Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein-hormone receptor activity	LHCGR ADIPOR1 FSHR	1.04e-04	22	84	3	GO:0016500
GeneOntologyBiologicalProcess	regulation of cell size	SEMA4F FN1 DSCAM FSHR LRP1 MACF1 SLC12A5	3.44e-05	225	83	7	GO:0008361
GeneOntologyBiologicalProcess	cell surface receptor protein tyrosine kinase signaling pathway	DOCK3 DOK6 PRKD2 NDST1 MYOF ADIPOR1 GALNT3 FSHR LRP1 TEK PTPRT COL1A1	4.27e-05	747	83	12	GO:0007169
GeneOntologyBiologicalProcess	positive regulation of Rac protein signal transduction	FNTA LRP4 TEK	4.91e-05	18	83	3	GO:0035022
GeneOntologyBiologicalProcess	positive regulation of intracellular signal transduction	LHCGR DOK6 PRKD2 KSR1 NDST1 FN1 FNTA IKBKE FSHR LRP1 LRP4 STEAP3 SLC35B2 PLD2 ADGRV1 TEK	5.23e-05	1299	83	16	GO:1902533
GeneOntologyBiologicalProcess	regulation of axon extension	SEMA4F FN1 DSCAM LRP1 MACF1	6.29e-05	104	83	5	GO:0030516
GeneOntologyBiologicalProcess	positive regulation of axon extension	FN1 DSCAM LRP1 MACF1	7.11e-05	55	83	4	GO:0045773
GeneOntologyBiologicalProcess	regulation of axonogenesis	SEMA4F FN1 DSCAM LRP1 LRP4 MACF1	1.25e-04	192	83	6	GO:0050770
GeneOntologyBiologicalProcess	regulation of extent of cell growth	SEMA4F FN1 DSCAM LRP1 MACF1	1.34e-04	122	83	5	GO:0061387
GeneOntologyBiologicalProcess	axon extension	SEMA4F FN1 DSCAM LRP1 MACF1	2.15e-04	135	83	5	GO:0048675
GeneOntologyBiologicalProcess	enzyme-linked receptor protein signaling pathway	DOCK3 DOK6 PRKD2 NDST1 MYOF ADIPOR1 GALNT3 FNTA FSHR LRP1 LRP4 TEK PTPRT COL1A1	2.55e-04	1186	83	14	GO:0007167
GeneOntologyCellularComponent	synaptic membrane	SLC6A9 SEMA4F SUSD4 SLC4A8 KCNQ5 LRP1 LRP4 CLMP PTPRT SLC12A5	1.39e-04	583	86	10	GO:0097060
Domain	fn3	FNDC7 PTPRB FN1 DSCAM TEK PTPRT LRIT1	7.75e-06	162	83	7	PF00041
Domain	FN3	FNDC7 PTPRB FN1 DSCAM TEK PTPRT LRIT1	1.84e-05	185	83	7	SM00060
Domain	FN3	FNDC7 PTPRB FN1 DSCAM TEK PTPRT LRIT1	2.94e-05	199	83	7	PS50853
Domain	Ldl_recept_b	LRP1 LRP4 LRP5L	2.97e-05	14	83	3	PF00058
Domain	LDLRB	LRP1 LRP4 LRP5L	2.97e-05	14	83	3	PS51120
Domain	LY	LRP1 LRP4 LRP5L	3.70e-05	15	83	3	SM00135
Domain	LDLR_classB_rpt	LRP1 LRP4 LRP5L	3.70e-05	15	83	3	IPR000033
Domain	FN3_dom	FNDC7 PTPRB FN1 DSCAM TEK PTPRT LRIT1	4.02e-05	209	83	7	IPR003961
Domain	ConA-like_dom	TRIM64B THBS2 TRIM4 TRIM64 ADGRV1 PTPRT SPRYD4	5.40e-05	219	83	7	IPR013320
Domain	Ig-like_fold	HAVCR1 HHLA2 FNDC7 PTPRB HMCN2 FN1 DSCAM MYCBP2 CLMP TEK PTPRT LRIT1	6.41e-05	706	83	12	IPR013783
Domain	-	HAVCR1 HHLA2 FNDC7 PTPRB FN1 DSCAM MYCBP2 CLMP TEK PTPRT LRIT1	1.64e-04	663	83	11	2.60.40.10
Domain	Butyrophylin	TRIM64B TRIM4 TRIM64 SPRYD4	2.66e-04	70	83	4	IPR003879
Domain	Gphrmn_rcpt_fam	LHCGR FSHR	2.89e-04	6	83	2	IPR002131
Domain	ZF_BBOX	TRIM64B TRIM4 MYCBP2 TRIM64	4.44e-04	80	83	4	PS50119
Domain	Znf_B-box	TRIM64B TRIM4 MYCBP2 TRIM64	4.65e-04	81	83	4	IPR000315
Domain	EGF_CA	THBS2 HMCN2 LRP1 LRP4	5.84e-04	86	83	4	PF07645
Domain	SPRY	TRIM64B TRIM4 TRIM64 SPRYD4	6.10e-04	87	83	4	SM00449
Domain	-	LRP1 LRP4 LRP5L	6.89e-04	39	83	3	2.120.10.30
Domain	SPRY	TRIM64B TRIM4 TRIM64 SPRYD4	8.16e-04	94	83	4	PF00622
Domain	SPRY_dom	TRIM64B TRIM4 TRIM64 SPRYD4	8.16e-04	94	83	4	IPR003877
Domain	B30.2/SPRY	TRIM64B TRIM4 TRIM64 SPRYD4	8.49e-04	95	83	4	IPR001870
Domain	B302_SPRY	TRIM64B TRIM4 TRIM64 SPRYD4	8.49e-04	95	83	4	PS50188
Domain	LRR_5	LHCGR FSHR	8.58e-04	10	83	2	PF13306
Domain	LRR_5	LHCGR FSHR	8.58e-04	10	83	2	IPR026906
Domain	EGF_1	THBS2 HMCN2 FN1 LRP1 LRP4 TEK	9.58e-04	255	83	6	PS00022
Domain	EGF-like_CS	THBS2 HMCN2 FN1 LRP1 LRP4 TEK	1.08e-03	261	83	6	IPR013032
Domain	6-blade_b-propeller_TolB-like	LRP1 LRP4 LRP5L	1.12e-03	46	83	3	IPR011042
Domain	IG_LIKE	HAVCR1 HHLA2 HMCN2 DSCAM CLMP TEK PTPRT LRIT1	1.51e-03	491	83	8	PS50835
Domain	Ig-like_dom	HAVCR1 HHLA2 HMCN2 DSCAM CLMP TEK PTPRT LRIT1	1.76e-03	503	83	8	IPR007110
Domain	EGF_CA	THBS2 HMCN2 LRP1 LRP4	2.14e-03	122	83	4	SM00179
Domain	EGF-like_Ca-bd_dom	THBS2 HMCN2 LRP1 LRP4	2.27e-03	124	83	4	IPR001881
Domain	IG	HAVCR1 HHLA2 HMCN2 DSCAM CLMP PTPRT LRIT1	2.68e-03	421	83	7	SM00409
Domain	Ig_sub	HAVCR1 HHLA2 HMCN2 DSCAM CLMP PTPRT LRIT1	2.68e-03	421	83	7	IPR003599
Domain	BBOX	TRIM64B TRIM4 TRIM64	3.59e-03	69	83	3	SM00336
Domain	-	TRIM64B TRIM4 TRIM64	3.89e-03	71	83	3	4.10.45.10
Domain	EGF_3	THBS2 HMCN2 LRP1 LRP4 TEK	3.96e-03	235	83	5	PS50026
Domain	zf-B_box	TRIM64B TRIM4 TRIM64	4.05e-03	72	83	3	PF00643
Domain	AA-permease/SLC12A_dom	SLC7A2 SLC12A5	4.25e-03	22	83	2	IPR004841
Domain	AA_permease	SLC7A2 SLC12A5	4.25e-03	22	83	2	PF00324
Domain	Cupredoxin	PRPF8 F8	4.25e-03	22	83	2	IPR008972
Domain	IGv	HHLA2 DSCAM CLMP	4.54e-03	75	83	3	SM00406
Domain	EGF-like_dom	THBS2 HMCN2 LRP1 LRP4 TEK	5.05e-03	249	83	5	IPR000742
Domain	Growth_fac_rcpt_	HMCN2 LRP1 LRP4 TEK	5.16e-03	156	83	4	IPR009030
Domain	cEGF	LRP1 LRP4	5.92e-03	26	83	2	IPR026823
Domain	cEGF	LRP1 LRP4	5.92e-03	26	83	2	PF12662
Domain	Znf_RING_CS	TRIM64B TRIM4 TRIM64 RING1	6.02e-03	163	83	4	IPR017907
Domain	EGF_2	THBS2 HMCN2 LRP1 LRP4 TEK	6.54e-03	265	83	5	PS01186
Domain	VWC	THBS2 COL1A1	6.84e-03	28	83	2	PF00093
Domain	Znf_C3HC4_RING-type	TRIM64B TRIM4 TRIM64 RING1	7.26e-03	172	83	4	IPR018957
Pathway	WP_MIR5093P_ALTERATION_OF_YAP1ECM_AXIS	THBS2 FN1 COL1A1	6.31e-05	18	62	3	M39421
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DOCK3 PRKD2 NDST1 LARP6 FN1 ZNF473 DSCAM MYCBP2 LRP1 LRP4 MACF1 PRPF8 ZMYM5 TXNDC11	3.59e-06	1285	87	14	35914814
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DOCK3 RABL6 PRKD2 SEMA4F NDST1 MYOF MYCBP2 KLHL36 HELZ2 LRP4 STEAP3 MED12 COL1A1	3.63e-06	1105	87	13	35748872
Pubmed	Mechanisms of gonadotropin desensitization.	LHCGR FSHR	6.19e-06	2	87	2	11988313
Pubmed	Structural and functional analysis of the fibronectin-binding protein FNE from Streptococcus equi spp. equi.	FN1 COL1A1	6.19e-06	2	87	2	25290767
Pubmed	Evidence for chromosome 2p16.3 polycystic ovary syndrome susceptibility locus in affected women of European ancestry.	LHCGR FSHR	6.19e-06	2	87	2	23118426
Pubmed	Analysis of pituitary gonadotropin concentration in blood serum and immunolocalization and immunoexpression of follicle stimulating hormone and luteinising hormone receptors in ovaries of postmenopausal women.	LHCGR FSHR	6.19e-06	2	87	2	22207559
Pubmed	Myoferlin gene silencing decreases Tie-2 expression in vitro and angiogenesis in vivo.	MYOF TEK	6.19e-06	2	87	2	21586340
Pubmed	Cluster III of low-density lipoprotein receptor-related protein 1 binds activated blood coagulation factor VIII.	LRP1 F8	6.19e-06	2	87	2	25486042
Pubmed	Thrombospondin-2 is up-regulated by TGFβ2 and increases fibronectin expression in human trabecular meshwork cells.	THBS2 FN1	6.19e-06	2	87	2	31589839
Pubmed	Structural analysis of collagen type I interactions with human fibronectin reveals a cooperative binding mode.	FN1 COL1A1	6.19e-06	2	87	2	23653354
Pubmed	Association of human follitropin (FSH) receptor with splicing variant of human lutropin/choriogonadotropin receptor negatively controls the expression of human FSH receptor.	LHCGR FSHR	6.19e-06	2	87	2	15890674
Pubmed	The effect of splice variant of the human luteinizing hormone (LH) receptor on the expression of gonadotropin receptor.	LHCGR FSHR	6.19e-06	2	87	2	17092637
Pubmed	The Luteinizing Hormone Receptor Knockout Mouse as a Tool to Probe the In Vivo Actions of Gonadotropic Hormones/Receptors in Females.	LHCGR FSHR	6.19e-06	2	87	2	33605422
Pubmed	Tyrosine phosphatase beta regulates angiopoietin-Tie2 signaling in human endothelial cells.	PTPRB TEK	6.19e-06	2	87	2	19116766
Pubmed	Associations of FSHR and LHCGR gene variants with ovarian reserve and clinical pregnancy rates.	LHCGR FSHR	6.19e-06	2	87	2	34391684
Pubmed	Cloning and expression of a glycine transporter from mouse brain.	SLC6A9 COL1A1	6.19e-06	2	87	2	1618338
Pubmed	Evidence That Factor VIII Forms a Bivalent Complex with the Low Density Lipoprotein (LDL) Receptor-related Protein 1 (LRP1): IDENTIFICATION OF CLUSTER IV ON LRP1 AS THE MAJOR BINDING SITE.	LRP1 F8	6.19e-06	2	87	2	27794518
Pubmed	PRPF8 increases the aggressiveness of hepatocellular carcinoma by regulating FAK/AKT pathway via fibronectin 1 splicing.	FN1 PRPF8	6.19e-06	2	87	2	36609600
Pubmed	A common polymorphism decreases LRP1 mRNA stability and is associated with increased plasma factor VIII levels.	LRP1 F8	6.19e-06	2	87	2	28431990
Pubmed	Proteolytic cleavage of factor VIII heavy chain is required to expose the binding-site for low-density lipoprotein receptor-related protein within the A2 domain.	LRP1 F8	6.19e-06	2	87	2	16839343
Pubmed	Alterations of the FSH and LH receptor genes and evaluation of sperm ultrastructure in men with idiopathic hypergonadotropic hypogonadism.	LHCGR FSHR	6.19e-06	2	87	2	23884663
Pubmed	Breast cancer cells alter the dynamics of stromal fibronectin-collagen interactions.	FN1 COL1A1	6.19e-06	2	87	2	27503584
Pubmed	Factor VIII Interacts with the Endocytic Receptor Low-density Lipoprotein Receptor-related Protein 1 via an Extended Surface Comprising "Hot-Spot" Lysine Residues.	LRP1 F8	6.19e-06	2	87	2	25903134
Pubmed	Reduced Gonadotrophin Receptor Expression Is Associated with a More Aggressive Ovarian Cancer Phenotype.	LHCGR FSHR	6.19e-06	2	87	2	33374698
Pubmed	Leutinizing hormone/choriogonadotropin receptor and follicle stimulating hormone receptor gene variants in polycystic ovary syndrome.	LHCGR FSHR	6.19e-06	2	87	2	25649397
Pubmed	The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces.	FN1 LRP1	6.19e-06	2	87	2	11867643
Pubmed	[Regulation of collagen type I and fibronectin mRNA expression by mechanical stress in cultured human periodontal ligament fibroblasts].	FN1 COL1A1	6.19e-06	2	87	2	19031824
Pubmed	Constitutively active follicle-stimulating hormone receptor enables androgen-independent spermatogenesis.	LHCGR FSHR	6.19e-06	2	87	2	29584617
Pubmed	Intrinsic differences in the response of the human lutropin receptor versus the human follitropin receptor to activating mutations.	LHCGR FSHR	6.19e-06	2	87	2	17609213
Pubmed	LRP1 is required for novobiocin-mediated fibronectin turnover.	FN1 LRP1	6.19e-06	2	87	2	30061663
Pubmed	[Effect of Danshensu on fibronectin and collagen-1 secretion induced by high glucose in human peritoneal mesothelial cells].	FN1 COL1A1	6.19e-06	2	87	2	21311138
Pubmed	Zinc induces structural reorganization of gelatin binding domain from human fibronectin and affects collagen binding.	FN1 COL1A1	6.19e-06	2	87	2	20541508
Pubmed	The murine luteinizing hormone and follicle-stimulating hormone receptor genes: transcription initiation sites, putative promoter sequences and promoter activity.	LHCGR FSHR	6.19e-06	2	87	2	1459341
Pubmed	Targeting gonadotropin receptor genes: reproductive biology, aging, and related health implications.	LHCGR FSHR	6.19e-06	2	87	2	16034175
Pubmed	Gonadotropin receptor polymorphisms (FSHR N680S and LHCGR N312S) are not predictive of clinical outcome and live birth in assisted reproductive technology.	LHCGR FSHR	6.19e-06	2	87	2	35842313
Pubmed	Heterodimerization between the lutropin and follitropin receptors is associated with an attenuation of hormone-dependent signaling.	LHCGR FSHR	6.19e-06	2	87	2	23825122
Pubmed	Shear stress control of vascular leaks and atheromas through Tie2 activation by VE-PTP sequestration.	PTPRB TEK	6.19e-06	2	87	2	36740996
Pubmed	Targeting the vascular-specific phosphatase PTPRB protects against retinal ganglion cell loss in a pre-clinical model of glaucoma.	PTPRB TEK	6.19e-06	2	87	2	31621585
Pubmed	Infertility and ovarian follicle reserve depletion are associated with dysregulation of the FSH and LH receptor density in human antral follicles.	LHCGR FSHR	6.19e-06	2	87	2	28188844
Pubmed	FSH and LH receptors are differentially expressed in cumulus cells surrounding developmentally competent and incompetent mouse fully grown antral oocytes.	LHCGR FSHR	6.19e-06	2	87	2	24476692
Pubmed	Evidence for expression and functionality of FSH and LH/hCG receptors in human endometrium.	LHCGR FSHR	6.19e-06	2	87	2	29974367
Pubmed	Combined assessment of polymorphisms in the LHCGR and FSHR genes predict chance of pregnancy after in vitro fertilization.	LHCGR FSHR	6.19e-06	2	87	2	26769719
Pubmed	Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature.	PTPRB TEK	6.19e-06	2	87	2	25180601
Pubmed	Factor VIII bypasses CD91/LRP for endocytosis by dendritic cells leading to T-cell activation.	LRP1 F8	6.19e-06	2	87	2	18166789
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	NDST1 MYOF GALNT3 MYCBP2 P4HA1 TM9SF1 B3GALNT2 LRP1 LRP4 SLC35B2 POMT1 TXNDC11 COL1A1	8.90e-06	1201	87	13	35696571
Pubmed	Platelet-derived growth factor receptors direct vascular development independent of vascular smooth muscle cell function.	FN1 TEK COL1A1	1.20e-05	18	87	3	18606782
Pubmed	Lhx2-/- mice develop liver fibrosis.	FN1 P4HA1 COL1A1	1.42e-05	19	87	3	15536133
Pubmed	Heterogeneity of endothelial VE-PTP downstream polarization, Tie2 activation, junctional claudin-5, and permeability in the aorta and vena cava.	PTPRB TEK	1.85e-05	3	87	2	38032480
Pubmed	Triptorelin and cetrorelix induce immune responses and affect uterine development and expressions of genes and proteins of ESR1, LHR, and FSHR of mice.	LHCGR FSHR	1.85e-05	3	87	2	27075695
Pubmed	A mouse model of brittle cornea syndrome caused by mutation in Zfp469.	FN1 COL1A1	1.85e-05	3	87	2	34368841
Pubmed	Characterization of binding of LARP6 to the 5' stem-loop of collagen mRNAs: implications for synthesis of type I collagen.	LARP6 COL1A1	1.85e-05	3	87	2	25692237
Pubmed	VE-PTP controls blood vessel development by balancing Tie-2 activity.	PTPRB TEK	1.85e-05	3	87	2	19451274
Pubmed	The binding sites for the very low density lipoprotein receptor and low-density lipoprotein receptor-related protein are shared within coagulation factor VIII.	LRP1 F8	1.85e-05	3	87	2	18277139
Pubmed	Aetiological coding sequence variants in non-syndromic premature ovarian failure: From genetic linkage analysis to next generation sequencing.	LHCGR FSHR	1.85e-05	3	87	2	25960166
Pubmed	Interaction of the leucine-rich repeats of polycystin-1 with extracellular matrix proteins: possible role in cell proliferation.	FN1 COL1A1	1.85e-05	3	87	2	11752017
Pubmed	LH (Trp8Arg/Ile15Thr), LHR (insLQ) and FSHR (Asn680Ser) polymorphisms genotypic prevalence in women with endometriosis and infertility.	LHCGR FSHR	1.85e-05	3	87	2	25935136
Pubmed	Genetic polymorphisms of GnRH and gonadotrophic hormone receptors affect the phenotype of polycystic ovary syndrome.	LHCGR FSHR	1.85e-05	3	87	2	19403562
Pubmed	Hepatic remnant lipoprotein clearance by heparan sulfate proteoglycans and low-density lipoprotein receptors depend on dietary conditions in mice.	NDST1 LRP1	1.85e-05	3	87	2	23846497
Pubmed	Low density lipoprotein receptor-related protein-1 (LRP1) regulates thrombospondin-2 (TSP2) enhancement of Notch3 signaling.	THBS2 LRP1	1.85e-05	3	87	2	20472562
Pubmed	Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone-receptor interactions.	LHCGR FSHR	1.85e-05	3	87	2	8747461
Pubmed	Regulation of luteinizing hormone-receptor and follicle-stimulating hormone-receptor messenger ribonucleic acid levels during development in the neonatal mouse ovary.	LHCGR FSHR	1.85e-05	3	87	2	9282997
Pubmed	Macrophage LRP1 contributes to the clearance of von Willebrand factor.	LRP1 F8	1.85e-05	3	87	2	22234691
Pubmed	Collagen regulates the ability of endothelial progenitor cells to protect hypoxic myocardium through a mechanism involving miR-377/VE-PTP axis.	PTPRB COL1A1	1.85e-05	3	87	2	30044046
Pubmed	Identification and verification of FN1, P4HA1 and CREBBP as potential biomarkers in human atrial fibrillation.	FN1 P4HA1	1.85e-05	3	87	2	37161136
Pubmed	Metastatic outgrowth encompasses COL-I, FN1, and POSTN up-regulation and assembly to fibrillar networks regulating cell adhesion, migration, and growth.	FN1 COL1A1	1.85e-05	3	87	2	20489157
Pubmed	Contribution of low density lipoprotein receptor-related protein genotypes to coagulation factor VIII levels in thrombotic women.	LRP1 F8	1.85e-05	3	87	2	16956829
Pubmed	Mapping and Exploring the Collagen-I Proteostasis Network.	FN1 COL1A1	1.85e-05	3	87	2	26848503
Pubmed	Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors.	LHCGR FSHR	1.85e-05	3	87	2	11847099
Pubmed	Fascin1 suppresses RIG-I-like receptor signaling and interferon-β production by associating with IκB kinase ϵ (IKKϵ) in colon cancer.	IKBKE FSCN1	1.85e-05	3	87	2	29496994
Pubmed	Superoxide-induced Type I collagen secretion depends on prolyl 4-hydroxylases.	P4HA1 COL1A1	1.85e-05	3	87	2	32819558
Pubmed	Ras homolog enriched in striatum inhibits the functional activity of wild type thyrotropin, follicle-stimulating hormone, luteinizing hormone receptors and activating thyrotropin receptor mutations by altering their expression in COS-7 cells.	LHCGR FSHR	1.85e-05	3	87	2	17556863
Pubmed	Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity.	LHCGR FSHR	1.85e-05	3	87	2	15889138
Pubmed	Functional interaction of vascular endothelial-protein-tyrosine phosphatase with the angiopoietin receptor Tie-2.	PTPRB TEK	1.85e-05	3	87	2	10557082
Pubmed	The G-protein coupled estrogen receptor (GPER/GPR30) is a gonadotropin receptor dependent positive prognosticator in ovarian carcinoma patients.	LHCGR FSHR	1.85e-05	3	87	2	23951246
Pubmed	Inhibition of fibronectin binding and fibronectin-mediated cell adhesion to collagen by a peptide from the second type I repeat of thrombospondin.	FN1 COL1A1	1.85e-05	3	87	2	8468356
Pubmed	Vascular Endothelial Receptor Tyrosine Phosphatase: Identification of Novel Substrates Related to Junctions and a Ternary Complex with EPHB4 and TIE2.	PTPRB TEK	1.85e-05	3	87	2	31427368
Pubmed	[Expression and pathobiological significance of Col I, Col IV and Fn in laryngeal squamous cell carcinomas].	FN1 COL1A1	1.85e-05	3	87	2	20359090
Pubmed	Low density lipoprotein receptor-related protein and factor IXa share structural requirements for binding to the A3 domain of coagulation factor VIII.	LRP1 F8	1.85e-05	3	87	2	12522143
Pubmed	Gene Expression in Granulosa Cells From Small Antral Follicles From Women With or Without Polycystic Ovaries.	LHCGR FSHR	1.85e-05	3	87	2	31276164
Pubmed	Expression of mRNA for the LH and FSH receptors in mouse oocytes and preimplantation embryos.	LHCGR FSHR	1.85e-05	3	87	2	11226072
Pubmed	Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin.	PTPRB TEK	1.85e-05	3	87	2	26642851
Pubmed	Weighted correlation network analysis identifies FN1, COL1A1 and SERPINE1 associated with the progression and prognosis of gastric cancer.	FN1 COL1A1	1.85e-05	3	87	2	33780362
Pubmed	Association of gonadotropin receptor precursors with the protein folding chaperone calnexin.	LHCGR FSHR	1.85e-05	3	87	2	9528938
Pubmed	A genome-wide association study identified a novel genetic loci STON1-GTF2A1L/LHCGR/FSHR for bilaterality of neovascular age-related macular degeneration.	LHCGR FSHR	1.85e-05	3	87	2	28775256
Pubmed	A threshold concentration of FSH is needed during IVM of ex vivo collected human oocytes.	LHCGR FSHR	1.85e-05	3	87	2	34050448
Pubmed	Bioinformatics analysis identifies COL1A1, THBS2 and SPP1 as potential predictors of patient prognosis and immunotherapy response in gastric cancer.	THBS2 COL1A1	1.85e-05	3	87	2	33345281
Pubmed	Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair.	FN1 TEK COL1A1	2.95e-05	24	87	3	28237967
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK3 MYOF SLC4A8 ZNF473 HELZ2 MACF1 MED12 TMEM63A	3.38e-05	493	87	8	15368895
Pubmed	Interaction of endosialin/TEM1 with extracellular matrix proteins mediates cell adhesion and migration.	FN1 COL1A1	3.70e-05	4	87	2	17986615
Pubmed	The transforming growth factor-beta-inducible matrix protein (beta)ig-h3 interacts with fibronectin.	FN1 COL1A1	3.70e-05	4	87	2	12034705
Pubmed	Localization of types I and III collagen and fibronectin in the developing mouse palatal shelves.	FN1 COL1A1	3.70e-05	4	87	2	8984825
Pubmed	Influence of mutations affecting gonadotropin production or responsiveness on expression of inhibin subunit mRNA and protein in the mouse ovary.	LHCGR FSHR	3.70e-05	4	87	2	15232063
Pubmed	Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts.	FN1 COL1A1	3.70e-05	4	87	2	16049333
Pubmed	Lymphocyte CD44 binds the COOH-terminal heparin-binding domain of fibronectin.	FN1 COL1A1	3.70e-05	4	87	2	1730778
Pubmed	Fibronectin mediates mesendodermal cell fate decisions.	FN1 COL1A1	3.70e-05	4	87	2	23715551
Pubmed	Interactions between thrombospondin and the small proteoglycan decorin: interference with cell attachment.	FN1 COL1A1	3.70e-05	4	87	2	1468447
Pubmed	β-arrestins regulate gonadotropin receptor-mediated cell proliferation and apoptosis by controlling different FSHR or LHCGR intracellular signaling in the hGL5 cell line.	LHCGR FSHR	3.70e-05	4	87	2	27502035
Pubmed	Ca2+/calmodulin-dependent protein kinase IIβ and IIδ mediate TGFβ-induced transduction of fibronectin and collagen in human pulmonary fibroblasts.	FN1 COL1A1	3.70e-05	4	87	2	28130256
Pubmed	Thrombospondin-1 and thrombospondin-2 mRNA and TSP-1 and TSP-2 protein expression in uterine fibroids and correlation to the genes COL1A1 and COL3A1 and to the collagen cross-link hydroxyproline.	THBS2 COL1A1	3.70e-05	4	87	2	18089612
Pubmed	Activation of expression of genes coding for extracellular matrix proteins in Tat-producing glioblastoma cells.	FN1 COL1A1	3.70e-05	4	87	2	1409674
Cytoband	5q33.2	HAVCR1 MRPL22	4.19e-04	16	87	2	5q33.2
Cytoband	1q32.1	ADIPOR1 IKBKE LINC00862	1.16e-03	108	87	3	1q32.1
Cytoband	Ensembl 112 genes in cytogenetic band chr5q33	HAVCR1 NDST1 MRPL22	1.50e-03	118	87	3	chr5q33
Cytoband	11q14.3	TRIM64B TRIM64	1.70e-03	32	87	2	11q14.3
GeneFamily	Fibronectin type III domain containing	FNDC7 PTPRB FN1 DSCAM TEK PTPRT LRIT1	1.87e-06	160	66	7	555
GeneFamily	Glycoprotein hormone receptors	LHCGR FSHR	3.93e-05	3	66	2	199
GeneFamily	Immunoglobulin like domain containing	HMCN2 DSCAM CLMP TEK PTPRT	6.94e-04	193	66	5	594
GeneFamily	Low density lipoprotein receptors	LRP1 LRP4	9.97e-04	13	66	2	634
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRB PTPRT	2.64e-03	21	66	2	813
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HMCN2 DSCAM CLMP LRIT1	2.84e-03	161	66	4	593
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM64B TRIM4 TRIM64	5.06e-03	95	66	3	59
Coexpression	GSE40273_XBP1_KO_VS_WT_TREG_DN	SEMA4F HAVCR1 KSR1 NDST1 MYCBP2 HELZ2 PLD2 FSCN1	2.80e-07	199	85	8	M9124
CoexpressionAtlas	FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000_k-means-cluster#5	SLC6A9 SEMA4F MYOF SLC7A2 THBS2 MACF1 KCNAB3 COL1A1	1.25e-05	276	83	8	Facebase_RNAseq_e10.5_Olfactory Pit_1000_K5
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 NAALAD2 MYCBP2 VPS13C LRP1 STEAP3 COL1A1	1.01e-07	192	87	7	11088878043a6ff95ba1970361256a82e434b80a
ToppCell	facs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 NAALAD2 P4HA1 LRP1 STEAP3 CLMP COL1A1	1.05e-07	193	87	7	735a72fac16397edde95e8eefa6f83caeb5ee5df
ToppCell	facs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 NAALAD2 P4HA1 LRP1 STEAP3 CLMP COL1A1	1.05e-07	193	87	7	ff901d2f3d7a511639c1e3b76058896c0d8a8602
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYOF FN1 MYCBP2 LRP1 MACF1 CLMP COL1A1	1.29e-07	199	87	7	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYOF NAALAD2 FN1 LRP1 MACF1 CLMP COL1A1	1.29e-07	199	87	7	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	facs-Marrow-KLS-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK3 FNDC7 DSCAM CENPI PLD2 FSCN1	8.17e-07	163	87	6	b83a35c4426d66b5734a98fa6c72b345fe462030
ToppCell	facs-Marrow-KLS-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK3 FNDC7 DSCAM CENPI PLD2 FSCN1	8.17e-07	163	87	6	c20ca9b6b4170ebcb0e66eef3e5d8ebff22b1a91
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 NAALAD2 THNSL1 IKBKE SPRYD4 COL1A1	1.16e-06	173	87	6	ab6d3507301038f944ad59ccd848b5e6eeb76d04
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRB HMCN2 DSCAM FSCN1 TEK F8	1.28e-06	176	87	6	64e426f5e84884ce2c29acf6f4b958962a63927f
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FN1 LRP1 LRP4 STEAP3 MACF1 COL1A1	1.50e-06	181	87	6	091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FN1 LRP1 STEAP3 MACF1 CLMP COL1A1	1.55e-06	182	87	6	19c5e3a9d9b3728303b682102e276adfe93aa759
ToppCell	P28-Mesenchymal\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FN1 LRP1 LRP4 STEAP3 MACF1 COL1A1	1.55e-06	182	87	6	69f9d44694fe4f55a971ae0ac5dc3e7448ee78f3
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	MYOF SLC7A2 HMCN2 KCNQ5 FN1 B3GALNT2	1.60e-06	183	87	6	818fd886e0188091310825f9145fa53328f2c979
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FN1 LRP1 LRP4 STEAP3 MACF1 COL1A1	1.65e-06	184	87	6	924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	MYOF HMCN2 KCNQ5 FN1 B3GALNT2 MACF1	1.87e-06	188	87	6	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 LRP1 LRP4 MACF1 CLMP COL1A1	1.93e-06	189	87	6	324c81285c51f4f8bb1aef428b18fe2c549c2c11
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 LARP6 FN1 LRP1 CLMP COL1A1	1.99e-06	190	87	6	bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 LARP6 FN1 LRP1 CLMP COL1A1	1.99e-06	190	87	6	e275de94468872e70cf305b3b450823d4c9c5e3f
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 LARP6 FN1 LRP1 CLMP COL1A1	1.99e-06	190	87	6	ee2f4a55d2fd18b83e55399b5b5697a15a2d2e70
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYOF SLC7A2 THBS2 LRP1 CLMP COL1A1	1.99e-06	190	87	6	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 NAALAD2 LRP1 STEAP3 CLMP COL1A1	2.12e-06	192	87	6	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	LPS-IL1RA-Stromal_mesenchymal\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYOF SLC7A2 THBS2 LRP1 CLMP COL1A1	2.12e-06	192	87	6	4e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 NAALAD2 LRP1 STEAP3 CLMP COL1A1	2.12e-06	192	87	6	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	facs-Heart-RV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 NAALAD2 P4HA1 LRP1 CLMP COL1A1	2.18e-06	193	87	6	76f0f8569255d6cdf1e3b8e954cae72e71f87157
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAALAD2 FN1 LRP1 STEAP3 CLMP COL1A1	2.18e-06	193	87	6	160691b671710be10220803d788c2c961c236af1
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	THBS2 HMCN2 FN1 LRP1 CLMP COL1A1	2.25e-06	194	87	6	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYOF THBS2 FN1 P4HA1 CLMP COL1A1	2.31e-06	195	87	6	78cfde21dde4b877fc76c8b0d5ddaabe44b912d7
ToppCell	PCW_07-8.5-Mesenchymal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOK6 NAALAD2 FN1 LRP1 CLMP COL1A1	2.38e-06	196	87	6	8e10802f52e5e1853ea4ad34bf9a32a34e6112b5
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOK6 NAALAD2 FN1 LRP1 MACF1 COL1A1	2.38e-06	196	87	6	1450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	THBS2 LARP6 FN1 LRP4 CLMP COL1A1	2.46e-06	197	87	6	2ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 NAALAD2 MYCBP2 P4HA1 LRP1 COL1A1	2.46e-06	197	87	6	cfd4cc5fb8d7a60dd5c0d2a1a7bad7ba38c19d40
ToppCell	Mesenchymal_cells-Arteriolar_fibro.\|Mesenchymal_cells / Lineage and Cell class	THBS2 HMCN2 FN1 LRP1 STEAP3 COL1A1	2.46e-06	197	87	6	cb321836980e7b4efbb9284c6af7ccd34079d2be
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	THBS2 LARP6 FN1 LRP4 CLMP COL1A1	2.53e-06	198	87	6	9d61483b0decac2fe90045b3474843360b2c49b3
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DOK6 NAALAD2 FN1 LRP1 MACF1 COL1A1	2.53e-06	198	87	6	17dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCell	COVID-19-kidney-Fibroblast-2\|kidney / Disease (COVID-19 only), tissue and cell type	SLC7A2 THBS2 FN1 LRP1 CLMP COL1A1	2.53e-06	198	87	6	ca26ca460856b1faaa3e83766da6abdf63af2b51
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	THBS2 LARP6 FN1 LRP4 CLMP COL1A1	2.53e-06	198	87	6	bc9c9f2c87282b5ef8514773e065d2a6b5dde338
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-3\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	THBS2 HMCN2 ZNF728 CLMP TEK COL1A1	2.60e-06	199	87	6	07b8c33342c62afd9c63ec2d757cfa3ba65d2a98
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DOCK3 DSCAM LRP1 LRP4 TEK PTPRT	2.60e-06	199	87	6	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS2 LARP6 FN1 LRP1 CLMP COL1A1	2.68e-06	200	87	6	933b5b400e48a511ba0a056be1d33d3610b5f10d
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYOF FN1 LRP1 MACF1 CLMP COL1A1	2.68e-06	200	87	6	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	390C-Fibroblasts-Fibroblast-H-\|390C / Donor, Lineage, Cell class and subclass (all cells)	THBS2 LARP6 FN1 LRP1 CLMP COL1A1	2.68e-06	200	87	6	ec7d6a08e34bcad5b3bbff56ebef96ae17e4cefd
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS2 LARP6 FN1 LRP1 CLMP COL1A1	2.68e-06	200	87	6	cfea2f9d85646c9b722150551ff2e8fc4f6cc98a
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOK6 THBS2 FN1 LRP1 CLMP COL1A1	2.68e-06	200	87	6	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS2 LARP6 FN1 LRP1 CLMP COL1A1	2.68e-06	200	87	6	6f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-4\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	DOK6 THBS2 HMCN2 FN1 CLMP COL1A1	2.68e-06	200	87	6	54b18c92daaa3b3368c0c46134b0c27e10c8dbb0
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYOF FN1 LRP1 MACF1 CLMP COL1A1	2.68e-06	200	87	6	44a68bacdb3d5bf563bd35952176995850933a81
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS2 LARP6 FN1 LRP1 CLMP COL1A1	2.68e-06	200	87	6	3a164e3971bcd62b148b813171c103adb81f972e
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOK6 THBS2 FN1 LRP1 CLMP COL1A1	2.68e-06	200	87	6	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	MYOF MYCBP2 LRP1 MACF1 CLMP COL1A1	2.68e-06	200	87	6	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYOF FN1 LRP1 MACF1 CLMP COL1A1	2.68e-06	200	87	6	dc61016c61729f69649cfb21f6264e685ce83dea
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS2 LARP6 FN1 LRP1 CLMP COL1A1	2.68e-06	200	87	6	f6cf98aad53aa8b3fa02cf874d6f7cd75530a213
ToppCell	390C-Fibroblasts-Fibroblast-H\|390C / Donor, Lineage, Cell class and subclass (all cells)	THBS2 LARP6 FN1 LRP1 CLMP COL1A1	2.68e-06	200	87	6	671e731977c58a0c44c36b56422085d93d999aad
ToppCell	5'-Adult-LargeIntestine-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS2 LARP6 FN1 LRP1 CLMP COL1A1	2.68e-06	200	87	6	5a87bb8eb1c6bd2fbc357e1528e15ba1c0051438
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC7 PTPRB HELZ2 FSCN1 TEK	1.34e-05	155	87	5	59035d792c26d870a8b097939e97fa47859ba68c
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBS2 DSCAM CENPI KCNAB3 COL1A1	1.51e-05	159	87	5	7ed659163f45e0c4df4782997c0786900c8186c8
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1\|E16.5-samps / Age Group, Lineage, Cell class and subclass	FN1 VPS13C LRP1 MACF1 CLMP	1.71e-05	163	87	5	f1ec2625b52664308968b01d8e0275e1e0751480
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP4 KCNAB3 F8 SLC12A5 COL1A1	1.97e-05	168	87	5	d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 NAALAD2 FN1 LRP1 COL1A1	2.03e-05	169	87	5	bb43abad2c049b7f4d307737347290e01b3339a3
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 NAALAD2 FN1 LRP1 COL1A1	2.03e-05	169	87	5	5f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 NAALAD2 FN1 LRP1 COL1A1	2.03e-05	169	87	5	8bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOK6 DSCAM ADGRV1 TMC5 PTPRT	2.03e-05	169	87	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HAVCR1 FNDC7 SLC4A8 DSCAM FSCN1	2.40e-05	175	87	5	91cb819a1786020713b7e64480de0545380daae9
ToppCell	facs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 LRP1 LRP4 CLMP COL1A1	2.47e-05	176	87	5	c0a084f7a8645262d61971f094689e02bf15b113
ToppCell	facs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 LRP1 LRP4 CLMP COL1A1	2.47e-05	176	87	5	cccf9201f6e2da7524b911a5961d3b227edab222
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	THBS2 NAALAD2 FN1 LRP1 COL1A1	2.47e-05	176	87	5	2e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	THBS2 NAALAD2 FN1 LRP1 COL1A1	2.47e-05	176	87	5	f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	THBS2 FN1 LRP1 CLMP COL1A1	2.60e-05	178	87	5	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LHCGR THBS2 LRP1 CLMP COL1A1	2.75e-05	180	87	5	c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LHCGR THBS2 LRP1 CLMP COL1A1	2.75e-05	180	87	5	32c6a3886428d82fb4355d987c6d2645f333447b
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB MYCBP2 MACF1 TEK F8	2.75e-05	180	87	5	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB MYCBP2 MACF1 TEK F8	2.75e-05	180	87	5	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS2 LARP6 FN1 CLMP COL1A1	2.82e-05	181	87	5	e1ae9ada60ec89e7a7cde9c231c1a099ed2ffecc
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOK6 THBS2 NAALAD2 STEAP3 COL1A1	2.82e-05	181	87	5	269b39ac65790061d54eab47a8eeb024403f0348
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOK6 THBS2 NAALAD2 STEAP3 COL1A1	2.82e-05	181	87	5	cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 FN1 LRP1 CLMP COL1A1	2.82e-05	181	87	5	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOK6 THBS2 NAALAD2 STEAP3 COL1A1	2.82e-05	181	87	5	c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 FN1 LRP1 CLMP COL1A1	2.82e-05	181	87	5	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 FN1 STEAP3 TEK COL1A1	2.97e-05	183	87	5	5cfcd589a480e67654d3d94e71916f122150db10
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 FN1 STEAP3 TEK COL1A1	2.97e-05	183	87	5	c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 FN1 STEAP3 TEK COL1A1	2.97e-05	183	87	5	81003ddc24164959dd41bb12fcac72638789b8f2
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	MYOF HMCN2 KCNQ5 FN1 B3GALNT2	2.97e-05	183	87	5	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THBS2 FN1 LRP1 CLMP COL1A1	3.05e-05	184	87	5	01257e5c12e38b849fd3d9496c43ded666249ba5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 NAALAD2 LRP1 CLMP COL1A1	3.05e-05	184	87	5	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 FN1 STEAP3 TEK COL1A1	3.13e-05	185	87	5	3cd0686a14e734a0f243070ab939adcb4c454478
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 FN1 STEAP3 TEK COL1A1	3.13e-05	185	87	5	00258f458cbf6d36449db95528a6b5038d731d2d
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 FN1 STEAP3 TEK COL1A1	3.13e-05	185	87	5	a94694e226856bc5b168464f52d76004145717a5
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	THBS2 HMCN2 FN1 LRP1 CLMP	3.13e-05	185	87	5	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FN1 LRP1 STEAP3 MACF1 COL1A1	3.13e-05	185	87	5	46460e74cc613df9043f5404e7342aa13cc34873
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THBS2 CLMP PTPRT SLC12A5 COL1A1	3.21e-05	186	87	5	4e983de6d2515082f9e555f4f949cec84281c140
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAALAD2 LARP6 LRP1 CLMP COL1A1	3.21e-05	186	87	5	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FN1 LRP1 STEAP3 MACF1 COL1A1	3.21e-05	186	87	5	88e6246172d816806a498a5c1f38e699f2f5d7c2
ToppCell	facs-Pancreas-Exocrine-24m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 LARP6 STEAP3 CLMP COL1A1	3.30e-05	187	87	5	0f90bce2087aecfdbb377e6f46c6e468efbb6e28
ToppCell	facs-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 LARP6 STEAP3 CLMP COL1A1	3.30e-05	187	87	5	76c957b2976d38adb45e07bcf96c689442e1fc20
ToppCell	facs-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 LARP6 STEAP3 CLMP COL1A1	3.30e-05	187	87	5	90a1078b0303799fba5d2ca4fa12076fd75b78b1
ToppCell	P15-Mesenchymal\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FN1 LRP1 STEAP3 MACF1 COL1A1	3.38e-05	188	87	5	f1ba0b661621a65c91432e62ba73531bdf18e7c1
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	FN1 LRP1 LRP4 MACF1 COL1A1	3.38e-05	188	87	5	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	HMCN2 FN1 LRP1 STEAP3 COL1A1	3.38e-05	188	87	5	409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 NAALAD2 LARP6 LRP1 COL1A1	3.47e-05	189	87	5	544d95df910f1b276995624509a7e41b219baca0
ToppCell	EC-Sinusoidal_ECs\|World / Lineage and Cell class	SUSD4 PTPRB FSCN1 TEK F8	3.47e-05	189	87	5	9a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 FN1 LRP1 STEAP3 COL1A1	3.47e-05	189	87	5	bc54ffd7bd1627a36747a80ce5139e4a69928400
Drug	fibrostatin C	FN1 P4HA1 COL1A1	2.40e-06	8	81	3	CID000056296
Drug	Aconitine [302-27-2]; Down 200; 6.2uM; MCF7; HT_HG-U133A	MYOF SLC4A8 LARP6 DSCAM IKBKE PLD2 TMEM63A	6.61e-06	197	81	7	6797_DN
Drug	Picotamide monohydrate [80530-63-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A	TRAPPC11 MYOF LARP6 FN1 PLD2 LRP5L TMEM63A	6.61e-06	197	81	7	6787_DN
Drug	Diflorasone Diacetate [33564-31-7]; Up 200; 8uM; MCF7; HT_HG-U133A	HAVCR1 KSR1 SLC7A2 NAALAD2 PTPRB FN1 KCNAB3	6.83e-06	198	81	7	4158_UP
Drug	Choriogonadotropin alfa	LHCGR FSHR	1.25e-05	2	81	2	DB00097
Drug	Menotropins	LHCGR FSHR	1.25e-05	2	81	2	DB00032
Drug	ethyl methacrylate	SEMA4F FN1 F8	2.35e-05	16	81	3	CID000007343
Drug	celastrol; Up 200; 2.5uM; MCF7; HT_HG-U133A_EA	MRPL18 LARP6 ZNF473 LRP5L ZMYM5 COL1A1	3.35e-05	171	81	6	887_UP
Drug	MDL 27044	FN1 COL1A1	3.74e-05	3	81	2	CID000125537
Drug	A-FN	LHCGR FN1 FSHR	4.03e-05	19	81	3	CID005287635
Drug	MDL 27,032	PRKD2 FN1 COL1A1	5.51e-05	21	81	3	CID000163812
Drug	Trifluoperazine dihydrochloride [440-17-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A	SLC6A9 FN1 NIPSNAP3B KCNAB3 COL1A1 TMEM63A	5.68e-05	188	81	6	5442_UP
Drug	Amiodarone hydrochloride [19774-82-4]; Down 200; 5.8uM; PC3; HT_HG-U133A	SLC4A8 ZNF473 LRP5L FSCN1 COL1A1 TMEM63A	6.76e-05	194	81	6	4657_DN
Drug	Levonordefrin [829-74-3]; Down 200; 21.8uM; PC3; HT_HG-U133A	NDST1 POMT1 F8 MED12 ZMYM5 COL1A1	6.76e-05	194	81	6	5854_DN
Drug	Harmaline hydrochloride dihydrate [6027-98-1]; Up 200; 14uM; MCF7; HT_HG-U133A	FN1 ACTL8 LRP4 MED12 COL1A1 TMEM63A	6.96e-05	195	81	6	2805_UP
Drug	Meptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; HL60; HT_HG-U133A	MYOF FN1 KLHL36 TMC5 KCNAB3 COL1A1	6.96e-05	195	81	6	2906_UP
Drug	Sulfadoxine [2447-57-6]; Down 200; 12.8uM; MCF7; HT_HG-U133A	NDST1 ACTL8 ZNF473 CENPI FSCN1 MED12	7.16e-05	196	81	6	3547_DN
Drug	Progesterone [57-83-0]; Up 200; 12.8uM; PC3; HT_HG-U133A	HAVCR1 PTPRB DSCAM LRP4 COL1A1 TMEM63A	7.16e-05	196	81	6	6646_UP
Drug	Dropropizine (R,S) [17692-31-8]; Up 200; 17uM; PC3; HT_HG-U133A	MYOF THNSL1 LRP1 LRP4 COL1A1 TMEM63A	7.36e-05	197	81	6	5106_UP
Drug	chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A	SLC6A9 ACTL8 ZNF473 IKBKE FSCN1 TMEM63A	7.36e-05	197	81	6	6936_UP
Drug	Etanidazole [22668-01-5]; Up 200; 18.6uM; MCF7; HT_HG-U133A	LARP6 ACTL8 DSCAM VPS13C FSCN1 TMEM63A	7.36e-05	197	81	6	6211_UP
Drug	Benfotiamine [22457-89-2]; Up 200; 8.6uM; HL60; HT_HG-U133A	SEMA4F MYOF THBS2 PTPRB DSCAM KLHL36	7.36e-05	197	81	6	2177_UP
Drug	Ciprofloxacin hydrochloride [93107-08-5]; Down 200; 10.8uM; HL60; HG-U133A	MYOF GALNT3 VPS13C MACF1 LRP5L COL1A1	7.36e-05	197	81	6	2022_DN
Drug	IWR-1 compound	FN1 COL1A1	7.47e-05	4	81	2	ctd:C585534
Drug	Iobenguane sulfate; Up 200; 10.8uM; MCF7; HT_HG-U133A	DOCK3 NAALAD2 LARP6 LRP5L COL1A1 TMEM63A	7.57e-05	198	81	6	2878_UP
Drug	Diprophylline [479-18-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A	SLC4A8 NIPSNAP3B IKBKE PLD2 TMC5 TMEM63A	7.57e-05	198	81	6	1689_UP
Drug	Acebutolol hydrochloride [34381-68-5]; Down 200; 10.8uM; MCF7; HT_HG-U133A	SEMA4F ACTL8 NIPSNAP3B IKBKE LRP5L TMEM63A	7.57e-05	198	81	6	4976_DN
Drug	2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A	NDST1 ZNF473 IKBKE FSCN1 MED12 SLC12A5	7.57e-05	198	81	6	6969_UP
Drug	Denatonium benzoate [3734-33-6]; Down 200; 9uM; MCF7; HT_HG-U133A	SEMA4F MYOF DSCAM IKBKE CENPI TMEM63A	7.57e-05	198	81	6	6502_DN
Drug	(1)-Nipecotic acid [498-95-3]; Down 200; 31uM; MCF7; HT_HG-U133A	MYOF THNSL1 DSCAM KLHL36 STEAP3 TMEM63A	7.57e-05	198	81	6	6500_DN
Drug	Ornidazole [16773-42-5]; Up 200; 18.2uM; PC3; HT_HG-U133A	SEMA4F FN1 LRP4 TEK COL1A1 TMEM63A	7.57e-05	198	81	6	5064_UP
Drug	Foliosidine [2520-38-9]; Up 200; 13uM; PC3; HT_HG-U133A	KSR1 GALNT3 DSCAM LRP1 COL1A1 TMEM63A	7.57e-05	198	81	6	3739_UP
Drug	Dosulepin hydrochloride [897-15-4]; Up 200; 12uM; MCF7; HT_HG-U133A	MYOF SLC7A2 NAALAD2 LARP6 FSCN1 TMEM63A	7.78e-05	199	81	6	5986_UP
Drug	Epiandrosterone [481-29-8]; Up 200; 13.8uM; MCF7; HT_HG-U133A	KSR1 SLC7A2 DSCAM VPS13C TEK COL1A1	7.78e-05	199	81	6	5687_UP
Drug	Cinnarizine [298-57-7]; Down 200; 10.8uM; PC3; HT_HG-U133A	RABL6 MYOF ZNF473 FSCN1 COL1A1 TMEM63A	7.78e-05	199	81	6	5817_DN
Drug	CAY10397; Up 200; 10uM; MCF7; HT_HG-U133A	RABL6 MYOF THNSL1 CENPI SLC12A5 TMEM63A	8.00e-05	200	81	6	7082_UP
Drug	rosiglitazone; Down 200; 10uM; MCF7; HT_HG-U133A	SEMA4F LARP6 ACTL8 KLHL36 LRP5L ZMYM5	8.00e-05	200	81	6	5230_DN
Drug	Org 41841	LHCGR FSHR	1.24e-04	5	81	2	ctd:C510603
Drug	tetrahydrofurfuryl methacrylate	FN1 F8	1.24e-04	5	81	2	CID000017151
Disease	Aortic Valve Insufficiency	FN1 COL1A1	3.93e-04	11	80	2	C0003504
Disease	granulosa cell tumor (is_marker_for)	LHCGR FSHR	3.93e-04	11	80	2	DOID:2999 (is_marker_for)
Disease	congenital diaphragmatic hernia (implicated_via_orthology)	NDST1 LRP1	4.71e-04	12	80	2	DOID:3827 (implicated_via_orthology)
Disease	MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2K	B3GALNT2 POMT1	6.47e-04	14	80	2	C1836373
Disease	alpha-Dystroglycanopathies	B3GALNT2 POMT1	6.47e-04	14	80	2	C2936406
Disease	Muscle eye brain disease	B3GALNT2 POMT1	6.47e-04	14	80	2	C0457133
Disease	Fukuyama Type Congenital Muscular Dystrophy	B3GALNT2 POMT1	6.47e-04	14	80	2	C0410174
Disease	Muscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies) Type A, 1	B3GALNT2 POMT1	6.47e-04	14	80	2	C4284790
Disease	Walker-Warburg congenital muscular dystrophy	B3GALNT2 POMT1	7.45e-04	15	80	2	C0265221
Disease	amyloid-beta measurement, Alzheimer's disease biomarker measurement	HAVCR1 FNDC7	8.50e-04	16	80	2	EFO_0005194, EFO_0006514
Disease	osteoporosis	DOK6 GALNT3 ADGRV1	1.04e-03	73	80	3	EFO_0003882
Disease	Hemangiosarcoma	PTPRB TEK	1.08e-03	18	80	2	C0018923
Disease	IgA glomerulonephritis (is_marker_for)	HAVCR1 FN1	1.34e-03	20	80	2	DOID:2986 (is_marker_for)
Disease	snoring measurement	KCNQ5 MACF1 ADGRV1	1.56e-03	84	80	3	EFO_0008341
Disease	Epilepsy, Benign Psychomotor, Childhood	TEK SLC12A5	1.77e-03	23	80	2	C0393672
Disease	Epilepsy, Lateral Temporal	TEK SLC12A5	1.77e-03	23	80	2	C0393682
Disease	Uncinate Epilepsy	TEK SLC12A5	1.77e-03	23	80	2	C0014558
Disease	Epilepsy, Temporal Lobe	TEK SLC12A5	1.77e-03	23	80	2	C0014556
Disease	Left Ventricular Hypertrophy	FN1 COL1A1	2.09e-03	25	80	2	C0149721
Disease	response to norepinephrine-dopamine reuptake inhibitor	KCNQ5 ADGRV1	2.26e-03	26	80	2	EFO_0007870
Disease	Hyalinosis, Segmental Glomerular	HAVCR1 FN1	2.62e-03	28	80	2	C0086432

Protein segments in the cluster

Peptide	Gene	Start	Entry
SVWLGASVVAHLSTY	ACTL8	336	Q9H568
GTVRIWHSSTYRLES	COPB2	251	P35606
YWVVLSSHGERESKL	ADGRV1	856	Q8WXG9
LTTYGVHAITRLEAW	SLC7A2	511	P52569
TSIHWSYKTTDDIVK	RABL6	81	Q3YEC7
RKYVLWVVTHSGDLS	PTPRB	1236	P23467
KSIFRIHTETGNIWT	ADIPOR1	126	Q96A54
ISESSKVYRWADHSS	KLHL36	16	Q8N4N3
TLTVITLERWHTITY	LHCGR	456	P22888
TGLKAATWYEITIRS	FNDC7	81	Q5VTL7
GLWSIKVYSSGRHSV	HMCN2	291	Q8NDA2
TWSRKHLYLETSSKE	LIPJ	91	Q5W064
GSHRDIFVTSKTVLW	LRP1	686	Q07954
GSVVYAHSKELITAW	KCNQ5	256	Q9NR82
TVDLWSIGVTLYHAA	IKBKE	201	Q14164
DIGLSVTHRFSTKSW	KSR1	341	Q8IVT5
SSFERGSEVVIHWKY	HHLA2	51	Q9UM44
HLRTSYSELVGFWSV	NIPSNAP3B	61	Q9BS92
WSIRVTSTEEYPHLK	NDST1	451	P52848
STTLREGWVVHYSNK	PRKD2	396	Q9BZL6
RSLYWTHTGTEHIEV	LRP5L	46	A4QPB2
LTRDWRTTAHALKYS	LARP6	141	Q9BRS8
ALVWHYSLTDSRIKT	MED12	376	Q93074
RLHYSGSINAWSTKE	F8	2071	P00451
HSRELYTSKWTVTFA	TMEM63A	386	O94886
VVGDTYHSVSLVWKA	LRIT1	436	Q9P2V4
ISAWLHSVLESYLRT	MACF1	1686	Q9UPN3
VSWIEQYTTIHGKSA	MFSD4B	341	Q5TF39
ILKEVEYRTTTGTWA	PTPRT	321	O14522
EYRTTTGTWAETHIV	PTPRT	326	O14522
GDLETVHYRISKSAW	P4HA1	371	P13674
SEHKYSSSPLEWVTL	POMT1	561	Q9Y6A1
FKSLWIERTTLTLTH	DOCK3	1471	Q8IZD9
AFRTHTGKYWTLTAT	FSCN1	306	Q16658
TLSKSISLPRSAYWH	DOK6	256	Q6PKX4
TRTSYRIGDTWSKKD	FN1	236	P02751
EAWSTLLRTVHSVLY	GALNT3	196	Q14435
WKSTHYDVVVGVLSA	B3GALNT2	46	Q8NCR0
SKRTTGYWSHSIQFL	HSDL1	286	Q3SXM5
SVYTLTAITLERWHT	FSHR	456	P23945
NSVSKLIHYVGWLST	CENPI	531	Q92674
SSITKSQGSEWRYVL	HELZ2	2546	Q9BYK8
SWNGSRTHYVDSVKR	IGHV3-16	71	A0A0C4DH30
RHGTSLEIWLGYVTS	PIWIL3	256	Q7Z3Z3
SKTWELSLYELHRTP	RING1	11	Q06587
WYGSTVFLHVRTSIK	OR6F1	251	Q8NGZ6
LWSSYLTKGVIVERS	SLC12A5	381	Q9H2X9
SYIHTSASLDISRKW	MRPL22	31	Q9NWU5
SKGWRRSSYVITTKI	KCNAB3	146	O43448
WTTAQRTSLSKSYIL	DSCAM	1521	O60469
TVHLSYLTVTTLWSF	TAS2R50	171	P59544
KLYHSWLLVGSRTEV	SEMA4F	491	O95754
TAVTSGRHYWEVTVK	SPRYD4	81	Q8WW59
WRYIGRSLQSKHSTE	FNTA	356	P49354
IVWTNGTHVTYRKDT	HAVCR1	61	Q96D42
YWETFPSISHLLKIT	LINC00862	6	A6NCI5
HRWTSLELVKGTYTT	MYCBP2	1791	O75592
ERWSKPYVATLSLHS	SLC4A8	151	Q2Y0W8
VGITLFTVSHRKSLW	ABCD3	616	P28288
SGRYVWSHVILKVLV	CLMP	116	Q9H6B4
TSHTGAWGKTVIEYK	COL1A1	1416	P02452
AVAVYTTTVHWLESR	PRPF8	806	Q6P2Q9
GVATGHYIISWKRTS	TRAPPC11	976	Q7Z392
STLHTLTYGWTRAFE	STEAP3	406	Q658P3
EHWEYLTATLISIGV	SLC35B2	236	Q8TB61
STHETLLTTWKIVAF	SUSD4	311	Q5VX71
KISSTRFETDVIHWY	TRGV10	41	A0A0A0MS01
NWSSALTYKRIHTGE	ZNF728	211	P0DKX0
STREWAIKKHLYSTR	MRPL18	106	Q9H0U6
TSLAESVLKVWHGAY	SLC6A9	51	P48067
ELRKSWYSTHSLVGD	THNSL1	41	Q8IYQ7
TTYISWKEELHRSRE	VPS13C	2606	Q709C8
RVATTASVIYKIWEH	TEX50	136	A0A1B0GTY4
THSSAVISWTILDGY	TEK	651	Q02763
VSFTGEWHLETKIYV	TXNDC11	276	Q6PKC3
GEKTTRSWLLYSTSK	ZMYM5	571	Q9UJ78
HSIYSWIDTLSTRPG	TMC5	876	Q6UXY8
LTYWIDGTRHVVSLE	THBS2	126	P35442
TSGKHYWEVESRDSL	TRIM4	376	Q9C037
TSGKHYWEVDVTLSS	TRIM64	336	A6NGJ6
LVVAVGSSLHSYIWD	WDCP	171	Q9H6R7
TSGKHYWEVDVTLSS	TRIM64B	336	A6NI03
LYSVRLTHGDFSWTT	PLD2	86	O14939
EFLGLTHTYSVRWSE	TM9SF1	196	O15321
KSFSGSYRLTQHWIT	ZNF473	216	Q8WTR7
VHDKLYWTDSGTSRI	LRP4	521	O75096
HVYWTDVSTDTISRA	LRP4	786	O75096
ETTTSVRYHQSIRWK	NAALAD2	36	Q9Y3Q0
HTKPVVTLTSYWEDI	MYOF	636	Q9NZM1