Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	N,N-dimethylaniline monooxygenase activity	FMO3 FMO4 FMO6P	6.24e-07	6	64	3	GO:0004499
GeneOntologyMolecularFunction	purine ribonucleotide transmembrane transporter activity	SLC25A5 SLC25A6 ABCD1	5.31e-05	23	64	3	GO:0005346
GeneOntologyMolecularFunction	adenine nucleotide transmembrane transporter activity	SLC25A5 SLC25A6 ABCD1	7.75e-05	26	64	3	GO:0000295
GeneOntologyMolecularFunction	hypotaurine monooxygenase activity	FMO3 FMO4	1.01e-04	5	64	2	GO:0047822
GeneOntologyMolecularFunction	ATP:ADP antiporter activity	SLC25A5 SLC25A6	1.01e-04	5	64	2	GO:0005471
GeneOntologyMolecularFunction	purine nucleotide transmembrane transporter activity	SLC25A5 SLC25A6 ABCD1	1.08e-04	29	64	3	GO:0015216
GeneOntologyMolecularFunction	nucleotide transmembrane transporter activity	SLC25A5 SLC25A6 ABCD1	1.60e-04	33	64	3	GO:0015215
GeneOntologyMolecularFunction	gamma-tubulin binding	RAB11FIP5 BRSK1 DDX3X	2.45e-04	38	64	3	GO:0043015
GeneOntologyMolecularFunction	organophosphate ester transmembrane transporter activity	SLC25A5 SLC25A6 ABCD1	2.64e-04	39	64	3	GO:0015605
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	FMO3 FMO4 FMO6P	2.85e-04	40	64	3	GO:0016709
GeneOntologyMolecularFunction	ADP transmembrane transporter activity	SLC25A5 SLC25A6	5.46e-04	11	64	2	GO:0015217
GeneOntologyMolecularFunction	ATP transmembrane transporter activity	SLC25A5 SLC25A6	8.98e-04	14	64	2	GO:0005347
GeneOntologyMolecularFunction	carbohydrate derivative transmembrane transporter activity	SLC25A5 SLC25A6 ABCD1	8.98e-04	59	64	3	GO:1901505
GeneOntologyMolecularFunction	nucleobase-containing compound transmembrane transporter activity	SLC25A5 SLC25A6 ABCD1	8.98e-04	59	64	3	GO:0015932
GeneOntologyMolecularFunction	ATP hydrolysis activity	RNF213 ABCD1 MTREX CARNS1 DYNC1H1 DDX3X	2.85e-03	441	64	6	GO:0016887
GeneOntologyMolecularFunction	ATP-dependent activity	MYO1F RNF213 ABCD1 MTREX CARNS1 DYNC1H1 DDX3X	3.42e-03	614	64	7	GO:0140657
GeneOntologyBiologicalProcess	negative regulation of epidermal growth factor-activated receptor activity	SOCS4 CBL CBLB	1.20e-05	15	63	3	GO:0007175
GeneOntologyBiologicalProcess	regulation of epidermal growth factor-activated receptor activity	SOCS4 CBL CBLB	4.01e-05	22	63	3	GO:0007176
GeneOntologyBiologicalProcess	regulation of platelet-derived growth factor receptor-alpha signaling pathway	CBL CBLB	9.13e-05	5	63	2	GO:2000583
GeneOntologyBiologicalProcess	mitochondrial ADP transmembrane transport	SLC25A5 SLC25A6	9.13e-05	5	63	2	GO:0140021
GeneOntologyBiologicalProcess	negative regulation of protein tyrosine kinase activity	SOCS4 CBL CBLB	1.04e-04	30	63	3	GO:0061099
GeneOntologyBiologicalProcess	negative regulation of epidermal growth factor receptor signaling pathway	SOCS4 CBL CBLB	1.26e-04	32	63	3	GO:0042059
GeneOntologyBiologicalProcess	negative regulation of signaling receptor activity	SOCS4 CBL CBLB	1.39e-04	33	63	3	GO:2000272
GeneOntologyBiologicalProcess	regulation of vesicle-mediated transport	MCTP1 KCNH1 SYNE1 TMIGD3 LRPAP1 CBL CBLB TBC1D20 NCKAP1L	1.82e-04	667	63	9	GO:0060627
GeneOntologyBiologicalProcess	endocytosis	MCTP1 SYNE1 MYO1F RAB11FIP5 LRPAP1 NCF2 CBL CBLB TBC1D24 NCKAP1L	1.89e-04	827	63	10	GO:0006897
GeneOntologyBiologicalProcess	platelet-derived growth factor receptor-alpha signaling pathway	CBL CBLB	1.91e-04	7	63	2	GO:0035790
GeneOntologyBiologicalProcess	negative regulation of ERBB signaling pathway	SOCS4 CBL CBLB	1.96e-04	37	63	3	GO:1901185
GeneOntologyBiologicalProcess	purine ribonucleotide transport	SLC25A5 SLC25A6 ABCD1	2.48e-04	40	63	3	GO:0015868
GeneOntologyBiologicalProcess	mitochondrial ATP transmembrane transport	SLC25A5 SLC25A6	2.54e-04	8	63	2	GO:1990544
GeneOntologyBiologicalProcess	regulated exocytosis	KCNH1 MYO1F TMIGD3 RAB11FIP5 CBL NCKAP1L	2.59e-04	291	63	6	GO:0045055
GeneOntologyBiologicalProcess	adenine nucleotide transport	SLC25A5 SLC25A6 ABCD1	2.86e-04	42	63	3	GO:0051503
GeneOntologyBiologicalProcess	purine nucleotide transport	SLC25A5 SLC25A6 ABCD1	3.29e-04	44	63	3	GO:0015865
GeneOntologyBiologicalProcess	leukocyte degranulation	MYO1F TMIGD3 CBL NCKAP1L	3.34e-04	108	63	4	GO:0043299
GeneOntologyBiologicalProcess	regulation of response to oxidative stress	MCTP1 ABCD1 TBC1D24	4.00e-04	47	63	3	GO:1902882
GeneOntologyBiologicalProcess	vesicle-mediated transport in synapse	KCNH1 SYNE1 RAB11FIP5 BRSK1 CBLB TBC1D24	4.37e-04	321	63	6	GO:0099003
GeneOntologyBiologicalProcess	nucleotide transport	SLC25A5 SLC25A6 ABCD1	4.80e-04	50	63	3	GO:0006862
GeneOntologyBiologicalProcess	postsynaptic endocytosis	SYNE1 RAB11FIP5 CBLB	5.09e-04	51	63	3	GO:0140239
GeneOntologyBiologicalProcess	postsynaptic neurotransmitter receptor internalization	SYNE1 RAB11FIP5 CBLB	5.09e-04	51	63	3	GO:0098884
GeneOntologyBiologicalProcess	ADP transport	SLC25A5 SLC25A6	5.94e-04	12	63	2	GO:0015866
GeneOntologyCellularComponent	organelle envelope	DST RAE1 SLC25A5 SLC25A6 TRIAP1 KCNH1 SYNE1 GUCY2D MRPS27 DISP3 RAB11FIP5 ABCD1 RETSAT DYNC1H1 SLC3A1 TBC1D20	5.82e-06	1435	65	16	GO:0031967
GeneOntologyCellularComponent	nuclear envelope	DST RAE1 KCNH1 SYNE1 GUCY2D DISP3 RETSAT DYNC1H1 TBC1D20	5.60e-05	560	65	9	GO:0005635
GeneOntologyCellularComponent	nuclear outer membrane	SYNE1 GUCY2D RETSAT	2.61e-04	40	65	3	GO:0005640
Domain	-	EWSR1 TAF15 FUS	4.32e-06	10	63	3	4.10.1060.10
Domain	Adaptor_Cbl_EF_hand-like	CBL CBLB	3.35e-05	3	63	2	IPR014741
Domain	Adaptor_Cbl_SH2-like	CBL CBLB	3.35e-05	3	63	2	IPR014742
Domain	Cbl_N2	CBL CBLB	3.35e-05	3	63	2	PF02761
Domain	Cbl_N3	CBL CBLB	3.35e-05	3	63	2	PF02762
Domain	Cbl_N	CBL CBLB	3.35e-05	3	63	2	PF02262
Domain	Adaptor_Cbl_N_hlx	CBL CBLB	3.35e-05	3	63	2	IPR003153
Domain	CBL_PTB	CBL CBLB	3.35e-05	3	63	2	PS51506
Domain	Adaptor_Cbl	CBL CBLB	3.35e-05	3	63	2	IPR024162
Domain	Cbl_PTB	CBL CBLB	3.35e-05	3	63	2	IPR024159
Domain	-	CBL CBLB	3.35e-05	3	63	2	1.20.930.20
Domain	zf-RanBP	EWSR1 TAF15 FUS	5.38e-05	22	63	3	PF00641
Domain	ZnF_RBZ	EWSR1 TAF15 FUS	6.17e-05	23	63	3	SM00547
Domain	ZF_RANBP2_2	EWSR1 TAF15 FUS	6.17e-05	23	63	3	PS50199
Domain	ZF_RANBP2_1	EWSR1 TAF15 FUS	7.04e-05	24	63	3	PS01358
Domain	Znf_RanBP2	EWSR1 TAF15 FUS	7.98e-05	25	63	3	IPR001876
Domain	FMO-like	FMO3 FMO4	1.11e-04	5	63	2	PF00743
Domain	Flavin_mOase	FMO3 FMO4	1.11e-04	5	63	2	IPR000960
Domain	Flavin_mOase-like	FMO3 FMO4	1.11e-04	5	63	2	IPR020946
Domain	DiMe-aniline_mOase	FMO3 FMO4	1.11e-04	5	63	2	IPR012143
Domain	UBA	BRSK1 CBL CBLB	4.39e-04	44	63	3	IPR015940
Domain	UBA	BRSK1 CBL CBLB	5.34e-04	47	63	3	PS50030
Domain	Mit_uncoupling	SLC25A5 SLC25A6	7.23e-04	12	63	2	IPR002030
Domain	-	FMO3 FMO4 RETSAT	8.93e-04	56	63	3	3.50.50.60
Domain	FAD/NAD-binding_dom	FMO3 FMO4 RETSAT	9.40e-04	57	63	3	IPR023753
Domain	C2	MCTP1 PIK3C2B RAB11FIP5 PLCB4	1.00e-03	131	63	4	PF00168
Domain	C2	MCTP1 PIK3C2B RAB11FIP5 PLCB4	1.18e-03	137	63	4	SM00239
Domain	C2	MCTP1 PIK3C2B RAB11FIP5 PLCB4	1.35e-03	142	63	4	PS50004
Domain	-	MCTP1 PIK3C2B RAB11FIP5 PLCB4	1.57e-03	148	63	4	2.60.40.150
Domain	C2_dom	MCTP1 PIK3C2B RAB11FIP5 PLCB4	2.28e-03	164	63	4	IPR000008
Domain	SH3_1	DST SH3TC1 MYO1F NCF2	2.28e-03	164	63	4	PF00018
Domain	Actinin_actin-bd_CS	DST SYNE1	2.71e-03	23	63	2	IPR001589
Domain	Spectrin	DST SYNE1	2.71e-03	23	63	2	PF00435
Domain	ACTININ_2	DST SYNE1	2.71e-03	23	63	2	PS00020
Domain	ACTININ_1	DST SYNE1	2.71e-03	23	63	2	PS00019
Domain	Aden_trnslctor	SLC25A5 SLC25A6	4.00e-03	28	63	2	IPR002113
Domain	Spectrin_repeat	DST SYNE1	4.29e-03	29	63	2	IPR002017
Domain	UBA	CBL CBLB	4.58e-03	30	63	2	SM00165
Domain	Spectrin/alpha-actinin	DST SYNE1	5.20e-03	32	63	2	IPR018159
Domain	Mit_carrier	SLC25A5 SLC25A6	5.20e-03	32	63	2	IPR002067
Domain	SPEC	DST SYNE1	5.20e-03	32	63	2	SM00150
Domain	SH3	DST SH3TC1 MYO1F NCF2	6.08e-03	216	63	4	PS50002
Domain	SH2	SOCS4 CBL CBLB	6.26e-03	111	63	3	PS50001
Domain	SH2	SOCS4 CBL CBLB	6.42e-03	112	63	3	IPR000980
Domain	-	SOCS4 CBL CBLB	6.42e-03	112	63	3	3.30.505.10
Domain	SH3_domain	DST SH3TC1 MYO1F NCF2	6.49e-03	220	63	4	IPR001452
Domain	UBA	CBL CBLB	6.55e-03	36	63	2	PF00627
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABBERANT_ATXN2_3_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	SLC25A5 SLC25A6 PLCB4	4.40e-05	18	55	3	M47659
Pathway	KEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY	SLC25A5 SLC25A6 PLCB4	6.11e-05	20	55	3	M47688
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY	SLC25A5 SLC25A6 PLCB4	7.11e-05	21	55	3	M47689
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	SLC25A5 SLC25A6 PLCB4	8.21e-05	22	55	3	M47690
Pathway	KEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY	SLC25A5 SLC25A6 PLCB4	8.21e-05	22	55	3	M47675
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	SLC25A5 SLC25A6 PLCB4	9.42e-05	23	55	3	M47676
Pathway	WP_CATALYTIC_CYCLE_OF_MAMMALIAN_FLAVINCONTAINING_MONOOXYGENASES_FMOS	FMO3 FMO4	1.48e-04	5	55	2	M39449
Pathway	REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS	RAE1 SLC25A5 SLC25A6	3.98e-04	37	55	3	M1029
Pubmed	The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response.	EWSR1 TAF15 FUS	6.23e-09	3	65	3	18620564
Pubmed	mRNA and protein levels of FUS, EWSR1, and TAF15 are upregulated in liposarcoma.	EWSR1 TAF15 FUS	6.23e-09	3	65	3	21344536
Pubmed	A conserved N-terminal motif is required for complex formation between FUS, EWSR1, TAF15 and their oncogenic fusion proteins.	EWSR1 TAF15 FUS	6.23e-09	3	65	3	23975937
Pubmed	Aggregation of FET Proteins as a Pathological Change in Amyotrophic Lateral Sclerosis.	EWSR1 TAF15 FUS	6.23e-09	3	65	3	27311318
Pubmed	FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations.	EWSR1 TAF15 FUS	6.23e-09	3	65	3	21856723
Pubmed	Role of FET proteins in neurodegenerative disorders.	EWSR1 TAF15 FUS	6.23e-09	3	65	3	27415968
Pubmed	O-GlcNAc glycosylation stoichiometry of the FET protein family: only EWS is glycosylated with a high stoichiometry.	EWSR1 TAF15 FUS	6.23e-09	3	65	3	27903134
Pubmed	Characterization of a new brain-specific isoform of the EWS oncoprotein.	EWSR1 TAF15 FUS	6.23e-09	3	65	3	11422378
Pubmed	Gene expression responses to FUS, EWS, and TAF15 reduction and stress granule sequestration analyses identifies FET-protein non-redundant functions.	EWSR1 TAF15 FUS	6.23e-09	3	65	3	23049996
Pubmed	Post-transcriptional regulation of FUS and EWS protein expression by miR-141 during neural differentiation.	EWSR1 TAF15 FUS	2.49e-08	4	65	3	28453628
Pubmed	The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex.	EWSR1 TAF15 FUS	2.49e-08	4	65	3	30398641
Pubmed	The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcription.	EWSR1 TAF15 FUS	2.49e-08	4	65	3	9660765
Pubmed	Charting the molecular network of the drug target Bcr-Abl.	SLC25A5 SLC25A6 PIK3C2B FUS CBL CBLB DYNC1H1 DDX3X	3.65e-08	266	65	8	19380743
Pubmed	Identification of proteins interacting with protein arginine methyltransferase 8: the Ewing sarcoma (EWS) protein binds independent of its methylation state.	EWSR1 TAF15 FUS DDX3X	9.58e-08	23	65	4	18320585
Pubmed	Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription.	EWSR1 TAF15 FUS	1.24e-07	6	65	3	18509338
Pubmed	Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans.	FMO3 FMO4 FMO6P	1.24e-07	6	65	3	12527699
Pubmed	The hnRNP RALY regulates PRMT1 expression and interacts with the ALS-linked protein FUS: implication for reciprocal cellular localization.	EWSR1 TAF15 FUS	1.24e-07	6	65	3	30354839
Pubmed	Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis.	SLC25A5 SLC25A6 MRPS27 EWSR1 FUS BRSK1 DDX3X	3.02e-07	236	65	7	36339263
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	DFFA RAB11FIP5 EWSR1 TAF15 CBL DYNC1H1 RGS12	5.08e-07	255	65	7	15324660
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	SLC25A5 SLC25A6 TSEN34 RNF213 TAF15 DYNC1H1 DDX3X	6.41e-07	264	65	7	32814769
Pubmed	TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules.	EWSR1 FUS DDX3X	7.41e-07	10	65	3	18632687
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	SLC25A5 SLC25A6 TSEN34 MRPS27 EWSR1 TAF15 FUS MTREX DYNC1H1 DDX3X ZNF287 TGS1	1.33e-06	1153	65	12	29845934
Pubmed	Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.	SLC25A5 SLC25A6 PIK3C2B CBL CBLB	1.48e-06	103	65	5	21706016
Pubmed	A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded Vpx.	SLC25A5 TAF15 FUS DDX3X	1.56e-06	45	65	4	30619335
Pubmed	ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center.	EWSR1 TAF15 FUS DDX3X	1.71e-06	46	65	4	20890123
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	DST SLC25A5 SLC25A6 SYNE1 EWSR1 ALDH1L1 FUS BRSK1 DYNC1H1 DDX3X	2.42e-06	807	65	10	30575818
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	DST RAE1 SLC25A5 SLC25A6 SYNE1 EWSR1 TAF15 FUS MTREX DYNC1H1 DDX3X	2.86e-06	1024	65	11	24711643
Pubmed	Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA-splicing factors during adipogenesis.	SLC25A5 EWSR1 TAF15 FUS DDX3X	3.41e-06	122	65	5	29530978
Pubmed	Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis.	EWSR1 TAF15	3.44e-06	2	65	2	22454397
Pubmed	Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy.	CBL CBLB	3.44e-06	2	65	2	25871390
Pubmed	Expression patterns of the human sarcoma-associated genes FUS and EWS and the genomic structure of FUS.	EWSR1 FUS	3.44e-06	2	65	2	8921363
Pubmed	EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functions.	EWSR1 FUS	3.44e-06	2	65	2	26573619
Pubmed	Genomic structure of the human RBP56/hTAFII68 and FUS/TLS genes.	TAF15 FUS	3.44e-06	2	65	2	9795213
Pubmed	Changes in the expression of the human adenine nucleotide translocase isoforms condition cellular metabolic/proliferative status.	SLC25A5 SLC25A6	3.44e-06	2	65	2	26842067
Pubmed	Cbl-b is a negative regulator of inflammatory cytokines produced by IgE-activated mast cells.	CBL CBLB	3.44e-06	2	65	2	17056522
Pubmed	Cloning and mapping of a human RBP56 gene encoding a putative RNA binding protein similar to FUS/TLS and EWS proteins.	EWSR1 TAF15	3.44e-06	2	65	2	8954779
Pubmed	Association of a new c-Cbl related protein with the very first stages of apoptosis induction.	CBL CBLB	3.44e-06	2	65	2	12102152
Pubmed	Cbl and Cbl-b control the germinal center reaction by facilitating naive B cell antigen processing.	CBL CBLB	3.44e-06	2	65	2	32584413
Pubmed	A novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells.	CBL CBLB	3.44e-06	2	65	2	27276677
Pubmed	Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia.	CBL CBLB	3.44e-06	2	65	2	17475912
Pubmed	Fasudil, a clinically safe ROCK inhibitor, decreases disease burden in a Cbl/Cbl-b deficiency-driven murine model of myeloproliferative disorders.	CBL CBLB	3.44e-06	2	65	2	26177294
Pubmed	The role of E3 ubiquitin ligase Cbl proteins in β-elemene reversing multi-drug resistance of human gastric adenocarcinoma cells.	CBL CBLB	3.44e-06	2	65	2	23665906
Pubmed	Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomy.	CBL CBLB	3.44e-06	2	65	2	24994594
Pubmed	Ubiquitin ligase gene expression in healthy volunteers with 20-day bedrest.	FBXO32 CBLB	3.44e-06	2	65	2	16868939
Pubmed	A morphologic and molecular reappraisal of myoepithelial tumors of soft tissue, bone, and viscera with EWSR1 and FUS gene rearrangements.	EWSR1 FUS	3.44e-06	2	65	2	31994243
Pubmed	c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation.	CBL CBLB	3.44e-06	2	65	2	12415267
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	DST SLC25A5 SLC25A6 SYNE1 RNF213 EWSR1 TAF15 FUS DYNC1H1 DDX3X	3.60e-06	844	65	10	25963833
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	RAE1 SLC25A5 SLC25A6 MRPS27 EWSR1 TAF15 FUS MTREX CBLB DDX3X	3.71e-06	847	65	10	35850772
Pubmed	Identification of 14-3-3epsilon substrates from embryonic murine brain.	SLC25A5 EWSR1 FUS BRSK1 CBL	5.02e-06	132	65	5	16944949
Pubmed	Landscape of the SOX2 protein-protein interactome.	SLC25A5 EWSR1 TAF15 FUS DDX3X	5.81e-06	136	65	5	21280222
Pubmed	Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.	PIK3C2B CBL CBLB	5.91e-06	19	65	3	31959764
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	SLC25A5 EWSR1 TAF15 FUS MTREX DDX3X	6.55e-06	244	65	6	29884807
Pubmed	Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1.	SLC25A5 SLC25A6 RAB11FIP5 DDX3X	6.90e-06	65	65	4	18729074
Pubmed	Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms.	RAE1 SLC25A5 SLC25A6 MRPS27 EWSR1 FUS	8.61e-06	256	65	6	24189400
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	DST SLC25A5 SLC25A6 SYNE1 RAB11FIP5 EWSR1 FUS DYNC1H1 DDX3X FAM111B	1.00e-05	949	65	10	36574265
Pubmed	Expression of c-Cbl, Cbl-b, and epidermal growth factor receptor in gastric carcinoma and their clinical significance.	CBL CBLB	1.03e-05	3	65	2	20038312
Pubmed	Regulation of immune responses by E3 ubiquitin-protein ligases.	CBL CBLB	1.03e-05	3	65	2	11826757
Pubmed	FUS-NFATC2 or EWSR1-NFATC2 Fusions Are Present in a Large Proportion of Simple Bone Cysts.	EWSR1 FUS	1.03e-05	3	65	2	32991339
Pubmed	Selective interactions of hnRNP M isoforms with the TET proteins TAF15 and TLS/FUS.	TAF15 FUS	1.03e-05	3	65	2	24474660
Pubmed	Cbl-b regulates the CD28 dependence of T-cell activation.	CBL CBLB	1.03e-05	3	65	2	10646609
Pubmed	Cbl-b and c-Cbl negatively regulate osteoblast differentiation by enhancing ubiquitination and degradation of Osterix.	CBL CBLB	1.03e-05	3	65	2	25744063
Pubmed	A direct interaction between the adaptor protein Cbl-b and the kinase zap-70 induces a positive signal in T cells.	CBL CBLB	1.03e-05	3	65	2	10074432
Pubmed	E3 ubiquitin ligases Cbl-b and c-Cbl downregulate PD-L1 in EGFR wild-type non-small cell lung cancer.	CBL CBLB	1.03e-05	3	65	2	29364514
Pubmed	NCF2, MYO1F, S1PR4, and FCN1 as potential noninvasive diagnostic biomarkers in patients with obstructive coronary artery: A weighted gene co-expression network analysis.	MYO1F NCF2	1.03e-05	3	65	2	31245869
Pubmed	Quantification and cellular localization of expression in human skin of genes encoding flavin-containing monooxygenases and cytochromes P450.	FMO3 FMO4	1.03e-05	3	65	2	11551524
Pubmed	Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors.	CBL CBLB	1.03e-05	3	65	2	12874286
Pubmed	Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells.	CBL CBLB	1.03e-05	3	65	2	31282857
Pubmed	Recurrent rearrangement of the Ewing's sarcoma gene, EWSR1, or its homologue, TAF15, with the transcription factor CIZ/NMP4 in acute leukemia.	EWSR1 TAF15	1.03e-05	3	65	2	12359745
Pubmed	Differential ubiquitin binding of the UBA domains from human c-Cbl and Cbl-b: NMR structural and biochemical insights.	CBL CBLB	1.03e-05	3	65	2	18596201
Pubmed	Inactivation of c-Cbl or Cbl-b differentially affects signaling from the high affinity IgE receptor.	CBL CBLB	1.03e-05	3	65	2	15265912
Pubmed	[Expressions of c-Cbl, Cbl-b and EGFR and its role of prognosis in NSCLC].	CBL CBLB	1.03e-05	3	65	2	21645455
Pubmed	Ubiquitin Ligases CBL and CBL-B Maintain the Homeostasis and Immune Quiescence of Dendritic Cells.	CBL CBLB	1.03e-05	3	65	2	34630435
Pubmed	T-cell receptor ligation causes Wiskott-Aldrich syndrome protein degradation and F-actin assembly downregulation.	CBL CBLB	1.03e-05	3	65	2	23684068
Pubmed	A Subset of Malignant Mesotheliomas in Young Adults Are Associated With Recurrent EWSR1/FUS-ATF1 Fusions.	EWSR1 FUS	1.03e-05	3	65	2	28505004
Pubmed	Cbl regulates the activity of SIRT2.	CBL CBLB	1.03e-05	3	65	2	25285640
Pubmed	VAV1-Cre mediated hematopoietic deletion of CBL and CBL-B leads to JMML-like aggressive early-neonatal myeloproliferative disease.	CBL CBLB	1.03e-05	3	65	2	27449297
Pubmed	The human mitochondrial ADP/ATP carriers: kinetic properties and biogenesis of wild-type and mutant proteins in the yeast S. cerevisiae.	SLC25A5 SLC25A6	1.03e-05	3	65	2	12450408
Pubmed	Unclassified low grade spindle cell sarcoma with storiform pattern characterized by recurrent novel EWSR1/FUS-NACC1 fusions.	EWSR1 FUS	1.03e-05	3	65	2	33859361
Pubmed	Novel FUS-KLF17 and EWSR1-KLF17 fusions in myoepithelial tumors.	EWSR1 FUS	1.03e-05	3	65	2	25706482
Pubmed	Cbl and Cbl-b independently regulate EGFR through distinct receptor interaction modes.	CBL CBLB	1.03e-05	3	65	2	37903221
Pubmed	NR4A3 fusion proteins trigger an axon guidance switch that marks the difference between EWSR1 and TAF15 translocated extraskeletal myxoid chondrosarcomas.	EWSR1 TAF15	1.03e-05	3	65	2	31020999
Pubmed	Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American.	FMO3 FMO6P	1.03e-05	3	65	2	28413702
Pubmed	Ewing sarcoma with ERG gene rearrangements: A molecular study focusing on the prevalence of FUS-ERG and common pitfalls in detecting EWSR1-ERG fusions by FISH.	EWSR1 FUS	1.03e-05	3	65	2	26690869
Pubmed	Novel insights into the mechanisms of CIN85 SH3 domains binding to Cbl proteins: solution-based investigations and in vivo implications.	CBL CBLB	1.03e-05	3	65	2	19268472
Pubmed	Cbl negatively regulates JNK activation and cell death.	CBL CBLB	1.03e-05	3	65	2	19546888
Pubmed	The tyrosine phosphatase SHP-2 regulates differentiation and apoptosis of individual primary T lymphocytes.	CBL CBLB	1.03e-05	3	65	2	17330819
Pubmed	A tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulation.	CBL CBLB	1.03e-05	3	65	2	18316398
Pubmed	DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase.	SLC25A5 SLC25A6	1.03e-05	3	65	2	2541251
Pubmed	Cytokeratin-positive Malignant Tumor in the Abdomen With EWSR1/FUS-CREB Fusion: A Clinicopathologic Study of 8 Cases.	EWSR1 FUS	1.03e-05	3	65	2	34049318
Pubmed	Two distinct genes for ADP/ATP translocase are expressed at the mRNA level in adult human liver.	SLC25A5 SLC25A6	1.03e-05	3	65	2	2829183
Pubmed	c-Cbl and Cbl-b ligases mediate 17-allylaminodemethoxygeldanamycin-induced degradation of autophosphorylated Flt3 kinase with internal tandem duplication through the ubiquitin proteasome pathway.	CBL CBLB	1.03e-05	3	65	2	21768087
Pubmed	Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions.	EWSR1 FUS	1.03e-05	3	65	2	38168093
Pubmed	Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS.	TAF15 FUS	1.03e-05	3	65	2	27460707
Pubmed	Regulation of stem cell factor receptor signaling by Cbl family proteins (Cbl-b/c-Cbl).	CBL CBLB	1.03e-05	3	65	2	15315962
Pubmed	The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling.	CBL CBLB	1.03e-05	3	65	2	27048651
Pubmed	Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b.	CBL CBLB	1.03e-05	3	65	2	15273720
Pubmed	Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells.	CBL CBLB	1.03e-05	3	65	2	11087752
Pubmed	The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into macropinosomes.	CBL CBLB	1.03e-05	3	65	2	38170572
Pubmed	FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.	EWSR1 TAF15 FUS	1.07e-05	23	65	3	30962207
Pubmed	Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.	SLC25A5 SLC25A6 EWSR1 ALDH1L1 FUS DDX3X	1.14e-05	269	65	6	30442662
Interaction	YWHAZ interactions	DFFA DST MCTP1 RAE1 RPS6KA5 PIK3C2B RAB11FIP5 EWSR1 FUS FBXO32 MTREX BRD1 CBL DYNC1H1 RGS12 SLC3A1	1.27e-06	1319	61	16	int:YWHAZ
Interaction	MYCBP2 interactions	DST RAE1 EWSR1 TAF15 FUS DYNC1H1 RGS12 DDX3X	1.12e-05	355	61	8	int:MYCBP2
Interaction	ITSN1 interactions	DST RPS6KA5 PIK3C2B SYNE1 CBL CBLB DYNC1H1	1.29e-05	259	61	7	int:ITSN1
Interaction	SAP30BP interactions	EWSR1 TAF15 FUS FBXO32 DYNC1H1	1.65e-05	105	61	5	int:SAP30BP
Interaction	YWHAE interactions	DST ACD SLC25A5 SLC25A6 PIK3C2B RAB11FIP5 EWSR1 FUS MTREX BRD1 BRSK1 CBL DYNC1H1 RGS12	1.76e-05	1256	61	14	int:YWHAE
Interaction	TARDBP interactions	SLC25A5 MRPS27 LRPAP1 NCF2 EWSR1 TAF15 FUS MTREX DDX3X	2.49e-05	520	61	9	int:TARDBP
Interaction	BMI1 interactions	DST SLC25A5 SYNE1 RAB11FIP5 EWSR1 TAF15 FUS MTREX CBL DYNC1H1	2.61e-05	659	61	10	int:BMI1
Interaction	RNU1-1 interactions	EWSR1 TAF15 FUS	3.38e-05	21	61	3	int:RNU1-1
Interaction	MEPCE interactions	SLC25A5 SLC25A6 MRPS27 LRPAP1 EWSR1 TAF15 FUS MTREX DYNC1H1 DDX3X ZNF287	4.70e-05	859	61	11	int:MEPCE
Interaction	OBSL1 interactions	DST RAE1 SLC25A5 SYNE1 EWSR1 TAF15 FUS MTREX CBLB DYNC1H1 DDX3X	7.29e-05	902	61	11	int:OBSL1
Interaction	TERF2 interactions	DST ACD SYNE1 ABCD1 MTREX TEP1 DDX3X	7.30e-05	340	61	7	int:TERF2
Interaction	YWHAG interactions	DFFA DST PIK3C2B RAB11FIP5 EWSR1 TAF15 FBXO32 MTREX BRD1 CBL DYNC1H1 RGS12 DDX3X	7.46e-05	1248	61	13	int:YWHAG
Interaction	NUMA1 interactions	RAE1 LRPAP1 EWSR1 TAF15 FUS BRD1 DYNC1H1 PRDM2	8.09e-05	469	61	8	int:NUMA1
Interaction	MAPT interactions	SLC25A5 RPS6KA5 SLC25A6 MRPS27 LRPAP1 EWSR1 TAF15 ALDH1L1 FUS BRSK1 DYNC1H1 DDX3X	1.12e-04	1119	61	12	int:MAPT
Interaction	ZFYVE21 interactions	EWSR1 TAF15 FUS DDX3X	1.22e-04	84	61	4	int:ZFYVE21
Interaction	USP7 interactions	GPRASP1 DST RAE1 ACD SYNE1 HHAT MYO1F EWSR1 ABCD1 ALDH1L1 MTREX DYNC1H1 DDX3X	1.25e-04	1313	61	13	int:USP7
Interaction	ARAF interactions	SLC25A5 SLC25A6 EWSR1 TAF15 FUS BRD1 RGS12	1.37e-04	376	61	7	int:ARAF
Interaction	CUL7 interactions	RAE1 SLC25A5 KCNH1 EWSR1 TAF15 FUS MTREX BRD1 DYNC1H1 DDX3X	2.06e-04	845	61	10	int:CUL7
Interaction	USP11 interactions	RAE1 TAF15 ALDH1L1 FBXO32 MTREX BRD1 DYNC1H1 DDX3X	2.10e-04	539	61	8	int:USP11
Interaction	COPS6 interactions	RAE1 SLC25A5 EWSR1 TAF15 FUS FBXO32 DDX3X	2.25e-04	408	61	7	int:COPS6
Interaction	TAF15 interactions	SLC25A5 EWSR1 TAF15 FUS FBXO32 MTREX DDX3X	2.25e-04	408	61	7	int:TAF15
Interaction	METTL3 interactions	KCNH1 TSEN34 EWSR1 FUS FBXO32 DDX3X	2.28e-04	287	61	6	int:METTL3
Interaction	USP15 interactions	DFFA RAE1 SLC25A5 RNF213 TAF15 FUS DYNC1H1 DDX3X	2.30e-04	546	61	8	int:USP15
Interaction	SNRPD2 interactions	RNF213 EWSR1 TAF15 FUS MTREX DYNC1H1 TGS1	2.46e-04	414	61	7	int:SNRPD2
Interaction	CUL1 interactions	RAE1 SLC25A5 SLC25A6 MRPS27 EWSR1 TAF15 FUS FBXO32 MTREX DDX3X	2.75e-04	876	61	10	int:CUL1
Interaction	PRMT8 interactions	EWSR1 TAF15 FUS DDX3X	2.79e-04	104	61	4	int:PRMT8
Interaction	NUDCD2 interactions	ACD SLC25A5 SLC25A6 SYNE1 FUS DYNC1H1 DDX3X	2.85e-04	424	61	7	int:NUDCD2
Interaction	CUL5 interactions	ACD SLC25A5 SOCS4 LRPAP1 EWSR1 TAF15 FUS DDX3X	2.96e-04	567	61	8	int:CUL5
Interaction	FMO2 interactions	FMO3 FMO4	3.20e-04	9	61	2	int:FMO2
Interaction	WBP4 interactions	SLC25A5 EWSR1 FUS DDX3X	3.33e-04	109	61	4	int:WBP4
Interaction	PSAP interactions	SLC25A5 RAB11FIP5 EWSR1 FUS DDX3X	3.47e-04	200	61	5	int:PSAP
Cytoband	1q24.3	FMO3 FMO4 FMO6P	3.04e-06	20	65	3	1q24.3
Cytoband	Ensembl 112 genes in cytogenetic band chr1q24	FMO3 FMO4 FMO6P	8.34e-04	129	65	3	chr1q24
Cytoband	1q32	PIK3C2B HHAT	2.22e-03	49	65	2	1q32
GeneFamily	Zinc fingers RANBP2-type \|RNA binding motif containing	EWSR1 TAF15 FUS	1.51e-05	21	42	3	89
Coexpression	GSE43863_NAIVE_VS_LY6C_INT_CXCR5POS_CD4_EFF_TCELL_D6_LCMV_UP	GPRASP1 FMO3 RPS6KA5 BRD1 TBC1D24 TGS1	9.54e-06	197	65	6	M9730
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RNF213 FUS CBLB DYNC1H1 DDX3X PRDM2	3.31e-07	188	65	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MCTP1 SH3TC1 MYO1F NCF2 PGBD5 NCKAP1L	4.62e-07	199	65	6	744b63fba33b176ab7dde11646ccb313665505f7
ToppCell	facs-MAT-Fat-3m-Myeloid-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 MYO1F NCF2 TEP1 NCKAP1L	4.19e-06	164	65	5	1250876abd7311f86730e5b9c03c3610cc2ff6d3
ToppCell	facs-MAT-Fat-3m-Myeloid\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 MYO1F NCF2 TEP1 NCKAP1L	4.19e-06	164	65	5	fa0d77b648cde5e42b9394e877168c80de238bde
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	NCF2 EWSR1 MTREX TEP1 NCKAP1L	4.45e-06	166	65	5	063d68f2ffb40770cb4601fa1cb6426ae26f7a37
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	NCF2 EWSR1 MTREX TEP1 NCKAP1L	4.45e-06	166	65	5	417cfb207da08fa1a0fd5f2a13c8786628667a8e
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	NCF2 EWSR1 MTREX TEP1 NCKAP1L	4.45e-06	166	65	5	f28d07715e6b00ca2a0df39273c5f569744be5a8
ToppCell	3'_v3\|World / Manually curated celltypes from each tissue	MYO1F NCF2 FUS BRD1 DDX3X	6.24e-06	178	65	5	42502f14d9c756df8104900ac6484477b885d3d9
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2\|TCGA-Skin / Sample_Type by Project: Shred V9	RPS6KA5 KCNH1 HHAT RETSAT DYNC1H1	6.77e-06	181	65	5	9d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCell	Control-Myeloid\|Control / group, cell type (main and fine annotations)	MCTP1 SH3TC1 MYO1F NCF2 NCKAP1L	8.79e-06	191	65	5	9c4acc5f3c2f9c0c5520863bb22f391774372347
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Artery\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MCTP1 RPS6KA5 PIK3C2B DISP3 PLCB4	8.79e-06	191	65	5	4b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	MCTP1 MYO1F RNF213 FAM111B NCKAP1L	9.01e-06	192	65	5	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 RAB11FIP5 RNF213 FBXO32 CBLB	9.48e-06	194	65	5	e72be6dc2711c1d4f16943c8615cf9dc2e961ff3
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SYNE1 RAB11FIP5 RNF213 FBXO32 CBLB	9.48e-06	194	65	5	ac03be73fdc32dacd4a450c0fb28617e043b8444
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SYNE1 RAB11FIP5 RNF213 FBXO32 CBLB	9.48e-06	194	65	5	7ab4418a8a12c488d74af3676bdac672628da80c
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 RAB11FIP5 RNF213 FBXO32 CBLB	9.48e-06	194	65	5	760761ce7d22edf9a8cec71e8ab0caa273fce3f7
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|lung / Disease (COVID-19 only), tissue and cell type	MCTP1 SH3TC1 MYO1F NCF2 NCKAP1L	9.72e-06	195	65	5	148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCell	COVID-19-Myeloid-Monocytes\|COVID-19 / group, cell type (main and fine annotations)	MCTP1 MYO1F NCF2 CBL NCKAP1L	9.96e-06	196	65	5	04d710267658ea5601ae2cfb4ed5acb8a29bd8a1
ToppCell	Children_(3_yrs)-Immune-monocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MCTP1 SH3TC1 MYO1F CBL NCKAP1L	9.96e-06	196	65	5	cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MCTP1 MYO1F RNF213 NCF2 NCKAP1L	1.02e-05	197	65	5	e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	MYO1F RNF213 EWSR1 FUS DYNC1H1	1.05e-05	198	65	5	61ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCell	Immune-monocyte\|World / Lineage, Cell type, age group and donor	MCTP1 SH3TC1 MYO1F NCF2 NCKAP1L	1.05e-05	198	65	5	d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MCTP1 SH3TC1 MYO1F NCF2 NCKAP1L	1.07e-05	199	65	5	9545ac59c8d75f5747dff86cb511a149dc103b31
ToppCell	(07)_Ionocytes\|World / shred by cell type by condition	SLC25A5 KCNH1 MFSD6L PLCB4 FBXO32	1.07e-05	199	65	5	8194777d367405a7840787e977854b5c07e3bd6b
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MCTP1 SH3TC1 MYO1F NCF2 NCKAP1L	1.07e-05	199	65	5	1413156b7be5373fd02bbe39ec50ccfe165fa6d1
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DST MCTP1 RNF213 PLCB4 DYNC1H1	1.10e-05	200	65	5	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	Tracheal-NucSeq-Immune_Myeloid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MCTP1 SH3TC1 MYO1F NCF2 NCKAP1L	1.10e-05	200	65	5	ad7ae5106141669b353800fece833b3cd5bdccee
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MCTP1 SH3TC1 MYO1F NCF2 NCKAP1L	1.10e-05	200	65	5	f3dc07a7cc8cf041da8fe610d21af595818cf2d8
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DST MCTP1 RNF213 PLCB4 DYNC1H1	1.10e-05	200	65	5	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	Control-Control-Lymphocyte-T/NK-CD8+_Tem\|Control / Disease, condition lineage and cell class	SYNE1 RAB11FIP5 RNF213 FBXO32 CBLB	1.10e-05	200	65	5	fddb3df5b90eb97ef8ed80fac320c1a90903f012
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RNF213 FUS DYNC1H1 DDX3X PRDM2	1.10e-05	200	65	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Monocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MCTP1 MYO1F NCF2 CBL NCKAP1L	1.10e-05	200	65	5	8872d5fa101d413fb43b4231d476878678543035
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MCTP1 MYO1F NCF2 CBL NCKAP1L	1.10e-05	200	65	5	fc061de0db2e8b5ca47f5e2a1e861018e7f1b582
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	RAE1 MYO1F NCF2 CBL	1.35e-05	99	65	4	a815a887094204de30b299e8907e81ad9a39c016
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|356C / Donor, Lineage, Cell class and subclass (all cells)	MYO1F DISP3 FBXO32 CARNS1	5.70e-05	143	65	4	e8fc6540a48086f58bc3f42dabe392ef46715b9e
ToppCell	PND01-Immune-Immune_Myeloid-DC-cDC2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SH3TC1 MYO1F NCF2 TEP1	7.22e-05	152	65	4	cefc0ab592e99badf145fb95adf9906cb81be81c
ToppCell	PND01-Immune-Immune_Myeloid-DC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SH3TC1 MYO1F NCF2 TEP1	7.22e-05	152	65	4	c8faa83dcaddb2ce2bb890f90dd8e676f7dcb1b3
ToppCell	PND01-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SH3TC1 MYO1F NCF2 TEP1	7.22e-05	152	65	4	c3f00beb8b6fde99263d5ed6bbe3c2415d02f91d
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F RAB11FIP5 NCF2 ABCD1	8.39e-05	158	65	4	ad1040bce6ad655c2502d9abb02507ecff177f83
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F RAB11FIP5 NCF2 ABCD1	8.39e-05	158	65	4	ac7aef01eda1dca80d6c5b508649fcad55803a67
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO1F RNF213 NCF2 TEP1	9.02e-05	161	65	4	5a8698790f9aba796dd2b64af419055c60bd7de8
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Myeloid-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F NCF2 TEP1 NCKAP1L	9.24e-05	162	65	4	4c6e0cadd0ff50b0f50e0cfdc9027210e72674b9
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-CD45____NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS6KA5 MYO1F CBL TBC1D20	9.46e-05	163	65	4	a763c1632d6465a1e753bdc8eadaf819d2b09e5e
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS6KA5 MYO1F CBL TBC1D20	9.46e-05	163	65	4	eaed783eecd07aafa5af844b63c9d816b4da99e4
ToppCell	droplet-Heart-nan-3m-Hematologic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 MYO1F NCF2 NCKAP1L	9.69e-05	164	65	4	df9fe446c1a43100048e11c01bf009bec3414dcf
ToppCell	lung-Club_Cells\|lung / shred on tissue and cell subclass	FMO3 DST RPS6KA5 PLCB4	9.69e-05	164	65	4	b12cacd499b18b96120ca6d14646aebeaed41d10
ToppCell	facs-MAT-Fat-3m-Myeloid-macrophage\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 NCF2 TEP1 NCKAP1L	9.69e-05	164	65	4	b81498c3934e0d52bf0329dc745e02966f9d8613
ToppCell	facs-SCAT-Fat-3m-Myeloid-myeloid_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F NCF2 TEP1 NCKAP1L	1.02e-04	166	65	4	8395c74db8e4e54af97a3f2b75cb75171140ec31
ToppCell	facs-SCAT-Fat-3m-Myeloid\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F NCF2 TEP1 NCKAP1L	1.02e-04	166	65	4	76807edc5620514b53a14be354b84c54c112b8f9
ToppCell	facs-SCAT-Fat-3m-Myeloid-nan\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F NCF2 TEP1 NCKAP1L	1.02e-04	166	65	4	645b842b94b8d2f4b26c2623f8589f56bd782c26
ToppCell	droplet-Heart-nan-3m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 MYO1F NCF2 NCKAP1L	1.04e-04	167	65	4	47447bcf184b1ad24ef17e135199fe7cd1d73c02
ToppCell	droplet-Heart-nan-3m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 MYO1F NCF2 NCKAP1L	1.06e-04	168	65	4	a4eebc78babb9b5ef33065b0642793820195a613
ToppCell	COVID-19_Severe-CD4+_CTL\|World / disease group, cell group and cell class	SYNE1 RAB11FIP5 CARNS1 CBLB	1.09e-04	169	65	4	8c8168ac93a808d7b4756e4491db2b2979df1c1f
ToppCell	facs-GAT-Fat-18m-Myeloid-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 MYO1F NCF2 NCKAP1L	1.09e-04	169	65	4	7a7416fcbffcf57d19b477d9da091e04e3499524
ToppCell	facs-GAT-Fat-18m-Myeloid\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 MYO1F NCF2 NCKAP1L	1.09e-04	169	65	4	0e1a99cd77edcf32bcb513abd247b2b27409ac63
ToppCell	facs-GAT-Fat-18m-Myeloid-myeloid_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 MYO1F NCF2 NCKAP1L	1.09e-04	169	65	4	9bbad31ef03078f5aa456f2e1b17b49c91545ff0
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO1F NCF2 TEP1 NCKAP1L	1.11e-04	170	65	4	6686d1797988216c0d9417f21a2537369abce410
ToppCell	facs-Trachea-nan-18m-Myeloid-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 MYO1F NCF2 NCKAP1L	1.11e-04	170	65	4	774b0c1b453e19651f9481dc6bcabac538c5acb7
ToppCell	facs-GAT-Fat-3m-Myeloid-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 MYO1F NCF2 NCKAP1L	1.14e-04	171	65	4	3f796d53d3110e5d6e97de53bb49d323944659d6
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SYNE1 RNF213 FUS CBLB	1.14e-04	171	65	4	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	facs-GAT-Fat-3m-Myeloid-myeloid_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 MYO1F NCF2 NCKAP1L	1.14e-04	171	65	4	d9fbc2b00dbf9dddc95d9a20d804459a9ebd1820
ToppCell	facs-GAT-Fat-3m-Myeloid\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 MYO1F NCF2 NCKAP1L	1.14e-04	171	65	4	e77bfc925d73ccffe3c8cfb13764e70579a7f942
ToppCell	facs-Trachea-nan-18m-Myeloid\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 MYO1F NCF2 NCKAP1L	1.14e-04	171	65	4	9d496a6edac9663791cda684188d49895246f6fe
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1F NCF2 FAM111B NCKAP1L	1.16e-04	172	65	4	ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F NCF2 TEP1 NCKAP1L	1.22e-04	174	65	4	3533a47885af453d97739e5576e989d93d31be32
ToppCell	facs-Heart-LA-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 MYO1F NCF2 NCKAP1L	1.22e-04	174	65	4	30c083fe4711735e83dccfd00fcd746ae673d353
ToppCell	facs-Heart-LA-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 MYO1F NCF2 NCKAP1L	1.22e-04	174	65	4	46d19c1144fff19be682b7ba59d4c3e014f79e15
ToppCell	facs-Heart-LA-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 MYO1F NCF2 NCKAP1L	1.22e-04	174	65	4	1802a52552256d1e25d8b328ba62dcfe41671900
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F NCF2 TEP1 NCKAP1L	1.22e-04	174	65	4	b487c5c46f074a69b9526a2c72daf218f66aa44b
ToppCell	droplet-Heart-HEART-1m-Hematologic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F NCF2 TEP1 NCKAP1L	1.24e-04	175	65	4	43b9cfd7c47d57244565c641e57f3256b5900804
ToppCell	droplet-Heart-HEART-1m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F NCF2 TEP1 NCKAP1L	1.24e-04	175	65	4	a2fed97cf8d28f9936fe791e5e8c43d2430330c9
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 MYO1F RNF213 FBXO32	1.27e-04	176	65	4	5914e7635474e7cf24d446bdb1423bc0807ee9c6
ToppCell	droplet-Heart-HEART-1m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F NCF2 TEP1 NCKAP1L	1.27e-04	176	65	4	1df640f88667e2dad30e65279d6d33bba75024c1
ToppCell	COVID-19_Severe-CD4+_CTL\|COVID-19_Severe / disease group, cell group and cell class	SYNE1 RAB11FIP5 CARNS1 CBLB	1.30e-04	177	65	4	34e9455790bae905dd91923792f4109d18b7686e
ToppCell	3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KCNH1 MFSD6L PLCB4 FBXO32	1.30e-04	177	65	4	6d89042bda8e244babb68929e84b25edcb545a77
ToppCell	3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KCNH1 MFSD6L PLCB4 FBXO32	1.30e-04	177	65	4	daaccf1249dcf816df4caca695a944f53078291a
ToppCell	3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KCNH1 MFSD6L PLCB4 FBXO32	1.30e-04	177	65	4	338bdda26796bf4e16072878c070212d1006cf57
ToppCell	3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KCNH1 MFSD6L PLCB4 FBXO32	1.30e-04	177	65	4	c5a16f984c836dbf7d0faf061677844167ab612a
ToppCell	Control-Lymphocyte-T_NK-CD4_CTL\|Control / Disease, Lineage and Cell Type	SYNE1 MYO1F RAB11FIP5 FBXO32	1.33e-04	178	65	4	32fbb7a8d7daa7cb37f42923514acbb9090e6811
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-cDC2\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MCTP1 MYO1F NCF2 RGS12	1.33e-04	178	65	4	32120936a524c38e621bd2fca17524fef74422e0
ToppCell	FLU-Healthy-0\|FLU / Virus stimulation, Condition and Cluster	DFFA MYO1F RNF213 FBXO32	1.48e-04	183	65	4	058604ddb06b3bef131183d86b83b422dae8f6cb
ToppCell	normal-na-Lymphocytic_T-CytoT_GZMK+-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 RNF213 CBLB FMO6P	1.48e-04	183	65	4	79defd22b3194dad16db55b9bdd220c09c1e6b90
ToppCell	FLU-Healthy-0\|Healthy / Virus stimulation, Condition and Cluster	DFFA MYO1F RNF213 FBXO32	1.48e-04	183	65	4	7a6f18246c39864479e114f698581f667fa9c600
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KCNH1 HHAT MFSD6L PLCB4	1.51e-04	184	65	4	a60802e11dcc5f932811260b08a95a32f60f6b19
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KCNH1 HHAT MFSD6L PLCB4	1.51e-04	184	65	4	39c230d32e4259bc784e0edfd9e2884c96898564
ToppCell	wk_08-11-Hematologic-Myeloid-DC3\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MCTP1 MYO1F NCF2 NCKAP1L	1.51e-04	184	65	4	7d9294e5a55964903feda135e5bea0338824ed83
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KCNH1 HHAT MFSD6L PLCB4	1.51e-04	184	65	4	2a2fb691cc9414ef5b06c26239d2da03d6d7e5c2
ToppCell	wk_08-11-Hematologic-Myeloid-APOE+_Mac2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MCTP1 MYO1F TMIGD3 NCKAP1L	1.54e-04	185	65	4	8f843badc0e26cb7300c83db56c7974beb90fcf3
ToppCell	normal-na-Lymphocytic_T-CytoT_GZMH+-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 MYO1F RNF213 CBLB	1.54e-04	185	65	4	097d628f92e13250c15b550f2fd1f4225fc07558
ToppCell	normal-na-Lymphocytic_NK-NK_dim-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 MYO1F RNF213 CBLB	1.54e-04	185	65	4	b1a8a8c4d0fc7605eabc17dcb6bd9e8ab4fd578c
ToppCell	Control-Endothelial-Endothelial-Artery\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MCTP1 RPS6KA5 PIK3C2B PLCB4	1.57e-04	186	65	4	2d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RPS6KA5 KCNH1 HHAT PLCB4	1.57e-04	186	65	4	4d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCell	LPS-antiTNF-Myeloid\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO1F NCF2 TBC1D24 NCKAP1L	1.57e-04	186	65	4	839c6da5244f469461b2e5563e36162b2911cd01
ToppCell	facs-Kidney-nan-3m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST SLC25A5 ALDH1L1 KIAA1191	1.60e-04	187	65	4	208686e6ebc9f3a774bcbe89274457ac9449f90e
ToppCell	droplet-Kidney-nan-3m-Epithelial-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST SLC25A5 ALDH1L1 KIAA1191	1.64e-04	188	65	4	6b185d0aaeea64f9ae584a9bcb9741658bb1c7bd
ToppCell	Control-Myeloid-Monocytes\|Control / group, cell type (main and fine annotations)	MCTP1 SH3TC1 MYO1F NCF2	1.67e-04	189	65	4	3335d16bd0ffa0c1ddd06d7da645299148130c3f
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SH3TC1 MYO1F TMIGD3 NCKAP1L	1.67e-04	189	65	4	389ccb68acb82893709f256315111470cf4beed3
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SH3TC1 MYO1F TMIGD3 NCKAP1L	1.67e-04	189	65	4	58465b9407fbce91cca8f199950d6e0054c38fbc
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MCTP1 PIK3C2B DISP3 PLCB4	1.67e-04	189	65	4	c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 RNF213 FUS DDX3X	1.67e-04	189	65	4	0e8d1be3c406d1a393e18faccfe89116a8f82bcf
Computational	Genes upregulated in subsets of cells of a given type within various tumors	DST SYNE1 RNF213 DYNC1H1	5.85e-05	50	46	4	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
Drug	Folic acid [59-30-3]; Up 200; 9uM; HL60; HG-U133A	DFFA ABCD1 ALDH1L1 GMEB2 RGS12 DDX3X PRDM2	1.43e-06	199	64	7	1790_UP
Drug	N,N-dimethylaniline-N-oxide	FMO3 FMO4 FMO6P	3.44e-06	11	64	3	CID000000950
Drug	trimethylamine	FMO3 FMO4 OXCT2 FMO6P	1.74e-05	55	64	4	CID000001146
Drug	betaine	DST OXCT2 ALDH1L1 CBLB SLC3A1 TGS1	2.09e-05	200	64	6	CID000000247
Drug	Clodronate	SLC25A5 SLC25A6	2.33e-05	3	64	2	DB00720
Drug	phenylsuccinate	SLC25A5 SLC25A6 OXCT2	2.72e-05	21	64	3	CID000095459
Disease	amyotrophic lateral sclerosis type 6 (implicated_via_orthology)	EWSR1 TAF15 FUS	8.83e-09	3	62	3	DOID:0060198 (implicated_via_orthology)
Disease	frontotemporal dementia (implicated_via_orthology)	EWSR1 TAF15 FUS	1.92e-06	12	62	3	DOID:9255 (implicated_via_orthology)
Disease	S-methylcysteine measurement	FMO3 FMO6P	4.34e-06	2	62	2	EFO_0800054
Disease	autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2 (implicated_via_orthology)	SLC25A5 SLC25A6	2.60e-05	4	62	2	DOID:0111517 (implicated_via_orthology)
Disease	amyotrophic lateral sclerosis (implicated_via_orthology)	EWSR1 TAF15 FUS	3.44e-05	30	62	3	DOID:332 (implicated_via_orthology)
Disease	Extraskeletal Myxoid Chondrosarcoma	EWSR1 TAF15	4.33e-05	5	62	2	C1275278
Disease	Amyotrophic Lateral Sclerosis	EWSR1 TAF15 FUS	2.51e-04	58	62	3	C0002736
Disease	lentiform nucleus measurement	FMO3 FMO6P	3.89e-04	14	62	2	EFO_0004913
Disease	epilepsy (implicated_via_orthology)	SLC25A5 SLC25A6 KCNH1 DYNC1H1	3.90e-04	163	62	4	DOID:1826 (implicated_via_orthology)
Disease	bipolar disorder (is_implicated_in)	SYNE1 BRD1	1.70e-03	29	62	2	DOID:3312 (is_implicated_in)
Disease	hypertrophic cardiomyopathy (implicated_via_orthology)	SLC25A5 SLC25A6	1.70e-03	29	62	2	DOID:11984 (implicated_via_orthology)
Disease	Severe Congenital Microcephaly	TSEN34 DYNC1H1	1.94e-03	31	62	2	C3853041

Protein segments in the cluster

Peptide	Gene	Start	Entry
AVEWFDGKDFQGSKL	EWSR1	426	Q01844
NKGGAFKKTDDDRWG	BRD1	276	O95696
DCWRKIFRDEGGKAF	SLC25A6	256	P12236
IFRDEGGKAFFKGAW	SLC25A6	261	P12236
TTLACDAKRGWKFDF	DISP3	906	Q9P2K9
IARDEGGKAFFKGAW	SLC25A5	261	P05141
AGGVSKKFVWEAARD	CARNS1	401	A5YM72
FDVDETDSGAGLKWK	DFFA	111	O00273
SGKFSGEELDKLWRE	LRPAP1	161	P30533
LFFTDESGDSRGWKL	C1R	286	P00736
DDTFTFWRGLKDAGL	GMEB2	231	Q9UKD1
VGSDGRFSFWDKDAR	RAE1	291	P78406
AKAAIDWFDGKEFHG	TAF15	296	Q92804
GEEKAKSSWFGLREA	RAB11FIP5	501	Q9BXF6
DLEGTWDTRDKDGFK	NOBOX	11	O60393
EGGWKFEKLDSAARL	ABCD1	676	P33897
REATKGFYDKDSSGW	DDX3X	46	O00571
FEKSNDIGGLWKFSD	FMO3	31	P31513
TAWDKDAGKRDDFIG	MCTP1	536	Q6DN14
AADKKDWKGALDAFS	NCF2	16	P19878
GRTELKGKGAEDTFW	GUCY2D	1041	Q02846
LKFDDSGSWRGRKEE	DST	2546	Q03001
SAKAAIDWFDGKEFS	FUS	346	P35637
ADAAEFWRKFFGDKT	CBLB	176	Q13191
SGTKGKAWAFDLSLE	MFSD6L	226	Q8IWD5
FERSDDIGGLWKFTE	FMO4	31	P31512
NGEKFEFSGLRLDWF	NCKAP1L	476	P55160
EDDSCKGWGKFARLT	KCNH1	141	O95259
FERSDDVGGLWKFSD	FMO6P	31	O60774
IKKGDFSFEGEAWKN	RPS6KA5	641	O75582
GSGDKDRNLSDKWSL	KIAA1191	211	Q96A73
WKEGRGPLDFSKDTS	PIK3C2B	256	O00750
TLFGGLKKDATDFEW	HHAT	46	Q5VTY9
AKKFQERFGSDGAWV	PGBD5	146	Q8N414
AKRSWFGNFISLDKE	BRSK1	591	Q8TDC3
WSKKYEFGESDLRSA	DYNC1H1	4201	Q14204
EKLREFFKWAGDLGA	FAM47A	606	Q5JRC9
ITKADAAEFWRKAFG	CBL	181	P22681
FRSDIGEFEWKLKEG	FAM111B	231	Q6SJ93
GWKRFLDEKSGSFVS	FBXO32	21	Q969P5
RDFGKPSDGKAAWTD	PRDM2	751	Q13029
ESWFGAGKEAKFRSK	GPRASP1	306	Q5JY77
FEEWQAELKGKRGSD	RETSAT	471	Q6NUM9
AKKTDFSWEEERNFG	MRPS27	191	Q92552
VDEFGFFLTWRSEGK	PLCB4	41	Q15147
WFLGAKAAAKESSDR	SYNE1	2421	Q8NF91
ADFKRTSWEAKAEGS	TMEM191A	51	Q9H0A3
SRSADRKDGYVWSGK	SOCS4	21	Q8WXH5
RFWLTKGVDGFSLDA	SLC3A1	301	Q07837
AGDIFFDGAWEREKA	SH3TC1	1116	Q8TE82
AKGDFFWDDGETKDT	SI	826	P14410
DFALVKGWKADRAGN	OXCT2	206	Q9BYC2
LDTSDWEEKEFGFRG	ACD	76	Q96AP0
AAAKDAFENGRWGKI	ALDH1L1	466	O75891
DWSERNKFGGKLGFF	TBC1D24	411	Q9ULP9
FIRGGEEFGESKWDS	RNF213	401	Q63HN8
KGGFWKIHTDERGFS	ZNF287	281	Q9HBT7
RWFAEKFLKGDSSGD	TRIAP1	21	O43715
DEDSEKKRKGAFFSW	RGS12	886	O14924
EATLGRWFDSEEKKG	TEP1	186	Q99973
ARKFDGKDFRWISSG	MTREX	501	P42285
DLWERGFFLSAAGKF	TSEN34	226	Q9BSV6
WDGGAEKADFNAKRK	TBC1D20	16	Q96BZ9
SRFDDGIKLDREGWF	TGS1	656	Q96RS0
KGTLANDFWSGKDLS	TMIGD3	176	P0DMS9
FSDTLQFRVKKEGWG	MYO1F	871	O00160