Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	plus-end-directed microtubule motor activity	KIF1A KIF1B KIF1C	5.56e-05	17	89	3	GO:0008574
GeneOntologyBiologicalProcess	retrograde neuronal dense core vesicle transport	KIF1A KIF1B KIF1C	1.44e-06	6	87	3	GO:1990049
GeneOntologyBiologicalProcess	anterograde neuronal dense core vesicle transport	KIF1A KIF1B KIF1C	4.00e-06	8	87	3	GO:1990048
GeneOntologyBiologicalProcess	dense core granule cytoskeletal transport	KIF1A KIF1B KIF1C	1.55e-05	12	87	3	GO:0099519
GeneOntologyBiologicalProcess	dense core granule transport	KIF1A KIF1B KIF1C	2.55e-05	14	87	3	GO:1901950
GeneOntologyBiologicalProcess	complement activation, classical pathway	C1S C7 CR2 SVEP1	3.52e-05	44	87	4	GO:0006958
GeneOntologyBiologicalProcess	farnesyl diphosphate biosynthetic process	FDPS HMGCS2	1.05e-04	4	87	2	GO:0045337
GeneOntologyBiologicalProcess	humoral immune response mediated by circulating immunoglobulin	C1S C7 CR2 SVEP1	1.37e-04	62	87	4	GO:0002455
GeneOntologyBiologicalProcess	retrograde axonal transport	KIF1A KIF1B KIF1C	1.38e-04	24	87	3	GO:0008090
GeneOntologyBiologicalProcess	complement activation	C1S C7 CR2 SVEP1	2.19e-04	70	87	4	GO:0006956
GeneOntologyBiologicalProcess	dense core granule localization	KIF1A KIF1B KIF1C	2.20e-04	28	87	3	GO:0032253
GeneOntologyCellularComponent	Cul3-RING ubiquitin ligase complex	KLHL24 KLHL25 KLHL13 ENC1	2.25e-05	39	89	4	GO:0031463
Domain	Gal_Oxase/kelch_b-propeller	KLHL24 KLHL10 KLHL25 KLHL13 ENC1 KLHDC4	3.63e-07	59	89	6	IPR011043
Domain	Kelch_1	KLHL24 KLHL10 KLHL25 KLHL13 ENC1 KLHDC4	1.01e-06	70	89	6	PF01344
Domain	Kelch_1	KLHL24 KLHL10 KLHL25 KLHL13 ENC1 KLHDC4	1.01e-06	70	89	6	IPR006652
Domain	BTB-kelch_protein	KLHL24 KLHL10 KLHL25 KLHL13 ENC1	1.83e-06	43	89	5	IPR017096
Domain	Kinesin_assoc	KIF1A KIF1B KIF1C	2.07e-06	6	89	3	PF16183
Domain	Kinesin_assoc	KIF1A KIF1B KIF1C	2.07e-06	6	89	3	IPR032405
Domain	Sushi	PAPPA2 C1S C7 CR2 SVEP1	4.78e-06	52	89	5	PF00084
Domain	CCP	PAPPA2 C1S C7 CR2 SVEP1	5.77e-06	54	89	5	SM00032
Domain	SUSHI	PAPPA2 C1S C7 CR2 SVEP1	6.92e-06	56	89	5	PS50923
Domain	Sushi_SCR_CCP_dom	PAPPA2 C1S C7 CR2 SVEP1	7.56e-06	57	89	5	IPR000436
Domain	Kelch	KLHL24 KLHL10 KLHL25 KLHL13 ENC1	8.24e-06	58	89	5	SM00612
Domain	BACK	KLHL24 KLHL10 KLHL25 KLHL13 ENC1	9.74e-06	60	89	5	SM00875
Domain	BACK	KLHL24 KLHL10 KLHL25 KLHL13 ENC1	1.06e-05	61	89	5	IPR011705
Domain	BACK	KLHL24 KLHL10 KLHL25 KLHL13 ENC1	1.06e-05	61	89	5	PF07707
Domain	Filamin	TRIM45 FLNB MYCBP2	1.68e-05	11	89	3	PF00630
Domain	FILAMIN_REPEAT	TRIM45 FLNB MYCBP2	1.68e-05	11	89	3	PS50194
Domain	Filamin/ABP280_rpt	TRIM45 FLNB MYCBP2	1.68e-05	11	89	3	IPR001298
Domain	Filamin/ABP280_repeat-like	TRIM45 FLNB MYCBP2	1.68e-05	11	89	3	IPR017868
Domain	TMEM131-like	TMEM131L TMEM131	2.25e-05	2	89	2	IPR022113
Domain	TMEM131_like	TMEM131L TMEM131	2.25e-05	2	89	2	PF12371
Domain	Kinesin-like_KIF1-typ	KIF1A KIF1B	1.34e-04	4	89	2	IPR022140
Domain	KIF1B	KIF1A KIF1B	1.34e-04	4	89	2	PF12423
Domain	-	KLHL24 KLHL10 KLHL13	2.82e-04	27	89	3	2.130.10.80
Domain	FHA	KIF1A KIF1B KIF1C	3.14e-04	28	89	3	SM00240
Domain	Kinesin-like	KIF1A KIF1B	3.33e-04	6	89	2	IPR022164
Domain	DUF3694	KIF1A KIF1B	3.33e-04	6	89	2	PF12473
Domain	BTB	KLHL24 KLHL10 KLHL25 KLHL13 ENC1	4.07e-04	131	89	5	PF00651
Domain	FHA_DOMAIN	KIF1A KIF1B KIF1C	4.27e-04	31	89	3	PS50006
Domain	FHA	KIF1A KIF1B KIF1C	4.27e-04	31	89	3	PF00498
Domain	Gal_Oxidase_b-propeller	KLHL24 KLHL10 KLHL13	5.62e-04	34	89	3	IPR015916
Domain	PIPKc	PIKFYVE PIP5K1C	6.17e-04	8	89	2	SM00330
Domain	-	PIKFYVE PIP5K1C	6.17e-04	8	89	2	3.30.800.10
Domain	PIP5K	PIKFYVE PIP5K1C	6.17e-04	8	89	2	PF01504
Domain	PIPK	PIKFYVE PIP5K1C	6.17e-04	8	89	2	PS51455
Domain	PInositol-4-P-5-kinase_N	PIKFYVE PIP5K1C	6.17e-04	8	89	2	IPR027484
Domain	PInositol-4-P-5-kinase_C	PIKFYVE PIP5K1C	6.17e-04	8	89	2	IPR027483
Domain	-	PIKFYVE PIP5K1C	6.17e-04	8	89	2	3.30.810.10
Domain	PInositol-4-P-5-kinase_core	PIKFYVE PIP5K1C	6.17e-04	8	89	2	IPR002498
Domain	-	KIF1A KIF1B KIF1C	6.67e-04	36	89	3	2.60.200.20
Domain	FHA_dom	KIF1A KIF1B KIF1C	6.67e-04	36	89	3	IPR000253
Domain	Calx_beta	ADGRV1 FREM1	7.91e-04	9	89	2	IPR003644
Domain	Calx-beta	ADGRV1 FREM1	7.91e-04	9	89	2	PF03160
Domain	EGF_3	STAB2 UMODL1 C1S C7 SSPOP SVEP1	9.06e-04	235	89	6	PS50026
Domain	LDLR_class-A_CS	SPINT1 C7 SSPOP	9.10e-04	40	89	3	IPR023415
Domain	Kinesin_motor_CS	KIF1A KIF1B KIF1C	9.78e-04	41	89	3	IPR019821
Domain	IG_FLMN	TRIM45 FLNB	9.86e-04	10	89	2	SM00557
Domain	BTB	KLHL24 KLHL10 KLHL25 KLHL13 ENC1	1.01e-03	160	89	5	PS50097
Domain	Kinesin-like_fam	KIF1A KIF1B KIF1C	1.12e-03	43	89	3	IPR027640
Domain	GFP-like	STAB2 SVEP1	1.20e-03	11	89	2	IPR023413
Domain	-	STAB2 SVEP1	1.20e-03	11	89	2	2.40.155.10
Domain	-	KIF1A KIF1B KIF1C	1.20e-03	44	89	3	3.40.850.10
Domain	Kinesin	KIF1A KIF1B KIF1C	1.20e-03	44	89	3	PF00225
Domain	KISc	KIF1A KIF1B KIF1C	1.20e-03	44	89	3	SM00129
Domain	KINESIN_MOTOR_1	KIF1A KIF1B KIF1C	1.20e-03	44	89	3	PS00411
Domain	Kinesin_motor_dom	KIF1A KIF1B KIF1C	1.20e-03	44	89	3	IPR001752
Domain	KINESIN_MOTOR_2	KIF1A KIF1B KIF1C	1.20e-03	44	89	3	PS50067
Domain	-	PAPPA2 TRIM45 FLNB MYCBP2 UMODL1 CD79A MDGA2 RIMBP2 IGSF1 MDGA1	1.21e-03	663	89	10	2.60.40.10
Domain	EGF-like_dom	STAB2 UMODL1 PCSK6 C1S C7 SVEP1	1.22e-03	249	89	6	IPR000742
Domain	Ldl_recept_a	SPINT1 C7 SSPOP	1.28e-03	45	89	3	PF00057
Domain	-	SPINT1 C7 SSPOP	1.37e-03	46	89	3	4.10.400.10
Domain	EGF_1	STAB2 UMODL1 C1S C7 SSPOP SVEP1	1.38e-03	255	89	6	PS00022
Domain	Ig_E-set	TRIM45 FLNB MYCBP2 NXPE3	1.54e-03	104	89	4	IPR014756
Domain	LDLRA_1	SPINT1 C7 SSPOP	1.55e-03	48	89	3	PS01209
Domain	-	KLHL25 ENC1 KLHDC4	1.55e-03	48	89	3	2.120.10.80
Domain	LDrepeatLR_classA_rpt	SPINT1 C7 SSPOP	1.64e-03	49	89	3	IPR002172
Domain	LDLa	SPINT1 C7 SSPOP	1.64e-03	49	89	3	SM00192
Domain	LDLRA_2	SPINT1 C7 SSPOP	1.64e-03	49	89	3	PS50068
Domain	EGF_2	STAB2 UMODL1 C1S C7 SSPOP SVEP1	1.68e-03	265	89	6	PS01186
Domain	BTB	KLHL24 KLHL10 KLHL25 KLHL13 ENC1	1.70e-03	180	89	5	SM00225
Domain	BTB/POZ_dom	KLHL24 KLHL10 KLHL25 KLHL13 ENC1	1.92e-03	185	89	5	IPR000210
Domain	Ig-like_fold	PAPPA2 TRIM45 FLNB MYCBP2 UMODL1 CD79A MDGA2 RIMBP2 IGSF1 MDGA1	1.93e-03	706	89	10	IPR013783
Domain	SMAD_FHA_domain	KIF1A KIF1B KIF1C	1.95e-03	52	89	3	IPR008984
Domain	PLAC	PCSK6 ADAMTSL2	1.97e-03	14	89	2	PF08686
Domain	SKP1/BTB/POZ	KLHL24 KLHL10 KLHL25 KLHL13 ENC1	2.10e-03	189	89	5	IPR011333
Domain	Kelch-typ_b-propeller	KLHL25 ENC1 KLHDC4	2.29e-03	55	89	3	IPR015915
Domain	MAM_1	MDGA2 MDGA1	2.58e-03	16	89	2	PS00740
Domain	EGF_CA	STAB2 UMODL1 C1S SVEP1	2.76e-03	122	89	4	SM00179
Domain	Poly(ADP-ribose)pol_cat_dom	TNKS PARP14	2.91e-03	17	89	2	IPR012317
Domain	PARP_CATALYTIC	TNKS PARP14	2.91e-03	17	89	2	PS51059
Domain	PARP	TNKS PARP14	2.91e-03	17	89	2	PF00644
Domain	EMI	UMODL1 SSPOP	2.91e-03	17	89	2	PS51041
Domain	-	TNKS PARP14	2.91e-03	17	89	2	3.90.228.10
Domain	MAM	MDGA2 MDGA1	2.91e-03	17	89	2	SM00137
Domain	EGF-like_Ca-bd_dom	STAB2 UMODL1 C1S SVEP1	2.93e-03	124	89	4	IPR001881
Domain	FN3_dom	PAPPA2 UMODL1 MDGA2 RIMBP2 MDGA1	3.24e-03	209	89	5	IPR003961
Domain	MAM	MDGA2 MDGA1	3.27e-03	18	89	2	PF00629
Domain	MAM_dom	MDGA2 MDGA1	3.27e-03	18	89	2	IPR000998
Domain	MAM_2	MDGA2 MDGA1	3.27e-03	18	89	2	PS50060
Domain	TSP_1	C7 SSPOP ADAMTSL2	3.38e-03	63	89	3	PF00090
Domain	PLAC	PCSK6 ADAMTSL2	3.64e-03	19	89	2	PS50900
Domain	PLAC	PCSK6 ADAMTSL2	3.64e-03	19	89	2	IPR010909
Domain	TSP1	C7 SSPOP ADAMTSL2	3.69e-03	65	89	3	SM00209
Domain	TSP1_rpt	C7 SSPOP ADAMTSL2	3.69e-03	65	89	3	IPR000884
Domain	TSP1	C7 SSPOP ADAMTSL2	3.69e-03	65	89	3	PS50092
Domain	ConA-like_dom	PAPPA2 MDGA2 ADGRV1 MDGA1 SVEP1	3.96e-03	219	89	5	IPR013320
Pubmed	In vivo optical trapping indicates kinesin's stall force is reduced by dynein during intracellular transport.	KIF1A KIF1B KIF1C	1.68e-08	3	90	3	23404705
Pubmed	Update on the Kelch-like (KLHL) gene family.	KLHL24 KLHL10 KLHL25 KLHL13 ENC1	7.22e-08	41	90	5	23676014
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZNF512B SF3B3 PDPR FDPS TMEM131L ADGRV1 IGSF1 KDM6B ADNP MED13 CEMIP2	1.28e-07	529	90	11	14621295
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ZNF512B FLNB KIF1A MYCBP2 ZNF92 PCSK6 KIF1B ENC1 C1S TMEM131 TNKS KDM6B RFX5 MED13 AFF4 DNMT1	1.80e-07	1285	90	16	35914814
Pubmed	HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus.	KIF1A KIF1B KIF1C	9.30e-07	8	90	3	25818806
Pubmed	Complement component C7 is a plasminogen-binding protein.	C7 PLG	6.62e-06	2	90	2	7814888
Pubmed	The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors.	KIF1A KIF1B	6.62e-06	2	90	2	7539720
Pubmed	Survival of resting mature B lymphocytes depends on BCR signaling via the Igalpha/beta heterodimer.	CD79A CR2	6.62e-06	2	90	2	15186779
Pubmed	Tyrosine phosphorylation of MB-1, B29, and HS1 proteins in human B cells following receptor crosslinking.	CD79A HCLS1	6.62e-06	2	90	2	7927516
Pubmed	Identification and characterization of two novel brain-derived immunoglobulin superfamily members with a unique structural organization.	MDGA2 MDGA1	6.62e-06	2	90	2	15019943
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	KIF1B PIP5K1C SSPOP MED13 ADAMTSL2	8.17e-06	105	90	5	9628581
Pubmed	Visualization of splenic marginal zone B-cell shuttling and follicular B-cell egress.	CD79A CR2	1.98e-05	3	90	2	23263181
Pubmed	BORC Functions Upstream of Kinesins 1 and 3 to Coordinate Regional Movement of Lysosomes along Different Microtubule Tracks.	KIF1A KIF1B	1.98e-05	3	90	2	27851960
Pubmed	A novel missense variant in CUL3 shows altered binding ability to BTB-adaptor proteins leading to diverse phenotypes of CUL3-related disorders.	KLHL24 KLHL25 KLHL13	2.86e-05	23	90	3	33130828
Pubmed	Dimerization quality control ensures neuronal development and survival.	KLHL24 KLHL13 ENC1	3.26e-05	24	90	3	30190310
Pubmed	Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.	KIF1A KIF1B KIF1C	3.70e-05	25	90	3	9275178
Pubmed	The Molecular Motor KIF1A Transports the TrkA Neurotrophin Receptor and Is Essential for Sensory Neuron Survival and Function.	KIF1A KIF1B	3.96e-05	4	90	2	27263974
Pubmed	Loss of H3K36 Methyltransferase SETD2 Impairs V(D)J Recombination during Lymphoid Development.	SETD2 CD79A	6.59e-05	5	90	2	32169821
Pubmed	KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD.	KIF1A KIF1B	6.59e-05	5	90	2	18849981
Pubmed	IκB kinase ε-dependent phosphorylation and degradation of X-linked inhibitor of apoptosis sensitizes cells to virus-induced apoptosis.	IKBKE XIAP	6.59e-05	5	90	2	22072751
Pubmed	Interaction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse development.	MDGA2 MDGA1	6.59e-05	5	90	2	23358245
Pubmed	Association study of cholesterol-related genes in Alzheimer's disease.	FDPS HMGCS2	6.59e-05	5	90	2	17387528
Pubmed	Characterization of the cDNA coding for mouse plasminogen and localization of the gene to mouse chromosome 17.	PLG MAP3K4	6.59e-05	5	90	2	2081600
Pubmed	Testing gene function early in the B cell lineage in mb1-cre mice.	CD79A DNMT1	6.59e-05	5	90	2	16940357
Pubmed	Detailed physical and genetic mapping in the region of plasminogen, D17Rp17e, and quaking.	PLG MAP3K4	6.59e-05	5	90	2	8111116
Pubmed	Genetic analysis of cholesterol accumulation in inbred mice.	FDPS HMGCS2	6.59e-05	5	90	2	11714850
Pubmed	Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.	C1S C7 CR2	7.15e-05	31	90	3	19344414
Pubmed	Insights into the ubiquitin-proteasome system of human embryonic stem cells.	RPL30 SF3B3 PDHA1 DDX42 KLHDC4 DNMT1	7.32e-05	269	90	6	29511261
Pubmed	Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.	C7 CR2 RFX5	7.87e-05	32	90	3	18842294
Pubmed	A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.	KLHL24 KLHL25 KLHL13 ENC1	7.92e-05	87	90	4	37495603
Pubmed	Mapping a gene for combined hyperlipidaemia in a mutant mouse strain.	FDPS HMGCS2	9.87e-05	6	90	2	9537422
Pubmed	The virulence function of Streptococcus pneumoniae surface protein A involves inhibition of complement activation and impairment of complement receptor-mediated protection.	CR2 ITGAX	9.87e-05	6	90	2	15585877
Pubmed	Murine subtilisin-like proteinase SPC6 is expressed during embryonic implantation, somitogenesis, and skeletal formation.	TIMP3 PCSK6	9.87e-05	6	90	2	9291583
Pubmed	Tumor suppressor menin represses paired box gene 2 expression via Wilms tumor suppressor protein-polycomb group complex.	KDM6B DNMT1	9.87e-05	6	90	2	21378168
Pubmed	Rac controls PIP5K localisation and PtdIns(4,5)P₂ synthesis, which modulates vinculin localisation and neurite dynamics.	PIKFYVE PIP5K1C	9.87e-05	6	90	2	20841379
Pubmed	The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases.	TIMP3 PCSK6	9.87e-05	6	90	2	16135528
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	PIKFYVE SETD2 MYCBP2 DDX42 TMEM131L TMEM131 TMEM38B CEMIP2 DNMT1	1.21e-04	733	90	9	34672954
Pubmed	All kinesin superfamily protein, KIF, genes in mouse and human.	KIF1A KIF1B KIF1C	1.22e-04	37	90	3	11416179
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	ZNF512B PIKFYVE SLC25A24 RPL30 GK PDPR MYCBP2 PDHA1 NUP37 XIAP TMEM131 TMEM38B WDR44	1.23e-04	1496	90	13	32877691
Pubmed	Localization of mRNAs for phosphatidylinositol phosphate kinases in the mouse brain during development.	PIKFYVE PIP5K1C	1.38e-04	7	90	2	15018809
Pubmed	MEKK4 signaling regulates filamin expression and neuronal migration.	FLNB MAP3K4	1.84e-04	8	90	2	17145501
Pubmed	CD11c+ T-bet+ B Cells Require IL-21 and IFN-γ from Type 1 T Follicular Helper Cells and Intrinsic Bcl-6 Expression but Develop Normally in the Absence of T-bet.	CD79A ITGAX	1.84e-04	8	90	2	32680956
Pubmed	The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus.	PLG MAP3K4	1.84e-04	8	90	2	1845916
Pubmed	Btk-dependent regulation of phosphoinositide synthesis.	PIKFYVE PIP5K1C	1.84e-04	8	90	2	15046600
Pubmed	Antimitotic effect of the retinoid 4-oxo-fenretinide through inhibition of tubulin polymerization: a novel mechanism of retinoid growth-inhibitory activity.	TNKS KIF1C	1.84e-04	8	90	2	19996280
Pubmed	Yeast two-hybrid screening identified WDR77 as a novel interacting partner of TSC22D2.	FLNB ATP1B1 MED13	2.20e-04	45	90	3	27337956
Pubmed	ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway.	FLNB MAP3K4	2.36e-04	9	90	2	19270716
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RPL30 FLNB KIF1A MYCBP2 PDHA1 DDX42 ADNP DNMT1	2.97e-04	653	90	8	22586326
Pubmed	Characterization of the C3 YAC contig from proximal mouse chromosome 17 and analysis of allelic expression of genes flanking the imprinted Igf2r gene.	PLG MAP3K4	3.59e-04	11	90	2	9268631
Pubmed	Genetic variants in eleven telomere-associated genes and the risk of incident cardio/cerebrovascular disease: The Women's Genome Health Study.	UCP2 TNKS	3.59e-04	11	90	2	20937264
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	KLHL10 SF3B3 KLHL25 IKBKE KLHL13 ENC1	4.21e-04	372	90	6	22939624
Pubmed	Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1.	KIF1A KIF1B	4.30e-04	12	90	2	16301330
Pubmed	Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs.	PDPR PDHA1	4.30e-04	12	90	2	12676647
Pubmed	Novel CUL3 Variant Causing Familial Hyperkalemic Hypertension Impairs Regulation and Function of Ubiquitin Ligase Activity.	KLHL24 KLHL25 KLHL13	4.43e-04	57	90	3	34878901
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FLNB KIF1A SH3TC1 MYCBP2 UCKL1 KIF1B ENC1 XIAP PLCB4 ADGRV1 SSPOP AFF4	4.53e-04	1489	90	12	28611215
Pubmed	The role of TBK1 and IKKε in the expression and activation of Pellino 1.	IKBKE IRAK4	5.07e-04	13	90	2	21204785
Pubmed	Extra-embryonic-specific imprinted expression is restricted to defined lineages in the post-implantation embryo.	PLG DNMT1	5.07e-04	13	90	2	21354127
Pubmed	Linkage and association of successful aging to the 6q25 region in large Amish kindreds.	PLG MAP3K4	5.07e-04	13	90	2	22773346
Pubmed	Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.	ADGRV1 MYO15A	5.91e-04	14	90	2	26754646
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ACSL6 KLHL13 KIF1B RIMBP2 PIP5K1C MAP3K4	6.74e-04	407	90	6	12693553
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	ZNF512B DDX42 RFX5 MED13 AFF4	6.75e-04	268	90	5	33640491
Pubmed	Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.	MDGA1 SSPOP	6.80e-04	15	90	2	20473291
Pubmed	FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation.	MYCBP2 MED13	6.80e-04	15	90	2	31285543
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ZNF512B RPL30 SETD2 DDX42 XIAP ADNP AFF4 WDR44 DNMT1	7.08e-04	934	90	9	33916271
Pubmed	Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects.	ACSL6 UCP2 CR2	7.12e-04	67	90	3	16806233
Pubmed	Identification of 40 genes on a 1-Mb contig around the IL-4 cytokine family gene cluster on mouse chromosome 11.	ACSL6 AFF4	7.76e-04	16	90	2	10704283
Pubmed	High-throughput RNAi screening reveals novel regulators of telomerase.	TNKS MAP3K4	7.76e-04	16	90	2	21531765
Pubmed	Family-wide analysis of poly(ADP-ribose) polymerase activity.	TNKS PARP14	7.76e-04	16	90	2	25043379
Pubmed	High-resolution comparative mapping of mouse chromosome 17.	PLG MAP3K4	7.76e-04	16	90	2	8406442
Pubmed	USP25 regulates Wnt signaling by controlling the stability of tankyrases.	KLHL13 TNKS	7.76e-04	16	90	2	28619731
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	ZNF512B RPL30 SETD2 SF3B3 DDX42 ADNP RFX5 AFF4 DNMT1	8.22e-04	954	90	9	36373674
Pubmed	TNFα-dependent development of lymphoid tissue in the absence of RORγt⁺ lymphoid tissue inducer cells.	CR2 ITGAX	8.78e-04	17	90	2	24129162
Pubmed	Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding.	ZNF512B RPL30 ADNP	8.78e-04	72	90	3	31248990
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SETD2 MYCBP2 PDHA1 KIF1B KLHDC4 MED13 WDR44 DNMT1	9.04e-04	774	90	8	15302935
Pubmed	The RNA ligase RNA terminal phosphate cyclase B regulates mRNA alternative splicing and is required for mouse oocyte development and maintenance.	TDRD9 DNMT1	9.86e-04	18	90	2	36178098
Pubmed	The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.	TIMP3 ATP1B1 TMEM38B CEMIP2	1.15e-03	176	90	4	28692057
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	FLNB KLHL24 MYCBP2 PDHA1 KLHL13 XIAP RIMBP2 TNKS DNMT1	1.18e-03	1005	90	9	19615732
Pubmed	The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline.	TDRD9 DNMT1	1.22e-03	20	90	2	20059948
Pubmed	Histone H3 lysine 36 methyltransferase Hypb/Setd2 is required for embryonic vascular remodeling.	SETD2 PLG	1.22e-03	20	90	2	20133625
Pubmed	High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.	ACSL6 SPINT1 MYCBP2 DDX42 CR2	1.24e-03	307	90	5	37499664
Pubmed	USP15 Deubiquitinates TUT1 Associated with RNA Metabolism and Maintains Cerebellar Homeostasis.	MYCBP2 XIAP	1.35e-03	21	90	2	32839293
Pubmed	In silico QTL mapping of basal liver iron levels in inbred mouse strains.	PLG MAP3K4	1.35e-03	21	90	2	21062905
Pubmed	Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly.	SF3B3 DDX42	1.35e-03	21	90	2	36797247
Pubmed	Altered gene expression pattern in the fatty liver dystrophy mouse reveals impaired insulin-mediated cytoskeleton dynamics.	FDPS HMGCS2	1.48e-03	22	90	2	10438476
Pubmed	Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala.	SPINT1 PCSK6 ENC1	1.57e-03	88	90	3	21491433
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ZNF512B RPL30 SF3B3 PDPR MYCBP2 PDHA1 DDX42 TMEM131L TMEM131 CEMIP2 DNMT1	1.58e-03	1487	90	11	33957083
Pubmed	Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays.	KIF1B SCN4A	1.62e-03	23	90	2	16637659
Pubmed	Antibodies and complement are key drivers of thrombosis.	CR2 ITGAX	1.62e-03	23	90	2	39226900
Pubmed	Functional genetic analysis of mouse chromosome 11.	MED13 FREM1	1.62e-03	23	90	2	12955145
Pubmed	Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.	PDPR PDHA1 PGM3	1.84e-03	93	90	3	27215380
Pubmed	Capillary endothelial fatty acid binding proteins 4 and 5 play a critical role in fatty acid uptake in heart and skeletal muscle.	PDHA1 UCP2	1.91e-03	25	90	2	23968980
Pubmed	CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs.	PDHA1 HMGCS2	1.91e-03	25	90	2	28188211
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	FDPS DDX42 PARP14 ADNP AFF4	1.96e-03	341	90	5	32971831
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	ZNF512B SLC25A24 SETD2 SF3B3 MYCBP2 DDX42 IRAK4 ADNP AFF4	1.96e-03	1082	90	9	38697112
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	FLNB TIMP3 ENC1 DDX42 IRAK4 TMEM131L XIAP TMEM131 AFF4	1.98e-03	1084	90	9	11544199
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	RPL30 FLNB UCKL1 TMEM131 WDR44 KIF1C	1.99e-03	503	90	6	16964243
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	PIKFYVE KIF1A TMEM131L TMEM131 TMEM38B CEMIP2	2.01e-03	504	90	6	34432599
Pubmed	ATRX promotes heterochromatin formation to protect cells from G-quadruplex DNA-mediated stress.	SETD2 ADNP	2.07e-03	26	90	2	34162889
Pubmed	DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors.	MDGA2 MDGA1	2.07e-03	26	90	2	34848499
Pubmed	Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.	PAPPA2 TIMP3 C7	2.13e-03	98	90	3	19834535
Cytoband	Ensembl 112 genes in cytogenetic band chr6q26	PLG MAP3K4	4.48e-04	16	90	2	chr6q26
Cytoband	6q26	PLG MAP3K4	5.70e-04	18	90	2	6q26
Cytoband	5q13	ENC1 ADGRV1	8.56e-04	22	90	2	5q13
GeneFamily	Kelch like\|BTB domain containing	KLHL24 KLHL10 KLHL25 KLHL13 ENC1	2.86e-07	42	61	5	617
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	PAPPA2 C1S C7 CR2 SVEP1	1.35e-06	57	61	5	1179
GeneFamily	Complement system\|Sushi domain containing	C1S C7 CR2 ITGAX	6.37e-06	36	61	4	492
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KLHL24 KLHL10 KLHL25 KLHL13 ENC1	8.85e-05	134	61	5	861
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF1A KIF1B KIF1C	5.00e-04	46	61	3	622
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	TNKS PARP14	1.47e-03	17	61	2	684
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	PIKFYVE SLC25A24 FLNB SETD2 MYCBP2 ENC1 DDX42 TMEM131L TMEM131 TNKS PLCB4 ADNP MED13 MAP3K4	1.28e-06	856	90	14	M4500
Coexpression	GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_DN	FLNB SF3B3 FDPS KIF1B CD79A HCLS1 MAP3K4	5.93e-06	200	90	7	M5101
Coexpression	GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_BCELL_DN	PIKFYVE SLC25A24 PDHA1 FDPS UCKL1 RFX5 DNMT1	5.93e-06	200	90	7	M6745
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MELTF STAB2 MDGA2 ADGRV1 MYO15A SSPOP FREM1	9.58e-08	184	90	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MELTF STAB2 MDGA2 ADGRV1 MYO15A SSPOP FREM1	9.58e-08	184	90	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MELTF STAB2 MDGA2 ADGRV1 MYO15A SSPOP FREM1	9.58e-08	184	90	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIKFYVE RPL30 MYCBP2 CD79A KDM6B PARP14 CR2	1.03e-07	186	90	7	1a1e5d85a5ad90afee234c12a9b54a5e93a8a2f2
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIKFYVE RPL30 MYCBP2 CD79A KDM6B PARP14 CR2	1.03e-07	186	90	7	f1366638edaecad5cad6367440f4c693513bed7e
ToppCell	CF-Lymphoid-B_cell\|Lymphoid / Disease state, Lineage and Cell class	PIKFYVE MYCBP2 TMEM131L CD79A TMEM131 PARP14 ITGAX	1.33e-07	193	90	7	7ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TIMP3 ENC1 C1S CD79A SVEP1 FREM1 ADAMTSL2	1.52e-07	197	90	7	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	Biopsy_IPF-Mesenchymal-Fibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	PAPPA2 TIMP3 C1S C7 SVEP1 FREM1 ADAMTSL2	1.69e-07	200	90	7	d8637f1e62d3fb9476dc51e1b1dc2f4b14b5fcd8
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX6 C1S RIMBP2 ADGRV1 SVEP1 FREM1	8.96e-07	160	90	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX6 C1S RIMBP2 ADGRV1 SVEP1 FREM1	8.96e-07	160	90	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Multiple_Sclerosis-Other-HSPC\|Multiple_Sclerosis / Disease, Lineage and Cell Type	TIMP3 KLHL13 RIMBP2 PLCB4 ATP1B1 FREM1	1.03e-06	164	90	6	6af5529507d695b347adee4be5ead70f56c9cf55
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FDPS ENTPD5 C1S HMGCS2 TDO2 PLG	1.07e-06	165	90	6	d449a568664a81d9b5538e8f409301448a32ac37
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK6 ENTPD5 C1S HMGCS2 TDO2 PLG	1.19e-06	168	90	6	b98af4043dfa5dfa4413e482879fad88de484675
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK6 ENTPD5 C1S HMGCS2 TDO2 PLG	1.19e-06	168	90	6	073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCell	droplet-Liver-HEPATOCYTES\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK6 ENTPD5 C1S HMGCS2 TDO2 PLG	1.23e-06	169	90	6	f195467438c589f87224bde7da720dea072d110c
ToppCell	droplet-Liver-HEPATOCYTES-1m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK6 ENTPD5 C1S HMGCS2 TDO2 PLG	1.23e-06	169	90	6	7785cab967a33560830c394c918d6ce625103858
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Lymphocytic-B_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UCP2 SCN4A CD79A CR2 ITGAX HCLS1	1.41e-06	173	90	6	a693772987f1baee533dd0bd285a3c7b5619a73b
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK6 ENTPD5 C1S TDO2 PLG ATP1B1	1.51e-06	175	90	6	5c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCell	Mild/Remission-B_intermediate-10\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PIKFYVE RTP5 PCSK6 ENC1 ITGAX CEMIP2	1.96e-06	183	90	6	278064c9f0582463b83bf156d34e77f60187613b
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIKFYVE MYCBP2 CD79A KDM6B PARP14 CR2	2.08e-06	185	90	6	e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCell	COVID-19_Convalescent-CD8+_T_naive\|COVID-19_Convalescent / Disease condition and Cell class	RPL30 FLNB UMODL1 PCSK6 CD79A KDM6B	2.08e-06	185	90	6	2f8277a0b58fb0c49fa76ff6dfa6da961da1f9f5
ToppCell	facs-Heart-RA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIMP3 PCSK6 ENC1 C1S HMGCS2 ADAMTSL2	2.74e-06	194	90	6	48063c9fe3e12aeff0707acada1baa2f8621f093
ToppCell	facs-Heart-RA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIMP3 PCSK6 ENC1 C1S HMGCS2 ADAMTSL2	2.74e-06	194	90	6	4f31d2cf7eb37b45fefc4da5b41aac0bfdd847b3
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TIMP3 KLHL13 ENC1 C1S C7 SVEP1	2.91e-06	196	90	6	525d6c8a277364e624e7cc586275f8a891436b57
ToppCell	368C-Fibroblasts-Fibroblast-G\|368C / Donor, Lineage, Cell class and subclass (all cells)	TIMP3 C1S TDO2 C7 SVEP1 ADAMTSL2	2.99e-06	197	90	6	156155c2f0c1a2461e45803da578af18ee221660
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SH3TC1 UCP2 KDM6B ITGAX SSPOP ADAMTSL2	2.99e-06	197	90	6	b597c292fc1cb381a4325fed15a32966c38def28
ToppCell	368C-Fibroblasts-Fibroblast-G-\|368C / Donor, Lineage, Cell class and subclass (all cells)	TIMP3 C1S TDO2 C7 SVEP1 ADAMTSL2	2.99e-06	197	90	6	d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TIMP3 C1S TDO2 C7 SVEP1 ADAMTSL2	2.99e-06	197	90	6	4cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCell	Severe-B_intermediate-10\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PIKFYVE PCSK6 ENC1 CD79A ITGAX CEMIP2	3.08e-06	198	90	6	dfae26c3513a82bb7cb8dadbfcea2a1f420b1bab
ToppCell	wk_08-11-Mesenchymal-Fibroblast-intermediate_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	RPL30 C1S TDO2 C7 SVEP1 FREM1	3.17e-06	199	90	6	f9e3fb974ba8fe1b6d99892577549ef143df9e08
ToppCell	ILEUM-inflamed-(8)_Fibroblasts\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FLNB TIMP3 C1S TDO2 C7 SVEP1	3.17e-06	199	90	6	3a3e2bb21cd0293622b1a975263e918d9ba24265
ToppCell	Severe-B_intermediate-6\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PIKFYVE FLNB UCP2 ENC1 CD79A ITGAX	3.17e-06	199	90	6	bf6ebb63ab361d9d1946225894d7be433e9befab
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	MYCBP2 C1S C7 SVEP1 FREM1 CEMIP2	3.27e-06	200	90	6	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-C1ql2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SPINT1 UMODL1 TDO2 IGSF1 ADAMTSL2	3.54e-06	114	90	5	f48fd7d378626eb7ef972ff1df87dd6149cb355c
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Hpgd\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PAPPA2 ENC1 TDO2 C7 MDGA1	5.78e-06	126	90	5	9b04ca8a46cc30119baf6ef27711a0b2a6b4a0c9
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-C1ql2-Excitatory_Neuron.Slc17a7.C1ql2-Cck_(Dentate_Principal_cells)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SPINT1 UMODL1 TDO2 IGSF1 ADAMTSL2	6.48e-06	129	90	5	08ecebb7f09d105dfdfd2191fc310910d3baec0f
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_PT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PAPPA2 ENC1 TDO2 C7 LRRC9	7.80e-06	134	90	5	cb676d5bbc468bd3ce1b6712d41c986ee9221ac5
ToppCell	Mild/Remission-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RTP5 PCSK6 ENC1 ITGAX CEMIP2	8.38e-06	136	90	5	1b3c6edcbe0eb674d2d9c838e83ebe2b93e3eec1
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX6 C1S HMGCS2 TDO2 PLG	1.39e-05	151	90	5	e243b6c76e59035f10519a86399b598dd2123f87
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX6 C1S HMGCS2 TDO2 PLG	1.39e-05	151	90	5	cdd2ce0969da446616627e3569bbe5a5d9b475bd
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX6 C1S HMGCS2 TDO2 PLG	1.53e-05	154	90	5	a5289000597068ee8d559f89bce7bce31f35dd57
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1\|E16.5-samps / Age Group, Lineage, Cell class and subclass	C1S C7 TMEM38B SVEP1 ADAMTSL2	2.01e-05	163	90	5	f1ec2625b52664308968b01d8e0275e1e0751480
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SH3TC1 KDM6B PARP14 ITGAX ADAMTSL2	2.01e-05	163	90	5	a6e272e043859858084b8d4d96fa4ff9e6eca454
ToppCell	367C-Fibroblasts-Fibroblast-G\|367C / Donor, Lineage, Cell class and subclass (all cells)	TDRD9 TIMP3 C1S C7 MDGA1	2.33e-05	168	90	5	8c95093b1ea45826f62893edd3c410fe53b563a4
ToppCell	367C-Fibroblasts-Fibroblast-G-\|367C / Donor, Lineage, Cell class and subclass (all cells)	TDRD9 TIMP3 C1S C7 MDGA1	2.33e-05	168	90	5	b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCell	-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	C1S CD79A C7 SVEP1 ADAMTSL2	2.39e-05	169	90	5	8ebe9a88111c53a09c25a7b6a164a0a17880458d
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C1S RIMBP2 PLCB4 TDO2 C7	2.39e-05	169	90	5	559e98216720e4babf0b0941100f1b485c35b11b
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8\|TCGA-Liver / Sample_Type by Project: Shred V9	SCN4A ENTPD5 C1S TDO2 C7	2.53e-05	171	90	5	c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF512B MDGA1 KLHDC4 FREM1 LRRC9	2.60e-05	172	90	5	e15ab284df6dd241d4481f98864b18c39d757b8c
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 KIF1A SH3TC1 TIMP3 CEMIP2	2.60e-05	172	90	5	a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SETD2 KIF1A RIMBP2 ADGRV1 MYO15A	2.75e-05	174	90	5	271c51d220842402975d97c86c9acfdbdf62a32c
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TIMP3 MDGA2 PLCB4 ATP1B1 FREM1	2.75e-05	174	90	5	66df78280f657978c4a568010ae7d7943869af90
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 KIF1A SH3TC1 TIMP3 CEMIP2	2.91e-05	176	90	5	3494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCell	droplet-Liver-Npc-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 KIF1A SH3TC1 TIMP3 CEMIP2	2.91e-05	176	90	5	d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	TIMP3 C1S TDO2 C7 SVEP1	2.99e-05	177	90	5	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	TIMP3 C1S TDO2 C7 SVEP1	2.99e-05	177	90	5	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	Severe-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PIKFYVE PCSK6 ENC1 ITGAX CEMIP2	3.07e-05	178	90	5	b7374a97c51239782bed658381a02cb1b3d9bf66
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3TC1 TIMP3 ENC1 PLCB4 NXPE3	3.15e-05	179	90	5	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-Pro-B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RTP5 SH3TC1 UMODL1 UCP2 CD79A	3.24e-05	180	90	5	e76ccbaba18ff27abbd71a41fd3574a5ac5c8fb4
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIKFYVE MYCBP2 CD79A KDM6B CR2	3.41e-05	182	90	5	5f1f10c845b73d1f69794277925ef847ff23ac2d
ToppCell	droplet-Tongue-nan-24m-Epithelial-keratinocyte\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPINT1 MYCBP2 FDPS ENTPD5 KIF1C	3.50e-05	183	90	5	9e6c96ada930e8559246a270dfc69fb3cbb3bdf3
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MELTF C1S C7 SVEP1 ADAMTSL2	3.69e-05	185	90	5	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIMP3 PCSK6 C1S C7 SVEP1	3.78e-05	186	90	5	ff6ccfdf2509f96caa10281c29a95b432f6c6dcc
ToppCell	facs-Spleen-nan-3m-Lymphocytic-CD79a_B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL24 TIMP3 CD79A HMGCS2 CR2	3.88e-05	187	90	5	b51af2824e65734f333b1325117f4a2e88b17c23
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 KLHL13 RIMBP2 ADGRV1 ATP1B1	3.88e-05	187	90	5	7ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM14A ENC1 DDX43 PLG SSPOP	3.88e-05	187	90	5	8c69fd469df2915c56ede534cee3ef23d5f64ebf
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	TMEM131L TMEM131 PARP14 MED13 CEMIP2	3.98e-05	188	90	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	TIMP3 C1S C7 SVEP1 ADAMTSL2	3.98e-05	188	90	5	038f48e8daaeb72716e975d22a6b004a90654960
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 KLHL13 RIMBP2 ADGRV1 ATP1B1	3.98e-05	188	90	5	2ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCell	wk_15-18-Hematologic_Lymphocytic-B-small_pre-B-II_cell\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	UMODL1 UCP2 TMEM131L CD79A PLG	3.98e-05	188	90	5	56d78b5a86a71b2e752db379f4a46dc4c623b553
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 KLHL13 RIMBP2 ADGRV1 ATP1B1	3.98e-05	188	90	5	3cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 KLHL13 RIMBP2 ADGRV1 ATP1B1	4.08e-05	189	90	5	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	Smart-seq2-spleen_(Smart-seq2)\|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	UCP2 CD79A KDM6B CR2 CEMIP2	4.08e-05	189	90	5	b0244a9d1b5c8ad4708750b691184f3491b13900
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RPL30 C1S C7 SVEP1 ADAMTSL2	4.08e-05	189	90	5	9e1a51997ef9b6999d9b40cf0a55e561e3b4a84c
ToppCell	CTRL-Lymphoid-B_cell\|Lymphoid / Disease state, Lineage and Cell class	PIKFYVE TMEM131L CD79A PARP14 ITGAX	4.08e-05	189	90	5	14f3a8c0f4f057ad4e6839b4c3eeaf956d6dc92e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TIMP3 KLHL13 C7 SVEP1 ADAMTSL2	4.08e-05	189	90	5	c734e5693808a0333139e87bd5be2597a9252afe
ToppCell	facs-SCAT-Fat-24m-Mesenchymal-mesenchymal_progenitor\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIMP3 C1S HMGCS2 C7 SVEP1	4.19e-05	190	90	5	dc7e92f1b18d0f5efec11d09d56ba954d4f8b3bd
ToppCell	facs-SCAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIMP3 C1S HMGCS2 C7 SVEP1	4.19e-05	190	90	5	0bb06df3d5a50416854370f234718c6cec3d773b
ToppCell	facs-SCAT-Fat-24m-Mesenchymal\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIMP3 C1S HMGCS2 C7 SVEP1	4.19e-05	190	90	5	008290bb5c79446681dd6bf354336c57ad0d6f13
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TIMP3 KLHL13 C7 SVEP1 ADAMTSL2	4.19e-05	190	90	5	2e592323085ba9c019d678ac2a784462ab470ed9
ToppCell	facs-GAT-Fat-24m-Mesenchymal\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIMP3 C1S HMGCS2 C7 SVEP1	4.19e-05	190	90	5	3720e64129f3f3268b1dc14031a76f41c38241c2
ToppCell	facs-GAT-Fat-24m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIMP3 C1S HMGCS2 C7 SVEP1	4.19e-05	190	90	5	73a50426f972f08f9bb525ad5c0b774187ab5d6a
ToppCell	facs-GAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIMP3 C1S HMGCS2 C7 SVEP1	4.19e-05	190	90	5	b55cf1fb586b724295b7b038483249847bb344fc
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TIMP3 KLHL13 C7 SVEP1 ADAMTSL2	4.19e-05	190	90	5	445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TIMP3 KLHL13 C7 SVEP1 ADAMTSL2	4.29e-05	191	90	5	c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell	Severe-Treg\|World / Disease group and Cell class	GK SH3TC1 UCP2 CD79A ADGRV1	4.29e-05	191	90	5	0a80b8c317e8da4d4722cfd13cdabc32b58021eb
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TIMP3 KLHL13 C7 SVEP1 ADAMTSL2	4.29e-05	191	90	5	806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TIMP3 KLHL13 C7 SVEP1 ADAMTSL2	4.29e-05	191	90	5	cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TIMP3 TMEM131L MDGA2 PLCB4 C7	4.29e-05	191	90	5	7b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TIMP3 TMEM131L MDGA2 PLCB4 C7	4.29e-05	191	90	5	cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCell	PND14-Mesenchymal-Mesenchymal_structural\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	C1S C7 SVEP1 FREM1 ADAMTSL2	4.40e-05	192	90	5	25492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KLHL25 SVEP1 FREM1 AFF4 CEMIP2	4.40e-05	192	90	5	6bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCell	B_cells-Memory_B_cells\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	RPL30 UCP2 TMEM131L CD79A CR2	4.40e-05	192	90	5	eef591095921ede098f41a2b81897b18915bb753
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 KLHL13 RIMBP2 ADGRV1 ATP1B1	4.40e-05	192	90	5	562df5e87038c500dd3a003fe5374cb31946b145
ToppCell	facs-Lung-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TIMP3 C1S C7 SVEP1 ADAMTSL2	4.40e-05	192	90	5	8df15085b35b86f39debd933284cb703c5dd63c2
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	C1S C7 SVEP1 FREM1 ADAMTSL2	4.40e-05	192	90	5	de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KLHL13 C1S C7 SVEP1 FREM1	4.40e-05	192	90	5	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLCB4 C7 ATP1B1 SVEP1 FREM1	4.40e-05	192	90	5	20ede290e01ad574afd122d72b59dbc52c595fad
ToppCell	moderate-Lymphoid-B_cell\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PIKFYVE CD79A TMEM131 KDM6B CR2	4.40e-05	192	90	5	ae3727503c3b9f4695e565fd3161cc33b898f349
ToppCell	PND28-Mesenchymal-Mesenchymal_structural\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TIMP3 C1S C7 SVEP1 ADAMTSL2	4.51e-05	193	90	5	ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
Computational	Genes in the cancer module 58.	C1S C7 CR2	1.85e-04	21	58	3	MODULE_58
Computational	Complement.	C1S C7 CR2	2.45e-04	23	58	3	MODULE_130
Drug	Etiocobalamin	PCSK6 C1S CD79A PLG CR2 ITGAX PGM3	6.61e-06	177	90	7	CID006450878
Drug	Lidocaone hydrochloride [73-78-9]; Down 200; 14.8uM; MCF7; HT_HG-U133A	KLHL24 KLHL25 TIMP3 PCSK6 CD79A KIF1C NXPE3	1.05e-05	190	90	7	4421_DN
Drug	Gallamine triethiodide [65-29-2]; Down 200; 4.4uM; HL60; HG-U133A	SLC25A24 KLHL24 TMEM14A KDM6B RFX5 TMEM38B MED13	1.16e-05	193	90	7	1375_DN
Drug	Nafcillin sodium salt monohydrate [7177-50-6]; Up 200; 8.8uM; MCF7; HT_HG-U133A	PAPPA2 KLHL25 TIMP3 ZMIZ2 PCSK6 CD79A KIF1C	1.37e-05	198	90	7	4103_UP
Drug	Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; PC3; HT_HG-U133A	PAPPA2 KLHL25 C1S CD79A RIMBP2 C7 KIF1C	1.42e-05	199	90	7	3759_UP
Disease	nervous system disease (implicated_via_orthology)	KIF1A KIF1B KIF1C	5.34e-06	12	87	3	DOID:863 (implicated_via_orthology)
Disease	acute graft vs. host disease, donor genotype effect measurement	SLC25A24 MDGA2 TMEM131	1.10e-05	15	87	3	EFO_0004599, EFO_0007892
Disease	synucleinopathy (biomarker_via_orthology)	KIF1A KIF1B	5.14e-05	4	87	2	DOID:0050890 (biomarker_via_orthology)
Disease	hereditary sensory neuropathy (is_implicated_in)	KIF1A DNMT1	5.14e-05	4	87	2	DOID:0050548 (is_implicated_in)
Disease	calcineurin subunit B type 1 measurement	PCSK6 C7	1.79e-04	7	87	2	EFO_0020215
Disease	cytochrome c oxidase assembly factor 3 homolog, mitochondrial measurement	PIKFYVE C7	2.38e-04	8	87	2	EFO_0801513
Disease	Leigh syndrome	PDHA1 SCN4A	2.38e-04	8	87	2	cv:C0023264
Disease	cytochrome c oxidase subunit 4 isoform 2, mitochondrial measurement	PIKFYVE C7	3.05e-04	9	87	2	EFO_0801514
Disease	RNA-binding protein 24 measurement	PIKFYVE C7	3.05e-04	9	87	2	EFO_0802030
Disease	Facies	AFF4 ADAMTSL2	3.81e-04	10	87	2	C0282631
Disease	DNA-directed RNA polymerases I and III subunit RPAC1 measurement	PIKFYVE C7	3.81e-04	10	87	2	EFO_0801535
Disease	guanylate-binding protein 6 measurement	PIKFYVE C7	4.65e-04	11	87	2	EFO_0801662
Disease	homostachydrine measurement	ACSL6 PLCB4	6.56e-04	13	87	2	EFO_0021164
Disease	T-cell surface glycoprotein CD3 epsilon chain measurement	PIKFYVE ATP1B1	6.56e-04	13	87	2	EFO_0802114
Disease	HbA1c measurement	FDPS GPX6 TMEM131L C1S MYO15A CR2 ITGAX KIF1C	8.60e-04	675	87	8	EFO_0004541
Disease	reticulocyte count	PIKFYVE FLNB KLHL10 FDPS ENC1 TMEM131L TMEM131 ITGAX DNMT1 KIF1C	1.01e-03	1045	87	10	EFO_0007986
Disease	Hypogammaglobulinemia	CD79A CR2	1.14e-03	17	87	2	C0086438
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	SETD2 MED13	1.14e-03	17	87	2	DOID:0060307 (is_implicated_in)
Disease	birth weight	ZNF512B PAPPA2 KLHL24 KLHL25 UMODL1 DNMT1	1.18e-03	399	87	6	EFO_0004344
Disease	tissue plasminogen activator measurement, coronary artery disease	GPX6 ATP1B1 MAP3K4	1.22e-03	71	87	3	EFO_0001645, EFO_0004791
Disease	Lupus Erythematosus, Systemic	IRAK4 C1S CR2	1.22e-03	71	87	3	C0024141
Disease	cytotoxicity measurement, response to metformin	KIF1A SH3TC1	1.74e-03	21	87	2	EFO_0006952, GO_1901558
Disease	neutrophil count	PAPPA2 SLC25A24 FLNB SETD2 MYCBP2 ZNF92 KIF1B PLCB4 KDM6B ATP1B1 DNMT1	2.44e-03	1382	87	11	EFO_0004833
Disease	birth weight, parental genotype effect measurement	ZNF512B PAPPA2 KLHL25 DNMT1	2.54e-03	192	87	4	EFO_0004344, EFO_0005939
Disease	chylomicron measurement, triglyceride measurement, very low density lipoprotein cholesterol measurement	PCSK6 TNKS PLG	2.90e-03	96	87	3	EFO_0004530, EFO_0008317, EFO_0008596

Protein segments in the cluster

Peptide	Gene	Start	Entry
GVLYRVKTSYQGCGA	UMODL1	371	Q5DID0
NYGVKSVGQGYSVGQ	ADNP	331	Q9H2P0
VYCRNTGGRYGKATI	PGM3	166	O95394
LGNCSGLNDETYGYK	ATP1B1	156	P05026
GYQCTFGVLQAGQYG	DNMT1	1291	P26358
DGNGSIYYGVKIQTN	ADGRV1	1376	Q8WXG9
GGIYVCRVQEGNESY	CD79A	101	P11912
GYKKEGREQGTGNSY	AFF4	501	Q9UHB7
VYLGEEYCGTSRGKN	PAAT	101	Q9H8K7
LGGRGQSKYCYSGIR	RFX5	151	P48382
GLSYRYVAEGQKQGQ	ITGAX	826	P20702
YQKVPSSGYGQQGIS	LRRC9	1171	Q6ZRR7
TQGGRYYCKAENGVG	MDGA1	101	Q8NFP4
VKYQYGGNQEGEVGF	ENTPD5	286	O75356
QIGQAKNTYGTGCFL	GK3P	271	Q14409
YYLNQGGNCEIAGKS	MYO15A	1436	Q9UKN7
EYNAIGGKYNRGLTV	FDPS	116	P14324
VCIFAYGQTGAGKSY	KIF1B	91	O60333
DYNTAKGVLGAGYQA	IKBKE	411	Q14164
LEGQKYCYRGTGAAV	KDM6B	811	O15054
KAYNLRSVAVYGGGS	DDX42	351	Q86XP3
YNNVEAGKYTVGLGQ	HMGCS2	76	P54868
GSCGVSYIAQEPGNY	FLNB	2246	O75369
SYCIVGIAYNAKIGG	PCSK6	261	P29122
VGQKYGIRNAGYYAL	PDPR	696	Q8NCN5
PSQVGLLKNGCYGIY	FREM1	1636	Q5H8C1
VCIFAYGQTGAGKSY	KIF1C	91	O43896
VTGNYRKGNAHLGYS	ADAMTSL2	216	Q86TH1
IAYGGNNYVVIGTCT	NUP37	36	Q8NFH4
YTQIVYIGDGGNDVC	PHOSPHO2	171	Q8TCD6
YGVYNCSIINEAGAG	MDGA2	606	Q7Z553
GFNRSYAGKNAVAYG	PARP14	1696	Q460N5
NSVEYKCEQGYGIGA	PAPPA2	1661	Q9BXP8
RGADSAYYQVGQTGK	PIKFYVE	1766	Q9Y2I7
GYCTQIGIFRKNGGK	HENMT1	221	Q5T8I9
VEGKGIGNYSCSYRL	IGSF1	1216	Q8N6C5
LYGKVYICGGFNGNE	KLHL10	431	Q6JEL2
LYVVGGQSNYDTKGK	KLHL13	391	Q9P2N7
LGKVYVVGGYDGQNR	KLHL24	406	Q6TFL4
SGNKLYVVGGYFGTQ	KLHL25	536	Q9H0H3
YVVGGYFGTQRCKTL	KLHL25	541	Q9H0H3
GEGYKLSGSVYQECQ	CR2	496	P20023
SVAVYGQYGGQPCVG	C7	51	P10643
GPQCGTYGLYTRVKN	C1S	656	P09871
FQIGQAKNTYGTGCF	GK	276	P32189
RNYGFQGGQNKYVGT	CEMIP2	836	Q9UHN6
QGGIVVYGGYSKQRV	KLHDC4	241	Q8TBB5
GFGVVYKGYVNNTTV	IRAK4	196	Q9NWZ3
SGNKLYVVGGYFGIQ	ENC1	536	O14682
DCNKGVTGTIYEYGA	GPX6	31	P59796
YKGLRSVCVYGGGNR	DDX43	341	Q9NXZ2
VCIFAYGQTGAGKSY	KIF1A	91	Q12756
GNKIGEGQYGKVYTC	MAP3K4	1346	Q9Y6R4
GNGCFSQGYYQKRQL	RTP5	496	Q14D33
GANVTGYGVYAKGQR	RIMBP2	521	O15034
PQEKAGQCRGYEIYG	TRIM45	376	Q9H8W5
GQCRGYEIYGTINTK	TRIM45	381	Q9H8W5
NQGKFEYNGSCGYLL	PLCB4	661	Q15147
EGYECIKTGRNPNYG	SCN4A	371	P35499
GQGCRYSLVQDYVKG	SSPOP	586	A2VEC9
GRNKCVGNSQERYYG	MELTF	541	P08582
VSSLKINGYNCQGYG	TMEM131L	781	A2VDJ0
GVNRASKGGLIYGNY	TDO2	31	P48775
DQNGKYYTGVLCGLG	TDRD9	1241	Q8NDG6
SQRDYAKGFGGQYGI	HCLS1	186	P14317
GAVGRVVDYQNGFYK	NXPE3	156	Q969Y0
YGLYCVQSGGKNIRV	PIP5K1C	221	O60331
CTRQGPAQQGKGYYE	SH3TC1	956	Q8TE82
YYTGKYQSLGIKQGG	MYCBP2	551	O75592
GEAGQKYNVLFVGYC	MED13	1781	Q9UHV7
PTYQCLKGTGENYRG	PLG	271	P00747
SYRGGGTYTKGAFQQ	SVEP1	161	Q4LDE5
LRAALGCQVYEGYGQ	ACSL6	446	Q9UKU0
GGGRRYQSTVNAYKT	UCP2	151	P55851
DACKVYKGGYNGLNQ	ZNF92	121	Q03936
SAGLYYTGIGDQVQC	XIAP	186	P98170
YAKNFYGGNGIVGAQ	PDHA1	156	P08559
GNNIELGTACGKYYR	RPL30	76	P62888
GVIIYNYQGTGSKVF	RNF148	126	Q8N7C7
KSFVYGGCLGNKNNY	SPINT1	276	O43278
ENSSKSNQYVYGIGG	TNKS	1216	O95271
ISGYSCEGYGFKVVN	TMEM131	1036	Q92545
IVGGVTHANSYYKNG	TMEM38B	126	Q9NVV0
CQNGKYAVIGTYDGR	WDR44	701	Q5JSH3
GCLAGYGAYRVSNDK	TMEM14A	36	Q9Y6G1
QKGYVGDGLTCYGNI	STAB2	351	Q8WWQ8
AGGFVYTYKLVNNGE	SF3B3	921	Q15393
CGGHKYQQNAEQYGG	SETD2	1281	Q9BYW2
EGGANKGYVQQGVYS	ZMIZ2	96	Q8NF64
GLKYHYQRCQGGAIS	ZNF512B	121	Q96KM6
GTLYCAKGNYEFGIS	TTC30A	551	Q86WT1
VQTPQGQDYAGKCYA	UCKL1	376	Q9NWZ5
GQDYAGKCYAGKQIT	UCKL1	381	Q9NWZ5
LAVGKTGQYSGIYDC	SLC25A24	316	Q6NUK1
GYQSKHYACIRQKGG	TIMP3	176	P35625
TGQKRLYYVGHSQGT	LIPK	161	Q5VXJ0