Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainBNIP2

BNIP2 ATCAY BNIPL

1.39e-074623PF12496
DomainBcl2-/adenovirus-E1B

BNIP2 ATCAY BNIPL

1.39e-074623IPR022181
DomainCRAL_TRIO_2

BNIP2 ATCAY BNIPL

7.50e-0612623PF13716
DomainFAM21

WASHC2C WASHC2A

1.08e-052622IPR027308
DomainFAM21/CAPZIP

WASHC2C WASHC2A

3.25e-053622IPR029341
DomainCAP-ZIP_m

WASHC2C WASHC2A

3.25e-053622PF15255
DomainCRAL_TRIO

BNIP2 ATCAY BNIPL

4.44e-0521623PF00650
Domain-

BNIP2 ATCAY BNIPL

5.88e-05236233.40.525.10
DomainSEC14

BNIP2 ATCAY BNIPL

7.61e-0525623SM00516
DomainCRAL_TRIO

BNIP2 ATCAY BNIPL

9.63e-0527623PS50191
DomainCRAL-TRIO_dom

BNIP2 ATCAY BNIPL

1.08e-0428623IPR001251
DomainEGF_LAM_2

CELSR1 LAMA4

4.44e-0330622PS50027
DomainEGF_LAM_1

CELSR1 LAMA4

4.44e-0330622PS01248
DomainLaminin_EGF

CELSR1 LAMA4

6.01e-0335622PF00053
DomainEGF_Lam

CELSR1 LAMA4

6.01e-0335622SM00180
DomainLAM_G_DOMAIN

CELSR1 LAMA4

7.06e-0338622PS50025
DomainLaminin_EGF

CELSR1 LAMA4

7.06e-0338622IPR002049
DomainLaminin_G_2

CELSR1 LAMA4

7.80e-0340622PF02210
DomainLamG

CELSR1 LAMA4

9.38e-0344622SM00282
PathwayPID_INTEGRIN1_PATHWAY

SPP1 LAMA4 NID1 ITGA9

2.58e-0566374M18
PathwayPID_INTEGRIN_A9B1_PATHWAY

VEGFC SPP1 ITGA9

3.68e-0525373M118
Pubmed

Identification of a DNA sequence responsible for binding of the 1,25-dihydroxyvitamin D3 receptor and 1,25-dihydroxyvitamin D3 enhancement of mouse secreted phosphoprotein 1 (SPP-1 or osteopontin) gene expression.

SPP1 VDR

3.33e-0626422175918
Pubmed

Vitamin D Receptor Promotes Global Nucleotide Excision Repair by Facilitating XPC Dissociation from Damaged DNA.

XPC VDR

3.33e-06264233524369
Pubmed

Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).

WASHC2C WASHC2A

3.33e-06264220827171
Pubmed

FAM21 is critical for TLR2/CLEC4E-mediated dendritic cell function against Candida albicans.

WASHC2C WASHC2A

3.33e-06264236717248
Pubmed

Osteopontin undergoes polymerization in vivo and gains chemotactic activity for neutrophils mediated by integrin alpha9beta1.

SPP1 ITGA9

3.33e-06264221321126
Pubmed

Vitamin D receptor activators induce an anticalcific paracrine program in macrophages: requirement of osteopontin.

SPP1 VDR

3.33e-06264219948844
Pubmed

Laminin Subunit Alpha-4 and Osteopontin Are Glioblastoma-Selective Secreted Proteins That Are Increased in the Cerebrospinal Fluid of Glioblastoma Patients.

SPP1 LAMA4

3.33e-06264232628487
Pubmed

Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis.

SPP1 MERTK

3.33e-06264231221805
Pubmed

Identification of a novel Rev-interacting cellular protein.

WASHC2C WASHC2A

3.33e-06264215847701
Pubmed

MDM2 binds and inhibits vitamin D receptor.

MDM2 VDR

3.33e-06264225969952
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PPP1R26 SOX4 CELSR1 RHBDF1 BICRA CHD8 ICE1 ZC3H7B WASHC2A MED13 CEP170B

5.04e-061105641135748872
Pubmed

α9β1 integrin-mediated signaling serves as an intrinsic regulator of pathogenic Th17 cell generation.

SPP1 ITGA9

9.99e-06364222039306
Pubmed

Vitamin D receptor agonists increase klotho and osteopontin while decreasing aortic calcification in mice with chronic kidney disease fed a high phosphate diet.

SPP1 VDR

9.99e-06364222932118
Pubmed

Abnormal XPD-induced nuclear receptor transactivation in DNA repair disorders: trichothiodystrophy and xeroderma pigmentosum.

SPP1 VDR

9.99e-06364223232694
Pubmed

Elevated potassium outward currents in hyperoxia treated atrial cardiomyocytes.

KCNA6 KCNIP2

9.99e-06364229139549
Pubmed

Polymeric osteopontin employs integrin alpha9beta1 as a receptor and attracts neutrophils by presenting a de novo binding site.

SPP1 ITGA9

9.99e-06364219346516
Pubmed

Regulation of XPC Binding Dynamics and Global Nucleotide Excision Repair by p63 and Vitamin D Receptor.

XPC VDR

9.99e-06364236877866
Pubmed

The BNIP-2 and Cdc42GAP homology/Sec14p-like domain of BNIP-Salpha is a novel apoptosis-inducing sequence.

BNIP2 BNIPL

9.99e-06364211741952
Pubmed

A novel cryptic binding motif, LRSKSRSFQVSDEQY, in the C-terminal fragment of MMP-3/7-cleaved osteopontin as a novel ligand for α9β1 integrin is involved in the anti-type II collagen antibody-induced arthritis.

SPP1 ITGA9

9.99e-06364225545242
Pubmed

Osteopontin mediates macrophage chemotaxis via α4 and α9 integrins and survival via the α4 integrin.

SPP1 ITGA9

9.99e-06364223192608
Pubmed

The integrin alpha(9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin.

SPP1 ITGA9

9.99e-06364210593924
Pubmed

Nidogen 1 and Nuclear Protein 1: novel targets of ETV5 transcription factor involved in endometrial cancer invasion.

NID1 NUPR1

9.99e-06364225924802
Pubmed

Osteopontin, Bone Morphogenetic Protein-4, and Vitamin D Receptor Gene Polymorphisms in the Susceptibility and Clinical Severity of Spinal Tuberculosis.

SPP1 VDR

9.99e-06364228376475
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

SOX4 LRFN4 SAFB WASHC2C NID1 CHD8 MERTK WASHC2A MED13 CEP170B PSRC1

1.23e-051215641115146197
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

FSIP2 MIS18BP1 GTF3C1 PHF20L1 SENP6 CHD8 XPC PHF8

1.56e-0560864836089195
Pubmed

The lymphangiogenic vascular endothelial growth factors VEGF-C and -D are ligands for the integrin alpha9beta1.

VEGFC ITGA9

2.00e-05464215590642
Pubmed

Pathological MAPK activation-mediated lymphatic basement membrane disruption causes lymphangiectasia that is treatable with ravoxertinib.

LAMA4 NID1

2.00e-05464236073544
Pubmed

Functional interaction of osteogenic transcription factors Runx2 and Vdr in transcriptional regulation of Opn during soft tissue calcification.

SPP1 VDR

2.00e-05464223644099
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

MIS18BP1 WASHC2C MAP4K3 ECD CILK1 PHF8 WASHC2A CEP170B FTSJ3

2.54e-0585364928718761
Pubmed

Induction of SOX4 by DNA damage is critical for p53 stabilization and function.

SOX4 MDM2

3.32e-05564219234109
Pubmed

Polydom/SVEP1 is a ligand for integrin α9β1.

SPP1 ITGA9

3.32e-05564222654117
Pubmed

Cycling and early pregnant endometrium as a site of regulated expression of the vitamin D system.

SPP1 VDR

3.32e-05564216720713
Pubmed

TXNIP interacts with hEcd to increase p53 stability and activity.

ECD MDM2

3.32e-05564223880345
Pubmed

CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis.

CHD8 MDM2

3.32e-05564219151705
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

SAFB WASHC2C GTF3C1 CHD8 PSRC1 STAT5B FTSJ3

3.87e-0550364716964243
Pubmed

Effects of glucokinase haploinsufficiency on the pancreatic β-cell mass and function of long-term high-fat, high-sucrose diet-fed mice.

SPP1 ANKRD34C NUPR1

4.42e-053764339305123
Pubmed

Nucleotide excision repair gene polymorphisms may predict acute toxicity in patients treated with chemoradiotherapy for bladder cancer.

XPC MDM2

4.98e-05664221047201
Pubmed

BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis.

BNIP2 BNIPL

4.98e-05664212901880
Pubmed

XPC promotes MDM2-mediated degradation of the p53 tumor suppressor.

XPC MDM2

4.98e-05664224258024
Pubmed

Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning.

SPP1 VDR

4.98e-0566429241280
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

SAFB BICRA U2SURP SENP6 BEND3 CHD8 ICE1 ESF1 FTSJ3

6.03e-0595464936373674
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SAFB WASHC2C GTF3C1 SENP6 XPC PHF8 MED13 ESF1

8.56e-0577464815302935
Pubmed

Distinct structural requirements for binding of the integrins alphavbeta6, alphavbeta3, alphavbeta5, alpha5beta1 and alpha9beta1 to osteopontin.

SPP1 ITGA9

9.27e-05864216005200
Pubmed

A FAM21-containing WASH complex regulates retromer-dependent sorting.

WASHC2C WASHC2A

9.27e-05864219922874
Pubmed

Genetics of lymphatic anomalies.

VEGFC ITGA9

9.27e-05864224590274
Pubmed

Gene polymorphisms, bone mineral density and bone mineral content in young children: the Iowa Bone Development Study.

SPP1 VDR

9.27e-05864212879219
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

NFE2L3 VPS9D1 DCHS2 APPL2 CNST SENP6 XPC MERTK MED13 STAT5B

1.13e-041285641035914814
Pubmed

Dachsous1-Fat4 Signaling Controls Endothelial Cell Polarization During Lymphatic Valve Morphogenesis-Brief Report.

CELSR1 ITGA9

1.19e-04964228705793
Pubmed

Primary cellular meningeal defects cause neocortical dysplasia and dyslamination.

LAMA4 NID1

1.49e-041064220976766
Pubmed

Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18.

VEGFC SPP1

1.49e-041064211937493
Pubmed

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.

SAFB XPC ESF1 FTSJ3

1.64e-0414864432538781
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SAFB MIS18BP1 GTF3C1 MAP4K3 U2SURP CHD8 XPC PHF8 ESF1 FTSJ3

1.72e-041353641029467282
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

GTF3C1 PHF20L1 CHD8 XPC

1.73e-0415064428242625
Pubmed

The vitamin D receptor is not required for fetal mineral homeostasis or for the regulation of placental calcium transfer in mice.

SPP1 VDR

1.81e-041164215741244
Pubmed

Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung.

LAMA4 NID1

1.81e-041164212051813
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

MIS18BP1 EML5 CNST DNAH11

1.82e-0415264434299191
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

EML5 BICRA BEND3 CHD8 XPC PHF8 MDM2 CEP170B FTSJ3

1.97e-04111664931753913
Pubmed

The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

WASHC2C WASHC2A

2.17e-041264219922875
Pubmed

Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour.

WASHC2C WASHC2A

2.17e-041264227390154
Pubmed

Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.

LAMA4 NID1

2.17e-041264216750824
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

DNAAF8 GTF3C1 SPP1 BEND3 CHD8 VDR

2.25e-0446964627634302
Pubmed

Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.

SOX4 BNIP2 MIS18BP1 PHF20L1

2.49e-0416564416107646
Pubmed

Basement membranes in skin are differently affected by lack of nidogen 1 and 2.

LAMA4 NID1

2.57e-041364218356808
Pubmed

Gene array identification of Ipf1/Pdx1-/- regulated genes in pancreatic progenitor cells.

SPP1 PTF1A

2.57e-041364218036209
Pubmed

Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways.

U2SURP MDM2

2.57e-041364220858735
Pubmed

The transcription factor Sry-related HMG box-4 (SOX4) is required for normal renal development in vivo.

SOX4 NID1

2.57e-041364223559562
Pubmed

Human transcription factor protein interaction networks.

SOX4 GTF3C1 BICRA BEND3 CHD8 PHF8 MDM2 WASHC2A STAT5B FTSJ3

2.66e-041429641035140242
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

NFE2L3 SAFB GTF3C1 PHF20L1 U2SURP ECD BEND3 XPC MED13 ESF1

2.86e-041442641035575683
Pubmed

EMILIN1-α4/α9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation.

NID1 ITGA9

2.99e-041464221949412
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

SAFB WASHC2C U2SURP ECD SENP6 ICE1 ESF1 FTSJ3

3.07e-0493464833916271
Pubmed

Basement membrane composition in the early mouse embryo day 7.

LAMA4 NID1

3.45e-041564215895400
Pubmed

Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling.

WASHC2C WASHC2A

3.45e-041564228892079
Pubmed

Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.

LAMA4 NID1

3.45e-041564210625553
Pubmed

A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy.

VEGFC ITGA9

3.45e-041564223299940
Pubmed

Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188.

VEGFC SPP1

3.45e-041564211804779
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

CELSR1 RHBDF1 APPL2 CHD8 ICE1 XPC ZC3H7B MED13 CEP170B ESF1

3.85e-041497641031527615
Pubmed

Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.

LAMA4 NID1

3.93e-041664217948866
Pubmed

Cell-matrix signals specify bone endothelial cells during developmental osteogenesis.

SPP1 LAMA4

3.93e-041664228218908
Pubmed

Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas.

SPP1 PTF1A

3.93e-041664221266405
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

MIS18BP1 GTF3C1 SENP6 CHD8 FTSJ3

4.07e-0433964530415952
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

SPP1 LAMA4 NID1

4.25e-047964318757743
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SENP6 CHD8 ICE1 ZC3H7B GRAMD4 MED13

4.28e-0452964614621295
Pubmed

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.

MED13 VDR

4.45e-041764210235266
Pubmed

Laminin α1 is essential for mouse cerebellar development.

LAMA4 NID1

4.45e-041764221983115
Pubmed

Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes.

GTF3C1 CHD8

4.45e-041764221653943
Pubmed

LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development.

SPP1 PTF1A

4.45e-041764232350257
Pubmed

Genome-wide expression analysis of Ptf1a- and Ascl1-deficient mice reveals new markers for distinct dorsal horn interneuron populations contributing to nociceptive reflex plasticity.

PTF1A KCNIP2

5.00e-041864223616538
Pubmed

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators.

MED13 VDR

5.00e-041864210198638
Pubmed

USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier.

GTF3C1 CHD8

5.00e-041864217846119
Pubmed

Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis.

SPP1 ITGA9

5.00e-041864219686679
Pubmed

Jmjd5 functions as a regulator of p53 signaling during mouse embryogenesis.

XPC MDM2

5.00e-041864226334721
Pubmed

COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A.

WASHC2C WASHC2A

5.59e-041964225355947
Pubmed

A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation.

SPP1 PTF1A

5.59e-041964222675211
Pubmed

Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure.

VEGFC BICRA

6.20e-042064222174851
Pubmed

Transcription factors SOX4 and SOX9 cooperatively control development of bile ducts.

SOX4 SPP1

6.20e-042064226033091
Pubmed

¹H NMR metabolic profiling of plasma reveals additional phenotypes in knockout mouse models.

PRIMPOL RETREG3

6.20e-042064225849460
Pubmed

Maternal hypervitaminosis D reduces fetal bone mass and mineral acquisition and leads to neonatal lethality.

SPP1 VDR

6.84e-042164223895994
Pubmed

Osteopontin is a novel marker of pancreatic ductal tissues and of undifferentiated pancreatic precursors in mice.

SPP1 PTF1A

6.84e-042164216518820
Pubmed

N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.

CNST LPO BEND3 MDM2

6.99e-0421764434048709
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

MIS18BP1 WASHC2C SENP6 MDM2 WASHC2A CEP170B

7.44e-0458864638580884
InteractionNUP43 interactions

FSIP2 SAFB MIS18BP1 PHF20L1 SENP6 BEND3 CHD8 ICE1 XPC PHF8 NUPR1 FTSJ3

5.36e-076256412int:NUP43
InteractionPARP1 interactions

GTF3C1 SPP1 BICRA U2SURP ECD SENP6 BEND3 XPC PHF8 MERTK ZC3H7B MDM2 NUPR1 ESF1 FTSJ3

1.18e-0513166415int:PARP1
InteractionPOLR1E interactions

GTF3C1 BEND3 CHD8 ICE1 XPC PHF8 ESF1 FTSJ3

1.45e-05350648int:POLR1E
InteractionPOLR1G interactions

GTF3C1 BICRA BEND3 CHD8 ICE1 XPC PHF8 ESF1 FTSJ3

2.28e-05489649int:POLR1G
InteractionCENPA interactions

MIS18BP1 GTF3C1 SENP6 BEND3 XPC PHF8 ESF1 FTSJ3

2.47e-05377648int:CENPA
InteractionSUPT5H interactions

GTF3C1 BICRA U2SURP ICE1 PHF8 WASHC2A NUPR1 FTSJ3

4.33e-05408648int:SUPT5H
InteractionANAPC15 interactions

SAFB U2SURP ECD PHF8 ESF1

5.40e-05128645int:ANAPC15
GeneFamilyRho GTPase activating proteins|BCH domain containing

BNIP2 ATCAY BNIPL

4.05e-0774231299
GeneFamilyWASH complex

WASHC2C WASHC2A

7.86e-0564221331
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R26 KCNA6 CNST VDR

8.08e-04181424694
CoexpressionGSE27786_NKCELL_VS_NKTCELL_UP

SOX4 VPS9D1 BNIP2 SPP1 MAP4K3 PRIMPOL

9.50e-06200646M4851
ToppCellfacs-Pancreas-Exocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 RHBDF1 SPP1 PTF1A LAMA4 NUPR1

2.49e-0718264645faefd7cbeac84d2c58650530b902af6ce921f8
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VEGFC MAP4K3 LAMA4 NID1 ITGA9 NUPR1

4.08e-0719864609be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCellMild/Remission-B_naive-1|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WASHC2C ICE1 WASHC2A RETREG3

5.36e-05143644bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

DNAAF8 NFE2L3 BNIPL LAMA4

6.13e-0514864410dcbdb47cac908648d9d652c8095b536db19b8a
ToppCellControl-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WASHC2C ICE1 WASHC2A RETREG3

7.33e-051556440a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NFE2L3 EML5 BNIPL GRAMD4

7.89e-051586442ae863ccef201414b82a2ecf7cf1bbb1b0ce4a3c
ToppCellControl-B_intermediate-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WASHC2C ICE1 WASHC2A RETREG3

9.78e-05167644948504367ecf58144d9dd74d2ec531358fc4b309
ToppCell343B-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

LURAP1L LPO MED13 CEP170B

1.02e-04169644e68e6c24606fd46eca6f86bb63fa86ea17879ae2
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 SPP1 MERTK PRIMPOL

1.07e-04171644845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCellControl-B_naive-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WASHC2C ICE1 WASHC2A RETREG3

1.07e-04171644d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHBDF1 APPL2 PTF1A NUPR1

1.15e-04174644165e14cad57e90aa247dcecfaa3c2e8ff2a470ad
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHBDF1 APPL2 PTF1A NUPR1

1.15e-041746444289dfc7613db4bb3d706b9b65d06e84c0c53558
ToppCellnormal_Lung-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

NLN LRFN4 KCNIP2 VDR

1.15e-04174644e324320b52c904496e26fcecfa179b3431729ec0
ToppCelldroplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EML5 CASTOR2 FAM219A S100PBP

1.20e-0417664424b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EML5 CASTOR2 FAM219A S100PBP

1.22e-04177644f360f7099570d248531897b96e0de282e58f59e9
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX4 CELSR1 BNIPL ITGA9

1.31e-04180644b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellwk_20-22-Hematologic-Meg-ery-Platelet|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

BNIP2 CNST RTL1 PRIMPOL

1.33e-04181644724efbc200e8388829bc7d81830c2689a95fa838
ToppCellCOVID-19_Mild-NK_activated|COVID-19_Mild / Disease condition and Cell class

WASHC2C ICE1 WASHC2A RETREG3

1.39e-0418364422bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4|TCGA-Thryoid / Sample_Type by Project: Shred V9

LURAP1L DCHS2 RHBDF1 CEP170B

1.42e-04184644d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MIS18BP1 SPP1 ATCAY CEP170B

1.45e-04185644b4af9ae4c358b48357cb135b740266e1652d886a
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EML5 ATCAY KCNIP2 FAM219A

1.45e-04185644ef996f4cdbc3971c6c0460d13df64b075ab22154
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EML5 ATCAY KCNIP2 FAM219A

1.45e-04185644d51342a3979bd728a80e04126059a3fd8a0dbe3b
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 SPP1 ITGA9 NUPR1

1.51e-041876449aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LURAP1L DCHS2 LAMA4 NID1

1.51e-041876448ee3bf885897efd634c3a0567637142a9f55e693
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LURAP1L SPP1 LAMA4 ITGA9

1.54e-04188644842982de2197770f999a70083ed9fca40ac22d79
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LURAP1L SPP1 LAMA4 ITGA9

1.54e-04188644a0815eaf68eedd6e5ec4af520df80a6ab4eb0864
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LURAP1L DCHS2 LAMA4 NID1

1.64e-04191644a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LURAP1L DCHS2 LAMA4 NID1

1.64e-041916448f6d592edc32fdb901af30501d4360512334e8c2
ToppCellHippocampus-Endothelial|Hippocampus / BrainAtlas - Mouse McCarroll V32

SPP1 LAMA4 NID1 NUPR1

1.67e-0419264436deadab892d3e639a71f33697bb2d3cbbaa5372
ToppCellMesenchymal_cells-Ng2+_MSCs|World / Lineage and Cell class

SPP1 MERTK NUPR1 VDR

1.67e-041926440703b8ec6960ff975ee5a2737054db67cab016b5
ToppCell(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|World / Stress and Cell class

VEGFC SPP1 LAMA4 NUPR1

1.71e-04193644f31398dad5321a7bcb27e208bd73630e9756e897
ToppCellfacs-Liver-Non-hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA4 NID1 MERTK ITGA9

1.71e-041936448084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX4 SPP1 NUPR1 DNAH11

1.71e-04193644ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SOX4 MDM2 PSRC1 DNAH11

1.71e-04193644c3522693439c23830d8a3f20854539ccb7a666e0
ToppCell(1)_Osterolineage_cells|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SOX4 SPP1 NUPR1 VDR

1.71e-04193644035eeea9f77c4bf9cd85f07fa791b6c857be76b5
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LURAP1L LAMA4 NID1 NUPR1

1.74e-041946447b6ec45adb7ece3c8a7b78c5782413b5825effe2
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LURAP1L BNIPL CEP170B VDR

1.74e-041946440ef63abcfd057079a9a6f8b27404ff521d44845d
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA4 NID1 ITGA9 NUPR1

1.81e-0419664485507488f83d8f71b3ee2ad5e5aa0b6ad6193873
ToppCell11.5-Distal-Mesenchymal-Airway_Smooth_Muscle|Distal / Age, Tissue, Lineage and Cell class

SOX4 NID1 ITGA9 NUPR1

1.81e-0419664405530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA4 NID1 MERTK ITGA9

1.84e-04197644deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA4 NID1 MERTK ITGA9

1.84e-04197644a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCellMonocytes-NUPR1+_Monocytes|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

NLN MERTK NUPR1 GRAMD4

1.84e-041976448a058c9d9285acd7cf2fb8e34f7602a86b5d6c89
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMA4 NID1 ITGA9 NUPR1

1.84e-04197644e132f4b9deef6a565262c0aa0863cafe28f248e6
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LURAP1L LAMA4 NID1 DNAH11

1.84e-04197644fd65a9b41df618ff2a09d76dcf9f1ca3f3bdf52a
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX4 LAMA4 NID1 NUPR1

1.88e-0419864475d104eead681f6bf47c4dd24913cc768c9a1717
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX4 LAMA4 NID1 NUPR1

1.92e-041996443d8c76e3d05acf72a35ca755b51579fc3ae63562
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX4 LAMA4 NID1 NUPR1

1.92e-04199644ec74ff85d6b61013b1f785b2fca343759feb7843
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

LURAP1L LAMA4 NID1 ITGA9

1.95e-04200644c5e051f1aac8dda376c342a9932785a23450e073
ToppCellwk_15-18-Mesenchymal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

LURAP1L LAMA4 NID1 NUPR1

1.95e-042006444d484260ecbbbd9f820b445bdcc2666f6c464b73
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

LURAP1L LAMA4 NID1 ITGA9

1.95e-04200644a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

LURAP1L LAMA4 NID1 ITGA9

1.95e-0420064402cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

LURAP1L LAMA4 NID1 ITGA9

1.95e-042006449d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIS18BP1 LAMA4 NID1 PSRC1

1.95e-04200644dd5b753bb1333fa502b9d3a6d65a53a9882b2451
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

LURAP1L LAMA4 NID1 ITGA9

1.95e-04200644a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellwk_15-18-Mesenchymal-Fibroblast-intermediate_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

VEGFC LURAP1L NID1 NUPR1

1.95e-042006446461d25fd8fb52921b188f083fbe808535d3130b
ToppCellwk_08-11-Mesenchymal|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LURAP1L LAMA4 NID1 NUPR1

1.95e-0420064491416639e69621c5b36eebf061d81bccfe66f135
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

LURAP1L NFE2L3 MAP4K3 NID1

1.95e-04200644bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellwk_20-22-Mesenchymal|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LURAP1L LAMA4 NID1 NUPR1

1.95e-042006445c8557d2c414d8a8c518270f8c045b53cae45fb6
DiseaseMilroy Disease

VEGFC CELSR1

4.33e-055622C1704423
DiseaseBasal cell carcinoma

XPC STAT5B

2.36e-0411622C0007117
Diseasemyopia (is_implicated_in)

PRIMPOL VDR

5.11e-0416622DOID:11830 (is_implicated_in)
DiseaseUremia

SPP1 VDR

5.79e-0417622C0041948
Diseaseurinary bladder cancer (is_marker_for)

VEGFC SPP1 MDM2

1.50e-03107623DOID:11054 (is_marker_for)
Diseaseintelligence, response to cranial radiation therapy

DCHS2 GTF3C1

1.59e-0328622EFO_0004337, EFO_0010950
Diseasetuberculosis (is_implicated_in)

SPP1 VDR

1.59e-0328622DOID:399 (is_implicated_in)
Diseasepancreatic cancer (is_implicated_in)

SPP1 XPC ITGA9

1.71e-03112623DOID:1793 (is_implicated_in)
Diseaseneutrophil percentage of leukocytes

BNIP2 GTF3C1 BEND3 MERTK ZC3H7B STAT5B

1.76e-03610626EFO_0007990
Diseaselow density lipoprotein cholesterol measurement, phospholipid measurement

NFE2L3 PSRC1 DNAH11

2.08e-03120623EFO_0004611, EFO_0004639

Protein segments in the cluster

PeptideGeneStartEntry
SFSNLDLSEEDSDDP

VDR

201

P11473
EDDSDSELDLSKLSP

CHD8

2066

Q9HCK8
LGLDSPLTEKEDDFF

ANKRD34C

196

P0C6C1
DDFLDLAESPNASDT

GRAMD4

16

Q6IC98
DEEGFLELPSSEHLS

CASTOR2

56

A6NHX0
ASGEIPDLFSDEDVD

DNAH11

2931

Q96DT5
PGHDSDSDSELSLDE

CELSR1

2801

Q9NYQ6
LFGQEELDPDSLSDA

CEP170B

736

Q9Y4F5
LDSDDDLDFETHEPG

ECD

516

O95905
DLDFETHEPGEEASL

ECD

521

O95905
SDESDELVTDFPTDL

SPP1

126

P10451
DLTEFLDEASSPGEF

BEND3

396

Q5T5X7
ELPDSDGFLDSSEEI

MAP4K3

351

Q8IVH8
LLPSFQDSEDDDDIL

MIS18BP1

1001

Q6P0N0
LPDELLFADDSSEGS

MERTK

981

Q12866
EGSLLSDDFLDTPDD

ATCAY

76

Q86WG3
SDDFLDTPDDLDINV

ATCAY

81

Q86WG3
DGSSDLEIDELETPS

BNIPL

116

Q7Z465
SLPGGAESDSFLEDD

FSIP2

1716

Q5CZC0
EDDTADLFPEESGFE

ESF1

316

Q9H501
HDLDFAPDTELGSSE

LPO

226

P22079
LEDGDDFVSPALELS

NID1

46

P14543
KPLVALDTDSDDDFD

FAM219A

106

Q8IW50
LFDEPDSDSGLSLDS

NFE2L3

411

Q9Y4A8
LLDPDSVDDEFELST

KCNIP2

71

Q9NS61
LDFGGLSPSDSREEE

PSRC1

16

Q6PGN9
SSRDPLEDGDELLAD

PTF1A

31

Q7RTS3
FFLSEDSDDSPLLDD

DCHS2

101

Q6V1P9
ESIASLDDLDNDGFP

ITGA9

366

Q13797
GFTLGESPESEDDDS

ICE1

601

Q9Y2F5
FAEADDDDSLFPSIP

KCNA6

396

P17658
SLDSDSPLSDYGEEE

DNAAF8

36

Q8IYS4
ETEDESFPEAEDSLL

APPL2

476

Q8NEU8
TLDPSDGSVLSDDLD

BNIP2

61

Q12982
PSDLDQFSDSSLIED

LURAP1L

196

Q8IV03
SDESDSDLSDVPELD

EML5

616

Q05BV3
SEKLDSDDLLDNPGE

BICRA

26

Q9NZM4
EDGLDDSLLELSEGE

S100PBP

31

Q96BU1
DDSDLLQDLSPEEAS

CNST

571

Q6PJW8
ALDLLGSEDDDSAPE

PRIMPOL

196

Q96LW4
FSGDDSLLDLDPEDT

LAMA4

966

Q16363
LADPGSSDDDDVSSL

PHF20L1

876

A8MW92
SDGSDDLSESEPSEL

RTL1

581

A6NKG5
SSDDEFEDDLLDLNP

SOX4

396

Q06945
GPEDEDSSLDESDLY

NUPR1

16

O60356
SDTDSFEEDPEISLA

MDM2

286

Q00987
FLEEDTTDFPDELDT

RHBDF1

246

Q96CC6
DTSLDSDLDPEELAG

FTSJ3

466

Q8IY81
NPDSVLDTDGDFDLE

STAT5B

746

P51692
EETTDFGPLVLDSDS

PPP1R26

111

Q5T8A7
FGPLVLDSDSDDSVD

PPP1R26

116

Q5T8A7
GIFDLLDTGDDLDPD

MED13

1996

Q9UHV7
FDSAHPEEGDLDLAS

SAFB

261

Q15424
SLDDDLDGVPLDATE

U2SURP

731

O15042
DDWADLDDLDFSPSL

CILK1

416

Q9UPZ9
GALPDDFIDSLEKTD

NLN

221

Q9BYT8
SDLDTDAEGDDFELL

RETREG3

436

Q86VR2
AFESGLDLSDAEPDA

VEGFC

31

P49767
SDLNDPIILSSDDDD

SENP6

326

Q9GZR1
LPTSVSLFDDEDEED

WASHC2C

566

Q9Y4E1
LEPSVGSLFGDDEDD

WASHC2C

871

Q9Y4E1
LEPSVGSLFGDDEDD

WASHC2A

871

Q641Q2
LNDSDDDSPDLDLDG

PHF8

586

Q9UPP1
SGLPDKDSSFEDLEQ

VPS9D1

371

Q9Y2B5
EALSDGDDLRDFPSD

XPC

91

Q01831
LLPEGEDTFLSESDS

GTF3C1

466

Q12789
LPSTDSLDDFSDGDV

ZC3H7B

246

Q9UGR2
SLDDFSDGDVFGPEL

ZC3H7B

251

Q9UGR2
APGAFDDFLESLEDL

LRFN4

136

Q6PJG9