Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP2 LRP1B LRP8 SORL1

6.50e-1016174GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP2 LRP1B LRP8 SORL1

2.13e-0921174GO:0030228
GeneOntologyMolecularFunctioncalcium ion binding

LRP2 LTBP4 LRP1B HSPG2 THBS1 LRP8 HMCN2 SCUBE2

6.80e-08749178GO:0005509
GeneOntologyMolecularFunctioncargo receptor activity

LRP2 LRP1B LRP8 SORL1

6.98e-0785174GO:0038024
GeneOntologyMolecularFunctionlipoprotein particle binding

THBS1 LRP8 SORL1

3.30e-0635173GO:0071813
GeneOntologyMolecularFunctionprotein-lipid complex binding

THBS1 LRP8 SORL1

3.30e-0635173GO:0071814
GeneOntologyMolecularFunctioncollagen V binding

HSPG2 THBS1

6.81e-065172GO:0070052
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LTBP4 HSPG2 THBS1 HMCN2

1.65e-05188174GO:0005201
GeneOntologyMolecularFunctionamyloid-beta binding

HSPG2 LRP8 SORL1

8.35e-05102173GO:0001540
GeneOntologyMolecularFunctionlow-density lipoprotein particle binding

THBS1 SORL1

1.04e-0418172GO:0030169
GeneOntologyMolecularFunctiontransforming growth factor beta binding

LTBP4 THBS1

2.19e-0426172GO:0050431
GeneOntologyMolecularFunctiongrowth factor binding

LRP2 LTBP4 THBS1

2.93e-04156173GO:0019838
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor binding

LRP2 HSPG2

3.77e-0434172GO:0050750
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

LRP2 HSPG2

4.96e-0439172GO:0070325
GeneOntologyMolecularFunctionamide binding

HSPG2 LRP8 SORL1

1.93e-03299173GO:0033218
GeneOntologyMolecularFunctioncollagen binding

HSPG2 THBS1

2.12e-0381172GO:0005518
GeneOntologyMolecularFunctionpeptide binding

HSPG2 LRP8 SORL1

2.31e-03318173GO:0042277
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

GPR162 LTBP4 LRP8 SORL1 HMCN2

4.41e-031353175GO:0004888
GeneOntologyMolecularFunctionstructural molecule activity

LTBP4 HSPG2 THBS1 HMCN2

5.88e-03891174GO:0005198
GeneOntologyMolecularFunctionSH3 domain binding

LRP2 ADAM19

6.45e-03143172GO:0017124
GeneOntologyMolecularFunctioncytokine binding

LTBP4 THBS1

7.73e-03157172GO:0019955
GeneOntologyMolecularFunctionintegrin binding

LTBP4 THBS1

9.53e-03175172GO:0005178
GeneOntologyMolecularFunctionendopeptidase inhibitor activity

THBS1 SORL1

1.01e-02180172GO:0004866
GeneOntologyMolecularFunctionprotease binding

HSPG2 THBS1

1.02e-02181172GO:0002020
GeneOntologyMolecularFunctionpeptidase inhibitor activity

THBS1 SORL1

1.08e-02187172GO:0030414
GeneOntologyMolecularFunctionendopeptidase regulator activity

THBS1 SORL1

1.24e-02201172GO:0061135
GeneOntologyMolecularFunctionpeptidase regulator activity

THBS1 SORL1

1.98e-02257172GO:0061134
GeneOntologyMolecularFunctionglycosaminoglycan binding

LTBP4 THBS1

2.14e-02268172GO:0005539
GeneOntologyBiologicalProcessendocytosis

LRP2 LRP1B HSPG2 THBS1 VAV2 LRP8 SORL1

2.22e-06827177GO:0006897
GeneOntologyBiologicalProcesscartilage development involved in endochondral bone morphogenesis

HSPG2 THBS1 SCUBE2

7.37e-0647173GO:0060351
GeneOntologyBiologicalProcessimport into cell

LRP2 LRP1B HSPG2 THBS1 VAV2 LRP8 SORL1

1.25e-051074177GO:0098657
GeneOntologyBiologicalProcessendochondral bone morphogenesis

HSPG2 THBS1 SCUBE2

3.54e-0579173GO:0060350
GeneOntologyBiologicalProcessprotein maturation

LTBP4 CORIN THBS1 ADAM19 SORL1

1.10e-04619175GO:0051604
GeneOntologyBiologicalProcessbone morphogenesis

HSPG2 THBS1 SCUBE2

1.36e-04124173GO:0060349
GeneOntologyBiologicalProcessreceptor-mediated endocytosis

LRP2 LRP1B HSPG2 SORL1

1.41e-04337174GO:0006898
GeneOntologyBiologicalProcessconnective tissue development

HSPG2 THBS1 SORL1 SCUBE2

1.51e-04343174GO:0061448
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

LRP2 LTBP4 THBS1 SORL1

1.58e-04347174GO:0090092
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

LRP2 THBS1 SORL1

2.38e-04150173GO:0090288
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

LRP2 LTBP4 THBS1 SORL1

3.04e-04412174GO:0090287
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

LRP2 LTBP4 THBS1 SORL1

4.07e-04445174GO:0141091
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

LRP2 LTBP4 THBS1 LRP8 SORL1

4.80e-04850175GO:0071363
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

LRP2 LTBP4 THBS1 SORL1

5.50e-04482174GO:0007178
GeneOntologyBiologicalProcessresponse to growth factor

LRP2 LTBP4 THBS1 LRP8 SORL1

5.72e-04883175GO:0070848
GeneOntologyBiologicalProcesscartilage development

HSPG2 THBS1 SCUBE2

9.72e-04243173GO:0051216
GeneOntologyBiologicalProcessbone development

HSPG2 THBS1 SCUBE2

1.23e-03264173GO:0060348
GeneOntologyBiologicalProcessskeletal system morphogenesis

HSPG2 THBS1 SCUBE2

1.42e-03277173GO:0048705
GeneOntologyBiologicalProcessprotein processing

CORIN THBS1 ADAM19

1.54e-03285173GO:0016485
GeneOntologyBiologicalProcessaxon guidance

LRP2 HSPG2 HMCN2

1.54e-03285173GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

LRP2 HSPG2 HMCN2

1.55e-03286173GO:0097485
GeneOntologyBiologicalProcessamyloid precursor protein catabolic process

ADAM19 SORL1

1.62e-0373172GO:0042987
GeneOntologyCellularComponentcell surface

LRP2 CORIN THBS1 GPC5 ADAM19 LRP8 SORL1 SCUBE2

9.81e-071111178GO:0009986
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LTBP4 HSPG2 THBS1 GPC5 ADAM19 HMCN2

2.52e-06530176GO:0062023
GeneOntologyCellularComponentextracellular matrix

LTBP4 HSPG2 THBS1 GPC5 ADAM19 HMCN2

8.59e-06656176GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LTBP4 HSPG2 THBS1 GPC5 ADAM19 HMCN2

8.75e-06658176GO:0030312
MousePhenoabnormal heart left ventricle morphology

LRP2 LTBP4 HSPG2 VAV2 ADAM19 HMCN2

1.33e-06369156MP:0003921
MousePhenocardiac hypertrophy

LRP2 LTBP4 CORIN VAV2 ADAM19

1.38e-06196155MP:0001625
MousePhenoabnormal aorta morphology

LRP2 LTBP4 HSPG2 VAV2 ADAM19

2.72e-06225155MP:0000272
MousePhenoabnormal heart ventricle morphology

LRP2 LTBP4 HSPG2 THBS1 VAV2 ADAM19 HMCN2

7.93e-06793157MP:0005294
MousePhenoheart right ventricle hypertrophy

LRP2 LTBP4 ADAM19

1.12e-0542153MP:0000276
MousePhenoabnormal systemic artery morphology

LRP2 LTBP4 HSPG2 VAV2 ADAM19

1.18e-05304155MP:0011655
MousePhenoabnormal heart right ventricle morphology

LRP2 LTBP4 HSPG2 ADAM19

1.85e-05156154MP:0003920
MousePhenoabnormal heart right ventricle wall morphology

LRP2 LTBP4 ADAM19

2.14e-0552153MP:0031534
MousePhenoincreased heart right ventricle size

LRP2 LTBP4 ADAM19

2.54e-0555153MP:0010563
MousePhenoincreased heart ventricle size

LRP2 LTBP4 VAV2 ADAM19

2.91e-05175154MP:0008772
MousePhenovascular smooth muscle hyperplasia

THBS1 VAV2

4.81e-0510152MP:0005489
MousePhenoabnormal artery morphology

LRP2 LTBP4 HSPG2 VAV2 ADAM19

6.98e-05440155MP:0002191
MousePhenoabnormal heart right ventricle size

LRP2 LTBP4 ADAM19

7.25e-0578153MP:0010577
MousePhenoabnormal vascular smooth muscle morphology

THBS1 VAV2 ADAM19

7.53e-0579153MP:0005592
MousePhenoabnormal heart ventricle size

LRP2 LTBP4 VAV2 ADAM19

8.17e-05228154MP:0031543
MousePhenoabnormal cardiac muscle tissue morphology

LRP2 LTBP4 HSPG2 VAV2 ADAM19

1.15e-04489155MP:0010630
MousePhenodecreased chondrocyte proliferation

HSPG2 SCUBE2

1.28e-0416152MP:0014101
MousePhenoabnormal chondrocyte proliferation

HSPG2 SCUBE2

2.02e-0420152MP:0014099
MousePhenoabnormal smooth muscle morphology

THBS1 VAV2 ADAM19

2.18e-04113153MP:0000767
MousePhenoabnormal heart ventricle wall morphology

LRP2 LTBP4 VAV2 ADAM19

2.24e-04296154MP:0031532
MousePhenoenlarged heart

LRP2 LTBP4 CORIN VAV2 DDHD1 ADAM19

2.33e-04916156MP:0000274
MousePhenoabnormal cardiac outflow tract development

LRP2 HSPG2 ADAM19

3.60e-04134153MP:0006126
MousePhenoabnormal interventricular septum morphology

LRP2 LTBP4 THBS1 ADAM19

3.88e-04342154MP:0000281
MousePhenohairpin sperm flagellum

DDHD1 LRP8

4.29e-0429152MP:0009243
MousePhenoincreased systemic arterial blood pressure

CORIN THBS1 VAV2

5.83e-04158153MP:0002842
MousePhenoabnormal heart septum morphology

LRP2 LTBP4 THBS1 ADAM19

6.26e-04388154MP:0006113
MousePhenoaneurysm

HSPG2 ADAM19

6.27e-0435152MP:0003279
MousePhenoabnormal muscle morphology

LRP2 LTBP4 HSPG2 THBS1 VAV2 ADAM19

6.49e-041106156MP:0002108
MousePhenooverexpanded pulmonary alveolus

LRP2 LTBP4

7.00e-0437152MP:0001183
MousePhenoemphysema

LRP2 LTBP4

7.00e-0437152MP:0001958
MousePhenoabnormal muscle fiber morphology

LTBP4 HSPG2 THBS1 VAV2

7.42e-04406154MP:0004087
MousePhenoabnormal aorta tunica media morphology

LTBP4 VAV2

7.78e-0439152MP:0009873
MousePhenoabnormal myocardium layer morphology

LRP2 LTBP4 HSPG2 VAV2

7.98e-04414154MP:0005329
MousePhenoabnormal heart layer morphology

LRP2 LTBP4 HSPG2 VAV2

8.58e-04422154MP:0010545
MousePhenoabnormal chondrocyte physiology

HSPG2 SCUBE2

9.03e-0442152MP:0009780
MousePhenoabnormal heart size

LRP2 LTBP4 CORIN VAV2 DDHD1 ADAM19

9.17e-041180156MP:0005406
MousePhenoabnormal cartilage physiology

HSPG2 SCUBE2

9.46e-0443152MP:0031306
MousePhenoincreased mean systemic arterial blood pressure

THBS1 VAV2

9.46e-0443152MP:0004875
MousePhenoabnormal pulmonary valve morphology

HSPG2 ADAM19

1.04e-0345152MP:0002748
MousePhenoabnormal heart and great artery attachment

LRP2 HSPG2 ADAM19

1.24e-03205153MP:0010426
MousePhenoabnormal aorta wall morphology

LTBP4 VAV2

1.28e-0350152MP:0009866
MousePhenoabnormal heart and great vessel attachment

LRP2 HSPG2 ADAM19

1.29e-03208153MP:0010425
MousePhenolung hemorrhage

HSPG2 THBS1

1.38e-0352152MP:0001182
MousePhenoincreased myocardial fiber size

LTBP4 VAV2

1.43e-0353152MP:0004564
MousePhenoabnormal heart right ventricle outflow tract morphology

HSPG2 ADAM19

1.43e-0353152MP:0010428
MousePhenokinked sperm flagellum

DDHD1 LRP8

1.60e-0356152MP:0009237
MousePhenohypertension

CORIN VAV2

1.60e-0356152MP:0000231
MousePhenoabnormal systemic arterial blood pressure

CORIN THBS1 VAV2

2.07e-03245153MP:0000230
MousePhenoheart left ventricle hypertrophy

LRP2 VAV2

2.15e-0365152MP:0002625
MousePhenoabnormal myocardium compact layer morphology

LRP2 HSPG2

2.28e-0367152MP:0004056
MousePhenoabnormal long bone epiphyseal plate proliferative zone

HSPG2 SCUBE2

2.35e-0368152MP:0003662
MousePhenoabnormal aorticopulmonary septum morphology

LRP2 ADAM19

2.35e-0368152MP:0010650
MousePhenoaorticopulmonary septal defect

LRP2 ADAM19

2.35e-0368152MP:0010651
MousePhenoabnormal snout morphology

LRP2 HSPG2 SORL1

2.37e-03257153MP:0000443
MousePhenoabnormal pulmonary circulation

HSPG2 THBS1

2.42e-0369152MP:0002295
MousePhenoabnormal aortic valve morphology

HSPG2 ADAM19

2.63e-0372152MP:0002747
MousePhenoabnormal heart left ventricle outflow tract morphology

HSPG2 ADAM19

2.63e-0372152MP:0010429
MousePhenoabnormal blood vessel morphology

LRP2 LTBP4 HSPG2 THBS1 VAV2 ADAM19

2.92e-031472156MP:0001614
MousePhenoabnormal skin physiology

LTBP4 HSPG2 THBS1

3.28e-03288153MP:0005501
MousePhenoabnormal chondrocyte morphology

HSPG2 SCUBE2

3.48e-0383152MP:0000166
MousePhenoabnormal truncus arteriosus septation

LRP2 ADAM19

3.56e-0384152MP:0010454
MousePhenoperimembraneous ventricular septal defect

LRP2 ADAM19

4.25e-0392152MP:0010418
DomainEGF_3

LRP2 LTBP4 LRP1B HSPG2 THBS1 ADAM19 LRP8 SORL1 HMCN2 SCUBE2

1.48e-152351710PS50026
DomainEGF-like_dom

LRP2 LTBP4 LRP1B HSPG2 THBS1 ADAM19 LRP8 SORL1 HMCN2 SCUBE2

2.65e-152491710IPR000742
DomainEGF-like_CS

LRP2 LTBP4 LRP1B HSPG2 THBS1 ADAM19 LRP8 SORL1 HMCN2 SCUBE2

4.27e-152611710IPR013032
DomainEGF_2

LRP2 LTBP4 LRP1B HSPG2 THBS1 ADAM19 LRP8 SORL1 HMCN2 SCUBE2

4.97e-152651710PS01186
DomainEGF_CA

LRP2 LTBP4 LRP1B HSPG2 THBS1 LRP8 HMCN2 SCUBE2

6.08e-14122178SM00179
DomainEGF-like_Ca-bd_dom

LRP2 LTBP4 LRP1B HSPG2 THBS1 LRP8 HMCN2 SCUBE2

6.94e-14124178IPR001881
DomainEGF_1

LRP2 LTBP4 LRP1B HSPG2 THBS1 ADAM19 LRP8 HMCN2 SCUBE2

3.16e-13255179PS00022
DomainEGF_CA

LRP2 LTBP4 LRP1B THBS1 LRP8 HMCN2 SCUBE2

6.41e-1386177PF07645
DomainLDLR_class-A_CS

LRP2 LRP1B HSPG2 CORIN LRP8 SORL1

7.93e-1340176IPR023415
DomainLdl_recept_a

LRP2 LRP1B HSPG2 CORIN LRP8 SORL1

1.68e-1245176PF00057
Domain-

LRP2 LRP1B HSPG2 CORIN LRP8 SORL1

1.93e-12461764.10.400.10
DomainLDLRA_1

LRP2 LRP1B HSPG2 CORIN LRP8 SORL1

2.52e-1248176PS01209
DomainLDrepeatLR_classA_rpt

LRP2 LRP1B HSPG2 CORIN LRP8 SORL1

2.87e-1249176IPR002172
DomainLDLa

LRP2 LRP1B HSPG2 CORIN LRP8 SORL1

2.87e-1249176SM00192
DomainLDLRA_2

LRP2 LRP1B HSPG2 CORIN LRP8 SORL1

2.87e-1249176PS50068
DomainEGF

LRP2 LTBP4 LRP1B HSPG2 THBS1 LRP8 SORL1 SCUBE2

1.23e-11235178SM00181
DomainGrowth_fac_rcpt_

LRP2 LTBP4 LRP1B HSPG2 LRP8 HMCN2 SCUBE2

4.49e-11156177IPR009030
DomainEGF_Ca-bd_CS

LRP2 LTBP4 LRP1B LRP8 HMCN2 SCUBE2

1.98e-1097176IPR018097
DomainEGF_CA

LRP2 LTBP4 LRP1B LRP8 HMCN2 SCUBE2

2.25e-1099176PS01187
DomainASX_HYDROXYL

LRP2 LTBP4 LRP1B LRP8 HMCN2 SCUBE2

2.39e-10100176PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP2 LTBP4 LRP1B LRP8 HMCN2 SCUBE2

3.41e-10106176IPR000152
DomainLdl_recept_b

LRP2 LRP1B LRP8 SORL1

4.67e-1014174PF00058
DomainLDLRB

LRP2 LRP1B LRP8 SORL1

4.67e-1014174PS51120
DomainLY

LRP2 LRP1B LRP8 SORL1

6.37e-1015174SM00135
DomainLDLR_classB_rpt

LRP2 LRP1B LRP8 SORL1

6.37e-1015174IPR000033
Domain-

LRP2 LRP1B LRP8 SORL1

3.79e-08391742.120.10.30
DomainEGF

LRP2 LRP1B HSPG2 LRP8 SCUBE2

7.48e-08126175PF00008
Domain6-blade_b-propeller_TolB-like

LRP2 LRP1B LRP8 SORL1

7.49e-0846174IPR011042
DomaincEGF

LRP2 LRP1B SCUBE2

1.61e-0626173IPR026823
DomaincEGF

LRP2 LRP1B SCUBE2

1.61e-0626173PF12662
DomainEGF_extracell

LRP2 LRP1B ADAM19

2.08e-0560173IPR013111
DomainEGF_2

LRP2 LRP1B ADAM19

2.08e-0560173PF07974
DomainLaminin_G

HSPG2 THBS1

1.25e-0358172IPR001791
Domain-

HSPG2 THBS1

3.31e-03951722.60.120.200
DomainIg_I-set

HSPG2 HMCN2

1.27e-02190172IPR013098
DomainI-set

HSPG2 HMCN2

1.27e-02190172PF07679
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP2 HSPG2 GPC5 LRP8

1.15e-0748144M27642
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

LRP2 HSPG2 GPC5 LRP8

2.26e-06100144M27158
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP2 GPC5 LRP8

1.08e-0545143MM15344
PathwayREACTOME_RELEASE_OF_HH_NP_FROM_THE_SECRETING_CELL

GPC5 SCUBE2

1.92e-057142MM15187
PathwayREACTOME_RELEASE_OF_HH_NP_FROM_THE_SECRETING_CELL

GPC5 SCUBE2

2.56e-058142M27444
PathwayREACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS

LRP2 HSPG2 GPC5 LRP8

3.38e-05198144M18311
PathwayREACTOME_DEFECTIVE_EXT2_CAUSES_EXOSTOSES_2

HSPG2 GPC5

8.28e-0514142M27263
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

LRP2 GPC5 LRP8

9.29e-0592143MM14881
PathwayREACTOME_ATTACHMENT_AND_ENTRY

HSPG2 GPC5

1.55e-0419142M41729
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LTBP4 HSPG2 THBS1 ADAM19

1.70e-04300144M610
PathwayREACTOME_DEFECTIVE_B4GALT7_CAUSES_EDS_PROGEROID_TYPE

HSPG2 GPC5

1.72e-0420142M27258
PathwayREACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_RSV_ATTACHMENT_AND_ENTRY

HSPG2 GPC5

2.29e-0423142M48234
PathwayREACTOME_HS_GAG_DEGRADATION

HSPG2 GPC5

2.50e-0424142M636
PathwayREACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS

HSPG2 GPC5

2.94e-0426142M708
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

HSPG2 THBS1 GPC5

3.43e-04143143M27275
PathwayREACTOME_HS_GAG_BIOSYNTHESIS

HSPG2 GPC5

4.19e-0431142M685
PathwayWP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES

LRP2 LRP1B LRP8 SORL1

4.24e-04381144M48063
PathwayREACTOME_EARLY_SARS_COV_2_INFECTION_EVENTS

HSPG2 GPC5

5.98e-0437142M45028
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_GLYCOSAMINOGLYCAN_METABOLISM

HSPG2 GPC5

7.35e-0441142M27257
PathwayREACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS

LRP2 GPC5 LRP8

7.74e-04189143MM14772
PathwayREACTOME_SENSORY_PERCEPTION

LRP2 GPC5 LRP8

7.86e-04190143MM15687
PathwayREACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM

HSPG2 GPC5

1.09e-0350142M678
PathwayREACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM

HSPG2 GPC5

1.42e-0357142M692
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

HSPG2 THBS1

1.52e-0359142M27218
PathwayREACTOME_HEDGEHOG_LIGAND_BIOGENESIS

GPC5 SCUBE2

1.67e-0362142MM15181
PathwayREACTOME_DISEASES_OF_METABOLISM

HSPG2 THBS1 GPC5

1.74e-03250143M27554
PathwayREACTOME_HEDGEHOG_LIGAND_BIOGENESIS

GPC5 SCUBE2

1.84e-0365142M27439
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LTBP4 THBS1 ADAM19

1.90e-03258143MM14572
PathwayREACTOME_SENSORY_PERCEPTION

LRP2 HSPG2 GPC5 LRP8

2.86e-03636144M41834
PathwayKEGG_ECM_RECEPTOR_INTERACTION

HSPG2 THBS1

3.05e-0384142M7098
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

HSPG2 THBS1

3.12e-0385142M16441
PathwayWP_COMPLEMENT_SYSTEM

LRP2 THBS1

3.96e-0396142M39581
PathwayREACTOME_RSV_HOST_INTERACTIONS

HSPG2 GPC5

4.12e-0398142M48247
PathwayREACTOME_AMYLOID_FIBER_FORMATION

HSPG2 SORL1

5.16e-03110142M27958
PathwayREACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_PATHWAY

HSPG2 GPC5

6.12e-03120142M48233
PathwayREACTOME_GLYCOSAMINOGLYCAN_METABOLISM

HSPG2 GPC5

6.72e-03126142M695
PathwayREACTOME_SIGNALING_BY_HEDGEHOG

GPC5 SCUBE2

7.90e-03137142MM15182
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

LTBP4 HSPG2 THBS1 ADAM19 HMCN2

1.42e-0816717522159717
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

LRP2 LRP1B LRP8

1.28e-072117321337463
Pubmed

Loss of apolipoprotein E receptor LR11 in Alzheimer disease.

LRP8 SORL1

2.25e-07217215313836
Pubmed

Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study.

LRP2 LRP1B GPC5

4.77e-073217325189868
Pubmed

Megalin mediates selenoprotein P uptake by kidney proximal tubule epithelial cells.

LRP2 LRP8

6.74e-07317218174160
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

LTBP4 HSPG2 THBS1 HMCN2

6.80e-0714617427068509
Pubmed

Selenoprotein P and apolipoprotein E receptor-2 interact at the blood-brain barrier and also within the brain to maintain an essential selenium pool that protects against neurodegeneration.

LRP2 LRP8

1.35e-06417224760755
Pubmed

Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.

LRP2 THBS1

1.35e-0641727775583
Pubmed

Maternal-fetal transfer of selenium in the mouse.

LRP2 LRP8

1.35e-06417223651543
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

LTBP4 HSPG2 THBS1 HMCN2

1.40e-0617517428071719
Pubmed

Thrombospondin-1 binds to ApoER2 and VLDL receptor and functions in postnatal neuronal migration.

THBS1 LRP8

2.25e-06517218946489
Pubmed

ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association.

LRP2 LRP8

2.25e-06517216101684
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP2 SORL1

2.25e-06517219047013
Pubmed

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

LRP2 LRP8

4.72e-06717212169628
Pubmed

Disruption of anterior segment development by TGF-beta1 overexpression in the eyes of transgenic mice.

HSPG2 THBS1

4.72e-06717212242711
Pubmed

Polymorphisms in the transforming growth factor beta 1 pathway in relation to colorectal cancer progression.

LTBP4 THBS1

4.72e-06717219998449
Pubmed

Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.

LRP8 SORL1

8.08e-06917220005821
Pubmed

SPARC, a secreted protein associated with cellular proliferation, inhibits cell spreading in vitro and exhibits Ca+2-dependent binding to the extracellular matrix.

HSPG2 THBS1

1.23e-05111722745554
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP2 LRP1B

1.23e-051117224639464
Pubmed

Localisation of specific heparan sulfate proteoglycans during the proliferative phase of brain development.

HSPG2 GPC5

1.48e-051217212761845
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

LRP2 LRP1B LRP8

1.57e-0510117323382219
Pubmed

Proteomics characterization of extracellular space components in the human aorta.

LTBP4 HSPG2 THBS1

1.57e-0510117320551380
Pubmed

Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis.

HSPG2 GPC5

2.04e-051417237408198
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

LRP2 LRP8

2.04e-051417217389516
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

LRP2 LRP1B

2.04e-051417215082773
Pubmed

No replication of genetic association between candidate polymorphisms and Alzheimer's disease.

HSPG2 SORL1

2.69e-051617219889475
Pubmed

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

LRP2 LRP8

3.42e-051817210827173
Pubmed

Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones.

HSPG2 GPC5

4.70e-052117226116392
Pubmed

Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly.

HSPG2 SORL1

5.16e-052217218448648
Pubmed

Loss of Hs3st3a1 or Hs3st3b1 enzymes alters heparan sulfate to reduce epithelial morphogenesis and adult salivary gland function.

HSPG2 THBS1

6.17e-052417234653670
Pubmed

Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.

THBS1 ADAM19

7.84e-052717224586749
Pubmed

Lung epithelial branching program antagonizes alveolar differentiation.

HSPG2 THBS1

1.18e-043317224058167
Pubmed

The spatiotemporal expression pattern of Syndecans in murine embryonic teeth.

HSPG2 GPC5

1.25e-043417232220631
Pubmed

Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfate.

HSPG2 GPC5

1.48e-043717232201365
Pubmed

Extracellular Hsp90α and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1.

HSPG2 THBS1

2.10e-044417231273033
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

LRP1B HSPG2 THBS1 LRP8 SORL1

2.13e-04120117535696571
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

LTBP4 HSPG2 THBS1

2.26e-0424817324006456
Pubmed

Congenital Diaphragmatic Hernia Overview

LRP2 LTBP4

2.30e-044617220301533
Pubmed

Protein profile of exosomes from trabecular meshwork cells.

HSPG2 THBS1

2.61e-044917221362503
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

HSPG2 THBS1

2.72e-045017223658023
Pubmed

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.

THBS1 ADAM19

4.18e-046217228344315
Pubmed

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1.

LTBP4 HSPG2

4.45e-046417236369321
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

HSPG2 THBS1

4.45e-046417222261194
InteractionNTN5 interactions

LRP2 LTBP4 LRP1B SORL1

2.79e-0924164int:NTN5
InteractionZNF517 interactions

LRP2 LTBP4 LRP1B SORL1

6.22e-0929164int:ZNF517
InteractionZNF408 interactions

LRP2 LTBP4 LRP1B HSPG2 SORL1

7.37e-08145165int:ZNF408
InteractionZNF563 interactions

LTBP4 LRP1B SORL1

8.99e-0812163int:ZNF563
InteractionZFP41 interactions

LRP2 LTBP4 LRP1B SORL1

1.02e-0757164int:ZFP41
InteractionZNF224 interactions

LRP2 LRP1B SORL1

4.64e-0720163int:ZNF224
InteractionEGFL6 interactions

LRP2 LRP1B SORL1

5.41e-0721163int:EGFL6
InteractionFEZF1 interactions

LRP2 LRP1B SORL1

1.33e-0628163int:FEZF1
InteractionCFC1 interactions

LTBP4 THBS1 ADAM19 SORL1

2.50e-06126164int:CFC1
InteractionFOXD4L6 interactions

LTBP4 LRP1B SORL1

7.40e-0649163int:FOXD4L6
InteractionDKK2 interactions

LRP2 LRP1B SORL1

7.40e-0649163int:DKK2
InteractionZNF169 interactions

LTBP4 LRP1B SORL1

9.94e-0654163int:ZNF169
InteractionLRPAP1 interactions

LRP2 LRP1B LRP8 SORL1

1.03e-05180164int:LRPAP1
InteractionFBXO2 interactions

LRP2 LTBP4 LRP1B HSPG2 SORL1

1.25e-05411165int:FBXO2
InteractionANKRD36B interactions

LRP2 LRP1B SORL1

1.37e-0560163int:ANKRD36B
InteractionZNF331 interactions

LTBP4 LRP1B SORL1

1.58e-0563163int:ZNF331
InteractionHRG interactions

LTBP4 LRP1B THBS1

1.58e-0563163int:HRG
InteractionGPC5 interactions

HSPG2 GPC5

2.12e-059162int:GPC5
InteractionIGFL3 interactions

LRP2 LRP1B SORL1

2.68e-0575163int:IGFL3
InteractionTAFA3 interactions

LRP2 LRP1B SORL1

3.01e-0578163int:TAFA3
InteractionPI15 interactions

HSPG2 THBS1 SORL1

3.63e-0583163int:PI15
InteractionSIRPD interactions

HSPG2 THBS1 SORL1

4.04e-0586163int:SIRPD
InteractionTIMP3 interactions

LRP2 LRP1B SORL1

4.62e-0590163int:TIMP3
InteractionMDK interactions

LRP2 LRP8 SORL1

4.78e-0591163int:MDK
InteractionRSPO1 interactions

LRP1B SORL1

6.17e-0515162int:RSPO1
InteractionPRG2 interactions

LTBP4 HSPG2 THBS1 SORL1

6.23e-05285164int:PRG2
InteractionSCN3A interactions

LRP2 LRP8

7.05e-0516162int:SCN3A
InteractionDEFB123 interactions

LRP1B SORL1

7.05e-0516162int:DEFB123
InteractionGLI4 interactions

LRP2 LRP1B SORL1

1.23e-04125163int:GLI4
InteractionTNFAIP6 interactions

LRP2 THBS1

2.05e-0427162int:TNFAIP6
InteractionLRP2 interactions

LRP2 LRP1B THBS1

2.28e-04154163int:LRP2
InteractionAPOH interactions

LRP2 LRP8

2.54e-0430162int:APOH
InteractionITGB1BP1 interactions

LRP2 LRP8

3.08e-0433162int:ITGB1BP1
InteractionAPOE interactions

LRP2 LRP8 SORL1

3.10e-04171163int:APOE
InteractionZNF74 interactions

LTBP4 SORL1

3.27e-0434162int:ZNF74
InteractionSOST interactions

LRP2 SORL1

3.46e-0435162int:SOST
InteractionNDP interactions

LRP1B SORL1

3.46e-0435162int:NDP
InteractionGREM2 interactions

LRP2 SORL1

3.87e-0437162int:GREM2
InteractionATN1 interactions

LRP2 LTBP4 HSPG2

4.03e-04187163int:ATN1
InteractionEMX2 interactions

LRP2 PAXX

4.30e-0439162int:EMX2
InteractionCCN2 interactions

LRP2 HSPG2

4.53e-0440162int:CCN2
InteractionZNF264 interactions

LRP2 SORL1

4.76e-0441162int:ZNF264
InteractionAPBA2 interactions

LRP2 LRP8

6.53e-0448162int:APBA2
InteractionPATE1 interactions

LRP1B SORL1

6.80e-0449162int:PATE1
InteractionDYRK1A interactions

LRP2 LRP1B THBS1 ADAM19

7.79e-04552164int:DYRK1A
InteractionTYW3 interactions

DDHD1 SORL1

7.95e-0453162int:TYW3
InteractionSERPINE1 interactions

LRP2 LRP1B

8.26e-0454162int:SERPINE1
InteractionTAFA4 interactions

LRP2 SORL1

8.56e-0455162int:TAFA4
InteractionFGF2 interactions

HSPG2 THBS1

8.56e-0455162int:FGF2
InteractionCLU interactions

LRP2 LRP1B LRP8

8.84e-04245163int:CLU
InteractionMAPK8IP1 interactions

LRP2 LRP8

9.52e-0458162int:MAPK8IP1
InteractionSPARC interactions

HSPG2 THBS1

1.19e-0365162int:SPARC
InteractionANAPC10 interactions

LRP2 LRP8

1.31e-0368162int:ANAPC10
InteractionZNF8 interactions

LTBP4 LRP1B

1.38e-0370162int:ZNF8
InteractionCOBLL1 interactions

THBS1 DDHD1

1.63e-0376162int:COBLL1
InteractionZNF707 interactions

LTBP4 SORL1

1.76e-0379162int:ZNF707
InteractionSNX17 interactions

LRP2 LRP8

1.85e-0381162int:SNX17
InteractionSDF2L1 interactions

HSPG2 ADAM19 SORL1

1.94e-03322163int:SDF2L1
InteractionLRP1B interactions

LRP2 LRP1B

2.03e-0385162int:LRP1B
InteractionLGALS1 interactions

LRP2 THBS1 SORL1

2.12e-03332163int:LGALS1
InteractionPDGFB interactions

HSPG2 THBS1

2.17e-0388162int:PDGFB
InteractionRLN1 interactions

LRP1B SORL1

2.42e-0393162int:RLN1
InteractionCTSG interactions

THBS1 SORL1

2.53e-0395162int:CTSG
InteractionFGA interactions

LRP1B THBS1

2.53e-0395162int:FGA
InteractionCOL18A1 interactions

HSPG2 THBS1

2.69e-0398162int:COL18A1
InteractionHSPG2 interactions

HSPG2 GPC5

2.69e-0398162int:HSPG2
InteractionTTR interactions

LRP2 HSPG2

2.80e-03100162int:TTR
InteractionSYT1 interactions

LRP2 LRP1B

3.08e-03105162int:SYT1
InteractionFGG interactions

LRP1B THBS1

3.08e-03105162int:FGG
InteractionDAB1 interactions

LRP2 LRP8

3.19e-03107162int:DAB1
InteractionEDN3 interactions

HSPG2 SORL1

3.25e-03108162int:EDN3
InteractionNOS1AP interactions

LRP2 LRP8

3.55e-03113162int:NOS1AP
InteractionMAPK8IP2 interactions

LRP2 LRP8

3.68e-03115162int:MAPK8IP2
InteractionLYZL1 interactions

THBS1 SORL1

3.87e-03118162int:LYZL1
InteractionGIPC1 interactions

LRP2 LRP8

3.93e-03119162int:GIPC1
InteractionSULF2 interactions

LRP2 LRP1B

3.93e-03119162int:SULF2
InteractionCACNA1A interactions

LTBP4 HSPG2

4.19e-03123162int:CACNA1A
InteractionZDHHC15 interactions

LRP2 THBS1

4.33e-03125162int:ZDHHC15
InteractionINSIG1 interactions

HSPG2 THBS1

4.46e-03127162int:INSIG1
InteractionTHBS1 interactions

LRP2 THBS1

4.46e-03127162int:THBS1
InteractionZSCAN21 interactions

LRP1B SORL1

4.53e-03128162int:ZSCAN21
InteractionFBLN1 interactions

LTBP4 HSPG2

4.60e-03129162int:FBLN1
InteractionSYNJ2BP interactions

LRP2 LRP8

4.74e-03131162int:SYNJ2BP
InteractionSCGB1D1 interactions

LRP1B SORL1

4.88e-03133162int:SCGB1D1
InteractionGFI1B interactions

LTBP4 HSPG2

5.10e-03136162int:GFI1B
InteractionMFAP4 interactions

THBS1 ADAM19

5.32e-03139162int:MFAP4
InteractionDAB2 interactions

LRP2 LRP8

5.39e-03140162int:DAB2
InteractionCFH interactions

THBS1 LRP8

5.39e-03140162int:CFH
InteractionCST1 interactions

LTBP4 HSPG2

5.47e-03141162int:CST1
InteractionKLK15 interactions

THBS1 ADAM19

6.25e-03151162int:KLK15
CytobandEnsembl 112 genes in cytogenetic band chr9q34

VAV2 PAXX HMCN2

2.22e-04325173chr9q34
GeneFamilyLow density lipoprotein receptors

LRP2 LRP1B LRP8

6.36e-0813123634
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

HSPG2 HMCN2

4.91e-03161122593
GeneFamilyImmunoglobulin like domain containing

HSPG2 HMCN2

6.97e-03193122594
CoexpressionNABA_MATRISOME

LTBP4 HSPG2 THBS1 GPC5 ADAM19 HMCN2 SCUBE2

1.69e-061008177MM17056
CoexpressionNABA_MATRISOME

LTBP4 HSPG2 THBS1 GPC5 ADAM19 HMCN2 SCUBE2

1.90e-061026177M5889
CoexpressionFOURNIER_ACINAR_DEVELOPMENT_EARLY_DN

THBS1 LRP8

5.93e-066172M14136
CoexpressionGSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_DN

GPR162 DDHD1 ADAM19 SORL1

7.10e-06199174M8070
CoexpressionAMIT_EGF_RESPONSE_240_HELA

THBS1 VAV2 LRP8

7.20e-0659173M7714
CoexpressionNABA_CORE_MATRISOME

LTBP4 HSPG2 THBS1 HMCN2

2.36e-05270174MM17057
CoexpressionNABA_CORE_MATRISOME

LTBP4 HSPG2 THBS1 HMCN2

2.53e-05275174M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

LTBP4 THBS1 HMCN2

2.40e-04191173MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

LTBP4 THBS1 HMCN2

2.59e-04196173M3008
CoexpressionGSE36826_NORMAL_VS_STAPH_AUREUS_INF_SKIN_UP

THBS1 LRP8 SORL1

2.67e-04198173M9534
CoexpressionGSE36826_NORMAL_VS_STAPH_AUREUS_INF_IL1R_KO_SKIN_DN

THBS1 LRP8 SORL1

2.71e-04199173M9532
CoexpressionGSE19923_WT_VS_HEB_KO_DP_THYMOCYTE_UP

GPR162 LTBP4 ADAM19

2.75e-04200173M7279
CoexpressionAtlasStromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3

LTBP4 HSPG2 THBS1

6.00e-0597173GSM777043_100
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000

LRP2 LTBP4 THBS1 GPC5 LRP8 SCUBE2

7.42e-05976176Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000
ToppCellLA|World / Chamber and Cluster_Paper

LRP2 LRP1B ADAM19 HMCN2

7.48e-07193174d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellTracheal-10x5prime-Stromal-Chondrocytic-Chondrocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1B CORIN GPC5 SCUBE2

8.28e-0719817455f013e9e6587d9ece59751fa131b1d22d6cceea
ToppCellTracheal-10x5prime-Stromal-Chondrocytic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1B CORIN GPC5 SCUBE2

8.28e-07198174c72ef2ddcbb6dacbed4c6200d89e17d57314dcdc
ToppCellTracheal-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1B CORIN GPC5 SCUBE2

8.62e-07200174b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCellTracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1B CORIN GPC5 SCUBE2

8.62e-07200174f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCellIonocyte|World / shred by cell class for nasal brushing

CORIN THBS1 SCUBE2

2.58e-051541736b78fb0c96fc7b5e901c39b3424f4aa8d0a6b9cf
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR162 ADAM19 LRP8

2.73e-05157173fc127e7720649e746f3d3f5c2e9e63784767106a
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR162 ADAM19 LRP8

2.73e-0515717366a191cef4aa00811bb04462310d012610006f85
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 LRP8 SCUBE2

2.79e-05158173a2efcc184ef13d81373e3690253ba35f6be09c5f
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 LRP8 SCUBE2

2.79e-05158173ba9998cbf786c515d30fe42de02c7a246db1b6f9
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 LRP8 SCUBE2

2.79e-05158173e52eff2bd1e7e0ce9c278ed5109802865e0fe69c
ToppCellNS-control-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

THBS1 VAV2 SCUBE2

3.23e-051661736d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCelldroplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR162 ADAM19 LRP8

3.23e-051661731ca888ae8168707493f19ee52a89d7c70e6cb51d
ToppCelldroplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR162 ADAM19 LRP8

3.23e-051661734cba4ca1aa2321b9ef7cd230932b890d2434a252
ToppCelldroplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR162 VAV2 LRP8

3.59e-0517217324ecfda5e43e28f190089770cd2eae5bf2ed292b
ToppCelldroplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR162 VAV2 LRP8

3.59e-05172173db5a31cafce4346fe459d7f35210823fd7004439
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_macrophage-macrophage|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LTBP4 THBS1 SCUBE2

3.71e-051741732479e4804253f55647d2192e40566d713419c51b
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_macrophage|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LTBP4 THBS1 SCUBE2

3.71e-051741737f1e26b58b66f4ac4c3bc315354bd620ad782eaa
ToppCellfacs-Skin-Anagen-24m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR162 LTBP4 HSPG2

3.78e-051751735552ff1e13f931c8cd7780726c90b5609497a648
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LTBP4 HSPG2 HMCN2

3.84e-0517617352af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCellCOVID-19-Epithelial-Ionocytes|Epithelial / Condition, Lineage and Cell class

THBS1 SORL1 SCUBE2

4.18e-051811734a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-1|TCGA-Thryoid / Sample_Type by Project: Shred V9

CORIN THBS1 ADAM19

4.32e-0518317306e4b05d86a7d643569e19575c2c9aa351d33f29
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

4.32e-05183173c7ef8ee2b3fcfa69cea0fdcb2041674b832933db
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

4.32e-05183173c9d9d7dd629ce6787502103b158a07e8684a66f8
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

4.32e-0518317392eee4bdd84965ae0bd1ed1c7f26a3b83ad0cdac
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VAV2 GPC5 LRP8

4.46e-05185173f4ac62009c0ad3346e71b809e17727303c4df153
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1B HSPG2 LRP8

4.53e-0518617392092f11ecce22c14f244e42c499af0822977e6f
ToppCell(2)_Fibroblasts-(20)_Fibro-1|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

LTBP4 ADAM19 HMCN2

4.53e-05186173e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCellfacs-Lung-EPCAM-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 SORL1 SCUBE2

4.53e-051861737c4eb769574f9f32753cea1cc38c711dabba88b9
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

HSPG2 HMCN2 SCUBE2

4.53e-05186173a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LTBP4 HSPG2 THBS1

4.68e-05188173b382d18fb09fb2869f3c151efa71540a7f5ed229
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LRP2 GPC5 SORL1

4.75e-051891737659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCelldroplet-Pancreas-Endocrine-21m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

4.75e-0518917337ce47abd6f96df04d35a4a6189d007bef5ccc94
ToppCelldroplet-Pancreas-Endocrine-21m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

4.75e-05189173b55324cb365a827d071952709bbf0e8ef8c313de
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LTBP4 THBS1 SCUBE2

4.75e-05189173e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LTBP4 THBS1 SCUBE2

4.75e-051891732a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCelldroplet-Pancreas-Endocrine-21m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

4.75e-0518917362e46d59d3b89d4566b595c704d8b02f1ea9060b
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

4.83e-051901739d5242759546be0089981ef1877e4ed5f81face5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CORIN THBS1 ADAM19

4.83e-05190173f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CORIN THBS1 ADAM19

4.83e-05190173562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LTBP4 THBS1 SCUBE2

4.83e-05190173d60395739458d7f47a3350ade751fe3819500320
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LTBP4 THBS1 SCUBE2

4.90e-051911735c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LTBP4 THBS1 SCUBE2

4.90e-05191173b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LTBP4 THBS1 SCUBE2

4.90e-0519117380484d39f34703a33b9bac09826b7a526e883cab
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

4.98e-05192173bcd8876235be503186f119653b39476488c0fa15
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

4.98e-05192173f4cd65e6c5b17bcabf45fe5b687246c72e7975f7
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

4.98e-05192173ac1477433704573f95111eee6263b93668d2845e
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LTBP4 THBS1 SCUBE2

4.98e-05192173ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LTBP4 HSPG2 HMCN2

4.98e-05192173cdc652dbfabe41b324fd85c1ed933d29fb73a49f
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

4.98e-051921738937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LTBP4 HSPG2 HMCN2

4.98e-0519217329bee88b45e23f16543ffc7cc361bc5da5d16a2b
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LTBP4 HMCN2 SCUBE2

4.98e-0519217320ede290e01ad574afd122d72b59dbc52c595fad
ToppCellControl-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

LTBP4 LRP1B HSPG2

4.98e-051921737e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

4.98e-05192173e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LTBP4 THBS1 SCUBE2

4.98e-05192173df1545670370fb1010c567cd059c2783eab315f7
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

5.06e-051931735d42979d811ee13a07dee08a3743a90776017cb4
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

5.06e-0519317395e64b9580d30c28702639a043a8b72ce1cadeb6
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VAV2 LRP8 SCUBE2

5.06e-051931738b77625bf3c87d39767fb391d1beaca4ab02342b
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

5.06e-0519317397c0730aad9135ac681250b3871cc094a28f80a7
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VAV2 LRP8 SCUBE2

5.06e-051931732c15186d15545804cc262da9137ab825609d4b2c
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAXX ADAM19 SORL1

5.06e-0519317300349d176fb6a46cbcc99c41d975651b6e9aaad4
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LTBP4 HSPG2 HMCN2

5.06e-05193173cc355b2ed6510619cad969ae074126d7c8db784d
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

LTBP4 THBS1 HMCN2

5.13e-05194173d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LTBP4 CORIN THBS1

5.13e-051941737bf6edefd13047e04665dbe34051ef3f481f85a4
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LTBP4 CORIN THBS1

5.13e-0519417319e5beae2c1f8bf42cbe618e89810ce7b01a396c
ToppCellMesenchymal_cells-Arteriolar_fibro.|World / Lineage and Cell class

LTBP4 HSPG2 HMCN2

5.13e-05194173c1e8923a50b4138a1e4c054c0c17b7f7122aa8a9
ToppCellMesenchymal_cells-Stromal_fibro.|World / Lineage and Cell class

LTBP4 HSPG2 THBS1

5.21e-0519517369723b06c2a5c2aaf4d10874b11bca7f06822bdc
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAXX ADAM19 SORL1

5.21e-0519517336c784709ee32174e05b457500339c3b8eee3244
ToppCellCOVID-19-Heart-Low_count_Fib|COVID-19 / Disease (COVID-19 only), tissue and cell type

LTBP4 HSPG2 THBS1

5.21e-05195173e09590d1f51d5fa57fceb84c9f48f84b23d4d224
ToppCellfacs-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LTBP4 HSPG2 THBS1

5.21e-05195173c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCelldistal-Hematologic-EREG+_Dendritic-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

THBS1 ADAM19 SORL1

5.29e-05196173c17bb7b3992bfec194bfa310f201a5c64b35868e
ToppCelldistal-Hematologic-EREG+_Dendritic|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

THBS1 ADAM19 SORL1

5.29e-0519617314c6870d125fc2bdacf4199883399cec0dd3f569
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

5.29e-05196173b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LTBP4 HSPG2 HMCN2

5.29e-05196173a20a56d8997d6db2a10046c8801c619a379de83c
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 HSPG2 THBS1

5.29e-05196173787c6cd92035e0b1108c2c086c42a229016e476b
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THBS1 ADAM19 HMCN2

5.37e-051971733332b9b5bf78f0203ebbd94257a36e9054d896c3
ToppCelldistal-2-Hematologic-Classical_Monocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

THBS1 ADAM19 SORL1

5.37e-051971739a1c9221904ad1e46e64e3785516804e87128adc
ToppCelldistal-2-Hematologic-EREG+_Dendritic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

THBS1 ADAM19 SORL1

5.37e-051971736fcca7c071e35786b715adeb18be317d34315d7e
ToppCellMesenchymal_cells-Arteriolar_fibro.|Mesenchymal_cells / Lineage and Cell class

LTBP4 HSPG2 HMCN2

5.37e-05197173cb321836980e7b4efbb9284c6af7ccd34079d2be
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LTBP4 THBS1 SCUBE2

5.54e-0519917338ed3bc7daa993d9edcf3e7834597ebb06dd24f8
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LTBP4 THBS1 SCUBE2

5.62e-052001739b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellKidney|World / Skin and Kidney Cells in Lupus Nephritis Patients.

LRP2 THBS1 SORL1

5.62e-052001731f99afa1f3c32a2a9cfb4ad33ff4d404e34fac63
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

LTBP4 THBS1 SCUBE2

5.62e-05200173a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LTBP4 HSPG2 HMCN2

5.62e-0520017393e13937ec74418a697c37d56f57509fb2154780
ToppCell390C-Epithelial_cells-Epithelial-A_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ADAM19 HMCN2

6.25e-0498172cb0941481aef9068d7dbce0d1b6cf125f482a98d
ToppCell390C-Epithelial_cells-Epithelial-A_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ADAM19 HMCN2

6.25e-0498172a74fb790c135bd0d0033df3aca7b789d8b25e361
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

VAV2 GPC5

8.59e-04115172ac73aa06e617ed791c6ae9e38189bac74188c27b
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-4|TCGA-Cervix / Sample_Type by Project: Shred V9

GPR162 SCUBE2

1.06e-031281723ca9ae69fb8cb7f8acb7540aa71778bc917da4df
ToppCellAT2_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 SCUBE2

1.11e-03131172ff4e618bd944f852bbd34438f740187aca82460f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

THBS1 ADAM19

1.13e-03132172a1fda8c5287168c4f159203ed27cadfb4ce1b131
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP2 LRP1B

1.25e-03139172a1945b07f177cde40e7eea03a19236ce76165857
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 HMCN2

1.25e-03139172b07929348ec9ad95d7bce33a7deac0938227b19f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CORIN HMCN2

1.27e-031401722c44e8cc5190226049be7ebc465d685393e701c4
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HSPG2 THBS1

1.30e-03142172f4e4cde228149d5a536fbf0517ed71d81e296faf
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GPC5 LRP8

1.30e-031421725b6b0c611c83b23ef7289854a515b78f6cf84500
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B VAV2

1.34e-031441725665dd2839b6c8ddbf5ddb2d22e1ee6073f74c3b
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP2 THBS1

1.34e-031441721b9e95e4f6e40042d3cf2f94c067f3a6b19428ea
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THBS1 SORL1

1.34e-03144172c0c5f254a960ba5e5f1354599d54e77360e6c2ac
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THBS1 SORL1

1.34e-031441721efa434e577d1f87e02df01667782f414d63bd60
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-cDC2-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

THBS1 ADAM19

1.40e-03147172c5913cc351577e54536dd239a33e5f7a5cb79672
ComputationalGenes in the cancer module 236.

LRP8 SORL1

1.73e-0418122MODULE_236
DrugNitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A

LRP2 GPR162 LTBP4 THBS1 VAV2

2.62e-071971756043_UP
Drugmonatepil

LRP2 LRP1B SORL1

1.25e-0629173CID000060810
DrugEpi Lovastatin

LRP2 LRP1B THBS1 LRP8 SORL1

3.91e-06341175CID000003962
DrugAC1L1J6H

LRP2 LRP1B VAV2 SORL1

2.41e-05236174CID000004889
Drugepicholesterol

LRP2 LRP1B HSPG2 LRP8 SORL1

7.84e-05636175CID000000304
Drugpitavastatin

LRP2 LRP1B SORL1

7.90e-05114173CID005282451
Drug1-anilino-4-methyl-2-methylthio-4-phenylimidazolin-5-one

LRP2 HSPG2 THBS1 SORL1

1.42e-04373174ctd:C540355
Drugezetimibe

LRP2 LRP1B SORL1

1.68e-04147173CID000150311
Drugsimvastatin

LRP2 LRP1B THBS1 SORL1

1.69e-04390174CID000054454
Drugsodium cholate

LRP2 LRP1B THBS1 SORL1

2.01e-04408174CID000000303
Drug25-hydroxycholesterol

LRP2 LRP1B SORL1

2.15e-04160173CID000065094
Drugprobucol

LRP2 LRP1B SORL1

2.23e-04162173CID000004912
Drugpyrachlostrobin

LRP2 HSPG2 THBS1 GPC5 SORL1

2.45e-04811175ctd:C513428
Drugvitamin E

LRP2 LRP1B LRP8 SORL1

2.71e-04441174CID000002116
DrugWithaferin A [5119-48-2]; Down 200; 1uM; PC3; HT_HG-U133A

HSPG2 THBS1 SORL1

3.00e-041791734554_DN
Drugthapsigargin; Down 200; 0.1uM; PC3; HT_HG-U133A

HSPG2 ADAM19 SORL1

3.00e-041791737103_DN
DrugICI 182,780; Down 200; 0.01uM; MCF7; HT_HG-U133A

LTBP4 THBS1 LRP8

3.15e-041821731663_DN
Drugtrifluoperazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A

LRP2 LTBP4 VAV2

3.74e-041931735584_DN
DrugAC1OAGKW

LRP2 THBS1 LRP8

3.74e-04193173CID006857413
DrugIopanoic acid [96-83-3]; Down 200; 7uM; MCF7; HT_HG-U133A

LRP2 LTBP4 ADAM19

3.79e-041941735448_DN
DrugMefexamide hydrochloride [3413-64-7]; Down 200; 12.6uM; MCF7; HT_HG-U133A

LTBP4 THBS1 VAV2

3.79e-041941732284_DN
DrugHydrocortisone base [50-23-7]; Up 200; 11uM; MCF7; HT_HG-U133A

THBS1 VAV2 ADAM19

3.79e-041941733284_UP
DrugReserpinic acid hydrochloride; Up 200; 9.2uM; MCF7; HT_HG-U133A

VAV2 ADAM19 SCUBE2

3.85e-041951737323_UP
DrugDyclonine hydrochloride [536-43-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A

HSPG2 THBS1 LRP8

3.85e-041951737022_UP
DrugProgesterone [57-83-0]; Up 200; 12.8uM; HL60; HT_HG-U133A

THBS1 VAV2 SCUBE2

3.85e-041951732426_UP
Drug2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A

LTBP4 HSPG2 SCUBE2

3.85e-041951731639_DN
DrugAH23848 hemicalcium salt hydrate; Down 200; 1uM; MCF7; HT_HG-U133A

LTBP4 THBS1 VAV2

3.85e-041951736890_DN
DrugProtriptyline hydrochloride [1225-55-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A

THBS1 VAV2 SCUBE2

3.91e-041961735438_DN
DrugCinoxacin [28657-80-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A

LTBP4 THBS1 ADAM19

3.97e-041971733463_UP
DrugAmpyrone [83-07-8]; Up 200; 19.6uM; PC3; HT_HG-U133A

LRP2 HSPG2 VAV2

3.97e-041971734507_UP
DrugTrimethadione [127-48-0]; Up 200; 28uM; MCF7; HT_HG-U133A

LTBP4 THBS1 ADAM19

3.97e-041971734165_UP
DrugDoxazosin mesylate [77883-43-3]; Down 200; 7.4uM; MCF7; HT_HG-U133A

LTBP4 THBS1 VAV2

3.97e-041971733363_DN
DrugTamoxifen citrate [54965-24-1]; Down 200; 7uM; MCF7; HT_HG-U133A

LRP2 LTBP4 THBS1

3.97e-041971732212_DN
DrugSulfameter [651-06-9]; Up 200; 14.2uM; HL60; HT_HG-U133A

VAV2 ADAM19 SCUBE2

3.97e-041971732712_UP
DrugAtropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; MCF7; HT_HG-U133A

LRP2 LTBP4 VAV2

3.97e-041971732761_UP
DrugClomipramine hydrochloride [17321-77-6]; Down 200; 11.4uM; MCF7; HT_HG-U133A

LTBP4 VAV2 SCUBE2

3.97e-041971733182_DN
DrugMeclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A

LTBP4 LRP1B ADAM19

3.97e-041971734729_UP
DrugAjmalicine hydrochloride [4373-34-6]; Down 200; 10.2uM; MCF7; HT_HG-U133A

LRP2 LTBP4 ADAM19

3.97e-041971735459_DN
DrugDisulfiram [97-77-8]; Down 200; 13.4uM; PC3; HT_HG-U133A

LRP2 HSPG2 THBS1

4.03e-041981735729_DN
DrugSpiramycin [8025-81-8]; Up 200; 4.8uM; MCF7; HT_HG-U133A

LRP2 LTBP4 THBS1

4.03e-041981733419_UP
DrugBephenium hydroxynaphthoate [3818-50-6]; Up 200; 9uM; MCF7; HT_HG-U133A

GPR162 LRP1B GPC5

4.03e-041981735628_UP
DrugAtropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

LRP2 HSPG2 THBS1

4.03e-041981736812_UP
DrugCyclacillin [3485-14-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

LRP2 LTBP4 THBS1

4.03e-041981734358_UP
DrugCefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; MCF7; HT_HG-U133A

HSPG2 THBS1 ADAM19

4.03e-041981733581_DN
DrugOxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; HL60; HT_HG-U133A

THBS1 ADAM19 SCUBE2

4.03e-041981736145_UP
DrugAdrenosterone [382-45-6]; Up 200; 13.4uM; HL60; HT_HG-U133A

HSPG2 THBS1 SCUBE2

4.03e-041981733107_UP
DrugKarakoline [39089-30-0]; Up 200; 10.6uM; HL60; HT_HG-U133A

THBS1 VAV2 ADAM19

4.09e-041991732203_UP
DrugKhellin [82-02-0]; Up 200; 15.4uM; PC3; HT_HG-U133A

LTBP4 HSPG2 VAV2

4.09e-041991736641_UP
DrugN-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; PC3; HT_HG-U133A

GPR162 LTBP4 HSPG2

4.09e-041991734311_UP
DrugEpiandrosterone [481-29-8]; Up 200; 13.8uM; MCF7; HT_HG-U133A

LRP2 THBS1 ADAM19

4.09e-041991733306_UP
DrugChlorzoxazone [95-25-0]; Up 200; 23.6uM; MCF7; HT_HG-U133A

LTBP4 VAV2 SCUBE2

4.15e-042001737456_UP
DrugOxantel pamoate [68813-55-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A

GPR162 HSPG2 VAV2

4.15e-042001732632_UP
DrugMyricetin [529-44-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A

LRP2 THBS1 ADAM19

4.15e-042001734170_UP
DrugFR139317

HSPG2 GPC5

4.65e-0443172CID000107810
DrugProxyl-opc

GPR162 LRP8

4.87e-0444172CID000124490
Diseasecolorectal cancer, overall survival

ADAM19 SORL1

9.72e-0529152EFO_0000638, MONDO_0005575
Diseasepack-years measurement, systolic blood pressure

LRP2 LRP1B

1.34e-0434152EFO_0006335, EFO_0006526
DiseaseFEV/FEC ratio

LTBP4 HSPG2 GPC5 ADAM19 SORL1

2.62e-041228155EFO_0004713
Diseasefunctional brain measurement

HSPG2 THBS1

7.82e-0482152EFO_0007849
Diseasecarotid artery intima media thickness

LTBP4 LRP1B GPC5

1.40e-03450153EFO_0007117
Diseasenon-alcoholic fatty liver disease, type 2 diabetes mellitus

VAV2 GPC5

1.40e-03110152EFO_0003095, MONDO_0005148
Diseasepeak expiratory flow

LTBP4 ADAM19 SORL1

1.87e-03498153EFO_0009718
DiseaseAlzheimer's disease (is_implicated_in)

LRP8 SORL1

2.01e-03132152DOID:10652 (is_implicated_in)
Diseaseinsomnia, total blood protein measurement

DDHD1 SCUBE2

2.51e-03148152EFO_0004536, EFO_0004698
Diseaseneuroticism measurement, cognitive function measurement

LRP1B LRP8 SCUBE2

2.69e-03566153EFO_0007660, EFO_0008354
DiseaseCraniofacial Abnormalities

LRP2 HSPG2

2.79e-03156152C0376634
DiseaseParoxysmal atrial fibrillation

HSPG2 SORL1

2.79e-03156152C0235480
DiseasePersistent atrial fibrillation

HSPG2 SORL1

2.79e-03156152C2585653
Diseasefamilial atrial fibrillation

HSPG2 SORL1

2.79e-03156152C3468561
Diseasevital capacity

LRP2 LTBP4 HSPG2 THBS1

2.89e-031236154EFO_0004312
DiseaseAtrial Fibrillation

HSPG2 SORL1

2.93e-03160152C0004238
Diseasebrain volume measurement

LTBP4 THBS1 LRP8

3.10e-03595153EFO_0006930
DiseaseCOVID-19, mortality

LRP2 LRP1B

3.30e-03170152EFO_0004352, MONDO_0100096
Diseaseattempted suicide

LRP2 SCUBE2

3.61e-03178152EFO_0004321
Diseasemacula measurement

LRP2 SORL1

4.06e-03189152EFO_0008375
Diseasechronic obstructive pulmonary disease

LTBP4 ADAM19 SCUBE2

4.66e-03688153EFO_0000341
Diseaseoptic disc size measurement

LRP2 LRP1B

4.75e-03205152EFO_0004832
DiseaseColorectal Carcinoma

LRP2 ADAM19 SORL1

4.93e-03702153C0009402
Diseaseceramide measurement

CORIN ADAM19

6.19e-03235152EFO_0010222

Protein segments in the cluster

PeptideGeneStartEntry
NGYLEDGEECDCGEE

ADAM19

421

Q9H013
DYLCDGQEDCEDGSD

HSPG2

301

P98160
VCYCEGEESGEGDRG

PAXX

21

Q9BUH6
GDFDCADGSDERNCE

LRP1B

3536

Q9NZR2
DDDGGCDDYAEGRVC

GPR162

351

Q16538
VEQVSGDCDDEDGCG

GPC5

491

P78333
ADGAGCEDVDECLEG

HMCN2

4706

Q8NDA2
VCDGDVDCTDGYDEN

LRP2

2971

P98164
EVCNGVDDCGDGTDE

LRP2

3901

P98164
DGYDDCGDLSDEQNC

CORIN

326

Q9Y5Q5
GTCDDVDECQEYGPE

LTBP4

1001

Q8N2S1
GEDDDEDRACGFCQS

DDHD1

226

Q8NEL9
GYQGEGRQCEDIDEC

SCUBE2

76

Q9NQ36
AAVFVCDGDDDCGDG

LRP8

181

Q14114
GMDDCGDYSDEANCE

SORL1

1346

Q92673
QEDYDKDGIGDACDD

THBS1

726

P07996
DYLEEMEACEDGGCQ

TMEM247

51

A6NEH6
EDIYDCVPCEDGGDD

VAV2

156

P52735