Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	peptide lactyltransferase (CoA-dependent) activity	CREBBP EP300	4.88e-05	2	140	2	GO:0120300
GeneOntologyMolecularFunction	histone H3K27 acetyltransferase activity	CREBBP EP300	4.88e-05	2	140	2	GO:0044017
GeneOntologyMolecularFunction	histone H3K18 acetyltransferase activity	CREBBP EP300	1.46e-04	3	140	2	GO:0043993
GeneOntologyMolecularFunction	transcription coregulator activity	SUPT20HL1 SIAH2 DAXX BCL9 SSBP3 CREBBP PPARGC1A KMT2C ATF7IP ZMIZ2 IRF2BPL MAML3 EP300	1.67e-04	562	140	13	GO:0003712
GeneOntologyMolecularFunction	transcription coactivator activity	DAXX BCL9 SSBP3 CREBBP PPARGC1A KMT2C ZMIZ2 MAML3 EP300	2.92e-04	303	140	9	GO:0003713
GeneOntologyMolecularFunction	peroxisome proliferator activated receptor binding	CREBBP PPARGC1A EP300	4.09e-04	21	140	3	GO:0042975
GeneOntologyMolecularFunction	SH3 domain binding	REPS1 WIPF1 TOM1L1 MAPK15 RIMS1 INPP5J	5.19e-04	143	140	6	GO:0017124
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	IQSEC3 RASGRF2 STXBP5 MCF2L2 OCRL PLEKHG5 PLEKHG4B TBC1D1 RIN2 RIMS1 PLXNB1	9.06e-04	507	140	11	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	IQSEC3 RASGRF2 STXBP5 MCF2L2 OCRL PLEKHG5 PLEKHG4B TBC1D1 RIN2 RIMS1 PLXNB1	9.06e-04	507	140	11	GO:0030695
GeneOntologyMolecularFunction	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	OCRL INPP5J	1.00e-03	7	140	2	GO:0052659
GeneOntologyMolecularFunction	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	OCRL INPP5J	1.00e-03	7	140	2	GO:0034485
GeneOntologyMolecularFunction	molecular adaptor activity	SUPT20HL1 RBM33 CAPN3 SIAH2 DAXX BCL9 SSBP3 CREBBP AR PPARGC1A FRMD4A KMT2C GAS2L2 ATF7IP ZMIZ2 SYN1 IRF2BPL BAG6 MAML3 EP300	1.25e-03	1356	140	20	GO:0060090
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	SUPT20HL1 RBM33 SIAH2 DAXX BCL9 SSBP3 CREBBP AR PPARGC1A FRMD4A KMT2C GAS2L2 ATF7IP ZMIZ2 SYN1 IRF2BPL MAML3 EP300	1.27e-03	1160	140	18	GO:0030674
GeneOntologyMolecularFunction	inositol-polyphosphate 5-phosphatase activity	OCRL INPP5J	1.33e-03	8	140	2	GO:0004445
GeneOntologyMolecularFunction	inositol-1,4,5-trisphosphate 5-phosphatase activity	OCRL INPP5J	1.33e-03	8	140	2	GO:0052658
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	SETD1B KMT2C	1.33e-03	8	140	2	GO:0140945
GeneOntologyMolecularFunction	beta-catenin binding	AMER1 BCL9 AR EP300 CDH15	1.58e-03	120	140	5	GO:0008013
GeneOntologyMolecularFunction	nuclear androgen receptor binding	DAXX AR EP300	1.58e-03	33	140	3	GO:0050681
GeneOntologyMolecularFunction	inositol tetrakisphosphate phosphatase activity	OCRL INPP5J	1.70e-03	9	140	2	GO:0052743
GeneOntologyMolecularFunction	chromatin binding	EP400 MBD6 CREBBP AR PHC1 PPARGC1A MAPK15 NFATC3 ATXN7 AUTS2 DMRT1 EP300 CRAMP1	2.11e-03	739	140	13	GO:0003682
GeneOntologyMolecularFunction	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	OCRL INPP5J	2.12e-03	10	140	2	GO:0004439
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	SETD1B KMT2C	2.12e-03	10	140	2	GO:0140999
GeneOntologyMolecularFunction	enzyme regulator activity	IQSEC3 RASGRF2 APOA5 STXBP5 TOM1L1 CAPN3 MCF2L2 DAXX PPP6R1 OCRL PDPK2P PLEKHG5 PLEKHG4B SERPINA11 TBC1D1 RIN2 PRKAR2A PPP1R9B RIMS1 PLXNB1	2.12e-03	1418	140	20	GO:0030234
GeneOntologyMolecularFunction	phosphatidylinositol trisphosphate phosphatase activity	OCRL INPP5J	2.58e-03	11	140	2	GO:0034594
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	HJV ONECUT2 SUPT20HL1 ZNF142 HIVEP1 ZNF629 ETV5 DAXX RREB1 BCL9 SSBP3 CREBBP AR TFE3 PPARGC1A KMT2C NFATC3 ATXN7 ZMIZ2 AUTS2 IRF2BPL DMRT1 FUBP3 MAML3 EP300	3.92e-06	1390	136	25	GO:0045944
HumanPheno	Corneal scarring	OCRL CREBBP ZNF469 ZFHX2 EP300	1.34e-06	21	50	5	HP:0000559
HumanPheno	Natal tooth	AMER1 CREBBP KMT2C KDF1 EP300	2.92e-05	38	50	5	HP:0000695
HumanPheno	Advanced eruption of teeth	AMER1 CREBBP KMT2C KDF1 EP300	7.52e-05	46	50	5	HP:0006288
HumanPheno	Plantar crease between first and second toes	CREBBP EP300	9.44e-05	2	50	2	HP:0008107
HumanPheno	Aortic isthmus hypoplasia	CREBBP EP300	9.44e-05	2	50	2	HP:0034227
HumanPheno	High axial triradius	CREBBP EP300	9.44e-05	2	50	2	HP:0001042
HumanPheno	Supernumerary tooth	HSPG2 AMER1 CREBBP KMT2C KDF1 EP300	1.60e-04	85	50	6	HP:0011069
HumanPheno	Bilateral cryptorchidism	AMH CREBBP AR KIAA0753 EP300	1.64e-04	54	50	5	HP:0008689
HumanPheno	Keloids	OCRL CREBBP EP300	2.38e-04	13	50	3	HP:0010562
HumanPheno	Laryngeal cartilage malformation	CREBBP EP300	2.82e-04	3	50	2	HP:0008752
HumanPheno	Phobia	CREBBP EP300	2.82e-04	3	50	2	HP:5200232
HumanPheno	Agoraphobia	CREBBP EP300	2.82e-04	3	50	2	HP:0000756
HumanPheno	Humoral immunodeficiency	CREBBP EP300	2.82e-04	3	50	2	HP:0005363
HumanPheno	Prominent nasal septum	CREBBP EP300	2.82e-04	3	50	2	HP:0005322
HumanPheno	Radial deviation of thumb terminal phalanx	CREBBP EP300	2.82e-04	3	50	2	HP:0005895
HumanPheno	Duplication of phalanx of hallux	CREBBP KIAA0753 EP300	3.00e-04	14	50	3	HP:0010066
Domain	Nuc_rcpt_coact_CREBbp	CREBBP EP300	5.26e-05	2	136	2	IPR014744
Domain	ZnF_TAZ	CREBBP EP300	5.26e-05	2	136	2	SM00551
Domain	-	CREBBP EP300	5.26e-05	2	136	2	1.20.1020.10
Domain	RING_CBP-p300	CREBBP EP300	5.26e-05	2	136	2	IPR010303
Domain	-	CREBBP EP300	5.26e-05	2	136	2	1.10.1630.10
Domain	Creb_binding	CREBBP EP300	5.26e-05	2	136	2	PF09030
Domain	zf-TAZ	CREBBP EP300	5.26e-05	2	136	2	PF02135
Domain	ZF_TAZ	CREBBP EP300	5.26e-05	2	136	2	PS50134
Domain	KAT11	CREBBP EP300	5.26e-05	2	136	2	SM01250
Domain	Znf_TAZ	CREBBP EP300	5.26e-05	2	136	2	IPR000197
Domain	KIX	CREBBP EP300	5.26e-05	2	136	2	PF02172
Domain	HAT_KAT11	CREBBP EP300	5.26e-05	2	136	2	PF08214
Domain	KIX	CREBBP EP300	5.26e-05	2	136	2	PS50952
Domain	CBP_P300_HAT	CREBBP EP300	5.26e-05	2	136	2	IPR031162
Domain	DUF902	CREBBP EP300	5.26e-05	2	136	2	PF06001
Domain	-	CREBBP EP300	5.26e-05	2	136	2	1.10.246.20
Domain	Histone_AcTrfase_Rtt109/CBP	CREBBP EP300	5.26e-05	2	136	2	IPR013178
Domain	KIX_dom	CREBBP EP300	5.26e-05	2	136	2	IPR003101
Domain	CBP_P300_HAT	CREBBP EP300	5.26e-05	2	136	2	PS51727
Domain	PH_dom-like	IQSEC3 RASGRF2 FRMPD1 MCF2L2 PLEKHA4 PLEKHG5 PLEKHG4B FRMD4A TBC1D1 PHLPP1 TNS4 TECPR1	6.73e-05	426	136	12	IPR011993
Domain	HMGI/Y_DNA-bd_CS	CECR2 PLEKHA4 KMT2C PRB4	7.27e-05	31	136	4	IPR000637
Domain	SEA	HSPG2 MUC3B MUC3A	1.30e-04	14	136	3	SM00200
Domain	-	IQSEC3 RASGRF2 MCF2L2 PLEKHA4 PLEKHG5 PLEKHG4B FRMD4A TBC1D1 PHLPP1 TNS4 TECPR1	1.38e-04	391	136	11	2.30.29.30
Domain	ZF_ZZ_2	DRP2 CREBBP EP300	2.84e-04	18	136	3	PS50135
Domain	ZF_ZZ_1	DRP2 CREBBP EP300	2.84e-04	18	136	3	PS01357
Domain	ZZ	DRP2 CREBBP EP300	2.84e-04	18	136	3	PF00569
Domain	Znf_ZZ	DRP2 CREBBP EP300	3.36e-04	19	136	3	IPR000433
Domain	ZnF_ZZ	DRP2 CREBBP EP300	3.36e-04	19	136	3	SM00291
Domain	SEA	HSPG2 MUC3B MUC3A	6.01e-04	23	136	3	PS50024
Domain	SEA_dom	HSPG2 MUC3B MUC3A	6.01e-04	23	136	3	IPR000082
Domain	Nuc_rcpt_coact	CREBBP EP300	7.75e-04	6	136	2	IPR009110
Domain	Znf_CCCH	RC3H1 ZC3H12B ZC3H6 ZC3H7B	8.42e-04	58	136	4	IPR000571
Domain	ZF_C3H1	RC3H1 ZC3H12B ZC3H6 ZC3H7B	8.42e-04	58	136	4	PS50103
Domain	Bromodomain_CS	CECR2 CREBBP EP300	8.69e-04	26	136	3	IPR018359
Domain	PH	IQSEC3 RASGRF2 MCF2L2 PLEKHA4 PLEKHG5 PLEKHG4B PHLPP1 TECPR1	9.93e-04	278	136	8	SM00233
Domain	PH_DOMAIN	IQSEC3 RASGRF2 MCF2L2 PLEKHA4 PLEKHG5 PLEKHG4B PHLPP1 TECPR1	1.02e-03	279	136	8	PS50003
Domain	PH_domain	IQSEC3 RASGRF2 MCF2L2 PLEKHA4 PLEKHG5 PLEKHG4B PHLPP1 TECPR1	1.04e-03	280	136	8	IPR001849
Domain	DH_1	RASGRF2 MCF2L2 PLEKHG5 PLEKHG4B	1.15e-03	63	136	4	PS00741
Domain	RhoGEF	RASGRF2 MCF2L2 PLEKHG5 PLEKHG4B	1.53e-03	68	136	4	SM00325
Domain	RhoGEF	RASGRF2 MCF2L2 PLEKHG5 PLEKHG4B	1.70e-03	70	136	4	PF00621
Domain	DH_2	RASGRF2 MCF2L2 PLEKHG5 PLEKHG4B	1.70e-03	70	136	4	PS50010
Domain	-	RASGRF2 MCF2L2 PLEKHG5 PLEKHG4B	1.79e-03	71	136	4	1.20.900.10
Domain	DH-domain	RASGRF2 MCF2L2 PLEKHG5 PLEKHG4B	1.79e-03	71	136	4	IPR000219
Domain	IPPc	OCRL INPP5J	2.28e-03	10	136	2	IPR000300
Domain	IPPc	OCRL INPP5J	2.28e-03	10	136	2	SM00128
Pathway	BIOCARTA_PPARG_PATHWAY	CREBBP PPARGC1A EP300	9.86e-06	7	94	3	MM1573
Pathway	REACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS	DAXX CREBBP PHC1 PPARGC1A EP300	1.05e-05	44	94	5	M27295
Pathway	BIOCARTA_PPARG_PATHWAY	CREBBP PPARGC1A EP300	1.57e-05	8	94	3	M22058
Pathway	WP_ANDROGEN_RECEPTOR_SIGNALING	ETV5 DAXX ZNF318 CREBBP AR EP300	3.16e-05	91	94	6	M39700
Pathway	BIOCARTA_CARM1_PATHWAY	CREBBP PRKAR2A EP300	4.56e-05	11	94	3	MM1521
Pathway	BIOCARTA_CARM1_PATHWAY	CREBBP PRKAR2A EP300	6.05e-05	12	94	3	M7968
Pathway	REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	CREBBP MAML3 EP300	9.91e-05	14	94	3	M27808
Pathway	PID_FOXM1_PATHWAY	ETV5 CREBBP NFATC3 EP300	1.41e-04	40	94	4	M176
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS	CREBBP MAML3 EP300	1.51e-04	16	94	3	M27121
Pathway	REACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	CREBBP MAML3 EP300	3.01e-04	20	94	3	M27881
Pathway	REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE	PLEKHA4 PI4K2A OCRL INPP5J	3.38e-04	50	94	4	MM14641
Pathway	BIOCARTA_PPARA_PATHWAY	CREBBP PPARGC1A PRKAR2A EP300	3.93e-04	52	94	4	M2404
Pathway	REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE	PLEKHA4 PI4K2A OCRL INPP5J	4.23e-04	53	94	4	M662
Pathway	PID_AR_TF_PATHWAY	CREBBP AR ZMIZ2 EP300	4.23e-04	53	94	4	M151
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP EP300	4.34e-04	5	94	2	MM1575
Pathway	REACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES	CREBBP EP300	4.34e-04	5	94	2	M48020
Pathway	REACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES	CREBBP EP300	4.34e-04	5	94	2	M48023
Pathway	REACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION	CREBBP EP300	4.34e-04	5	94	2	M27228
Pathway	REACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	CREBBP MAML3 EP300	5.94e-04	25	94	3	M27880
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP EP300	6.48e-04	6	94	2	M22062
Pathway	BIOCARTA_CARM_ER_PATHWAY	CREBBP PPARGC1A EP300	6.68e-04	26	94	3	M2499
Pathway	PID_HDAC_CLASSIII_PATHWAY	CREBBP PPARGC1A EP300	6.68e-04	26	94	3	M32
Pathway	WP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA	CREBBP KMT2C MAML3 EP300	9.20e-04	65	94	4	M39682
Pathway	REACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES	CREBBP EP300	1.20e-03	8	94	2	M48022
Pathway	REACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION	CREBBP EP300	1.20e-03	8	94	2	M48024
Pathway	REACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES	CREBBP EP300	1.20e-03	8	94	2	M46443
Pathway	WP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR	CREBBP NFATC3 EP300	1.24e-03	32	94	3	M39521
Pubmed	Human transcription factor protein interaction networks.	HSPG2 HIVEP1 EP400 RBM33 RC3H1 ZNF629 ETV5 ZNF318 PPP6R1 RREB1 BCL9 SSBP3 MBD6 CREBBP TFE3 KMT2C RBM12 NFATC3 ATXN7 ATF7IP ZMIZ2 AUTS2 IRF2BPL CCDC86 FUBP3 PRRC2A EP300	3.09e-11	1429	143	27	35140242
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	SF3B4 RBM33 RC3H1 BCL9 SSBP3 CREBBP RBM12 ZMIZ2 AUTS2 EP300	8.19e-10	152	143	10	38360978
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	POU6F2 AMER1 NEK6 TOM1L1 FRMPD1 TTC14 SSBP3 CREBBP AR TTC19 PLEKHG4B KMT2C ATXN7 TBC1D1 RIN2 AUTS2 ZFHX2 PPP1R9B RIMS1 GREB1 MAML3 EP300 CRAMP1 WNK2 CDH15	2.07e-09	1489	143	25	28611215
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	HIVEP1 EP400 PI4K2A BUD13 DAXX ZNF318 RREB1 BCL9 TUBGCP6 FASN LATS1 ATXN7 IRF2BPL RIMS1 CCDC86 PRRC2A BAG6 WDR62	3.52e-09	774	143	18	15302935
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	HIVEP1 NEK6 WIPF1 EP400 RBM33 ZNF629 ETV5 ZNF318 RREB1 BCL9 ZNF414 CREBBP KMT2C FASN RBM12 ZMIZ2 FUBP3 PRRC2A BAG6 EP300	2.91e-08	1103	143	20	34189442
Pubmed	Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300.	EP400 CREBBP EP300	6.81e-08	3	143	3	9590171
Pubmed	A human MAP kinase interactome.	ZNF142 HIVEP1 WIPF1 RBM33 TOM1L1 DAXX LCP2 CREBBP KMT2C LATS1 ATF7IP EP300 WNK2	1.22e-07	486	143	13	20936779
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HSPG2 FAM193B SETD1B REPS1 EP400 SIAH2 PPP6R1 BCL9 MBD6 PLEKHG5 TFE3 FAM83H KMT2C FASN ZMIZ2 ZC3H7B EP300 CRAMP1 WNK2	1.51e-07	1105	143	19	35748872
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	HSPG2 FAM193B HIVEP1 SIAH2 MBD6 TTC19 ATXN7 DZIP3 ZC3H7B FUBP3 PRRC2A BAG6 WNK2 CCDC33	2.42e-07	608	143	14	16713569
Pubmed	MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.	CREBBP KMT2C EP300	2.71e-07	4	143	3	28398509
Pubmed	Binding and modulation of p53 by p300/CBP coactivators.	EP400 CREBBP EP300	2.71e-07	4	143	3	9194565
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	RBM33 RC3H1 BCL9 GPKOW CREBBP FAM83H KMT2C RBM12 AUTS2 FUBP3 MAML3 EP300	4.62e-07	457	143	12	32344865
Pubmed	JS-K, a nitric oxide pro-drug, regulates growth and apoptosis through the ubiquitin-proteasome pathway in prostate cancer cells.	SIAH2 AR EP300	1.35e-06	6	143	3	28549433
Pubmed	Regulation of T cell activation by HIV-1 accessory proteins: Vpr acts via distinct mechanisms to cooperate with Nef in NFAT-directed gene expression and to promote transactivation by CREB.	CREBBP NFATC3 EP300	1.35e-06	6	143	3	12788643
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	AFF2 SPATA31E1 EP400 BCL9 PLEKHG4B ZNF469 LATS1 ZMIZ2 IRF2BPL WNK2 TECPR1	1.82e-06	430	143	11	35044719
Pubmed	Interaction network of human early embryonic transcription factors.	HIVEP1 EP400 RREB1 BCL9 MBD6 CREBBP KMT2C ZMIZ2 AUTS2 EP300	2.10e-06	351	143	10	38297188
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	EP400 CECR2 PLEKHG5 TUBGCP6 KMT2C RBM12 CASKIN2 AUTS2 ZC3H7B CRAMP1 WNK2 PLXNB1	2.12e-06	529	143	12	14621295
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	SETD1B EP400 MBD6 CREBBP PHC1 AUTS2 EP300	4.18e-06	157	143	7	30186101
Pubmed	Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	IQSEC3 SETD1B PPP6R1 TBC1D1 ZFHX2 ZC3H7B	4.74e-06	104	143	6	10470851
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	HIVEP1 ETV5 KMT2C ATXN7 CRAMP1 WNK2 TECPR1 CCDC33	5.88e-06	233	143	8	37704626
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	HIVEP1 EP400 CECR2 RREB1 CREBBP KMT2C ATF7IP ZMIZ2 AUTS2 EP300	6.37e-06	398	143	10	35016035
Pubmed	Natural helix 9 mutants of PPARγ differently affect its transcriptional activity.	CREBBP PPARGC1A EP300	8.00e-06	10	143	3	30595551
Pubmed	SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells.	EP400 CREBBP AR	8.00e-06	10	143	3	18087039
Pubmed	Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes.	CREBBP PPARGC1A EP300	1.10e-05	11	143	3	15681609
Pubmed	Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator.	CREBBP PPARGC1A EP300	1.46e-05	12	143	3	12189208
Pubmed	Loss of p300 accelerates MDS-associated leukemogenesis.	CREBBP EP300	1.68e-05	2	143	2	27881875
Pubmed	Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.	CREBBP EP300	1.68e-05	2	143	2	34845315
Pubmed	p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.	CREBBP EP300	1.68e-05	2	143	2	19729597
Pubmed	The zinc finger protein ras-responsive element binding protein-1 is a coregulator of the androgen receptor: implications for the role of the Ras pathway in enhancing androgenic signaling in prostate cancer.	RREB1 AR	1.68e-05	2	143	2	17550981
Pubmed	Modifiers of ovarian function in girls and women with classic galactosemia.	AMH GALT	1.68e-05	2	143	2	23690308
Pubmed	CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.	CREBBP EP300	1.68e-05	2	143	2	39287984
Pubmed	Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.	CREBBP EP300	1.68e-05	2	143	2	20717166
Pubmed	The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.	CREBBP EP300	1.68e-05	2	143	2	25893291
Pubmed	Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.	CREBBP EP300	1.68e-05	2	143	2	11559821
Pubmed	Peroxisome proliferator-activated receptor gamma coactivator-1alpha interacts with the androgen receptor (AR) and promotes prostate cancer cell growth by activating the AR.	AR PPARGC1A	1.68e-05	2	143	2	19884383
Pubmed	CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.	CREBBP EP300	1.68e-05	2	143	2	32576962
Pubmed	Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.	CREBBP EP300	1.68e-05	2	143	2	19822209
Pubmed	A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.	CREBBP EP300	1.68e-05	2	143	2	24522976
Pubmed	Direct Interaction of Daxx and Androgen Receptor Is Required for Their Regulatory Activity in Cholesterol Biosynthesis.	DAXX AR	1.68e-05	2	143	2	32694250
Pubmed	Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B.	MUC3B MUC3A	1.68e-05	2	143	2	10973822
Pubmed	CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.	CREBBP EP300	1.68e-05	2	143	2	21847097
Pubmed	Müllerian-inhibiting substance function during mammalian sexual development.	AMH AR	1.68e-05	2	143	2	7954809
Pubmed	p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.	CREBBP EP300	1.68e-05	2	143	2	34813504
Pubmed	Rubinstein-Taybi Syndrome	CREBBP EP300	1.68e-05	2	143	2	20301699
Pubmed	Potential biomarker of metformin action.	CREBBP EP300	1.68e-05	2	143	2	24639469
Pubmed	The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.	CREBBP EP300	1.68e-05	2	143	2	37816914
Pubmed	Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor.	CREBBP AR	1.68e-05	2	143	2	20541699
Pubmed	Transcription Factor Tfe3 Directly Regulates Pgc-1alpha in Muscle.	TFE3 PPARGC1A	1.68e-05	2	143	2	25736533
Pubmed	SUMO modification negatively modulates the transcriptional activity of CREB-binding protein via the recruitment of Daxx.	DAXX CREBBP	1.68e-05	2	143	2	16287980
Pubmed	BAT2 and BAT3 polymorphisms as novel genetic risk factors for rejection after HLA-related SCT.	PRRC2A BAG6	1.68e-05	2	143	2	25111513
Pubmed	Hormonal and cellular regulation of Sertoli cell anti-Müllerian hormone production in the postnatal mouse.	AMH AR	1.68e-05	2	143	2	9294098
Pubmed	Binding of p300/CBP co-activators by polyoma large T antigen.	CREBBP EP300	1.68e-05	2	143	2	11438528
Pubmed	Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.	CREBBP EP300	1.68e-05	2	143	2	10918613
Pubmed	Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.	CREBBP EP300	1.68e-05	2	143	2	35502657
Pubmed	p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.	CREBBP EP300	1.68e-05	2	143	2	31898871
Pubmed	CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1.	CREBBP AR	1.68e-05	2	143	2	9822653
Pubmed	A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain.	PRRC2A BAG6	1.68e-05	2	143	2	2156268
Pubmed	Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.	CREBBP EP300	1.68e-05	2	143	2	30888860
Pubmed	Differential Lipid Response to Statins Is Associated With Variants in the BUD13-APOA5 Gene Region.	APOA5 BUD13	1.68e-05	2	143	2	25900265
Pubmed	Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.	CREBBP EP300	1.68e-05	2	143	2	27881443
Pubmed	Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.	CREBBP EP300	1.68e-05	2	143	2	19272189
Pubmed	Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.	CREBBP EP300	1.68e-05	2	143	2	32690000
Pubmed	CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.	CREBBP EP300	1.68e-05	2	143	2	30953353
Pubmed	Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.	CREBBP EP300	1.68e-05	2	143	2	21803292
Pubmed	HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.	CREBBP EP300	1.68e-05	2	143	2	9811832
Pubmed	Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.	CREBBP EP300	1.68e-05	2	143	2	24089570
Pubmed	Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8(+) T Cell Exhaustion.	PDCD1 PPARGC1A	1.68e-05	2	143	2	27496729
Pubmed	Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.	CREBBP EP300	1.68e-05	2	143	2	15706485
Pubmed	AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.	CREBBP EP300	1.68e-05	2	143	2	39266679
Pubmed	A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.	CREBBP EP300	1.68e-05	2	143	2	22303793
Pubmed	Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.	CREBBP EP300	1.68e-05	2	143	2	34732714
Pubmed	Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.	CREBBP EP300	1.68e-05	2	143	2	34019788
Pubmed	GREB1 amplifies androgen receptor output in human prostate cancer and contributes to antiandrogen resistance.	AR GREB1	1.68e-05	2	143	2	30644358
Pubmed	BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization.	BAG6 EP300	1.68e-05	2	143	2	24852146
Pubmed	Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.	CREBBP EP300	1.68e-05	2	143	2	15860545
Pubmed	Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.	CREBBP EP300	1.68e-05	2	143	2	29460469
Pubmed	Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.	CREBBP EP300	1.68e-05	2	143	2	24551300
Pubmed	Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus.	MUC3B MUC3A	1.68e-05	2	143	2	12958310
Pubmed	Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.	CREBBP EP300	1.68e-05	2	143	2	33911074
Pubmed	The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.	CREBBP EP300	1.68e-05	2	143	2	9018065
Pubmed	Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.	CREBBP EP300	1.68e-05	2	143	2	24648406
Pubmed	CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.	CREBBP EP300	1.68e-05	2	143	2	30135524
Pubmed	Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.	CREBBP EP300	1.68e-05	2	143	2	16596650
Pubmed	The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.	CREBBP EP300	1.68e-05	2	143	2	29217654
Pubmed	Targeting ADT-Induced Activation of the E3 Ubiquitin Ligase Siah2 to Delay the Occurrence of Castration-Resistant Prostate Cancer.	SIAH2 AR	1.68e-05	2	143	2	33937036
Pubmed	Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.	CREBBP EP300	1.68e-05	2	143	2	10049825
Pubmed	CBP/p300 acetyltransferase activity in hematologic malignancies.	CREBBP EP300	1.68e-05	2	143	2	27380996
Pubmed	CREBBP and p300 lysine acetyl transferases in the DNA damage response.	CREBBP EP300	1.68e-05	2	143	2	29170789
Pubmed	Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.	CREBBP EP300	1.68e-05	2	143	2	21555743
Pubmed	CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.	CREBBP EP300	1.68e-05	2	143	2	12646247
Pubmed	P300 acetyltransferase regulates fatty acid synthase expression, lipid metabolism and prostate cancer growth.	FASN EP300	1.68e-05	2	143	2	26934656
Pubmed	Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.	CREBBP EP300	1.68e-05	2	143	2	11867645
Pubmed	Expression of fatty acid synthase is regulated by PGC‑1α and contributes to increased cell proliferation.	PPARGC1A FASN	1.68e-05	2	143	2	29130104
Pubmed	Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.	CREBBP EP300	1.68e-05	2	143	2	11963968
Pubmed	Effects of androgen receptor mutation on testicular histopathology of patient having complete androgen insensitivity.	AMH AR	1.68e-05	2	143	2	28299491
Pubmed	MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region.	MUC3B MUC3A	1.68e-05	2	143	2	9334251
Pubmed	Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.	CREBBP EP300	1.68e-05	2	143	2	9528808
Pubmed	Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.	CREBBP EP300	1.68e-05	2	143	2	12696060
Pubmed	CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.	CREBBP EP300	1.68e-05	2	143	2	36109165
Pubmed	Molecular cloning of cDNAs derived from a novel human intestinal mucin gene.	MUC3B MUC3A	1.68e-05	2	143	2	2393399
Interaction	SMG7 interactions	HIVEP1 RBM33 RC3H1 PLEKHA4 ZNF318 BCL9 CREBBP KIAA0753 FASN RBM12 LATS1 FUBP3 PRRC2A	3.64e-07	319	140	13	int:SMG7
Interaction	KLF5 interactions	HIVEP1 EP400 BCL9 CREBBP AR TFE3 KMT2C FUBP3 PRRC2A EP300	1.10e-06	195	140	10	int:KLF5
Interaction	SP7 interactions	HIVEP1 EP400 RBM33 ZNF318 BCL9 SSBP3 CREBBP KMT2C RBM12 ZMIZ2 FUBP3 EP300	1.46e-06	304	140	12	int:SP7
Interaction	USP54 interactions	RC3H1 PLEKHA4 OLFM4 BUD13 AR TTC19 LATS1 CLEC11A FUBP3 PRRC2A	2.34e-06	212	140	10	int:USP54
Interaction	GSC interactions	HIVEP1 RREB1 BCL9 CREBBP KMT2C AUTS2 EP300	2.47e-06	87	140	7	int:GSC
Interaction	HNF4A interactions	HIVEP1 EP400 ZNF629 RREB1 CREBBP AR PPARGC1A KMT2C ATXN7 ATF7IP EP300	3.58e-06	275	140	11	int:HNF4A
Interaction	HNF1B interactions	POU6F2 HIVEP1 EP400 BCL9 MBD6 CREBBP KMT2C ATF7IP EP300	7.37e-06	190	140	9	int:HNF1B
Interaction	EYA4 interactions	SF3B4 RBM33 RC3H1 BCL9 SSBP3 CREBBP RBM12 ZMIZ2 AUTS2 EP300	7.87e-06	243	140	10	int:EYA4
Interaction	TLE3 interactions	HIVEP1 CECR2 ZNF318 BCL9 CREBBP AR FAM83H RBM12 ZMIZ2 DZIP3 AUTS2 EP300	1.28e-05	376	140	12	int:TLE3
Interaction	MED23 interactions	EP400 PLEKHA4 CREBBP AR DZIP3 INTS9 PPP1R9B KDF1 BAG6 EP300	1.73e-05	266	140	10	int:MED23
Interaction	SOX7 interactions	CECR2 RREB1 CREBBP KMT2C ZMIZ2 EP300	2.29e-05	82	140	6	int:SOX7
Interaction	PAX7 interactions	HIVEP1 RREB1 BCL9 SSBP3 CREBBP KMT2C EP300	2.57e-05	124	140	7	int:PAX7
Interaction	EGR2 interactions	HIVEP1 EP400 RREB1 BCL9 CREBBP KMT2C ZMIZ2 EP300	2.63e-05	171	140	8	int:EGR2
Interaction	BAG2 interactions	RBM33 RC3H1 PLEKHA4 ZNF318 RREB1 CREBBP PHC1 KIAA0753 TUBGCP6 SHROOM1 PHLPP1 IRF2BPL GREB1 EP300 WDR62	2.88e-05	622	140	15	int:BAG2
Interaction	TLX1 interactions	HIVEP1 RREB1 BCL9 SSBP3 CREBBP KMT2C AUTS2 EP300	3.11e-05	175	140	8	int:TLX1
Interaction	NUP35 interactions	RBM33 RC3H1 PLEKHA4 BCL9 CREBBP FAM83H KMT2C RBM12 AUTS2 FUBP3 MAML3 EP300	4.15e-05	424	140	12	int:NUP35
Interaction	ALG13 interactions	RBM33 RC3H1 BCL9 RBM12 LATS1 FUBP3 PRRC2A EP300	4.27e-05	183	140	8	int:ALG13
Interaction	SEC16A interactions	RC3H1 PLEKHA4 ERN2 AR FAM83H FASN LATS1 PHLPP1 PRKAR2A KDF1 FUBP3 PRRC2A	4.34e-05	426	140	12	int:SEC16A
Interaction	RERE interactions	SETD1B AR FASN AUTS2 PRRC2A EP300	4.69e-05	93	140	6	int:RERE
Interaction	FXR2 interactions	HIVEP1 CECR2 RC3H1 PLEKHA4 OCRL LCP2 LATS1 ZC3H7B FUBP3 PRRC2A INPP5J CCDC33	4.75e-05	430	140	12	int:FXR2
Interaction	MAPK9 interactions	POU6F2 SF3B4 FAM110D PLEKHA4 ZNF414 NFATC3 WDR62 CCDC33	4.79e-05	186	140	8	int:MAPK9
Interaction	ATN1 interactions	HSPG2 SETD1B SIAH2 AR KMT2C AUTS2 PRRC2A BAG6	4.98e-05	187	140	8	int:ATN1
Interaction	ZFHX2 interactions	POU6F2 TFE3 ZFHX2	5.20e-05	11	140	3	int:ZFHX2
Interaction	PIAS3 interactions	SIAH2 CREBBP AR ATF7IP ZMIZ2 EP300	5.28e-05	95	140	6	int:PIAS3
Interaction	C2CD5 interactions	PLEKHA4 PPP6R1 FASN MAPK15 BAG6 EP300	5.28e-05	95	140	6	int:C2CD5
Interaction	AR interactions	HIVEP1 EP400 RBM33 ETV5 SIAH2 DAXX ZNF318 RREB1 BCL9 CREBBP AR KMT2C RBM12 ZMIZ2 IRF2BPL TNS4 FUBP3 BAG6 EP300	5.76e-05	992	140	19	int:AR
Interaction	SELENOP interactions	SELENOP EP400 EP300	6.89e-05	12	140	3	int:SELENOP
Interaction	RBM10 interactions	SF3B4 RC3H1 PLEKHA4 MBD6 GPKOW AR RBM12 LATS1 PHLPP1	7.05e-05	253	140	9	int:RBM10
Interaction	TOP3B interactions	HSPG2 FAM193B SETD1B REPS1 EP400 RBM33 PLEKHA4 SIAH2 PPP6R1 BCL9 MBD6 PLEKHG5 TFE3 FAM83H KMT2C FASN ZMIZ2 PPP1R9B ZC3H7B FUBP3 PRRC2A EP300 CRAMP1 WNK2	7.30e-05	1470	140	24	int:TOP3B
Interaction	TRERF1 interactions	GPKOW CREBBP AR EP300	7.81e-05	33	140	4	int:TRERF1
Interaction	ETV5 interactions	AMH ETV5 AR EP300	7.81e-05	33	140	4	int:ETV5
Interaction	XRN1 interactions	RC3H1 PLEKHA4 KIAA0753 FASN PHLPP1 KDF1 FUBP3 PRRC2A BAG6	8.19e-05	258	140	9	int:XRN1
Interaction	FEV interactions	HIVEP1 EP400 RREB1 BCL9 SSBP3 CREBBP KMT2C EP300	8.86e-05	203	140	8	int:FEV
Interaction	SAV1 interactions	PLEKHA4 FAM83H KIAA0753 LATS1 CLEC11A FUBP3 EP300	9.02e-05	151	140	7	int:SAV1
Interaction	DPY30 interactions	SETD1B MCF2L2 DAXX MBD6 AR TFE3 PHC1 KMT2C	9.16e-05	204	140	8	int:DPY30
Interaction	NCK2 interactions	SF3B4 WIPF1 MBD6 LCP2 FAM83H C4orf17 CASKIN2 PRRC2A CCDC33	9.21e-05	262	140	9	int:NCK2
Interaction	ERI1 interactions	PLEKHA4 FASN SYN1 EP300	9.88e-05	35	140	4	int:ERI1
Interaction	ANKHD1-EIF4EBP3 interactions	DBX2 RC3H1 FAM110D ZNF414 GAS2L2 PRRC2A	1.08e-04	108	140	6	int:ANKHD1-EIF4EBP3
Interaction	INTS4 interactions	PDCD1 AR ZMIZ2 NABP2 INTS9 BTNL9	1.08e-04	108	140	6	int:INTS4
Interaction	GCM1 interactions	HIVEP1 BCL9 CREBBP KMT2C EP300	1.10e-04	68	140	5	int:GCM1
Interaction	HPS6 interactions	PLEKHA4 AR TTC19 EP300	1.11e-04	36	140	4	int:HPS6
Interaction	PAX8 interactions	HIVEP1 BCL9 SSBP3 CREBBP KMT2C EP300	1.26e-04	111	140	6	int:PAX8
Interaction	CNOT11 interactions	FAM193B RC3H1 PLEKHA4 FASN FUBP3 PRRC2A	1.32e-04	112	140	6	int:CNOT11
Interaction	TBR1 interactions	HIVEP1 BCL9 SSBP3 KMT2C LATS1 EP300	1.39e-04	113	140	6	int:TBR1
Interaction	CEBPA interactions	HIVEP1 NEK6 WIPF1 EP400 RBM33 ZNF629 ETV5 ZNF318 RREB1 BCL9 ZNF414 CREBBP AR KMT2C FASN RBM12 ZMIZ2 FUBP3 PRRC2A BAG6 EP300	1.39e-04	1245	140	21	int:CEBPA
Interaction	PHF6 interactions	AMER1 RC3H1 PLEKHA4 DAXX ZNF318 KDF1 EP300	1.40e-04	162	140	7	int:PHF6
Interaction	KDM6A interactions	SETD1B PLEKHA4 ETV5 CREBBP AR TFE3 KMT2C	1.40e-04	162	140	7	int:KDM6A
Interaction	EPG5 interactions	CREBBP ATF7IP BTNL9	1.40e-04	15	140	3	int:EPG5
Interaction	GRB2 interactions	HSPG2 SF3B4 REPS1 WIPF1 RBM33 TOM1L1 PLEKHA4 OCRL LCP2 AR FASN SYN1 ZC3H7B PRRC2A EP300 PLXNB1	1.54e-04	806	140	16	int:GRB2
Interaction	TBXT interactions	HIVEP1 BCL9 SSBP3 CREBBP KMT2C EP300	1.60e-04	116	140	6	int:TBXT
Interaction	CCN2 interactions	HSPG2 CREBBP C4orf17 EP300	1.68e-04	40	140	4	int:CCN2
Interaction	ERG interactions	HIVEP1 BCL9 CREBBP AR KMT2C ATF7IP SYN1 EP300	1.69e-04	223	140	8	int:ERG
Interaction	PUM1 interactions	RC3H1 PLEKHA4 KIAA0753 LATS1 DZIP3 KDF1 FUBP3 PRRC2A EP300	1.83e-04	287	140	9	int:PUM1
Interaction	SUMO1 interactions	PLEKHA4 DAXX CREBBP AR PHC1 ATXN7 PHLPP1 PRRC2A EP300	1.83e-04	287	140	9	int:SUMO1
Interaction	ANKRD17 interactions	DBX2 RC3H1 PLEKHA4 ZNF414 GAS2L2 PHLPP1 FUBP3 PRRC2A	1.86e-04	226	140	8	int:ANKRD17
Interaction	SOX4 interactions	EP400 FASN RP1L1 EP300 PLXNB1	1.87e-04	76	140	5	int:SOX4
Interaction	PCBP2 interactions	RC3H1 PLEKHA4 MBD6 AR TFE3 PPP1R9B KDF1 FUBP3 EP300	1.88e-04	288	140	9	int:PCBP2
Interaction	ETS1 interactions	HIVEP1 EP400 DAXX CREBBP AR EP300	2.02e-04	121	140	6	int:ETS1
Interaction	TIAL1 interactions	SF3B4 PLEKHA4 CREBBP FAM83H DZIP3 FUBP3 PRRC2A	2.02e-04	172	140	7	int:TIAL1
Interaction	TLX3 interactions	POU6F2 HIVEP1 BCL9 SSBP3 AR TFE3 KMT2C ZMIZ2 EP300	2.03e-04	291	140	9	int:TLX3
Interaction	MAML2 interactions	CREBBP FASN EP300	2.08e-04	17	140	3	int:MAML2
Interaction	YWHAH interactions	AMER1 HIVEP1 PLEKHA4 ZNF629 PLEKHG5 CREBBP TFE3 FAM83H KIAA0753 FRMD4A SHROOM1 LATS1 NFATC3 CASKIN2 TBC1D1 PPP1R9B RIMS1 WNK2 WDR62	2.26e-04	1102	140	19	int:YWHAH
Interaction	TEAD1 interactions	HIVEP1 RREB1 SSBP3 CREBBP KMT2C FASN EP300	2.33e-04	176	140	7	int:TEAD1
Interaction	FUBP3 interactions	RBM33 RC3H1 PLEKHA4 AR RBM12 DZIP3 FUBP3 PRRC2A EP300	2.36e-04	297	140	9	int:FUBP3
Interaction	HIPK3 interactions	SIAH2 DAXX CREBBP AR	2.44e-04	44	140	4	int:HIPK3
Interaction	TRIM27 interactions	FAM193B NEK6 PLEKHA4 DAXX GPKOW ZNF414 GAS2L2 ATXN7 TNS4 TTLL10 BAG6 INPP5J	2.53e-04	514	140	12	int:TRIM27
Interaction	TSG101 interactions	TOM1L1 PLEKHA4 DAXX AR FASN DZIP3 IRF2BPL BAG6 EP300	2.73e-04	303	140	9	int:TSG101
Interaction	NR3C2 interactions	DAXX CREBBP AR EP300	2.90e-04	46	140	4	int:NR3C2
Interaction	R3HDM1 interactions	RC3H1 FASN LATS1 FUBP3 PRRC2A	2.99e-04	84	140	5	int:R3HDM1
Interaction	LHX3 interactions	HIVEP1 OCRL BCL9 SSBP3 CREBBP KMT2C GAS2L2	3.16e-04	185	140	7	int:LHX3
Interaction	SMAD4 interactions	NEK6 PLEKHA4 DAXX CREBBP AR TFE3 TUBGCP6 ATF7IP PRKAR2A GREB1 KDF1 EP300	3.34e-04	530	140	12	int:SMAD4
Interaction	YY1 interactions	SF3B4 HIVEP1 EP400 PLEKHA4 MBD6 CREBBP PPARGC1A FASN ATF7IP DZIP3 EP300	3.36e-04	454	140	11	int:YY1
Interaction	TBC1D4 interactions	EP400 PLEKHA4 ZNF414 RBM12 TBC1D1 NABP2	3.64e-04	135	140	6	int:TBC1D4
Interaction	RBM27 interactions	RC3H1 PLEKHA4 AR PHLPP1 KDF1 EP300	3.94e-04	137	140	6	int:RBM27
Interaction	PLAGL1 interactions	DAXX CREBBP EP300	3.98e-04	21	140	3	int:PLAGL1
Interaction	CRX interactions	EP400 RREB1 BCL9 CREBBP KMT2C ATXN7 ZMIZ2 EP300	4.07e-04	254	140	8	int:CRX
Interaction	PCGF3 interactions	PLEKHA4 CREBBP PHC1 DZIP3 AUTS2	4.12e-04	90	140	5	int:PCGF3
Interaction	MYOD1 interactions	HIVEP1 EP400 BCL9 CREBBP PPARGC1A KMT2C EP300	4.20e-04	194	140	7	int:MYOD1
Interaction	KLF12 interactions	HIVEP1 EP400 RREB1 TFE3 FASN ATF7IP EP300	4.20e-04	194	140	7	int:KLF12
Interaction	TNK2 interactions	NEK6 GALT SIAH2 LCP2 AR FRMD4A EP300	4.33e-04	195	140	7	int:TNK2
Interaction	MAPK8 interactions	FAM193B HIVEP1 FAM110D DAXX NFATC3 PHLPP1 EP300 WDR62	4.52e-04	258	140	8	int:MAPK8
Interaction	FOXI1 interactions	BCL9 CREBBP KMT2C FASN EP300	4.56e-04	92	140	5	int:FOXI1
Interaction	HES6 interactions	SSBP3 CREBBP TUBGCP6 EP300	4.66e-04	52	140	4	int:HES6
Interaction	NFIB interactions	HIVEP1 BCL9 SSBP3 CREBBP AR KMT2C	4.76e-04	142	140	6	int:NFIB
Interaction	GATA2 interactions	HIVEP1 BCL9 SSBP3 CREBBP KMT2C FASN EP300	4.89e-04	199	140	7	int:GATA2
Interaction	SF3B5 interactions	SF3B4 MCF2L2 PLEKHA4 OCRL LATS1 PHLPP1	4.95e-04	143	140	6	int:SF3B5
Interaction	RING1 interactions	PLEKHA4 PHC1 KMT2C LATS1 AUTS2 PPP1R9B EP300	5.19e-04	201	140	7	int:RING1
Interaction	NCOA6 interactions	SETD1B CREBBP AR PPARGC1A KMT2C EP300	5.32e-04	145	140	6	int:NCOA6
Interaction	ELF3 interactions	CECR2 CREBBP AR EP300	5.39e-04	54	140	4	int:ELF3
Interaction	IRF5 interactions	HIVEP1 PPP6R1 CREBBP EP300	5.39e-04	54	140	4	int:IRF5
Interaction	PRRC2B interactions	AMER1 CECR2 RC3H1 PLEKHA4 AR CLEC11A FUBP3 PRRC2A	5.39e-04	265	140	8	int:PRRC2B
Interaction	GRIP1 interactions	NEK6 CREBBP AR DZIP3 EP300	5.55e-04	96	140	5	int:GRIP1
Interaction	KIF11 interactions	RC3H1 PLEKHA4 PI4K2A BCL9 FASN LATS1 PHLPP1 EP300	5.66e-04	267	140	8	int:KIF11
Interaction	TPX2 interactions	PLEKHA4 BUD13 SIAH2 AR PHLPP1 PRRC2A EP300	5.67e-04	204	140	7	int:TPX2
Interaction	SUPT5H interactions	HIVEP1 WIPF1 EP400 RBM33 PLEKHA4 SSBP3 NABP2 INTS9 MAML3 EP300	5.75e-04	408	140	10	int:SUPT5H
Interaction	SPINDOC interactions	RC3H1 PLEKHA4 LATS1 ASB2	5.78e-04	55	140	4	int:SPINDOC
Interaction	CIITA interactions	EP400 SSBP3 CREBBP EP300	5.78e-04	55	140	4	int:CIITA
Interaction	KCTD5 interactions	FAM193B NEK6 RC3H1 FASN EP300	5.81e-04	97	140	5	int:KCTD5
Interaction	SOX9 interactions	EP400 BCL9 CREBBP KMT2C EP300	5.81e-04	97	140	5	int:SOX9
Interaction	JUP interactions	PLEKHA4 MBD6 CREBBP AR TFE3 FASN LATS1 PHLPP1 PPP1R9B EP300 CDH15	5.85e-04	485	140	11	int:JUP
Cytoband	7q22	MUC3B MOSPD3 MUC3A	2.30e-04	38	143	3	7q22
GeneFamily	Zinc fingers CCCH-type	RC3H1 ZC3H12B ZC3H6 ZC3H7B	2.91e-05	35	92	4	73
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	DRP2 CREBBP EP300	9.84e-05	18	92	3	91
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD8-Tem/emra_CD8\|GI_large-bowel / Manually curated celltypes from each tissue	AMER1 OLFM4 OCRL SSBP3 ERN2 SYN1 INPP5J	1.07e-06	166	142	7	13bef304ea3df8e8d2bc376a3287c78220a1b0c6
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	SETD1B RC3H1 KIAA0753 NFATC3 ATF7IP MAML3 PLXNB1	1.07e-06	166	142	7	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	droplet-Lung-LUNG-30m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ONECUT2 CECR2 ETV5 KLHDC7A NXPH3 PLXNB1 CCDC33	1.59e-06	176	142	7	5201f003192c033655ba47f0faf8c47a96eae03d
ToppCell	droplet-Lung-LUNG-1m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRP2 PLEKHA4 BEND4 FAM83H PPARGC1A KDF1 PLXNB1	2.29e-06	186	142	7	e52cf44989c57c433bf82e9fa13b4643e88f3577
ToppCell	droplet-Lung-LUNG-1m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRP2 PLEKHA4 BEND4 FAM83H PPARGC1A KDF1 PLXNB1	2.29e-06	186	142	7	4c0b59d845b79323e7a3287e7c4d249f5f322556
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SELENOP WIPF1 CECR2 CAPN3 RIN2 PHLPP1 PLXNB1	2.73e-06	191	142	7	2b056cbe2e82e056e1f798974999378460eb1d16
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PI4K2A GPKOW PRB4 WNK2 TECPR1 CCDC33	6.66e-06	143	142	6	92ddc3e3f6ba78dd9daeb272c12503ec2650a874
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 WIPF1 STXBP5 LCP2 TBC1D1 PHLPP1	2.10e-05	175	142	6	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	droplet-Fat-Gat-18m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM110D ZNF629 PLEKHG5 TUBGCP6 SHROOM1 BTNL9	2.38e-05	179	142	6	08cf9986804a6417a9afb19b50c69a3554f71ec6
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SETD1B FAM110D FRMPD1 MCF2L2 KLHDC7A	2.40e-05	107	142	5	410b37beffaf637a2a64c9d0ce7baf81f4bc667c
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SETD1B FAM110D FRMPD1 MCF2L2 KLHDC7A	2.40e-05	107	142	5	5bae4b3aede9bcbf7e88414e3453973cc8b0c3e7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CECR2 OLFM4 ERN2 SHROOM1 TNS4 WNK2	2.62e-05	182	142	6	678eadd57e7e830fc2bf9fd35616d3badce01705
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CECR2 OLFM4 ERN2 SHROOM1 TNS4 WNK2	2.62e-05	182	142	6	8d1229fa5aa6e2e38f2ac6fe4f4dc89752fe9344
ToppCell	10x5'-Lung-Lymphocytic_Invariant-Inducer-like-ILC3\|Lung / Manually curated celltypes from each tissue	AMER1 TOM1L1 SSBP3 DZIP3 IRF2BPL TTLL10	3.05e-05	187	142	6	0e7aa481effdd8c2fbdf8b65852821dec2d92cde
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SELENOP WIPF1 CECR2 CAPN3 PHLPP1 PLXNB1	3.14e-05	188	142	6	60242c29c7f16c94a84685d3bc4ed93a66e70152
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SELENOP CECR2 CAPN3 RIN2 PHLPP1 PLXNB1	3.23e-05	189	142	6	784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	WIPF1 CECR2 CAPN3 RREB1 RIN2 PLXNB1	3.23e-05	189	142	6	42ab4cc5fbf8580841f31889446fe4499df1a464
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SELENOP CECR2 CAPN3 RIN2 PHLPP1 PLXNB1	3.33e-05	190	142	6	07f21386ea6eb23416a537d2250e3042efe93fb0
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SELENOP CECR2 CAPN3 RIN2 PHLPP1 PLXNB1	3.33e-05	190	142	6	ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 RASGRF2 CASKIN2 TBC1D1 RIN2 BTNL9	3.53e-05	192	142	6	3259cb89d6bcf0a3c6ff1f64d85e8a1f54124e91
ToppCell	facs-Thymus-nan-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP6R1 ARSI KMT2C RBM12 NFATC3 ATF7IP	3.74e-05	194	142	6	f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCell	facs-Thymus-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP6R1 ARSI KMT2C RBM12 NFATC3 ATF7IP	3.74e-05	194	142	6	cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	AMER1 PLEKHA4 SSBP3 PPARGC1A FRMD4A TBC1D1	4.19e-05	198	142	6	f261a37dd07976548b897af86df1d1a0dc069889
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DRP2 ERN2 PLEKHG4B TNS4 RIMS1 WNK2	4.19e-05	198	142	6	1fe60443c11d34b6d2671af8f06e0dedc8d1558b
Drug	Timolol maleate salt [26921-17-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A	ONECUT2 AMH ETV5 TMEM62 CASKIN2 CLEC11A ZMIZ2 ZFHX2 INTS9 GREB1 ZC3H7B	3.23e-08	196	138	11	6483_DN
Drug	Paclitaxel [33069-62-4]; Up 200; 4.6uM; MCF7; HT_HG-U133A	RTL10 ZNF318 BCL9 ERN2 TBC1D1 CLEC11A DZIP3 GREB1 ZC3H7B	3.18e-06	196	138	9	5320_UP
Drug	radicicol; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	FAM193B HIVEP1 RTL10 ZNF318 BCL9 ZMIZ2 ZC3H7B PRRC2A	2.14e-05	190	138	8	836_DN
Drug	Triamcinolone [124-94-7]; Up 200; 10.2uM; PC3; HT_HG-U133A	POU6F2 PI4K2A RTL10 ETV5 RREB1 CASKIN2 ZFHX2 ZC3H7B	2.39e-05	193	138	8	2078_UP
Drug	Xylazine [7361-61-7]; Up 200; 18.2uM; PC3; HT_HG-U133A	CREBBP AR FASN NFATC3 CES3 AUTS2 PRKAR2A TNS4	2.67e-05	196	138	8	4066_UP
Drug	Tranexamic acid [1197-18-8]; Down 200; 25.4uM; MCF7; HT_HG-U133A	ONECUT2 RTL10 ERN2 AR TMEM62 GREB1 FAM174C PRRC2A	2.67e-05	196	138	8	6238_DN
Drug	Fluorocurarine chloride [22273-09-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A	WIPF1 PI4K2A ETV5 ERN2 CES3 AUTS2 ZC3H7B WDR62	2.87e-05	198	138	8	6083_DN
Drug	Pentetic acid [67-43-6]; Up 200; 10.2uM; MCF7; HT_HG-U133A	SETD1B WIPF1 ETV5 ERN2 ZFHX2 ZC3H7B DMRT1 INPP5J	2.98e-05	199	138	8	5264_UP
Drug	Karakoline [39089-30-0]; Down 200; 10.6uM; PC3; HT_HG-U133A	OCRL ERN2 CASKIN2 ZMIZ2 NABP2 DZIP3 PLXNB1 WDR62	2.98e-05	199	138	8	4297_DN
Drug	Fluorometholone [426-13-1]; Down 200; 10.6uM; MCF7; HT_HG-U133A	ONECUT2 PI4K2A ERN2 RIN2 DZIP3 AUTS2 PHLPP1 ZC3H7B	3.08e-05	200	138	8	6071_DN
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	2.24e-05	2	140	2	180849
Disease	Rubinstein-Taybi syndrome due to CREBBP mutations	CREBBP EP300	2.24e-05	2	140	2	cv:C4551859
Disease	Menke-Hennekam syndrome	CREBBP EP300	2.24e-05	2	140	2	cv:C5681632
Disease	Rubinstein-Taybi syndrome (implicated_via_orthology)	CREBBP EP300	2.24e-05	2	140	2	DOID:1933 (implicated_via_orthology)
Disease	Rubinstein-Taybi syndrome	CREBBP EP300	2.24e-05	2	140	2	cv:C0035934
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	2.24e-05	2	140	2	C4551859
Disease	Rubinstein-Taybi syndrome (is_implicated_in)	CREBBP EP300	2.24e-05	2	140	2	DOID:1933 (is_implicated_in)
Disease	Rubinstein-Taybi Syndrome	CREBBP EP300	2.24e-05	2	140	2	C0035934
Disease	Germ Cell Cancer	PHC1 ATF7IP DMRT1	4.56e-05	15	140	3	C0740345
Disease	Embryonal Neoplasm	PHC1 ATF7IP DMRT1	4.56e-05	15	140	3	C0027654
Disease	Neoplasms, Germ Cell and Embryonal	PHC1 ATF7IP DMRT1	4.56e-05	15	140	3	C0027658
Disease	Germ cell tumor	PHC1 ATF7IP DMRT1	4.56e-05	15	140	3	C0205851
Disease	Neoplasms, Embryonal and Mixed	PHC1 ATF7IP DMRT1	4.56e-05	15	140	3	C0205852
Disease	Cancer, Embryonal	PHC1 ATF7IP DMRT1	4.56e-05	15	140	3	C0751364
Disease	Cancer, Embryonal and Mixed	PHC1 ATF7IP DMRT1	4.56e-05	15	140	3	C0751365
Disease	diacylglycerol 33:1 measurement	APOA5 BUD13	1.33e-04	4	140	2	EFO_0020056
Disease	response to steroid, systemic lupus erythematosus, idiopathic osteonecrosis of the femoral head	RREB1 FRMD4A	1.33e-04	4	140	2	EFO_0020976, EFO_1001930, MONDO_0007915
Disease	Primary microcephaly	PHC1 TUBGCP6 WDR62	1.51e-04	22	140	3	C0431350
Disease	RS-10-hydroxywarfarin to RS-warfarin ratio measurement	SELENOP MUC3B MCF2L2 RIN2 MUC3A	1.84e-04	110	140	5	EFO_0803335
Disease	apolipoprotein A-IV measurement	APOA5 SHROOM1	2.21e-04	5	140	2	EFO_0007848
Disease	linoleoyl-linoleoyl-glycerol (18:2/18:2) [1] measurement	APOA5 BUD13	2.21e-04	5	140	2	EFO_0800510
Disease	diacylglycerol 44:6 measurement	APOA5 BUD13	2.21e-04	5	140	2	EFO_0020070
Disease	diacylglycerol 36:1 measurement	APOA5 BUD13	3.31e-04	6	140	2	EFO_0010354
Disease	Tumor of Rete Testis	ATF7IP DMRT1	3.31e-04	6	140	2	C1720811
Disease	Malignant neoplasm of testis	ATF7IP DMRT1	4.62e-04	7	140	2	C0153594
Disease	diacylglycerol 34:0 measurement	APOA5 BUD13	4.62e-04	7	140	2	EFO_0020058
Disease	obesity (implicated_via_orthology)	CAPN3 ETV5 AR PPARGC1A ZFHX2 PLXNB1	5.82e-04	215	140	6	DOID:9970 (implicated_via_orthology)
Disease	triglyceride measurement, metabolic syndrome	APOA5 BUD13	6.14e-04	8	140	2	EFO_0000195, EFO_0004530
Disease	Testicular Neoplasms	ATF7IP DMRT1	6.14e-04	8	140	2	C0039590
Disease	triglyceride measurement, blood pressure	APOA5 BUD13	7.87e-04	9	140	2	EFO_0004325, EFO_0004530
Disease	diacylglycerol 36:4 measurement	APOA5 BUD13	7.87e-04	9	140	2	EFO_0020063
Disease	prostate cancer (is_marker_for)	DAXX AR KMT2C PHLPP1 EP300	9.10e-04	156	140	5	DOID:10283 (is_marker_for)
Disease	Carcinoma, Transitional Cell	CREBBP KMT2C EP300	9.77e-04	41	140	3	C0007138
Disease	diacylglycerol 32.2 measurement	APOA5 BUD13	9.81e-04	10	140	2	EFO_0020055
Disease	Squamous cell carcinoma of esophagus	CREBBP KMT2C FASN EP300	1.11e-03	95	140	4	C0279626
Disease	heart rate response to exercise	MUC3B RP1L1 MUC3A	1.12e-03	43	140	3	EFO_0009184
Disease	systemic lupus erythematosus (implicated_via_orthology)	PDCD1 RC3H1 EP300	1.12e-03	43	140	3	DOID:9074 (implicated_via_orthology)
Disease	diacylglycerol 34:3 measurement	APOA5 BUD13	1.20e-03	11	140	2	EFO_0020059
Disease	Adenoid Cystic Carcinoma	CREBBP KMT2C MAML3 EP300	1.34e-03	100	140	4	C0010606
Disease	beta-endorphin measurement	APOA5 BUD13	1.43e-03	12	140	2	EFO_0008034
Disease	sterol measurement	APOA5 BUD13	1.68e-03	13	140	2	EFO_0010231
Disease	triglyceride measurement, high density lipoprotein cholesterol measurement	APOA5 CAPN3 BUD13 SERPINA11 RP1L1 KDF1	2.02e-03	274	140	6	EFO_0004530, EFO_0004612
Disease	free androgen index	ZNF318 RREB1 AR ZNF469 ZIC5 GREB1 KDF1	2.11e-03	374	140	7	EFO_0007005
Disease	IGFBP-3 measurement	CREBBP MAPK15 GREB1	2.17e-03	54	140	3	EFO_0004626
Disease	body weights and measures, body height	SF3B4 FUBP3	2.25e-03	15	140	2	EFO_0004324, EFO_0004339
Disease	Autosomal recessive primary microcephaly	PHC1 WDR62	2.25e-03	15	140	2	cv:C3711387
Disease	unipolar depression, autism spectrum disorder	OLFM4 BEND4	2.25e-03	15	140	2	EFO_0003756, EFO_0003761
Disease	Diffuse Large B-Cell Lymphoma	CREBBP CCDC86 EP300	2.29e-03	55	140	3	C0079744
Disease	neuroimaging measurement, brain volume measurement	REPS1 SSBP3 PPARGC1A LATS1 PPP1R9B WNK2	2.50e-03	286	140	6	EFO_0004346, EFO_0006930
Disease	cholesteryl ester 16:1 measurement	APOA5 BUD13	2.57e-03	16	140	2	EFO_0010342
Disease	diacylglycerol 36:2 measurement	APOA5 BUD13	2.57e-03	16	140	2	EFO_0010355
Disease	diabetic retinopathy (implicated_via_orthology)	PPARGC1A EP300	2.57e-03	16	140	2	DOID:8947 (implicated_via_orthology)
Disease	diacylglycerol 44:7 measurement	APOA5 BUD13	2.57e-03	16	140	2	EFO_0020069
Disease	proprotein convertase subtilisin/kexin type 7 measurement	APOA5 BUD13	2.90e-03	17	140	2	EFO_0008270
Disease	diacylglycerol 36:3 measurement	APOA5 BUD13	3.25e-03	18	140	2	EFO_0020062
Disease	Hypertriglyceridemia	APOA5 BUD13	3.63e-03	19	140	2	EFO_0004211
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	ADAMTS13 PPARGC1A FASN	3.68e-03	65	140	3	DOID:0080208 (biomarker_via_orthology)
Disease	very low density lipoprotein cholesterol measurement, lipid measurement	APOA5 CAPN3 RBM12 TBC1D1 KDF1	4.07e-03	220	140	5	EFO_0004529, EFO_0008317
Disease	depressive symptom measurement	POU6F2 HIVEP1 OLFM4 BEND4 PPARGC1A PRKAR2A MAML3	4.33e-03	426	140	7	EFO_0007006
Disease	social deprivation, COVID-19	CECR2 RIN2	4.42e-03	21	140	2	EFO_0009696, MONDO_0100096
Disease	Bladder Neoplasm	CREBBP KMT2C MAPK15 EP300	4.52e-03	140	140	4	C0005695
Disease	Malignant neoplasm of urinary bladder	CREBBP KMT2C MAPK15 EP300	4.64e-03	141	140	4	C0005684
Disease	smoking cessation	RBM33 BEND4 ZMIZ2 AUTS2 ZC3H7B MAML3	4.66e-03	325	140	6	EFO_0004319

Protein segments in the cluster

Peptide	Gene	Start	Entry
PRRPHPAPGPGDSNI	TMEM62	41	Q0P6H9
TPHHTPPSIGAQQPP	EP300	841	Q09472
PGPQSQALHPPPRQT	EP300	871	Q09472
GQPPPQPQAPSHAAG	EP400	1566	Q96L91
DSPDPSPPRRPQHNS	BUD13	196	Q9BRD0
PPGPAPGHPQRFSEQ	BTNL9	356	Q6UXG8
TPGAPQHQLPPVPGS	CCDC86	146	Q9H6F5
RHAPSGNQQPPVHPP	CXorf49;	456	A8MYA2
HVHRGPQPPVSDSPP	CCDC33	191	Q8N5R6
PAGPTPAPETNAPNH	BAG6	256	P46379
PAPETNAPNHPSPAE	BAG6	261	P46379
GEQPSAAPPQPPHII	ARSI	36	Q5FYB1
GNGPHPPAPQPSSRF	ASB2	511	Q96Q27
PAPPHKPPNTRENNS	AFF2	886	P51816
GHLRTPAQPPPASPA	BEND4	111	Q6ZU67
SANPPAQRPDPAHPG	RTL10	306	Q7L3V2
PAPVQSPRPQSQPPH	CREBBP	2346	Q92793
SQPPHSSPSPRIQPQ	CREBBP	2356	Q92793
RPEHPQPQPTHYGPS	AMER1	1091	Q5JTC6
PPPPGHSAFAPEFQQ	APOA5	316	Q6Q788
SAGHRLQPPPVPAPS	CECR2	866	Q9BXF3
LHPQGSPSGPPASQP	CECR2	1236	Q9BXF3
QPGPSHPLPNAASPG	DAXX	21	Q9UER7
PRPQPGSAGHPPDAQ	ADAMTS13	286	Q76LX8
GPSGQTHPPPQTLPR	RBM12	396	Q9NTZ6
PVNPHSIPPRGPADL	RC3H1	551	Q5TC82
PQHTPGPVPNSFSQP	RBM33	426	Q96EV2
LHSARPGAPPPQPLD	HSPG2	4361	P98160
QHNCSRQGPTAPPPP	HJV	116	Q6ZVN8
HLLQPPPRPAQPTSG	INTS9	551	Q9NV88
QNPAHEPSPGAPAPQ	GOLGA8F;	346	Q08AF8
NNLPAHPGPASQPPV	MBD6	276	Q96DN6
SSGSPPQPRHPIQPS	MBD6	446	Q96DN6
PQPRHPIQPSLPGTT	MBD6	451	Q96DN6
QPNSAPAHLPLNPPR	KMT2C	3336	Q8NEZ4
PPEGPVQSPLHSPQS	MAGEC1	651	O60732
PNQAHTPGQAPPRPG	MAML3	421	Q96JK9
ETNGPPNPFQLHPLP	GREB1	71	Q4ZG55
AHPSNGQRVNPPPPP	LATS1	226	O95835
PPPAVTNGSQPGAPH	FAM174C	41	Q9BVV8
PRPRPQSSPGHDPAE	MAPK15	386	Q8TD08
PQPRPSAPQVLAHPF	ERN2	766	Q76MJ5
TRPVQPVAPHPESSP	MCF2L2	531	Q86YR7
PPLGPHSNRTTPPES	IRF2BPL	601	Q9H1B7
VPTAHPSPSPRPAGQ	PDCD1	151	Q15116
HEEPSPPSPQNGPGT	PLXNB1	756	O43157
PQLASPAPGHRENAP	MUC3A	61	Q02505
FGQSPFSQPPAPPHQ	FUBP3	436	Q96I24
GSLRGPPPPPTAHQE	ONECUT2	76	O95948
PPPPPTAHQELGTAA	ONECUT2	81	O95948
APQTHRASEPPPPNS	AUTS2	996	Q8WXX7
LGPVHPPDPQRHPNT	NEK6	21	Q9HC98
NGHRRQPPARPPGPS	GPKOW	76	Q92917
APAAKGSPQPEPHAP	MFSD2B	6	A6NFX1
AEPNTPRPQQSPPGH	TUBGCP6	1286	Q96RT7
PAPHSLPEPGPQQQT	ETV5	176	P41161
PAHGQLDTVPFPPPR	AMH	261	P03971
NPGPRHPEAASAAPP	AR	36	P10275
PRPGAGSLQHAQPPP	PDPK2P	31	Q6A1A2
SAAAPHPAPDRPPRQ	IQSEC3	101	Q9UPP2
PAPPRTSQEPHQNPH	ATXN7	416	O15265
GFSRTPQPPAEEPPH	CASKIN2	366	Q8WXE0
HSPSQPDAAQPPKPA	DZIP3	1106	Q86Y13
NHSPPAPRHGPVPAE	RIMS1	446	Q86UR5
PPTTPPHKANQDNPF	PPARGC1A	296	Q9UBK2
PSPPGSPGHDRERQP	PI4K2A	46	Q9BTU6
PPSHNRPPPPQSLEG	FRMD4A	576	Q9P2Q2
QNPAHEPSPGAPAPQ	GOLGA8DP	346	Q0D2H9
APPNSPTGHHPQPAS	FAM193B	246	Q96PV7
TPRLQPPAPHDPATA	DBX2	51	Q6ZNG2
PVTGTEQIPPHPPRD	FRMPD1	1166	Q5SYB0
PLESSPQPPEGLQPH	GAS2L2	851	Q8NHY3
ALQPDAPSPGPSDHP	GALT	101	P07902
SPPQQVPFPHNGPSG	BCL9	1146	O00512
PNGAKVPPRPHSEPS	C4orf17	101	Q53FE4
PQAPSPPQGSPQDQH	CRAMP1	66	Q96RY5
SGSTQRQPPPPAPQH	FBXO28	26	Q9NVF7
PAPQHPQPGSQALPA	FBXO28	36	Q9NVF7
HPPNPPVSPGKTVND	ATF7IP	666	Q6VMQ6
SNPDPPHFPRLGSEP	KLHDC7A	151	Q5VTJ3
PAATPRQSLGHPPPE	PRKAR2A	51	P13861
AVPAPSPGPTHNSPE	FAM83H	1056	Q6ZRV2
AQPPLGPDRFSAPHP	CES3	66	Q6UWW8
PNTQPPPAPAPHATL	FASN	406	P49327
EPRSPGPVPHPAQSK	CAPN3	16	P20807
ETVAAPPGPQSPEHP	C4orf54	1541	D6RIA3
VNDHAPVLAPPPPGS	CDH15	476	P55291
PAQPPPPSRETVGHL	PRSS51	186	A0A1B0GVH4
PHPQVRAAVTSPAPP	DRP2	36	Q13474
STPSEAPHAPGVPPQ	DMRT1	11	Q9Y5R6
NQSQGPPPHPGKPER	PRB4	171	P10163
QPPNRPNHSPPPSAK	NXPH3	81	O95157
PQLASPAPGHRENAP	MUC3B	61	Q9H195
ARPPASPSPQRQAGP	SYN1	546	P17600
FQGPPGSQPSPHAQP	SSBP3	121	Q9BWW4
PSNQSLPPLPSNHPA	TOM1L1	416	O75674
PQPSQAPGPAVHRPV	REPS1	591	Q96D71
PTAAHPPQPGPQGSA	SUPT20HL1	651	Q3ZLR7
PPHTEPDSPSPVLQG	PLEKHA4	501	Q9H4M7
QSPAASPPPHTGQIP	RASGRF2	771	O14827
QASQTHPPFPVGPQP	POU6F2	81	P78424
QHQQGSAPPTPVPPS	PRRC2A	666	P48634
PQPQHTPSPAAPPAA	SIAH2	21	O43255
SPPDPHASQGPPASV	SHROOM1	401	Q2M3G4
TQPHVVFPPSPQPHG	SPATA31E1	236	Q6ZUB1
HQQPPPQPGPSGERR	SETD1B	11	Q9UPS6
HNGVPPSPDRAPPSR	KDF1	131	Q8NAX2
TVPNSPPTHDPGLQP	KIAA0753	186	Q2KHM9
GSNPQPIPPQSHPST	STXBP5	571	Q5T5C0
DQNTPVVHPPPTPGS	OLFM4	231	Q6UX06
TPHPCNELGPPASPR	FAM110D	51	Q8TAY7
SQNQPTGIHREPPPP	OCRL	166	Q01968
TGIHREPPPPPFSVN	OCRL	171	Q01968
NQQPGAPNAPTHPAP	SELENOP	226	P49908
PSASPHPLSPDQPNG	CLEC11A	276	Q9Y240
PAPRPLPASEGHLQP	INPP5J	241	Q15735
PRVQPEPPPGVSAQH	PLEKHG5	966	O94827
PGPEVQVPPSRVAPH	TTC19	36	Q6DKK2
PNLPPPHRPLSSDGV	RIN2	221	Q8WYP3
HAQSPAPPPPPALDR	ZNF414	201	Q96IQ9
SPPGPQFQGSSPHPQ	ZC3H6	456	P61129
EPPTHGPEPTPSRDQ	ZFHX2	1071	Q9C0A1
NAPHQQPPAPPSDAL	TFE3	486	P19532
SNPPVGPAPGRHPQD	RP1L1	281	Q8IWN7
QNGFLHRGPTQPPPP	RREB1	866	Q92766
QGPQPPRHQLSEPAP	SERPINA11	31	Q86U17
PEPGSSPPQRTPGHQ	TNS4	381	Q8IZW8
NPSGPSDVPARQPHP	PLEKHG4B	156	Q96PX9
RPNTHPGPAPTPAEL	TECPR1	471	Q7Z6L1
RSQPNHTPAGPPGPS	NABP2	181	Q9BQ15
SPRPNPPHAAPTGSQ	TBC1D1	211	Q86TI0
PPAGTPPPTARHFQE	MOSPD3	156	O75425
PSLPVPHPAQTQRPS	NFATC3	716	Q12968
GSAAEPARGPPPQHP	TTC14	36	Q96N46
PRPIQSSPHNRGSPP	WIPF1	191	O43516
PNTAPPTPELHGINP	PHC1	916	P78364
QLAPSPHNGTPEPPR	PRR33	36	A8MZF0
PHNGTPEPPRTAPEV	PRR33	41	A8MZF0
PPNIHPGATPQPGRA	ZC3H12B	681	Q5HYM0
HTGPPAPQGPLSVPQ	PPP6R1	736	Q9UPN7
PGPQLHHSNPPPASR	ZMIZ2	831	Q8NF64
SPGHPSQPPLEDNTP	ZNF469	26	Q96JG9
AQPQVSPHGTPSLPP	ZNF469	566	Q96JG9
IPEQPPPSRHDTGTP	ZNF469	1236	Q96JG9
PGPDPQSRGAPPHTN	ZNF469	2276	Q96JG9
PESPGLPAHPSNPQL	WDR62	1346	O43379
RPGHPAQPLPLPQTA	PHLPP1	396	O60346
LRRHPEPAQPAPGSP	ZNF142	1306	P52746
PHSGTPQPALGQPAP	WNK2	1521	Q9Y3S1
SVPQNPPTPLGHSNP	ZNF629	71	Q9UEG4
RLHPAPASQPGPCPA	TTLL10	46	Q6ZVT0
PTSQPSNHPVPEPHR	ZNF318	806	Q5VUA4
PANIIPPPHPLRGSQ	HIVEP1	851	P15822
RPHQLFADAPPPPSA	SF3B4	206	Q15427
DHRPPSGAQKPAPSP	ZC3H7B	386	Q9UGR2
QRSGTGSPQHPAPPP	ZIC5	221	Q96T25
PAGRNHSPLPPPQTN	LCP2	201	Q13094
SAQPAPPPHPPSRLQ	PPP1R9B	131	Q96SB3