Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	LIM	LHX2 PRICKLE2 ISL1 LHX8 LHX9	1.02e-05	69	78	5	PF00412
Domain	-	LHX2 PRICKLE2 ISL1 LHX8 LHX9	1.09e-05	70	78	5	2.10.110.10
Domain	Znf_LIM	LHX2 PRICKLE2 ISL1 LHX8 LHX9	1.17e-05	71	78	5	IPR001781
Domain	LIM_DOMAIN_1	LHX2 PRICKLE2 ISL1 LHX8 LHX9	1.17e-05	71	78	5	PS00478
Domain	LIM_DOMAIN_2	LHX2 PRICKLE2 ISL1 LHX8 LHX9	1.17e-05	71	78	5	PS50023
Domain	LIM	LHX2 PRICKLE2 ISL1 LHX8 LHX9	1.17e-05	71	78	5	SM00132
Domain	DM15	LARP1 LARP1B	1.72e-05	2	78	2	SM00684
Domain	NDUF_C2	NDUFC2-KCTD14 NDUFC2	1.72e-05	2	78	2	PF06374
Domain	KTI12	PSTK KTI12	1.72e-05	2	78	2	PF08433
Domain	KTI12/PSTK	PSTK KTI12	1.72e-05	2	78	2	IPR013641
Domain	NADH-UbQ_OxRdtase_b14.5b_su	NDUFC2-KCTD14 NDUFC2	1.72e-05	2	78	2	IPR009423
Domain	DM15	LARP1 LARP1B	1.72e-05	2	78	2	IPR006607
Domain	WxxW_domain	CILP CEMIP	2.55e-04	6	78	2	IPR025155
Domain	Mucin2_WxxW	CILP CEMIP	2.55e-04	6	78	2	PF13330
Domain	Anoct_dimer	ANO4 ANO1	3.57e-04	7	78	2	PF16178
Domain	Anoct_dimer	ANO4 ANO1	3.57e-04	7	78	2	IPR032394
Domain	La	LARP1 LARP1B	3.57e-04	7	78	2	PF05383
Domain	LA	LARP1 LARP1B	3.57e-04	7	78	2	SM00715
Domain	Lupus_La_RNA-bd	LARP1 LARP1B	3.57e-04	7	78	2	IPR006630
Domain	HTH_LA	LARP1 LARP1B	3.57e-04	7	78	2	PS50961
Domain	EGF	CNTNAP3B FCGBP TIE1 CNTNAP3 LAMB2 CUBN	4.49e-04	235	78	6	SM00181
Domain	EGF-like_dom	CNTNAP3B FCGBP TIE1 CNTNAP3 LAMB2 CUBN	6.09e-04	249	78	6	IPR000742
Domain	Anoctamin	ANO4 ANO1	7.58e-04	10	78	2	PF04547
Domain	Anoctamin	ANO4 ANO1	7.58e-04	10	78	2	IPR007632
Pathway	REACTOME_SIGNALING_BY_ERYTHROPOIETIN	PIK3CD PIK3R5 VAV1	4.54e-05	17	59	3	MM15584
Pubmed	Differential expression of LIM-homeodomain genes in the embryonic murine brain.	LHX2 ISL1 LHX8	2.24e-07	6	79	3	8817562
Pubmed	LIM homeobox transcription factors integrate signaling events that control three-dimensional limb patterning and growth.	LHX2 ISL1 LHX8 LHX9	3.01e-07	25	79	4	19304889
Pubmed	GATA4/FOG2 transcriptional complex regulates Lhx9 gene expression in murine heart development.	LHX2 ISL1 LHX9	3.92e-07	7	79	3	18577233
Pubmed	The m6A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expression.	LHX2 ISL1 LHX9	1.34e-06	10	79	3	30843071
Pubmed	Crossinhibitory activities of Ngn1 and Math1 allow specification of distinct dorsal interneurons.	LHX2 ISL1 LHX9	1.34e-06	10	79	3	11502254
Pubmed	BMP receptor-activated Smads confer diverse functions during the development of the dorsal spinal cord.	LHX2 ISL1 LHX9	1.84e-06	11	79	3	22609550
Pubmed	Combinatorial expression patterns of LIM-homeodomain and other regulatory genes parcellate developing thalamus.	LHX2 ISL1 LHX9	3.17e-06	13	79	3	11306624
Pubmed	LIM genes parcellate the embryonic amygdala and regulate its development.	LHX2 LHX8 LHX9	3.17e-06	13	79	3	15295034
Pubmed	Canonical BMP7 activity is required for the generation of discrete neuronal populations in the dorsal spinal cord.	LHX2 ISL1 LHX9	3.17e-06	13	79	3	22159578
Pubmed	Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor.	LHX2 ISL1 LHX8 LHX9	3.42e-06	45	79	4	23193182
Pubmed	Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus.	SIGLEC14 SIGLEC5	5.09e-06	2	79	2	24799499
Pubmed	The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.	CNTNAP3B CNTNAP3	5.09e-06	2	79	2	31150793
Pubmed	Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.	CNTNAP3B CNTNAP3	5.09e-06	2	79	2	26807827
Pubmed	Characterization of Lhx9, a novel LIM/homeobox gene expressed by the pioneer neurons in the mouse cerebral cortex.	LHX2 LHX9	5.09e-06	2	79	2	10330499
Pubmed	Immunomodulatory activity of extracellular Hsp70 mediated via paired receptors Siglec-5 and Siglec-14.	SIGLEC14 SIGLEC5	5.09e-06	2	79	2	26459514
Pubmed	NDUFC2 deficiency exacerbates endothelial mesenchymal transformation during ischemia-reperfusion via NLRP3.	NDUFC2-KCTD14 NDUFC2	5.09e-06	2	79	2	37506315
Pubmed	Proprioceptor pathway development is dependent on Math1.	LHX2 ISL1 LHX9	6.18e-06	16	79	3	11395003
Pubmed	BARHL2 transcription factor regulates the ipsilateral/contralateral subtype divergence in postmitotic dI1 neurons of the developing spinal cord.	LHX2 ISL1 LHX9	6.18e-06	16	79	3	22307612
Pubmed	Genetic ablation reveals that the roof plate is essential for dorsal interneuron specification.	LHX2 ISL1 LHX9	6.18e-06	16	79	3	10693795
Pubmed	Expression of LIM-homeodomain transcription factors in the developing and mature mouse retina.	LHX2 ISL1 LHX9	6.18e-06	16	79	3	24333658
Pubmed	Contribution of Hox genes to the diversity of the hindbrain sensory system.	LHX2 ISL1 LHX9	7.50e-06	17	79	3	14960494
Pubmed	Identification and subclassification of new Atoh1 derived cell populations during mouse spinal cord development.	LHX2 ISL1 LHX9	7.50e-06	17	79	3	19135992
Pubmed	Early thalamocortical tract guidance and topographic sorting of thalamic projections requires LIM-homeodomain gene Lhx2.	LHX2 ISL1 LHX9	1.06e-05	19	79	3	17493606
Pubmed	Dorsal and lateral fates in the mouse neural tube require the cell-autonomous activity of the open brain gene.	LHX2 ISL1 LHX9	1.25e-05	20	79	3	11071781
Pubmed	The bHLH factor Olig3 coordinates the specification of dorsal neurons in the spinal cord.	LHX2 ISL1 LHX9	1.25e-05	20	79	3	15769945
Pubmed	The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice.	LHX2 ISL1 LHX9	1.46e-05	21	79	3	20081193
Pubmed	Lbx1 specifies somatosensory association interneurons in the dorsal spinal cord.	LHX2 ISL1 LHX9	1.46e-05	21	79	3	12062038
Pubmed	Siglec-F-dependent negative regulation of allergen-induced eosinophilia depends critically on the experimental model.	SIGLEC14 SIGLEC5	1.53e-05	3	79	2	24698729
Pubmed	Allosteric Activation of Ubiquitin-Specific Proteases by β-Propeller Proteins UAF1 and WDR20.	WDR20 USP12	1.53e-05	3	79	2	27373336
Pubmed	Cloning and characterization of a novel mouse Siglec, mSiglec-F: differential evolution of the mouse and human (CD33) Siglec-3-related gene clusters.	SIGLEC14 SIGLEC5	1.53e-05	3	79	2	11579105
Pubmed	Discovery of Siglec-14, a novel sialic acid receptor undergoing concerted evolution with Siglec-5 in primates.	SIGLEC14 SIGLEC5	1.53e-05	3	79	2	17012248
Pubmed	Siglec-F is induced by granulocyte-macrophage colony-stimulating factor and enhances interleukin-4-induced expression of arginase-1 in mouse macrophages.	SIGLEC14 SIGLEC5	1.53e-05	3	79	2	31520477
Pubmed	Antiallergic effect of anti-Siglec-F through reduction of eosinophilic inflammation in murine allergic rhinitis.	SIGLEC14 SIGLEC5	1.53e-05	3	79	2	23710953
Pubmed	Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling.	SIGLEC14 SIGLEC5	1.53e-05	3	79	2	19783675
Pubmed	Mast Cell-Specific Expression of Human Siglec-8 in Conditional Knock-in Mice.	SIGLEC14 SIGLEC5	1.53e-05	3	79	2	30577572
Pubmed	A novel Siglec-F+ neutrophil subset in the mouse nasal mucosa exhibits an activated phenotype and is increased in an allergic rhinitis model.	SIGLEC14 SIGLEC5	1.53e-05	3	79	2	32247614
Pubmed	Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance.	CX3CR1 SOAT1	1.53e-05	3	79	2	25339759
Pubmed	LIM-homeodomain gene family in neural development.	LHX2 LHX8	1.53e-05	3	79	2	9078439
Pubmed	Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls.	SIGLEC14 SIGLEC5	1.53e-05	3	79	2	32134149
Pubmed	Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis.	SIGLEC14 SIGLEC5	1.53e-05	3	79	2	25497369
Pubmed	Siglec-F is a novel intestinal M cell marker.	SIGLEC14 SIGLEC5	1.53e-05	3	79	2	27524237
Pubmed	Differentiation and localization of interneurons in the developing spinal cord depends on DOT1L expression.	LHX2 ISL1 LHX9	1.68e-05	22	79	3	32471461
Pubmed	Cbln1 regulates axon growth and guidance in multiple neural regions.	LHX2 ISL1 LHX9	1.68e-05	22	79	3	36395107
Pubmed	Wnt signaling regulates ion channel expression to promote smooth muscle and cartilage formation in developing mouse trachea.	ANO4 ROR2 ANO1	1.93e-05	23	79	3	37873566
Pubmed	Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord.	LHX2 ISL1 LHX9	2.50e-05	25	79	3	15469980
Pubmed	β-Catenin signaling specifies progenitor cell identity in parallel with Shh signaling in the developing mammalian thalamus.	LHX2 ISL1 LHX9	2.50e-05	25	79	3	22745311
Pubmed	Characterization of a novel Lbx1 mouse loss of function strain.	LHX2 ISL1 LHX9	2.82e-05	26	79	3	34906895
Pubmed	Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus.	LHX2 ISL1 LHX8 LHX9	2.94e-05	77	79	4	21525287
Pubmed	Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity.	SIGLEC14 SIGLEC5	3.05e-05	4	79	2	17562860
Pubmed	Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils.	SIGLEC14 SIGLEC5	3.05e-05	4	79	2	17272508
Pubmed	Transcription factor Lhx2 is necessary and sufficient to suppress astrogliogenesis and promote neurogenesis in the developing hippocampus.	LHX2 LHX9	3.05e-05	4	79	2	21690374
Pubmed	Expression of the LIM-homeodomain gene Lmx1a (dreher) during development of the mouse nervous system.	LHX2 LHX9	3.05e-05	4	79	2	12351192
Pubmed	Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration.	SIGLEC14 SIGLEC5	3.05e-05	4	79	2	33289969
Pubmed	Ubiquitin-specific protease 12 interacting partners Uaf-1 and WDR20 are potential therapeutic targets in prostate cancer.	WDR20 USP12	3.05e-05	4	79	2	26462181
Pubmed	TEAD1, MYO7A and NDUFC2 are novel functional genes associated with glucose metabolism in BXD recombinant inbred population.	NDUFC2-KCTD14 NDUFC2	3.05e-05	4	79	2	38385898
Pubmed	IL-17 mediates protective immunity against nasal infection with Bordetella pertussis by mobilizing neutrophils, especially Siglec-F+ neutrophils.	SIGLEC14 SIGLEC5	3.05e-05	4	79	2	33976385
Pubmed	Alternative LIM homeodomain splice variants are dynamically regulated at key developmental steps in vertebrates.	LHX2 LHX9	3.05e-05	4	79	2	35247020
Pubmed	WDR20 prevents hepatocellular carcinoma senescence by orchestrating the simultaneous USP12/46-mediated deubiquitination of c-Myc.	WDR20 USP12	3.05e-05	4	79	2	39432777
Pubmed	Lhx9: a novel LIM-homeodomain gene expressed in the developing forebrain.	LHX2 LHX9	3.05e-05	4	79	2	9880598
Pubmed	Siglec-8 on human eosinophils and mast cells, and Siglec-F on murine eosinophils, are functionally related inhibitory receptors.	SIGLEC14 SIGLEC5	3.05e-05	4	79	2	19178537
Pubmed	The dystrophia myotonica WD repeat-containing protein DMWD and WDR20 differentially regulate USP12 deubiquitinase.	WDR20 USP12	3.05e-05	4	79	2	33844468
Pubmed	Induction of Siglec-FhiCD101hi eosinophils in the lungs following murine hookworm Nippostrongylus brasiliensis infection.	SIGLEC14 SIGLEC5	3.05e-05	4	79	2	37251384
Pubmed	CX3CL1 represses autophagy via CX3CR1/ CaMKIIδ/HDAC4/Rubicon axis and exacerbates chronic intermittent hypoxia induced Kupffer cell apoptosis.	RUBCN CX3CR1	3.05e-05	4	79	2	37640194
Pubmed	FLJ10261 gene, located within the CCND1-EMS1 locus on human chromosome 11q13, encodes the eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products.	ANO4 ANO1	3.05e-05	4	79	2	12739008
Pubmed	WDR20 regulates shuttling of the USP12 deubiquitinase complex between the plasma membrane, cytoplasm and nucleus.	WDR20 USP12	3.05e-05	4	79	2	30466959
Pubmed	Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons.	CNTNAP3B CNTNAP3 ISL1	3.95e-05	29	79	3	31491374
Pubmed	A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting.	SIGLEC14 SIGLEC5 ISL1	3.95e-05	29	79	3	33567267
Pubmed	Conversion of cerebral cortex into basal ganglia in Emx2(-/-) Pax6(Sey/Sey) double-mutant mice.	LHX2 ISL1 LHX8	4.38e-05	30	79	3	12118260
Pubmed	The zinc-finger transcription factor GLI3 is a regulator of precerebellar neuronal migration.	LHX2 ISL1 LHX9	4.84e-05	31	79	3	30470704
Pubmed	Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4.	PIK3CD PIK3R5	5.07e-05	5	79	2	20038597
Pubmed	Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs.	SIGLEC14 SIGLEC5	5.07e-05	5	79	2	20395633
Pubmed	Expression of major guidance receptors is differentially regulated in spinal commissural neurons transfated by mammalian Barh genes.	LHX2 LHX9	5.07e-05	5	79	2	20599893
Pubmed	Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13.	SIGLEC14 SIGLEC5	5.07e-05	5	79	2	21040544
Pubmed	WDR20 regulates activity of the USP12 x UAF1 deubiquitinating enzyme complex.	WDR20 USP12	5.07e-05	5	79	2	20147737
Pubmed	Differential expression of LIM-homeodomain factors in Cajal-Retzius cells of primates, rodents, and birds.	LHX2 LHX9	5.07e-05	5	79	2	19923199
Pubmed	Siglec-F-expressing neutrophils are essential for creating a profibrotic microenvironment in renal fibrosis.	SIGLEC14 SIGLEC5	5.07e-05	5	79	2	35482420
Pubmed	Developmental diversification of cortical inhibitory interneurons.	LHX2 NPAS3 ISL1 LHX8	5.67e-05	91	79	4	29513653
Pubmed	The ciliogenic transcription factor Rfx3 is required for the formation of the thalamocortical tract by regulating the patterning of prethalamus and ventral telencephalon.	LHX2 ISL1 LHX8	6.42e-05	34	79	3	25631876
Pubmed	The transcriptional control of trunk neural crest induction, survival, and delamination.	LHX2 ISL1 LHX9	6.42e-05	34	79	3	15691760
Pubmed	FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism.	LHX2 ISL1 LHX9	6.42e-05	34	79	3	18590716
Pubmed	ISLET1-Dependent β-Catenin/Hedgehog Signaling Is Required for Outgrowth of the Lower Jaw.	ISL1 LHX8 LHX9	7.01e-05	35	79	3	28069742
Pubmed	Motor and dorsal root ganglion axons serve as choice points for the ipsilateral turning of dI3 axons.	ISL1 LHX9	7.60e-05	6	79	2	21084609
Pubmed	A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins.	LHX2 ISL1	7.60e-05	6	79	2	9192866
Pubmed	Developmental specification of forebrain cholinergic neurons.	ISL1 LHX8	7.60e-05	6	79	2	27847324
Pubmed	Deubiquitinating enzyme Usp12 regulates the interaction between the androgen receptor and the Akt pathway.	WDR20 USP12	7.60e-05	6	79	2	25216524
Pubmed	Molecular analysis of human Siglec-8 orthologs relevant to mouse eosinophils: identification of mouse orthologs of Siglec-5 (mSiglec-F) and Siglec-10 (mSiglec-G).	SIGLEC14 SIGLEC5	7.60e-05	6	79	2	14559209
Pubmed	BMP type I receptor complexes have distinct activities mediating cell fate and axon guidance decisions.	LHX2 LHX9	7.60e-05	6	79	2	18272594
Pubmed	Interaction of Ras with p110γ is required for thymic β-selection in the mouse.	PIK3CD VAV1	7.60e-05	6	79	2	21930962
Pubmed	Galactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissue.	SIGLEC14 SIGLEC5	7.60e-05	6	79	2	23880769
Pubmed	In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.	CNTNAP3B CNTNAP3	7.60e-05	6	79	2	34143959
Pubmed	Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression.	PIK3CD CX3CR1	7.60e-05	6	79	2	30930171
Pubmed	Human cytomegalovirus UL138 interaction with USP1 activates STAT1 in infection.	WDR20 USP12	7.60e-05	6	79	2	37289831
Pubmed	Identification and characterization of TMEM16E and TMEM16F genes in silico.	ANO4 ANO1	7.60e-05	6	79	2	15067359
Pubmed	Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation.	PIK3CD VAV1	7.60e-05	6	79	2	18191593
Pubmed	Pilot genome-wide association search identifies potential loci for risk of erectile dysfunction in type 1 diabetes using the DCCT/EDIC study cohort.	PDK1 F13B	7.60e-05	6	79	2	22704111
Pubmed	PRC1 sustains the integrity of neural fate in the absence of PRC2 function.	LHX2 ISL1 LHX8	8.99e-05	38	79	3	34994686
Pubmed	Tissue-Specific Actions of Pax6 on Proliferation and Differentiation Balance in Developing Forebrain Are Foxg1 Dependent.	LHX2 ISL1 PRKG2	9.72e-05	39	79	3	30529950
Pubmed	The actin and tetraspanin networks organize receptor nanoclusters to regulate B cell receptor-mediated signaling.	PIK3CD VAV1	1.06e-04	7	79	2	23499492
Pubmed	Sialyltransferase ST3Gal-III regulates Siglec-F ligand formation and eosinophilic lung inflammation in mice.	SIGLEC14 SIGLEC5	1.06e-04	7	79	2	23677475
Pubmed	The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils.	SIGLEC14 SIGLEC5	1.06e-04	7	79	2	15048729
Interaction	PYGO1 interactions	LHX2 ISL1 LHX8 LHX9	3.96e-06	28	78	4	int:PYGO1
Interaction	LILRA5 interactions	CNTNAP3B MELTF CNTNAP3 LAMB2	6.88e-06	32	78	4	int:LILRA5
Interaction	CBLN4 interactions	CNTNAP3B MELTF CHST14 CNTNAP3 LAMB2 CEMIP	9.86e-06	127	78	6	int:CBLN4
Interaction	BTNL2 interactions	CNTNAP3B CHST14 ROR2 CNTNAP3 LAMB2 CEMIP	3.06e-05	155	78	6	int:BTNL2
Interaction	TRGV3 interactions	CNTNAP3B MELTF CNTNAP3 LAMB2	6.10e-05	55	78	4	int:TRGV3
Interaction	LDB2 interactions	LHX2 ISL1 LHX8 LHX9	6.55e-05	56	78	4	int:LDB2
Interaction	SSBP4 interactions	LHX2 ISL1 LHX8 LHX9	8.04e-05	59	78	4	int:SSBP4
GeneFamily	LIM class homeoboxes	LHX2 ISL1 LHX8 LHX9	3.20e-08	12	53	4	522
GeneFamily	La ribonucleoprotein domain containing\|RNA binding motif containing	LARP1 LARP1B	1.75e-04	7	53	2	625
GeneFamily	Anoctamins	ANO4 ANO1	3.74e-04	10	53	2	865
GeneFamily	CD molecules\|C2-set domain containing\|Sialic acid binding Ig like lectins	SIGLEC14 SIGLEC5	3.04e-03	28	53	2	745
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	TIE1 ROR2	6.12e-03	40	53	2	321
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1--L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ANO4 CNTNAP3B OR9G1 MYO3B CNTNAP3 ANO1 INPP5J	6.83e-08	200	79	7	4a426ef88376d8bb2b9dc50aa06e7b9fc50ecc9c
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ANO4 CNTNAP3B OR9G1 MYO3B CNTNAP3 ANO1 INPP5J	6.83e-08	200	79	7	fbeee1c16ac0a7fe28d90491c8b079f21ce80bdc
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ANO4 CNTNAP3B OR9G1 MYO3B CNTNAP3 ANO1 INPP5J	6.83e-08	200	79	7	c6eda342ea0cb37d71d89dbb8d11e819e0745172
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 CNTNAP3B CNTNAP3 ANO1 LRMDA INPP5J	9.06e-07	183	79	6	5a541a7f6c3514be8a13e988185dfe388c874f8b
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FCGBP PIK3CD LAIR1 PIK3R5 VAV1 CX3CR1	1.13e-06	190	79	6	773c55b9e28c2f77a5eb5f0adb0fa9862fb9611d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLFN12L PIK3CD LAIR1 PIK3R5 VAV1 CX3CR1	1.31e-06	195	79	6	2d485373bfd9bb4bb9236bf0b31d03e132c8018f
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	SCN2A NSG1 ISL1 LHX8 LRMDA XPR1	1.39e-06	197	79	6	4961f66606f08e399508fd6cabca588e7ab406a8
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTNAP3B FBXL7 TIE1 CNTNAP3 FAM124A TMEM178B	1.48e-06	199	79	6	3a4deea6e11a0555d27497b7c9983350797aac69
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	FCGBP GCNT3 ROR2 ANO1 NPAS3 TMEM178B	1.52e-06	200	79	6	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	18-Distal-Epithelial-Basal_cell\|Distal / Age, Tissue, Lineage and Cell class	MELTF DCDC1 MYO3B RHBDL1 CEMIP	9.16e-06	158	79	5	183f445967e09e871c93d8e94781ed9fec894169
ToppCell	PCW_05-06-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	TDRD15 LAIR1 SIGLEC14 VAV1 CX3CR1	1.20e-05	167	79	5	0d187e40a5b96b595761f7aea1a0835462d8270f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3CD LAIR1 CDC25C PIK3R5 VAV1	1.34e-05	171	79	5	55c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCell	facs-Kidney-nan-18m-Myeloid\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3CD LAIR1 PIK3R5 VAV1 CX3CR1	1.50e-05	175	79	5	2cb0d07a47bc645cfa690bb853e11d657af19ede
ToppCell	facs-Kidney-nan-18m-Myeloid-macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3CD LAIR1 PIK3R5 VAV1 CX3CR1	1.50e-05	175	79	5	cec941edec6849f2fb602c08fd1eed6d0345f934
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B MELTF CNTNAP3 ANO1 INPP5J	1.50e-05	175	79	5	11f49f00e000cbc137e3540a6d6805cde21d96e6
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FCGBP CEP95 LAMB2 INPP5J LHX9	1.50e-05	175	79	5	dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 ANO1 LRMDA INPP5J	1.50e-05	175	79	5	9d797888edb39fd12fd9cfc698a42b7bed19a5b5
ToppCell	facs-Kidney-nan-18m-Myeloid-macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3CD LAIR1 PIK3R5 VAV1 CX3CR1	1.50e-05	175	79	5	24d58e2f6d36124bde0f2c6f5357b9161bc5f476
ToppCell	Thalamus-Neuronal-Excitatory\|Thalamus / BrainAtlas - Mouse McCarroll V32	LHX2 PIK3CD SCN2A PRKG2 LHX9	1.54e-05	176	79	5	d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B MELTF CNTNAP3 ANO1 INPP5J	1.54e-05	176	79	5	95d5a4fdff1b9c715636684d22e06f8727ac0e7a
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B MELTF CNTNAP3 ANO1 INPP5J	1.59e-05	177	79	5	4f88ea4cfcfa8a9af5a14ab6f6be3b2aa015852e
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MELTF FCGBP TIE1 PIK3R5 CX3CR1	1.67e-05	179	79	5	06d412fc096d88de168969466ce422f0ab5553b2
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B MELTF CNTNAP3 ANO1 INPP5J	1.67e-05	179	79	5	3b0f8781232e1d42b6f8913bc989a14b3f978e79
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 CNTNAP3B CNTNAP3 ANO1 INPP5J	1.67e-05	179	79	5	d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LHX2 TIE1 PRICKLE2 LAMB2 FAM124A	1.77e-05	181	79	5	4df7972f88117108698efd06b124b232f8588981
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LHX2 TIE1 PRICKLE2 LAMB2 FAM124A	1.77e-05	181	79	5	cbb530566893281289026bfd93adf721decd4ca3
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B TIE1 CNTNAP3 NPAS3 LAMB2	1.86e-05	183	79	5	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	facs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l14\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FCGBP CILP ANO1 RHBDL1 CUBN	1.86e-05	183	79	5	6e5b39c0170d62eb7fdd411dcfff51ed176573d0
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B PIK3CD CNTNAP3 NPAS3 PRKG2	1.91e-05	184	79	5	23515c28e1f42aab29cef9e5b4a7f45bda7f5520
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 CNTNAP3B CNTNAP3 LRMDA INPP5J	1.91e-05	184	79	5	7d41784eac0935e77d6bc701f20c693adf998730
ToppCell	3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-cDC2\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIK3CD LAIR1 SIGLEC14 VAV1 CX3CR1	1.96e-05	185	79	5	e592c27f711d13bfc6546893acaab4c8600b0be1
ToppCell	PCW_05-06-Immune_Lymphocytic-Immune_Lymphocytic_B-im_lymphoid_progenitor_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PIK3CD LAIR1 PIK3R5 VAV1 CX3CR1	1.96e-05	185	79	5	5ec2c3ae5c477645241e8eaf19d222562e1f7ed6
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAIR1 LRMDA PIK3R5 VAV1 CX3CR1	2.01e-05	186	79	5	e41f14aee8cfbf76b8d0d4695a6170e2cd92aec8
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAIR1 LRMDA PIK3R5 VAV1 CX3CR1	2.01e-05	186	79	5	b3633cd4e360c5b45060c50b4f606d483e03a89a
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Micro\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAIR1 LRMDA PIK3R5 VAV1 CX3CR1	2.01e-05	186	79	5	9dd31dc9af1704f35c74de726a6c27fa21e9a014
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 CNTNAP3B MYO3B CNTNAP3 INPP5J	2.01e-05	186	79	5	6379609b7ace80683f5754b16aa77f11b43766ae
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAIR1 LRMDA PIK3R5 VAV1 CX3CR1	2.07e-05	187	79	5	23a42c172d5cc36cb8793c0bc2ce357c6c8e5d39
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 CNTNAP3B CNTNAP3 ANO1 INPP5J	2.07e-05	187	79	5	d413fb4b1531b297af5012a392b88128510c2de8
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B FBXL7 TIE1 CNTNAP3 TMEM178B	2.07e-05	187	79	5	e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FCGBP PIK3CD CDC25C PIK3R5 VAV1	2.07e-05	187	79	5	73931a5ea73799095daff100b5f18853c57c74dc
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	CNTNAP3B FBXL7 TIE1 CNTNAP3 NPAS3	2.07e-05	187	79	5	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANO4 ROR2 WDR20 RARS2 ARHGEF3	2.12e-05	188	79	5	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANO4 ROR2 WDR20 RARS2 ARHGEF3	2.12e-05	188	79	5	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANO4 ROR2 WDR20 RARS2 ARHGEF3	2.12e-05	188	79	5	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	Endothelial-endothelial_cell_of_lymph_vessel\|World / Lineage, Cell type, age group and donor	CNTNAP3B FBXL7 TIE1 CNTNAP3 NPAS3	2.12e-05	188	79	5	80910dcbb51990f2baed240f319456c0d3fa2065
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B FBXL7 TIE1 CNTNAP3 NPAS3	2.12e-05	188	79	5	c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3CD LAIR1 PIK3R5 VAV1 CX3CR1	2.12e-05	188	79	5	0d7296ad26e97ad91c6927a6cfe4e6e70a74c5a6
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTNAP3B SCN2A CNTNAP3 NPAS3 TMEM178B	2.12e-05	188	79	5	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 CNTNAP3B CNTNAP3 ANO1 INPP5J	2.12e-05	188	79	5	8de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B FBXL7 TIE1 CNTNAP3 NPAS3	2.12e-05	188	79	5	2db80767903703e7e0a1a37c598f7877a909ee94
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 CNTNAP3B CNTNAP3 INPP5J CEMIP	2.17e-05	189	79	5	99a13b1b669b0cd36e3096632351d9ade25d1173
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 CNTNAP3B CNTNAP3 ANO1 INPP5J	2.17e-05	189	79	5	78cf414b98bcb19deb934409acddaad1cd51b67f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B DCDC1 CUBN TMEM178B LRMDA	2.17e-05	189	79	5	28b502611829e4a24caff2562545c7db97686099
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 CNTNAP3B CNTNAP3 ANO1 INPP5J	2.23e-05	190	79	5	26843ec1d19ac85a50990705353b802745d33e4d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B FBXL7 TIE1 NPAS3 LRMDA	2.23e-05	190	79	5	656483751e4bf137e4e4bfb2a03a478a8f7fcb63
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FBXL7 SLC10A4 ROR2 ANO1 PRKG2	2.23e-05	190	79	5	3b8d1e66ae68c1eee64095e75195d76d97e24026
ToppCell	Fetal_29-31_weeks-Immune-T_lymphocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SLFN12L PDK1 PIK3CD PIK3R5 VAV1	2.23e-05	190	79	5	2a8de1cf27a9ebc3825cf9e7a489ecd064dfc7f9
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B FBXL7 TIE1 CNTNAP3 NPAS3	2.23e-05	190	79	5	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3CD LAIR1 PIK3R5 VAV1 CX3CR1	2.23e-05	190	79	5	7c402aa47f1bd7decacc366c1ed1a37e39b95c73
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 CNTNAP3B CNTNAP3 ANO1 INPP5J	2.23e-05	190	79	5	3f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel\|Adult / Lineage, Cell type, age group and donor	CNTNAP3B FBXL7 TIE1 CNTNAP3 NPAS3	2.23e-05	190	79	5	91bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B MYO3B CNTNAP3 ANO1 INPP5J	2.23e-05	190	79	5	39ab890104b4264c68a968f920f4ccd84f0bc681
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FBXL7 SLC10A4 ROR2 ANO1 PRKG2	2.23e-05	190	79	5	dc655e4782aab274f0c9b6e36a5ce315e3a1a4b9
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 CNTNAP3B MYO3B CNTNAP3 INPP5J	2.23e-05	190	79	5	0acf1d5da68db449d8c9e70519a236ce825f9d11
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 ANO1 INPP5J CEMIP	2.23e-05	190	79	5	e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_proliferating_myeloid_(8)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FCGBP LAIR1 PIK3R5 VAV1 CX3CR1	2.34e-05	192	79	5	7e7383093efaadceadd4d1f900c2d39cd690102e
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 CNTNAP3B SLC10A4 CNTNAP3 ANO1	2.34e-05	192	79	5	67d6230e32d446dcb12047fae2c3f1faa80dd720
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 CNTNAP3B CNTNAP3 ANO1 INPP5J	2.34e-05	192	79	5	0003d7ef9a8e521e70ac33c63aad843d9b6215c2
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 SLC10A4 NSG1 ANO1 NPAS3	2.40e-05	193	79	5	9f9eb241b0b82a6f12de6921c3acf6fed7cf65bb
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLFN12L PIK3CD LAIR1 PIK3R5 VAV1	2.46e-05	194	79	5	96f16bcd393a0d3f8df479b172b5360ae5a1e663
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B FBXL7 TIE1 NPAS3 LRMDA	2.46e-05	194	79	5	b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Neuronal-CFuPNs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	VRK1 ARID4A SCN2A NSG1 XPR1	2.52e-05	195	79	5	574354ef4bcefeb9856b65d19bb92e2cffe5dc7a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3CD LAIR1 PIK3R5 VAV1 CX3CR1	2.52e-05	195	79	5	ce8215d503cad3a9bc7d5d2be4adb57408015593
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3CD LAIR1 PIK3R5 VAV1 CX3CR1	2.52e-05	195	79	5	09df40ff9b493170861b3f6e57a942a834655b5c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3CD LAIR1 PIK3R5 VAV1 CX3CR1	2.59e-05	196	79	5	4370473693d2dd4a8c451a4c477eb79baa33ae12
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Neuronal-Subcortical\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	ARID4A SCN2A NSG1 ISL1 LHX9	2.59e-05	196	79	5	bf8fe28193348342987d361c8e8b9e1d6d542678
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CNTNAP3B TIE1 CNTNAP3 FAM124A CUBN	2.65e-05	197	79	5	ad4a3b5da2190be9495382a2952991e1de9f190d
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTNAP3B FBXL7 TIE1 FAM124A TMEM178B	2.65e-05	197	79	5	b0036cf3f7e6edf8e43f16cd2f0f0e80471d2576
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3CD LAIR1 PIK3R5 VAV1 CX3CR1	2.65e-05	197	79	5	57dafb3047745a44b2345b8036e159c3641d496e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLFN12L PIK3CD LAIR1 PIK3R5 VAV1	2.65e-05	197	79	5	61ef3f417767c3f5296a26399da63e3e4f58faf8
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FCGBP LAIR1 CDC25C PIK3R5 VAV1	2.72e-05	198	79	5	732a43061d75bc5e1cf23f5056b72cd10c926668
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3CD LAIR1 PIK3R5 VAV1 CX3CR1	2.72e-05	198	79	5	623f9d64c9e800d2d7f623392bf2f22b563f0249
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLFN12L PIK3CD PIK3R5 VAV1 CX3CR1	2.78e-05	199	79	5	7d69785717073491b5fb81bf24db0175f86cd0b0
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-MEPE-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B MYO3B CNTNAP3 ANO1 INPP5J	2.85e-05	200	79	5	d4161fcbbe47236aac4a077c0994887e765b0b47
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ANO4 CNTNAP3B CNTNAP3 ANO1 INPP5J	2.85e-05	200	79	5	1276bfa911fddada4235e12e3081baa53164574b
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-MEPE\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B MYO3B CNTNAP3 ANO1 INPP5J	2.85e-05	200	79	5	0d0c69758370d3c44ffe6640e332b6118fc5ce58
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLFN12L PIK3CD PIK3R5 VAV1 CX3CR1	2.85e-05	200	79	5	7d90fcb5dfc4c9d562c93b0f9293ed12b5f4f404
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-NK-ILC\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLFN12L PIK3CD PIK3R5 VAV1 CX3CR1	2.85e-05	200	79	5	d2422aaf807010194994db97142b9fd2e807312d
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-MEPE--L4-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B MYO3B CNTNAP3 ANO1 INPP5J	2.85e-05	200	79	5	c546fa80876640bd57a5252df611977009bef9e8
ToppCell	11.5-Distal-Immune\|Distal / Age, Tissue, Lineage and Cell class	LAIR1 SIGLEC14 PIK3R5 VAV1 CX3CR1	2.85e-05	200	79	5	c9ed06ae7a8f5a88578c8269d762d8739ae79c7f
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Cortical_neuron\|10w / Sample Type, Dataset, Time_group, and Cell type.	ARID4A SCN2A NSG1 LHX9 XPR1	2.85e-05	200	79	5	68c90376e2779434e4ad8dc6dd3b44baa700e2f4
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLFN12L PIK3CD PIK3R5 VAV1 CX3CR1	2.85e-05	200	79	5	1d2ee63010b7b8b38bea7d3b30eebfbcdd18b967
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	MELTF ARID4A MYO3B NSG1	6.82e-05	123	79	4	511b7c20a4a85e49980936d52af7dbca19bb848e
ToppCell	Globus_pallidus\|World / BrainAtlas - Mouse McCarroll V32	UNK ISL1 LHX8 XPR1	7.49e-05	126	79	4	44b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCell	facs-Lung-EPCAM-3m-Hematologic-leukocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L LHX2 GCNT3 VAV1	1.13e-04	140	79	4	731b46e4b815a45af1d0ce7ab4d0d0324ac8798f
ToppCell	facs-Lung-EPCAM-3m-Hematologic-Proliferating_Immune\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L LHX2 GCNT3 VAV1	1.13e-04	140	79	4	b30fc389583406ee6cb55112d0f7250d1b74c88a
ToppCell	facs-Lung-EPCAM-3m-Hematologic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L LHX2 GCNT3 VAV1	1.13e-04	140	79	4	35ecd887bb7827603ef673912ba820208a6368d2
ToppCell	facs-Pancreas-Exocrine-3m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3CD PIK3R5 VAV1 CX3CR1	1.39e-04	148	79	4	bbf4933582b50b3412c805de5ed137107c996236
ToppCell	facs-Pancreas-Exocrine-3m-Hematologic-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3CD PIK3R5 VAV1 CX3CR1	1.39e-04	148	79	4	6543860e3207a7de92a35bb6004be51287582f7a
ToppCell	facs-Pancreas-Exocrine-3m-Hematologic\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3CD PIK3R5 VAV1 CX3CR1	1.39e-04	148	79	4	79e376503a3f9504a1ec5af4a60a09cc80e19059
Disease	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 measurement	SIGLEC14 SIGLEC5 ARHGEF3	1.94e-06	10	76	3	EFO_0801544
Disease	facial asymmetry measurement	KLHDC1 NPAS3 CDC25C	1.54e-05	19	76	3	EFO_0009751
Disease	Pontocerebellar Hypoplasia Type 1	VRK1 RARS2	9.75e-05	6	76	2	C1843504
Disease	skin microbiome measurement	ANO4 LHX2 NPAS3	1.40e-04	39	76	3	EFO_0801228
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3	1.81e-04	8	76	2	DOID:0060308 (implicated_via_orthology)
Disease	sialic acid-binding Ig-like lectin 14 measurement	SIGLEC14 SIGLEC5	4.25e-04	12	76	2	EFO_0008284
Disease	Abruptio Placentae	TDRD15 FAM124A	4.25e-04	12	76	2	EFO_1001754
Disease	Congenital pontocerebellar hypoplasia	VRK1 RARS2	5.01e-04	13	76	2	C0266468
Disease	Pontoneocerebellar hypoplasia	VRK1 RARS2	7.67e-04	16	76	2	cv:C1261175
Disease	borna disease (biomarker_via_orthology)	PARG CX3CR1	9.75e-04	18	76	2	DOID:5154 (biomarker_via_orthology)
Disease	citrate measurement	CLTCL1 WDR20 POR	1.13e-03	79	76	3	EFO_0010114
Disease	susceptibility to scarlet fever measurement	PRSS58 SUCLA2 SOAT1	1.13e-03	79	76	3	EFO_0008409
Disease	complement factor H-related protein 2 measurement	LRMDA F13B	2.54e-03	29	76	2	EFO_0600055

Protein segments in the cluster

Peptide	Gene	Start	Entry
RRYNEDYLKYGFIKC	FAM200B	61	P0CF97
RIEVYGCAYKSEVVY	CNTNAP3	171	Q9BZ76
GESECRYYKERLLYL	ARHGEF3	306	Q9NR81
KYLYGFEEYCRSANI	ARID4A	391	P29374
LIYAFAGEKFRRYLY	CX3CR1	291	P49238
YFRDGKCRIDYILVY	ANO4	111	Q32M45
VYKKGQDYRFACYDR	CEMIP	376	Q8WUJ3
IYYRGAKAAIVCYDL	RAB24	76	Q969Q5
CYLLAAVAYDRYVAI	OR9G1	111	Q8NH87
DGYENARRLCDLYYI	PDK1	231	Q15118
GVFIRYKYSRVADYI	SLC10A4	251	Q96EP9
FDRYVAICYPLRYTI	OR52Z1P	106	P0C646
RYFYDLYGRKIEDIS	DCDC1	336	M0R2J8
LECLFRYYSYGLEKK	LARP1	951	Q6PKG0
KDEEDYKRYRCFVLY	LRMDA	96	Q9H2I8
LLYYGCRRSDEDYLY	POR	561	P16435
LNYIKGFRYELYCLA	KTI12	81	Q96EK9
RALRYYYDGDMICKV	GABPA	376	Q06546
CREVILGYDYLENAY	KIAA2026	456	Q5HYC2
VREGNAGLYRCIYYK	LAIR1	91	Q6GTX8
HYGKEIVRFTVYCRY	FAM124A	166	Q86V42
VEYRCNEYYLLRGSK	F13B	421	P05160
GSIYCKEDYYRRFSV	LHX9	116	Q9NQ69
GDVYKLLLRYYNEEC	PARG	926	Q86W56
GYYLVKREDYLYAVR	NDUFC2	71	O95298
IREKYYYALYELVVR	LAMB2	266	P55268
KDGSIYCKEDYYRRF	LHX2	96	P50458
DIFCKLDYFRRYGTR	LHX8	121	Q68G74
CVVFLVVYKVYKYDR	NSG1	96	P42857
YGLYFRDGRRKVDYI	ANO1	51	Q5XXA6
GYEVQICRYKDYREP	ANO1	856	Q5XXA6
GALDYYKRYRVRSYE	RBM4B	216	Q9BQ04
LGYRCRFNEDFKYVL	P2RY2	21	P41231
CLEVEYYDKGDYIIR	PRKG2	301	Q13237
LIEKFYVIDCRYPYE	CDC25C	321	P30307
DLIYFYQDGKIYCGR	PRICKLE2	171	Q7Z3G6
TRQRCLYDYVKLYDG	CUBN	3211	O60494
VGIRYVAKYCSKLRY	FBXL7	366	Q9UJT9
DFGLRVAYDLVYYVR	FCGBP	1361	Q9Y6R7
LQCLEEYLRYKAIYG	GCNT3	421	O95395
VRVEIRRCLYYFYKF	IFNK	186	Q9P0W0
ARKYYDDYRVQLCAK	CEP95	666	Q96GE4
DALYVRGLCLYYEDC	DNAJC7	211	Q99615
VYKDRLIYFGGYGCR	KLHDC1	131	Q8N7A1
DYIKRLRYCEYLGKY	RUBCN	731	Q92622
RIEVYGCAYKSEVVY	CNTNAP3B	171	Q96NU0
KENYRYGLECLFRFY	LARP1B	766	Q659C4
EYIRVYKRLGVYFDE	RARS2	251	Q5T160
YVYYIFERLCAPLFR	SOAT1	336	P35610
RKGEIERCTYIKYHY	TMEM178B	126	H3BS89
VLRADVGIYAKIFYY	PRSS58	216	Q8IYP2
ERYYGYRGAFRCLVE	MELTF	551	P08582
CLVLVDYGFSFYIRY	TDRD15	1811	B5MCY1
YFFRVERGRDVKYSY	SIGLEC5	116	O15389
RKIYRYDGIYCESTY	NPAS3	31	Q8IXF0
RELYFYIYKGVRKAA	WDR20	71	Q8TBZ3
LFREVYAADYYKLLG	ROR2	636	Q01974
RDGKTYCKRDYIRLY	ISL1	61	P61371
YKRFVRYVAYEILPC	RHBDL1	166	O75783
LVCERKYPRREYYFA	SUCLA2	156	Q9P2R7
YERLDAIRFYYGDRV	CILP	71	O75339
VELCYRALQFYLDYK	CLTCL1	1401	P53675
ILVSDRYRFLYCYVP	CHST14	141	Q8NCH0
YRVGFRHCKDYVAYV	INPP5J	776	Q15735
KAYYYCAIIEDVILR	XPR1	556	Q9UBH6
YDKGRLCGYVYALRV	SLFN12L	311	Q6IEE8
YYCRFAARPVLLQVY	PIK3R5	661	Q8WYR1
ACKNRGYLYIAIEYA	TIE1	906	P35590
YEVYQLARKYSLGFC	PSTK	161	Q8IV42
IKYKERFLVYGRYCS	VAV1	271	P15498
GECVLKLISLRYYYF	SCN2A	1576	Q99250
ALYFCRPFREKVLAY	USP12	56	O75317
EKFERFRGYCERAYT	PIK3CD	951	O00329
LEYYDFYEVACKDRL	UBE2Z	276	Q9H832
DQVYLVDYGLAYRYC	VRK1	191	Q99986
GYYLVKREDYLYAVR	NDUFC2-KCTD14	71	E9PQ53
TERRYHLRYYKTGIC	UNK	116	Q9C0B0
RFFYGCREYFHKLLI	WDR7	331	Q9Y4E6
YFFRVERGRDVKYSY	SIGLEC14	116	Q08ET2
RILFEEFVKRYYYLA	MYO3B	996	Q8WXR4
YYSRKVIRAYLECAL	NAT8L	151	Q8N9F0