Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionGABA-gated chloride ion channel activity

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

9.06e-1018535GO:0022851
GeneOntologyMolecularFunctionGABA-A receptor activity

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

1.23e-0919535GO:0004890
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

GABRR1 GABRR2 SLC12A2 UCP2 BEST3 GABRR3 GABRA4 GABRA5

1.32e-09125538GO:0015108
GeneOntologyMolecularFunctionGABA receptor activity

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

2.76e-0922535GO:0016917
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

GABRR1 GABRR2 BEST3 GABRR3 GABRA4 GABRA5

3.79e-0950536GO:0099095
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

GABRR1 GABRR2 SLC12A2 UCP2 BEST3 GABRR3 GABRA4 GABRA5

5.90e-09151538GO:0008509
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

GABRR1 GABRR2 SLC12A2 UCP2 BEST3 GABRR3 GABRA4 GABRA5

1.57e-08171538GO:0015103
GeneOntologyMolecularFunctionchloride channel activity

GABRR1 GABRR2 BEST3 GABRR3 GABRA4 GABRA5

1.04e-0786536GO:0005254
GeneOntologyMolecularFunctionmonoatomic anion channel activity

GABRR1 GABRR2 BEST3 GABRR3 GABRA4 GABRA5

3.07e-07103536GO:0005253
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

7.95e-0765535GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

7.95e-0765535GO:0022824
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

1.86e-0677535GO:0005230
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

6.75e-06100535GO:0030594
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GABRR1 GABRR2 BEST3 GABRR3 GABRA4 GABRA5

1.19e-05193536GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

GABRR1 GABRR2 BEST3 GABRR3 GABRA4 GABRA5

1.33e-05197536GO:0022834
GeneOntologyMolecularFunctiontransporter activity

GABRR1 GABRR2 SLC12A2 UCP2 LRP2 BEST3 LRP6 SLC47A1 SLC35E2B MFSD10 GABRR3 GABRA4 GABRA5

2.36e-0512895313GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

GABRR1 GABRR2 SLC12A2 UCP2 BEST3 LRP6 SLC47A1 SLC35E2B MFSD10 GABRR3 GABRA4 GABRA5

4.78e-0511805312GO:0022857
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

GABRR1 GABRR2 SLC12A2 UCP2 BEST3 SLC47A1 GABRR3 GABRA4 GABRA5

1.55e-04758539GO:0015318
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

GABRR1 GABRR2 SLC12A2 UCP2 BEST3 SLC47A1 GABRR3 GABRA4 GABRA5

2.17e-04793539GO:0015075
GeneOntologyMolecularFunctiongated channel activity

GABRR1 GABRR2 BEST3 GABRR3 GABRA4 GABRA5

2.48e-04334536GO:0022836
GeneOntologyMolecularFunctionbenzodiazepine receptor activity

GABRA4 GABRA5

3.74e-0411532GO:0008503
GeneOntologyMolecularFunctionchannel activity

GABRR1 GABRR2 SLC12A2 BEST3 GABRR3 GABRA4 GABRA5

4.51e-04525537GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GABRR1 GABRR2 SLC12A2 BEST3 GABRR3 GABRA4 GABRA5

4.56e-04526537GO:0022803
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GABRR2 GABRA4 GABRA5

4.67e-0457533GO:1904315
GeneOntologyMolecularFunctioninsulin-like growth factor I binding

INSR LRP2

5.29e-0413532GO:0031994
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GABRR2 GABRA4 GABRA5

5.43e-0460533GO:0099529
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP2 LRP6

8.10e-0416532GO:0005041
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GABRR2 GABRA4 GABRA5

1.04e-0375533GO:0098960
GeneOntologyMolecularFunctioninsulin-like growth factor binding

INSR LRP2

1.15e-0319532GO:0005520
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GABRR1 GABRR2 BEST3 GABRR3 GABRA4 GABRA5

1.31e-03459536GO:0005216
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP2 LRP6

1.41e-0321532GO:0030228
GeneOntologyMolecularFunctioncargo receptor activity

INSR LRP2 LRP6

1.50e-0385533GO:0038024
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GABRR1 GABRA5

1.84e-0324532GO:0099507
GeneOntologyMolecularFunctionhormone binding

CRYM INSR LRP2

2.59e-03103533GO:0042562
GeneOntologyMolecularFunctionmonocarboxylic acid binding

ACACB INSR CYP4F11

2.88e-03107533GO:0033293
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

GAS2L1 KDM5B CRYM TCERG1 RAPGEF4 AKIRIN2 DDX20 ACTL6A ACTN1

3.20e-031160539GO:0030674
GeneOntologyMolecularFunctiontranscription coregulator activity

KDM5B CRYM TCERG1 AKIRIN2 ACTL6A ACTN1

3.62e-03562536GO:0003712
GeneOntologyMolecularFunctionantiporter activity

UCP2 SLC47A1 SLC35E2B

5.88e-03138533GO:0015297
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC12A2 UCP2 SLC47A1 SLC35E2B

7.84e-03296534GO:0015291
GeneOntologyMolecularFunctionprotein domain specific binding

GABRR1 GABRR2 INSR LRP2 DDX20 ACTN1 GABRR3

8.06e-03875537GO:0019904
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

GABRR1 GABRR2 PLXNC1 INSR LRP6 OR7G2 GABRR3 GABRA4 GABRA5

8.68e-031353539GO:0004888
GeneOntologyMolecularFunctionmolecular adaptor activity

GAS2L1 KDM5B CRYM TCERG1 RAPGEF4 AKIRIN2 DDX20 ACTL6A ACTN1

8.80e-031356539GO:0060090
GeneOntologyBiologicalProcessgamma-aminobutyric acid signaling pathway

GABRR1 GABRR2 SLC12A2 GABRR3 GABRA4 GABRA5

3.70e-1035546GO:0007214
GeneOntologyBiologicalProcesschloride transmembrane transport

GABRR1 GABRR2 SLC12A2 UCP2 BEST3 GABRR3 GABRA4 GABRA5

4.96e-10112548GO:1902476
GeneOntologyBiologicalProcesschloride transport

GABRR1 GABRR2 SLC12A2 UCP2 BEST3 GABRR3 GABRA4 GABRA5

1.44e-09128548GO:0006821
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

GABRR1 GABRR2 SLC12A2 UCP2 BEST3 GABRR3 GABRA4 GABRA5

2.08e-09134548GO:0098661
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

GABRR1 GABRR2 SLC12A2 UCP2 BEST3 GABRR3 GABRA4 GABRA5

5.94e-09153548GO:0098656
GeneOntologyBiologicalProcessinorganic anion transport

GABRR1 GABRR2 SLC12A2 UCP2 BEST3 GABRR3 GABRA4 GABRA5

2.13e-08180548GO:0015698
GeneOntologyBiologicalProcessmonoatomic anion transport

GABRR1 GABRR2 SLC12A2 UCP2 BEST3 GABRR3 GABRA4 GABRA5

2.42e-08183548GO:0006820
GeneOntologyBiologicalProcessbranching involved in mammary gland duct morphogenesis

KDM5B SLC12A2 LRP6

6.55e-0530543GO:0060444
GeneOntologyBiologicalProcessmammary gland duct morphogenesis

KDM5B SLC12A2 LRP6

2.23e-0445543GO:0060603
GeneOntologyBiologicalProcessmammary duct terminal end bud growth

KDM5B SLC12A2

2.39e-049542GO:0060763
GeneOntologyCellularComponentGABA-A receptor complex

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

1.08e-0919545GO:1902711
GeneOntologyCellularComponentGABA receptor complex

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

1.88e-0921545GO:1902710
GeneOntologyCellularComponentchloride channel complex

GABRR1 GABRR2 BEST3 GABRR3 GABRA4 GABRA5

7.32e-0957546GO:0034707
GeneOntologyCellularComponentGABA-ergic synapse

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

6.48e-05164545GO:0098982
GeneOntologyCellularComponentreceptor complex

GABRR1 GABRR2 PLXNC1 INSR LRP2 GABRR3 GABRA4 GABRA5

1.14e-04581548GO:0043235
GeneOntologyCellularComponentcell body membrane

SLC12A2 INSR GABRA5

2.44e-0447543GO:0044298
GeneOntologyCellularComponentdendrite membrane

INSR GABRA4 GABRA5

4.10e-0456543GO:0032590
GeneOntologyCellularComponentmonoatomic ion channel complex

GABRR1 GABRR2 BEST3 GABRR3 GABRA4 GABRA5

4.17e-04378546GO:0034702
GeneOntologyCellularComponentbrush border

RAPGEF4 LRP2 ACTN1 MFSD10

6.41e-04152544GO:0005903
GeneOntologyCellularComponentcell projection membrane

SLC12A2 INSR LRP2 MFSD10 GABRA4 GABRA5

8.30e-04431546GO:0031253
GeneOntologyCellularComponentneuron projection membrane

INSR GABRA4 GABRA5

1.25e-0382543GO:0032589
GeneOntologyCellularComponenttranscription repressor complex

AKIRIN2 DDX20 PASD1

1.48e-0387543GO:0017053
GeneOntologyCellularComponenttransmembrane transporter complex

GABRR1 GABRR2 BEST3 GABRR3 GABRA4 GABRA5

2.23e-03523546GO:1902495
GeneOntologyCellularComponentcluster of actin-based cell projections

RAPGEF4 LRP2 ACTN1 MFSD10

2.63e-03223544GO:0098862
GeneOntologyCellularComponentcontractile actin filament bundle

GAS2L1 MYH7 ACTN1

2.68e-03107543GO:0097517
GeneOntologyCellularComponentstress fiber

GAS2L1 MYH7 ACTN1

2.68e-03107543GO:0001725
GeneOntologyCellularComponenttransporter complex

GABRR1 GABRR2 BEST3 GABRR3 GABRA4 GABRA5

2.86e-03550546GO:1990351
GeneOntologyCellularComponentactomyosin

GAS2L1 MYH7 ACTN1

3.44e-03117543GO:0042641
GeneOntologyCellularComponentactin filament bundle

GAS2L1 MYH7 ACTN1

3.53e-03118543GO:0032432
GeneOntologyCellularComponentpostsynaptic membrane

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

3.87e-03405545GO:0045211
DomainGABAA/Glycine_rcpt

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

5.40e-0923545IPR006028
DomainNeurotransmitter_ion_chnl_CS

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

1.87e-0745545IPR018000
DomainNeur_chan_memb

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

2.09e-0746545PF02932
DomainNeur_chan_LBD

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

2.34e-0747545PF02931
DomainNEUROTR_ION_CHANNEL

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

2.34e-0747545PS00236
DomainNeurotrans-gated_channel_TM

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

2.34e-0747545IPR006029
Domain-

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

2.34e-07475452.70.170.10
DomainNeur_channel

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

2.34e-0747545IPR006201
DomainNeur_chan_lig-bd

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

2.34e-0747545IPR006202
DomainGABAAa_rho_rcpt

GABRR1 GABRR2

8.21e-062542IPR008057
DomainGABAAa_rcpt

GABRA4 GABRA5

1.22e-046542IPR001390
DomainLdl_recept_b

LRP2 LRP6

7.30e-0414542PF00058
DomainLDLRB

LRP2 LRP6

7.30e-0414542PS51120
DomainLY

LRP2 LRP6

8.41e-0415542SM00135
DomainLDLR_classB_rpt

LRP2 LRP6

8.41e-0415542IPR000033
Domain-

LRP2 LRP6

5.68e-03395422.120.10.30
DomainLDLR_class-A_CS

LRP2 LRP6

5.97e-0340542IPR023415
DomainLdl_recept_a

LRP2 LRP6

7.50e-0345542PF00057
Domain-

LRP2 LRP6

7.83e-03465424.10.400.10
Domain6-blade_b-propeller_TolB-like

LRP2 LRP6

7.83e-0346542IPR011042
DomainLDLRA_1

LRP2 LRP6

8.50e-0348542PS01209
DomainLDLRA_2

LRP2 LRP6

8.85e-0349542PS50068
DomainLDrepeatLR_classA_rpt

LRP2 LRP6

8.85e-0349542IPR002172
DomainLDLa

LRP2 LRP6

8.85e-0349542SM00192
PathwayREACTOME_GABA_RECEPTOR_ACTIVATION

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

1.75e-0660485M976
PathwayREACTOME_GABA_RECEPTOR_ACTIVATION

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

1.75e-0660485MM15708
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

1.25e-04144485MM14501
PathwayBIOCARTA_FLUMAZENIL_PATHWAY

GABRA4 GABRA5

4.03e-049482M22034
PathwayBIOCARTA_GABA_PATHWAY

GABRA4 GABRA5

5.02e-0410482MM1401
PathwayBIOCARTA_GABA_PATHWAY

GABRA4 GABRA5

5.02e-0410482M477
PathwayWP_PRADERWILLI_AND_ANGELMAN_SYNDROME

GABRR1 GABRR2 GABRR3 GABRA5

5.06e-04109484M39542
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

6.38e-04205485M752
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

7.27e-04211485MM14502
PathwayREACTOME_LYSINE_CATABOLISM

PHYKPL CRYM

7.33e-0412482M27680
PathwayREACTOME_LYSINE_CATABOLISM

PHYKPL CRYM

7.33e-0412482MM15400
Pubmed

Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

6.30e-111854519078961
Pubmed

Genetic linkage and radiation hybrid mapping of the three human GABA(C) receptor rho subunit genes: GABRR1, GABRR2 and GABRR3.

GABRR1 GABRR2 GABRR3

3.54e-09354310542332
Pubmed

GABAC receptors are functionally expressed in the intermediate zone and regulate radial migration in the embryonic mouse neocortex.

GABRR1 GABRR2 GABRR3

3.54e-09354320123002
Pubmed

Association study of 182 candidate genes in anorexia nervosa.

GABRR1 GABRR2 ACACB UCP2 INSR GABRA4 GABRA5

1.38e-0818254720468064
Pubmed

Gamma-aminobutyric acid (GABA) receptor rho (GABRR) polymorphisms and risk for essential tremor.

GABRR1 GABRR2 GABRR3

1.41e-08454320820800
Pubmed

ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2.

GABRR1 GABRR2 GABRR3

3.53e-08554312431995
Pubmed

PNUTS forms a trimeric protein complex with GABA(C) receptors and protein phosphatase 1.

GABRR1 GABRR2 GABRR3

3.53e-08554318325784
Pubmed

Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism.

GABRR2 GABRA4 GABRA5

1.23e-07754316080114
Pubmed

Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

1.75e-078154522723691
Pubmed

The N-terminal domain of human GABA receptor rho1 subunits contains signals for homooligomeric and heterooligomeric interaction.

GABRR1 GABRR2

2.37e-0625429153229
Pubmed

Elimination of the rho1 subunit abolishes GABA(C) receptor expression and alters visual processing in the mouse retina.

GABRR1 GABRR2

2.37e-06254212019334
Pubmed

Gene-based interaction analysis shows GABAergic genes interacting with parenting in adolescent depressive symptoms.

GABRR1 GABRR2

2.37e-06254228660714
Pubmed

GABRR1 and GABRR2, encoding the GABA-A receptor subunits rho1 and rho2, are associated with alcohol dependence.

GABRR1 GABRR2

2.37e-06254219536785
Pubmed

Gamma-aminobutyric acid (GABA) receptors genes polymorphisms and risk for restless legs syndrome.

GABRR3 GABRA4

2.37e-06254229720720
Pubmed

MAP3K4 promotes fetal and placental growth by controlling the receptor tyrosine kinases IGF1R/IR and Akt signaling pathway.

INSR MAP3K4

7.09e-06354235921893
Pubmed

Cloning and characterization of mouse GABA(C) receptor subunits.

GABRR1 GABRR2

7.09e-0635429507960
Pubmed

Consensus phosphorylation sites of human GABA(c)/GABArho receptors are not critical for inhibition by protein kinase C activation.

GABRR1 GABRR2

7.09e-0635429839716
Pubmed

GABAC receptor sensitivity is modulated by interaction with MAP1B.

GABRR1 GABRR2

7.09e-06354211102469
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

PCYT1A MYH7 TCERG1 TSR1 SMC1A SRP19 CCT2 DDX20 ACTL6A ACTN1

9.50e-061149541035446349
Pubmed

Functional interaction of BRCA1/ATM-associated BAAT1 with the DNA-PK catalytic subunit.

SMC1A BRAT1

1.42e-05454222977523
Pubmed

LRP6 enhances glucose metabolism by promoting TCF7L2-dependent insulin receptor expression and IGF receptor stabilization in humans.

INSR LRP6

1.42e-05454223395167
Pubmed

Developmentally regulated expression of GABA receptor rho1 and rho2 subunits, L7 and cone-rod homeobox (CRX) genes in mouse retina.

GABRR1 GABRR2

1.42e-05454211520487
Pubmed

Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisition.

AKAP4 LRP6

1.42e-05454223675479
Pubmed

Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability.

UCP2 INSR

1.42e-05454227518562
Pubmed

Composition of the GABA(A) receptors of retinal dopaminergic neurons.

GABRA4 GABRA5

1.42e-05454210479684
Pubmed

GABAA receptor signaling in caudal periaqueductal gray regulates maternal aggression and maternal care in mice.

GABRA4 GABRA5

3.54e-05654220457185
Pubmed

Developmental changes in the expression of gamma-aminobutyric acidA/benzodiazepine receptor subunit mRNAs in the murine inferior olivary complex.

GABRA4 GABRA5

4.94e-0575427560270
Pubmed

Identification of a putative gamma-aminobutyric acid (GABA) receptor subunit rho2 cDNA and colocalization of the genes encoding rho2 (GABRR2) and rho1 (GABRR1) to human chromosome 6q14-q21 and mouse chromosome 4.

GABRR1 GABRR2

4.94e-0575421315307
Pubmed

A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells.

GABRR1 GABRR2

4.94e-0575428940147
Pubmed

Mouse thioredoxin gene maps on chromosome 4, whereas its pseudogene maps on chromosome 1.

GABRR1 GABRR2

6.59e-0585428088797
Pubmed

Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation.

GABRA4 GABRA5

6.59e-05854218185516
Pubmed

The Effect of the NFκB-USP9X-Cx43 Axis on the Dynamic Balance of Bone Formation/Degradation during Ossification of the Posterior Longitudinal Ligament of the Cervical Spine.

MYH7 CCT2 ACTN1

8.30e-055454335391932
Pubmed

Identification of novel genetic loci for bone size and mechanosensitivity in an ENU mutant exhibiting decreased bone size.

GABRR1 GABRR2

8.46e-05954215883645
Pubmed

Phosphorylation of the recombinant rho1 GABA receptor.

GABRR1 GABRR2

8.46e-05954212175859
Pubmed

The functional interactome landscape of the human histone deacetylase family.

SMC1A CCT2 DDX20 ACTL6A EMSY

8.67e-0528954523752268
Pubmed

A generic approach for the purification of signaling complexes that specifically interact with the carboxyl-terminal domain of G protein-coupled receptors.

MYH7 CRYM CCT2

8.77e-055554318448421
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

GABRR1 GABRR2 RAPGEF4 GABRR3 GABRA5

1.03e-0430054519086053
Pubmed

Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing.

GABRR1 GABRR2

1.06e-041054230902970
Pubmed

Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder.

GABRR1 GABRR2

1.06e-041054220583128
Pubmed

Aerobic glycolysis tunes YAP/TAZ transcriptional activity.

TSR1 CCT2 ACTL6A ACTN1

1.20e-0416254425796446
Pubmed

A forward genetic screen in mice identifies mutants with abnormal cortical patterning.

LRP2 LRP6

1.29e-041154223968836
Pubmed

Review: Central non-glucocorticoid inhibitors of the hypothalamo-pituitary-adrenal axis.

GABRA4 GABRA5

1.29e-04115429924185
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP2 LRP6

1.29e-041154224639464
Pubmed

Region and layer-specific expression of GABAA receptor isoforms and KCC2 in developing cortex.

GABRA4 GABRA5

1.29e-041154238894703
Pubmed

Nonsyndromic Genetic Hyperinsulinism Overview

UCP2 INSR

1.55e-041254220301549
Pubmed

Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice.

GABRA4 GABRA5

1.83e-041354222569571
Pubmed

IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development.

MYH7 INSR

1.83e-041354221429986
Pubmed

Involvement of neurotransmitters in the action of growth hormone-releasing hormone antagonist on passive avoidance learning.

GABRA4 GABRA5

1.83e-041354222640814
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

SETX SLC12A2 ACACB INSR BSDC1 CCT2 PEAK1

1.92e-0477754735844135
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

TCERG1 CCT2 ACTL6A ACTN1 PEAK1 EMSY

2.05e-0454954638280479
Pubmed

Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathy.

MYH7 ACTN1

2.13e-041454224938781
Pubmed

The biochemical anatomy of cortical inhibitory synapses.

GABRA4 GABRA5

2.13e-041454222768092
Pubmed

Functional domains of the FgfrL1 receptor.

MYH7 LRP2

2.13e-041454231923383
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

LRP2 LRP6

2.13e-041454217389516
Pubmed

Induction of expression of growth-related genes by FGF-4 in mouse fibroblasts.

GABRR1 GABRR2

2.13e-04145428649829
Pubmed

Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?

ACACB UCP2 INSR GABRA4

2.29e-0419254420602615
Pubmed

Essential role of MESP1-RING1A complex in cardiac differentiation.

MYH7 SMC1A

2.45e-041554236413948
Pubmed

DelK32-lamin A/C has abnormal location and induces incomplete tissue maturation and severe metabolic defects leading to premature death.

MYH7 ACACB

2.80e-041654222090424
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

TCERG1 TSR1 SMC1A CCT2 ACTL6A ACTN1

2.82e-0458354629844126
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

SETX TCERG1 SMC1A SRP19 CCT2 ACTL6A ACTN1 EMSY

2.84e-04110354834189442
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

MYH7 SETX TCERG1 PLEKHG4 SMC1A ACTL6A EMSY

3.48e-0485754725609649
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

PCYT1A SETX TSR1 SMC1A ACTL6A EMSY

3.53e-0460854636089195
Pubmed

A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice.

MYH7 ACTN1

3.56e-041854224840128
Pubmed

Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle.

SRP19 DDX20

3.56e-041854223221635
Pubmed

Proteomics analysis of the estrogen receptor alpha receptosome.

TCERG1 SMC1A CCT2

4.16e-049354320348541
Pubmed

Early growth response 1 (Egr-1) directly regulates GABAA receptor α2, α4, and θ subunits in the hippocampus.

GABRA4 GABRA5

4.88e-042154225708312
Pubmed

Temporal and spatial transcriptional programs in murine kidney development.

CRYM DDX20

4.88e-042154215998744
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

LRP2 LRP6

4.88e-042154221337463
Pubmed

Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney.

CRYM SLC12A2

5.36e-042254229449449
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

SLC12A2 INSR LRP2

5.93e-0410554330280653
Pubmed

Capillary endothelial fatty acid binding proteins 4 and 5 play a critical role in fatty acid uptake in heart and skeletal muscle.

MYH7 UCP2

6.94e-042554223968980
Pubmed

Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation.

SMC1A LRP2

7.51e-042654228087629
Pubmed

LARP7 Protects Against Heart Failure by Enhancing Mitochondrial Biogenesis.

MYH7 UCP2

7.51e-042654233663221
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PCYT1A KDM5B TCERG1 SMC1A RAPGEF4 LRP2 CCT2 ACTN1

7.80e-04128554835914814
Pubmed

Charting the molecular network of the drug target Bcr-Abl.

CCT2 ACTL6A ACTN1 PEAK1

7.83e-0426654419380743
Pubmed

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

SLC12A2 INSR BSDC1 LRP6 PEAK1

7.86e-0446754530194290
Pubmed

Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2.

MYH7 ACTN1

8.10e-042754236899856
Pubmed

Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.

ACACB UCP2 INSR

8.12e-0411754318996102
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

SETX RAPGEF4 CCT2 PASD1

9.11e-0427754430745168
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

ACACB TCERG1 TSR1 SMC1A CCT2 DDX20 ACTL6A EMSY

9.20e-04131854830463901
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

SMC1A CCT2 EMSY

9.39e-0412354326912792
Pubmed

DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal.

GABRR1 GABRA4

1.00e-033054236460641
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

ACACB TOPAZ1 RAPGEF4 ACTL6A MAP3K4

1.04e-0349754536774506
Pubmed

Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis.

CDC34 ZRANB1

1.07e-033154225527291
Pubmed

TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin.

SMC1A ACTL6A

1.07e-033154226095369
Pubmed

Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation.

GABRA4 GABRA5

1.07e-033154219736351
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SETX TCERG1 PLEKHG4 SMC1A CCT2 DDX20 ACTL6A ACTN1

1.09e-03135354829467282
Pubmed

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.

TSR1 CCT2 DDX20 ACTL6A

1.22e-0330054428561026
Pubmed

PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria.

MYDGF CCT2 ACTN1

1.25e-0313654322304920
Pubmed

Inceptor counteracts insulin signalling in β-cells to control glycaemia.

ACACB INSR

1.29e-033454233505018
Pubmed

The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation.

LRP2 ACTL6A

1.36e-033554232504627
Pubmed

Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens.

AP3B2 INSR

1.44e-03365429344654
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

PCYT1A TCERG1 TSR1 SMC1A SRP19 CCT2 DDX20 ACTN1

1.45e-03141554828515276
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

MYH7 TSR1 SMC1A CCT2 ACTN1

1.47e-0353854528524877
Pubmed

Nuclear Functions of Nucleolin through Global Proteomics and Interactomic Approaches.

TSR1 SMC1A ACTL6A

1.51e-0314554327049334
Pubmed

A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.

SMC1A UGGT2 CCT2

1.51e-0314554323349634
Pubmed

Autophagy in Myf5+ progenitors regulates energy and glucose homeostasis through control of brown fat and skeletal muscle development.

UCP2 INSR

1.52e-033754223907538
Pubmed

Human transcription factor protein interaction networks.

ACACB TCERG1 SMC1A LRP2 LRP6 CCT2 ACTL6A EMSY

1.54e-03142954835140242
Cytoband6q15

GABRR1 GABRR2 AKIRIN2

6.75e-06315436q15
CytobandEnsembl 112 genes in cytogenetic band chr6q15

GABRR1 GABRR2 AKIRIN2

3.08e-0551543chr6q15
CytobandEnsembl 112 genes in cytogenetic band chr19p13

MICOS13 INSR MYDGF CDC34 OR7G2 CYP4F11

3.42e-04797546chr19p13
CytobandEnsembl 112 genes in cytogenetic band chr12q15

BEST3 CCT2

2.01e-0356542chr12q15
Cytoband19p13.3

MICOS13 MYDGF CDC34

2.77e-0323754319p13.3
GeneFamilyGamma-aminobutyric acid type A receptor subunits

GABRR1 GABRR2 GABRR3 GABRA4 GABRA5

2.30e-1019355563
GeneFamilyLow density lipoprotein receptors

LRP2 LRP6

2.80e-0413352634
GeneFamilySolute carriers

SLC12A2 UCP2 SLC47A1 SLC35E2B

6.88e-03395354752
CoexpressionGSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP

KDM5B INSR RAPGEF4 LRP6 ACTN1

2.10e-05162545M7005
CoexpressionDESCARTES_FETAL_EYE_BIPOLAR_CELLS

GABRR1 GABRR3 GABRA5

2.33e-0527543M40181
CoexpressionNAKAYA_MONOCYTE_FLUMIST_AGE_18_50YO_7DY_UP

GAS2L1 SETX ACACB PLXNC1 LAIR1 UGGT2 CCT2

5.35e-05477547M40930
CoexpressionGSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_6H_UP

KDM5B SETX INSR RAPGEF4 ACTN1

5.74e-05200545M6415
CoexpressionSWEET_LUNG_CANCER_KRAS_UP

PCYT1A MYH7 SLC12A2 TSR1 LRP2 MYDGF ACTN1

5.86e-05484547M19097
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-MEP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CRYM PLXNC1 LRP2 CCT2 CYP4F11 GABRA5

8.58e-08181546ee207ea171e2ffc22a7f850be57bb118a87e0f81
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GABRR1 AKAP4 AP3B2 BEST3 ZKSCAN2

1.98e-06170545941d637cf76918ee4b0a1833abd1a42593cb8b1a
DrugCGS 8216

GABRR1 GABRR2 GABRA4 GABRA5

1.10e-0633544CID000104916
DrugAC1L2FYN

GABRR1 GABRR2 GABRA4 GABRA5

1.10e-0633544CID000071333
Drugflurazepam

GABRR1 GABRR2 GABRA4 GABRA5

1.40e-0635544CID000003393
DrugChlordiazepoxide

GABRR1 GABRA4 GABRA5

1.50e-0610543DB00475
DrugClobazam

GABRR1 GABRA4 GABRA5

1.50e-0610543DB00349
DrugBromazepam

GABRR1 GABRA4 GABRA5

1.50e-0610543DB01558
DrugClonazepam

GABRR1 GABRA4 GABRA5

1.50e-0610543DB01068
DrugOxazepam

GABRR1 GABRA4 GABRA5

1.50e-0610543DB00842
DrugMidazolam

GABRR1 GABRA4 GABRA5

1.50e-0610543DB00683
DrugFlurazepam

GABRR1 GABRA4 GABRA5

1.50e-0610543DB00690
DrugAC1L1B1W

GABRR1 GABRR2 SLC12A2 GABRA4 GABRA5

1.66e-0684545CID000001248
Drugsecobarbital

GABRR1 GABRR2 GABRA4 GABRA5

1.76e-0637544CID000005193
DrugDMCM

GABRR1 GABRR2 GABRA4 GABRA5

1.96e-0638544CID000104999
DrugAlprazolam

GABRR1 GABRA4 GABRA5

2.05e-0611543DB00404
DrugTemazepam

GABRR1 GABRA4 GABRA5

2.05e-0611543DB00231
DrugNitrazepam

GABRR1 GABRA4 GABRA5

2.05e-0611543DB01595
DrugLorazepam

GABRR1 GABRA4 GABRA5

2.05e-0611543DB00186
DrugTriazolam

GABRR1 GABRA4 GABRA5

2.05e-0611543DB00897
DrugClorazepate

GABRR1 GABRA4 GABRA5

2.05e-0611543DB00628
Drugzaleplon

GABRR1 GABRR2 GABRA4 GABRA5

2.19e-0639544CID000005719
DrugGabrene

GABRR1 GABRR2 GABRA4 GABRA5

2.42e-0640544CID005361323
Druggaboxadol

GABRR1 GABRR2 GABRA4 GABRA5

2.68e-0641544CID000003448
Drugzolpidem

GABRR1 GABRR2 GABRA4 GABRA5

3.26e-0643544CID000005732
Drugalpha IMGBL

GABRR2 GABRA4 GABRA5

3.55e-0613543CID000131516
Druglorazepam

GABRR1 GABRR2 GABRA4 GABRA5

3.57e-0644544CID000003958
Drugisoguvacine

GABRR2 SLC12A2 GABRA4 GABRA5

3.92e-0645544CID000003765
Drugheptachlor epoxide

GABRR1 GABRR2 GABRA4 GABRA5

4.28e-0646544CID000013930
Drugvigabatrin

GABRR1 GABRR2 GABRA4 GABRA5

5.53e-0649544CID000005665
DrugTBOB

PCYT1A GABRA4 GABRA5

5.62e-0615543CID000114986
Drugtriazolam

GABRR1 GABRR2 GABRA4 GABRA5

8.18e-0654544CID000005556
Drugdihydroxyaflavinine

GABRR1 GABRA4 GABRA5

8.38e-0617543CID000156857
Drugclorazepate

GABRR2 GABRA4 GABRA5

1.00e-0518543CID000002809
Drugflunitrazepam

GABRR1 GABRR2 GABRA4 GABRA5

1.17e-0559544CID000003380
DrugZK 93426

GABRR2 GABRA4 GABRA5

1.19e-0519543CID000115210
Drugmuscimol

GABRR1 GABRR2 SLC12A2 GABRA4 GABRA5

1.37e-05129545CID000004266
DrugEBOB

GABRR2 GABRA4 GABRA5

1.40e-0520543CID000115223
Druggamma-Aminobutyric Acid

GABRR1 GABRR3 GABRA4 GABRA5

1.42e-0562544ctd:D005680
Drugbeta-carboline

GABRR1 GABRR2 GABRA4 GABRA5

1.62e-0564544CID000064961
Drugnordiazepam

GABRR2 UCP2 GABRA4 GABRA5

1.62e-0564544CID000002997
Drugprazepam

GABRR2 GABRA4 GABRA5

1.63e-0521543CID000004890
Drugbicuculline methochloride

GABRR2 GABRA4 GABRA5

1.63e-0521543CID000123659
DrugR 5135

GABRR2 GABRA4 GABRA5

1.63e-0521543CID000119544
Drugpicrotoxinine

GABRR1 GABRR2 GABRA4 GABRA5

1.72e-0565544CID000004816
Drug6 mEq

SLC12A2 GABRA4 GABRA5

1.88e-0522543CID000126186
Drugimidazenil

GABRR2 GABRA4 GABRA5

1.88e-0522543CID000119194
Drugzolazepam

GABRR2 GABRA4 GABRA5

2.16e-0523543CID000035775
Drugfelbamate

GABRR1 GABRR2 GABRA4 GABRA5

2.31e-0570544CID000003331
Druggamma-acetylenic GABA

GABRR2 GABRA4 GABRA5

2.46e-0524543CID000003452
Drugmethohexital

GABRR1 GABRA4 GABRA5

2.46e-0524543CID000009034
Drugmedazepam

GABRR2 GABRA4 GABRA5

2.46e-0524543CID000004041
DrugSL 75102

GABRR2 GABRA4 GABRA5

2.46e-0524543CID005751746
DrugAntigens, Polyomavirus Transforming

KDM5B PHYKPL SETX TCERG1 SMC1A UCP2 CCT2 DDX20 ACTL6A

2.49e-05668549ctd:D000952
Drugisonipecotic acid

GABRR2 GABRA4 GABRA5

2.80e-0525543CID000003773
DrugP4-s

GABRR2 GABRA4 GABRA5

2.80e-0525543CID000004838
Drugbeta-CCE

GABRR2 GABRA4 GABRA5

2.80e-0525543CID000105078
Drugacamprosate

GABRR1 GABRR2 GABRA4 GABRA5

2.87e-0574544CID000071158
DrugSKF97541

GABRR2 GABRA4 GABRA5

3.15e-0526543CID000005230
DrugV-X-A

GABRR2 GABRA4 GABRA5

3.15e-0526543CID006369389
DrugAC1Q3ZOL

GABRR1 GABRR2 SLC12A2 ACTL6A GABRA4 GABRA5

3.27e-05258546CID000002376
Drugpitrazepin

GABRR2 GABRA4 GABRA5

3.54e-0527543CID000146222
Drugchlormethiazole

GABRR2 GABRA4 GABRA5

3.96e-0528543CID000010783
Drugmephobarbital

GABRR2 GABRA4 GABRA5

3.96e-0528543CID000008271
DrugMetformin

MYH7 SETX ACACB UCP2 INSR SLC47A1 ACTN1

4.26e-05400547ctd:D008687
Drugclonazepam

GABRR1 GABRR2 GABRA4 GABRA5

4.31e-0582544CID000002802
Drugetazolate

GABRR2 GABRA4 GABRA5

4.41e-0529543CID000003277
Drugguvacine

GABRR2 GABRA4 GABRA5

4.89e-0530543CID000003532
Drug3-isothujone

GABRR1 GABRA4 GABRA5

4.89e-0530543CID000011027
Drugallylglycine

GABRR2 GABRA4 GABRA5

4.89e-0530543CID000014044
DrugSKF89976A

GABRR2 GABRA4 GABRA5

5.41e-0531543CID000092409
Drugneostigmine

GABRR1 GABRR2 GABRA4 GABRA5

5.44e-0587544CID000004456
Drughomotaurine

GABRR2 GABRA4 GABRA5

5.96e-0532543CID000001646
Drug3-aminopropylphosphinic acid

GABRR2 GABRA4 GABRA5

5.96e-0532543CID006335948
Drugpregnanolone

GABRR1 GABRR2 GABRA4 GABRA5

6.21e-0590544CID000031402
DrugAOAA

GABRR1 GABRR2 GABRA4 GABRA5

6.48e-0591544CID000000285
Drugamobarbital

GABRR2 GABRA4 GABRA5

7.16e-0534543CID000002163
Drugtemazepam

GABRR2 GABRA4 GABRA5

7.16e-0534543CID000005391
DrugAspidium

KDM5B SLC12A2 SLC47A1 ACTL6A MFSD10

7.49e-05184545CID000000815
DrugFenbendazole [43210-67-9]; Up 200; 13.4uM; PC3; HT_HG-U133A

GABRR2 PCYT1A LRP6 ACTN1 CYP4F11

7.68e-051855454542_UP
Drugestazolam

GABRR2 GABRA4 GABRA5

7.82e-0535543CID000003261
DrugMeprobamate

GABRA4 GABRA5

8.23e-056542DB00371
DrugFlunitrazepam

GABRA4 GABRA5

8.23e-056542DB01544
DrugFG 7142

GABRR2 GABRA4 GABRA5

8.52e-0536543CID000004375
Drugalprazolam

GABRR1 GABRR2 CYP4F11 GABRA4 GABRA5

9.38e-05193545CID000002118
DrugThimerosal

GABRR1 GAS2L1 SETX DENND1B SLC12A2 ACACB PLEKHG4 PLXNC1 SMC1A UCP2 LRP6

9.76e-0511995411ctd:D013849
DrugOxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; HL60; HT_HG-U133A

GABRR2 PLXNC1 SMC1A LRP6 GABRA4

1.03e-041975453006_DN
Drugcyclothiazide

GABRR1 GABRR2 GABRA4 GABRA5

1.05e-04103544CID000002910
DrugGriseofulvin [126-07-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A

AKAP4 ACACB LAIR1 PEAK1 CYP4F11

1.06e-041985452293_UP
DrugOmeprazole [73590-58-6]; Down 200; 11.6uM; PC3; HT_HG-U133A

SETX ACACB UCP2 LRP6 EMSY

1.06e-041985456606_DN
DrugMorantel tartrate [26155-31-7]; Down 200; 10.8uM; PC3; HT_HG-U133A

SETX ACACB INSR LRP6 UGGT2

1.08e-041995457250_DN
DrugQuazepam

GABRR1 GABRA5

1.15e-047542DB01589
DrugInferno

PCYT1A INSR

1.15e-047542CID000006542
Drugendrine

GABRR1 GABRR2 GABRA4 GABRA5

1.17e-04106544CID000003048
Drugmidazolam

GABRR1 GABRR2 GABRA4 GABRA5

1.22e-04107544CID000004192
Druggamma-aminobutyric acid

GABRR1 GABRR2 PHYKPL SLC12A2 IL36B GABRA4 GABRA5

1.23e-04474547CID000000119
DrugCGP55845

GABRR2 GABRA4 GABRA5

1.26e-0441543CID000123885
Drugbarbital

GABRR2 GABRA4 GABRA5

1.36e-0442543CID000002294
Drug5 beta-alphaxalone

GABRR1 GABRA4 GABRA5

1.36e-0442543CID000068930
DrugAdinazolam

GABRR1 GABRA5

1.53e-048542DB00546
DrugFludiazepam

GABRR1 GABRA5

1.53e-048542DB01567
DrugClotiazepam

GABRR1 GABRA5

1.53e-048542DB01559
Diseasefatty liver disease (implicated_via_orthology)

ACACB INSR LRP6

2.24e-0531523DOID:9452 (implicated_via_orthology)
Diseaseautistic disorder (is_implicated_in)

GABRR2 RAPGEF4 GABRA4

5.65e-0542523DOID:12849 (is_implicated_in)
DiseaseN-acetylcarnosine measurement

GABRR1 GABRR2

8.47e-058522EFO_0022101
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GABRR1 GABRR2 GABRR3

8.98e-0549523DOID:0060037 (implicated_via_orthology)
Diseaseautistic disorder (is_marker_for)

GABRA4 GABRA5

1.99e-0412522DOID:12849 (is_marker_for)
Diseasenon-alcoholic fatty liver disease (biomarker_via_orthology)

ACACB UCP2 INSR

2.09e-0465523DOID:0080208 (biomarker_via_orthology)
DiseaseImpaired glucose tolerance

SLC12A2 INSR

8.90e-0425522C0271650
DiseaseHyperinsulinism

UCP2 INSR

1.12e-0328522C0020459
Diseasehypertension (implicated_via_orthology)

SLC12A2 UCP2 LRP2

1.51e-03128523DOID:10763 (implicated_via_orthology)
Diseasefatty liver disease (biomarker_via_orthology)

UCP2 INSR

1.55e-0333522DOID:9452 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
RSVSTAVYKRFPTMD

BEST3

141

Q8N1M1
DPESYVRASAVTAMG

BRAT1

556

Q6PJG6
ARPDEKAIMTYVSSF

ACTN1

231

P12814
ALYTKMVPAAVSHSE

BSDC1

171

Q9NW68
PASKIASEMAYEAVE

AKAP4

266

Q5JQC9
FSAAAASPQKYLRME

AKIRIN2

51

Q53H80
YMIASKEAVREGSPA

ACTL6A

221

O96019
ANALTKYMRDPTFVR

DDX20

251

Q9UHI6
AMAYANEVKRVVSSA

PHYKPL

186

Q8IUZ5
KEAASDMSPYVRKTA

AP3B2

151

Q13367
VMPAYSAAEDALTTK

CRYM

61

Q14894
MAVFGAAAPYLRKSE

MYH7

6

P12883
PVEKSVRRVMAQYAS

ACACB

1056

O00763
FATAIGMPVEKRYNS

MFSD10

71

Q14728
STKPMAESITYAAVA

LAIR1

271

Q6GTX8
SKPYVRVTMEEASRG

PCYT1A

56

P49585
PTRATYKDVSVVNVM

PLXNC1

561

O60486
LCKPYTVVDVSAAMA

PEAK1

471

Q9H792
VMSALSVAPSKAREY

MICOS13

91

Q5XKP0
YAPSRRMTSVATAKG

LRP6

1541

O75581
ARHSLPKVSYATAMD

GABRA4

306

P48169
SARNSLPKVAYATAM

GABRA5

306

P31644
VGLAPYSAVEKAMAR

KDM5B

946

Q9UGL1
FENPMYSARDSAVKV

LRP2

4521

P98164
VAAYVSARTMPEAKA

INSR

836

P06213
RGHTSMKAVYVEPAA

PASD1

216

Q8IV76
MKAVYVEPAAAAAAA

PASD1

221

Q8IV76
AVSASMPQVSYLKAV

GABRR3

316

A8MPY1
VNASMPRVSYIKAVD

GABRR1

331

P24046
EAAPKSYAIRDSRQM

IL36B

6

Q9NZH7
VRPFRSSEAYVEAMK

GAS2L1

16

Q99501
TSASAAVAPKDMIFY

CYP4F11

111

Q9HBI6
RMAATPGAATYVKTT

EMSY

521

Q7Z589
AMTKATPAVRTAYKF

DENND1B

436

Q6P3S1
VNASMPRVSYVKAVD

GABRR2

311

P28476
AAYMAPEVITRAKGE

MAP3K4

1506

Q9Y6R4
YVSVSDDARMIAALK

RAPGEF4

606

Q8WZA2
VQFPSRKSVMLYAAE

SRP19

96

P09132
VTLSPDYRTAMDKAD

PLEKHG4

411

Q58EX7
DSPRKTAVASVMYSV

OR7G2

266

Q8NG99
AIETAYAMVKHSPSV

SETX

1941

Q7Z333
NRTPGKEAVAMESYA

CCT2

426

P78371
YMVPAGFSVAASVRV

SLC47A1

306

Q96FL8
IASPVDVVKTRYMNS

UCP2

231

P55851
ADMALVATVYAPITF

TSR1

646

Q2NL82
TFSPANVDASVMYRK

CDC34

136

P49427
VESDPRYKAVDSSSM

TCERG1

821

O14776
PVARKGAVSSALYMA

SLC12A2

1171

P55011
GKPAANRAFVSMVYS

SMC1A

71

Q14683
YTSAAAVAMLVPARV

SLC35E2B

261

P0CK96
FEYVATMKLRNAVPA

TOPAZ1

1206

Q8N9V7
YKEMDALINSRASAP

ZKSCAN2

576

Q63HK3
AASQIMSAPVYDSIK

UGGT2

316

Q9NYU1
SARPRVKSSYSMENA

ZRANB1

71

Q9UGI0
MAYSKAAFERESDVP

MYDGF

121

Q969H8