Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	triacylglycerol lipase activity	AADAC PLB1 LIPM	3.92e-05	26	51	3	GO:0004806
GeneOntologyCellularComponent	postsynaptic membrane	GABRG2 SCN8A LRP1 DMD UTRN GABRR3	4.89e-04	405	52	6	GO:0045211
GeneOntologyCellularComponent	cell projection membrane	GABRG2 PLB1 RDH11 SLC26A2 DMD UTRN	6.77e-04	431	52	6	GO:0031253
GeneOntologyCellularComponent	GABA-A receptor complex	GABRG2 GABRR3	1.01e-03	19	52	2	GO:1902711
GeneOntologyCellularComponent	dystrophin-associated glycoprotein complex	DMD UTRN	1.12e-03	20	52	2	GO:0016010
GeneOntologyCellularComponent	GABA receptor complex	GABRG2 GABRR3	1.24e-03	21	52	2	GO:1902710
GeneOntologyCellularComponent	filopodium membrane	DMD UTRN	1.24e-03	21	52	2	GO:0031527
Domain	Dystrophin	DMD UTRN	7.31e-06	2	51	2	IPR016344
Domain	EF-hand_dom_typ1	DMD UTRN	1.09e-04	6	51	2	IPR015153
Domain	EF-hand_dom_typ2	DMD UTRN	1.09e-04	6	51	2	IPR015154
Domain	EF-hand_2	DMD UTRN	1.09e-04	6	51	2	PF09068
Domain	EF-hand_3	DMD UTRN	1.09e-04	6	51	2	PF09069
Domain	ARM-type_fold	USP34 STK36 SF3B1 XPO5 LTN1 LYST	3.10e-04	339	51	6	IPR016024
Domain	ZF_ZZ_2	DMD UTRN	1.09e-03	18	51	2	PS50135
Domain	ZF_ZZ_1	DMD UTRN	1.09e-03	18	51	2	PS01357
Domain	ZZ	DMD UTRN	1.09e-03	18	51	2	PF00569
Domain	Znf_ZZ	DMD UTRN	1.21e-03	19	51	2	IPR000433
Domain	ZnF_ZZ	DMD UTRN	1.21e-03	19	51	2	SM00291
Domain	Actinin_actin-bd_CS	DMD UTRN	1.78e-03	23	51	2	IPR001589
Domain	ACTININ_2	DMD UTRN	1.78e-03	23	51	2	PS00020
Domain	ACTININ_1	DMD UTRN	1.78e-03	23	51	2	PS00019
Domain	GABAA/Glycine_rcpt	GABRG2 GABRR3	1.78e-03	23	51	2	IPR006028
Domain	Spectrin	DMD UTRN	1.78e-03	23	51	2	PF00435
Domain	Spectrin_repeat	DMD UTRN	2.83e-03	29	51	2	IPR002017
Domain	Spectrin/alpha-actinin	DMD UTRN	3.44e-03	32	51	2	IPR018159
Domain	SPEC	DMD UTRN	3.44e-03	32	51	2	SM00150
Domain	ARM-like	STK36 SF3B1 XPO5 LTN1	6.27e-03	270	51	4	IPR011989
Domain	Neurotransmitter_ion_chnl_CS	GABRG2 GABRR3	6.71e-03	45	51	2	IPR018000
Domain	Neur_chan_memb	GABRG2 GABRR3	7.01e-03	46	51	2	PF02932
Domain	Neur_chan_LBD	GABRG2 GABRR3	7.31e-03	47	51	2	PF02931
Domain	Neur_channel	GABRG2 GABRR3	7.31e-03	47	51	2	IPR006201
Domain	Neur_chan_lig-bd	GABRG2 GABRR3	7.31e-03	47	51	2	IPR006202
Domain	WW	DMD UTRN	7.31e-03	47	51	2	PF00397
Domain	NEUROTR_ION_CHANNEL	GABRG2 GABRR3	7.31e-03	47	51	2	PS00236
Domain	Neurotrans-gated_channel_TM	GABRG2 GABRR3	7.31e-03	47	51	2	IPR006029
Domain	-	GABRG2 GABRR3	7.31e-03	47	51	2	2.70.170.10
Domain	WW	DMD UTRN	7.61e-03	48	51	2	SM00456
Domain	HEAT	STK36 SF3B1	7.61e-03	48	51	2	PF02985
Domain	WW_DOMAIN_2	DMD UTRN	8.56e-03	51	51	2	PS50020
Domain	WW_DOMAIN_1	DMD UTRN	8.56e-03	51	51	2	PS01159
Domain	WW_dom	DMD UTRN	8.88e-03	52	51	2	IPR001202
Domain	FBOX	FBXL12 KDM2A	8.88e-03	52	51	2	SM00256
Domain	HEAT	STK36 SF3B1	1.10e-02	58	51	2	IPR000357
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	USP34 FAM234A SF3B1 NUP107 INTS2 RDH11 XPO5 WDR33 LRP1 SLFN5 STT3A RETREG3	1.59e-07	1203	52	12	29180619
Pubmed	Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy.	DMD UTRN	2.19e-06	2	52	2	10525423
Pubmed	Distribution of dystrophin- and utrophin-associated protein complexes during activation of human neutrophils.	DMD UTRN	2.19e-06	2	52	2	20434517
Pubmed	Plasma lipidomic analysis shows a disease progression signature in mdx mice.	DMD UTRN	2.19e-06	2	52	2	34155298
Pubmed	In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.	DMD UTRN	2.19e-06	2	52	2	28790199
Pubmed	Dystrophic changes in extraocular muscles after gamma irradiation in mdx:utrophin(+/-) mice.	DMD UTRN	2.19e-06	2	52	2	24466085
Pubmed	The Angiotensin Converting Enzyme Inhibitor Lisinopril Improves Muscle Histopathology but not Contractile Function in a Mouse Model of Duchenne Muscular Dystrophy.	DMD UTRN	2.19e-06	2	52	2	27110493
Pubmed	Rapid depletion of muscle progenitor cells in dystrophic mdx/utrophin-/- mice.	DMD UTRN	2.19e-06	2	52	2	24781208
Pubmed	Isolation and characterization of a genomic clone from the murine utrophin locus.	DMD UTRN	2.19e-06	2	52	2	8268660
Pubmed	Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.	DMD UTRN	2.19e-06	2	52	2	25859846
Pubmed	G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed in sensory ganglia and brain.	DMD UTRN	2.19e-06	2	52	2	7731967
Pubmed	Characterization of neuromuscular synapse function abnormalities in multiple Duchenne muscular dystrophy mouse models.	DMD UTRN	2.19e-06	2	52	2	27037492
Pubmed	Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue.	DMD UTRN	2.19e-06	2	52	2	16710609
Pubmed	Improvement in survival and muscle function in an mdx/utrn(-/-) double mutant mouse using a human retinal dystrophin transgene.	DMD UTRN	2.19e-06	2	52	2	16487708
Pubmed	Nonclinical Exon Skipping Studies with 2'-O-Methyl Phosphorothioate Antisense Oligonucleotides in mdx and mdx-utrn-/- Mice Inspired by Clinical Trial Results.	DMD UTRN	2.19e-06	2	52	2	30672725
Pubmed	Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart.	DMD UTRN	2.19e-06	2	52	2	21677768
Pubmed	Talin, vinculin and DRP (utrophin) concentrations are increased at mdx myotendinous junctions following onset of necrosis.	DMD UTRN	2.19e-06	2	52	2	7962191
Pubmed	Consequences of the combined deficiency in dystrophin and utrophin on the mechanical properties and myosin composition of some limb and respiratory muscles of the mouse.	DMD UTRN	2.19e-06	2	52	2	9713852
Pubmed	Skeletal muscle fibrosis in the mdx/utrn+/- mouse validates its suitability as a murine model of Duchenne muscular dystrophy.	DMD UTRN	2.19e-06	2	52	2	25607927
Pubmed	Does utrophin expression in muscles of mdx mice during postnatal development functionally compensate for dystrophin deficiency?	DMD UTRN	2.19e-06	2	52	2	8021701
Pubmed	Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.	DMD UTRN	2.19e-06	2	52	2	26974331
Pubmed	Developmental studies of dystrophin-positive fibers in mdx, and DRP localization.	DMD UTRN	2.19e-06	2	52	2	8433092
Pubmed	Second-generation compound for the modulation of utrophin in the therapy of DMD.	DMD UTRN	2.19e-06	2	52	2	25935002
Pubmed	Utrophin deficiency worsens cardiac contractile dysfunction present in dystrophin-deficient mdx mice.	DMD UTRN	2.19e-06	2	52	2	16024571
Pubmed	Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy.	DMD UTRN	2.19e-06	2	52	2	28453658
Pubmed	A quantitative study of bioenergetics in skeletal muscle lacking utrophin and dystrophin.	DMD UTRN	2.19e-06	2	52	2	11801396
Pubmed	Apo-dystrophin-1 and apo-dystrophin-2, products of the Duchenne muscular dystrophy locus: expression during mouse embryogenesis and in cultured cell lines.	DMD UTRN	2.19e-06	2	52	2	7987307
Pubmed	Utility of dystrophin and utrophin staining in childhood muscular dystrophy.	DMD UTRN	2.19e-06	2	52	2	16295426
Pubmed	Comparative analysis of the human dystrophin and utrophin gene structures.	DMD UTRN	2.19e-06	2	52	2	11861579
Pubmed	Distinct mechanical properties in homologous spectrin-like repeats of utrophin.	DMD UTRN	2.19e-06	2	52	2	30914715
Pubmed	Dystrophin is a microtubule-associated protein.	DMD UTRN	2.19e-06	2	52	2	19651889
Pubmed	Skeletal muscle-specific expression of a utrophin transgene rescues utrophin-dystrophin deficient mice.	DMD UTRN	2.19e-06	2	52	2	9590295
Pubmed	Comparison of skeletal muscle pathology and motor function of dystrophin and utrophin deficient mouse strains.	DMD UTRN	2.19e-06	2	52	2	22284942
Pubmed	Utrophin haploinsufficiency does not worsen the functional performance, resistance to eccentric contractions and force production of dystrophic mice.	DMD UTRN	2.19e-06	2	52	2	29879154
Pubmed	Haploinsufficiency of utrophin gene worsens skeletal muscle inflammation and fibrosis in mdx mice.	DMD UTRN	2.19e-06	2	52	2	17889902
Pubmed	Identification of Dp71 isoforms in the platelet membrane cytoskeleton. Potential role in thrombin-mediated platelet adhesion.	DMD UTRN	2.19e-06	2	52	2	12370193
Pubmed	Longitudinal metabolomic analysis of plasma enables modeling disease progression in Duchenne muscular dystrophy mouse models.	DMD UTRN	2.19e-06	2	52	2	32025735
Pubmed	Lifelong quercetin enrichment and cardioprotection in Mdx/Utrn+/- mice.	DMD UTRN	2.19e-06	2	52	2	27836895
Pubmed	BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle.	DMD UTRN	2.19e-06	2	52	2	27750047
Pubmed	NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model.	DMD IKBKB	2.19e-06	2	52	2	30143619
Pubmed	Prevention of dystrophin-deficient cardiomyopathy in twenty-one-month-old carrier mice by mosaic dystrophin expression or complementary dystrophin/utrophin expression.	DMD UTRN	2.19e-06	2	52	2	17967782
Pubmed	Diaphragm rescue alone prevents heart dysfunction in dystrophic mice.	DMD UTRN	2.19e-06	2	52	2	21062902
Pubmed	Matricellular Protein CCN5 Gene Transfer Ameliorates Cardiac and Skeletal Dysfunction in mdx/utrn (±) Haploinsufficient Mice by Reducing Fibrosis and Upregulating Utrophin Expression.	DMD UTRN	2.19e-06	2	52	2	35557546
Pubmed	Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice.	DMD UTRN	2.19e-06	2	52	2	37626761
Pubmed	Molecular heterogeneity of the dystrophin-associated protein complex in the mouse kidney nephron: differential alterations in the absence of utrophin and dystrophin.	DMD UTRN	2.19e-06	2	52	2	15565469
Pubmed	The N- and C-Terminal Domains Differentially Contribute to the Structure and Function of Dystrophin and Utrophin Tandem Calponin-Homology Domains.	DMD UTRN	2.19e-06	2	52	2	26516677
Pubmed	Assessment of cardiac function in three mouse dystrophinopathies by magnetic resonance imaging.	DMD UTRN	2.19e-06	2	52	2	22209498
Pubmed	A Protocol for Simultaneous In Vivo Imaging of Cardiac and Neuroinflammation in Dystrophin-Deficient MDX Mice Using [18F]FEPPA PET.	DMD UTRN	2.19e-06	2	52	2	37108685
Pubmed	Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.	DMD UTRN	2.19e-06	2	52	2	10694796
Pubmed	Dystrophin and dystrophin-related protein in the central nervous system of normal controls and Duchenne muscular dystrophy.	DMD UTRN	2.19e-06	2	52	2	8171962
Pubmed	Similar efficacy from specific and non-specific mineralocorticoid receptor antagonist treatment of muscular dystrophy mice.	DMD UTRN	2.19e-06	2	52	2	27822449
Pubmed	Micro-dystrophin gene therapy prevents heart failure in an improved Duchenne muscular dystrophy cardiomyopathy mouse model.	DMD UTRN	2.19e-06	2	52	2	33651713
Pubmed	Thermodynamic stability, unfolding kinetics, and aggregation of the N-terminal actin-binding domains of utrophin and dystrophin.	DMD UTRN	2.19e-06	2	52	2	22275054
Pubmed	NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation.	DMD UTRN	2.19e-06	2	52	2	27798264
Pubmed	Glycine administration attenuates progression of dystrophic pathology in prednisolone-treated dystrophin/utrophin null mice.	DMD UTRN	2.19e-06	2	52	2	31506484
Pubmed	Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy.	DMD UTRN	2.19e-06	2	52	2	9288752
Pubmed	Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy.	DMD UTRN	2.19e-06	2	52	2	9288751
Pubmed	Enhanced currents through L-type calcium channels in cardiomyocytes disturb the electrophysiology of the dystrophic heart.	DMD UTRN	2.19e-06	2	52	2	24337461
Pubmed	Combined gene therapy via VEGF and mini-dystrophin synergistically improves pathologies in temporalis muscle of dystrophin/utrophin double knockout mice.	DMD UTRN	2.19e-06	2	52	2	33987645
Pubmed	Activation of calcineurin and stress activated protein kinase/p38-mitogen activated protein kinase in hearts of utrophin-dystrophin knockout mice.	DMD UTRN	2.19e-06	2	52	2	11297940
Pubmed	Utrophin up-regulation by artificial transcription factors induces muscle rescue and impacts the neuromuscular junction in mdx mice.	DMD UTRN	2.19e-06	2	52	2	29408646
Pubmed	Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skipping.	DMD UTRN	2.19e-06	2	52	2	22388933
Pubmed	Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers.	DMD UTRN	2.19e-06	2	52	2	25642938
Pubmed	Activation of non-myogenic mesenchymal stem cells during the disease progression in dystrophic dystrophin/utrophin knockout mice.	DMD UTRN	2.19e-06	2	52	2	25859011
Pubmed	Satellite cells and utrophin are not directly correlated with the degree of skeletal muscle damage in mdx mice.	DMD UTRN	2.19e-06	2	52	2	15703201
Pubmed	Microtubule binding distinguishes dystrophin from utrophin.	DMD UTRN	2.19e-06	2	52	2	24706788
Pubmed	Utrophin suppresses low frequency oscillations and coupled gating of mechanosensitive ion channels in dystrophic skeletal muscle.	DMD UTRN	2.19e-06	2	52	2	25941878
Pubmed	Duchenne muscular dystrophy and the neuromuscular junction: the utrophin link.	DMD UTRN	2.19e-06	2	52	2	9297964
Pubmed	Dystrophin and utrophin do not play crucial roles in nonmuscle tissues in mice.	DMD UTRN	2.19e-06	2	52	2	10204788
Pubmed	SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models.	DMD UTRN	2.19e-06	2	52	2	25652448
Pubmed	Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis.	DMD UTRN	2.19e-06	2	52	2	28785010
Pubmed	The role of proteases in excitation-contraction coupling failure in muscular dystrophy.	DMD UTRN	2.19e-06	2	52	2	25298424
Pubmed	Restoration of all dystrophin protein interactions by functional domains in trans does not rescue dystrophy.	DMD UTRN	2.19e-06	2	52	2	16307000
Pubmed	Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice.	DMD UTRN	2.19e-06	2	52	2	21949353
Pubmed	Dystrophin and utrophin "double knockout" dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities.	DMD UTRN	2.19e-06	2	52	2	23097179
Pubmed	rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice.	DMD UTRN	2.19e-06	2	52	2	16819550
Pubmed	The role of utrophin and Dp71 for assembly of different dystrophin-associated protein complexes (DPCs) in the choroid plexus and microvasculature of the brain.	DMD UTRN	2.19e-06	2	52	2	15501597
Pubmed	Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice.	DMD UTRN	2.19e-06	2	52	2	11257121
Pubmed	Characterization of dystrophin and utrophin diversity in the mouse.	DMD UTRN	2.19e-06	2	52	2	10072426
Pubmed	The sparing of extraocular muscle in dystrophinopathy is lost in mice lacking utrophin and dystrophin.	DMD UTRN	2.19e-06	2	52	2	9625743
Pubmed	Systemic human minidystrophin gene transfer improves functions and life span of dystrophin and dystrophin/utrophin-deficient mice.	DMD UTRN	2.19e-06	2	52	2	18973234
Pubmed	Metabolic profiles of dystrophin and utrophin expression in mouse models of Duchenne muscular dystrophy.	DMD UTRN	2.19e-06	2	52	2	12387876
Pubmed	Renin-angiotensin-aldosterone system inhibitors improve membrane stability and change gene-expression profiles in dystrophic skeletal muscles.	DMD UTRN	2.19e-06	2	52	2	27881412
Pubmed	Dystrophins, utrophins, and associated scaffolding complexes: role in mammalian brain and implications for therapeutic strategies.	DMD UTRN	2.19e-06	2	52	2	20625423
Pubmed	Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle.	DMD UTRN	2.19e-06	2	52	2	29065908
Pubmed	Stabilization of the cardiac sarcolemma by sarcospan rescues DMD-associated cardiomyopathy.	DMD UTRN	2.19e-06	2	52	2	31039133
Pubmed	Developmentally regulated expression and localization of dystrophin and utrophin in the human fetal brain.	DMD UTRN	2.19e-06	2	52	2	11796130
Pubmed	Dystrophin and dystrophin-related protein in the brains of normal and mdx mice.	DMD UTRN	2.19e-06	2	52	2	8159184
Pubmed	Dystrophin and utrophin: genetic analyses of their role in skeletal muscle.	DMD UTRN	2.19e-06	2	52	2	10679963
Pubmed	TAT-μUtrophin mitigates the pathophysiology of dystrophin and utrophin double-knockout mice.	DMD UTRN	2.19e-06	2	52	2	21565990
Pubmed	Generation and characterization of transgenic mice with the full-length human DMD gene.	DMD UTRN	2.19e-06	2	52	2	18083704
Pubmed	Expression of the dystrophin-related protein (utrophin) gene during mouse embryogenesis.	DMD UTRN	2.19e-06	2	52	2	8130373
Pubmed	Early Inflammation in Muscular Dystrophy Differs between Limb and Respiratory Muscles and Increases with Dystrophic Severity.	DMD UTRN	2.19e-06	2	52	2	33497702
Pubmed	Dystrophin and dystrophin-related protein (utrophin) distribution in normal and dystrophin-deficient skeletal muscles.	DMD UTRN	2.19e-06	2	52	2	8186702
Pubmed	ANG1 treatment reduces muscle pathology and prevents a decline in perfusion in DMD mice.	DMD UTRN	2.19e-06	2	52	2	28334037
Pubmed	Contemporary cardiac issues in Duchenne muscular dystrophy. Working Group of the National Heart, Lung, and Blood Institute in collaboration with Parent Project Muscular Dystrophy.	DMD UTRN	2.19e-06	2	52	2	25940966
Pubmed	Cardiomyopathic features associated with muscular dystrophy are independent of dystrophin absence in cardiovasculature.	DMD UTRN	2.19e-06	2	52	2	12868498
Pubmed	Cardiac dysfunction and pathology in the dystrophin and utrophin-deficient mouse during development of dilated cardiomyopathy.	DMD UTRN	2.19e-06	2	52	2	22266080
Pubmed	Postnatal overexpression of the CT GalNAc transferase inhibits muscular dystrophy in mdx mice without altering muscle growth or neuromuscular development: evidence for a utrophin-independent mechanism.	DMD UTRN	2.19e-06	2	52	2	17300937
Pubmed	LINE-1 (L1) lineages in the mouse.	SCN8A LYST	2.19e-06	2	52	2	10742052
Cytoband	11q13.2	SYT12 KDM2A	1.37e-03	47	53	2	11q13.2
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	DMD UTRN	6.44e-04	18	38	2	91
GeneFamily	Gamma-aminobutyric acid type A receptor subunits	GABRG2 GABRR3	7.19e-04	19	38	2	563
GeneFamily	F-box and leucine rich repeat proteins	FBXL12 KDM2A	8.81e-04	21	38	2	558
GeneFamily	Lipases\|Arylacetamide deacetylase family	AADAC LIPM	9.68e-04	22	38	2	464
GeneFamily	Proteases, serine	PRSS35 PRSS45P	7.75e-03	63	38	2	738
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 SF3B1 KDM2A SLFN5 UTRN	3.98e-06	200	53	5	12f1685ce8f218433068e090c9d839cd5a1910bf
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	GABRG2 SCN8A	1.84e-04	12	50	2	DOID:0060170 (implicated_via_orthology)
Disease	muscular dystrophy (implicated_via_orthology)	DMD UTRN	5.79e-04	21	50	2	DOID:9884 (implicated_via_orthology)
Disease	Bilateral Wilms Tumor	XPO5 BCORL1	1.11e-03	29	50	2	C2930471
Disease	NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE	NUP107 XPO5	1.19e-03	30	50	2	C1868672

Protein segments in the cluster

Peptide	Gene	Start	Entry
DPHWESMLNATTRRM	FAM234A	306	Q9H0X4
NVEEPWRMMWINAHL	AADAC	26	P22760
MPWRTEAARQMWDTN	BCORL1	1301	Q5H9F3
MIMDDRLIANTLHWW	CMTR2	186	Q8IYT2
DHWRRSQMSMPFQQW	DNAJC12	76	Q9UKB3
FLDWMRLEPQSMVWL	DMD	3281	P11532
QTDAMDHRRWPAWKR	CBLL2	381	Q8N7E2
SARMKIPSNMWVEAW	RAB3GAP1	726	Q15042
ASMLWLLQQEMVTWR	NUP107	206	P57740
DSEWEKMRQSLPMQW	LTN1	951	O94822
MVPPEWHRWLHSMTD	NDUFA12	81	Q9UI09
WLQLMLMWHPRQRGT	IKBKB	276	O14920
SRQWIVSHRMEMWLL	LIPM	6	Q5VYY2
MTMRHNWTPDLSPLW	IL18BP	1	O95998
MAPTLATAHRRRWWM	SLC43A2	1	Q8N370
MFWTNWNEQHPSIMR	LRP1	2346	Q07954
LMVALTVRTWHWLMV	ATP9B	1056	O43861
MRQPLSWGRWRAMLA	NUDT6	1	P53370
LWMVLNTVMPRRLWV	INTS2	816	Q9H0H0
ILTFNISMHRSWWME	NKAIN2	96	Q5VXU1
MTEEVWMGTWRPHRP	ODF3	1	Q96PU9
MNESRWTEWRILNMS	GPR52	1	Q9Y2T5
MHMVRWAVWNPLLEA	NPHP4	386	O75161
VEQMWAPLWSRSMRP	CA5A	16	P35218
MVMLSWVSFWIDRRA	GABRR3	281	A8MPY1
IDWVDNMWPRHLKES	KDM2A	166	Q9Y2K7
LLVHRLSPLEMWTMW	B3GNT4	346	Q9C0J1
HDPRRQMFNWTHWSM	FRRS1	471	Q6ZNA5
HWITTPNRMLRIWND	GABRG2	161	P18507
MVRMSRPLFLDWAWR	LINC02898	1	Q6ZV80
HMHQAADIWSMCRWI	LYST	956	Q99698
TMTLEEGLWRAMREW	NUTM2D	301	Q5VT03
MTLEEGLWRAMREWQ	NUTM2G	251	Q5VZR2
WNQMLATLRRPVSMW	SYT12	401	Q8IV01
PALWIMAAKWEMEDR	UTP6	141	Q9NYH9
WMHLEPQSMVWLPVL	UTRN	3041	P46939
QSELVRHSSFMRWMW	RDH11	236	Q8TC12
MVIVRACPKESMDWW	FBXL12	311	Q9NXK8
WLRHNTPEDAKVMSW	STT3A	511	P46977
STTLAWHLWNRMMEP	PLB1	301	Q6P1J6
EMWTVLWHRFSMVLR	STK36	876	Q9NRP7
MMWPLAVYHRLWDRA	RETREG3	201	Q86VR2
MTRHWPWEVSLRMEN	PRSS45P	1	Q7RTY3
TMLTGNWRWALRVMP	SPNS3	196	Q6ZMD2
LPKMWSISRMDTVIW	SLC26A2	501	P50443
MSMTPEQLQAWRWER	SF3B1	376	O75533
LIWWMNHMASHPVLA	SNX18	356	Q96RF0
SEMEWDFMWHLRKVP	PRSS35	21	Q8N3Z0
VEMIKREWPQHWPDM	XPO5	121	Q9HAV4
RDPWNWLDFSVIMMA	SCN8A	191	Q9UQD0
FPIDSHTWERMWMHV	VASH2	56	Q86V25
VAMNGWMPARWDHQV	nan	161	Q8N9P0
WMPARWDHQVRRDVA	nan	166	Q8N9P0
FLDRMADDDWWPMQI	USP34	2346	Q70CQ2
EMAHEGMIWSLAWHP	WDR33	371	Q9C0J8
RQLPTREWTAWMMEA	SLFN5	321	Q08AF3
REWTAWMMEADPDLS	SLFN5	326	Q08AF3