Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G-protein beta/gamma-subunit complex binding	GNAT3 GNAS GNAT2	1.31e-05	25	37	3	GO:0031683
GeneOntologyBiologicalProcess	intermediate filament cytoskeleton organization	KRT13 DST KRT25 KRT28	2.92e-05	99	37	4	GO:0045104
GeneOntologyBiologicalProcess	intermediate filament-based process	KRT13 DST KRT25 KRT28	3.04e-05	100	37	4	GO:0045103
GeneOntologyCellularComponent	heterotrimeric G-protein complex	GNAT3 GNAS GNAT2	3.21e-05	35	37	3	GO:0005834
GeneOntologyCellularComponent	GTPase complex	GNAT3 GNAS GNAT2	5.19e-05	41	37	3	GO:1905360
GeneOntologyCellularComponent	intermediate filament cytoskeleton	KRT13 DST KRT25 KRT28 DISC1	9.52e-05	263	37	5	GO:0045111
GeneOntologyCellularComponent	extrinsic component of cytoplasmic side of plasma membrane	GNAT3 GNAS GNAT2	1.33e-04	56	37	3	GO:0031234
GeneOntologyCellularComponent	ATAC complex	TADA2A MAP3K7	2.74e-04	14	37	2	GO:0140672
GeneOntologyCellularComponent	cytoplasmic side of plasma membrane	GNAT3 GNAS DST GNAT2	3.12e-04	185	37	4	GO:0009898
GeneOntologyCellularComponent	photoreceptor inner segment	GNAT3 GNAT2 FAM161A	3.54e-04	78	37	3	GO:0001917
GeneOntologyCellularComponent	intermediate filament	KRT13 DST KRT25 KRT28	6.75e-04	227	37	4	GO:0005882
GeneOntologyCellularComponent	cytoplasmic side of membrane	GNAT3 GNAS DST GNAT2	7.09e-04	230	37	4	GO:0098562
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	HAUS6 KRT13 DST FAM161A KRT25 KRT28 DISC1	8.83e-04	899	37	7	GO:0099513
GeneOntologyCellularComponent	spindle	HAUS6 TADA2A FAM161A BUB1B CEP63	1.37e-03	471	37	5	GO:0005819
GeneOntologyCellularComponent	extrinsic component of plasma membrane	GNAT3 GNAS GNAT2	1.82e-03	137	37	3	GO:0019897
GeneOntologyCellularComponent	photoreceptor cell cilium	GNAT3 GNAT2 FAM161A	1.89e-03	139	37	3	GO:0097733
GeneOntologyCellularComponent	centrosome	TRIM43 HAUS6 FAM161A DISC1 BUB1B CEP63	2.15e-03	770	37	6	GO:0005813
GeneOntologyCellularComponent	SAGA-type complex	TADA2A MAP3K7	2.17e-03	39	37	2	GO:0070461
GeneOntologyCellularComponent	9+0 non-motile cilium	GNAT3 GNAT2 FAM161A	2.49e-03	153	37	3	GO:0097731
GeneOntologyCellularComponent	supramolecular fiber	HAUS6 KRT13 DST FAM161A KRT25 KRT28 DISC1	4.14e-03	1179	37	7	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	HAUS6 KRT13 DST FAM161A KRT25 KRT28 DISC1	4.30e-03	1187	37	7	GO:0099081
GeneOntologyCellularComponent	ciliary base	MOK DISC1	4.42e-03	56	37	2	GO:0097546
GeneOntologyCellularComponent	non-motile cilium	GNAT3 GNAT2 FAM161A	4.99e-03	196	37	3	GO:0097730
GeneOntologyCellularComponent	microtubule organizing center	TRIM43 HAUS6 FAM161A DISC1 BUB1B CEP63	5.14e-03	919	37	6	GO:0005815
GeneOntologyCellularComponent	mitotic spindle	HAUS6 TADA2A FAM161A	5.35e-03	201	37	3	GO:0072686
Domain	G-alpha	GNAT3 GNAS GNAT2	3.62e-06	16	36	3	PF00503
Domain	GproteinA_insert	GNAT3 GNAS GNAT2	3.62e-06	16	36	3	IPR011025
Domain	G_alpha	GNAT3 GNAS GNAT2	3.62e-06	16	36	3	SM00275
Domain	-	GNAT3 GNAS GNAT2	3.62e-06	16	36	3	1.10.400.10
Domain	Gprotein_alpha_su	GNAT3 GNAS GNAT2	4.39e-06	17	36	3	IPR001019
Domain	Keratin_I	KRT13 KRT25 KRT28	8.25e-05	44	36	3	IPR002957
Domain	Gprotein_alpha_I	GNAT3 GNAT2	1.00e-04	8	36	2	IPR001408
Domain	Filament	KRT13 KRT25 KRT28	3.44e-04	71	36	3	SM01391
Domain	IF	KRT13 KRT25 KRT28	3.58e-04	72	36	3	PS00226
Domain	Filament	KRT13 KRT25 KRT28	3.73e-04	73	36	3	PF00038
Domain	IF	KRT13 KRT25 KRT28	4.20e-04	76	36	3	IPR001664
Domain	Kinase-like_dom	MOK DST MAP3K7 MATK BUB1B	3.62e-03	542	36	5	IPR011009
Domain	SH3_1	LASP1 DST MATK	3.84e-03	164	36	3	PF00018
Domain	BBOX	TRIM43B TRIM43	7.81e-03	69	36	2	SM00336
Domain	Butyrophylin	TRIM43B TRIM43	8.03e-03	70	36	2	IPR003879
Domain	SH3	LASP1 DST MATK	8.22e-03	216	36	3	PS50002
Domain	-	TRIM43B TRIM43	8.26e-03	71	36	2	4.10.45.10
Domain	SH3_domain	LASP1 DST MATK	8.65e-03	220	36	3	IPR001452
Domain	ZF_BBOX	TRIM43B TRIM43	1.04e-02	80	36	2	PS50119
Domain	Znf_B-box	TRIM43B TRIM43	1.06e-02	81	36	2	IPR000315
Domain	PROTEIN_KINASE_ATP	MOK MAP3K7 MATK BUB1B	1.14e-02	459	36	4	PS00107
Domain	EF-hand_7	CALB2 DST	1.17e-02	85	36	2	PF13499
Domain	SPRY	TRIM43B TRIM43	1.22e-02	87	36	2	SM00449
Domain	Prot_kinase_dom	MOK MAP3K7 MATK BUB1B	1.41e-02	489	36	4	IPR000719
Domain	SPRY	TRIM43B TRIM43	1.41e-02	94	36	2	PF00622
Domain	SPRY_dom	TRIM43B TRIM43	1.41e-02	94	36	2	IPR003877
Domain	B30.2/SPRY	TRIM43B TRIM43	1.44e-02	95	36	2	IPR001870
Domain	B302_SPRY	TRIM43B TRIM43	1.44e-02	95	36	2	PS50188
Domain	PROTEIN_KINASE_DOM	MOK MAP3K7 MATK BUB1B	1.45e-02	493	36	4	PS50011
Pathway	WP_PURINERGIC_SIGNALING	GNAT3 GNAS GNAT2	4.55e-05	33	30	3	M39855
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	GNAT3 RGSL1 GNAS	1.41e-04	48	30	3	M10775
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	CWF19L2 PPIL2 LASP1 GNAS HUWE1 TRIP11 HDLBP	2.53e-06	588	37	7	38580884
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	PPIL2 GNAS HUWE1 DST	2.83e-06	92	37	4	15840729
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	LASP1 GNAS HUWE1 DST GNAT2 NIPSNAP1 HDLBP	3.62e-06	621	37	7	22794259
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	HAUS6 HUWE1 FANCM ARHGEF10L	4.11e-06	101	37	4	10997877
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	PPIL2 HAUS6 HUWE1 DST ZNF512 MAP3K7 BUB1B	4.64e-06	645	37	7	25281560
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	HAUS6 TADA2A HUWE1 DST ZMYM5 BUB1B	4.93e-06	418	37	6	34709266
Pubmed	Mutations in the helix termination motif of mouse type I IRS keratin genes impair the assembly of keratin intermediate filament.	KRT25 KRT28	6.60e-06	4	37	2	17920809
Pubmed	Golf: an olfactory neuron specific-G protein involved in odorant signal transduction.	GNAS GNAT2	6.60e-06	4	37	2	2499043
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	LASP1 DST ARHGEF10L HDLBP ESRP1	7.76e-06	258	37	5	37794589
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	TRIM43B GNAT3 HUWE1 DST FAM186B KRT28 DISC1	1.09e-05	736	37	7	29676528
Pubmed	Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat.	GNAT3 GNAT2	1.10e-05	5	37	2	15886333
Pubmed	A new mouse model for retinal degeneration due to Fam161a deficiency.	GNAT2 FAM161A	1.65e-05	6	37	2	33479377
Pubmed	Immunohistochemical analysis of Disc1 expression in the developing and adult hippocampus.	CALB2 DISC1	1.65e-05	6	37	2	18620078
Pubmed	Proximity labeling reveals dynamic changes in the SQSTM1 protein network.	HAUS6 ZNF512 MAP3K7 NIPSNAP1 BUB1B	2.25e-05	322	37	5	39098523
Pubmed	The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development.	MAP3K7 ARHGEF10L ESRP1	3.46e-05	59	37	3	26371508
Pubmed	Spontaneous and induced mouse mutations with cerebellar dysfunctions: behavior and neurochemistry.	CALB2 DST	3.95e-05	9	37	2	16499884
Pubmed	New consensus nomenclature for mammalian keratins.	KRT13 KRT25 KRT28	4.21e-05	63	37	3	16831889
Pubmed	The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2.	GNAT3 GNAT2	4.93e-05	10	37	2	8521505
Pubmed	Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?	CYP1A1 TADA2A CPT2 DISC1	5.16e-05	192	37	4	20602615
Pubmed	The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain.	KRT25 KRT28	7.22e-05	12	37	2	15617563
Pubmed	Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein.	GNAT3 GNAT2	8.53e-05	13	37	2	8208289
Pubmed	Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins.	GNAT3 GNAT2	8.53e-05	13	37	2	16892066
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	CWF19L2 PPIL2 LASP1 ZMYM5 HDLBP	1.03e-04	444	37	5	34795231
Pubmed	METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.	GNAT3 GNAS GNAT2 HDLBP	1.05e-04	231	37	4	36597993
Pubmed	Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.	TRIM43B TRIM43	1.15e-04	15	37	2	19703589
Pubmed	Cloning and characterization of the human phosphoinositide-specific phospholipase C-beta 1 (PLC beta 1).	GNAT3 GNAT2	1.15e-04	15	37	2	11118617
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	GNAS HUWE1 DST CPT2 ZNF512 MAP3K7 TRIP11 NIPSNAP1	1.45e-04	1496	37	8	32877691
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	HUWE1 DST MAP3K7 NIPSNAP1 HDLBP	1.50e-04	481	37	5	28190767
Pubmed	mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.	DST NALCN HDLBP	1.57e-04	98	37	3	34943047
Pubmed	A human MAP kinase interactome.	KRT13 DST ZNF839 MAP3K7 HDLBP	1.57e-04	486	37	5	20936779
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	GNAS HUWE1 DST CPT2 MAP3K7 NIPSNAP1 HDLBP	1.82e-04	1149	37	7	35446349
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	GNAT3 HAUS6 LASP1 GNAS GNAT2 BUB1B CEP63	1.88e-04	1155	37	7	20360068
Pubmed	SOCS2 Binds to and Regulates EphA2 through Multiple Mechanisms.	GNAS DST BUB1B	2.21e-04	110	37	3	28883622
Pubmed	DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.	DISC1 CEP63	2.51e-04	22	37	2	12812986
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	GNAS HUWE1 DST ZNF512 HDLBP	2.72e-04	547	37	5	37267103
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	DST DISC1 CEP63	2.86e-04	120	37	3	31413325
Pubmed	Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human.	GNAS GNAT2	2.99e-04	24	37	2	2902634
Pubmed	Intermediate phenotypes identify divergent pathways to Alzheimer's disease.	RGSL1 DISC1	3.25e-04	25	37	2	20574532
Pubmed	Vti1b promotes TRPV1 sensitization during inflammatory pain.	LASP1 DST KRT28	3.37e-04	127	37	3	30335684
Pubmed	Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.	TADA2A MAP3K7	3.80e-04	27	37	2	18838386
Pubmed	G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development.	GNAS GNAT2	4.09e-04	28	37	2	8858601
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	HAUS6 LASP1 DST TRIP11 HDLBP BUB1B	4.21e-04	934	37	6	33916271
Pubmed	Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.	CYP1A1 GNAS	4.39e-04	29	37	2	21909115
Pubmed	MLL1 is essential for retinal neurogenesis and horizontal inner neuron integrity.	CALB2 GNAT2	4.39e-04	29	37	2	30093671
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	HAUS6 FAM161A CEP63	5.07e-04	146	37	3	21399614
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	DST DISC1 CEP63	5.59e-04	151	37	3	17043677
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	LASP1 GNAS HUWE1 DST NIPSNAP1 HDLBP	6.84e-04	1024	37	6	24711643
Pubmed	Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966.	TRIP11 CEP63	7.16e-04	37	37	2	19266077
Pubmed	Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.	HAUS6 MAP3K7 CEP63	7.76e-04	169	37	3	31462741
Pubmed	Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.	LASP1 GNAS DST BUB1B	8.51e-04	401	37	4	25852190
Pubmed	ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development.	MAP3K7 ESRP1	9.23e-04	42	37	2	29107558
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	PPIL2 HAUS6 LASP1 ZNF512 HDLBP	9.68e-04	724	37	5	36232890
Pubmed	Pooled-matrix protein interaction screens using Barcode Fusion Genetics.	KRT13 LASP1 FAM161A CEP63	1.00e-03	419	37	4	27107012
Interaction	CEP63 interactions	CWF19L2 HAUS6 DST FAM161A DISC1 BUB1B CEP63	3.19e-08	179	37	7	int:CEP63
Interaction	MED4 interactions	HAUS6 TADA2A HUWE1 DST MAP3K7 TRIP11 BUB1B CEP63	1.27e-06	450	37	8	int:MED4
Interaction	PCNT interactions	TRIM43 HUWE1 DST TRIP11 DISC1 CEP63	4.68e-06	241	37	6	int:PCNT
Interaction	CCDC102B interactions	CWF19L2 MAP3K7 FAM161A DISC1 HDLBP	7.94e-06	151	37	5	int:CCDC102B
Interaction	FBF1 interactions	HAUS6 KRT13 TADA2A LASP1 CEP63	1.45e-05	171	37	5	int:FBF1
Interaction	TRIM37 interactions	CWF19L2 HAUS6 GNAS HUWE1 FAM161A DISC1 BUB1B CEP63	1.51e-05	630	37	8	int:TRIM37
Interaction	CDC5L interactions	CWF19L2 PPIL2 TADA2A GNAS HUWE1 DST DISC1 HDLBP BUB1B	1.82e-05	855	37	9	int:CDC5L
Interaction	CEP57L1 interactions	KRT13 FAM161A DISC1 CEP63	2.72e-05	95	37	4	int:CEP57L1
Interaction	TRIM27 interactions	TRIM43 CWF19L2 LASP1 FANCM MAP3K7 FAM161A DISC1	3.57e-05	514	37	7	int:TRIM27
Interaction	NAA50 interactions	MOK CYP1A1 BUB1B CEP63	3.59e-05	102	37	4	int:NAA50
Interaction	CCHCR1 interactions	HAUS6 KRT13 TADA2A DISC1 CEP63	5.88e-05	229	37	5	int:CCHCR1
Interaction	TNIK interactions	HUWE1 DST MAP3K7 DISC1 HDLBP CEP63	6.22e-05	381	37	6	int:TNIK
Interaction	KRT71 interactions	KRT13 KRT25 KRT28	6.68e-05	43	37	3	int:KRT71
Interaction	GAS8 interactions	CWF19L2 LASP1 FAM161A DISC1	7.95e-05	125	37	4	int:GAS8
Interaction	NHP2 interactions	CWF19L2 HUWE1 ARHGEF10L HDLBP	9.54e-05	131	37	4	int:NHP2
Interaction	KRT81 interactions	KRT13 KRT25 KRT28	1.25e-04	53	37	3	int:KRT81
Interaction	KRT8 interactions	KRT13 TADA2A TRIP11 KRT25 KRT28 BUB1B	1.39e-04	441	37	6	int:KRT8
Interaction	PCNX4 interactions	DISC1 CEP63	1.46e-04	10	37	2	int:PCNX4
Interaction	KANK2 interactions	CWF19L2 HUWE1 ZNF512 FAM161A CEP63	1.64e-04	285	37	5	int:KANK2
Interaction	KRT72 interactions	KRT13 KRT25 KRT28	1.73e-04	59	37	3	int:KRT72
Interaction	KRT79 interactions	KRT13 KRT25 KRT28	1.73e-04	59	37	3	int:KRT79
Interaction	KRT4 interactions	KRT13 KRT25 KRT28	2.00e-04	62	37	3	int:KRT4
Interaction	SSR3 interactions	TRIM43B TRIM43 ARHGEF10L HDLBP	2.01e-04	159	37	4	int:SSR3
Interaction	CARD9 interactions	CWF19L2 FAM161A DISC1 ZMYM5	2.32e-04	165	37	4	int:CARD9
Interaction	RTL8B interactions	KRT13 TADA2A	2.53e-04	13	37	2	int:RTL8B
Interaction	NRIP1 interactions	CWF19L2 HUWE1 DST MAP3K7	2.60e-04	170	37	4	int:NRIP1
Interaction	SPTAN1 interactions	LASP1 DST TRIP11 DISC1 HDLBP CEP63	2.62e-04	496	37	6	int:SPTAN1
Interaction	DCTN1 interactions	HAUS6 LASP1 HUWE1 DST FAM161A DISC1	2.65e-04	497	37	6	int:DCTN1
Interaction	BFSP2 interactions	TRIP11 DISC1 CEP63	2.75e-04	69	37	3	int:BFSP2
Interaction	LZTS2 interactions	CWF19L2 LASP1 HUWE1 MAP3K7 FAM161A CEP63	3.11e-04	512	37	6	int:LZTS2
Interaction	HGS interactions	KRT13 TADA2A LASP1 MAP3K7 KRT25 CEP63	3.48e-04	523	37	6	int:HGS
Interaction	KRT6C interactions	KRT13 KRT25 KRT28	3.65e-04	76	37	3	int:KRT6C
Interaction	PHF21A interactions	HAUS6 TADA2A HUWE1 DST BUB1B	3.86e-04	343	37	5	int:PHF21A
Interaction	CEP44 interactions	HAUS6 FAM161A DISC1 CEP63	3.88e-04	189	37	4	int:CEP44
Interaction	GRIPAP1 interactions	CWF19L2 HAUS6 FAM161A DISC1	4.12e-04	192	37	4	int:GRIPAP1
Interaction	KRT5 interactions	KRT13 DST KRT25 KRT28	4.21e-04	193	37	4	int:KRT5
Cytoband	2q11.1	TRIM43B TRIM43	2.36e-04	28	37	2	2q11.1
Cytoband	17q21.2	KRT25 KRT28	1.47e-03	70	37	2	17q21.2
Cytoband	Ensembl 112 genes in cytogenetic band chr17q12	TADA2A LASP1	6.47e-03	149	37	2	chr17q12
Cytoband	Ensembl 112 genes in cytogenetic band chr17q21	KRT13 KRT25 KRT28	6.51e-03	473	37	3	chr17q21
Cytoband	Ensembl 112 genes in cytogenetic band chr2q11	TRIM43B TRIM43	6.81e-03	153	37	2	chr2q11
GeneFamily	Keratins, type I	KRT13 KRT25 KRT28	4.34e-06	28	21	3	608
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM43B TRIM43	5.38e-03	95	21	2	59
GeneFamily	EF-hand domain containing	CALB2 DST	2.64e-02	219	21	2	863
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-Tuft-related\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GNAT3 CYP1A1 KRT13 MATK ARHGEF10L	4.36e-07	185	37	5	01d0e848d8ede2745cfb10b070e2d9674ef4d477
Drug	Ethambutol dihydrochloride [1070-11-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A	PPIL2 TADA2A GNAS ZNF839 TRIP11 MATK	7.02e-07	196	37	6	4120_DN
Drug	pyrvinium pamoate; Down 200; 1.25uM; MCF7; HT_HG-U133A_EA	MOK CYP1A1 TRIP11 NIPSNAP1 HDLBP	1.35e-05	190	37	5	870_DN
Drug	Chlorprothixene hydrochloride [6469-93-8]; Down 200; 11.4uM; MCF7; HT_HG-U133A	CYP1A1 PPIL2 TADA2A CPT2 ZNF839	1.45e-05	193	37	5	5291_DN
Drug	Promethazine hydrochloride [58-33-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A	CYP1A1 CPT2 MAP3K7 ZMYM5 CEP63	1.57e-05	196	37	5	5317_DN
Drug	Flurandrenolide [1524-88-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A	CYP1A1 PPIL2 TRIP11 DISC1 ZMYM5	1.60e-05	197	37	5	4702_DN
Drug	Iopromide [73334-07-3]; Down 200; 5uM; MCF7; HT_HG-U133A	KRT13 TADA2A ZNF839 DISC1 MATK	1.68e-05	199	37	5	3481_DN
Drug	Folinic acid calcium salt [6035-45-6]; Down 200; 7.8uM; MCF7; HT_HG-U133A	MOK CYP1A1 KRT13 TADA2A MATK	1.73e-05	200	37	5	3442_DN
Disease	cognitive decline measurement	CWF19L2 LASP1 NALCN MAP3K7 KRT25 KRT28	2.48e-05	486	36	6	EFO_0007710
Disease	McCune Albright syndrome (implicated_via_orthology)	GNAT3 GNAT2	4.03e-05	8	36	2	DOID:1858 (implicated_via_orthology)
Disease	Severe Congenital Microcephaly	BUB1B CEP63	6.58e-04	31	36	2	C3853041
Disease	Microlissencephaly	BUB1B CEP63	7.46e-04	33	36	2	C1956147
Disease	dilated cardiomyopathy (is_marker_for)	CYP1A1 MAP3K7	1.04e-03	39	36	2	DOID:12930 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
QQASEEKKEKMMYCK	BUB1B	386	O60566
DMQELKHKYDCKMTQ	ARHGEF10L	231	Q9HCE6
KHKYDCKMTQLMKAA	ARHGEF10L	236	Q9HCE6
FSKDAMMKEKHLYDI	FAM186B	86	Q8IYM0
ENTMKYMETLKNKLC	DISC1	666	Q9NRI5
MMVECSKYHGQLTKE	CPT2	531	P23786
AFMAAQKCHKKNMKD	ESRP1	501	Q6NXG1
MGKRQHQKDKMYITC	PPIL2	1	Q13356
FMQKMVKEHYKTFEK	CYP1A1	261	P04798
MTYLKKNHEEEMKAL	KRT28	221	Q7Z3Y7
NLKKEDKEIYSHMTC	GNAT3	311	A8MTJ3
FCNLMDMVEHYSKDK	MATK	186	P42679
IEMKQSKMDECQKYA	DST	1341	Q03001
EMMEQNCAHSKKKLS	FANCM	1651	Q8IYD8
LAYMKKNHEEEMKEF	KRT13	236	P13646
HCETCKMTLNMKNYK	LASP1	31	Q14847
CIFLETNMSMKKQYH	CWF19L2	751	Q2TBE0
AVFEQHCKMAQEYMK	MAP3K7	521	O43318
HCKMAQEYMKVQTEI	MAP3K7	526	O43318
SEEMTYLKKNHKEEM	KRT25	211	Q7Z3Z0
SEKKIMHYMYQLCKS	MOK	101	Q9UQ07
ENKKEYVHLVCQMRM	HUWE1	4201	Q7Z6Z7
EMTMEYKQELKKLHE	CEP63	91	Q96MT8
KKMEPYDDHSNMEEK	HAUS6	216	Q7Z4H7
EKMKEFMQKYDKNSD	CALB2	66	P22676
HIETMAKLEKMYQDK	FAM161A	106	Q3B820
MDCMNKLKNNKEYLE	NIPSNAP1	136	Q9BPW8
DMHYAKISSMENKAK	RGSL1	311	A5PLK6
QKSKHLKEMYQELME	TRIM43	221	Q96BQ3
QMCTKTKEECEKHYM	TADA2A	101	O75478
KQLQDEKMGYMCTHR	GNAS	671	Q5JWF2
NMRKDVKEIYSHMTC	GNAT2	311	P19087
EELHKMVKKMCQDYL	ZNF839	406	A8K0R7
CINEYKQMMETKSKK	ZMYM5	411	Q9UJ78
KTEYHKMMDIVAAKE	TRIP11	1116	Q15643
QKSKHLKEMYQELME	TRIM43B	221	A6NCK2
NEVEKCTKYMQKMVA	HDLBP	561	Q00341
KKHMENCKQEMFTCH	ZNF512	186	Q96ME7
DKDKLLFKHMCYEME	NALCN	1506	Q8IZF0