Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessvesicle transport along actin filament

MYO5A MYO5B ACTN4

2.71e-069673GO:0030050
GeneOntologyBiologicalProcessactin filament-based transport

MYO5A MYO5B ACTN4

5.31e-0611673GO:0099515
GeneOntologyBiologicalProcessestablishment of vesicle localization

SEC16B RASGRP1 MYO5A SEPTIN5 MYO5B ACTN4 ATP9A

8.11e-06224677GO:0051650
GeneOntologyBiologicalProcessvesicle localization

SEC16B RASGRP1 MYO5A SEPTIN5 MYO5B ACTN4 ATP9A

1.53e-05247677GO:0051648
GeneOntologyBiologicalProcessregulation of vesicle-mediated transport

GH1 MYO5A SEPTIN5 MYO5B SEPTIN4 LRP2 DYNC1LI1 ACTN4 ATP9A CASK

5.49e-056676710GO:0060627
GeneOntologyBiologicalProcessvesicle cytoskeletal trafficking

RASGRP1 MYO5A MYO5B ACTN4

6.68e-0567674GO:0099518
GeneOntologyBiologicalProcessnegative regulation of G2/M transition of mitotic cell cycle

BLM CDC14B USP47 RAD21

1.04e-0475674GO:0010972
GeneOntologyBiologicalProcessregulation of exocytosis

MYO5A SEPTIN5 MYO5B SEPTIN4 ATP9A CASK

1.09e-04233676GO:0017157
GeneOntologyBiologicalProcessnegative regulation of cell cycle G2/M phase transition

BLM CDC14B USP47 RAD21

1.15e-0477674GO:1902750
GeneOntologyCellularComponentpostsynaptic actin cytoskeleton

MYO5A MYO5B PPP1R9A ACTN4

3.39e-0719664GO:0098871
GeneOntologyCellularComponentpostsynaptic cytoskeleton

MYO5A MYO5B PPP1R9A ACTN4

1.29e-0626664GO:0099571
GeneOntologyCellularComponentseptin complex

SEPTIN8 SEPTIN5 SEPTIN4

1.07e-0514663GO:0031105
GeneOntologyCellularComponentseptin ring

SEPTIN8 SEPTIN5 SEPTIN4

1.07e-0514663GO:0005940
GeneOntologyCellularComponentseptin cytoskeleton

SEPTIN8 SEPTIN5 SEPTIN4

1.63e-0516663GO:0032156
GeneOntologyCellularComponentcell cortex

SEPTIN8 SHROOM3 SEPTIN5 MYO5B SEPTIN4 PPP1R9A ACTN4 BFSP1

2.14e-05371668GO:0005938
GeneOntologyCellularComponentdendrite

AKAP9 MYO5A MYO5B SACS SEPTIN4 PPP1R9A LRP2 GNAZ ASAP1 CASK ITPR3

7.11e-058586611GO:0030425
GeneOntologyCellularComponentdendritic tree

AKAP9 MYO5A MYO5B SACS SEPTIN4 PPP1R9A LRP2 GNAZ ASAP1 CASK ITPR3

7.26e-058606611GO:0097447
GeneOntologyCellularComponentactin cytoskeleton

SHROOM3 MYO5A SEPTIN5 MYO5B PPP1R9A ACTN4 ASAP1 CASK

4.46e-04576668GO:0015629
GeneOntologyCellularComponentaxon

SEPTIN8 KCNA6 RNF6 MYO5A SEPTIN5 SACS SEPTIN4 PPP1R9A LRP2 ROBO2

4.55e-048916610GO:0030424
GeneOntologyCellularComponentsomatodendritic compartment

AKAP9 MYO5A MYO5B SACS SEPTIN4 PPP1R9A LRP2 GNAZ ASAP1 CASK ITPR3

1.50e-0312286611GO:0036477
MousePhenositus inversus with levocardia

TMEM67 GAS8 DNAH5

2.22e-067573MP:0011253
MousePhenoimpaired contextual conditioning behavior

MYT1L CDC14C KMT2D CDC14B GNPAT

5.54e-05101575MP:0009454
MousePhenoabnormal digestive organ placement

TMEM67 GAS8 ACTN4 DNAH5

8.35e-0557574MP:0003283
MousePhenoabnormal axial skeleton morphology

CDC14C ADK TMEM67 SHROOM3 KMT2D AKAP9 SACS MTHFR LRP2 DYNC1LI1 CHD1 ACTN4 DNAH5 CDC14B ASAP1 CASK

1.65e-0414585716MP:0002114
MousePhenoabnormal cerebellum morphology

TMEM67 MYO5A SACS MTHFR LRP2 ROBO2 DNAH5 GNPAT

1.68e-04389578MP:0000849
MousePhenoabnormal cerebellar cortex morphology

TMEM67 MYO5A SACS MTHFR LRP2 ROBO2 GNPAT

2.06e-04300577MP:0004097
MousePhenoabnormal postnatal growth

BLM ADK TMEM67 MYO5A MTHFR ACTN4 DNAH5 ASAP1 MYBL1 GNPAT CASK ITPR3

2.42e-049075712MP:0001731
MousePhenoexcessive vocalization

MYT1L ITPR3

2.42e-046572MP:0013140
MousePhenowrinkled skin

MYO5B MYBL1 CASK

2.66e-0431573MP:0001211
MousePhenoright-sided stomach

TMEM67 GAS8 DNAH5

2.66e-0431573MP:0010808
MousePhenoabnormal metencephalon morphology

TMEM67 MYO5A SACS MTHFR LRP2 ROBO2 DNAH5 GNPAT

2.82e-04420578MP:0000847
MousePhenoabsent anterior visceral endoderm

CHD1 GDF3

3.39e-047572MP:0012159
MousePhenoabnormal learning/memory/conditioning

MYT1L CDC14C ADK TMEM67 KMT2D KCNA6 MYO5A TYW1B SEPTIN5 DYNC1LI1 ATP9A CDC14B GNPAT ITPR3

3.48e-0412395714MP:0002063
MousePhenoabnormal cognition

MYT1L CDC14C ADK TMEM67 KMT2D KCNA6 MYO5A TYW1B SEPTIN5 DYNC1LI1 ATP9A CDC14B GNPAT ITPR3

3.69e-0412465714MP:0014114
MousePhenoabnormal dendrite morphology

MYT1L MYO5A SACS DYNC1LI1 ROBO2 ATP9A

3.93e-04237576MP:0008143
MousePhenoabnormal neurite morphology

MYT1L SEPTIN8 MYO5A SACS DYNC1LI1 ROBO2 ATP9A GNPAT

3.98e-04442578MP:0008415
MousePhenoabnormal stomach position or orientation

TMEM67 GAS8 DNAH5

4.17e-0436573MP:0010807
DomainSeptin

SEPTIN8 SEPTIN5 SEPTIN4

1.02e-0513633PF00735
DomainG_SEPTIN_dom

SEPTIN8 SEPTIN5 SEPTIN4

1.02e-0513633IPR030379
DomainG_SEPTIN

SEPTIN8 SEPTIN5 SEPTIN4

1.02e-0513633PS51719
DomainSeptin

SEPTIN8 SEPTIN5 SEPTIN4

1.30e-0514633IPR016491
DomainMyosin_S1_N

MYO5A MYO5B

1.11e-045632IPR008989
DomainP-loop_NTPase

BLM SEPTIN8 MYO5A SEPTIN5 MYO5B SEPTIN4 DYNC1LI1 CHD1 GNAZ DNAH5 CASK

1.12e-048486311IPR027417
DomainDIL

MYO5A MYO5B

1.67e-046632PF01843
DomainDilute_dom

MYO5A MYO5B

1.67e-046632IPR002710
DomainDILUTE

MYO5A MYO5B

1.67e-046632PS51126
DomainDIL

MYO5A MYO5B

1.67e-046632SM01132
DomainK_chnl_volt-dep_Kv1

KCNA6 KCNA10

3.09e-048632IPR003972
Domain-

BLM SEPTIN8 SEPTIN5 SEPTIN4 DYNC1LI1 CHD1 GNAZ DNAH5 CASK

8.45e-047466393.40.50.300
DomainLdl_recept_b

NID2 LRP2

9.93e-0414632PF00058
DomainLDLRB

NID2 LRP2

9.93e-0414632PS51120
DomainLY

NID2 LRP2

1.14e-0315632SM00135
DomainLDLR_classB_rpt

NID2 LRP2

1.14e-0315632IPR000033
DomainPDZ

SHROOM3 LNX2 PPP1R9A CASK

1.31e-03141634PF00595
DomainPDZ

SHROOM3 LNX2 PPP1R9A CASK

1.57e-03148634SM00228
Domain-

SHROOM3 LNX2 PPP1R9A CASK

1.65e-031506342.30.42.10
DomainPDZ

SHROOM3 LNX2 PPP1R9A CASK

1.69e-03151634PS50106
DomainPDZ

SHROOM3 LNX2 PPP1R9A CASK

1.73e-03152634IPR001478
DomaincEGF

NID2 LRP2

3.45e-0326632IPR026823
DomaincEGF

NID2 LRP2

3.45e-0326632PF12662
DomainK_chnl_volt-dep_Kv

KCNA6 KCNA10

3.72e-0327632IPR003968
DomainVG_K_chnl

KCNA6 KCNA10

5.53e-0333632IPR028325
DomainDNA/RNA_helicase_DEAH_CS

BLM CHD1

6.20e-0335632IPR002464
DomainIon_trans_dom

KCNA6 KCNA10 ITPR3

6.74e-03114633IPR005821
DomainIon_trans

KCNA6 KCNA10 ITPR3

6.74e-03114633PF00520
DomainDEAH_ATP_HELICASE

BLM CHD1

7.28e-0338632PS00690
DomainMyosin_head_motor_dom

MYO5A MYO5B

7.28e-0338632IPR001609
DomainMYOSIN_MOTOR

MYO5A MYO5B

7.28e-0338632PS51456
DomainMyosin_head

MYO5A MYO5B

7.28e-0338632PF00063
Pubmed

The novel human platelet septin SEPT8 is an interaction partner of SEPT4.

SEPTIN8 SEPTIN5 SEPTIN4

6.83e-09367315116257
Pubmed

Human septin-septin interactions as a prerequisite for targeting septin complexes in the cytosol.

SEPTIN8 SEPTIN5 SEPTIN4

6.83e-09367315214843
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

MYO5A SEPTIN5 SACS PPP1R9A DYNC1LI1 ACTN4 GNAZ ASAP1

7.10e-0828167828706196
Pubmed

Superfluous role of mammalian septins 3 and 5 in neuronal development and synaptic transmission.

SEPTIN8 SEPTIN5 SEPTIN4

5.69e-07967318809578
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

BLM KMT2D AKAP9 MYO5A MYO5B PPP1R9A PIK3R3 ACTN4 CDC14B ASAP1 CASK ITPR3

6.93e-071049671227880917
Pubmed

Overexpression of CDC14B causes mitotic arrest and inhibits zygotic genome activation in mouse preimplantation embryos.

CDC14C CDC14B

3.66e-06267219923902
Pubmed

The Cdc14B phosphatase displays oncogenic activity mediated by the Ras-Mek signaling pathway.

CDC14C CDC14B

3.66e-06267221502810
Pubmed

Isolation of new splice isoforms, characterization and expression analysis of the human septin SEPT8 (KIAA0202).

SEPTIN8 SEPTIN5

3.66e-06267212909369
Pubmed

Birth and rapid subcellular adaptation of a hominoid-specific CDC14 protein.

CDC14C CDC14B

3.66e-06267218547142
Pubmed

Human septin-septin interaction: CDCrel-1 partners with KIAA0202.

SEPTIN8 SEPTIN5

3.66e-06267212023038
Pubmed

Synthetic embryonic lethality upon deletion of the ER cochaperone p58(IPK) and the ER stress sensor ATF6α.

ATF6 DNAJC3

3.66e-06267224275136
Pubmed

Localization of septin proteins in the mouse cochlea.

SEPTIN8 SEPTIN5 SEPTIN4

3.76e-061667322575789
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ATF6 SHROOM3 MYO5A SEPTIN5 KIAA0232 PPP1R9A PIK3R3 HECTD4 GNAZ DNAJC3 CDC14B NSMAF CASK

4.52e-061489671328611215
Pubmed

Early-onset aging and defective DNA damage response in Cdc14b-deficient mice.

CDC14C CDC14B

1.10e-05367221262768
Pubmed

Septin expression in proliferative retinal membranes.

SEPTIN8 SEPTIN5

1.10e-05367217625225
Pubmed

Human Rab small GTPase- and class V myosin-mediated membrane tethering in a chemically defined reconstitution system.

MYO5A MYO5B

1.10e-05367228939769
Pubmed

Palmitoylation is required for Sept8-204 and Sept5 to form vesicle-like structure and colocalize with synaptophysin.

SEPTIN8 SEPTIN5

1.10e-05367238308620
Pubmed

The temporal and spatial expression pattern of myosin Va, Vb and VI in the mouse ovary.

MYO5A MYO5B

1.10e-05367216713372
Pubmed

Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription.

CDC14C CDC14B

1.10e-05367222355704
Pubmed

CDC14B acts through FZR1 (CDH1) to prevent meiotic maturation of mouse oocytes.

CDC14C CDC14B

1.10e-05367219129509
Pubmed

Role for myosin-V motor proteins in the selective delivery of Kv channel isoforms to the membrane surface of cardiac myocytes.

MYO5A MYO5B

1.10e-05367224508725
Pubmed

Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair.

CDC14C CDC14B

1.10e-05367226283732
Pubmed

Structural insights into the globular tails of the human type v myosins Myo5a, Myo5b, And Myo5c.

MYO5A MYO5B

1.10e-05367224339992
Pubmed

Human endothelial cell septins: SEPT11 is an interaction partner of SEPT5.

SEPTIN8 SEPTIN5

1.10e-05367216767699
Pubmed

Structural insights into functional overlapping and differentiation among myosin V motors.

MYO5A MYO5B

1.10e-05367224097982
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SEPTIN8 MYO5A SEPTIN5 MYO5B SACS SEPTIN4 PPP1R9A ACTN4 GNAZ ATP9A ASAP1 CASK

1.66e-051431671237142655
Pubmed

CDC14A phosphatase is essential for hearing and male fertility in mouse and human.

CDC14C CDC14B

2.19e-05467229293958
Pubmed

Structural basis of myosin V Rab GTPase-dependent cargo recognition.

MYO5A MYO5B

2.19e-05467224248336
Pubmed

Alternative splicing in class V myosins determines association with Rab10.

MYO5A MYO5B

2.19e-05467219008234
Pubmed

SEPT5_v2 is a parkin-binding protein.

SEPTIN5 SEPTIN4

2.19e-05467214559152
Pubmed

Sept12 is a component of the mammalian sperm tail annulus.

SEPTIN8 SEPTIN4

2.19e-05467217685441
Pubmed

Mis12 controls cyclin B1 stabilization via Cdc14B-mediated APC/CCdh1 regulation during meiotic G2/M transition in mouse oocytes.

CDC14C CDC14B

2.19e-05467232341029
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

BLM ATF6 SHROOM3 AKAP9 MYO5A SACS PIK3R3 CHD1 DNAJC3 CASK RAD21 ITPR3

2.42e-051487671233957083
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

SEPTIN8 MYO5A SEPTIN5 MYO5B SEPTIN4 CHD1 GNAZ ASAP1

2.55e-0562167822794259
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

MYT1L ATF6 MYO5A SACS USP32 HECTD4 LRP2 ACTN4 BFSP1 USP47 CASK

3.23e-051285671135914814
Pubmed

Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study.

CACNA2D4 SACS LRP2

3.26e-053267325189868
Pubmed

Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity.

SEPTIN5 SEPTIN4

3.64e-05567217296554
Pubmed

CART: an Hrs/actinin-4/BERP/myosin V protein complex required for efficient receptor recycling.

MYO5A ACTN4

3.64e-05567215772161
Pubmed

Loss-of-Function GAS8 Mutations Cause Primary Ciliary Dyskinesia and Disrupt the Nexin-Dynein Regulatory Complex.

GAS8 DNAH5

3.64e-05567226387594
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

MYO5A USP32 HECTD4 LRP2 ACTN4 USP47 ITPR3

3.94e-0548167728190767
Pubmed

Hepatocyte DACH1 Is Increased in Obesity via Nuclear Exclusion of HDAC4 and Promotes Hepatic Insulin Resistance.

ATF6 DNAJC3

5.46e-05667227239042
Pubmed

Physical mapping of potassium channel gene clusters on mouse chromosomes three and six.

KCNA6 KCNA10

5.46e-0566729286706
Pubmed

Trip6 promotes dendritic morphogenesis through dephosphorylated GRIP1-dependent myosin VI and F-actin organization.

MYO5A MYO5B

5.46e-05667225673849
Pubmed

Pore size matters for potassium channel conductance.

KCNA6 KCNA10

7.63e-05767227619418
Pubmed

Differential localization of septins in the mouse brain.

SEPTIN5 SEPTIN4

7.63e-05767211064363
Pubmed

Congenital Diaphragmatic Hernia Overview

KMT2D LRP2 RAD21

9.78e-054667320301533
Pubmed

International Lung Cancer Consortium: coordinated association study of 10 potential lung cancer susceptibility variants.

AKAP9 MTHFR

1.30e-04967220106900
Pubmed

LDL receptor-related protein as a component of the midkine receptor.

NID2 LRP2

1.30e-04967210772929
Pubmed

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.

KMT2D MYO5A MYO5B HECTD4 ACTN4

1.60e-0426467532814769
Pubmed

DCHS1, Lix1L, and the Septin Cytoskeleton: Molecular and Developmental Etiology of Mitral Valve Prolapse.

SEPTIN8 SEPTIN5

1.63e-041067235200715
Pubmed

Association of genetic polymorphisms with hepatotoxicity in patients with childhood acute lymphoblastic leukemia or lymphoma.

RASGRP1 MTHFR

1.63e-041067220670164
Pubmed

The septin CDCrel-1 is dispensable for normal development and neurotransmitter release.

SEPTIN5 SEPTIN4

1.63e-041067211739749
Pubmed

Identification and validation of novel spinophilin-associated proteins in rodent striatum using an enhanced ex vivo shotgun proteomics approach.

MYO5A PPP1R9A

1.63e-041067220124353
Pubmed

rec-YnH enables simultaneous many-by-many detection of direct protein-protein and protein-RNA interactions.

AKAP9 MYO5A DYNC1LI1 CASK

1.67e-0414267430217970
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

SEPTIN8 DYNC1LI1 ACTN4 GNAZ ATP9A CASK

1.82e-0443067632581705
Pubmed

Interleukin 10 polymorphisms differentially influence the risk of gastric cancer in East Asians and Caucasians.

MTHFR CHD1

1.99e-041167220363151
Pubmed

High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1.

SEPTIN4 CASK

1.99e-041167219523119
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

MYT1L SEPTIN8 TYW1B LRP2 ACTN4 AKR1C4 PCDH18 SPTY2D1 ASAP1

2.27e-04108467911544199
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

SEPTIN8 SHROOM3 KIAA0232 LRP2 DYNC1LI1 ACTN4 ASAP1 USP47

2.30e-0485367828718761
Pubmed

A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary gland.

MYT1L LRP2

2.38e-04126728631881
Pubmed

Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1.

PIK3C2G AKR1C4

2.38e-041267228893949
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

BLM MYO5A CHD1 ACTN4 USP47 RAD21 ITPR3

2.61e-0465367722586326
Pubmed

A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa.

NALF1 LRP2

2.81e-041367221079607
Pubmed

140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry.

SEPTIN8 SEPTIN5 SEPTIN4 DYNC1LI1

2.83e-0416367416512683
Pubmed

Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity.

SEPTIN5 SEPTIN4 ACTN4 GNAZ

3.04e-0416667427160897
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

SACS LRP2

3.28e-041467215082773
Pubmed

Targeting TRIM3 deletion-induced tumor-associated lymphangiogenesis prohibits lymphatic metastasis in esophageal squamous cell carcinoma.

MYO5A ACTN4

3.28e-041467230542119
Pubmed

Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.

MYO5A MYO5B

3.28e-04146728022818
Pubmed

Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS-Hook-FHIP complexes.

MYO5A MYO5B ATP9A

3.71e-047267334882091
Pubmed

A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.

LNX2 AKAP9 ACTN4 DNAJC3 CASK ITPR3

4.20e-0450367636217030
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

ATF6 TYW1B USP32 LRP2 ATP9A ITPR3

4.25e-0450467634432599
Pubmed

Partial transcriptome of the developing pituitary gland.

ATP9A CASK

4.31e-041667211161784
Pubmed

Unpackaging the genetics of mammalian fertility: strategies to identify the "reproductive genome".

AKAP9 MYBL1

4.31e-041667229878059
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

AKAP9 SACS USP47

4.34e-047667327542412
Pubmed

PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.

BLM KMT2D

5.48e-041867217500065
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

BLM SHROOM3 MYO5A SEPTIN5 PPP1R9A CHD1 ATP9A SPTY2D1 CASK RAD21

5.61e-041497671031527615
Pubmed

Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.

AKAP9 MYO5A USP32

7.12e-049067315033168
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

AHRR MYO5B YBEY LRP2

7.62e-0421267419521566
Pubmed

PTEN identified as important risk factor of chronic obstructive pulmonary disease.

BLM AHRR MYO5A MTHFR AKR1C4

7.83e-0437467519625176
Pubmed

Conformation-specific binding of alpha-synuclein to novel protein partners detected by phage display and NMR spectroscopy.

SEPTIN4 USP47

8.24e-042267217893145
Pubmed

Identification of Modifier Genes in a Mouse Model of Gaucher Disease.

ADK ITPR3

8.24e-042267227568557
Pubmed

Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.

BLM AHRR MYO5A MTHFR AKR1C4

8.51e-0438167518676680
Pubmed

Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.

BLM AHRR MYO5A MTHFR AKR1C4

8.61e-0438267519170196
Pubmed

cDNAs with long CAG trinucleotide repeats from human brain.

KMT2D CASK

9.01e-04236729225980
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

BLM CHD1 SPTY2D1 RAD21

9.04e-0422267437071664
Pubmed

Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.

TMEM67 MYO5A ATP9A

9.67e-0410067326073538
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

TMEM67 LRP2 DNAH5

9.67e-0410067325807483
Pubmed

Upregulation of imprinted genes in mice: an insight into the intensity of gene expression and the evolution of genomic imprinting.

PPP1R9A HECTD4

9.82e-042467220168089
Pubmed

Avoiding mouse traps in schizophrenia genetics: lessons and promises from current and emerging mouse models.

SEPTIN5 MTHFR

9.82e-042467221821099
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ROBO2 DNAH5 PCDH18

9.95e-0410167310997877
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

SEPTIN8 MYO5A SEPTIN4 DYNC1LI1

1.05e-0323167416452087
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

AHRR PPP1R9A ASAP1

1.05e-0310367310574462
Pubmed

Holoprosencephaly Overview

KMT2D RAD21

1.07e-032567220301702
Pubmed

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.

SEPTIN8 MYO5A SEPTIN5 PPP1R9A ACTN4

1.09e-0340367530562941
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

SEPTIN8 KCNA6 ROBO2 GNAZ ATP9A

1.12e-0340567538187761
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AKAP9 KIAA0232 PPP1R9A ATP9A ASAP1

1.14e-0340767512693553
Pubmed

Stage-specific changes in gene expression in acutely isolated mouse CNS progenitor cells.

SEPTIN8 ASAP1

1.15e-032667215890332
Pubmed

Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice.

PIK3C2G AKR1C4

1.24e-032767223471215
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FAM89A SHROOM3 KMT2D MTHFR HECTD4 GNAZ CDC14B ITPR3

1.26e-03110567835748872
Pubmed

Genetic link between renal birth defects and congenital heart disease.

TMEM67 LRP2

1.34e-032867227002738
InteractionAGAP2 interactions

LNX2 MYO5A SEPTIN5 SACS PPP1R9A DYNC1LI1 ACTN4 GNAZ ASAP1

3.09e-08210679int:AGAP2
InteractionSEPTIN1 interactions

SEPTIN8 SEPTIN5 SEPTIN4 RAD21

1.64e-0546674int:SEPTIN1
Cytoband13q12.2

LNX2 RNF6

2.81e-041767213q12.2
GeneFamilySeptins

SEPTIN8 SEPTIN5 SEPTIN4

4.93e-0613483732
GeneFamilyMyosins, class V

MYO5A MYO5B

2.07e-0534821100
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

AKAP9 KCNA6 SACS PPP1R9A ITPR3

1.15e-04181485694
GeneFamilyPDZ domain containing

SHROOM3 LNX2 PPP1R9A CASK

7.01e-041524841220
GeneFamilyAtaxins|Trinucleotide repeat containing

KMT2D CASK

1.99e-0325482775
GeneFamilyPotassium voltage-gated channels

KCNA6 KCNA10

5.05e-0340482274
GeneFamilyDNAJ (HSP40) heat shock proteins|C2 tensin-type domain containing

SACS DNAJC3

7.50e-0349482584
GeneFamilyUbiquitin specific peptidases

USP32 USP47

9.70e-0356482366
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

ADK SHROOM3 LNX2 MYO5B PPP1R9A DNAH5

3.97e-07188676707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADK SHROOM3 LNX2 MYO5B PPP1R9A ITPR3

4.49e-0719267629f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SHROOM3 LNX2 NALF1 PPP1R9A DNAH5 ITPR3

4.49e-07192676cc9911e182a289779a2612bc213daae5607689e7
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

ADK SHROOM3 LNX2 MYO5B PPP1R9A DNAH5

4.49e-07192676efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADK SHROOM3 LNX2 MYO5B PPP1R9A DNAH5

4.92e-071956769406866f99555198a9be311fbd65751b70f35446
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SHROOM3 MYO5A MYO5B PIK3C2G PPP1R9A LRP2

5.22e-0719767622b26bac3a99b20c73bfa6e6f81026d064eaa9e8
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYO5B PIK3R3 ACTN4 MYBL1 ITPR3

3.25e-061516750cc2f4aec3dae4603fa831f22c40f897e68b34e2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYO5B PIK3R3 ACTN4 MYBL1 ITPR3

3.25e-06151675b545823113a3450c5f841f7de48bf0937593544f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADK SHROOM3 NALF1 PPP1R9A DNAH5

5.17e-06166675c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADK SHROOM3 LNX2 MYO5B PPP1R9A

7.45e-06179675cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellFrontal_cortex-Neuronal-Excitatory|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

RASGRP1 ATF6 MYO5B PPP1R9A GNAZ

8.52e-061846756e17c8151d6dc543de16d804db956c63c3fda414
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NALF1 MYO5A PIK3C2G PPP1R9A ROBO2

8.75e-06185675d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADK NID2 SHROOM3 SEPTIN4 PCDH18

8.75e-06185675b1e84228c95be8ccf7c3c1afb66b71ffb93cf61e
ToppCellP15-Mesenchymal-developing_mesenchymal_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADK NID2 SHROOM3 SEPTIN4 PCDH18

8.98e-06186675db9b67066fc003c7995ec205d15176bf40c97add
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADK NALF1 MYO5B DNAH5 ITPR3

9.21e-0618767587b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MYO5A MYO5B PIK3C2G PPP1R9A LRP2

9.21e-06187675db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADK NALF1 MYO5B DNAH5 ITPR3

9.21e-0618767542a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADK NALF1 MYO5B DNAH5 ITPR3

9.21e-0618767564afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

SHROOM3 LNX2 MYO5B PPP1R9A DNAH5

9.45e-06188675c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Striatum / BrainAtlas - Mouse McCarroll V32

MYT1L RASGRP1 AKAP9 MYO5B PPP1R9A

9.45e-06188675e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RASGRP1 MYO5A PIK3C2G PPP1R9A ROBO2

9.70e-06189675fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADK RASGRP1 SHROOM3 PIK3C2G PPP1R9A

1.02e-051916753e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellfacs-Tongue-nan-18m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEPTIN8 FAM89A SEPTIN5 MYO5B PIK3R3

1.02e-0519167502f24202f9fdd46c648265a5b3b6f9066aa009fc
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADK SHROOM3 LNX2 PPP1R9A ITPR3

1.02e-05191675ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADK SHROOM3 LNX2 MYO5B PPP1R9A

1.02e-05191675e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

ADK SHROOM3 LNX2 MYO5B PPP1R9A

1.05e-05192675499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

SHROOM3 NALF1 PPP1R9A LRP2 DNAH5

1.05e-0519267506013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell11.5-Airway-Epithelial-Bud_tip_progenitor|Airway / Age, Tissue, Lineage and Cell class

NID2 MYO5A PIK3C2G PPP1R9A ITPR3

1.07e-05193675f0a07bb221a497a9f7cc706045d5205269be4515
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADK SHROOM3 MYO5B PPP1R9A ITPR3

1.07e-05193675a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADK RASGRP1 SHROOM3 PIK3C2G PPP1R9A

1.10e-0519467504bfc555743f7d8821439d05ae442d15e9886c59
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADK SHROOM3 LNX2 MYO5B PPP1R9A

1.10e-0519467553f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADK RASGRP1 SHROOM3 PIK3C2G PPP1R9A

1.10e-0519467569bff17df4a760ccf081cf52ff04af02c14f448d
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MYO5A MYO5B PIK3C2G PPP1R9A LRP2

1.10e-05194675c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MYO5A MYO5B PIK3C2G PPP1R9A LRP2

1.13e-05195675f08e41706680881ebd0afcd08a02f8ac0089f04e
ToppCellPCW_10-12-Epithelial|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SHROOM3 MYO5B PIK3C2G PPP1R9A LRP2

1.16e-051966759bfb31ff3e4f2c0a9405c418c86bfec5dbca23e2
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MYO5A MYO5B PIK3C2G PPP1R9A LRP2

1.19e-051976756852a8ec1397811bbdd1fc625c52ed4fa75a931e
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADK SHROOM3 LNX2 MYO5B PPP1R9A

1.24e-051996755f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADK SHROOM3 LNX2 MYO5B PPP1R9A

1.24e-051996758587bd98de7767a575088afbea07a1feb4516b9b
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADK SHROOM3 LNX2 MYO5B PPP1R9A

1.24e-051996755cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellLPS-IL1RA-Endothelial-Epi-like-Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEPTIN8 LRP2 ACTN4 BFSP1

5.59e-051386745f8ac8f67e34a7cf560099208e6884102532391e
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Tshz2-Syt2_(Layer_5a,_Entorhinal_cortex,_Tshz1+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KCNA10 LRP2 STK31

6.25e-0551673adc73d6909d75ad432aef884dae540b7e48cecd6
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RASGRP1 MYO5A BFSP1 RAD21

6.42e-051436748f897278f9ccc82ae35e4f30c5f930b2a3eb509d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SHROOM3 NALF1 MYO5B DNAH5

9.68e-051596748680b054622f573a82b1625fb93c2d5db81d1034
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RASGRP1 NALF1 MYO5A PIK3C2G

1.04e-04162674285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCelldroplet-Thymus-nan-21m-Myeloid-Plasma_cells_and_B_cells|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATF6 FAM89A GNAZ GDF3

1.12e-0416567421a82a975f550080b6674750b06212205cd16742
ToppCellControl|World / group, cell type (main and fine annotations)

SHROOM3 MYO5B PPP1R9A LRP2

1.20e-04168674a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L PIK3C2G LRP2 DNAH5

1.22e-0416967412bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

NID2 SACS LRP2 ROBO2

1.31e-0417267436a96714a0eb6ac438648135336c9791881ddadb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM89A SACS MTHFR GAS8

1.34e-041736742b448acd5e584f24567204c31b8d74715e92f32a
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM89A SACS MTHFR GAS8

1.34e-041736745086edc29c5a6137ca09877929a1317f9739c801
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMEM67 PPP1R9A ACTN4 ATP9A

1.40e-041756740c6cf88818037bef67211c1a8fcb1e7d47711c1d
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP9 GVINP1 CCDC82 CHD1

1.49e-0417867401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellCOVID-19-Epithelial_cells-AT1|COVID-19 / group, cell type (main and fine annotations)

SHROOM3 LNX2 MYO5B PPP1R9A

1.53e-04179674a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCellMesenchymal_cells-Chondrocytes|Mesenchymal_cells / Lineage and Cell class

BLM NID2 FAM89A KCNA6

1.56e-041806746e399368430ef3afa9ce1ef0ed90f614ccef9987
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 FAM89A AHRR KCNA6

1.59e-041816740b1e7335648823b1d83bdfa878ccd44efe7bba9a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RASGRP1 SHROOM3 PIK3C2G PPP1R9A

1.59e-04181674aa233b652921848af2257cc3687a7a09c3acfb67
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NALF1 ROBO2 BFSP1 ITPR3

1.59e-0418167422363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

ADK SHROOM3 PPP1R9A DNAH5

1.59e-04181674c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

SHROOM3 LNX2 PPP1R9A LRP2

1.66e-041836748e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

SHROOM3 LNX2 MYO5B PPP1R9A

1.66e-04183674942530449e9c6583705eeb8f6f12621daea57252
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM67 SHROOM3 ATP9A DNAH5

1.66e-0418367458847e8f3a7ce3e33adba9477bcd55e769a64a90
ToppCellfacs-Trachea-24m-Epithelial-glandular_epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SHROOM3 MYO5B PPP1R9A LRP2

1.70e-0418467461caaa31975e05c9a6512079c791fed5a9e2d39f
ToppCellfacs-Trachea-24m-Epithelial-glandular_epithelial-lung_secretory_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SHROOM3 MYO5B PPP1R9A LRP2

1.70e-0418467403da0f0f89f1ca5a3ccca1e22972f3129464e68e
ToppCellfacs-Trachea-24m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SHROOM3 MYO5B PPP1R9A LRP2

1.70e-041846749ed2a65a4ca0ebbbb89ace61027522f93369843d
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADK NID2 SHROOM3 PCDH18

1.70e-0418467423c24ab5786af33d605bc445d06117b9da6c6331
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SHROOM3 NALF1 PPP1R9A DNAH5

1.70e-04184674102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MYO5B PPP1R9A LRP2 ITPR3

1.70e-04184674fa4915b0498f3069fd5ef497286445528f75187e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADK SHROOM3 NALF1 PPP1R9A

1.73e-0418567498b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

ADK SHROOM3 PPP1R9A DNAH5

1.73e-04185674cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADK SHROOM3 PPP1R9A DNAH5

1.77e-041866742ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BLM FAM89A MYO5B ROBO2

1.77e-0418667496f6603cc75fa1ffc2a2fdb94ec0ec09498e540a
ToppCellControl-Epithelial-Club|World / Disease state, Lineage and Cell class

SHROOM3 LNX2 MYO5B PPP1R9A

1.77e-041866749798428691408e17ff2af2fe2d1b345f074d67e4
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MYO5B PIK3C2G PPP1R9A LRP2

1.77e-04186674bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 MYO5B PPP1R9A LRP2

1.77e-04186674b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellCOPD-Epithelial-Club|World / Disease state, Lineage and Cell class

SHROOM3 LNX2 MYO5B PPP1R9A

1.77e-041866743006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

ADK SHROOM3 PPP1R9A DNAH5

1.81e-0418767481cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SHROOM3 PIK3C2G PPP1R9A ITPR3

1.81e-041876745df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ROBO2 PCDH18 SPTY2D1 RAD21

1.81e-04187674173f029dcf32af008f517912f6d110a33a9e98cf
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM89A NALF1 DNAH5 CASK

1.84e-04188674a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM89A NALF1 DNAH5 CASK

1.84e-04188674c8530c9ff98666c64a94683261af4288cb790a7e
ToppCellP28-Mesenchymal-developing_mesenchymal_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NID2 SHROOM3 SEPTIN4 PCDH18

1.84e-04188674e7681efb4d2de7f1d8a89552fff76a829376bf1b
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B PIK3C2G PPP1R9A LRP2

1.88e-041896745d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NALF1 ACTN4 DNAH5 CASK

1.88e-041896748c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellSupraBC-Differ-KC|World / shred by cell class for mouse tongue

SEPTIN8 SEPTIN5 MYO5B PIK3R3

1.88e-041896746412741b88e241304033b41effca0c77a374d907
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NALF1 ACTN4 DNAH5 CASK

1.88e-041896745d902a4660a27548764bf04c6de152b565da835c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 MYO5A PIK3C2G PPP1R9A

1.88e-04189674532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PIK3C2G PPP1R9A LRP2 MYBL1

1.88e-04189674c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BLM FAM89A MYO5B ROBO2

1.92e-0419067426843ec1d19ac85a50990705353b802745d33e4d
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B PIK3C2G PPP1R9A LRP2

1.92e-04190674625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellCOPD-Epithelial-Club|COPD / Disease state, Lineage and Cell class

SHROOM3 MYO5B PPP1R9A DNAH5

1.96e-04191674c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCell368C-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CCDC82 GAS8 USP47 GNPAT

1.96e-04191674d7920f4a602b50d0ef064eb47001e71939695ed2
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B PPP1R9A LRP2 DNAH5

1.96e-0419167460ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

ADK SHROOM3 PPP1R9A LRP2

1.96e-04191674276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

ADK SHROOM3 MYO5B PPP1R9A

1.96e-04191674d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B PPP1R9A LRP2 MYBL1

2.00e-0419267425378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellCOPD-Epithelial|COPD / Disease state, Lineage and Cell class

SHROOM3 MYO5B PPP1R9A DNAH5

2.00e-041926740644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

SHROOM3 PPP1R9A LRP2 ITPR3

2.00e-0419267458c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B PPP1R9A LRP2 ITPR3

2.00e-04192674d3634574b2e8d2ded6446969361b70761b331aea
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B PIK3C2G PPP1R9A LRP2

2.00e-04192674b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADK PIK3C2G PPP1R9A ITPR3

2.00e-04192674fb2f0e897228f808d9ff734ad05e9b49dc38fa50
Diseasesensory perception of bitter taste

KCNA10 DYNC1LI1 ROBO2

2.80e-0526673GO_0050913
Diseasecircadian rhythm

AKAP9 ROBO2 STK31 SPTY2D1 ASAP1

3.54e-05163675EFO_0004354
Diseasewaist circumference

SEC16B TYW1B PPP1R9A HECTD4 ACTN4 DNAH5

4.31e-04429676EFO_0004342
Diseaseanemia (is_implicated_in)

GH1 MTHFR

4.54e-0414672DOID:2355 (is_implicated_in)
Diseasehearing loss

NID2 AHRR PIK3R3

4.83e-0467673EFO_0004238
DiseaseLymphoma, Large-Cell, Follicular

KMT2D MTHFR

5.23e-0415672C0079745
DiseaseLymphoma, Small Cleaved-Cell, Follicular

KMT2D MTHFR

5.23e-0415672C0079765
DiseaseLymphoma, Mixed-Cell, Follicular

KMT2D MTHFR

5.23e-0415672C0079758
DiseaseSitus ambiguus

SHROOM3 DNAH5

5.23e-0415672C0266642
DiseaseLymphoma, Follicular, Grade 2

KMT2D MTHFR

5.23e-0415672C1956132
DiseaseLymphoma, Follicular, Grade 3

KMT2D MTHFR

5.23e-0415672C1956131
DiseaseLymphoma, Follicular, Grade 1

KMT2D MTHFR

5.23e-0415672C1956130
Diseasepreeclampsia, hypertension, pregnancy-induced

MTHFR ACTN4

5.97e-0416672EFO_0000668, MONDO_0024664
Diseasesquamous cell carcinoma (is_implicated_in)

RNF6 MTHFR

7.59e-0418672DOID:1749 (is_implicated_in)
Diseasehemifacial microsomia

NID2 SHROOM3

8.47e-0419672MONDO_0015398
DiseaseLymphoma, Follicular

KMT2D MTHFR

9.40e-0420672C0024301
Diseasetype 1 diabetes mellitus (is_implicated_in)

GH1 MTHFR ITPR3

9.67e-0485673DOID:9744 (is_implicated_in)
Diseaseerosive tooth wear measurement

MYT1L NALF1 ROBO2

1.14e-0390673EFO_0009331
DiseaseImmunologic Deficiency Syndromes

BLM RASGRP1

1.25e-0323672C0021051
Diseaselung small cell carcinoma (is_implicated_in)

KMT2D MTHFR

1.85e-0328672DOID:5409 (is_implicated_in)
DiseaseCone-Rod Dystrophy 2

ATF6 CACNA2D4

1.98e-0329672C3489532
DiseaseNeural Tube Defects

SHROOM3 MTHFR

2.12e-0330672C0027794
Diseasemean platelet volume

LNX2 NALF1 MYO5A PCDHGB2 MTHFR KIAA0232 ACTN4 ASAP1

2.13e-031020678EFO_0004584
Diseaseimmature platelet fraction

SEPTIN5 KIAA0232 ASAP1

2.25e-03114673EFO_0009187
Diseaseprogressive supranuclear palsy

PIK3C2G ASAP1

2.26e-0331672MONDO_0019037

Protein segments in the cluster

PeptideGeneStartEntry
EYIFHQCKENEDYND

YBEY

96

P58557
HQNIYDYIHVDDRQD

AHRR

156

A9YTQ3
FRHIDSAYLYNNEEQ

AKR1C4

46

P17516
NFEVNYQELQEEYAC

AKAP9

856

Q99996
ELQDYRYEVQDFQEN

AKAP9

1241

Q99996
AEAHVDAHYYEQNEQ

ADK

121

P55263
NFNSFNLDEYEHYEK

CDC14B

196

O60729
NLDEYEHYEKAENGD

CDC14B

201

O60729
EEENFDNYWEYLHNS

GVINP1

2136

Q7Z2Y8
NYDHDQDGYISQEEF

RASGRP1

481

O95267
IAQELNELDYYDSHN

ACTN4

476

O43707
ETYENNFDNLDFDLD

ATF6

51

P18850
NFNSFNLDEYEHYEK

CDC14C

166

A4D256
NLDEYEHYEKAENGD

CDC14C

171

A4D256
VEYYNCQQELTDDLH

CHD1

371

O14646
YDEAIQDYETAQEHN

DNAJC3

356

Q13217
INHLEYEDQYKDDNF

RAD21

206

O60216
EEDHSQFYLNQLLEF

PIK3C2G

381

O75747
AQEEEEDPLAYYENH

ITPR3

2106

Q14573
YEEDDFDNVLNHLND

PCDH18

1096

Q9HCL0
YAHYFDLTIINNEID

CASK

886

O14936
YIHDNYFLVNLVDND

MTHFR

611

P42898
HLYNYQNEVDDDLVC

LNX2

36

Q8N448
YLYLNVHDEDRDDQT

DYNC1LI1

101

Q9Y6G9
YQDNNDNVILRHYED

GDF3

341

Q9NR23
LHDSYDYDLQEQEND

KIAA0232

66

Q92628
SLQRYHLNDNEYFDL

PCDHGB2

166

Q9Y5G2
EYLQDEEYIQAVDYD

LRP2

4076

P98164
LAEEQYQDFEARYVQ

ATP9A

606

O75110
NFQYQEEHAEEYDLL

HECTD4

926

Q9Y4D8
NEDNLDYYDVNEEEA

NID2

311

Q14112
NYFYHRETENEEKQN

KCNA10

461

Q16322
YFINEEDENLPHYDE

PIK3R3

341

Q92569
QLEEYLNFADYFQEE

CCDC82

526

Q8N4S0
EYHLEDNAAYYLNDL

GNAZ

146

P19086
FNYFYHRETEQEEQG

KCNA6

461

P17658
DEDLYINANDQAIAY

BLM

1156

P54132
YLLSEEEDHFSEEQY

GNPAT

586

O15228
ADLNHEFNESLVFDY

CACNA2D4

151

Q7Z3S7
AHECYDDEIQLYNEQ

BFSP1

256

Q12934
NRTYHFQAEDEQDYV

ASAP1

391

Q9ULH1
LNLEEYYFEQHRANH

NSMAF

26

Q92636
SDEDYYQFQHILLEI

SACS

1241

Q9NZJ4
DDDLQYADHDYEVPQ

MYBL1

11

P10243
EVFLQDCHQFYLDYD

DNAH5

1336

Q8TE73
DVYLEYTDENQHQYI

TMEM67

396

Q5HYA8
AEYIDQQFEQYFRDE

SEPTIN4

226

O43236
TDYVDQQFEQYFRDE

SEPTIN5

126

Q99719
FFDEEEEYFQEQNSL

FAM89A

141

Q96GI7
REEAYYQFINELNDE

RNF6

36

Q9Y252
NYLSEEQLQDYQHFV

SHROOM3

1911

Q8TF72
FLEYNHAESEQEYEE

SPTY2D1

131

Q68D10
NNVFQEIYHEREEYE

STK31

676

Q9BXU1
CYQDVDKDIHDYEFQ

ZNF761

86

Q86XN6
YNGENAQDQFEYELE

TMEM11

36

P17152
LDYHIYEEDINISSN

USP47

1191

Q96K76
LHQLAFDTYQEFEEA

GH1

46

P01241
VDYIDAQFENYLQEE

SEPTIN8

121

Q92599
ELEHYAVEQQENGYD

ROBO2

1086

Q9HCK4
EEQEEENDYINSYFE

POLR3G

191

O15318
YREQKYLDEHHYENQ

SEC16B

151

Q96JE7
YNSENYLTLLDDEDH

USP32

671

Q8NFA0
IDYNRFQELIQEYED

TYW1B

606

Q6NUM6
HEEAFTDIKNYYNDI

GAS8

226

O95995
EELTYDYQFDFEDDQ

KMT2D

5506

O14686
EAYQDYDHHAQEKYE

NALF1

266

B1AL88
FQAEEERNYHIFYQL

MYO5A

251

Q9Y4I1
FQADDERNYHIFYQL

MYO5B

251

Q9ULV0
KDDNNNDEYDNYDEL

MYT1L

186

Q9UL68
LLEQHYAQYDADDDE

PPP1R9A

616

Q9ULJ8