Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	clathrin-coated pit	AAK1 HIP1R MYO6	5.56e-04	80	42	3	GO:0005905
GeneOntologyCellularComponent	coated vesicle	AAK1 HIP1R GOLGA8K GNAS MYO6	7.43e-04	360	42	5	GO:0030135
GeneOntologyCellularComponent	ruffle	HIP1R GNAS MYO6 ABCA7	7.65e-04	206	42	4	GO:0001726
Domain	SET	PRDM13 PRDM6	4.36e-03	46	40	2	SM00317
Domain	SET_dom	PRDM13 PRDM6	5.13e-03	50	40	2	IPR001214
Domain	SET	PRDM13 PRDM6	5.13e-03	50	40	2	PS50280
Domain	IQ	IQSEC3 MYO6	1.01e-02	71	40	2	PF00612
Pubmed	Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension.	HIP1R MYO6	2.13e-05	6	42	2	31672988
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HIP1R CCDC88C TNRC18 KANSL1 CELSR3 ZNF865 ABCA7 INTS1	4.57e-05	1105	42	8	35748872
Pubmed	Arx acts as a regional key selector gene in the ventral telencephalon mainly through its transcriptional repression activity.	MAGEL2 ZIC5	1.69e-04	16	42	2	19627984
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CCDC88C ZBTB34 TNRC18 MYO6 DHX38	3.10e-04	493	42	5	15368895
Pubmed	Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis.	PRDM13 PRDM6	3.24e-04	22	42	2	19050759
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	AAK1 CCDC88C STOX2 GNAS DCP1B ARHGEF17	5.55e-04	861	42	6	36931259
Pubmed	TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer.	GNAS DHX38	6.06e-04	30	42	2	34285210
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	CCDC88C SFSWAP ZNF865 ZIC5 INTS1	6.63e-04	583	42	5	29844126
Pubmed	Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes.	KLHL29 IRX3	6.90e-04	32	42	2	21546767
Pubmed	Functional analysis and identification of cis-regulatory elements of human chromosome 21 gene promoters.	PAXBP1 MX1	7.79e-04	34	42	2	20494980
Pubmed	Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization.	GOLGA8K MYO6	7.79e-04	34	42	2	23533177
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	IRX3 PAXBP1 GNAS SFSWAP DCP1B ZIC5	7.93e-04	922	42	6	27609421
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	CACTIN PAXBP1 KANSL1 SFSWAP ZIC5 DHX38 INTS1	8.37e-04	1294	42	7	30804502
Pubmed	PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression.	ZBTB34 PRDM6	1.13e-03	41	42	2	21282332
Pubmed	A GO catalogue of human DNA-binding transcription factors.	STOX2 SKIDA1	1.19e-03	42	42	2	34673265
Cytoband	12p13.33	IQSEC3 DCP1B	1.38e-04	19	42	2	12p13.33
Cytoband	15q13.3	GOLGA8K FMN1	2.62e-04	26	42	2	15q13.3
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM13 PRDM6	1.90e-04	17	22	2	1197
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZBTB34 ZNF865 ZIC5 PRDM6	1.02e-02	718	22	4	28
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KLHL29 ZBTB34	1.14e-02	134	22	2	861
Coexpression	PEREZ_TP53_TARGETS	HIP1R ZBTB34 STOX2 PAXBP1 GNAS ARHGEF17 MYO6 ABCA7 PRDM6 MX1	1.51e-05	1201	42	10	M4391
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRDM13 IQSEC3 BCAS1 ZIC5 SKIDA1	8.60e-07	186	42	5	bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell	droplet-Fat-Bat-18m\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STOX2 SFSWAP PRDM6 INTS1	1.97e-05	170	42	4	c720d81bc29a8fd1f1249c6af408471d561f1d5d
ToppCell	droplet-Fat-Bat\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STOX2 SFSWAP PRDM6 INTS1	1.97e-05	170	42	4	c4ecdfc2b4710da0a5fbb20e9df02536023badb1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL29 STOX2 IRX3 BCAS1	2.26e-05	176	42	4	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL29 STOX2 IRX3 AJAP1	2.52e-05	181	42	4	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	AT1-AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	TNNI3K FNDC1 THNSL2 ABCA7	2.63e-05	183	42	4	6821dca076318115d360ff426eb1218cfe104063
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL29 STOX2 IRX3 BCAS1	2.68e-05	184	42	4	da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	HIP1R IRX3 CPNE4 FMN1	2.86e-05	187	42	4	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	AAK1 CCDC88C GNAS KANSL1	2.98e-05	189	42	4	0e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL29 STOX2 IRX3 BCAS1	2.98e-05	189	42	4	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ZBTB34 MAGEL2 GNAS ARHGEF17	3.04e-05	190	42	4	84fbd5664ec886120963d4f50dfa1fd1851d36c1
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	AAK1 CCDC88C MYO6 MX1	3.72e-05	200	42	4	109f673a4967ffa52270a0b4f818b3461288db44
Disease	Muscle hypotonia	KANSL1 INTS1	2.29e-04	17	39	2	C0026827
Disease	blood vanadium measurement	GNAS AJAP1	7.23e-04	30	39	2	EFO_0021533
Disease	hyperuricemia	BCAS1 GNAS	8.76e-04	33	39	2	EFO_0009104
Disease	guilt measurement	KLHL29 KANSL1	1.29e-03	40	39	2	EFO_0009595

Protein segments in the cluster

Peptide	Gene	Start	Entry
EFAPTAISAPVHKAA	AAK1	881	Q2M2I8
AHRPRDQAAALVPKA	AJAP1	101	Q9UKB5
HRFSAPEVPAEVAKV	ABCA7	1316	Q8IZY2
IRPAAHAEFVPKADL	FMN1	356	Q68DA7
HRKFLAAAHNPADEP	GOLGA8S	536	H3BPF8
PATAHRNFHLDPKLA	ARHGEF17	896	Q96PE2
HREAAAVPAAKMPAF	OTUD1	61	Q5VV17
FCAPKAVSAARAHLP	MAGEL2	756	Q9UJ55
APAAISFLQKHADPL	INTS1	1971	Q8N201
FDAPKFRLHSATLAP	NUDT22	56	Q9BRQ3
LLHFSPAAAPAARTK	CCDC88C	1926	Q9P219
AAAEAHHIRFKLAPP	KANSL1	11	Q7Z3B3
PGEIPDAAFIHAARK	PAXBP1	216	Q9Y5B6
AAAVAAGRPSAHAPK	IQSEC3	226	Q9UPP2
LPVFAPLAAAAVAAE	PRDM6	116	Q9NQX0
HASNRPALAAKFPVL	DCP1B	466	Q8IZD4
PPNFLRASALAEHIK	HIP1R	286	O75146
HRKFLAAAHNPADEP	GOLGA8K	541	D6RF30
VRAPAHAARAKEAAA	FNDC1	1091	Q4ZHG4
VPFRNFKHASPAALA	CPNE4	506	Q96A23
DNKDFAILRFHAGPP	CACTIN	701	Q8WUQ7
PAARAAAAAAFEIDP	CELSR3	476	Q9NYQ7
HAPAQDKVLSAARDP	BCAS1	156	O75363
AFKHVERAPPAAAAL	PRDM13	401	Q9H4Q3
AAAAHRLVSAPLGKF	IRX3	391	P78415
AAATSKFPPHRFIAD	MRPL57	76	Q9BQC6
DPDHPLAALVRKAQA	SFSWAP	321	Q12872
APAAAETRAAHVAPA	GNAS	476	Q5JWF2
RFKRAELPAHAAAAP	FOXE3	166	Q13461
AAARPAAHLPQIFSK	SKIDA1	161	Q1XH10
LAPASAAKFPEAVLA	THNSL2	416	Q86YJ6
RIFLHDASAAAPAPV	TNRC18	2001	O15417
LLRHKAAHAPPAAAA	ZNF865	456	P0CJ78
AAHAPPAAAAEAPKD	ZNF865	461	P0CJ78
LADFVKIAHPEPAFR	MIPEP	121	Q99797
LHKRFPAAFAPQASR	STOX2	36	Q9P2F5
SAASEQHVFKAPAPR	DHX38	31	Q92620
GEIPFAHLKPAAAAA	TNNI3K	661	Q59H18
QPFRAHKAVLAASSP	ZBTB34	41	Q8NCN2
FPAHPEAPAAAARAA	ZIC5	111	Q96T25
EAVAPLPKAVHSAAA	KLHL29	711	Q96CT2
VDIAKADPAAASHPL	MX1	6	P20591
GTRPPHVFAIADKAF	MYO6	121	Q9UM54