Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	5-diphosphoinositol pentakisphosphate 1-kinase activity	PPIP5K1 PPIP5K2	1.92e-05	2	88	2	GO:0033857
GeneOntologyMolecularFunction	inositol hexakisphosphate 3-kinase activity	PPIP5K1 PPIP5K2	1.15e-04	4	88	2	GO:0052724
GeneOntologyMolecularFunction	inositol hexakisphosphate 1-kinase activity	PPIP5K1 PPIP5K2	1.15e-04	4	88	2	GO:0052723
GeneOntologyMolecularFunction	triplex DNA binding	DDX11L8 DDX11	1.15e-04	4	88	2	GO:0045142
GeneOntologyMolecularFunction	inositol hexakisphosphate 5-kinase activity	PPIP5K1 PPIP5K2	1.90e-04	5	88	2	GO:0000832
GeneOntologyMolecularFunction	glucokinase activity	HK2 HK3	1.90e-04	5	88	2	GO:0004340
GeneOntologyMolecularFunction	hexokinase activity	HK2 HK3	1.90e-04	5	88	2	GO:0004396
GeneOntologyMolecularFunction	fructokinase activity	HK2 HK3	1.90e-04	5	88	2	GO:0008865
GeneOntologyMolecularFunction	diphosphoinositol pentakisphosphate kinase activity	PPIP5K1 PPIP5K2	1.90e-04	5	88	2	GO:0000829
GeneOntologyMolecularFunction	inositol hexakisphosphate kinase activity	PPIP5K1 PPIP5K2	1.90e-04	5	88	2	GO:0000828
GeneOntologyMolecularFunction	inositol-1,3,4,5,6-pentakisphosphate kinase activity	PPIP5K1 PPIP5K2	1.90e-04	5	88	2	GO:0000827
GeneOntologyMolecularFunction	5'-3' DNA helicase activity	DDX11L8 DDX11	1.03e-03	11	88	2	GO:0043139
GeneOntologyMolecularFunction	inositol phosphate kinase activity	PPIP5K1 PPIP5K2	1.03e-03	11	88	2	GO:0180030
GeneOntologyMolecularFunction	4 iron, 4 sulfur cluster binding	NUBPL DDX11L8 DDX11	1.17e-03	47	88	3	GO:0051539
GeneOntologyMolecularFunction	semaphorin receptor activity	PLXND1 PLXNB1	1.23e-03	12	88	2	GO:0017154
GeneOntologyMolecularFunction	G-quadruplex DNA binding	DDX11L8 DDX11	1.69e-03	14	88	2	GO:0051880
GeneOntologyMolecularFunction	D-glucose binding	HK2 HK3	1.69e-03	14	88	2	GO:0005536
MousePheno	fused right lung lobes	FRAS1 ITGA8 FREM1	3.80e-06	7	68	3	MP:0010977
MousePheno	absent kidney	FRAS1 KIF26B ITGA8 PLXND1 FREM1	5.62e-06	53	68	5	MP:0000520
MousePheno	abnormal branching involved in ureteric bud morphogenesis	FRAS1 KIF26B ITGA8 PLXNB1	6.57e-05	45	68	4	MP:0010981
MousePheno	cryptophthalmos	FRAS1 FREM1	6.97e-05	3	68	2	MP:0005242
MousePheno	abnormal kidney development	FRAS1 KIF26B ITGA8 FREM1 PLXNB1	8.76e-05	93	68	5	MP:0000527
MousePheno	abnormal ureteric bud morphology	FRAS1 KIF26B ITGA8 PLXNB1	1.67e-04	57	68	4	MP:0006032
MousePheno	abnormal urinary system development	FRAS1 KIF26B ITGA8 FREM1 PLXNB1	2.02e-04	111	68	5	MP:0003942
MousePheno	abnormal placenta morphology	RPTOR UBR4 LAMA1 TMEM209 NUBPL NEK9 FKBP4 ST14 DDX11L8 DDX11	2.10e-04	525	68	10	MP:0001711
MousePheno	single kidney	FRAS1 KIF26B ITGA8 FREM1	2.17e-04	61	68	4	MP:0003604
Domain	Laminin_G	EYS COL12A1 FAT3 LAMA1	1.34e-04	58	84	4	IPR001791
Domain	Hexokinase_C	HK2 HK3	1.98e-04	5	84	2	IPR022673
Domain	Hexokinase_N	HK2 HK3	1.98e-04	5	84	2	IPR022672
Domain	Hexokinase_1	HK2 HK3	1.98e-04	5	84	2	PF00349
Domain	Hexokinase_2	HK2 HK3	1.98e-04	5	84	2	PF03727
Domain	HEXOKINASE_2	HK2 HK3	1.98e-04	5	84	2	PS51748
Domain	Hexokinase_BS	HK2 HK3	1.98e-04	5	84	2	IPR019807
Domain	HEXOKINASE_1	HK2 HK3	1.98e-04	5	84	2	PS00378
Domain	Hexokinase	HK2 HK3	2.96e-04	6	84	2	IPR001312
Domain	Acid_Pase_AS	PPIP5K1 PPIP5K2	2.96e-04	6	84	2	IPR033379
Domain	HIS_ACID_PHOSPHAT_2	PPIP5K1 PPIP5K2	4.14e-04	7	84	2	PS00778
Domain	HIS_ACID_PHOSPHAT_1	PPIP5K1 PPIP5K2	4.14e-04	7	84	2	PS00616
Domain	His_Pase_clade-2	PPIP5K1 PPIP5K2	5.50e-04	8	84	2	IPR000560
Domain	His_Phos_2	PPIP5K1 PPIP5K2	5.50e-04	8	84	2	PF00328
Domain	LAM_G_DOMAIN	EYS FAT3 LAMA1	6.61e-04	38	84	3	PS50025
Domain	Calx_beta	FRAS1 FREM1	7.05e-04	9	84	2	IPR003644
Domain	Plexin_cytopl	PLXND1 PLXNB1	7.05e-04	9	84	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXND1 PLXNB1	7.05e-04	9	84	2	IPR013548
Domain	Plexin	PLXND1 PLXNB1	7.05e-04	9	84	2	IPR031148
Domain	Calx-beta	FRAS1 FREM1	7.05e-04	9	84	2	PF03160
Domain	Laminin_G_2	EYS FAT3 LAMA1	7.69e-04	40	84	3	PF02210
Domain	-	EYS COL12A1 FAT3 LAMA1	8.88e-04	95	84	4	2.60.120.200
Domain	EGF-like_dom	FRAS1 EYS FAT3 LAMA1 FBN3 OTOG	9.02e-04	249	84	6	IPR000742
Domain	LamG	EYS FAT3 LAMA1	1.02e-03	44	84	3	SM00282
Domain	Laminin_G_1	EYS LAMA1	1.07e-03	11	84	2	PF00054
Domain	PLipase_C_Pinositol-sp_Y	PLCH1 PLCE1	2.02e-03	15	84	2	IPR001711
Domain	EF-hand_like	PLCH1 PLCE1	2.02e-03	15	84	2	PF09279
Domain	PIPLC_Y_DOMAIN	PLCH1 PLCE1	2.02e-03	15	84	2	PS50008
Domain	PI-PLC_fam	PLCH1 PLCE1	2.02e-03	15	84	2	IPR001192
Domain	PLC_EF-hand-like	PLCH1 PLCE1	2.02e-03	15	84	2	IPR015359
Domain	PI-PLC-Y	PLCH1 PLCE1	2.02e-03	15	84	2	PF00387
Domain	PLCYc	PLCH1 PLCE1	2.02e-03	15	84	2	SM00149
Domain	PI-PLC-X	PLCH1 PLCE1	2.92e-03	18	84	2	PF00388
Domain	PLCXc	PLCH1 PLCE1	2.92e-03	18	84	2	SM00148
Domain	VWC_out	FRAS1 OTOG	3.25e-03	19	84	2	SM00215
Domain	PIPLC_X_DOMAIN	PLCH1 PLCE1	3.25e-03	19	84	2	PS50007
Domain	PLipase_C_PInositol-sp_X_dom	PLCH1 PLCE1	3.25e-03	19	84	2	IPR000909
Domain	His_PPase_superfam	PPIP5K1 PPIP5K2	3.60e-03	20	84	2	IPR029033
Domain	-	PPIP5K1 PPIP5K2	3.60e-03	20	84	2	3.40.50.1240
Domain	EGF	FRAS1 EYS FAT3 LAMA1 FBN3	4.17e-03	235	84	5	SM00181
Pathway	REACTOME_INOSITOL_PHOSPHATE_METABOLISM	PPIP5K1 PPIP5K2 PLCH1 PLCE1	7.30e-05	48	66	4	M26964
Pathway	REACTOME_INOSITOL_PHOSPHATE_METABOLISM	PPIP5K1 PPIP5K2 PLCH1 PLCE1	7.30e-05	48	66	4	MM14589
Pubmed	A genome wide association study of plasma uric acid levels in obese cases and never-overweight controls.	FRAS1 DIP2C F5	6.47e-08	4	89	3	23703922
Pubmed	Mild recessive mutations in six Fraser syndrome-related genes cause isolated congenital anomalies of the kidney and urinary tract.	FRAS1 ITGA8 FREM1	3.22e-07	6	89	3	24700879
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	FRAS1 LAMA1 ITGA8 FREM1	9.06e-07	29	89	4	22613833
Pubmed	The B-box dominates SAP-1-SRF interactions in the structure of the ternary complex.	SRF ELK4	6.48e-06	2	89	2	11406578
Pubmed	Blood group AB and factor V Leiden as risk factors for pre-eclampsia: a population-based nested case-control study.	ABO F5	6.48e-06	2	89	2	19110300
Pubmed	Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases.	PPIP5K1 PPIP5K2	6.48e-06	2	89	2	18981179
Pubmed	Overlapping and divergent localization of Frem1 and Fras1 and its functional implications during mouse embryonic development.	FRAS1 FREM1	6.48e-06	2	89	2	17240369
Pubmed	Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress.	PPIP5K1 PPIP5K2	6.48e-06	2	89	2	17702752
Pubmed	Serum response factor binding sites differ in three human cell types.	SRF ELK4	6.48e-06	2	89	2	17200232
Pubmed	The GOAL study: a prospective examination of the impact of factor V Leiden and ABO(H) blood groups on haemorrhagic and thrombotic pregnancy outcomes.	ABO F5	6.48e-06	2	89	2	18028481
Pubmed	The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis.	PPIP5K1 PPIP5K2	6.48e-06	2	89	2	28126903
Pubmed	Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases.	PPIP5K1 PPIP5K2	6.48e-06	2	89	2	17690096
Pubmed	Sprouty1 haploinsufficiency prevents renal agenesis in a model of Fraser syndrome.	FRAS1 ITGA8 FREM1	7.21e-06	15	89	3	23064016
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NCAPD3 CEP162 RPTOR PLAGL2 PLXND1 PPIP5K2 NCAPH CNOT1 PLXNB1	8.80e-06	529	89	9	14621295
Pubmed	Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.	FRAS1 LAMA1 FREM1	8.86e-06	16	89	3	16880404
Pubmed	A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.	FRAS1 LAMA1 FREM1	1.29e-05	18	89	3	14730302
Pubmed	[Evaluation of Gene Expression of Hexokinases in Colorectal Cancer with the Use of Bioinformatics Methods].	HK2 HK3	1.94e-05	3	89	2	26855992
Pubmed	PPIP5K2 and PCSK1 are Candidate Genetic Contributors to Familial Keratoconus.	PPIP5K1 PPIP5K2	1.94e-05	3	89	2	31852976
Pubmed	Integrative Proteomics and Phosphoproteomics Profiling Reveals Dynamic Signaling Networks and Bioenergetics Pathways Underlying T Cell Activation.	HK2 RPTOR	1.94e-05	3	89	2	28285833
Pubmed	A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q.	ABO F5	1.94e-05	3	89	2	22672568
Pubmed	[ABO/H blood groups and factor V Leiden].	ABO F5	1.94e-05	3	89	2	11998221
Pubmed	AB0 blood group and risk of venous or arterial thrombosis in carriers of factor V Leiden or prothrombin G20210A polymorphisms.	ABO F5	1.94e-05	3	89	2	18387978
Pubmed	Risk of venous thromboembolism and myocardial infarction associated with factor V Leiden and prothrombin mutations and blood type.	ABO F5	1.94e-05	3	89	2	23382263
Pubmed	Generation and Comparative Analysis of an Itga8-CreER T2 Mouse with Preferential Activity in Vascular Smooth Muscle Cells.	SRF ITGA8	1.94e-05	3	89	2	36424917
Pubmed	Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.	DDX11L8 DDX11	1.94e-05	3	89	2	17611414
Pubmed	Hexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibition.	HK2 RPTOR	1.94e-05	3	89	2	24462113
Pubmed	Mammalian ChlR1 has a role in heterochromatin organization.	DDX11L8 DDX11	1.94e-05	3	89	2	21854770
Pubmed	Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex.	SRF ELK4	1.94e-05	3	89	2	11846562
Pubmed	Hemodialysis vascular access thrombosis: The role of factor V Leiden, prothrombin gene mutation and ABO blood groups.	ABO F5	1.94e-05	3	89	2	21070754
Pubmed	Epac2-dependent mobilization of intracellular Ca²+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ε knockout mice.	PLCH1 PLCE1	3.87e-05	4	89	2	21041529
Pubmed	Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism.	HK2 HK3	3.87e-05	4	89	2	25904018
Pubmed	The role of FREM2 and FRAS1 in the development of congenital diaphragmatic hernia.	FRAS1 FREM1	3.87e-05	4	89	2	29618029
Pubmed	Deficiency of FRAS1-related extracellular matrix 1 (FREM1) causes congenital diaphragmatic hernia in humans and mice.	FRAS1 FREM1	3.87e-05	4	89	2	23221805
Pubmed	High 18F-FDG uptake in PMAH correlated with normal expression of Glut1, HK1, HK2, and HK3.	HK2 HK3	3.87e-05	4	89	2	25766729
Pubmed	ABO blood groups and genetic risk factors for thrombosis in Croatian population.	ABO F5	3.87e-05	4	89	2	20017223
Pubmed	Common susceptibility alleles are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach.	ABO F5	3.87e-05	4	89	2	19278955
Pubmed	Frem1 activity is regulated by Sonic hedgehog signaling in the cranial neural crest mesenchyme during midfacial morphogenesis.	FRAS1 FREM1	3.87e-05	4	89	2	36495293
Pubmed	Genome-wide association study indicates two novel resistance loci for severe malaria.	ABO ATP2B4	3.87e-05	4	89	2	22895189
Pubmed	Interaction of ATF6 and serum response factor.	SRF ELK4	3.87e-05	4	89	2	9271374
Pubmed	Differential localization profile of Fras1/Frem proteins in epithelial basement membranes of newborn and adult mice.	FRAS1 FREM1	3.87e-05	4	89	2	18563433
Pubmed	MKL1/2 and ELK4 co-regulate distinct serum response factor (SRF) transcription programs in macrophages.	SRF ELK4	3.87e-05	4	89	2	24758171
Pubmed	Classification of IDH wild-type glioblastoma tumorspheres into low- and high-invasion groups based on their transcriptional program.	SRF IDH1	3.87e-05	4	89	2	37558923
Pubmed	Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis.	NCAPD3 NCAPH	3.87e-05	4	89	2	27737959
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	NCAPD3 FRAS1 HK2 LSG1 PPIP5K2 PLCH1 DDX11L8 PLXNB1 PLCE1	4.43e-05	650	89	9	38777146
Pubmed	Characterization of the endogenous nonecotropic murine leukemia viruses of NZB/B1NJ and SM/J inbred strains.	ETS1 IDH1 TG	6.26e-05	30	89	3	1311971
Pubmed	Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development.	FRAS1 FREM1	6.44e-05	5	89	2	17251066
Pubmed	Novel frem1-related mouse phenotypes and evidence of genetic interactions with gata4 and slit3.	FRAS1 FREM1	6.44e-05	5	89	2	23536828
Pubmed	Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.	FRAS1 FREM1	6.44e-05	5	89	2	17596926
Pubmed	Comparative analysis of the ternary complex factors Elk-1, SAP-1a and SAP-2 (ERP/NET).	SRF ELK4	6.44e-05	5	89	2	7540136
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KIF26B LSG1 CEP162 RPTOR PPIP5K2 PLCH1 NEK9 HDAC7 DENND2B OTOG	7.15e-05	861	89	10	36931259
Pubmed	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.	UIMC1 ABO F5	8.36e-05	33	89	3	22703881
Pubmed	Phospholipase Cε hydrolyzes perinuclear phosphatidylinositol 4-phosphate to regulate cardiac hypertrophy.	PLCH1 PLCE1	9.65e-05	6	89	2	23540699
Pubmed	Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae.	SRF ELK4	9.65e-05	6	89	2	23563308
Pubmed	Craniofacial consequences of connective tissue disorders in mice.	FRAS1 FREM1	9.65e-05	6	89	2	6391574
Pubmed	c-Fos oncogene regulator Elk-1 interacts with BRCA1 splice variants BRCA1a/1b and enhances BRCA1a/1b-mediated growth suppression in breast cancer cells.	ETS1 ELK4	9.65e-05	6	89	2	11313879
Pubmed	Frem3, a member of the 12 CSPG repeats-containing extracellular matrix protein family, is a basement membrane protein with tissue distribution patterns distinct from those of Fras1, Frem2, and QBRICK/Frem1.	FRAS1 FREM1	9.65e-05	6	89	2	17462874
Pubmed	Haemostatic genetic variants, ABO blood group and bleeding risk during oral anticoagulant treatment after cerebral ischaemia of arterial origin.	ABO F5	9.65e-05	6	89	2	17994314
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ESRP2 FRAS1 MROH6 RPTOR UBR4 DIP2C PLXND1 NUBPL ZBED3 HDAC7 ST14	1.20e-04	1105	89	11	35748872
Pubmed	Serum response factor, its cofactors, and epithelial-mesenchymal signaling in urinary bladder smooth muscle formation.	SRF ELK4	1.35e-04	7	89	2	16466398
Pubmed	Temporal Dynamics and Neuronal Specificity of Grin3a Expression in the Mouse Forebrain.	SLC17A7 GRIN3A	1.35e-04	7	89	2	33290502
Pubmed	Genetics of venous thrombosis: insights from a new genome wide association study.	ABO F5	1.35e-04	7	89	2	21980494
Pubmed	Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells.	NCAPD3 NCAPH	1.79e-04	8	89	2	14532007
Pubmed	ABO blood group but not haemostasis genetic polymorphisms significantly influence thrombotic risk: a study of 180 homozygotes for the Factor V Leiden mutation.	ABO F5	1.79e-04	8	89	2	17107352
Pubmed	The ENU-induced cetus mutation reveals an essential role of the DNA helicase DDX11 for mesoderm development during early mouse embryogenesis.	DDX11L8 DDX11	1.79e-04	8	89	2	22678773
Pubmed	Reconstitution and subunit geometry of human condensin complexes.	NCAPD3 NCAPH	1.79e-04	8	89	2	17268547
Pubmed	A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium.	ABO F5	1.79e-04	8	89	2	23650146
Pubmed	Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type prostaglandin D synthase, and granulin precursor with the N-terminal half of type III hexokinase.	HK2 HK3	1.79e-04	8	89	2	11068878
Pubmed	Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisions.	NCAPD3 NCAPH	1.79e-04	8	89	2	25474630
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	ABCA13 RPTOR LAMA1 CNOT1 OTOG	2.01e-04	208	89	5	33230847
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	UIMC1 EYS ETS1 PLAGL2 CNOT1 ST14	2.16e-04	332	89	6	37433992
Pubmed	A protein interaction landscape of breast cancer.	DNAJA3 UIMC1 HK2 LSG1 UBR4 IDH1 ATP2B4 FKBP4	2.25e-04	634	89	8	34591612
Pubmed	Expression of hexokinases and glucose transporters in treated and untreated oesophageal adenocarcinoma.	HK2 HK3	2.30e-04	9	89	2	19554504
Pubmed	Lactate downregulates the glycolytic enzymes hexokinase and phosphofructokinase in diverse tissues from mice.	HK2 HK3	2.30e-04	9	89	2	21074528
Pubmed	A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.	ABO PPIP5K1	2.30e-04	9	89	2	23300138
Pubmed	Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.	UIMC1 HK3	2.30e-04	9	89	2	19448621
Pubmed	Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development.	SRF TG	2.88e-04	10	89	2	18952847
Pubmed	Morphological diversity of single neurons in molecularly defined cell types.	SLC17A7 PLXND1	2.88e-04	10	89	2	34616072
Pubmed	Condensins I and II are essential for construction of bivalent chromosomes in mouse oocytes.	NCAPD3 NCAPH	2.88e-04	10	89	2	21795393
Pubmed	The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.	FRAS1 FREM1	2.88e-04	10	89	2	15345741
Pubmed	Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis.	ABO TG	3.51e-04	11	89	2	23612905
Pubmed	Specificity of sensory-motor connections encoded by Sema3e-Plxnd1 recognition.	SLC17A7 PLXND1	3.51e-04	11	89	2	19421194
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	DNAJA3 NCAPD3 HK2 RPTOR UBR4 TMEM209 CCT6B QPCT CNOT1 NEK9 DDX11	3.64e-04	1257	89	11	37317656
Pubmed	Kinase signalling in excitatory neurons regulates sleep quantity and depth.	SLC17A7 HDAC7	4.20e-04	12	89	2	36477539
Pubmed	Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.	PLXND1 PLXNB1	4.20e-04	12	89	2	21270798
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	PLXND1 PLXNB1	4.96e-04	13	89	2	10520995
Pubmed	Condensin I and II Complexes License Full Estrogen Receptor α-Dependent Enhancer Activation.	NCAPD3 NCAPH	5.78e-04	14	89	2	26166704
Pubmed	An analysis of expression patterns of genes encoding proteins with catalytic activities.	HK2 HK3 IDH1	6.89e-04	67	89	3	17626619
Pubmed	Sall1 balances self-renewal and differentiation of renal progenitor cells.	FRAS1 KIF26B ITGA8	6.89e-04	67	89	3	24550112
Pubmed	Study of 18 functional hemostatic polymorphisms in mucocutaneous bleeding disorders.	ABO F5	7.59e-04	16	89	2	20532885
Pubmed	Rearrangement of genes located on homologous chromosomal segments in mouse and man: the location of genes for alpha- and beta-interferon, alpha-1 acid glycoprotein-1 and -2, and aminolevulinate dehydratase on mouse chromosome 4.	ALAD IFNA8	7.59e-04	16	89	2	3100390
Pubmed	Genetic predictors of fibrin D-dimer levels in healthy adults.	ABO F5	7.59e-04	16	89	2	21502573
Pubmed	Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.	ITGA8 FREM1	7.59e-04	16	89	2	15878328
Pubmed	Linkage analyses using biochemical variants in mice. 3. Linkage relationships of eleven biochemical markers.	ALAD IDH1	7.59e-04	16	89	2	5424503
Pubmed	Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme.	KIF26B ITGA8	7.59e-04	16	89	2	20439720
Pubmed	Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.	PLXND1 PLXNB1	8.59e-04	17	89	2	11683995
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	PLXND1 PLXNB1	8.59e-04	17	89	2	17626059
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	FRAS1 COL12A1 LAMA1 FREM1	9.11e-04	167	89	4	22159717
Pubmed	Network organization of the human autophagy system.	BTBD8 GLG1 RPTOR NEK9 FKBP4 FREM1	9.18e-04	437	89	6	20562859
Pubmed	Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.	PPFIA4 F5 ATP2B4	9.21e-04	74	89	3	19536175
Pubmed	Human immunodeficiency virus-1 glycoproteins gp120 and gp160 specifically inhibit the CD3/T cell-antigen receptor phosphoinositide transduction pathway.	PLCH1 PLCE1	9.65e-04	18	89	2	1979339
GeneFamily	Plexins	PLXND1 PLXNB1	3.00e-04	9	53	2	683
GeneFamily	Phospholipases\|C2 domain containing phospholipases	PLCH1 PLCE1	1.40e-03	19	53	2	832
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000	COL12A1 KIF26B FAT3 LAMA1 ETS1 SRF ITGA8 ALAD IDH1 PPIP5K2 DENND2B ATP2B4 FREM1	1.09e-05	797	82	13	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ONECUT2 FRAS1 COL12A1 ABCA13 KIF26B FAT3 LAMA1 PLCH1 FREM1 OTOG PLCE1	1.10e-13	184	89	11	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ONECUT2 FRAS1 COL12A1 ABCA13 KIF26B FAT3 LAMA1 PLCH1 FREM1 OTOG PLCE1	1.10e-13	184	89	11	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ONECUT2 FRAS1 COL12A1 ABCA13 KIF26B FAT3 LAMA1 PLCH1 FREM1 OTOG PLCE1	1.10e-13	184	89	11	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	frontal_cortex\|World / Per Region, Lineage, Cell class, Cell type, Cell subtype	ONECUT2 COL12A1 FAT3 ETS1 IDH1 PLCH1	6.21e-07	152	89	6	f9c29d4568402ca07a717dbffb3ccc7f35c5fe56
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 TMEM169 COL12A1 FAT3 LAMA1 FREM1	8.38e-07	160	89	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 TMEM169 COL12A1 FAT3 LAMA1 FREM1	8.38e-07	160	89	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAPD3 HK3 ABCA13 SGO2 NCAPH F5	1.72e-06	181	89	6	566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAPD3 HK3 ABCA13 SGO2 NCAPH F5	1.72e-06	181	89	6	db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS COL12A1 KIF26B ETS1 PLCH1 PLCE1	2.01e-06	186	89	6	6379609b7ace80683f5754b16aa77f11b43766ae
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS COL12A1 KIF26B ETS1 PLCH1 PLCE1	2.08e-06	187	89	6	d413fb4b1531b297af5012a392b88128510c2de8
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS KIF26B ETS1 GRIN3A PLCH1 PLCE1	2.28e-06	190	89	6	d19bc44310c53726e2f5f6a2bd377bbbf1d1983f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS COL12A1 KIF26B ETS1 PLCH1 PLCE1	2.42e-06	192	89	6	0003d7ef9a8e521e70ac33c63aad843d9b6215c2
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 KIF26B FAT3 ITGA8 FREM1 PLCE1	2.57e-06	194	89	6	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	(2)_Fibroblasts-(22)_Fibro-3\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	COL12A1 FAT3 ITGA8 QPCT BBS9 FREM1	2.81e-06	197	89	6	d9021bab82403e566ec10f78acb227c0f80b88fe
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 PPFIA4 ITGA8 GRIN3A NCAPH	1.28e-05	150	89	5	8645b9c7f9511ed6cc9afe04440c2873a3094150
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 ETS1 ITGA8 GRIN3A TG	1.80e-05	161	89	5	1b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|343B / Donor, Lineage, Cell class and subclass (all cells)	NCAPD3 HK3 ACSM5 CDT1 TMEM236	2.14e-05	167	89	5	7efa0081e79f22b219eac64ffcaedb2179cde299
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NCAPD3 SGO2 CDT1 NCAPH DDX11	2.27e-05	169	89	5	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	NCAPD3 BTBD8 ACSM5 CDT1 NCAPH	2.47e-05	172	89	5	e9b97f37bb1732ad9aa89c5e9b513d14022801ac
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ESRP2 HK2 ABO CDT1 ST14	2.54e-05	173	89	5	81c36b9fe02c59099f080b2db02f4eaf2783911f
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KIF26B ETS1 PLXND1 DENND2B ATP2B4	3.07e-05	180	89	5	d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BTBD8 ETS1 ITGA8 PLXND1 HDAC7	3.15e-05	181	89	5	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ABCA13 LAMA1 DIP2C ACMSD	3.59e-05	186	89	5	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABO SGO2 CDT1 IDH1 NCAPH	3.77e-05	188	89	5	b3cae49f0665ace0016a6441cbf9ae40755b0ea3
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ONECUT2 BTBD8 LAMA1 SLC17A7 PLCE1	3.77e-05	188	89	5	e239bcdbd210a398a5850cb6fbf171d402f45a4f
ToppCell	(2)_Fibroblasts-(22)_Fibro-3\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	COL12A1 ITGA8 QPCT BBS9 FREM1	3.97e-05	190	89	5	3aed03b87ba2c8d479048c3ceef3ff5e38746c28
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS KIF26B ETS1 PLCH1 PLCE1	3.97e-05	190	89	5	305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS KIF26B ETS1 PLCH1 PLCE1	3.97e-05	190	89	5	8c9c230a509afaeee50644153974a5642b01a2b8
ToppCell	Mild-T/NK_proliferative\|World / Disease group and Cell class	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.07e-05	191	89	5	9dba5526fd5ea8065ad305feb2ee562335f887c6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 KIF26B FAT3 ITGA8 DENND2B	4.07e-05	191	89	5	107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 KIF26B FAT3 ITGA8 DENND2B	4.07e-05	191	89	5	bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS KIF26B ETS1 GRIN3A PLCH1	4.07e-05	191	89	5	782bc7946417549ffd39e5b596db659436fa01ba
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS KIF26B GRIN3A PLCH1 DENND2B	4.27e-05	193	89	5	c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS KIF26B GRIN3A PLCH1 PLCE1	4.27e-05	193	89	5	53bcd50892c379b2a571751f6eb1062436339fe7
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.27e-05	193	89	5	cf680afddc08b6481f1b3eee9c57acfaebeac6f0
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KIF26B ITGA8 GRIN3A PLCH1 FREM1	4.27e-05	193	89	5	8b77625bf3c87d39767fb391d1beaca4ab02342b
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS KIF26B GRIN3A PLCH1 DENND2B	4.27e-05	193	89	5	658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCell	(1)_T_cells_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.38e-05	194	89	5	8f313071933451780309d2174ed27d8cdc734343
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS KIF26B GRIN3A PLCH1 DENND2B	4.38e-05	194	89	5	83863da11dfbe59b2d0a2c08db40b537c150588c
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ABCA13 PPFIA4 FAT3 LAMA1 F5	4.49e-05	195	89	5	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ABCA13 PPFIA4 FAT3 LAMA1 F5	4.49e-05	195	89	5	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	(1)_T_cells-(1)_T_cells_Dividing\|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.49e-05	195	89	5	cf00a0b4f341f0487d5b37810abe2952fdd3f6f2
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.60e-05	196	89	5	9591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCell	severe_COVID-19-T/NK_proliferative\|World / disease group, cell group and cell class (v2)	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.71e-05	197	89	5	189d97a6c2ff8803db8cc05e205c9d88dac3911f
ToppCell	proximal-Hematologic-Proliferating_Macrophage\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NCAPD3 SGO2 CDT1 GRIN3A NCAPH	4.71e-05	197	89	5	0b1fa881abbfcc54b322fc27124db3f8947af016
ToppCell	proximal-3-Hematologic-Proliferating_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NCAPD3 SGO2 CDT1 GRIN3A NCAPH	4.71e-05	197	89	5	0dd9058aa19d1268ebba9a65555870224b5a5978
ToppCell	proximal-Hematologic-Proliferating_Macrophage-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NCAPD3 SGO2 CDT1 GRIN3A NCAPH	4.71e-05	197	89	5	9243617b307acf3df40d93c41cd8d4788699a7ea
ToppCell	severe_COVID-19-T/NK_proliferative\|severe_COVID-19 / disease group, cell group and cell class (v2)	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.83e-05	198	89	5	ed86b0247006befe55400c287d334d2202b470bd
ToppCell	COVID-19_Moderate-T/NK_proliferative\|World / disease group, cell group and cell class	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.83e-05	198	89	5	bf0131fbca6032e1aab4aa807f8c1d3be689cb7f
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.83e-05	198	89	5	6981cd5b1585c8ae6febdf0c4fb83067127f106c
ToppCell	severe_influenza-T/NK_proliferative\|severe_influenza / disease group, cell group and cell class (v2)	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.94e-05	199	89	5	638b1491c47f2884daf1c1d38a779ad8e0f59c52
ToppCell	Fetal_29-31_weeks\|World / Lineage, Cell type, age group and donor	FRAS1 COL12A1 KIF26B FAT3 DIP2C	4.94e-05	199	89	5	5b9d355795dd03a22f0961dfd143425c367a4654
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.94e-05	199	89	5	e98ff036d04fc78dffef156bdc0d644532274067
ToppCell	severe_influenza-T/NK_proliferative\|World / disease group, cell group and cell class (v2)	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.94e-05	199	89	5	1541f655f7d12c650added3683d07e5417a68dfb
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.94e-05	199	89	5	7feedb0bf84a3361c8ab5b6674ff64e8ff140c23
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.94e-05	199	89	5	123fbf2122aa221d8cbf3aef9361ba0982c07695
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.94e-05	199	89	5	6b1304417cf9c44ca70d2bfc2b5acc1a206f25b6
ToppCell	COVID-19_Severe-T/NK_proliferative\|COVID-19_Severe / disease group, cell group and cell class	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.94e-05	199	89	5	af78837f3a7641a5bd98765eef9cb4f86034048c
ToppCell	mild_COVID-19-T/NK_proliferative\|mild_COVID-19 / disease group, cell group and cell class (v2)	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.94e-05	199	89	5	df2fcaf01b1b48632f84e7355ef21d20853f0664
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NCAPD3 SGO2 CDT1 NCAPH DDX11	4.94e-05	199	89	5	616c04b0605907fb218263f2164c36cb2fa26b87
ToppCell	Severe-Lymphoid-T-Proliferating_T\|Severe / Condition, Lineage, Cell class and cell subclass	NCAPD3 ETS1 SGO2 CDT1 NCAPH	5.06e-05	200	89	5	266270c756fb69945449ce02da04743cd31f8158
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1--L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EYS COL12A1 ETS1 PLCH1 PLCE1	5.06e-05	200	89	5	4a426ef88376d8bb2b9dc50aa06e7b9fc50ecc9c
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EYS KIF26B ETS1 PLCH1 PLCE1	5.06e-05	200	89	5	1276bfa911fddada4235e12e3081baa53164574b
ToppCell	control-HLA-DR-_S100A+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HK2 HK3 QPCT IDH1 F5	5.06e-05	200	89	5	107a0665fb20247511a430178effd7630a619488
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NCAPD3 ETS1 SGO2 CDT1 NCAPH	5.06e-05	200	89	5	3c3ac587ad98e3f6be809eac18c7742a23140de1
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NCAPD3 ETS1 SGO2 CDT1 NCAPH	5.06e-05	200	89	5	5c84aaedac9f27da0da0493dab7c8f7a4d66888c
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NCAPD3 ETS1 SGO2 CDT1 NCAPH	5.06e-05	200	89	5	dd7ad295ab3ba4c19babffb1625900db414bb5a9
ToppCell	BL-critical-LOC-Lymphoid-Treg\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NCAPD3 SGO2 CDT1 NCAPH DDX11	5.06e-05	200	89	5	04d95a9102248e98eed069840ea6d3d23a243fd5
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EYS COL12A1 ETS1 PLCH1 PLCE1	5.06e-05	200	89	5	fbeee1c16ac0a7fe28d90491c8b079f21ce80bdc
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EYS COL12A1 ETS1 PLCH1 PLCE1	5.06e-05	200	89	5	c6eda342ea0cb37d71d89dbb8d11e819e0745172
ToppCell	severe-CD163+_Monocytes_(Sample_ID1_d7)\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HK3 QPCT IDH1 F5 ST14	5.06e-05	200	89	5	4943fe826d5fcc3dfeb8b99a7415848f3fecc994
ToppCell	control-HLA-DR-_S100A+_Monocyte\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HK2 HK3 QPCT IDH1 F5	5.06e-05	200	89	5	9e3e13a68bc1110fa000ec2d80f4c654ddbce17e
ToppCell	Neuronal-Inhibitory-iB\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EYS KIF26B GRIN3A PLCH1 PLCE1	5.06e-05	200	89	5	45ddc5ef2caa87ada88327b63ba9b150a6bb3aa5
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	ABO UBR4 ELK4 KLHL20	1.05e-04	122	89	4	1ed865f0ecfe304fb86313ff51c04e9052357270
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Nr2f2_Necab1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ABO KIF26B GRIN3A NCAPH	1.12e-04	124	89	4	298ff8bd8f0459f44ce8a8aea889c6f1cf84ac5f
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 FAT3 PLCH1 DENND2B	1.19e-04	126	89	4	69b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ABCA13 FAT3 PLCH1 DENND2B	1.19e-04	126	89	4	6cb89754010d64875e115da6c5805efac7a4a82d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 DIP2C PLCH1 KLHL32	1.94e-04	143	89	4	7a7a9829ba63468c9745904d9e993590051207ab
ToppCell	MS-CD4-antiviral_CD4\|MS / Condition, Cell_class and T cell subcluster	ABO ZNF233 F5 TG	2.45e-04	152	89	4	b1eba2d5a6da3eeb83d40a92976e3e8751ed18ee
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Lypd1_Gpr88\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FRAS1 FAT3 SLC17A7 PLXND1	2.77e-04	157	89	4	5aee90ad7aaa65fdabc23597451da5e48db8f4e6
ToppCell	390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	SGO2 CDT1 NCAPH DDX11	2.90e-04	159	89	4	0fbfdb18b7ed4bde077add13f2b3636e144b254f
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	MPZL3 KIF26B PPFIA4 ITGA8	2.90e-04	159	89	4	f34f2729a3872fbb2939e76ad35d7e25f71b8f57
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal-Unfolded_protein_responsible_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	MPZL3 KIF26B PPFIA4 ITGA8	2.90e-04	159	89	4	929ed98f6c2ad14e8d5af5c6f11a5a3d4b388cf7
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FAT3 ITGA8 FZD10 FREM1	3.04e-04	161	89	4	b19f82dd98a3064581793711bb70373f18abecd9
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FRAS1 ABCA13 FAT3 F5	3.12e-04	162	89	4	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NCAPD3 CEP162 SGO2 CDT1	3.19e-04	163	89	4	3efbbdc9cb2613bb76d8c2f07cd4ec1a2c51a622
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NCAPD3 SGO2 NCAPH DDX11	3.19e-04	163	89	4	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ABO CDT1 NCAPH DDX11	3.19e-04	163	89	4	aa5ea367f787c1543afb7eb80a801432e1c44011
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PPFIA4 ITGA8 PLXND1 GRIN3A	3.26e-04	164	89	4	b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ESRP2 LAMA1 ACMSD ST14	3.26e-04	164	89	4	ea02ca343b2b28e437304de889e2ae1e315a1197
ToppCell	droplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM209 CCT6B SGO2 DDX11	3.34e-04	165	89	4	96f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HK2 PPFIA4 IDH1 PPIP5K2	3.34e-04	165	89	4	354978d4f35154d7b2e36e94de669e045adef512
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ABO TCP11L1 FAT3 FREM1	3.42e-04	166	89	4	65dafed953b01a9830b54309af75c7a561e88336
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	NCAPD3 BTBD8 ACSM5 CDT1	3.42e-04	166	89	4	f4698fd08965936d51695d571bd10fb77330d916
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 ITGA8 GRIN3A PLXNB1	3.50e-04	167	89	4	4e613be2b3ba01160b0c0254fce3c4f72220e580
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 ITGA8 GRIN3A PLXNB1	3.50e-04	167	89	4	18ad85751bd892309627eefc357eb28ec5a7c300
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF26B CDT1 DENND2B PLCE1	3.58e-04	168	89	4	de0b00bc405c898d08a06b2e585fb62c0ab9a66e
ToppCell	343B-Lymphocytic-NK_cells-Proliferating_NK_cell\|343B / Donor, Lineage, Cell class and subclass (all cells)	NCAPD3 CLDND2 SGO2 NCAPH	3.66e-04	169	89	4	02fa66a91b8bd2bf971aec4f5ec58318b5bfdf14
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITGA8 SGO2 FREM1 DDX11	3.66e-04	169	89	4	563c267edaade0e5df192ad953801ef9768d4270
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 ITGA8 ST14 FREM1	3.66e-04	169	89	4	716e9d4c5fb99c56b76afaa5ed90bfa859fde802
Drug	Dantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; PC3; HT_HG-U133A	TCP11L1 ETS1 SLC17A7 PLXND1 F5 BBS9 HDAC7 TRMT61A	8.88e-07	197	87	8	3786_DN
Drug	Cefmetazole sodium salt [56796-39-5]; Up 200; 8.2uM; HL60; HT_HG-U133A	TCP11L1 SRF SLC17A7 F5 HDAC7 ST14 KLHL20	1.06e-05	197	87	7	2524_UP
Drug	Lincomycin hydrochloride [859-18-7]; Down 200; 9uM; MCF7; HT_HG-U133A	ONECUT2 GLG1 TMEM209 ALAD PLXND1 PLCH1 BBS9	1.10e-05	198	87	7	5992_DN
Disease	level of plexin-D1 in blood serum	ABO PLXND1	7.44e-06	2	81	2	OBA_2042940
Disease	thrombomodulin measurement	ONECUT2 ABO LAMA1	1.32e-05	17	81	3	EFO_0007774
Disease	Warsaw breakage syndrome (implicated_via_orthology)	DDX11L8 DDX11	2.23e-05	3	81	2	DOID:0060535 (implicated_via_orthology)
Disease	Fraser syndrome (implicated_via_orthology)	FRAS1 FREM1	4.45e-05	4	81	2	DOID:0090001 (implicated_via_orthology)
Disease	Congenital absence of kidneys syndrome	ITGA8 FREM1	7.40e-05	5	81	2	C1609433
Disease	response to platinum based chemotherapy, cytotoxicity measurement	FRAS1 EYS	7.40e-05	5	81	2	EFO_0004647, EFO_0006952
Disease	hyperinsulinemic hypoglycemia (implicated_via_orthology)	HK2 HK3	7.40e-05	5	81	2	DOID:13317 (implicated_via_orthology)
Disease	orofacial cleft, sex interaction measurement	COL12A1 ETS1 ST14 PLCE1	9.43e-05	86	81	4	EFO_0008343, MONDO_0000358
Disease	peripheral vascular disease	ABO F5	1.55e-04	7	81	2	EFO_0003875
Disease	Unilateral agenesis of kidney	FRAS1 FREM1	2.06e-04	8	81	2	C0266294
Disease	holoprosencephaly (is_implicated_in)	PLCH1 CNOT1	2.06e-04	8	81	2	DOID:4621 (is_implicated_in)
Disease	hemoglobin measurement, mean corpuscular hemoglobin concentration	ABO CDT1	2.06e-04	8	81	2	EFO_0004509, EFO_0004528
Disease	C-C motif chemokine 25 measurement	ABO FBN3	2.65e-04	9	81	2	EFO_0008050
Disease	3-phenylpropionate hydrocinnamate measurement	LAMA1 ACSM5	3.30e-04	10	81	2	EFO_0021010
Disease	maturity-onset diabetes of the young (implicated_via_orthology)	HK2 HK3	3.30e-04	10	81	2	DOID:0050524 (implicated_via_orthology)
Disease	gastric adenocarcinoma (is_implicated_in)	ABCA13 PLCE1	4.03e-04	11	81	2	DOID:3717 (is_implicated_in)
Disease	optic cup area measurement	ABO FAT3 PLCE1	4.97e-04	56	81	3	EFO_0006940
Disease	adverse effect, response to xenobiotic stimulus	LAMA1 ETS1 ST14	5.80e-04	59	81	3	EFO_0009658, GO_0009410
Disease	neuroimaging measurement	DNAJA3 ABO KIF26B FAT3 PLXND1 PLCH1 BBS9 KLHL20 PLCE1 TG	6.82e-04	1069	81	10	EFO_0004346
Disease	cancer biomarker measurement	ABO PPIP5K1	7.64e-04	15	81	2	EFO_0005127
Disease	YKL40 measurement	PPFIA4 ATP2B4	7.64e-04	15	81	2	EFO_0004869
Disease	interferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement	ABO F5	8.71e-04	16	81	2	EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
Disease	Synostotic Posterior Plagiocephaly	BBS9 FREM1	8.71e-04	16	81	2	C1833340
Disease	Craniosynostosis, Type 1	BBS9 FREM1	8.71e-04	16	81	2	C4551902
Disease	Acrocephaly	BBS9 FREM1	8.71e-04	16	81	2	C0030044
Disease	Trigonocephaly	BBS9 FREM1	8.71e-04	16	81	2	C0265535
Disease	Scaphycephaly	BBS9 FREM1	8.71e-04	16	81	2	C0265534
Disease	Synostotic Anterior Plagiocephaly	BBS9 FREM1	8.71e-04	16	81	2	C2931150
Disease	primary autosomal recessive microcephaly (is_implicated_in)	NCAPD3 NCAPH	8.71e-04	16	81	2	DOID:0070296 (is_implicated_in)
Disease	Metopic synostosis	BBS9 FREM1	8.71e-04	16	81	2	C1860819
Disease	Brachycephaly	BBS9 FREM1	9.85e-04	17	81	2	C0221356
Disease	hyperglycemia (implicated_via_orthology)	HK2 HK3	9.85e-04	17	81	2	DOID:4195 (implicated_via_orthology)
Disease	Ischemic stroke, venous thromboembolism, stroke, Abnormal thrombosis, deep vein thrombosis, pulmonary embolism	ABO F5	9.85e-04	17	81	2	EFO_0000712, EFO_0003827, EFO_0003907, EFO_0004286, HP_0001977, HP_0002140
Disease	myeloid white cell count	ABO GLG1 ETS1 CDT1 HDAC7 DENND2B ATP2B4 PLXNB1 PLCE1	1.07e-03	937	81	9	EFO_0007988
Disease	pentachlorophenol measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022071
Disease	parathion measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022070
Disease	potassium chromate measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022072
Disease	mercuric chloride measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022068
Disease	heptachlor epoxide measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022067
Disease	methoxychlor measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022069
Disease	4,6-dinitro-o-cresol measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022053
Disease	2,4,5-trichlorophenol measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022052
Disease	azinphos methyl measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022055
Disease	aldrin measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022054
Disease	dicofol measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022060
Disease	disulfoton measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022062
Disease	dieldrin measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022061
Disease	endrin measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022064
Disease	endosulfan measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022063
Disease	heptachlor measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022066
Disease	ethion measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022065
Disease	chlorpyrifos measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022057
Disease	cadmium chloride measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022056
Disease	diazinon measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022059
Disease	dibutyl phthalate measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0022058
Disease	environmental exposure measurement	EYS RPTOR F5	1.08e-03	73	81	3	EFO_0008360
Disease	cortical surface area measurement	NCAPD3 KIF26B CEP162 FAT3 ETS1 PLXND1 BBS9 FBN3 PLCE1 TRMT61A TG	1.10e-03	1345	81	11	EFO_0010736
Disease	DDT metabolite measurement	EYS RPTOR F5	1.12e-03	74	81	3	EFO_0007886
Disease	cup-to-disc ratio measurement	FRAS1 COL12A1 ABO GLG1 F5 PLCE1	1.20e-03	430	81	6	EFO_0006939
Disease	Craniosynostosis	BBS9 FREM1	1.37e-03	20	81	2	C0010278
Disease	venous thromboembolism, plasminogen activator inhibitor 1 measurement	ABO F5	1.51e-03	21	81	2	EFO_0004286, EFO_0004792
Disease	sudden cardiac arrest	LAMA1 PLCE1 DDX11	1.56e-03	83	81	3	EFO_0004278
Disease	venous thromboembolism, tissue plasminogen activator measurement	ABO F5	1.81e-03	23	81	2	EFO_0004286, EFO_0004791
Disease	partial thromboplastin time	ABO F5	1.98e-03	24	81	2	EFO_0004310
Disease	Varicose veins	ABO GLG1 ETS1 HDAC7	1.99e-03	193	81	4	HP_0002619
Disease	lymphocyte count	FRAS1 ABO ETS1 QPCT ELK4 PLXND1 PPIP5K2 NUBPL HDAC7 ATP2B4 PLCE1	2.15e-03	1464	81	11	EFO_0004587
Disease	inflammatory biomarker measurement	ABO F5	2.32e-03	26	81	2	EFO_0004872
Disease	migraine disorder, pulse pressure measurement	DNAJA3 PLCE1	2.32e-03	26	81	2	EFO_0005763, MONDO_0005277
Disease	hip circumference	ANKEF1 CCT6B POM121L2 PLXND1 ATP2B4	2.41e-03	338	81	5	EFO_0005093
Disease	blood strontium measurement	CEP162 RPTOR	2.50e-03	27	81	2	EFO_0021531
Disease	glucose metabolism disease (implicated_via_orthology)	HK2 HK3	2.69e-03	28	81	2	DOID:4194 (implicated_via_orthology)
Disease	blood cobalt measurement	EYS RPTOR F5	2.74e-03	101	81	3	EFO_0007577

Protein segments in the cluster

Peptide	Gene	Start	Entry
SLMPGSLERGFCMAV	ABO	41	P16442
PALSMEVACARMVGS	CDT1	471	Q9H211
MGMSRTVVLDEPTSG	ABCA13	3991	Q86UQ4
PAETTIAICSMIMGG	ACMSD	196	Q8TDX5
VSVACMRTGTVMIPG	ACSM5	131	Q6NUN0
VQDRMGCTPTMRAAE	ANKEF1	76	Q9NU02
GFMATPDMRTCVDVD	FBN3	1226	Q75N90
EASPRMSMCGEKREG	DENND2B	176	P78524
DMVRTVIEPMACDGL	ATP2B4	621	P23634
GATDSAVPCAMMLEL	QPCT	156	Q16769
GPGVTMSTCDVMLID	FRAS1	2741	Q86XX4
PVGSPGVVCMIEMTA	EYS	2246	Q5T1H1
AEMTCSGILPIDQMR	LSG1	451	Q9H089
TMEADRGMEGLISPT	NEK9	781	Q8TD19
GCQVVAPSDMMDGRV	ALAD	161	P13716
MCEVMPTINEGDRLG	PPFIA4	1	O75335
NEEGMMRCETATGPS	KIF26B	1456	Q2KJY2
STTEGCMGPVMSGNI	DSG4	981	Q86SJ6
NDTVGTMMTCGFEDP	HK2	656	P52789
VTPDNMCMGRTSRGK	ETS1	231	P14921
MSKEEVVAMIGDGPC	PLXNB1	1411	O43157
MRTDTSIACTMPEGA	PLXND1	1026	Q9Y4D7
PTIMTQGLCTRMVVG	OR5A1	136	Q8NGJ0
EDEALGVSCSMSPAM	FAM169B	106	Q8N8A8
MPVMNCSEGGEVVIT	FREM1	896	Q5H8C1
EGCAMNPELTMESLG	ONECUT2	16	O95948
PRKMVAIDCEMVGTG	ISG20L2	176	Q9H9L3
PMTELTVTERGFGTM	MPZL3	141	Q6UWV2
LLTGDGGRMVVTCME	MROH6	311	A6NGR9
SVTEMVISMRLPFCG	OR13J1	156	Q8NGT2
SDNLGRCVVMVGMPF	DDX11	786	Q96FC9
NDTVGTMMGCEPGVR	HK3	221	P52790
TRMVVCDLGNPMVSG	ITGA8	721	P53708
TMVMPGGCTTIPESD	BBS9	836	Q3SYG4
STPTVVMFGCDMESI	GRIN3A	321	Q8TCU5
GSSDMVCELLGVRGM	NT5DC4	296	Q86YG4
GSCAAISSMDMERPG	FZD10	16	Q9ULW2
AITPGRGRQMSCLME	GLG1	1081	Q92896
GSLGMMTSVLVCPDG	IDH1	286	O75874
MRRCTNIRPGETGMD	KLHL20	6	Q9Y2M5
TVMPILSSGMECLTR	COL12A1	1181	Q99715
LNMDPMTVGRIEGDC	ELK4	91	P28324
MARCGEGSAAPMVLL	BTBD8	1	Q5XKL5
FSDNLGRCVVMVGMP	DDX11L8	786	A8MPP1
GIITICKEPDMTTMG	FAT3	1621	Q8TDW7
VQDVGLVMPGAIMCS	DIP2C	701	Q9Y2E4
CLPEMTENEMTGTGV	CEP162	266	Q5TB80
PAMGSEEGMRAVSTG	MIDEAS	426	Q6PJG2
ARMVTMGIVRTSPCL	GARIN6	66	Q8NEG0
SCVMQEVGVIESPLM	IFNA8	121	P32881
RMFVMLPCGGVGVDT	HDAC7	611	Q8WUI4
GTGTEMPMIGDRVFV	FKBP4	41	Q02790
METINTGPFVMRSTC	DNAJA3	261	Q96EY1
CMSMGFLVEESEPVV	NUBPL	141	Q8TB37
PGMVSGAMETTRVTV	OTOG	1591	Q6ZRI0
TIIMSPRVCCLMVGG	OR4C6	131	Q8NH72
GVGMETCPPQMTARD	NUTM2B	666	A6NNL0
LLMRDTASGVMSCPQ	RTL9	591	Q8NET4
EFIIGMMGTLCAPAR	TCP11L1	181	Q9NUJ3
CMVPGAGAIEVAMAE	CCT6B	406	Q92526
DCRMPMGLSTGIISD	F5	1906	P12259
SMGSPCIEVDVLGMP	PLCE1	1886	Q9P212
RESPMVTVVGDGTML	LAMA1	2816	P25391
DNALCREGPMTGSVM	SOCS4	201	Q8WXH5
MECPVMETGSLFTSG	SGO2	1	Q562F6
TLSGMVCPIIVGAMT	SLC17A7	446	Q9P2U7
VPCSTEEMSRVLMGG	ESRP2	551	Q9H6T0
TPMDCDESGIIMTGP	POM121L2	896	Q96KW2
ELSPVLCMASRDVMG	PLAGL2	271	Q9UPG8
SDMLPTTRGAGMVVD	RPTOR	1116	Q8N122
SLSEMEIGMVVGGPE	SRF	101	P11831
GMVMGLRIRCDEGES	CLDND2	76	Q8NHS1
MISLGDGDIRTMCPL	NCAPH	406	Q15003
SGETVGSGERCVMAM	NCAPD3	531	P42695
RNLTAGMAMITCREP	CNOT1	1446	A5YKK6
MRSGEPACTMDQARG	ZBED3	1	Q96IU2
REMMEARGAGESCPT	TMEM247	6	A6NEH6
PRMMCVGFLSGGVDS	ST14	786	Q9Y5Y6
TMMLELRPGSVVCES	TRMT61A	96	Q96FX7
SPEKVERCMSVMQSG	PLCH1	11	Q4KWH8
ESVSTQMRRMGCPEL	TMEM209	356	Q96SK2
LRMMETEIQGDGCSG	ZNF233	66	A6NK53
PTTSGTMMELRCVIA	PPIP5K2	371	O43314
ETTPEGRMACQMGAD	TMEM169	141	Q96HH4
CAVLLGTLTPMATEM	UBR4	1511	Q5T4S7
MGSRPESMGCRKDTV	TG	1826	P01266
VPSPGMEEAGCSREM	UIMC1	651	Q96RL1
VPTTSGTMMELRCVI	PPIP5K1	381	Q6PFW1
QEPSCDSGILRMMSR	TMEM236	216	Q5W0B7
MPSERCLSIQEMLTG	KLHL32	1	Q96NJ5