmed	Gene conversion between cationic trypsinogen (PRSS1) and the pseudogene trypsinogen 6 (PRSS3P2) in patients with chronic pancreatitis.	PRSS3P2 PRSS1	3.88e-06	2	69	2	25546417
Pubmed	Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination.	KMT5B KMT5C	3.88e-06	2	69	2	17846168
Pubmed	The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity.	KMT5B KMT5C	3.88e-06	2	69	2	28114273
Pubmed	Preferential dimethylation of histone H4 lysine 20 by Suv4-20.	KMT5B KMT5C	3.88e-06	2	69	2	18296440
Pubmed	Both doublecortin and doublecortin-like kinase play a role in cortical interneuron migration.	DCX DCLK1	3.88e-06	2	69	2	17409252
Pubmed	Molecular pathology and evolutionary and physiological implications of pancreatitis-associated cationic trypsinogen mutations.	PRSS3P2 PRSS1	3.88e-06	2	69	2	11702203
Pubmed	Suv4-20h abrogation enhances telomere elongation during reprogramming and confers a higher tumorigenic potential to iPS cells.	KMT5B KMT5C	3.88e-06	2	69	2	22022429
Pubmed	Enhancement of cytotoxic effects of gemcitabine by Dclk1 inhibition through suppression of Chk1 phosphorylation in human pancreatic cancer cells.	CHEK1 DCLK1	3.88e-06	2	69	2	29048622
Pubmed	Comparative analyses of SUV420H1 isoforms and SUV420H2 reveal differences in their cellular localization and effects on myogenic differentiation.	KMT5B KMT5C	3.88e-06	2	69	2	21206904
Pubmed	Alcohol Consumption and Cigarette Smoking are Important Modifiers of the Association Between Acute Pancreatitis and the PRSS1-PRSS2 Locus in Men.	PRSS1 PRSS2	3.88e-06	2	69	2	27846138
Pubmed	Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2.	KMT5B KMT5C	3.88e-06	2	69	2	24396869
Pubmed	Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2).	PRSS1 PRSS2	3.88e-06	2	69	2	14695529
Pubmed	Mouse oocyte meiosis is disturbed by knockdown of Suv4-20h.	KMT5B KMT5C	3.88e-06	2	69	2	22951141
Pubmed	Synthetic Aβ oligomers (Aβ(1-42) globulomer) modulate presynaptic calcium currents: prevention of Aβ-induced synaptic deficits by calcium channel blockers.	CACNA1A CACNA1B	3.88e-06	2	69	2	23376566
Pubmed	Gene conversion between functional trypsinogen genes PRSS1 and PRSS2 associated with chronic pancreatitis in a six-year-old girl.	PRSS1 PRSS2	3.88e-06	2	69	2	15776435
Pubmed	KIAA0369, doublecortin-like kinase, is expressed during brain development.	DCX DCLK1	3.88e-06	2	69	2	10533048
Pubmed	Absence of Dpy19l2, a new inner nuclear membrane protein, causes globozoospermia in mice by preventing the anchoring of the acrosome to the nucleus.	DPY19L2 DPY19L2P2	3.88e-06	2	69	2	22764053
Pubmed	The DCX-domain tandems of doublecortin and doublecortin-like kinase.	DCX DCLK1	3.88e-06	2	69	2	12692530
Pubmed	Pancreatitis-Associated PRSS1-PRSS2 Haplotype Alters T-Cell Receptor Beta (TRB) Repertoire More Strongly Than PRSS1 Expression.	PRSS1 PRSS2	3.88e-06	2	69	2	36191639
Pubmed	A novel route to product specificity in the Suv4-20 family of histone H4K20 methyltransferases.	KMT5B KMT5C	3.88e-06	2	69	2	24049080
Pubmed	CaV 2.1 α1 subunit motifs that control presynaptic CaV 2.1 subtype abundance are distinct from CaV 2.1 preference.	CACNA1A CACNA1B	3.88e-06	2	69	2	38155373
Pubmed	A new activity of doublecortin in recognition of the phospho-FIGQY tyrosine in the cytoplasmic domain of neurofascin.	NFASC DCX	3.88e-06	2	69	2	12223548
Pubmed	Doublecortin (Dcx) family proteins regulate filamentous actin structure in developing neurons.	DCX DCLK1	3.88e-06	2	69	2	23303949
Pubmed	Hereditary pancreatitis caused by a double gain-of-function trypsinogen mutation.	PRSS1 PRSS2	3.88e-06	2	69	2	18461367
Pubmed	Role of the Common PRSS1-PRSS2 Haplotype in Alcoholic and Non-Alcoholic Chronic Pancreatitis: Meta- and Re-Analyses.	PRSS1 PRSS2	3.88e-06	2	69	2	33202925
Pubmed	Expression of tumor-associated trypsinogens (TAT-1 and TAT-2) in prostate cancer.	PRSS1 PRSS2	3.88e-06	2	69	2	15651064
Pubmed	Histone H4K20 tri-methylation at late-firing origins ensures timely heterochromatin replication.	KMT5B KMT5C	3.88e-06	2	69	2	28778956
Pubmed	The doublecortin and doublecortin-like kinase 1 genes cooperate in murine hippocampal development.	DCX DCLK1	3.88e-06	2	69	2	16766710
Pubmed	Expression analysis of P/Q-type Ca2+ channel alpha 1A subunit mRNA in olfactory mitral cell in N-type Ca2+ channel alpha 1B subunit gene-deficient mice.	CACNA1A CACNA1B	3.88e-06	2	69	2	15050706
Pubmed	Expression and chromosomal localization of KIAA0369, a putative kinase structurally related to Doublecortin.	DCX DCLK1	3.88e-06	2	69	2	9747029
Pubmed	Immunoreactive anionic and cationic trypsin in human serum.	PRSS1 PRSS2	3.88e-06	2	69	2	2598466
Pubmed	SUV4-20 activity in the preimplantation mouse embryo controls timely replication.	KMT5B KMT5C	3.88e-06	2	69	2	27920088
Pubmed	Pre-diagnostic levels of anionic trypsinogen, cationic trypsinogen, and pancreatic secretory trypsin inhibitor in relation to pancreatic cancer risk.	PRSS1 PRSS2	3.88e-06	2	69	2	20484960
Pubmed	Dpy19l2-deficient globozoospermic sperm display altered genome packaging and DNA damage that compromises the initiation of embryo development.	DPY19L2 DPY19L2P2	3.88e-06	2	69	2	25354700
Pubmed	Subcellular localization of phospholipase Cζ in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation.	DPY19L2 DPY19L2P2	3.88e-06	2	69	2	25354701
Pubmed	Trypsinogen (PRSS1 and PRSS2) gene dosage correlates with pancreatitis risk across genetic and transgenic studies: a systematic review and re-analysis.	PRSS1 PRSS2	3.88e-06	2	69	2	35089416
Pubmed	Trypsinogen copy number mutations in patients with idiopathic chronic pancreatitis.	PRSS1 PRSS2	3.88e-06	2	69	2	18063422
Pubmed	Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma.	PRSS1 PRSS2	1.16e-05	3	69	2	24146905
Pubmed	Doublecortin-like, a microtubule-associated protein expressed in radial glia, is crucial for neuronal precursor division and radial process stability.	DCX DCLK1	1.16e-05	3	69	2	17313568
Pubmed	Dynamics of Sun5 localization during spermatogenesis in wild type and Dpy19l2 knock-out mice indicates that Sun5 is not involved in acrosome attachment to the nuclear envelope.	DPY19L2 DPY19L2P2	1.16e-05	3	69	2	25775128
Pubmed	The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2.	DCX DCLK1	1.16e-05	3	69	2	23918955
Pubmed	FSHD muscular dystrophy region gene 1 binds Suv4-20h1 histone methyltransferase and impairs myogenesis.	KMT5B KMT5C	1.16e-05	3	69	2	23720823
Pubmed	Munc13-3 Is Required for the Developmental Localization of Ca2+ Channels to Active Zones and the Nanopositioning of Cav2.1 Near Release Sensors.	CACNA1A CACNA1B	1.16e-05	3	69	2	29466725
Pubmed	Trypsin-mediated enzymatic degradation of type II collagen in the human vitreous.	PRSS1 PRSS2	1.16e-05	3	69	2	23882137
Pubmed	Doublecortin (DCX) and doublecortin-like (DCL) are differentially expressed in the early but not late stages of murine neocortical development.	DCX DCLK1	1.16e-05	3	69	2	18231966
Pubmed	Ankyrin-B regulates Cav2.1 and Cav2.2 channel expression and targeting.	CACNA1A CACNA1B	1.16e-05	3	69	2	24394417
Pubmed	Altered mucosal DNA methylation in parallel with highly active Helicobacter pylori-related gastritis.	FLNC THBD	1.16e-05	3	69	2	23292007
Pubmed	Molecular basis for specific regulation of neuronal kinesin-3 motors by doublecortin family proteins.	DCX DCLK1	1.16e-05	3	69	2	22857951
Pubmed	The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.	CACNA1A CACNA1B	1.16e-05	3	69	2	38996073
Pubmed	Duplication and relocation of the functional DPY19L2 gene within low copy repeats.	DPY19L2 DPY19L2P2	1.16e-05	3	69	2	16526957
Pubmed	The Suv420h histone methyltransferases regulate PPAR-γ and energy expenditure in response to environmental stimuli.	KMT5B KMT5C	1.16e-05	3	69	2	31001581
Pubmed	Association of claudin2 and PRSS1-PRSS2 polymorphisms with idiopathic recurrent acute and chronic pancreatitis: A case-control study from India.	PRSS1 PRSS2	1.16e-05	3	69	2	26110235
Pubmed	Divergent roles of SPINK1 and PRSS2 variants in tropical calcific pancreatitis.	PRSS1 PRSS2	1.16e-05	3	69	2	19077465
Pubmed	CD4-binding regions of human immunodeficiency virus envelope glycoprotein gp120 defined by proteolytic digestion.	PRSS1 PRSS2	1.16e-05	3	69	2	1763044
Pubmed	Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics.	CACNA1A CACNA1B	1.16e-05	3	69	2	24523520
Pubmed	Molecular moieties masking Ca2+-dependent facilitation of voltage-gated Cav2.2 Ca2+ channels.	CACNA1A CACNA1B	1.16e-05	3	69	2	29208674
Pubmed	Alternative transcripts of Dclk1 and Dclk2 and their expression in doublecortin knockout mice.	DCX DCLK1	1.16e-05	3	69	2	18075264
Pubmed	Molecular Basis of Regulating High Voltage-Activated Calcium Channels by S-Nitrosylation.	CACNA1A CACNA1B	1.16e-05	3	69	2	26507659
Pubmed	Off-target effect of doublecortin family shRNA on neuronal migration associated with endogenous microRNA dysregulation.	DCX DCLK1	1.16e-05	3	69	2	24945770
Pubmed	The retinoblastoma protein regulates pericentric heterochromatin.	KMT5B KMT5C	1.16e-05	3	69	2	16612004
Pubmed	Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry.	CACNA1A CACNA1B	2.32e-05	4	69	2	32616470
Pubmed	Constitutive and ghrelin-dependent GHSR1a activation impairs CaV2.1 and CaV2.2 currents in hypothalamic neurons.	CACNA1A CACNA1B	2.32e-05	4	69	2	26283199
Pubmed	Variants in doublecortin- and calmodulin kinase like 1, a gene up-regulated by BDNF, are associated with memory and general cognitive abilities.	DCX DCLK1	2.32e-05	4	69	2	19844571
Pubmed	Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis.	PRSS1 PRSS2	2.32e-05	4	69	2	33515547
Pubmed	A protein phosphatase 2calpha-Ca2+ channel complex for dephosphorylation of neuronal Ca2+ channels phosphorylated by protein kinase C.	CACNA1A CACNA1B	2.32e-05	4	69	2	15728831
Pubmed	Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study.	PRSS1 PRSS2	2.32e-05	4	69	2	25253127
Pubmed	The MAP1B-LC1/UBE2L3 complex catalyzes degradation of cell surface CaV2.2 channels.	CACNA1A CACNA1B	2.32e-05	4	69	2	25483588
Pubmed	Cerebellar granule cell signaling is indispensable for normal motor performance.	CACNA1A CACNA1B	2.32e-05	4	69	2	37141091
Pubmed	The X-linked intellectual disability gene product and E3 ubiquitin ligase KLHL15 degrades doublecortin proteins to constrain neuronal dendritogenesis.	DCX DCLK1	2.32e-05	4	69	2	33199366
Pubmed	Interactions of Rabconnectin-3 with Cav2 calcium channels.	CACNA1A CACNA1B	2.32e-05	4	69	2	31253182
Pubmed	Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins.	KMT5B KMT5C	2.32e-05	4	69	2	16322686
Pubmed	PR-SET7 and SUV4-20H regulate H4 lysine-20 methylation at imprinting control regions in the mouse.	KMT5B KMT5C	2.32e-05	4	69	2	18724273
Pubmed	Cloning, characterization and nucleotide sequences of two cDNAs encoding human pancreatic trypsinogens.	PRSS1 PRSS2	2.32e-05	4	69	2	3011602
Pubmed	G protein-gated inhibitory module of N-type (ca(v)2.2) ca2+ channels.	CACNA1A CACNA1B	2.32e-05	4	69	2	15953418
Pubmed	Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk.	PRSS1 PRSS2 CHEK1	3.23e-05	31	69	3	19690177
Pubmed	Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.	CACNA1A CACNA1B	3.86e-05	5	69	2	8825650
Pubmed	FAM209 associates with DPY19L2, and is required for sperm acrosome biogenesis and fertility in mice.	DPY19L2 DPY19L2P2	3.86e-05	5	69	2	34471926
Pubmed	PRSS1-Related Hereditary Pancreatitis	PRSS1 PRSS2	3.86e-05	5	69	2	22379635
Pubmed	Identification of a cardiac isoform of the murine calcium channel alpha1C (Cav1.2-a) subunit and its preferential binding with the beta2 subunit.	CACNA1A CACNA1B	3.86e-05	5	69	2	16787652
Pubmed	Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.	CACNA1A CACNA1B	3.86e-05	5	69	2	15451373
Pubmed	Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.	CACNA1A CACNA1B	3.86e-05	5	69	2	11296258
Pubmed	A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin.	KMT5B KMT5C	5.79e-05	6	69	2	15145825
Pubmed	DCAMKL1 encodes a protein kinase with homology to doublecortin that regulates microtubule polymerization.	DCX DCLK1	5.79e-05	6	69	2	11124993
Pubmed	Autoactivation of mouse trypsinogens is regulated by chymotrypsin C via cleavage of the autolysis loop.	PRSS1 PRSS2	5.79e-05	6	69	2	23814066
Pubmed	An action potential initiation mechanism in distal axons for the control of dopamine release.	CACNA1A CACNA1B	5.79e-05	6	69	2	35324301
Pubmed	A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse.	KMT5B KMT5C	5.79e-05	6	69	2	18676810
Pubmed	Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.	CACNA1A CACNA1B	5.79e-05	6	69	2	12827191
Pubmed	Urinary matrix metalloproteinase -8, -9, -14 and their regulators (TRY-1, TRY-2, TATI) in patients with diabetic nephropathy.	PRSS1 PRSS2	5.79e-05	6	69	2	18428024
Pubmed	Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors.	CACNA1A CACNA1B	5.79e-05	6	69	2	9238069
Pubmed	Yeast two-hybrid screening for proteins that interact with alpha1-adrenergic receptors.	FLNC ADRA1D	5.79e-05	6	69	2	15525470
Pubmed	beta subunit reshuffling modifies N- and P/Q-type Ca2+ channel subunit compositions in lethargic mouse brain.	CACNA1A CACNA1B	5.79e-05	6	69	2	10328888
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	CACNA1A CACNA1B RYR2	6.00e-05	38	69	3	30786075
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	MYCBP2 UFD1 IQCB1 USP24 STRIP2	6.57e-05	212	69	5	33853758
Pubmed	Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.	PRSS1 PRSS2	8.09e-05	7	69	2	23143602
Pubmed	Rebuilding essential active zone functions within a synapse.	CACNA1A CACNA1B	8.09e-05	7	69	2	35176221
Pubmed	The p97-UFD1L-NPL4 protein complex mediates cytokine-induced IκBα proteolysis.	NFKBIA UFD1	8.09e-05	7	69	2	24248593
Cytoband	7q34	PRSS3P2 PRSS1 PRSS2	2.08e-03	167	69	3	7q34
Cytoband	15q14	MGA DPH6	2.50e-03	49	69	2	15q14
Cytoband	1q43	BECN2 RYR2	2.71e-03	51	69	2	1q43
GeneFamily	Doublecortin superfamily	DCX DCLK1	2.34e-04	10	42	2	1369
GeneFamily	Calcium voltage-gated channel subunits	CACNA1A CACNA1B	1.65e-03	26	42	2	253
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT5B KMT5C	2.82e-03	34	42	2	487
Coexpression	GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_24H_INCUBATION_UP	RSBN1 BMP5 IGF2R ZNF329 DMBT1 PADI2	1.31e-05	199	68	6	M6577
Coexpression	BUCKANOVICH_T_LYMPHOCYTE_HOMING_ON_TUMOR_UP	DPY19L2 MYCBP2 NME9	2.15e-05	21	68	3	M17086
Coexpression	BENPORATH_ES_WITH_H3K27ME3	CACNA1A CACNA1B THBD THBS2 DPY19L2 AZIN2 TLL1 SIDT1 DPY19L2P2 PADI2 DCX DCLK1	2.66e-05	1115	68	12	M10371
Coexpression	NABA_MATRISOME_HYPERPLASTIC_PANCREATIC_ISLETS	PRSS1 PRSS2 DMBT1	4.16e-05	26	68	3	MM17051
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBGABA	CACNA1A CACNA1B MYCBP2 NECTIN1 SCN7A NFASC DCX DCLK1 RYR2	8.19e-05	703	68	9	M39070
Coexpression	JEPSEN_SMRT_TARGETS	IGF2R MGA DCX	8.62e-05	33	68	3	MM745
Coexpression	JEPSEN_SMRT_TARGETS	IGF2R MGA DCX	8.62e-05	33	68	3	M1773
Coexpression	GSE14699_NAIVE_VS_ACT_CD8_TCELL_DN	TDRKH USP24 SIDT1 METTL8 MGA	9.29e-05	175	68	5	M2940
Coexpression	GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_DN	CACNA1A IGF2R MYCBP2 TMEM245 NFASC	9.80e-05	177	68	5	M7632
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	BMP5 THBS2 PDLIM7 SCN7A NFASC DCLK1 RYR2	1.93e-08	194	68	7	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	BMP5 SCN7A PEAK1 DCLK1 RYR2 FAM110B	4.61e-07	190	68	6	7986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	BMP5 THBS2 SCN7A NFASC DCLK1 RYR2	4.61e-07	190	68	6	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BMP5 THBS2 SCN7A NFASC DCLK1 RYR2	5.54e-07	196	68	6	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	BMP5 THBS2 SCN7A NFASC DCLK1 RYR2	5.87e-07	198	68	6	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BMP5 THBS2 SCN7A NFASC DCLK1 RYR2	5.87e-07	198	68	6	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	Fibroblasts\|World / lung cells shred on cell class, cell subclass, sample id	BMP5 FLNC THBS2 SCN7A NFASC RYR2	6.05e-07	199	68	6	e2b6752fcabd5249a166486ae6796f2c97c1fcaf
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BMP5 THBS2 SCN7A NFASC DCLK1 RYR2	6.23e-07	200	68	6	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	Basal_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	CRYBG2 PTPN14 ZNF329 NECTIN1 DCLRE1A	4.37e-06	158	68	5	dd069a822e9698e6dddc155d9a5b52383f7879d5
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AMBP PRSS1 PRSS2 NECTIN1 CTSE	6.07e-06	169	68	5	a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 DUSP29 SCN7A NFASC DCLK1	6.42e-06	171	68	5	5d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	PRSS1 PRSS2 FLNC CRYBG2 CTSE	6.61e-06	172	68	5	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FLNC PDLIM7 ENPP1 BHMT2 RYR2	7.81e-06	178	68	5	8ec2a25dda96c9cc9c2904b6cb18f75a293f4969
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FLNC PDLIM7 ENPP1 BHMT2 RYR2	7.81e-06	178	68	5	6c91331196696e0cf239d105f458e3230659fa38
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	BMP5 FLNC THBD THBS2 ENPP1	7.81e-06	178	68	5	cda7695411655bd6d0ba69e5041ca7530a9dad3a
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	CACNA1B TDRKH THBD NECTIN1 DCLK1	8.02e-06	179	68	5	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLNC THBD AZIN2 TLL1 BHMT2	8.93e-06	183	68	5	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BMP5 THBS2 ADRA1D NFASC DCLK1	9.17e-06	184	68	5	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	BMP5 SCN7A DCLK1 RYR2 FAM110B	9.66e-06	186	68	5	7def03dd856b765bd3f493288641981c4f7fd26e
ToppCell	IPF-Epithelial-Aberrant_Basaloid\|Epithelial / Disease state, Lineage and Cell class	PRSS1 PRSS2 PDLIM7 CTSE DCLK1	1.04e-05	189	68	5	4178be3292ff4a8a1d8098f638d4b8d15164d2c6
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 PDLIM7 NFASC DCLK1 RYR2	1.07e-05	190	68	5	2e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 PDLIM7 NFASC DCLK1 RYR2	1.07e-05	190	68	5	0028f886c789ba238c031eae5d96acaed4af8c25
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THBS2 ADRA1D SCN7A DCX DCLK1	1.15e-05	193	68	5	549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	BMP5 THBS2 SCN7A NFASC RYR2	1.15e-05	193	68	5	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	AMBP BMP5 FLNC ENPP1 SCN7A	1.15e-05	193	68	5	e5016959f24370579a8770787e96869f264cf7b3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 PDLIM7 NFASC DCLK1 RYR2	1.24e-05	196	68	5	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	IPF-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	BMP5 THBS2 SCN7A DCLK1 RYR2	1.24e-05	196	68	5	7fc9894ceb79dab9f0495acc84e2d6d0d1c69bb7
ToppCell	IPF-Stromal-Myofibroblast\|IPF / Disease state, Lineage and Cell class	BMP5 THBS2 SCN7A DCLK1 RYR2	1.24e-05	196	68	5	2d0a48e49b3b37bb66e33e74c52915911e1f8a74
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 PDLIM7 NFASC DCLK1 RYR2	1.24e-05	196	68	5	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDLIM7 ENPP1 BHMT2 NFASC RYR2	1.24e-05	196	68	5	9830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	BMP5 THBS2 SCN7A DCLK1 RYR2	1.27e-05	197	68	5	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	BMP5 THBS2 SCN7A DCLK1 RYR2	1.27e-05	197	68	5	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	IPF-Stromal\|IPF / Disease state, Lineage and Cell class	BMP5 THBS2 SCN7A DCLK1 RYR2	1.31e-05	198	68	5	ece914c32c9b123b779aa9624b92e6230763a20e
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNC DUSP29 PDLIM7 NFASC RYR2	1.31e-05	198	68	5	22e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BMP5 THBS2 SCN7A DCLK1 RYR2	1.31e-05	198	68	5	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	BMP5 THBS2 SCN7A DCLK1 RYR2	1.34e-05	199	68	5	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	CACNA1A CACNA1B MYCBP2 DCLK1 RYR2	1.37e-05	200	68	5	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BMP5 THBS2 SCN7A NFASC RYR2	1.37e-05	200	68	5	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BMP5 THBS2 SCN7A DCLK1 RYR2	1.37e-05	200	68	5	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	Tracheal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BMP5 THBS2 ENPP1 SCN7A DCLK1	1.37e-05	200	68	5	c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BMP5 THBS2 SCN7A NFASC RYR2	1.37e-05	200	68	5	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	cellseq2-Mesenchymal-Fibroblastic\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BMP5 THBS2 SCN7A BHMT2 DCLK1	1.37e-05	200	68	5	1c10597edd532bf172ca09870a937d35e2585081
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS1 PRSS2 DMBT1 PADI2	2.11e-05	106	68	4	3aa55c3db4e4abd39c8f2f89f2516927d94ad9d7
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-\|Striatum / BrainAtlas - Mouse McCarroll V32	BMP5 FLNC THBD THBS2	5.28e-05	134	68	4	a3547a68012d879d4dfe80394eace70808722e43
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)\|Striatum / BrainAtlas - Mouse McCarroll V32	BMP5 FLNC THBD THBS2	5.28e-05	134	68	4	9458e2d0dbc18d9025b66b59f3ecc2fbc5384940
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLNC IGF2R ADGRF1 PADI2	6.62e-05	142	68	4	191a13bba143ecdfc2bfd797c3ac191481388298
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FLNC IGF2R ADGRF1 PADI2	6.80e-05	143	68	4	b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	BMP5 FLNC THBS2 ENPP1	8.84e-05	153	68	4	e9c6fb5c41adb6595c66c3a917fe455348279e54
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	BMP5 FLNC THBS2 ENPP1	8.84e-05	153	68	4	b8b5ff7d2feea3e3a352fb5530e49f639fe1ff88
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP\|Thalamus / BrainAtlas - Mouse McCarroll V32	BMP5 FLNC THBS2 ENPP1	8.84e-05	153	68	4	2513edfae62a44e51d3556675a096723194c966c
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-Treg\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRSS1 MANBA STK17B METTL8	9.77e-05	157	68	4	2c767c526abcc8adea6ec4eb2cc333060bb213b5
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRSS2 DPY19L2 ADGRF1 EXOSC7	9.77e-05	157	68	4	c17c5c01fcb65c453690c265ec4f300ecdfefd34
ToppCell	COPD-Epithelial-Aberrant_Basaloid\|Epithelial / Disease state, Lineage and Cell class	PRSS1 PRSS2 PDLIM7 DCLK1	1.00e-04	158	68	4	8f66979e92f886d86cecbd26aaa0c5915c049734
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUSP29 STK17B ADGRF1 CTSE	1.05e-04	160	68	4	97c899df1b57fd2bd1867e02bfedf1920c00ad17
ToppCell	356C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	BMP5 SCN7A PEAK1 RYR2	1.05e-04	160	68	4	0293b244c063a62819690bf22bbc2681f8d15252
ToppCell	356C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	BMP5 SCN7A PEAK1 RYR2	1.05e-04	160	68	4	3eaae86fa08f7651021316f8e5811bf48055591e
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D122\|Adult / Lineage, Cell type, age group and donor	DUSP29 PDLIM7 NFASC RYR2	1.08e-04	161	68	4	64891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS1 PRSS2 ENPP1 DMBT1	1.18e-04	165	68	4	622aca1d49bd8c917b131e4f4959d9dba411d22b
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1B NAPEPLD NME9 RYR2	1.18e-04	165	68	4	6d315e0734079ad05336cc2c3f24d870c9105bc8
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1B NAPEPLD NME9 RYR2	1.18e-04	165	68	4	84f5597b1bb75f42de9a224196bb8ac198bbe3bf
ToppCell	356C-Fibroblasts-Fibroblast-D\|356C / Donor, Lineage, Cell class and subclass (all cells)	THBS2 SCN7A BHMT2 RYR2	1.21e-04	166	68	4	7286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell	Basal_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	PRSS1 PRSS2 PTPN14 NECTIN1	1.21e-04	166	68	4	23c04d1fba0c1733ccd0e4378fae2edde4fd0a7b
ToppCell	356C-Fibroblasts-Fibroblast-D-\|356C / Donor, Lineage, Cell class and subclass (all cells)	THBS2 SCN7A BHMT2 RYR2	1.21e-04	166	68	4	7c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP\|Hippocampus / BrainAtlas - Mouse McCarroll V32	BMP5 FLNC THBS2 ENPP1	1.27e-04	168	68	4	26aa96b2b547d11941cb803995ea3d302ee0518c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 DUSP29 SCN7A DCLK1	1.27e-04	168	68	4	4b2d29a7843bf45922038c093ca7ec0600756adc
ToppCell	metastatic_Brain-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	AZIN2 KMT5C NECTIN1 SIDT1	1.27e-04	168	68	4	4bf3f85aac4b335efa93d22c9ce7b153cb5ce152
ToppCell	Endothelial-B-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	FLNC PTPN14 TLL1 BHMT2	1.27e-04	168	68	4	4977c3837fbb1f36c89fddd5764e37290ac25ad8
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	BMP5 PDLIM7 NFASC DCLK1	1.33e-04	170	68	4	fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	BMP5 PDLIM7 NFASC DCLK1	1.33e-04	170	68	4	03044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADRA1D NFASC RYR2 FAM110B	1.33e-04	170	68	4	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	METTL8 CHEK1 CTSE STRIP2	1.39e-04	172	68	4	e9b97f37bb1732ad9aa89c5e9b513d14022801ac
ToppCell	Endothelial-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	THBD PTPN14 NFASC DCLK1	1.39e-04	172	68	4	d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS1 PRSS2 DMBT1 PADI2	1.42e-04	173	68	4	c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCell	3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNC DPY19L2 AZIN2 BHMT2	1.42e-04	173	68	4	85083b9ce20351dd69aa2327ad087b848b4307ff
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	PDLIM7 ENPP1 NFASC RYR2	1.42e-04	173	68	4	a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS1 PRSS2 DMBT1 PADI2	1.42e-04	173	68	4	f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AMBP CACNA1A ADGRF1 DCX	1.42e-04	173	68	4	f31e738c2b3b319fb40b0b16b2393a51c9a8999c
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS1 PRSS2 DMBT1 PADI2	1.45e-04	174	68	4	165e14cad57e90aa247dcecfaa3c2e8ff2a470ad
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS1 PRSS2 DMBT1 PADI2	1.45e-04	174	68	4	4289dfc7613db4bb3d706b9b65d06e84c0c53558
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 ADRA1D NFASC DCLK1	1.48e-04	175	68	4	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PTPN14 TRNAU1AP MARF1 DCLRE1A	1.48e-04	175	68	4	69ed3c7c45df6bef70f5f2ff003531160bf3b32b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPY19L2 ADGRF1 EXOSC7 FAM110B	1.52e-04	176	68	4	25ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBD SCN7A CHEK1 STRIP2	1.52e-04	176	68	4	269326c2bf44a9003d95bc6dbc839f08f25737ca
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	THBS2 SCN7A BHMT2 DCLK1	1.52e-04	176	68	4	2e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell	AT1-AT2_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	PRSS1 PRSS2 CTSE DCLK1	1.52e-04	176	68	4	f86832cfeff5b3cfffe4455c1b96a1420d48ba1e
ToppCell	COPD-Epithelial-Aberrant_Basaloid\|COPD / Disease state, Lineage and Cell class	PRSS1 PRSS2 CTSE DCLK1	1.52e-04	176	68	4	11d867bcb4f2471b4e13a5f7dc1c24286197f26d
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	THBS2 SCN7A BHMT2 DCLK1	1.52e-04	176	68	4	f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BMP5 ENPP1 DCLK1 RYR2	1.55e-04	177	68	4	9ec7f1e64312d26d434b3312b58386715dbad644
ToppCell	COPD-Epithelial-Aberrant_Basaloid\|World / Disease state, Lineage and Cell class	PRSS1 PRSS2 CTSE DCLK1	1.55e-04	177	68	4	22b7cda748cf5e665be54ca5bae89f0c130d5e7f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BMP5 ENPP1 DCLK1 RYR2	1.55e-04	177	68	4	016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 STK17B SIDT1 CTSE	1.58e-04	178	68	4	a9a8567d8fdc0fffd612fee16b5b29ef7b1c9307
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRSS2 DMBT1 CTSE DCLK1	1.58e-04	178	68	4	f3b5eeca6081d65d48824b5d13e3b8eb5fdeb2dd
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNC PTPN14 BHMT2 PEAK1	1.58e-04	178	68	4	ad3de3e03a401dac64431a541899445262246347
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 STK17B SIDT1 CTSE	1.58e-04	178	68	4	5ecbea15efd304057aef826ec2f385997bfaf0c9
ToppCell	droplet-Bladder-nan-24m-Epithelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TDRKH ADRA1D SCN7A	1.62e-04	179	68	4	3d6bb3cfe89d60f2f00aead9341f9967e5313763
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS1 PRSS2 DMBT1	1.68e-04	70	68	3	26178ee967d647224d93c7a6380f2d15d8fcfb8f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1A STK17B NFASC PEAK1	1.69e-04	181	68	4	a2058d658f07ab6f0a28d2622f3090b4cde6f763
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PDLIM7 TLL1 DCX FAM110B	1.69e-04	181	68	4	7e3bcfa2ba5b98a7df5854aa6e7a31e9a71faa8a
ToppCell	COVID-19-Heart-Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BMP5 ENPP1 SCN7A NFASC	1.69e-04	181	68	4	33cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-5\|TCGA-Colorectal / Sample_Type by Project: Shred V9	SIDT1 ANO7 ADGRF1 CTSE	1.69e-04	181	68	4	8fcc9e77fee7c248df26b6c59b10e672242e2084
Computational	Neighborhood of SERPINI2	PRSS3P2 PRSS1 PRSS2	1.68e-04	25	47	3	GNF2_SERPINI2
Computational	Neighborhood of SPINK1	PRSS3P2 PRSS1 PRSS2	2.13e-04	27	47	3	GNF2_SPINK1
Drug	verbascose	PRSS1 PRSS2 MANBA	4.32e-06	11	69	3	CID000441434
Drug	leys	CACNA1A CACNA1B ENPP1	4.32e-06	11	69	3	CID000484683
Drug	polybrene	PRSS1 PRSS2 THBD ENPP1	2.70e-05	57	69	4	CID000024769
Drug	N-allylglycine	PRSS1 PRSS2	2.71e-05	3	69	2	CID000076651
Drug	N-acetyl-L-norvaline methyl ester	PRSS1 PRSS2	2.71e-05	3	69	2	CID000150916
Drug	YAKR-CK	PRSS1 PRSS2	2.71e-05	3	69	2	CID005487256
Drug	schizopeptin 791	PRSS1 PRSS2	2.71e-05	3	69	2	CID000636821
Drug	2 alpha-bromoacetoxyprogesterone	PRSS1 PRSS2	2.71e-05	3	69	2	CID000135256
Drug	Lapg-nh2	PRSS1 PRSS2	2.71e-05	3	69	2	CID003082486
Drug	Methotrexate-polylysine	PRSS1 PRSS2	2.71e-05	3	69	2	CID000163214
Drug	methyl octanesulfonate	PRSS1 PRSS2	2.71e-05	3	69	2	CID000165858
Drug	3HFGB	PRSS1 PRSS2	2.71e-05	3	69	2	CID000126268
Drug	4-chlorobenzenediazonium hexafluorophosphate	PRSS1 PRSS2	2.71e-05	3	69	2	CID002723983
Drug	methyl lignocerate	PRSS1 PRSS2	2.71e-05	3	69	2	CID000075546
Drug	10-(carboxyethyl)flavin	PRSS1 PRSS2	2.71e-05	3	69	2	CID003082170
Drug	Z-Lys-CH2Cl	PRSS1 PRSS2	2.71e-05	3	69	2	CID000127335
Drug	2,6-dimethyl-3-pyridinol	PRSS1 PRSS2	2.71e-05	3	69	2	CID000070732
Drug	N-phosphopyridoxyl-L-serine	PRSS1 PRSS2	2.71e-05	3	69	2	CID000195946
Drug	Z-Arg-OH	PRSS1 PRSS2	2.71e-05	3	69	2	CID000071055
Drug	GB-107	PRSS1 PRSS2	2.71e-05	3	69	2	CID000056813
Drug	p-amidinophenylpyruvate	PRSS1 PRSS2	2.71e-05	3	69	2	CID000444106
Drug	v 1194	PRSS1 PRSS2	2.71e-05	3	69	2	CID000074702
Drug	mitorubrinic acid	PRSS1 PRSS2	2.71e-05	3	69	2	CID000379537
Drug	ASA-PE	PRSS1 PRSS2	2.71e-05	3	69	2	CID003037809
Drug	L-TAPA	PRSS1 PRSS2	2.71e-05	3	69	2	CID000193734
Drug	0ZI	PRSS1 PRSS2 THBD	2.93e-05	20	69	3	CID000122235
Drug	Bvpam	CACNA1A PRSS1 PRSS2	3.41e-05	21	69	3	CID000125185
Drug	IAA-94	CACNA1A CACNA1B ENPP1 RYR2	3.54e-05	61	69	4	CID000003667
Drug	AC 110	CACNA1A CACNA1B	5.41e-05	4	69	2	CID000022860
Drug	AC1LAOUV	PRSS1 PRSS2	5.41e-05	4	69	2	CID000492408
Drug	5'-S-propynyl-5'-thioadenosine	PRSS1 PRSS2	5.41e-05	4	69	2	CID000492409
Drug	4-Amino-3-nitrobenzoic acid	PRSS1 PRSS2	5.41e-05	4	69	2	CID000074115
Drug	4-ethylpiperidine	PRSS1 PRSS2	5.41e-05	4	69	2	CID000076704
Drug	torquatone	PRSS1 PRSS2	5.41e-05	4	69	2	CID000256516
Drug	AC1Q5JO7	PRSS1 PRSS2	5.41e-05	4	69	2	CID000128324
Drug	Dsdgk	PRSS1 PRSS2	5.41e-05	4	69	2	CID000130454
Drug	mGBSOM	PRSS1 PRSS2	5.41e-05	4	69	2	CID003080804
Drug	Ba-O	PRSS1 PRSS2	5.41e-05	4	69	2	CID000002280
Drug	SQ 27,239	AMBP NFKBIA	5.41e-05	4	69	2	CID000055320
Drug	NSC-45351	PRSS1 PRSS2	5.41e-05	4	69	2	CID000018046
Drug	indomethacin-NHS	PRSS1 PRSS2	5.41e-05	4	69	2	CID000128571
Drug	bromomesaconic acid	PRSS1 PRSS2	5.41e-05	4	69	2	CID006449799
Drug	N-carbobenzoxyglycine vinyl ester	PRSS1 PRSS2	5.41e-05	4	69	2	CID000047309
Drug	NSC-13568	PRSS1 PRSS2	5.41e-05	4	69	2	CID000224783
Drug	xylaric acid	PRSS1 PRSS2	5.41e-05	4	69	2	CID003084064
Drug	3-FLUOROSIALIC ACID	IGF2R ENPP1 IQCB1	6.59e-05	26	69	3	CID005288256
Drug	Sr 42128	PRSS1 PRSS2	9.00e-05	5	69	2	CID005487043
Drug	S 8510	CACNA1A CACNA1B	9.00e-05	5	69	2	CID005488383
Drug	4-TGPAP	PRSS1 PRSS2	9.00e-05	5	69	2	CID000132086
Drug	PTA-Arg	PRSS1 PRSS2	9.00e-05	5	69	2	CID000194378
Drug	I 333	PRSS1 PRSS2	9.00e-05	5	69	2	CID000533915
Drug	N-(5'-carboxypentyl)-1-deoxynojirimycin	PRSS1 PRSS2	9.00e-05	5	69	2	CID000133177
Drug	PTA-GPA	PRSS1 PRSS2	9.00e-05	5	69	2	CID000139330
Drug	propynyl benzoate	PRSS1 PRSS2	9.00e-05	5	69	2	CID000196666
Drug	M 93	PRSS1 PRSS2	9.00e-05	5	69	2	CID006444952
Drug	6-amidinoindole	PRSS1 PRSS2	9.00e-05	5	69	2	CID003018291
Drug	Ag-B	PRSS1 PRSS2	9.00e-05	5	69	2	CID000004286
Drug	beta-Neuroprotectin	PRSS1 PRSS2	9.00e-05	5	69	2	CID005748443
Drug	2,6-diphenoxypyridine	PRSS1 PRSS2	9.00e-05	5	69	2	CID000824772
Drug	AC1L3UIZ	PRSS1 PRSS2	9.00e-05	5	69	2	CID000147121
Drug	Ile-Phe-Lys-CH2Cl	PRSS1 PRSS2	9.00e-05	5	69	2	CID000124393
Drug	rho-guanidinobenzoate	PRSS1 PRSS2	9.00e-05	5	69	2	CID005311472
Drug	Meebdp	PRSS1 PRSS2	9.00e-05	5	69	2	CID000132560
Drug	Hc1	AMBP PRSS1 PRSS2	9.20e-05	29	69	3	CID011963785
Drug	S 2366	PRSS1 PRSS2 THBD	9.20e-05	29	69	3	CID000126364
Drug	20 alpha-hydroxycholesterol	AMBP PRSS1 PRSS2 ENPP1	1.13e-04	82	69	4	CID000121935
Drug	coproporphyrin III	AMBP PRSS1 PRSS2	1.24e-04	32	69	3	CID000114935
Drug	N-benzoyl-L-tyrosine thiobenzyl ester	PRSS1 PRSS2	1.35e-04	6	69	2	CID000191444
Drug	Ag2SO4	PRSS1 PRSS2	1.35e-04	6	69	2	CID000159275
Drug	N,N-dimethylglycylbenzocaine	PRSS1 PRSS2	1.35e-04	6	69	2	CID000188251
Drug	2 up	PRSS1 PRSS2	1.35e-04	6	69	2	CID000193409
Drug	N-benzoyltyrosine butylamide	PRSS1 PRSS2	1.35e-04	6	69	2	CID000125261
Drug	Circulin A	PRSS1 PRSS2	1.35e-04	6	69	2	CID000065155
Drug	azidobestatin	PRSS1 PRSS2	1.35e-04	6	69	2	CID000132261
Drug	2-azidoatrazine	PRSS1 PRSS2	1.35e-04	6	69	2	CID003032432
Drug	4-TAPAP	PRSS1 PRSS2	1.35e-04	6	69	2	CID000133476
Drug	3,4-dihydroquinazoline	CACNA1A CACNA1B	1.35e-04	6	69	2	CID000583065
Drug	Db04336	PRSS1 PRSS2	1.35e-04	6	69	2	CID000002014
Drug	alpha-sialylcholesterol	CACNA1A CACNA1B	1.35e-04	6	69	2	CID000133976
Drug	A61603	CACNA1A CACNA1B ADRA1D	1.36e-04	33	69	3	CID004038180
Drug	CNS 1145	CACNA1A CACNA1B RYR2	1.36e-04	33	69	3	CID000190902
Drug	IHC-64	CACNA1A CACNA1B RYR2	1.36e-04	33	69	3	CID000162753
Drug	NSC187724	PRSS1 PRSS2 THBD	1.63e-04	35	69	3	CID000426387
Drug	S-2238	PRSS1 PRSS2 THBD	1.77e-04	36	69	3	CID000123853
Drug	BTEE	PRSS1 PRSS2 NFKBIA	1.77e-04	36	69	3	CID000077033
Drug	diisopropyl	PRSS1 PRSS2 THBD	1.77e-04	36	69	3	CID000006589
Drug	isoproterenol	AMBP CACNA1A CACNA1B ADRA1D NAPEPLD AZIN2 PDLIM7 SCN7A RYR2	1.82e-04	669	69	9	CID000003779
Drug	riluzole	CACNA1A CACNA1B SCN7A NFASC RYR2	1.86e-04	174	69	5	CID000005070
Drug	Z-Glu-Tyr	PRSS1 PRSS2	1.88e-04	7	69	2	CID000096820
Drug	Kki 8	PRSS1 PRSS2	1.88e-04	7	69	2	CID000064584
Drug	O-4-(ethoxybutyl)berbamine	PRSS1 PRSS2	1.88e-04	7	69	2	CID000188375
Drug	APMPA	CACNA1A CACNA1B	1.88e-04	7	69	2	CID000512300
Drug	pentaammineaquocobalt(III) tetrafluoroborate	PRSS1 PRSS2	1.88e-04	7	69	2	CID000412963
Drug	bz-Ar	PRSS1 PRSS2	1.88e-04	7	69	2	CID000137302
Drug	bromobutide	PRSS1 PRSS2	1.88e-04	7	69	2	CID000053079
Drug	leupeptins	PRSS1 PRSS2	1.88e-04	7	69	2	CID003033938
Drug	Arg-OEt	PRSS1 PRSS2	1.88e-04	7	69	2	CID000439495
Drug	Inhibitor 61	PRSS1 PRSS2	1.88e-04	7	69	2	CID005327349
Drug	Kki 7	PRSS1 PRSS2	1.88e-04	7	69	2	CID003082667
Drug	Gly-Gly-Arg	PRSS1 PRSS2	1.88e-04	7	69	2	CID000133469
Disease	familial hemiplegic migraine 1 (implicated_via_orthology)	CACNA1A CACNA1B	1.57e-05	3	68	2	DOID:0111181 (implicated_via_orthology)
Disease	migraine (implicated_via_orthology)	CACNA1A CACNA1B	3.13e-05	4	68	2	DOID:6364 (implicated_via_orthology)
Disease	PANCREATITIS, HEREDITARY	PRSS1 PRSS2	5.21e-05	5	68	2	167800
Disease	Hereditary pancreatitis	PRSS1 PRSS2	5.21e-05	5	68	2	cv:C0238339
Disease	Autosomal Dominant Hereditary Pancreatitis	PRSS1 PRSS2	5.21e-05	5	68	2	C4080064
Disease	Hereditary pancreatitis	PRSS1 PRSS2	1.09e-04	7	68	2	C0238339
Disease	hereditary ataxia (implicated_via_orthology)	CACNA1A CACNA1B	1.09e-04	7	68	2	DOID:0050951 (implicated_via_orthology)
Disease	Pancreatitis, Chronic	PRSS1 PRSS2	1.86e-04	9	68	2	C0149521
Disease	acute kidney failure (is_implicated_in)	AMBP THBD	2.33e-04	10	68	2	DOID:3021 (is_implicated_in)
Disease	atopic dermatitis (implicated_via_orthology)	NFKBIA CTSE	2.84e-04	11	68	2	DOID:3310 (implicated_via_orthology)
Disease	epilepsy (implicated_via_orthology)	CACNA1A CACNA1B SCN7A NFASC	5.55e-04	163	68	4	DOID:1826 (implicated_via_orthology)
Disease	S-adenosylhomocysteine measurement	CACNA1B ADRA1D	6.96e-04	17	68	2	EFO_0010531
Disease	glioblastoma (is_implicated_in)	NFKBIA DMBT1	1.40e-03	24	68	2	DOID:3068 (is_implicated_in)
Disease	arachidonic acid measurement	CACNA1A ADRA1D	1.52e-03	25	68	2	EFO_0006808

Protein segments in the cluster

Peptide	Gene	Start	Entry
YCGVPGDGDEELLRF	AMBP	336	P02760
ERLDDTEPYFIGIFC	CACNA1A	131	O00555
TEPYFIGIFCFEAGI	CACNA1A	136	O00555
ALAFELSACFEYGPG	C8orf82	171	Q6P1X6
YCSGGELFDRIEPDI	CHEK1	86	O14757
VFGFGSKDDEYTLPC	ADGRF1	261	Q5T601
DLYFPEGCGVDIFAE	AZIN2	261	Q96A70
EGGEYETFTLDCPLF	DPH6	201	Q7L8W6
DDTEPYFIGIFCFEA	CACNA1B	131	Q00975
PLGAVDLYEYACGDE	PPP2R3B	556	Q9Y5P8
EGGVIVDYHGCDFFP	AK6	71	Q9Y3D8
YELVPCEGLFDEYLE	ANO7	696	Q6IWH7
LDDYDYELGECPEGV	MGA	386	Q8IWI9
DIEPGDEVTCFYGEG	KMT5C	206	Q86Y97
DIEPGEEISCYYGDG	KMT5B	296	Q4FZB7
FVDAEFDGILGLGYP	CTSE	176	P14091
DDDIFIACGPEKFRY	DCLK1	251	O15075
EVISNEGGRFCYPEF	PEAK1	216	Q9H792
REAGDGVFECEYYPV	FLNC	526	Q14315
DELPYDDCVFGGQRL	NFKBIA	301	P25963
GPVFDFDYDGRCDSL	ENPP1	796	P22413
FVEGLCFPDEGFSGL	PADI2	251	Q9Y2J8
EGLGDPACFYVGVIF	DPY19L2	236	Q6NUT2
LEKPNEGYLEFFVDC	EXOSC7	71	Q15024
EEGGFFEEKGAIFCP	PDLIM7	316	Q9NR12
GGRPEEYEGEYQCFA	NFASC	106	O94856
DDRTELPLFCYGGQD	BECN2	326	A8MW95
DCGKEGFVDLPEYPF	BHMT2	246	Q9H2M3
EDYCTPGAFELERLF	DUSP29	31	Q68J44
GFYPDELCSALFEGK	GCNT7	46	Q6ZNI0
SEPSIFLYGLECFEG	CRYBG2	1441	Q8N1P7
DFFGDDDVFIACGPE	DCX	241	O43602
IIAPEGYAAFYCDGE	BMP5	371	P22003
GGGIYEQDEFYELCD	MANBA	391	O00462
SFPDCYIAEFGDLEV	MARF1	1026	Q9Y4F3
DADVERFFNYCGLDP	FAM110B	271	Q8TC76
CVGLEPGEDAEEFYN	IQCB1	91	Q15051
LPYDLACTGGDFVLF	DCLRE1A	396	Q6PJP8
EGGCNYDYIEVFDGP	DMBT1	2056	Q9UGM3
AFKDFDVGDGFIPVC	RYR2	1191	Q92736
FAFVHDVCDDGLPYP	METTL8	251	Q9H825
EGLRDPACFYVGVIF	DPY19L2P2	46	Q6ZN68
CDRDAGVGFPEYQEE	IGF2R	731	P11717
GAVDEEVGDYFPEFL	RSBN1	481	Q5VWQ0
TGIPAGYCFVEFADL	TRNAU1AP	41	Q9NX07
VPFDDDDKIVGGYTC	PRSS3P2	16	Q8NHM4
ECPEGYILDDGFICT	THBD	426	P07204
VDCPTLEFEYGDADG	STRIP2	46	Q9ULQ0
EADCGYDYVELFDGL	TLL1	941	O43897
GCPEDVQGFLSYLEE	PTPN14	1081	Q15678
EYAAGGEIFSLCLPE	STK17B	111	O94768
EDLQGFGVCLDPVYD	MYCBP2	1121	O75592
PDERFCGITEEAGYA	ADRA1D	241	P25100
ERLGCSEEGPADEYY	CLHC1	36	Q8NHS4
LYFVDFGDNGDCPLK	TDRKH	386	Q9Y2W6
SKEVVELGFCYDPDG	KBTBD13	221	C9JR72
PEDYACGGSFFIQEK	SIDT1	266	Q9NXL6
APFDDDDKIVGGYIC	PRSS2	16	P07478
CEPTFLFYAGGELVA	NME9	81	Q86XW9
LPLCFVDYGVEALGE	TMEM245	126	Q9H330
GVLEFVADEGICYLP	UFD1	81	Q92890
DETLEYECFGGEYRP	USP24	2001	Q9UPU5
PFFTLDVECGGGFYI	TRUB1	241	Q8WWH5
GVDLFAGRFYECIDP	SCN7A	1076	Q01118
APFDDDDKIVGGYNC	PRSS1	16	P07477
GCDLIDSFALDEPFY	THBS2	166	P35442
IARCDENGFYFPGVV	VWA3B	1041	Q502W6
EAICEYPGFGEHLIA	ZNF329	61	Q86UD4
FAGDTGYCPAFEEIG	NAPEPLD	281	Q6IQ20
LEDEGVYICEFATFP	NECTIN1	116	Q15223