Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnuclear receptor binding

WBP2 NCOR2 SMARCA4 ARID1A LEF1 ARID5A

1.52e-05187576GO:0016922
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DENND4A DENND10 GNA13 RAPGEF2 ECT2 VAV2

4.98e-05231576GO:0005085
GeneOntologyMolecularFunctionTPR domain binding

PDE2A HSP90AB1

2.22e-048572GO:0030911
GeneOntologyMolecularFunctionRNA polymerase I core promoter sequence-specific DNA binding

UBTFL6 SMARCA4

4.33e-0411572GO:0001164
GeneOntologyMolecularFunctionnuclear estrogen receptor binding

WBP2 LEF1 ARID5A

4.67e-0453573GO:0030331
GeneOntologyMolecularFunctiontranscription corepressor activity

NCOR2 SMARCA4 CDY2A ARID5A CDY1

4.89e-04229575GO:0003714
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DENND4A DENND10 GNA13 RAPGEF2 ECT2 RGS1 VAV2

5.76e-04507577GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

DENND4A DENND10 GNA13 RAPGEF2 ECT2 RGS1 VAV2

5.76e-04507577GO:0030695
GeneOntologyMolecularFunctionRNA polymerase I transcription regulatory region sequence-specific DNA binding

UBTFL6 SMARCA4

6.12e-0413572GO:0001163
GeneOntologyMolecularFunctioncGMP binding

PDE2A RAPGEF2

9.36e-0416572GO:0030553
GeneOntologyMolecularFunctiontranscription coregulator activity

WBP2 NCOR2 SMARCA4 CDY2A ARID1A ARID5A CDY1

1.05e-03562577GO:0003712
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

WBP2 NCOR2 SMARCA4 ARID1A LEF1 ARID5A

1.18e-03417576GO:0061629
GeneOntologyMolecularFunctionnuclear import signal receptor activity

KPNA5 KPNA6

1.47e-0320572GO:0061608
GeneOntologyMolecularFunctionDNA polymerase binding

SMARCA4 HSP90AB1

1.95e-0323572GO:0070182
GeneOntologyMolecularFunctionnuclear retinoid X receptor binding

NCOR2 ARID5A

1.95e-0323572GO:0046965
GeneOntologyMolecularFunctionG-protein beta/gamma-subunit complex binding

GNA13 PLCB2

2.30e-0325572GO:0031683
GeneOntologyMolecularFunctioncAMP binding

PDE2A RAPGEF2

2.30e-0325572GO:0030552
GeneOntologyMolecularFunctiondopamine receptor binding

GNA13 PALM

2.49e-0326572GO:0050780
GeneOntologyMolecularFunctionnuclear localization sequence binding

KPNA5 KPNA6

2.68e-0327572GO:0008139
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

PDE2A NPR3 PALM CHRM2 RGS1

4.31e-0686585GO:0007193
GeneOntologyBiologicalProcesschordate embryonic development

NCOR2 TCF7 UBTFL6 RBBP6 GNA13 DAB2 SMARCA4 APOB ATM ACVR1C ARID1A LEF1

6.61e-069065812GO:0043009
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

NCOR2 TCF7 UBTFL6 RBBP6 GNA13 DAB2 SMARCA4 APOB ATM ACVR1C ARID1A LEF1

8.53e-069295812GO:0009792
GeneOntologyBiologicalProcessandrogen receptor signaling pathway

NCOR2 DAB2 SMARCA4 ARID1A

1.27e-0551584GO:0030521
GeneOntologyBiologicalProcessnegative regulation of androgen receptor signaling pathway

NCOR2 DAB2 SMARCA4

1.40e-0517583GO:0060766
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

PDE2A NPR3 GNA13 PALM RAPGEF2 CHRM2 RGS1

1.50e-05286587GO:0007188
GeneOntologyBiologicalProcessembryo development

NCOR2 TCF7 UBTFL6 ACTR5 RBBP6 GNA13 DAB2 SMARCA4 APOB ATM ACVR1C ARID1A LEF1 DISP1

3.30e-0514375814GO:0009790
GeneOntologyBiologicalProcessV(D)J recombination

TCF7 ATM LEF1

3.59e-0523583GO:0033151
GeneOntologyBiologicalProcessin utero embryonic development

NCOR2 UBTFL6 RBBP6 GNA13 DAB2 SMARCA4 APOB ACVR1C LEF1

3.98e-05596589GO:0001701
GeneOntologyBiologicalProcessnuclear receptor-mediated steroid hormone signaling pathway

WBP2 NCOR2 DAB2 SMARCA4 ARID1A

4.01e-05136585GO:0030518
GeneOntologyBiologicalProcessepithelium development

ENAM NCOR2 PDE2A TCF7 RBBP6 GNA13 DAB2 PKHD1 SMARCA4 RAB1B ATM RAPGEF2 ARID1A LEF1

4.21e-0514695814GO:0060429
GeneOntologyBiologicalProcesscellular response to organic cyclic compound

WBP2 KIF18A NCOR2 PDE2A DAB2 SMARCA4 PALM RAPGEF2 ARID1A

4.47e-05605589GO:0071407
GeneOntologyBiologicalProcessblood vessel development

SCN11A PDE2A NPR3 GNA13 SMARCA4 APOB RAPGEF2 ARID1A FASLG LEF1 VAV2

4.76e-059295811GO:0001568
GeneOntologyBiologicalProcessvasculature development

SCN11A PDE2A NPR3 GNA13 SMARCA4 APOB RAPGEF2 ARID1A FASLG LEF1 VAV2

6.96e-059695811GO:0001944
GeneOntologyBiologicalProcesssteroid hormone receptor signaling pathway

WBP2 NCOR2 DAB2 SMARCA4 ARID1A

7.47e-05155585GO:0043401
GeneOntologyBiologicalProcesssomatic recombination of T cell receptor gene segments

TCF7 LEF1

7.73e-055582GO:0002681
GeneOntologyBiologicalProcessT cell receptor V(D)J recombination

TCF7 LEF1

7.73e-055582GO:0033153
GeneOntologyBiologicalProcesssomatic diversification of T cell receptor genes

TCF7 LEF1

7.73e-055582GO:0002568
GeneOntologyBiologicalProcesscellular response to abiotic stimulus

PDE2A ACTR5 PALM ATM ECT2 TMEM87A MICU1

7.86e-05371587GO:0071214
GeneOntologyBiologicalProcesscellular response to environmental stimulus

PDE2A ACTR5 PALM ATM ECT2 TMEM87A MICU1

7.86e-05371587GO:0104004
GeneOntologyBiologicalProcessregulation of androgen receptor signaling pathway

NCOR2 DAB2 SMARCA4

8.97e-0531583GO:0060765
GeneOntologyBiologicalProcessregulation of intracellular steroid hormone receptor signaling pathway

WBP2 NCOR2 DAB2 SMARCA4

1.05e-0487584GO:0033143
GeneOntologyBiologicalProcessblastocyst growth

UBTFL6 SMARCA4 ACVR1C

1.08e-0433583GO:0001832
GeneOntologyBiologicalProcesstube development

KIF18A NCOR2 NPR3 TCF7 GNA13 PKHD1 SMARCA4 APOB RAPGEF2 ARID1A FASLG LEF1 VAV2

1.11e-0414025813GO:0035295
GeneOntologyBiologicalProcesstelomerase holoenzyme complex assembly

ATM HSP90AB1

1.16e-046582GO:1905323
GeneOntologyBiologicalProcesscirculatory system development

NCOR2 SCN11A PDE2A NPR3 GNA13 SMARCA4 APOB ATM RAPGEF2 ARID1A FASLG LEF1 VAV2

1.47e-0414425813GO:0072359
GeneOntologyBiologicalProcesscellular response to cGMP

PDE2A RAPGEF2

1.62e-047582GO:0071321
GeneOntologyBiologicalProcesscellular response to interleukin-4

TCF7 LEF1 HSP90AB1

1.66e-0438583GO:0071353
GeneOntologyBiologicalProcessnegative regulation of intracellular steroid hormone receptor signaling pathway

NCOR2 DAB2 SMARCA4

1.94e-0440583GO:0033144
GeneOntologyBiologicalProcessresponse to interleukin-4

TCF7 LEF1 HSP90AB1

2.08e-0441583GO:0070670
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

WBP2 NCOR2 DAB2 SMARCA4 ARID1A

2.58e-04202585GO:0141193
GeneOntologyBiologicalProcesstube morphogenesis

NPR3 TCF7 GNA13 PKHD1 SMARCA4 APOB RAPGEF2 ARID1A FASLG LEF1 VAV2

2.59e-0411255811GO:0035239
GeneOntologyBiologicalProcessresponse to cGMP

PDE2A RAPGEF2

2.76e-049582GO:0070305
GeneOntologyBiologicalProcessRNA polymerase I preinitiation complex assembly

UBTFL6 SMARCA4

4.21e-0411582GO:0001188
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

NCOR2 PDE2A TCF7 DAB2 SMARCA4 CDY2A ARID1A FASLG LEF1 ARID5A NKRF CDY1

4.35e-0413995812GO:0045892
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

NCOR2 PDE2A TCF7 DAB2 SMARCA4 CDY2A ARID1A FASLG LEF1 ARID5A NKRF CDY1

4.76e-0414135812GO:1902679
GeneOntologyBiologicalProcessartery development

SCN11A PDE2A SMARCA4 APOB

5.35e-04133584GO:0060840
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

WBP2 NCOR2 DAB2 SMARCA4 ARID1A

5.57e-04239585GO:0071383
GeneOntologyBiologicalProcessestablishment of endothelial barrier

PDE2A RAB1B RAPGEF2

5.83e-0458583GO:0061028
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

WBP2 NCOR2 DAB2 SMARCA4 ARID1A

6.11e-04244585GO:0009755
GeneOntologyBiologicalProcessnuclear transport

KPNA5 WASHC4 NXF2 KPNA6 ECT2 HSP90AB1

6.60e-04378586GO:0051169
GeneOntologyBiologicalProcessnucleocytoplasmic transport

KPNA5 WASHC4 NXF2 KPNA6 ECT2 HSP90AB1

6.60e-04378586GO:0006913
GeneOntologyBiologicalProcessepithelial cell differentiation

ENAM NCOR2 PDE2A DAB2 PKHD1 SMARCA4 RAB1B RAPGEF2 LEF1

6.74e-04870589GO:0030855
GeneOntologyBiologicalProcessintracellular transport

KPNA5 DENND10 WASHC4 AP3B2 DAB2 NXF2 KPNA6 RAB1B TRAPPC8 ECT2 TMEM87A HSP90AB1

7.93e-0414965812GO:0046907
GeneOntologyBiologicalProcessregulation of gamma-delta T cell differentiation

TCF7 LEF1

7.97e-0415582GO:0045586
GeneOntologyBiologicalProcesstranscription initiation-coupled chromatin remodeling

WBP2 SMARCA4 ARID1A

8.14e-0465583GO:0045815
GeneOntologyBiologicalProcessestablishment of organelle localization

KIF18A SCN11A AP3B2 PKHD1 ATM TRAPPC8 ECT2

8.19e-04546587GO:0051656
GeneOntologyBiologicalProcesspositive regulation of gene expression, epigenetic

WBP2 SMARCA4 ARID1A

9.29e-0468583GO:0141137
GeneOntologyBiologicalProcessepithelial cell development

PDE2A PKHD1 SMARCA4 RAB1B RAPGEF2

9.48e-04269585GO:0002064
GeneOntologyBiologicalProcessregulation of gamma-delta T cell activation

TCF7 LEF1

1.03e-0317582GO:0046643
GeneOntologyBiologicalProcessestablishment of endothelial intestinal barrier

RAB1B RAPGEF2

1.03e-0317582GO:0090557
GeneOntologyBiologicalProcesspositive regulation by host of viral transcription

SMARCA4 LEF1

1.03e-0317582GO:0043923
GeneOntologyBiologicalProcesslipoprotein catabolic process

APOB ATM

1.03e-0317582GO:0042159
GeneOntologyBiologicalProcessresponse to lipid

WBP2 KIF18A NCOR2 SCN11A DAB2 SMARCA4 ATM ARID1A FASLG ARID5A

1.08e-0311265810GO:0033993
GeneOntologyBiologicalProcessintracellular receptor signaling pathway

WBP2 NCOR2 WASHC4 DAB2 SMARCA4 ARID1A

1.08e-03416586GO:0030522
GeneOntologyBiologicalProcesscellular response to lipid

WBP2 KIF18A NCOR2 DAB2 SMARCA4 ATM ARID1A ARID5A

1.11e-03748588GO:0071396
GeneOntologyBiologicalProcesstranscription initiation at RNA polymerase I promoter

UBTFL6 SMARCA4

1.16e-0318582GO:0006361
GeneOntologyCellularComponentbBAF complex

SMARCA4 ARID1A

3.36e-0410582GO:0140092
GeneOntologyCellularComponentNLS-dependent protein nuclear import complex

KPNA5 KPNA6

3.36e-0410582GO:0042564
GeneOntologyCellularComponentnucleocytoplasmic transport complex

KPNA5 KPNA6

4.91e-0412582GO:0031074
GeneOntologyCellularComponentbeta-catenin-TCF complex

TCF7 LEF1

5.79e-0413582GO:1990907
GeneOntologyCellularComponentnpBAF complex

SMARCA4 ARID1A

6.74e-0414582GO:0071564
GeneOntologyCellularComponentclathrin-coated vesicle membrane

AP3B2 DAB2 APOB CHRM2

7.42e-04147584GO:0030665
GeneOntologyCellularComponentnBAF complex

SMARCA4 ARID1A

8.86e-0416582GO:0071565
DomainCTNNB1-bd_N

TCF7 LEF1

5.66e-054582IPR013558
DomainCTNNB1_binding

TCF7 LEF1

5.66e-054582PF08347
DomainTCF/LEF

TCF7 LEF1

5.66e-054582IPR024940
DomainArm_3

KPNA5 KPNA6

1.97e-047582PF16186
DomainImporting_su_alpha

KPNA5 KPNA6

1.97e-047582IPR024931
DomainArm_3

KPNA5 KPNA6

1.97e-047582IPR032413
DomainIBB

KPNA5 KPNA6

1.97e-047582PF01749
DomainIBB

KPNA5 KPNA6

2.62e-048582PS51214
DomainImportin-a_IBB

KPNA5 KPNA6

3.36e-049582IPR002652
DomainChromo_dom_subgr

CDY2A CDY1

4.20e-0410582IPR017984
DomainHMG_box

TCF7 UBTFL6 LEF1

5.96e-0453583PF00505
DomainARM-type_fold

KPNA5 AP3B2 KPNA6 APOB ATM ARID1A

6.26e-04339586IPR016024
DomainHMG_BOX_2

TCF7 UBTFL6 LEF1

6.30e-0454583PS50118
DomainHMG

TCF7 UBTFL6 LEF1

6.30e-0454583SM00398
Domain-

ARID1A ARID5A

9.70e-04155821.10.150.60
DomainBRIGHT

ARID1A ARID5A

9.70e-0415582SM00501
DomainARID_dom

ARID1A ARID5A

9.70e-0415582IPR001606
DomainARID

ARID1A ARID5A

9.70e-0415582PS51011
DomainARID

ARID1A ARID5A

9.70e-0415582PF01388
DomainHMG_box_dom

TCF7 UBTFL6 LEF1

1.08e-0365583IPR009071
DomainCrotonase_core_superfam

CDY2A CDY1

1.25e-0317582IPR001753
DomainECH_1

CDY2A CDY1

1.25e-0317582PF00378
DomainChromo

CDY2A CDY1

2.94e-0326582PF00385
DomainCHROMO_1

CDY2A CDY1

3.40e-0328582PS00598
DomainCHROMO_2

CDY2A CDY1

3.40e-0328582PS50013
DomainCatenin_binding_dom

TCF7 LEF1

3.65e-0329582IPR027397
Domain-

TCF7 LEF1

3.65e-03295824.10.900.10
DomainArm

KPNA5 KPNA6

4.16e-0331582PF00514
DomainChromodomain-like

CDY2A CDY1

4.43e-0332582IPR016197
DomainChromo/shadow_dom

CDY2A CDY1

4.70e-0333582IPR000953
DomainCHROMO

CDY2A CDY1

4.70e-0333582SM00298
Domain-

KPNA5 AP3B2 KPNA6 ARID1A

4.99e-032225841.25.10.10
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

TCF7 SMARCA4 LEF1

7.51e-0526453MM14793
PathwayREACTOME_RUNX3_REGULATES_WNT_SIGNALING

TCF7 LEF1

1.48e-046452MM15542
PathwayKEGG_MEDICUS_PATHOGEN_SALMONELLA_AVRA_TO_BETA_CATENIN_SIGNALING_PATHWAY

TCF7 LEF1

1.48e-046452M47736
PathwayKEGG_MEDICUS_PATHOGEN_KSHV_LANA_TO_WNT_SIGNALING_PATHWAY

TCF7 LEF1

2.07e-047452M47465
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

TCF7 SMARCA4 ARID1A LEF1

2.33e-0495454M48268
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_CELL_CYCLE_AND_PROLIFERATION

TCF7 LEF1

2.76e-048452MM17229
PathwayREACTOME_BINDING_OF_TCF_LEF_CTNNB1_TO_TARGET_GENE_PROMOTERS

TCF7 LEF1

2.76e-048452M27359
PathwayKEGG_MEDICUS_VARIANT_CDH1_REDUCED_EXPRESSION_TO_BETA_CATENIN_SIGNALING_PATHWAY

TCF7 LEF1

2.76e-048452M47413
PathwayREACTOME_RUNX3_REGULATES_WNT_SIGNALING

TCF7 LEF1

2.76e-048452M27821
PathwayKEGG_MELANOGENESIS

TCF7 CALML3 PLCB2 LEF1

2.95e-04101454M7761
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_PIGMENTATION

SMARCA4 ARID1A LEF1

3.20e-0442453M48237
PathwayWP_DNA_DAMAGE_RESPONSE_ONLY_ATM_DEPENDENT

TCF7 ATM FASLG LEF1

4.09e-04110454M39492
PathwayBIOCARTA_HSWI_SNF_PATHWAY

SMARCA4 ARID1A

4.41e-0410452MM1532
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_AXIN_TO_WNT_SIGNALING_PATHWAY

TCF7 LEF1

4.41e-0410452M47486
PathwayREACTOME_REPRESSION_OF_WNT_TARGET_GENES

TCF7 LEF1

4.41e-0410452MM15156
PathwayREACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK

GNA13 ECT2 VAV2

6.02e-0452453MM14743
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_APC_TO_WNT_SIGNALING_PATHWAY

TCF7 LEF1

6.44e-0412452M47410
PathwayBIOCARTA_HSWI_SNF_PATHWAY

SMARCA4 ARID1A

6.44e-0412452M22006
PathwayWP_HEPATITIS_C_AND_HEPATOCELLULAR_CARCINOMA

FASLG LEF1 VAV2

7.49e-0456453M39413
PathwayREACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK

GNA13 ECT2 VAV2

8.72e-0459453M11215
PathwayREACTOME_REPRESSION_OF_WNT_TARGET_GENES

TCF7 LEF1

8.85e-0414452M27402
PathwayREACTOME_FORMATION_OF_AXIAL_MESODERM

TCF7 LEF1

8.85e-0414452M46441
PathwayREACTOME_MITF_M_REGULATED_MELANOCYTE_DEVELOPMENT

TCF7 SMARCA4 ARID1A LEF1

9.34e-04137454M48232
PathwayREACTOME_CA2_PATHWAY

TCF7 PLCB2 LEF1

1.01e-0362453M27321
PathwayPID_THROMBIN_PAR4_PATHWAY

GNA13 PLCB2

1.02e-0315452M138
PathwayWP_CANCER_PATHWAYS

TCF7 CALML3 GNA13 PLCB2 FASLG LEF1 HSP90AB1

1.03e-03507457M48302
PathwayREACTOME_DEATH_RECEPTOR_SIGNALING

GNA13 FASLG ECT2 VAV2

1.07e-03142454MM15431
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

TCF7 LEF1

1.16e-0316452MM17241
PathwayBIOCARTA_P53_PATHWAY

TIMP3 ATM

1.16e-0316452M14863
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_CELL_CYCLE_AND_PROLIFERATION

TCF7 LEF1

1.31e-0317452M48240
PathwayREACTOME_GERM_LAYER_FORMATION_AT_GASTRULATION

TCF7 LEF1

1.31e-0317452M45017
PathwayWP_AMPLIFICATION_AND_EXPANSION_OF_ONCOGENIC_PATHWAYS_AS_METASTATIC_TRAITS

TCF7 LEF1

1.31e-0317452M39443
PathwayREACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE

GNA13 ECT2 VAV2

1.43e-0370453MM14824
PathwayREACTOME_DEATH_RECEPTOR_SIGNALING

GNA13 FASLG ECT2 VAV2

1.44e-03154454M27697
Pubmed

PRDM paralogs antagonistically balance Wnt/β-catenin activity during craniofacial chondrocyte differentiation.

TCF7 SMARCA4 LEF1

1.01e-061259335132438
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

WBP2 PDE2A WASHC4 AKAP17A SMARCA4 KPNA6 ATM RAPGEF2 ARID1A CRTAP HSP90AB1 MICU1

1.38e-061285591235914814
Pubmed

Cell-autonomous requirement for TCF1 and LEF1 in the development of Natural Killer T cells.

TCF7 LEF1

2.83e-06259226490636
Pubmed

Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo.

TCF7 LEF1

2.83e-06259216424171
Pubmed

Hematopoietic and Leukemic Stem Cells Have Distinct Dependence on Tcf1 and Lef1 Transcription Factors.

TCF7 LEF1

2.83e-06259227044748
Pubmed

Differential expression of the HMG box factors TCF-1 and LEF-1 during murine embryogenesis.

TCF7 LEF1

2.83e-0625928223271
Pubmed

Tumor progression by epithelial-mesenchymal transition in ARID1A- and SMARCA4-aberrant solid-type poorly differentiated gastric adenocarcinoma.

SMARCA4 ARID1A

2.83e-06259234997313
Pubmed

Expression of LEF1 and TCF1 (TCF7) proteins associates with clinical progression of nasopharyngeal carcinoma.

TCF7 LEF1

2.83e-06259230918012
Pubmed

TCF7 and LEF-1 downregulation in sepsis promotes immune suppression by inhibiting CD4+ T cell proliferation.

TCF7 LEF1

2.83e-06259237741305
Pubmed

Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1.

TCF7 LEF1

2.83e-0625929462507
Pubmed

Downregulation of TCF7 and LEF1 is a key determinant of tumor-infiltrating regulatory T-cell function.

TCF7 LEF1

2.83e-06259238169425
Pubmed

Tcf1 and Lef1 provide constant supervision to mature CD8+ T cell identity and function by organizing genomic architecture.

TCF7 LEF1

2.83e-06259234615872
Pubmed

Mass spectrometric analysis of the phosphorylation levels of the SWI/SNF chromatin remodeling/tumor suppressor proteins ARID1A and Brg1 in ovarian clear cell adenocarcinoma cell lines.

SMARCA4 ARID1A

2.83e-06259225083560
Pubmed

Cell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentials.

TCF7 LEF1

2.83e-06259222111711
Pubmed

Coffin-Siris syndrome in two chinese patients with novel pathogenic variants of ARID1A and SMARCA4.

SMARCA4 ARID1A

2.83e-06259235353340
Pubmed

Clinicopathological and prognostic significance of SWI/SNF complex subunits in undifferentiated gastric carcinoma.

SMARCA4 ARID1A

8.48e-06359236464671
Pubmed

The pro-osteogenic action of beta-catenin requires interaction with BMP signaling, but not Tcf/Lef transcriptional activity.

TCF7 LEF1

8.48e-06359218247340
Pubmed

Beta-catenin/LEF1 activated enamelin expression in ameloblast-like cells.

ENAM LEF1

8.48e-06359220599763
Pubmed

Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box.

TCF7 LEF1

8.48e-0635921989880
Pubmed

Age-related decline in the expression of BRG1, ATM and ATR are partially reversed by dietary restriction in the livers of female mice.

SMARCA4 ATM

8.48e-06359238970714
Pubmed

Differential expression of LEF1/TCFs family members in colonic carcinogenesis.

TCF7 LEF1

8.48e-06359227433921
Pubmed

Redundant functions of TCF-1 and LEF-1 during T and NK cell development, but unique role of TCF-1 for Ly49 NK cell receptor acquisition.

TCF7 LEF1

8.48e-06359212731066
Pubmed

Cutting edge: generation of memory precursors and functional memory CD8+ T cells depends on T cell factor-1 and lymphoid enhancer-binding factor-1.

TCF7 LEF1

8.48e-06359222875805
Pubmed

Selectivity of chromatin-remodelling cofactors for ligand-activated transcription.

SMARCA4 ARID1A

8.48e-06359211780067
Pubmed

SWI/SNF inactivation in the endometrial epithelium leads to loss of epithelial integrity.

SMARCA4 ARID1A

8.48e-06359233075803
Pubmed

TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases.

TCF7 LEF1

8.48e-06359231216480
Pubmed

Immature thymocytes undergoing receptor rearrangements are resistant to an Atm-dependent death pathway activated in mature T cells by double-stranded DNA breaks.

ATM FASLG

8.48e-06359210993919
Pubmed

Tcf1 and Lef1 transcription factors establish CD8(+) T cell identity through intrinsic HDAC activity.

TCF7 LEF1

8.48e-06359227111144
Pubmed

Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome.

SMARCA4 ARID1A

8.48e-06359222426308
Pubmed

ARID1A, BRG1, and INI1 deficiency in undifferentiated and dedifferentiated endometrial carcinoma: a clinicopathologic, immunohistochemical, and next-generation sequencing analysis of a case series from a single institution.

SMARCA4 ARID1A

8.48e-06359236252860
Pubmed

Ataxia telangiectasia mutated in cardiac fibroblasts regulates doxorubicin-induced cardiotoxicity.

ATM FASLG

8.48e-06359226862121
Pubmed

ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers.

SMARCA4 ARID1A

8.48e-06359221900401
Pubmed

ATM-mediated phosphorylation of the chromatin remodeling enzyme BRG1 modulates DNA double-strand break repair.

SMARCA4 ATM

8.48e-06359224413084
Pubmed

Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation.

SMARCA4 ARID1A LEF1

1.47e-052859330037996
Pubmed

Association between Apo B, LDL-R and PCSK9 gene polymorphisms with coronary artery diseases in Egyptians.

SMARCA4 APOB

1.69e-05459238874786
Pubmed

Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma.

SMARCA4 ARID1A

1.69e-05459231906887
Pubmed

TCF transcription factors: molecular switches in carcinogenesis.

TCF7 LEF1

1.69e-05459210528152
Pubmed

SWI/SNF protein component BAF250a regulates cardiac progenitor cell differentiation by modulating chromatin accessibility during second heart field development.

SMARCA4 ARID1A

1.69e-05459222621927
Pubmed

LEF-1 negatively controls interleukin-4 expression through a proximal promoter regulatory element.

TCF7 LEF1

1.69e-05459218579517
Pubmed

Pja2 Inhibits Wnt/β-catenin Signaling by Reducing the Level of TCF/LEF1.

TCF7 LEF1

1.69e-05459230021253
Pubmed

The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers.

SMARCA4 ARID1A

1.69e-05459228262751
Pubmed

The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy.

TCF7 LEF1

1.69e-05459223103132
Pubmed

Hsp90 interactions and acylation target the G protein Galpha 12 but not Galpha 13 to lipid rafts.

GNA13 HSP90AB1

1.69e-05459212117999
Pubmed

MiR-21 down-regulation suppresses cell growth, invasion and induces cell apoptosis by targeting FASL, TIMP3, and RECK genes in esophageal carcinoma.

TIMP3 FASLG

1.69e-05459223504349
Pubmed

A long-range restriction map of deletion interval 6 of the human Y chromosome: a region frequently deleted in azoospermic males.

CDY2A CDY1

1.69e-0545929806824
Pubmed

Cloning of two novel human importin-alpha subunits and analysis of the expression pattern of the importin-alpha protein family.

KPNA5 KPNA6

1.69e-0545929395085
Pubmed

Expression of secreted frizzled-related protein 1 and 3, T-cell factor 1 and lymphoid enhancer factor 1 in clear cell renal cell carcinoma.

TCF7 LEF1

1.69e-05459223572277
Pubmed

Undifferentiated Endometrial Carcinomas Show Frequent Loss of Core Switch/Sucrose Nonfermentable Complex Proteins.

SMARCA4 ARID1A

1.69e-05459228863077
Pubmed

Heterozygous mutation of ataxia-telangiectasia mutated gene aggravates hypercholesterolemia in apoE-deficient mice.

APOB ATM

1.69e-05459215863839
Pubmed

LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6.

TCF7 LEF1

1.69e-05459226214741
Pubmed

Tcf1 and Lef1 are required for the immunosuppressive function of regulatory T cells.

TCF7 LEF1

1.69e-05459230837262
Pubmed

LSM12 facilitates the progression of colorectal cancer by activating the WNT/CTNNB1 signaling pathway.

TCF7 LEF1

1.69e-05459237303493
Pubmed

Mapping canonical Wnt signaling in the developing and adult retina.

TCF7 LEF1

1.69e-05459217065530
Pubmed

Two related ARID family proteins are alternative subunits of human SWI/SNF complexes.

SMARCA4 ARID1A

1.69e-05459215170388
Pubmed

Cloning and characterization of hELD/OSA1, a novel BRG1 interacting protein.

SMARCA4 ARID1A

1.69e-05459211988099
Pubmed

Regulation of ATM and ATR by SMARCAL1 and BRG1.

SMARCA4 ATM

1.69e-05459230317028
Pubmed

Activity-dependent neuroprotective protein constitutes a novel element in the SWI/SNF chromatin remodeling complex.

SMARCA4 ARID1A

1.69e-05459217878164
Pubmed

The clinicopathological significance of SWI/SNF alterations in gastric cancer is associated with the molecular subtypes.

SMARCA4 ARID1A

1.69e-05459233481850
Pubmed

Identification and characterization of the cynomolgus monkey chromodomain gene cynCDY, an orthologue of the human CDY gene family.

CDY2A CDY1

1.69e-05459212149400
Pubmed

ATM binds to beta-adaptin in cytoplasmic vesicles.

AP3B2 ATM

1.69e-0545929707615
Pubmed

Genotype-phenotype correlation of Coffin-Siris syndrome caused by mutations in SMARCB1, SMARCA4, SMARCE1, and ARID1A.

SMARCA4 ARID1A

1.69e-05459225168959
Pubmed

The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.

NCOR2 TCF7 SMARCA4 LEF1 HSP90AB1

1.87e-0519159524146773
Pubmed

Genetic associations of brain structural networks in schizophrenia: a preliminary study.

APOL5 APOB CHRM2

2.02e-053159320691427
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SCN11A DENND4A NOP14 GNA13 PKHD1 PALM APOB RAB1B ATM ARID1A HSP90AB1

2.68e-051442591135575683
Pubmed

Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2.

TCF7 LEF1

2.82e-05559221285352
Pubmed

Rescue of a Wnt mutation by an activated form of LEF-1: regulation of maintenance but not initiation of Brachyury expression.

TCF7 LEF1

2.82e-05559211447280
Pubmed

Prostaglandin E1 and Its Analog Misoprostol Inhibit Human CML Stem Cell Self-Renewal via EP4 Receptor Activation and Repression of AP-1.

TCF7 LEF1

2.82e-05559228844837
Pubmed

The HSA domain of BRG1 mediates critical interactions required for glucocorticoid receptor-dependent transcriptional activation in vivo.

SMARCA4 ARID1A

2.82e-05559218086889
Pubmed

p300/CREB binding protein-related protein p270 is a component of mammalian SWI/SNF complexes.

SMARCA4 ARID1A

2.82e-0555929584200
Pubmed

Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors.

SMARCA4 ARID1A

2.82e-05559212200431
Pubmed

Systematic In Vivo Inactivation of Chromatin-Regulating Enzymes Identifies Setd2 as a Potent Tumor Suppressor in Lung Adenocarcinoma.

SMARCA4 ARID1A

2.82e-05559228202515
Pubmed

Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association.

KPNA5 ATM

2.82e-05559215929992
Pubmed

Retroposition of autosomal mRNA yielded testis-specific gene family on human Y chromosome.

CDY2A CDY1

2.82e-05559210192397
Pubmed

The Chromatin Regulator Mll1 Supports T Follicular Helper Cell Differentiation by Controlling Expression of Bcl6, LEF-1, and TCF-1.

TCF7 LEF1

2.82e-05559237074193
Pubmed

Plasmodium circumsporozoite protein promotes the development of the liver stages of the parasite.

KPNA5 KPNA6

2.82e-05559217981117
Pubmed

The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation.

SMARCA4 ARID1A LEF1

2.92e-053559332504627
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

AKAP17A RBBP6 DAB2 SMARCA4 APOB RAB1B ECT2 NKRF HSP90AB1

2.99e-0594959936574265
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

KPNA5 KIF18A NOP14 SMARCA4 NKRF

3.83e-0522259537071664
Pubmed

Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import.

KPNA5 KPNA6

4.23e-0565928551560
Pubmed

Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex.

SMARCA4 ARID1A

4.23e-05659216940996
Pubmed

HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator.

KPNA5 KPNA6

4.23e-0565927859280
Pubmed

Nuclear localization signal of HIV-1 as a novel target for therapeutic intervention.

KPNA5 KPNA6

4.23e-0565928529100
Pubmed

Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression.

TCF7 LEF1

4.23e-05659229337183
Pubmed

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse.

TCF7 LEF1

4.23e-0565929488439
Pubmed

Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain.

TCF7 LEF1

4.23e-05659223152144
Pubmed

SLUG: a new target of lymphoid enhancer factor-1 in human osteoblasts.

TCF7 LEF1

4.23e-05659220128911
Pubmed

Phosphorylation of residue 131 of HIV-1 matrix is not required for macrophage infection.

KPNA5 KPNA6

4.23e-0565929008157
Pubmed

The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest.

SMARCA4 ARID1A

4.23e-05659216230384
Pubmed

Numerous BAF complex genes are mutated in Coffin-Siris syndrome.

SMARCA4 ARID1A

4.23e-05659225081545
Pubmed

Thymine DNA glycosylase promotes transactivation of β-catenin/TCFs by cooperating with CBP.

TCF7 LEF1

4.23e-05659224748645
Pubmed

p17 and p17-containing gag precursors of input human immunodeficiency virus are transported into the nuclei of infected cells.

KPNA5 KPNA6

4.23e-0565922064827
Pubmed

A synthetic peptide bearing the HIV-1 integrase 161-173 amino acid residues mediates active nuclear import and binding to importin alpha: characterization of a functional nuclear localization signal.

KPNA5 KPNA6

4.23e-05659215037073
Pubmed

Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation.

KPNA5 KPNA6

4.23e-0565928876228
Pubmed

Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infection.

KPNA5 KPNA6

4.23e-0565927745752
Pubmed

ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice.

SMARCA4 ARID1A

4.23e-05659229604291
Pubmed

γ-Catenin-Dependent Signals Maintain BCR-ABL1+ B Cell Acute Lymphoblastic Leukemia.

TCF7 LEF1

4.23e-05659230991025
Pubmed

Backbone cyclic peptide, which mimics the nuclear localization signal of human immunodeficiency virus type 1 matrix protein, inhibits nuclear import and virus production in nondividing cells.

KPNA5 KPNA6

4.23e-0565929548947
Pubmed

Evidence for direct association of Vpr and matrix protein p17 within the HIV-1 virion.

KPNA5 KPNA6

4.23e-0565928659115
Pubmed

TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4(+) T cell fate and interact with Runx3 to silence Cd4 in CD8(+) T cells.

TCF7 LEF1

4.23e-05659224836425
Pubmed

The putative alpha helix 2 of human immunodeficiency virus type 1 Vpr contains a determinant which is responsible for the nuclear translocation of proviral DNA in growth-arrested cells.

KPNA5 KPNA6

4.23e-0565929557700
GeneFamilyAT-rich interaction domain containing

ARID1A ARID5A

3.76e-0415352418
GeneFamilyArmadillo repeat containing|Importins

KPNA5 KPNA6

5.46e-0418352596
GeneFamilyApolipoproteins

APOL5 APOB

7.47e-0421352405
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

NPR3 DENND4A

1.06e-0325352504
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

KPNA5 KPNA6

3.13e-0343352409
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ECT2 VAV2

7.23e-0366352722
GeneFamilyEF-hand domain containing

CABP5 CALML3 MICU1

8.62e-03219353863
CoexpressionGSE5099_DAY3_VS_DAY7_MCSF_TREATED_MACROPHAGE_DN

TCF7 GNA13 ARID1A ECT2 LEF1 CDY1

3.30e-06184586M6593
CoexpressionGSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_UP

PPP1R3A TIMP3 ACTR5 DAB2 LEF1 VAV2

5.03e-06198586M5302
CoexpressionGSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN

TCF7 NOP14 CALML3 RAPGEF2 MICU1

2.81e-05160585M338
ToppCellsystemic_lupus_erythematosus-managed-Hematopoietic-Progen-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NPR3 TCF7 TIMP3 LEF1 RGS1 HDC

2.12e-07196586768fce92bcf47734fa6c4a448f1266f34583fb41
ToppCellsystemic_lupus_erythematosus-managed-Hematopoietic-Progen|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NPR3 TCF7 TIMP3 LEF1 RGS1 HDC

2.19e-071975864c928a4dde295bf220bcb0b2f30ca4a106b0e511
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 ETAA1 FASLG LEF1 RGS1

2.17e-061615858e787cc7f5e818cad1a6ed143a5fe310993e030b
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-CD8+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 ETAA1 FASLG LEF1 RGS1

2.17e-06161585ca9233370490e27b9a1892669d6b82db2136180e
ToppCellASK428-Immune-Mast_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

TIMP3 ETAA1 NAV1 RGS1 HDC

2.67e-06168585c399fcb4d1d0be48026c2ecabc34a5935e7adf73
ToppCellfacs-MAT-Fat-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TCF7 FASLG LEF1 ARID5A

2.75e-061695853a18b4ad826e6ab9cbfd1d51a23a1b67c9a08596
ToppCellURO-Lymphocyte-B-Plasmablast|URO / Disease, Lineage and Cell Type

ENAM KIF18A ECT2 RGS1 HDC

3.00e-0617258548888ef50ac784b38aca81da68f8a94ce09c670d
ToppCellfacs-BAT-Fat-18m-Lymphocytic-T_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1 ARID5A

3.26e-06175585bf1ef77d5fed2135ac83a4f7e445ab59d1538696
ToppCellfacs-Kidney-nan-18m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A TCF7 FASLG LEF1 RGS1

3.26e-0617558584d91843b34504636d5af6bda9930031409a1627
ToppCellfacs-Kidney-nan-18m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A TCF7 FASLG LEF1 RGS1

3.26e-061755852368aa8318ab83e0e0fd539a17264f9e1d755cf1
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE2A TCF7 FASLG LEF1 RGS1

3.45e-06177585d6b7d387e7485ff52ce27f51df8b8050f49fd941
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN11A TCF7 ECT2 LEF1 ARID5A

3.74e-061805858cef63866c205df3825df84ce51fa61aa04ae491
ToppCellfacs-MAT-Fat-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1 ARID5A

3.84e-061815856bb4b19f7804319dd7cfa450c7d1c7b4e90f2450
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TIMP3 DAB2 CRTAP HDC

3.84e-06181585a53f05c4c47465ee62e353716456bd09ab464b23
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1 ARID5A

4.06e-0618358586c67f258fa25a818797df5d4df7f27b44cb5381
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMP3 DAB2 APOB ALDH6A1 HDC

4.16e-061845853d7dd193a0826cc7a4e454a29236a16c315e5965
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMP3 DAB2 APOB ALDH6A1 HDC

4.16e-0618458545577ff91c3b2b303acd97239dde2463ea7a429c
ToppCellsystemic_lupus_erythematosus-managed-Hematopoietic-Progen-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NPR3 TCF7 TIMP3 LEF1 HDC

4.28e-06185585a139e95d31af9866ed2d4618ad67557851b98ef3
ToppCelldroplet-Liver-Npc-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A PDE2A TIMP3 TMEM87A CRTAP

4.39e-0618658575258d88e23112fd1f0f7c71ef0366abb400d33e
ToppCellsystemic_lupus_erythematosus-flare-Hematopoietic|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NPR3 TCF7 ATM LEF1 HDC

4.62e-0618858588b808561ebde997ac8a8bbd1d9bbda49bbb6646
ToppCellfacs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CABP5 TIMP3 DAB2 PALM

4.99e-0619158548823a97c38263f2c6e58348214f5b62773a6368
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CABP5 TIMP3 DAB2 PALM

4.99e-061915850eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A PDE2A TIMP3 NAV1 HDC

5.25e-06193585826b8dd801298b3e0cd76232feae5a14026b8806
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A PDE2A TIMP3 NAV1 HDC

5.25e-0619358587d3a577d37fb0cb4b6313c596310de452bc3872
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF7 ACVR1C LEF1 ARID5A HSP90AB1

5.25e-061935854e78ddc96d8e403a21c4a303b1f26512d2ac91e8
ToppCellsystemic_lupus_erythematosus-managed-Hematopoietic|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NPR3 TCF7 TIMP3 LEF1 HDC

5.66e-06196585a6fcd4f9a39f8e4ff3076735dd615311104dfd1d
ToppCellnormal-na-Hematopoietic|normal / PBMC cell types (v2) per disease, treatment status, and sex

NPR3 TCF7 TIMP3 LEF1 HDC

5.66e-06196585c2c1c894706428bad5bfc81e9ae0f921ab1286d3
ToppCellnormal-na-Hematopoietic-Progen-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

NPR3 TCF7 TIMP3 LEF1 HDC

5.81e-061975858c4bda1842ff8bd808517c2aa179ac7596d1923d
ToppCellnormal-na-Hematopoietic-Progen|normal / PBMC cell types (v2) per disease, treatment status, and sex

NPR3 TCF7 TIMP3 LEF1 HDC

5.81e-0619758514de3db0b36412e801472a6c1502686ae7be9faa
ToppCelllymphoid|World / Lineage, cell class and subclass

TCF7 ATM LEF1 RGS1 HSP90AB1

6.10e-06199585bf599721e7109cf9f361e9381544c291920c28be
ToppCellmild-CD4+_T_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TCF7 ATM ACVR1C LEF1 HSP90AB1

6.10e-061995853e4baaf4ee23f257d821194468102c00a8ad2f21
ToppCellSepsis-URO-Lymphocyte-B-Plasmablast|URO / Disease, condition lineage and cell class

ENAM KIF18A ECT2 RGS1 HDC

6.10e-061995850df6cafb7f3b607cbe80b6f25b4fd62d421d01ee
ToppCell(1)_T_cell-(16)_Tfh|(1)_T_cell / shred on Cell_type and subtype

TCF7 DENND10 ATM LEF1 ARID5A

6.25e-062005853b28137e8e69b98fde9f6ab8320cb4d1c3543ef9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TIMP3 NAV1 ECT2 LEF1

4.85e-05154584e51a5114f0ec38f997f5b8bbf3a7770f98595474
ToppCelldroplet-Lung-nan-3m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TCF7 FASLG LEF1

5.23e-05157584b337937a88f62030114a28d70a63168417672767
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-CD8+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

5.49e-05159584776139481f2d3630461b4dabca606ebf6e6f034e
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

5.49e-05159584bbb19e2f0b7cee70836fa96dc22f888cbc403d28
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 CALML3 PKHD1 FASLG

5.63e-051605848590281165eab6514a9f6a022b900d4c222c1044
ToppCellPND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A TIMP3 DAB2 PALM

5.77e-05161584133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A TIMP3 DAB2 PALM

5.77e-051615849466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN11A TCF7 RAPGEF2 FASLG

5.77e-05161584334f540dff3508d451e5e85e8e4e8f3b8d6b74e7
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A TIMP3 DAB2 PALM

5.77e-05161584cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN11A TCF7 RAPGEF2 FASLG

5.77e-0516158481d44438e4be4e68a59247e62f02026301a8a0c5
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A TIMP3 DAB2 PALM

5.91e-0516258496c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NAV1 CHRM2 RGS1 HDC

6.19e-051645842c48c6e4eeee845f0563982d0bfa2a176ca5ef61
ToppCelldroplet-Limb_Muscle-nan-3m-Myeloid-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB2 RAPGEF2 RGS1 HDC

6.49e-051665840a7992bc673fca546636563ec3fc17a4298ab6b1
ToppCellfacs-Heart-RV-3m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

6.49e-05166584c0fd3f3f5c3412746da279b856af0d28b9b70c5d
ToppCellfacs-Heart-RV-3m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

6.49e-0516658433c4876df43b4c1d100699bca47459918bd054d6
ToppCellfacs-Heart-RV-3m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

6.49e-05166584ac9b9df57d65ccbbf9ae3add50c5663efcd30dcb
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCF7 ETAA1 FASLG RGS1

6.64e-0516758438b1f052d663fa8f407c54bdd2060216f26feb0e
ToppCellfacs-Heart-LA-3m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

6.80e-0516858416c3313c4186fa327d71215f8eebc31fc12ff1c0
ToppCellfacs-Heart-LA-3m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

6.80e-0516858424d1e0a05cda09ee3b80208d75cb2b601023f3bf
ToppCellfacs-BAT-Fat-24m-Lymphocytic-T_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

6.80e-05168584e268e9ee43a2cbf6153bcdf1e6e7674090ee2e6c
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 ACTR5 ETAA1 FASLG

6.80e-05168584182f08106ac65ea501e2fb9139d3b44b7c4662c9
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

6.80e-0516858468ef5d1043fca804032669bf990edf110d65cf63
ToppCellfacs-Heart-LA-3m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

6.80e-05168584b952af95a68888adedd03b1b60836d18524611ab
ToppCellEndothelial-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

PDE2A TIMP3 PALM RNASE13

6.96e-0516958495c617143e1fbdd1d55a93ffdcc210e0be37cf2f
ToppCellEndothelial-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

PDE2A TIMP3 PALM APOB

6.96e-051695848889c9e8af1ab0b093d57b69abd80b59b3461be9
ToppCellfacs-Heart-LV-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

7.12e-0517058471e5e27c3c4e6cc8dc9b063bd51c21c049f54416
ToppCellfacs-Heart-LV-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

7.12e-05170584255bbbd00d0e17510c5a8c5faa43ed90d887a9de
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCF7 FASLG LEF1 RGS1

7.12e-05170584282afbbea5c88d973cf44727c473a3615f0f02a3
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCF7 FASLG LEF1 RGS1

7.12e-05170584f9596088a1a7686467e54eabaad5269f2c5fbfec
ToppCellsystemic_lupus_erythematosus-treated-Hematopoietic|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NPR3 TCF7 ATM LEF1

7.12e-051705849a18756e6721980d4b6c37bb52ddfe93ca79c5ab
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

7.12e-051705847040f7b1e4d8d26db787449e557371c5d872c95a
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-TRGV4_gdT|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPR3 ACTR5 RGS1 ARID5A

7.12e-0517058465c7ed586e7615203a59999549892ed466a89502
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE2A TCF7 FASLG LEF1

7.12e-051705848e9b5f7bfb61f8d84d0b17fb0c191da4dabad63d
ToppCellMyeloid-Myeloid-D_(Mast_cell)|Myeloid / shred on cell class and cell subclass (v4)

RGS1 DISP1 CRTAP HDC

7.28e-051715845f1aafc4c55a9c6c3153430186a8a351425a3cb9
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

DENND4A TCF7 APOB ATM

7.28e-051715842e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellControl-Myeloid-Mast|World / Disease state, Lineage and Cell class

DENND4A RAPGEF2 RGS1 HDC

7.28e-05171584ed8e61d524f4cddc6084b261175df54d2a64a60f
ToppCellfacs-GAT-Fat-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 ARID5A

7.45e-05172584a9f0ccaca0d83bfec79e3251e346a165c34c242b
ToppCellEndothelial-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

SCN11A PDE2A TIMP3 PALM

7.45e-05172584d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

7.45e-05172584f320813177f246926bfd5862b4e0f9bd828cebab
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

7.45e-05172584b3c12a4bb08ce931de6fe800b605f3e43adea0b5
ToppCellnormal-na-Hematopoietic-Progen-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

TCF7 TIMP3 ATM LEF1

7.62e-05173584e666364eb110c1c976e5b09a632dd1454513f131
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A DAB2 FASLG RGS1

7.62e-051735847456a417c5c1d4ba25f9489065aae322421308a6
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A DAB2 FASLG RGS1

7.62e-0517358435586a9e5f15b41609b6224e33eb3aa3cb7e03b7
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A DAB2 FASLG RGS1

7.62e-05173584cd635751f999e12b14c0accfa1c4c1fd3c1d4540
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-CD8+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

7.79e-05174584986e591d3d46009e53548dfa1f2126cf31063ef4
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

7.79e-05174584785be49a2dbbb1dff0fbced1b48b942c2f4a508d
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCF7 FASLG LEF1 RGS1

7.79e-051745847c8cc5c2872fc7bcca7ebddaf5a6f20e617a2674
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

7.96e-05175584b66731573e79576fbf17538059cb8243dd4903c4
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

7.96e-05175584392123b037ff48c924ebd020ac86891116a2dcd3
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

7.96e-051755845f18077e5c3edc6a2708315db53683afa4a6d4a8
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TCF7 FASLG LEF1

7.96e-05175584a72c6ceca5ddbd34f652e7302defefa2d105e17e
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD8+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TCF7 FASLG LEF1

7.96e-051755849a462e9e6f7bbb64abb09ad6c080df3576073540
ToppCelldroplet-Pancreas-PANCREAS-30m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TCF7 FASLG RGS1

7.96e-05175584ca2eabf03b70353e7eb15b6f622b2f9223a99e18
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE2A TCF7 FASLG LEF1

7.96e-05175584f949613ee45f5d950578c512d197716855118d18
ToppCellfacs-Trachea-nan-18m-Lymphocytic-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

8.14e-0517658414c6c3fdb53f9dfc02b951bc955b90213110c089
ToppCellControl-Myeloid-Mast|Myeloid / Disease state, Lineage and Cell class

DENND4A TIMP3 RGS1 HDC

8.14e-051765840c5916d63e1ada09105e46d2429b75129b7329ec
ToppCellfacs-Trachea-nan-18m-Lymphocytic|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

8.14e-051765849dd862dcee6947a53189728f6b4cd40e7b67cb71
ToppCellfacs-GAT-Fat-3m-Lymphocytic|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A TCF7 FASLG LEF1

8.14e-051765842e3f25a338842384517656d05776a52cbfc62b52
ToppCellfacs-GAT-Fat-3m-Lymphocytic-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A TCF7 FASLG LEF1

8.14e-051765840823088bc6b19c7ad784d83c2ccdfae80611afab
ToppCellfacs-Trachea-nan-18m-Lymphocytic-T_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

8.14e-05176584d990e7af8120210100d13caa0465b27cf77a451a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KPNA5 TCF7 APOB LEF1

8.32e-0517758464b8f665fdaf975558af2ad7d9b54d206de8350c
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE2A NPR3 LEF1 CHRM2

8.32e-051775841921226196b2ab7919d9f843e60d9f4bd9ec9c57
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-mature_NK_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TCF7 FASLG LEF1

8.32e-05177584dba8b30a311051c22ca5f77697f5dbf9423c3ba0
ToppCellSevere-CD4+_T_activated|Severe / Disease group and Cell class

PALM RGS1 ARID5A HSP90AB1

8.32e-05177584a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-mature_NK_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7 FASLG LEF1 RGS1

8.32e-0517758493379bfd7484812bb45aa27c0324a75be9641685
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-mature_NK_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TCF7 FASLG RGS1

8.32e-051775846561794ae3b14b5279b249eb5e93b80ef15ed82c
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_naive-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TCF7 ATM LEF1 HSP90AB1

8.32e-05177584db6de487ef7976b444afadbf3ac60b3259925566
DrugLidocaone hydrochloride [73-78-9]; Down 200; 14.8uM; MCF7; HT_HG-U133A

NPR3 TCF7 TIMP3 CALML3 ATM VAV2

8.81e-061905864421_DN
DrugCephalothin sodium salt [58-71-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A

TCF7 ETAA1 ATM RAPGEF2 ALDH6A1 VAV2

1.08e-051975866819_DN
DrugLevodopa [59-92-7]; Up 200; 20.2uM; PC3; HT_HG-U133A

KPNA5 SCN11A CALML3 PALM LEF1 RGS1

1.15e-051995864571_UP
DiseaseBurkitt Leukemia

GNA13 SMARCA4 ARID1A

2.90e-0615563C4721444
DiseaseAfrican Burkitt's lymphoma

GNA13 SMARCA4 ARID1A

2.90e-0615563C0343640
Diseaseintrahepatic cholangiocarcinoma (is_marker_for)

ARID1A FASLG HSP90AB1

6.14e-0619563DOID:4928 (is_marker_for)
Diseasecancer (implicated_via_orthology)

RBBP6 CALML3 SMARCA4 ATM ARID1A HSP90AB1

1.18e-05268566DOID:162 (implicated_via_orthology)
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

SMARCA4 ARID1A

3.52e-055562C3281201
DiseaseBurkitt Lymphoma

GNA13 SMARCA4 ARID1A

4.42e-0536563C0006413
Diseaseesterified cholesterol measurement, intermediate density lipoprotein measurement

SMARCA4 APOB

9.83e-058562EFO_0008589, EFO_0008595
Diseasemultiple sclerosis

NCOR2 TCF7 SMARCA4 LEF1 RGS1 VAV2 CRTAP

1.28e-04594567MONDO_0005301
Diseasetriglycerides to total lipids in large HDL percentage

NCOR2 APOB ARID1A

2.05e-0460563EFO_0022330
Diseaseprostate cancer (is_marker_for)

TCF7 TIMP3 SMARCA4 LEF1

2.23e-04156564DOID:10283 (is_marker_for)
DiseaseCoffin-Siris syndrome

SMARCA4 ARID1A

2.72e-0413562C0265338
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

NCOR2 NPR3 SMARCA4 APOB ARID1A

2.75e-04303565EFO_0004612, EFO_0020945
Diseaseesterified cholesterol measurement, low density lipoprotein cholesterol measurement

SMARCA4 APOB

3.17e-0414562EFO_0004611, EFO_0008589
DiseaseSpermatogenic Failure, Nonobstructive, Y-Linked

CDY2A CDY1

4.17e-0416562C1839071
DiseaseSPERMATOGENIC FAILURE, Y-LINKED, 2

CDY2A CDY1

4.17e-0416562415000
DiseaseSpermatogenic failure, Y-linked, 2

CDY2A CDY1

4.17e-0416562cv:C1839071
Diseasevery low density lipoprotein cholesterol measurement, esterified cholesterol measurement

SMARCA4 APOB

5.31e-0418562EFO_0008317, EFO_0008589
DiseaseHereditary Non-Polyposis Colon Cancer Type 2

SMARCA4 ATM

5.93e-0419562C1333991
Diseasesodium-coupled monocarboxylate transporter 1 measurement

SMARCA4 APOB

5.93e-0419562EFO_0802076
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

SMARCA4 ATM

5.93e-0419562C2936783
Diseasecholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage

SMARCA4 APOB

7.26e-0421562EFO_0022246
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

NCOR2 SMARCA4 APOB ARID1A

7.48e-04215564EFO_0008317, EFO_0008591
DiseaseGranulomatous Slack Skin

ATM ARID1A

7.98e-0422562C0376407
Diseasevery low density lipoprotein cholesterol measurement, lipid measurement

NCOR2 SMARCA4 APOB ARID1A

8.15e-04220564EFO_0004529, EFO_0008317
Diseasetotal cholesterol measurement, very low density lipoprotein cholesterol measurement

NCOR2 SMARCA4 APOB ARID1A

8.72e-04224564EFO_0004574, EFO_0008317
DiseaseLymphoma, T-Cell, Cutaneous

ATM ARID1A

8.72e-0423562C0079773
Diseasecholesteryl ester measurement, very low density lipoprotein cholesterol measurement

NCOR2 SMARCA4 APOB ARID1A

8.86e-04225564EFO_0008317, EFO_0010351
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

SMARCA4 APOB ARID1A

8.93e-0499563EFO_0004611, EFO_0007878
DiseaseMalignant neoplasm of breast

KPNA5 PPP1R3A PDE2A ATM TRAPPC8 ARID1A ECT2 LEF1

9.04e-041074568C0006142
Diseasevery low density lipoprotein cholesterol measurement, phospholipid measurement

NCOR2 SMARCA4 APOB ARID1A

9.46e-04229564EFO_0004639, EFO_0008317
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

SMARCA4 APOB ARID1A

9.73e-04102563EFO_0004329, EFO_0004611
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

SMARCA4 APOB ARID1A

1.00e-03103563EFO_0008595, EFO_0020944
Diseasefamilial hyperlipidemia

SMARCA4 APOB ARID1A

1.09e-03106563MONDO_0001336
Diseaselevel of Sterol ester (27:1/18:2) in blood serum

SMARCA4 APOB

1.12e-0326562OBA_2045194
Diseaselevel of Sterol ester (27:1/16:0) in blood serum

SMARCA4 APOB

1.12e-0326562OBA_2045191
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

SMARCA4 ATM

1.12e-0326562C0009405
DiseaseHereditary non-polyposis colorectal cancer syndrome

SMARCA4 ATM

1.20e-0327562C1112155
DiseaseSezary Syndrome

SMARCA4 ARID1A

1.20e-0327562C0036920
Diseasecholesterol to total lipids in small LDL percentage

SMARCA4 APOB

1.20e-0327562EFO_0022241
Diseasecholesterol to total lipids in medium LDL percentage

SMARCA4 APOB

1.20e-0327562EFO_0022238
Diseaseprostate carcinoma in situ (is_marker_for)

ATM LEF1

1.30e-0328562DOID:8634 (is_marker_for)
Diseaseantihyperlipidemic drug use measurement

SMARCA4 APOB ARID1A

1.38e-03115563EFO_0803367
DiseaseHereditary Nonpolyposis Colorectal Cancer

SMARCA4 ATM

1.39e-0329562C1333990
Diseasevery low density lipoprotein cholesterol measurement

NCOR2 SMARCA4 APOB ARID1A

1.51e-03260564EFO_0008317
Diseasecardiovascular disease

NPR3 PKHD1 SMARCA4 NAV1 APOB

1.74e-03457565EFO_0000319
Diseasecoronary artery disease

ENAM WBP2 NPR3 PKHD1 SMARCA4 APOB PLCB2 RAPGEF2

1.78e-031194568EFO_0001645
Diseaseceliac disease

NAV1 FASLG RGS1

1.79e-03126563EFO_0001060

Protein segments in the cluster

PeptideGeneStartEntry
RMYLKHGSPVKMMES

DENND10P1

111

Q6NSW5
RRMDQMMPGKTKADA

ARID5A

186

Q03989
TFPKMMGKASANEML

CDY1

431

Q9Y6F8
ITFPKMMGKASANEM

CDY2A

431

Q9Y6F7
KRYMAPEMLDDTMNV

ACVR1C

366

Q8NER5
YPVKRTTKMAGMMIA

CHRM2

131

P08172
GNTMYPGMKARMEKE

ACTR5

496

Q9H9F9
YSMLFSPTEKGESMM

DISP1

451

Q96F81
MMLAIKEAASDMSPY

AP3B2

146

Q13367
RVAPAYAKMGEMMLA

NPR3

176

P17342
MDAMASPGKDNYRMK

KPNA5

1

O15131
SMVKSIKMNDVYGPM

DENND4A

1766

Q7Z401
AFMTMAAEIKKRMGP

RAB1B

161

Q9H0U4
LRTVDGSPMMKAAMY

PALM

156

O75781
DKMQKRRPKTFGMDM

RGS1

36

Q08116
KTNMEEMTEMQGGKY

ECT2

286

Q9H8V3
KPLNAFMLYMKEMRA

LEF1

301

Q9UJU2
NTSDMMGRMSYEPNK

ARID1A

1216

O14497
SRFPEDMMMLKKSAF

HDC

616

P19113
PDARGDKMSQDSMMK

DAB2

61

P98082
MGETMPSITKDMDLY

ALDH6A1

156

Q02252
NMNGLMADPMKVYKD

NCOR2

411

Q9Y618
MADPMKVYKDRQVMN

NCOR2

416

Q9Y618
TMGYMMAKKHLEINP

HSP90AB1

616

P08238
METMASPGKDNYRMK

KPNA6

1

O60684
MVPSYMAMTTAAKRK

KIF18A

816

Q8NI77
KDLGNLMRTMGYMPT

CABP5

51

Q9NP86
EKPKDMGFTRLMQAM

MICU1

446

Q9BPX6
GNRPMEMMDREKAYI

PDE2A

841

O00408
KMMSFDTRAPMAAQG

GNA13

121

Q14344
YNSNMSPEEKMMKRF

NOP14

91

P78316
RSFMMEVKDPNMKGA

RBBP6

196

Q7Z6E9
MKMEKGEMYGNSPRF

ETAA1

716

Q9NY74
EMEKEETMSMYNPRK

PPP1R3A

816

Q16821
NGMMKRDGMKIPTYK

ATM

2501

Q13315
LKLSNDMMGSYAEMK

APOB

1736

P04114
PDDEMMKRNMAYYKS

CRTAP

176

O75718
FPEFLGMMARKMKDT

CALML3

66

P27482
RMPGFSSKSEEMMRY

ENAM

46

Q9NRM1
RMYLKHGSPVKMMES

DENND10

111

Q8TCE6
PGQMEMLKLTMNKRY

NXF2

211

Q9GZY0
KSGYMSDSDLMGKTM

NAV1

386

Q8NEY1
KMSIEYKYEMMPNRT

NKRF

361

O15226
DDPRYNQMKGMGMRS

SMARCA4

86

P51532
YSMSEKMLGSRDMGA

PKHD1

2171

P08F94
MSALRGMKLMYKGED

AKAP17A

231

Q02040
YQMAKSNSGFMAMVK

APOL5

246

Q9BWW9
VSPTMDKEYMKGVMR

RAPGEF2

201

Q9Y4G8
MSYMRGKMQNSDCPK

RNASE13

56

Q5GAN3
YKESTYAKGKNMAMM

UBTFL6

306

P0CB48
KGTRMDSSNYMPQMF

PLCB2

606

Q00722
KPLNAFMLYMKEMRA

TCF7

271

P36402
SKYPQDLVMMEGKMM

FASLG

216

P48023
YMSMQKPMTKTSVKA

WASHC4

461

Q2M389
NMKSPMVRKYAFHMI

TRAPPC8

551

Q9Y2L5
ISMMAESYNQPKAMK

SCN11A

1381

Q9UI33
RYMQKMGMTEDDKRN

VAV2

186

P52735
PMLKESFEGMKMRST

TMEM87A

486

Q8NBN3
QMKMYRGFTKMPHVQ

TIMP3

66

P35625
SKGKDAMQSFMMPFY

WBP2

61

Q969T9