Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	GATA3 WT1 MAFB RFX6 HIVEP2 HOXC11	1.92e-04	560	31	6	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	GATA3 WT1 MAFB RFX6 HIVEP2 HOXC11	2.03e-04	566	31	6	GO:0001216
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	GATA3 WT1 MAFB RFX6 HIVEP2 HOXC11 ZNF550 NFX1	1.11e-03	1412	31	8	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	GATA3 WT1 MAFB RFX6 HIVEP2 HOXC11 ZNF550 NFX1	1.38e-03	1459	31	8	GO:0000977
GeneOntologyMolecularFunction	protease binding	MALT1 MBP SERPINE1	2.73e-03	181	31	3	GO:0002020
MousePheno	inner ear cyst	GATA3 MAFB	3.32e-05	5	26	2	MP:0006287
MousePheno	abnormal urinary system development	GATA3 WT1 ADAMTS18 MAFB	4.92e-05	111	26	4	MP:0003942
MousePheno	podocyte microvillus transformation	WT1 MAFB	6.95e-05	7	26	2	MP:0011868
MousePheno	increased urine protein level	WT1 MAFB ALMS1 SERPINE1	1.54e-04	149	26	4	MP:0002962
Pathway	REACTOME_KIDNEY_DEVELOPMENT	GATA3 WT1 HOXC11	9.00e-05	46	27	3	M48243
Pubmed	Higher-Order Kidney Organogenesis from Pluripotent Stem Cells.	GATA3 WT1 MAFB	2.01e-07	13	32	3	29129523
Pubmed	Combination of MUC5ac and WT-1 immunohistochemistry is useful in distinguishing pancreatic ductal carcinoma from ovarian serous carcinoma in effusion cytology.	WT1 MUC5AC	8.20e-07	2	32	2	19856421
Pubmed	Dependence of nodal sodium channel clustering on paranodal axoglial contact in the developing CNS.	CNTNAP1 MBP	8.20e-07	2	32	2	10460258
Pubmed	Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning.	GATA3 WT1 MAFB	1.08e-06	22	32	3	29449451
Pubmed	Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway.	LATS2 PATJ USP9X	1.81e-06	26	32	3	28720576
Pubmed	Gata3 cooperates with Gcm2 and MafB to activate parathyroid hormone gene expression by interacting with SP1.	GATA3 MAFB	2.46e-06	3	32	2	25917456
Pubmed	Genetic Polymorphisms of GP1BA, PEAR1, and PAI-1 may be Associated with Serum sIgE and Blood Eosinophil Levels in Chinese Patients with Allergic Diseases.	PEAR1 SERPINE1	2.46e-06	3	32	2	38299390
Pubmed	Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.	GATA3 MUC5AC	2.46e-06	3	32	2	30552067
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	HELZ CPD LATS2 ALMS1 NFX1	4.06e-06	263	32	5	34702444
Pubmed	Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition.	LATS2 USP9X	4.92e-06	4	32	2	26598551
Pubmed	CrkRS: a novel conserved Cdc2-related protein kinase that colocalises with SC35 speckles.	POLR2A MBP	4.92e-06	4	32	2	11683387
Pubmed	Integration of Cistromic and Transcriptomic Analyses Identifies Nphs2, Mafb, and Magi2 as Wilms' Tumor 1 Target Genes in Podocyte Differentiation and Maintenance.	WT1 MAFB	4.92e-06	4	32	2	25556170
Pubmed	Citron kinase interacts with LATS2 and inhibits its activity by occluding its hydrophobic phosphorylation motif.	LATS2 PATJ USP9X	6.83e-06	40	32	3	30865227
Pubmed	Regulation of T cell function by the ubiquitin-specific protease USP9X via modulating the Carma1-Bcl10-Malt1 complex.	MALT1 USP9X	8.19e-06	5	32	2	23690623
Pubmed	Ermin, a myelinating oligodendrocyte-specific protein that regulates cell morphology.	CNTNAP1 MBP	8.19e-06	5	32	2	16421295
Pubmed	An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation.	ZNF488 MBP	8.19e-06	5	32	2	16908628
Pubmed	Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development.	WT1 LATS2	1.23e-05	6	32	2	29689192
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	GATA3 WT1 MAFB HIVEP2 HOXC11 POLR2A NFX1	1.23e-05	877	32	7	20211142
Pubmed	SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.	HELZ POLR2A	1.72e-05	7	32	2	15235609
Pubmed	A Novel Role for GATA3 in Mesangial Cells in Glomerular Development and Injury.	GATA3 WT1	1.72e-05	7	32	2	31405951
Pubmed	Dynamic Expression of Sox2, Gata3, and Prox1 during Primary Auditory Neuron Development in the Mammalian Cochlea.	GATA3 MAFB	1.72e-05	7	32	2	28118374
Pubmed	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.	KICS2 OSBP2 ALMS1 MBP	2.23e-05	180	32	4	24104479
Pubmed	Hox11 paralogous genes are essential for metanephric kidney induction.	WT1 HOXC11	2.29e-05	8	32	2	12050119
Pubmed	Opalin, a transmembrane sialylglycoprotein located in the central nervous system myelin paranodal loop membrane.	CNTNAP1 MBP	2.29e-05	8	32	2	18490449
Pubmed	Distribution of monocarboxylate transporters in the peripheral nervous system suggests putative roles in lactate shuttling and myelination.	CNTNAP1 MBP	2.29e-05	8	32	2	25762662
Pubmed	AMOTL2 mono-ubiquitination by WWP1 promotes contact inhibition by facilitating LATS activation.	LATS2 PATJ	2.29e-05	8	32	2	34404733
Pubmed	Hippo Signaling Mediators Yap and Taz Are Required in the Epicardium for Coronary Vasculature Development.	WT1 LATS2	2.94e-05	9	32	2	27160901
Pubmed	A uniform procedure for the purification of CDK7/CycH/MAT1, CDK8/CycC and CDK9/CycT1.	POLR2A MBP	2.94e-05	9	32	2	15328539
Pubmed	Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity.	MALT1 USP9X	3.67e-05	10	32	2	26936881
Pubmed	The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.	LATS2 MBP	4.49e-05	11	32	2	15147269
Pubmed	Netrin-1 Confines Rhombic Lip-Derived Neurons to the CNS.	GATA3 MAFB	4.49e-05	11	32	2	29444422
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	MALT1 NCAM2 CPD HIVEP2 LATS2 PATJ ATXN7 MBP	4.64e-05	1489	32	8	28611215
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	HELZ LATS2 PATJ ALMS1 USP9X	5.13e-05	446	32	5	24255178
Pubmed	Innervation of the developing kidney in vivo and in vitro.	GATA3 WT1	5.38e-05	12	32	2	37439314
Pubmed	Molecular mechanisms underlying inner ear patterning defects in kreisler mutants.	GATA3 MAFB	5.38e-05	12	32	2	16325169
Pubmed	Impaired macroglial development and axonal conductivity contributes to the neuropathology of DYRK1A-related intellectual disability syndrome.	CNTNAP1 MBP	5.38e-05	12	32	2	36402907
Pubmed	Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages.	GATA3 MAFB	5.38e-05	12	32	2	31913118
Pubmed	CNS myelin paranodes require Nkx6-2 homeoprotein transcriptional activity for normal structure.	CNTNAP1 MBP	6.36e-05	13	32	2	15601927
Pubmed	A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects.	GATA3 WT1	6.36e-05	13	32	2	26859289
Pubmed	Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse.	CNTNAP1 MBP	6.36e-05	13	32	2	36793543
Pubmed	WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination.	CNTNAP1 MBP	6.36e-05	13	32	2	16723544
Pubmed	A Second Heart Field-Derived Vasculogenic Niche Contributes to Cardiac Lymphatics.	WT1 POLR2A	6.36e-05	13	32	2	31928974
Pubmed	Cardiac deletion of Smyd2 is dispensable for mouse heart development.	HELZ POLR2A	6.36e-05	13	32	2	20305823
Pubmed	A Gata3-Mafb transcriptional network directs post-synaptic differentiation in synapses specialized for hearing.	GATA3 MAFB	7.41e-05	14	32	2	24327562
Pubmed	Hoxa11 and Hoxd11 regulate branching morphogenesis of the ureteric bud in the developing kidney.	WT1 HOXC11	7.41e-05	14	32	2	11493536
Pubmed	Hoxb3 negatively regulates Hoxb1 expression in mouse hindbrain patterning.	GATA3 MAFB	7.41e-05	14	32	2	21320481
Pubmed	Deubiquitylase USP9X suppresses tumorigenesis by stabilizing large tumor suppressor kinase 2 (LATS2) in the Hippo pathway.	LATS2 USP9X	7.41e-05	14	32	2	29183995
Pubmed	Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease.	ADAMTS18 MUC5AC	7.41e-05	14	32	2	31242448
Pubmed	OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ.	LATS2 PATJ POLR2A	8.13e-05	91	32	3	30472188
Pubmed	FGF8 is essential for formation of the ductal system in the male reproductive tract.	GATA3 WT1	8.55e-05	15	32	2	22110055
Pubmed	The species-specific differences in the cAMP regulation of the tissue-type plasminogen activator gene between rat, mouse and human is caused by a one-nucleotide substitution in the cAMP-responsive element of the promoters.	ADAMTS18 MUC5AC	8.55e-05	15	32	2	7543410
Pubmed	β-catenin regulates the formation of multiple nephron segments in the mouse kidney.	WT1 MAFB	8.55e-05	15	32	2	31685872
Pubmed	Kif3a controls murine nephron number via GLI3 repressor, cell survival, and gene expression in a lineage-specific manner.	WT1 NCAM2	9.76e-05	16	32	2	23762375
Pubmed	Gbx2 is required for the morphogenesis of the mouse inner ear: a downstream candidate of hindbrain signaling.	GATA3 MAFB	9.76e-05	16	32	2	15829521
Pubmed	The embryonic expression pattern of 40 murine cDNAs homologous to Drosophila mutant genes (Dres): a comparative and topographic approach to predict gene function.	USP9X DEGS1	9.76e-05	16	32	2	9817915
Pubmed	Aristaless related homeobox gene, Arx, is implicated in mouse fetal Leydig cell differentiation possibly through expressing in the progenitor cells.	WT1 MAFB	9.76e-05	16	32	2	23840809
Pubmed	Candidate gene approach evaluates association between innate immunity genes and breast cancer risk in Korean women.	CNTNAP1 MBP	1.11e-04	17	32	2	19372141
Pubmed	Brain-specific Wt1 deletion leads to depressive-like behaviors in mice via the recruitment of Tet2 to modulate Epo expression.	WT1 MBP	1.11e-04	17	32	2	32393787
Pubmed	Conserved and Divergent Features of Human and Mouse Kidney Organogenesis.	WT1 MAFB	1.11e-04	17	32	2	29449453
Pubmed	Gata3 is a critical regulator of cochlear wiring.	GATA3 MAFB	1.24e-04	18	32	2	23426694
Pubmed	Six1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesis.	GATA3 WT1	1.24e-04	18	32	2	21281623
Pubmed	Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis.	WT1 POLR2A	1.24e-04	18	32	2	14628042
Pubmed	Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord.	GATA3 WT1	1.24e-04	18	32	2	30456369
Pubmed	Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation.	WT1 MAFB	1.24e-04	18	32	2	29113990
Pubmed	Hox10 genes function in kidney development in the differentiation and integration of the cortical stroma.	WT1 HOXC11	1.39e-04	19	32	2	21858105
Pubmed	The aryl hydrocarbon receptor promotes differentiation during mouse preimplantational embryo development.	GATA3 LATS2	1.39e-04	19	32	2	34478649
Pubmed	Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney.	GATA3 WT1	1.39e-04	19	32	2	16319112
Pubmed	Cep120 is essential for kidney stromal progenitor cell growth and differentiation.	GATA3 WT1	1.39e-04	19	32	2	38177914
Pubmed	Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen.	WT1 MUC5AC	1.39e-04	19	32	2	17855428
Pubmed	vHNF1 functions in distinct regulatory circuits to control ureteric bud branching and early nephrogenesis.	GATA3 WT1	1.54e-04	20	32	2	20040500
Pubmed	Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1.	NCAM2 POLR2A	1.54e-04	20	32	2	16009131
Pubmed	A census of human transcription factors: function, expression and evolution.	GATA3 WT1 MAFB HIVEP2 HOXC11 NFX1	1.58e-04	908	32	6	19274049
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	PTPN3 CPD LATS2 PATJ MBP	1.61e-04	569	32	5	30639242
Pubmed	MAFB is dispensable for the fetal testis morphogenesis and the maintenance of spermatogenesis in adult mice.	WT1 MAFB	1.70e-04	21	32	2	29324782
Pubmed	Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain.	MAFB MBP	1.87e-04	22	32	2	37364986
Pubmed	Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development.	MAFB RFX6	2.05e-04	23	32	2	28071588
Pubmed	Transcription Factor MafB Coordinates Epidermal Keratinocyte Differentiation.	GATA3 MAFB	2.24e-04	24	32	2	27208706
Pubmed	The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.	LATS2 PATJ	2.43e-04	25	32	2	21145499
Pubmed	Arrest of WNT/β-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries.	WT1 POLR2A	2.63e-04	26	32	2	34301885
Pubmed	Lats1 and Lats2 are required for the maintenance of multipotency in the Müllerian duct mesenchyme.	WT1 LATS2	2.84e-04	27	32	2	31575647
Pubmed	Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate.	WT1 SERPINE1	3.28e-04	29	32	2	27120339
Pubmed	Targeted Disruption of Lats1 and Lats2 in Mice Impairs Testis Development and Alters Somatic Cell Fate.	WT1 LATS2	3.75e-04	31	32	2	36362374
Pubmed	Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT).	GATA3 WT1	3.75e-04	31	32	2	29459093
Pubmed	NFX1-123 and poly(A) binding proteins synergistically augment activation of telomerase in human papillomavirus type 16 E6-expressing cells.	USP9X NFX1	4.00e-04	32	32	2	17267499
Pubmed	Convergence of the insulin and serotonin programs in the pancreatic β-cell.	MAFB RFX6	4.52e-04	34	32	2	22013016
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	HELZ MALT1 ALMS1 ATXN7 POLR2A IYD	4.77e-04	1116	32	6	31753913
Pubmed	Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity.	RFX6 MUC5AC	5.07e-04	36	32	2	27736991
Pubmed	β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development.	MAFB RFX6	5.07e-04	36	32	2	26901059
Pubmed	Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.	PTPN3 PATJ	5.07e-04	36	32	2	26053890
Pubmed	Transcription Factors YAP/TAZ and SRF Cooperate To Specify Renal Myofibroblasts in the Developing Mouse Kidney.	WT1 LATS2	5.35e-04	37	32	2	35918150
Pubmed	In vitro differentiation of mouse pluripotent stem cells into corticosteroid-producing adrenocortical cells.	GATA3 WT1	5.35e-04	37	32	2	39178848
Pubmed	Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.	GATA3 WT1	5.65e-04	38	32	2	27820600
Pubmed	Defining the molecular character of the developing and adult kidney podocyte.	WT1 MAFB	5.95e-04	39	32	2	21931791
Pubmed	HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2.	WT1 MAFB	6.26e-04	40	32	2	23362348
Pubmed	Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development.	GATA3 WT1	6.58e-04	41	32	2	30377232
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	HELZ ALMS1 MUC5AC	6.76e-04	187	32	3	26460568
Pubmed	Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons.	HIVEP2 MBP	6.90e-04	42	32	2	24997765
Pubmed	Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues.	NCAM2 MBP	6.90e-04	42	32	2	15146195
Pubmed	ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct.	ATXN7 POLR2A	7.57e-04	44	32	2	37682711
Pubmed	NANOG initiates epiblast fate through the coordination of pluripotency genes expression.	GATA3 LATS2	8.28e-04	46	32	2	35729116
Coexpression	CUI_TCF21_TARGETS_2_DN	GATA3 MALT1 MAFB HIVEP2 LATS2 ATXN7 USP9X DEGS1	4.98e-06	854	31	8	M1533
Coexpression	CUI_TCF21_TARGETS_2_DN	GATA3 MALT1 MAFB HIVEP2 LATS2 ATXN7 USP9X DEGS1	6.63e-06	888	31	8	MM1018
Coexpression	MEISSNER_NPC_HCP_WITH_H3K4ME2	GATA3 ADAMTS18 OSBP2 PATJ MBP PEAR1	2.12e-05	493	31	6	M1951
Coexpression	MEISSNER_NPC_HCP_WITH_H3K4ME2	GATA3 ADAMTS18 OSBP2 PATJ MBP PEAR1	2.40e-05	504	31	6	MM830
Coexpression	GSE21033_3H_VS_24H_POLYIC_STIM_DC_UP	HELZ PATJ POLR2A MBP	4.27e-05	166	31	4	M7722
Coexpression	FOURATI_BLOOD_TWINRIX_AGE_25_83YO_RESPONDERS_VS_POOR_RESPONDERS_0DY_UP	KICS2 MALT1 HIVEP2 ZNF550 USP9X CNTNAP1	5.62e-05	587	31	6	M40869
Coexpression	GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_UP	MALT1 PTPN3 OSBP2 ZNF550	8.47e-05	198	31	4	M4418
Coexpression	GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_UP	GATA3 ALMS1 POLR2A NFX1	8.64e-05	199	31	4	M3478
Coexpression	GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP	CPD DEGS1 MBP NFX1	8.81e-05	200	31	4	M6242
Coexpression	GSE7400_CTRL_VS_CSF3_IN_VIVO_TREATED_PBMC_UP	GATA3 MALT1 ATXN7 NFX1	8.81e-05	200	31	4	M5668
Coexpression	ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF	HIVEP2 LATS2 MBP SERPINE1	1.56e-04	232	31	4	M2613
Coexpression	SEAVEY_EPITHELIOID_HEMANGIOENDOTHELIOMA	WT1 LATS2 SERPINE1	1.81e-04	93	31	3	M42516
CoexpressionAtlas	kidney_adult_Podocyte_MafB_top-relative-expression-ranked_1000	WT1 MALT1 PTPN3 MAFB CPD HIVEP2 LATS2 DEGS1	2.00e-05	838	31	8	gudmap_kidney_adult_Podocyte_MafB_1000
CoexpressionAtlas	gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K2	GATA3 WT1 ADAMTS18 HOXC11 PATJ MBP	3.68e-05	441	31	6	gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K2
ToppCell	Mild/Remission-B_intermediate-1\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	WT1 ZNF488 PATJ PEAR1	1.58e-06	123	31	4	69b7f2f4604bf221a0ff581c51de743e8a4c0537
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Mesenchymal-Mes-Myofibroblast\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LATS2 PEAR1 SERPINE1 IYD	5.72e-06	170	31	4	489fc97f6002a577b882a8ff3c563b1e42041d38
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Mesenchymal-Mes-Myofibroblast-VLMC_L1-3_CYP1B1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LATS2 PEAR1 SERPINE1 IYD	5.72e-06	170	31	4	7d736e741799b67a7f022fc6766841c951ef8951
ToppCell	COVID_vent-Lymphocytic-T_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	GATA3 HIVEP2 PATJ MBP	1.02e-05	197	31	4	ad702e440a74d54cfdcb8bb1c66bd8e0e71ab04e
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6\|Thalamus / BrainAtlas - Mouse McCarroll V32	PTPN3 PATJ IYD	4.58e-05	100	31	3	1de3895e16f14ff32b901b18ce14d965afaa7e76
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Thalamus / BrainAtlas - Mouse McCarroll V32	PTPN3 PATJ IYD	4.58e-05	100	31	3	20675fc2ffc5ab63047d38da083b50d470f3db19
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora\|Thalamus / BrainAtlas - Mouse McCarroll V32	PTPN3 PATJ IYD	4.58e-05	100	31	3	ff1bdb511700a041a90034d1d30dfc25f51d6c82
ToppCell	Thalamus\|World / BrainAtlas - Mouse McCarroll V32	PTPN3 PATJ IYD	7.12e-05	116	31	3	5ddfb2dd5459ff6d7ae38163a38eae64fda283b7
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ZNF488 DEGS1 MBP	1.17e-04	137	31	3	80f1a6cfb48ccfba1c3545fdcd5fcb3157272aca
ToppCell	Leuk-UTI-Lymphocyte-T_NK-Treg\|Leuk-UTI / Disease, Lineage and Cell Type	GATA3 PTPN3 PATJ	1.62e-04	153	31	3	b24c693b142206d13b29c96faa7f79a1a22bc2ef
ToppCell	facs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAFB CNTNAP1 SERPINE1	1.71e-04	156	31	3	5caefdc6cc86f2ac52abe8c8da821db14f476915
ToppCell	facs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAFB CNTNAP1 SERPINE1	1.71e-04	156	31	3	758f57dc10fc5cad200bf5b310c10ec9b1405f23
ToppCell	Severe-B_naive-5\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	GATA3 ZNF550 PATJ	1.74e-04	157	31	3	a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCell	TCGA-Kidney-Solid_Tissue_Normal-Kidney-Kidney_normal_tissue-5\|TCGA-Kidney / Sample_Type by Project: Shred V9	WT1 ZNF488 IYD	1.78e-04	158	31	3	34b284a62cc3fb90429ce579fd8cb8a60178091b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GATA3 WT1 RFX6	1.81e-04	159	31	3	5ca96db4281abb5f646150ccf36adc66ab201c78
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAMTS18 MAFB LATS2	1.84e-04	160	31	3	dd16ca90feb3ae88b6409d6c278b4765da565514
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GATA3 WT1 MAFB	2.09e-04	167	31	3	b4ef07117d14da3d5fbced949e4dfcb01c392295
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GATA3 WT1 MAFB	2.09e-04	167	31	3	94fc7df7ca55cd722a8dbd153201a29891217473
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GATA3 WT1 MAFB	2.09e-04	167	31	3	eff3723fe60755272eca237459165e436e919ece
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GATA3 WT1 PEAR1	2.20e-04	170	31	3	876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GATA3 WT1 PEAR1	2.20e-04	170	31	3	1f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Mesenchymal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LATS2 PEAR1 SERPINE1	2.24e-04	171	31	3	4df4ee91fb9672f6541bd62dc0fb099fe014a65c
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Mesenchymal-Mes\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LATS2 PEAR1 SERPINE1	2.24e-04	171	31	3	c2a211352411c84e323175998f8a6d3fea77313b
ToppCell	facs-Skin-nan-24m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA3 MAFB MBP	2.28e-04	172	31	3	5ca89af7406e7e1a055dd60d6f89615f69e62324
ToppCell	Frontal_cortex-Macroglia\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ZNF488 DEGS1 MBP	2.32e-04	173	31	3	ac70145e093ef0df43811e7c67a865ccdd45a5e3
ToppCell	Posterior_cortex-Macroglia\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ZNF488 DEGS1 MBP	2.40e-04	175	31	3	8bc7a3856d04692989b2a1675ea6d9392261d55a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GATA3 WT1 PEAR1	2.40e-04	175	31	3	1b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCell	BAL-Mild-cDC_3\|Mild / Compartment, Disease Groups and Clusters	KICS2 CNTNAP1 MBP	2.44e-04	176	31	3	f9b0c3ced391e7ebe6b242d3f12ba14741f88d22
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS18 MAFB OSBP2	2.48e-04	177	31	3	1dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	CPD ALMS1 NFX1	2.48e-04	177	31	3	eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS18 MAFB OSBP2	2.48e-04	177	31	3	426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	WT1 HOXC11 PATJ	2.52e-04	178	31	3	544379f5a6145429762258d426b876bb36c112f5
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ZNF488 DEGS1 MBP	2.52e-04	178	31	3	b1357ceb84b83fab53c0394c1af73cbd009f571a
ToppCell	Globus_pallidus-Macroglia\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ZNF488 DEGS1 MBP	2.56e-04	179	31	3	ab50f711b004b96107f813c9a2526ec21d1c8027
ToppCell	Entopeduncular-Macroglia\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ZNF488 DEGS1 MBP	2.56e-04	179	31	3	f61974710a60aa0618fdb30d864fb9bc7c05ef21
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GATA3 WT1 PEAR1	2.65e-04	181	31	3	a2058d658f07ab6f0a28d2622f3090b4cde6f763
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GATA3 WT1 PEAR1	2.65e-04	181	31	3	526e858a848470b6d2d5248788004d9735ed3add
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GATA3 MALT1 ATXN7	2.69e-04	182	31	3	9ba85f621a846531a2a7861e9df695d288c9e149
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KICS2 NCAM2 MBP	2.69e-04	182	31	3	c00e503f442d44fbae73c5e2dc85be69e294e67a
ToppCell	RSV-Healthy-5\|Healthy / Virus stimulation, Condition and Cluster	GATA3 MALT1 DEGS1	2.78e-04	184	31	3	1e282d619ef8035437fabe0fd2aefda1c142f7f6
ToppCell	RSV-Healthy-5\|RSV / Virus stimulation, Condition and Cluster	GATA3 MALT1 DEGS1	2.78e-04	184	31	3	ba958f731de6c9eff60103d483e020e2c0c7af7c
ToppCell	control-Others-Megakaryocytes\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	OSBP2 PEAR1 SERPINE1	2.78e-04	184	31	3	213915f2889ce8ecbe5f7b19bc2b24ed8c5efe1d
ToppCell	control-Others\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	OSBP2 PEAR1 SERPINE1	2.78e-04	184	31	3	a63b39fcc570b554cf10e8e47c2c1e079034768f
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ADAMTS18 PTPN3 PATJ	2.87e-04	186	31	3	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	severe-Others\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	OSBP2 PEAR1 SERPINE1	2.87e-04	186	31	3	234a4bc7c3529daf8804f2a366887d02a47075cd
ToppCell	severe-Others-Megakaryocytes\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	OSBP2 PEAR1 SERPINE1	2.92e-04	187	31	3	ef16331d1e5abe6bde7f09793c4a87a6ac24e592
ToppCell	COVID-19-kidney-DCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GATA3 PTPN3 PATJ	2.96e-04	188	31	3	1d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS18 MAFB USP9X	2.96e-04	188	31	3	e99e3765b48392c987cf0c5ccbded0655637d7b7
ToppCell	COVID-19-kidney-CD-PC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GATA3 PTPN3 PATJ	2.96e-04	188	31	3	8f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell	severe_influenza-CD4+_Tcm\|severe_influenza / disease group, cell group and cell class (v2)	GATA3 PATJ CNTNAP1	2.96e-04	188	31	3	633e5545f49b1b864b0ffa5fc9688d270690f884
ToppCell	Endothelial-endothelial_cell_of_lymph_vessel\|World / Lineage, Cell type, age group and donor	PTPN3 OSBP2 PEAR1	2.96e-04	188	31	3	80910dcbb51990f2baed240f319456c0d3fa2065
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PTPN3 OSBP2 PEAR1	2.96e-04	188	31	3	c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PTPN3 OSBP2 PEAR1	2.96e-04	188	31	3	aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCell	COVID-19-lung-Secretory\|lung / Disease (COVID-19 only), tissue and cell type	PTPN3 PATJ MUC5AC	3.01e-04	189	31	3	84d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell	Healthy/Control-Platelet\|Healthy/Control / Disease group and Cell class	OSBP2 PEAR1 SERPINE1	3.01e-04	189	31	3	3de7f8d8b8451ed9a146cce499552e9a060e9099
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPN3 PATJ SERPINE1	3.01e-04	189	31	3	f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCell	mild-Others\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	OSBP2 PEAR1 SERPINE1	3.05e-04	190	31	3	782dc1b612ac1faad7cc2781bfda92a079830d38
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPN3 CPD MUC5AC	3.05e-04	190	31	3	6ea9fa08bd97bedcb21d3654467e7f8dd74c8fd0
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PTPN3 OSBP2 PEAR1	3.05e-04	190	31	3	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	droplet-Skin-nan-21m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA3 MAFB MBP	3.10e-04	191	31	3	c5ef34d138cd797029dfefaf4c52d16ba6a76c38
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	WT1 ADAMTS18 MAFB	3.10e-04	191	31	3	156b467187331ac6ca390d6ca861d9670bb7b956
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GATA3 MALT1 PATJ	3.10e-04	191	31	3	9c747f8cc1cdce45e839b661d782e1e8cfb79578
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP2 MBP SERPINE1	3.15e-04	192	31	3	8b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell	COVID-19-kidney-CNT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GATA3 PTPN3 PATJ	3.15e-04	192	31	3	760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GATA3 NCAM2 MBP	3.15e-04	192	31	3	0bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GATA3 HIVEP2 PATJ	3.15e-04	192	31	3	7ab626a516b07d899175ff12f1c8257688324e4b
ToppCell	LA-14._Fibroblast_III\|LA / Chamber and Cluster_Paper	WT1 HIVEP2 SERPINE1	3.20e-04	193	31	3	7426c291bac59e539c427bcaae18abc7d397d44e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GATA3 HIVEP2 PATJ	3.20e-04	193	31	3	194b49c152e3e3f599068ec88a7f0af6427b743a
ToppCell	COVID-19_Mild-CD4+_Tcm\|COVID-19_Mild / Disease condition and Cell class	GATA3 MALT1 PATJ	3.25e-04	194	31	3	3be2b1c81e668ffdf593ff41d3ba211c26d77671
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	WT1 NCAM2 SERPINE1	3.25e-04	194	31	3	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GATA3 PATJ MBP	3.25e-04	194	31	3	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GATA3 MALT1 HIVEP2	3.25e-04	194	31	3	3d6f2d190dd50804afea299957cc44c2bb756134
ToppCell	LA-14._Fibroblast_III\|World / Chamber and Cluster_Paper	WT1 HIVEP2 SERPINE1	3.25e-04	194	31	3	803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GATA3 HIVEP2 PATJ	3.25e-04	194	31	3	a44be2f021cfdd0fcdc698c3f04d66db7a1aa6c2
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	GATA3 HIVEP2 PATJ	3.30e-04	195	31	3	4bdedd924564a260841a9153604026b57487c83d
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	GATA3 HIVEP2 PATJ	3.30e-04	195	31	3	22191d361af136942508f1553ff41a626ed982ad
ToppCell	mild_COVID-19_(asymptomatic)-CD4+_Tcm\|World / disease group, cell group and cell class (v2)	GATA3 PATJ MBP	3.30e-04	195	31	3	a72bb5b1b15dd1ab70ced5622d94499caff8bb6b
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MALT1 MAFB HIVEP2	3.34e-04	196	31	3	c2bbb48c4aa979b03cb6f4ce9f351f492977c992
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	OSBP2 PATJ SERPINE1	3.34e-04	196	31	3	b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell	healthy_donor-Lymphocytic-T_cell-Gamma_Delta_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	GATA3 HIVEP2 PATJ	3.34e-04	196	31	3	6eabbac1625f715531bae562a28da27664572600
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MALT1 MAFB HIVEP2	3.34e-04	196	31	3	64c2abc0087bf2ae547932377f3662e3be1cc63e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GATA3 PTPN3 PATJ	3.34e-04	196	31	3	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	COPD-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	MALT1 CPD PATJ	3.34e-04	196	31	3	c9bdd505c3ab380ed7b272aa518df31a0a706a06
ToppCell	distal-Endothelial-Lymphatic-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS18 PTPN3 ZNF488	3.34e-04	196	31	3	b0f23dc802a2c2a56a08d398a464ea78b58ade4c
ToppCell	healthy_donor-Lymphocytic-T_cell-CD4+_Memory_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	GATA3 HIVEP2 PATJ	3.40e-04	197	31	3	c842d169dfce9af3ed7c01dc7e940c0bdd21388c
ToppCell	healthy_donor-Lymphocytic-T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	GATA3 HIVEP2 PATJ	3.40e-04	197	31	3	63d0f06e150e7eb800ecb70e97b9d12a01c84e37
ToppCell	COVID_vent-Lymphocytic-T_cell-CD4+_Memory_T_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	GATA3 HIVEP2 PATJ	3.45e-04	198	31	3	58f208b76cb0adcecdf632d92f92833a06f9bf71
ToppCell	Skin\|World / Skin and Kidney Cells in Lupus Nephritis Patients.	GATA3 MAFB DEGS1	3.50e-04	199	31	3	6be1340413ee868c610b6e3f58c65b493eb22bb5
ToppCell	mild-CD4+_Tcm\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	GATA3 MALT1 HIVEP2	3.50e-04	199	31	3	06c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAM2 ZNF488 DEGS1	3.55e-04	200	31	3	f0c338877e39226a90c4effe12f6501d33542a73
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAM2 DEGS1 MBP	3.55e-04	200	31	3	56f1f007ba8c9188a4b10e52744f1e50dc0f155a
ToppCell	Skin-Keratinocytes\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	GATA3 MAFB DEGS1	3.55e-04	200	31	3	59d72395199bc30df0e811fbc99149694e208860
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Mild / Disease, condition lineage and cell class	GATA3 HIVEP2 ATXN7	3.55e-04	200	31	3	d9e8a0d047d4403fb7265fde7448e23a7780785c
Drug	YS19	DEGS1 MBP	1.79e-06	2	31	2	CID000200844
Drug	Cinnarizine [298-57-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A	HELZ MALT1 PATJ MUC5AC NFX1	6.69e-06	198	31	5	3175_DN
Drug	STOCK1N-28457; Up 200; 20uM; MCF7; HT_HG-U133A	CPD HIVEP2 MUC5AC CNTNAP1 NFX1	6.85e-06	199	31	5	6869_UP
Drug	Endyinasl	PTPN3 MBP	1.79e-05	5	31	2	CID005492616
Drug	oxybenzone	HIVEP2 DEGS1 MBP	2.02e-05	39	31	3	CID000004632
Drug	1y2g	WT1 PTPN3 CPD CNTNAP1	2.75e-05	129	31	4	CID005287936
Drug	AC1L9K1W	ATXN7 DEGS1 MBP	3.12e-05	45	31	3	CID000446744
Drug	MSC194	NCAM2 DEGS1 MBP	4.29e-05	50	31	3	CID003000663
Drug	MDL 18,962	DEGS1 MBP	5.00e-05	8	31	2	CID000071996
Drug	1XS7	LATS2 MBP IYD	9.43e-05	65	31	3	CID000449218
Drug	Betamethasone [378-44-9]; Up 200; 10.2uM; HL60; HG-U133A	MAFB CPD ATXN7 NFX1	1.07e-04	183	31	4	1590_UP
Drug	Halcinonide [3093-35-4]; Up 200; 8.8uM; HL60; HT_HG-U133A	MAFB CPD HOXC11 MBP	1.10e-04	184	31	4	2185_UP
Drug	Apigenin [520-36-5]; Down 200; 14.8uM; HL60; HT_HG-U133A	WT1 MALT1 MAFB ALMS1	1.10e-04	184	31	4	1321_DN
Drug	0179445-0000 [211246-22-9]; Down 200; 10uM; MCF7; HT_HG-U133A	HIVEP2 ALMS1 MBP NFX1	1.12e-04	185	31	4	4755_DN
Drug	Bluo-gal	WT1 MBP	1.17e-04	12	31	2	CID000126898
Drug	Triamcinolone [124-94-7]; Up 200; 10.2uM; HL60; HG-U133A	MAFB CPD ATXN7 NFX1	1.19e-04	188	31	4	1395_UP
Drug	Scoulerine [6451-73-6]; Up 200; 12.2uM; HL60; HG-U133A	MALT1 CPD CNTNAP1 NFX1	1.21e-04	189	31	4	1742_UP
Drug	Apigenin [520-36-5]; Down 200; 14.8uM; MCF7; HT_HG-U133A	MALT1 MAFB ALMS1 POLR2A	1.21e-04	189	31	4	4401_DN
Drug	5151277; Up 200; 14uM; MCF7; HT_HG-U133A_EA	NCAM2 MAFB PATJ DEGS1	1.37e-04	195	31	4	903_UP
Drug	Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Down 200; 7.8uM; MCF7; HT_HG-U133A	CPD HIVEP2 ALMS1 DEGS1	1.37e-04	195	31	4	5307_DN
Drug	Quinidine hydrochloride monohydrate [6151-40-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A	MAFB CPD PATJ NFX1	1.37e-04	195	31	4	3191_DN
Drug	pirfenidone	PTPN3 SERPINE1	1.39e-04	13	31	2	ctd:C093844
Drug	Spiramycin [8025-81-8]; Down 200; 4.8uM; PC3; HT_HG-U133A	WT1 CPD HOXC11 PATJ	1.40e-04	196	31	4	3762_DN
Drug	2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A	MALT1 CPD DEGS1 NFX1	1.40e-04	196	31	4	6934_UP
Drug	Streptomycin sulfate [3810-74-0]; Down 200; 2.8uM; HL60; HG-U133A	MAFB CPD ALMS1 NFX1	1.42e-04	197	31	4	1578_DN
Drug	Nadide [53-84-9]; Down 200; 6uM; MCF7; HT_HG-U133A	NCAM2 CPD ALMS1 NFX1	1.42e-04	197	31	4	7227_DN
Drug	Chloroquine diphosphate [50-63-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A	HELZ MALT1 CPD NFX1	1.42e-04	197	31	4	7012_DN
Drug	Sulfachloropyridazine [80-32-0]; Down 200; 14uM; PC3; HT_HG-U133A	HOXC11 PATJ ATXN7 NFX1	1.42e-04	197	31	4	3769_DN
Drug	Pyrilamine maleate [59-33-6]; Down 200; 10uM; MCF7; HT_HG-U133A	MALT1 CPD PATJ NFX1	1.42e-04	197	31	4	7223_DN
Drug	MK-886; Down 200; 1uM; MCF7; HG-U133A	MALT1 CPD HIVEP2 SERPINE1	1.42e-04	197	31	4	601_DN
Drug	3-amino-4-phenylbutan-2-ol	GATA3 WT1 MALT1	1.44e-04	75	31	3	CID004634234
Drug	Scopolamin-N-oxide hydrobromide [6106-81-6]; Down 200; 10uM; HL60; HG-U133A	CPD ALMS1 USP9X POLR2A	1.45e-04	198	31	4	1415_DN
Drug	Cefoperazone dihydrate; Up 200; 5.8uM; PC3; HT_HG-U133A	GATA3 HOXC11 SERPINE1 NFX1	1.45e-04	198	31	4	6323_UP
Drug	(S)-(-)-Atenolol [93379-54-5]; Down 200; 15uM; MCF7; HT_HG-U133A	PATJ ALMS1 POLR2A NFX1	1.45e-04	198	31	4	5325_DN
Drug	Scopolamine hydrochloride [55-16-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A	MALT1 MUC5AC DEGS1 NFX1	1.48e-04	199	31	4	3357_DN
Drug	Benzonatate [104-31-4]; Up 200; 6.6uM; MCF7; HT_HG-U133A	MALT1 PATJ ALMS1 MBP	1.48e-04	199	31	4	1679_UP
Drug	Cephalosporanic acid, 7-amino [957-68-6]; Up 200; 14.6uM; MCF7; HT_HG-U133A	MALT1 NCAM2 ALMS1 NFX1	1.48e-04	199	31	4	4826_UP
Drug	Ethynylestradiol 3-methyl ether [72-33-3]; Down 200; 12.8uM; MCF7; HT_HG-U133A	MALT1 CPD ALMS1 MUC5AC	1.48e-04	199	31	4	3346_DN
Drug	Antipyrine, 4-hydroxy [1672-63-5]; Down 200; 19.6uM; PC3; HT_HG-U133A	GATA3 WT1 PATJ NFX1	1.51e-04	200	31	4	4095_DN
Drug	1pxm	GATA3 WT1 MUC5AC	1.62e-04	78	31	3	CID000447959
Disease	asthma (biomarker_via_orthology)	GATA3 MUC5AC SERPINE1	3.61e-05	59	32	3	DOID:2841 (biomarker_via_orthology)
Disease	N-acetylhistidine measurement	ALMS1 SERPINE1	6.23e-05	11	32	2	EFO_0800022
Disease	glaucoma (is_marker_for)	MUC5AC SERPINE1	2.14e-04	20	32	2	DOID:1686 (is_marker_for)
Disease	asthma (is_marker_for)	GATA3 MUC5AC SERPINE1	3.44e-04	126	32	3	DOID:2841 (is_marker_for)
Disease	thoracic aortic aneurysm	PTPN3 MBP	4.86e-04	30	32	2	EFO_0004282

Protein segments in the cluster

Peptide	Gene	Start	Entry
HTNEPKAAHEYHPGS	CNTNAP1	1316	P78357
RKHHSPSPQHQDYVA	ALMS1	2901	Q8TCU4
AATPYLHHPGDSHSG	COMMD5	6	Q9GZQ3
AQEHNYSSPAGHHPH	ADAMTS18	186	Q8TE60
PHSTSGLYPHHTEHG	RFX6	711	Q8HWS3
HHPGYLSDSHFIPDQ	PTPN3	166	P26045
PHHAYPGAGVAHDEL	MAFB	141	Q9Y5Q3
HSLQDPFHGVYHSHP	MALT1	751	Q9UDY8
HQHQHPPKGYGASVE	LATS2	226	Q9NRM7
HYDSPKNSHIPGHYD	PEAR1	1006	Q5VY43
SAVHQHSYHPSGSKP	NFX1	66	Q12986
HAQDGSSESSYKHHP	MUC5AC	26	P98088
HHAFLSQGSAPYPHH	HELZ	1521	P42694
HHPPSAAHYVFSKHG	OSBP2	626	Q969R2
KLDCHYSGHHPQPAS	ATXN7	506	O15265
HHPHSYREAPKGVDQ	KICS2	331	Q96MD2
GQHPDTHHPGLSHSY	GATA3	21	P23771
SSYQPIQPKDFHHHH	CPD	491	O75976
VGYHNEHHDFPNIPG	DEGS1	256	O15121
KNEGSYGGHHHPSAP	HOXC11	116	O43248
GKDSHHPARTAHYGS	MBP	191	P02686
VEHIPFSHNHYPEKE	IYD	71	Q6PHW0
GSAVHHPPSYVAHLA	SERPINE1	21	P05121
NHVHGQPYTGPAAHH	USP9X	2511	Q93008
SHHKKEHAGPDPHSQ	ZNF488	296	Q96MN9
FNKPDSHGGVPIHHY	NCAM2	516	O15394
HPQAHAPEYTSAHAP	SPEM3	341	A0A1B0GUW6
TGYHLGSPTAEHHPE	PATJ	1776	Q8NI35
HSTHPDDEDSGPYKH	POLR2A	606	P24928
GTPSYGHTPSHHAAQ	WT1	156	P19544
QHHPIHTGEKPYECS	ZNF550	276	Q7Z398
AGSYSLSVPGHHHQK	HIVEP2	1011	P31629