Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transcription factor binding	BPTF ZBTB49 NCOA6 HNF1A CRTC3 KAT5 HDAC4 NFATC2 RB1 RUNX1 LMO4 EP300 ZFPM2	3.47e-07	753	61	13	GO:0008134
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	NFE2L3 PKNOX2 BPTF ZBTB49 HNF1A ZBTB38 HIVEP1 HDAC4 DACH2 NFATC2 TLX3 ZFHX3 RUNX1 KDM6A EP300	3.54e-06	1244	61	15	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	NFE2L3 PKNOX2 BPTF ZBTB49 HNF1A ZBTB38 HIVEP1 HDAC4 DACH2 NFATC2 TLX3 ZFHX3 RUNX1 KDM6A EP300	4.60e-06	1271	61	15	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	NFE2L3 PKNOX2 BPTF ZBTB49 HNF1A ZBTB38 HIVEP1 HDAC4 DACH2 NFATC2 RB1 TLX3 ZFHX3 RUNX1 KDM6A EP300	5.29e-06	1459	61	16	GO:0000977
GeneOntologyMolecularFunction	peptide 2-hydroxyisobutyryltransferase activity	KAT5 EP300	9.18e-06	2	61	2	GO:0106226
GeneOntologyMolecularFunction	peptide crotonyltransferase activity	KAT5 EP300	9.18e-06	2	61	2	GO:0140064
GeneOntologyMolecularFunction	peptide butyryltransferase activity	KAT5 EP300	9.18e-06	2	61	2	GO:0140065
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	ZBTB49 NCOA6 CRTC3 KAT5 HDAC4 RB1 RUNX1 LMO4 EP300 ZFPM2	9.69e-06	582	61	10	GO:0140297
GeneOntologyMolecularFunction	transcription coactivator binding	ZBTB49 HNF1A RUNX1 EP300	2.22e-05	54	61	4	GO:0001223
GeneOntologyMolecularFunction	transcription coregulator activity	NCOA6 ARID1B KAT5 HDAC4 RB1 GON4L LMO4 EP300 ZFPM2	4.89e-05	562	61	9	GO:0003712
GeneOntologyMolecularFunction	chromatin binding	NCOA6 HNF1A ARID1B KAT5 HDAC4 NFATC2 RUNX1 KDM6A EP300	3.84e-04	739	61	9	GO:0003682
GeneOntologyMolecularFunction	transcription corepressor activity	HDAC4 RB1 GON4L LMO4 ZFPM2	6.70e-04	229	61	5	GO:0003714
GeneOntologyMolecularFunction	transcription coregulator binding	ZBTB49 HNF1A RUNX1 EP300	8.86e-04	140	61	4	GO:0001221
GeneOntologyMolecularFunction	nuclear glucocorticoid receptor binding	NCOA6 EP300	1.68e-03	20	61	2	GO:0035259
GeneOntologyMolecularFunction	peroxisome proliferator activated receptor binding	NCOA6 EP300	1.86e-03	21	61	2	GO:0042975
GeneOntologyMolecularFunction	promoter-specific chromatin binding	HDAC4 RUNX1 EP300	2.09e-03	83	61	3	GO:1990841
GeneOntologyMolecularFunction	histone H4 acetyltransferase activity	KAT5 EP300	2.23e-03	23	61	2	GO:0010485
GeneOntologyMolecularFunction	transcription coactivator activity	NCOA6 ARID1B KAT5 EP300 ZFPM2	2.31e-03	303	61	5	GO:0003713
GeneOntologyMolecularFunction	molecular adaptor activity	NCOA6 ARID1B KAT5 HDAC4 NFATC2 RB1 SYN1 GON4L LMO4 EP300 ZFPM2	2.45e-03	1356	61	11	GO:0060090
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	NCOA6 ARID1B KAT5 HDAC4 RB1 SYN1 GON4L LMO4 EP300 ZFPM2	2.53e-03	1160	61	10	GO:0030674
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	NFE2L3 ZBTB49 HIVEP1 NFATC2 ZFHX3	2.93e-03	320	61	5	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	NFE2L3 ZBTB49 HIVEP1 NFATC2 ZFHX3	3.17e-03	326	61	5	GO:0001217
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	NFE2L3 PKNOX2 ZBTB49 HNF1A ZBTB38 HIVEP1 DACH2 NFATC2 TLX3 ZFHX3 RUNX1	3.35e-03	1412	61	11	GO:0000981
GeneOntologyMolecularFunction	acetyltransferase activity	FASN KAT5 EP300	3.97e-03	104	61	3	GO:0016407
GeneOntologyMolecularFunction	histone modifying activity	KAT5 HDAC4 KDM6A EP300	5.28e-03	229	61	4	GO:0140993
GeneOntologyMolecularFunction	zinc ion binding	TET2 HIVEP1 HDAC4 ZFHX3 GRIN2A EP300 ZFPM2 USP33	5.52e-03	891	61	8	GO:0008270
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	NFE2L3 BPTF ZBTB49 HNF1A HIVEP1 KAT5 HDAC4 MCPH1 NFATC2 RB1 ZFHX3 RUNX1 LMO4 EP300 ZFPM2 CDK6	5.65e-08	1053	62	16	GO:0000122
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	TET2 BPTF ZBTB49 NCOA6 HNF1A CRTC3 ZBTB38 HIVEP1 KAT5 HDAC4 NFATC2 RB1 ZFHX3 RUNX1 LMO4 KDM6A EP300 ZFPM2	7.88e-08	1390	62	18	GO:0045944
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	NFE2L3 BPTF ZBTB49 HNF1A ZBTB38 HIVEP1 KAT5 HDAC4 MCPH1 NFATC2 RB1 GON4L ZFHX3 RUNX1 LMO4 EP300 ZFPM2 CDK6	8.69e-08	1399	62	18	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	NFE2L3 BPTF ZBTB49 HNF1A ZBTB38 HIVEP1 KAT5 HDAC4 MCPH1 NFATC2 RB1 GON4L ZFHX3 RUNX1 LMO4 EP300 ZFPM2 CDK6	1.01e-07	1413	62	18	GO:1902679
GeneOntologyBiologicalProcess	chromatin remodeling	TET2 BPTF HNF1A ARID1B KAT5 HDAC4 RB1 KDM6A EP300 RAD54L	6.68e-05	741	62	10	GO:0006338
GeneOntologyBiologicalProcess	leukocyte differentiation	TET2 FASN ARID1B KAT5 HDAC4 RB1 GON4L RUNX1 EP300 CDK6	1.12e-04	789	62	10	GO:0002521
GeneOntologyBiologicalProcess	mononuclear cell differentiation	FASN ARID1B KAT5 HDAC4 RB1 GON4L RUNX1 EP300 CDK6	1.18e-04	640	62	9	GO:1903131
GeneOntologyBiologicalProcess	muscle structure development	ARID1B KAT5 HDAC4 NFATC2 RB1 NEURL1 LAMA2 ZFHX3 EP300 ZFPM2	2.22e-04	858	62	10	GO:0061061
GeneOntologyBiologicalProcess	positive regulation of collagen biosynthetic process	LARP6 RUNX1 EP300	2.54e-04	41	62	3	GO:0032967
GeneOntologyBiologicalProcess	positive regulation of collagen metabolic process	LARP6 RUNX1 EP300	3.14e-04	44	62	3	GO:0010714
GeneOntologyBiologicalProcess	chromatin organization	TET2 BPTF HNF1A ARID1B KAT5 HDAC4 RB1 KDM6A EP300 RAD54L	3.14e-04	896	62	10	GO:0006325
GeneOntologyBiologicalProcess	regulation of female gonad development	RUNX1 ZFPM2	3.16e-04	9	62	2	GO:2000194
GeneOntologyBiologicalProcess	muscle organ development	HDAC4 RB1 NEURL1 LAMA2 ZFHX3 EP300 ZFPM2	3.24e-04	436	62	7	GO:0007517
GeneOntologyBiologicalProcess	chordate embryonic development	BPTF NCOA6 HNF1A KAT5 KIAA1217 RUNX1 LMO4 KDM6A EP300 ZFPM2	3.43e-04	906	62	10	GO:0043009
GeneOntologyBiologicalProcess	regulation of purine nucleotide metabolic process	HNF1A HDAC4 ME1 EP300	3.61e-04	112	62	4	GO:1900542
GeneOntologyBiologicalProcess	regulation of nucleotide metabolic process	HNF1A HDAC4 ME1 EP300	3.73e-04	113	62	4	GO:0006140
GeneOntologyBiologicalProcess	regulation of NADP metabolic process	HNF1A ME1	3.94e-04	10	62	2	GO:1902031
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	BPTF NCOA6 HNF1A KAT5 KIAA1217 RUNX1 LMO4 KDM6A EP300 ZFPM2	4.18e-04	929	62	10	GO:0009792
GeneOntologyCellularComponent	transcription regulator complex	NFE2L3 NCOA6 HNF1A KAT5 HDAC4 DACH2 NFATC2 RB1 ZFHX3 RUNX1 LMO4 EP300	1.52e-07	596	62	12	GO:0005667
GeneOntologyCellularComponent	SWI/SNF superfamily-type complex	BPTF ARID1B KAT5 RB1 GON4L	9.67e-06	96	62	5	GO:0070603
GeneOntologyCellularComponent	chromatin	NFE2L3 BPTF HNF1A ARID1B KAT5 HDAC4 NFATC2 RB1 TLX3 GON4L ZFHX3 RUNX1 EP300 SLX4 ZFPM2	2.05e-05	1480	62	15	GO:0000785
GeneOntologyCellularComponent	nuclear protein-containing complex	NFE2L3 BPTF NCOA6 ARID1B KAT5 HDAC4 NFATC2 RB1 GON4L SNUPN RUNX1 LMO4 KDM6A SLX4	3.96e-05	1377	62	14	GO:0140513
GeneOntologyCellularComponent	ATPase complex	BPTF ARID1B KAT5 RB1 GON4L	4.04e-05	129	62	5	GO:1904949
GeneOntologyCellularComponent	MLL3/4 complex	NCOA6 KDM6A	5.60e-04	12	62	2	GO:0044666
GeneOntologyCellularComponent	RNA polymerase II transcription regulator complex	NFE2L3 NFATC2 RB1 RUNX1 LMO4	1.27e-03	272	62	5	GO:0090575
HumanPheno	Neoplasm by anatomical site	TET2 PTPN3 HNF1A ARID1B HDAC4 NFATC2 RB1 RUNX1 KDM6A EP300 SLX4 ZFPM2 RAD54L KRIT1	1.91e-05	959	24	14	HP:0011793
HumanPheno	Neoplasm	TET2 PTPN3 HNF1A ARID1B HDAC4 NFATC2 RB1 RUNX1 KDM6A EP300 SLX4 ZFPM2 RAD54L KRIT1	2.69e-05	987	24	14	HP:0002664
HumanPheno	Hematological neoplasm	TET2 ARID1B NFATC2 RB1 RUNX1 EP300 SLX4 RAD54L KRIT1	7.42e-05	424	24	9	HP:0004377
HumanPheno	Inheritance qualifier	TET2 HDAC4 RB1 GRIN2A RUNX1 EP300 RAD54L KRIT1	8.37e-05	330	24	8	HP:0034335
HumanPheno	Typified by somatic mosaicism	TET2 HDAC4 RB1 RUNX1 EP300 RAD54L	9.66e-05	168	24	6	HP:0001442
HumanPheno	Somatic mutation	TET2 HDAC4 RB1 RUNX1 EP300 RAD54L	9.66e-05	168	24	6	HP:0001428
Domain	p53-like_TF_DNA-bd	NFATC2 RUNX1 KRIT1	5.96e-04	53	58	3	IPR008967
Domain	-	ACLY SYN1	1.40e-03	18	58	2	3.30.470.20
Domain	-	PKNOX2 HNF1A TLX3 GON4L ZFHX3	1.83e-03	283	58	5	1.10.10.60
Domain	Bromodomain_CS	BPTF EP300	2.94e-03	26	58	2	IPR018359
Domain	Homeodomain-like	PKNOX2 HNF1A TLX3 GON4L ZFHX3	3.65e-03	332	58	5	IPR009057
Domain	ATP_grasp_subdomain_2	ACLY SYN1	4.16e-03	31	58	2	IPR013816
Domain	LRRCT	CPN2 ADGRA3	4.43e-03	32	58	2	PF01463
Domain	BROMODOMAIN_1	BPTF EP300	5.89e-03	37	58	2	PS00633
Domain	Homeobox	PKNOX2 HNF1A TLX3 ZFHX3	6.00e-03	234	58	4	PF00046
Domain	HOMEOBOX_1	PKNOX2 HNF1A TLX3 ZFHX3	6.18e-03	236	58	4	PS00027
Pathway	REACTOME_RUNX3_REGULATES_P14_ARF	HDAC4 RUNX1 EP300	3.13e-06	10	43	3	M27824
Pathway	PID_P73PATHWAY	FASN KAT5 RB1 EP300 CDK6	3.96e-06	79	43	5	M19
Pathway	KEGG_MEDICUS_REFERENCE_P300_P21_CELL_CYCLE_G1_S	RB1 EP300 CDK6	1.17e-05	15	43	3	M47524
Pathway	PID_ERA_GENOMIC_PATHWAY	HDAC4 AP1B1 LMO4 EP300	4.17e-05	64	43	4	M200
Pathway	WP_KLEEFSTRA_SYNDROME	NCOA6 ARID1B KDM6A	9.14e-05	29	43	3	M48076
Pathway	WP_TUMOR_SUPPRESSOR_ACTIVITY_OF_SMARCB1	ARID1B RB1 CDK6	1.12e-04	31	43	3	M39522
Pathway	WP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR	HDAC4 NFATC2 EP300	1.23e-04	32	43	3	M39521
Pathway	WP_CLEAR_CELL_RENAL_CELL_CARCINOMA_PATHWAYS	FASN ACLY ME1 EP300	1.33e-04	86	43	4	M39375
Pathway	REACTOME_RUNX3_REGULATES_P14_ARF	HDAC4 EP300	1.35e-04	6	43	2	MM15545
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VCYCLIN_TO_CELL_CYCLE_G1_S	RB1 CDK6	1.35e-04	6	43	2	M47461
Pathway	WP_CAMKK2_PATHWAY	HDAC4 NFATC2 EP300	1.35e-04	33	43	3	M40047
Pathway	REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN	ARID1B RUNX1 EP300	1.91e-04	37	43	3	M27797
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3	HDAC4 ZFHX3 RUNX1 EP300	2.03e-04	96	43	4	M27784
Pathway	BIOCARTA_MALATEX_PATHWAY	ACLY ME1	2.52e-04	8	43	2	M22038
Pathway	BIOCARTA_MALATEX_PATHWAY	ACLY ME1	2.52e-04	8	43	2	MM1558
Pathway	REACTOME_CHREBP_ACTIVATES_METABOLIC_GENE_EXPRESSION	FASN ACLY	2.52e-04	8	43	2	M26991
Pathway	WP_METABOLIC_REPROGRAMMING_IN_PANCREATIC_CANCER	FASN ACLY ME1	2.79e-04	42	43	3	M45531
Pathway	KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_CELL_CYCLE_G1_S_N00483	RB1 CDK6	3.23e-04	9	43	2	M49010
Pathway	REACTOME_RUNX1_AND_FOXP3_CONTROL_THE_DEVELOPMENT_OF_REGULATORY_T_LYMPHOCYTES_TREGS	NFATC2 RUNX1	4.03e-04	10	43	2	M27783
Pathway	KEGG_MEDICUS_REFERENCE_P16_CELL_CYCLE_G1_S	RB1 CDK6	4.03e-04	10	43	2	M47418
Pathway	REACTOME_HEME_SIGNALING	NCOA6 CRTC3 EP300	4.42e-04	49	43	3	M41832
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_CELL_CYCLE_G1_S	RB1 CDK6	4.91e-04	11	43	2	M47426
Pathway	BIOCARTA_PPARA_PATHWAY	RB1 ME1 EP300	5.26e-04	52	43	3	M2404
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_MDM2_TO_P21_CELL_CYCLE_G1_S	RB1 CDK6	5.88e-04	12	43	2	M47417
Pathway	KEGG_MEDICUS_REFERENCE_MDM2_P21_CELL_CYCLE_G1_S_N00066	RB1 CDK6	6.94e-04	13	43	2	M47416
Pathway	KEGG_MEDICUS_REFERENCE_P15_CELL_CYCLE_G1_S	RB1 CDK6	6.94e-04	13	43	2	M49035
Pathway	REACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER	HDAC4 NEURL1 EP300	7.26e-04	58	43	3	M29616
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1	ARID1B NFATC2 RUNX1 EP300 CDK6	7.36e-04	237	43	5	M27786
Pathway	PID_ATF2_PATHWAY	KAT5 RB1 EP300	7.63e-04	59	43	3	M166
Pathway	BIOCARTA_PITX2_PATHWAY	KAT5 EP300	9.31e-04	15	43	2	MM1439
Pathway	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION	TET2 NCOA6 ARID1B KDM6A EP300	1.00e-03	254	43	5	M27131
Pathway	PID_RB_1PATHWAY	RB1 EP300 CDK6	1.01e-03	65	43	3	M279
Pathway	BIOCARTA_MEF2D_PATHWAY	NFATC2 EP300	1.06e-03	16	43	2	MM1483
Pathway	BIOCARTA_PITX2_PATHWAY	KAT5 EP300	1.06e-03	16	43	2	M8516
Pathway	WP_MELANOMA	RB1 GRIN2A CDK6	1.15e-03	68	43	3	M39811
Pathway	REACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY	RUNX1 CDK6	1.20e-03	17	43	2	M27788
Pathway	REACTOME_ABERRANT_REGULATION_OF_MITOTIC_G1_S_TRANSITION_IN_CANCER_DUE_TO_RB1_DEFECTS	RB1 CDK6	1.20e-03	17	43	2	M38998
Pathway	REACTOME_CIRCADIAN_CLOCK	NCOA6 CRTC3 EP300	1.26e-03	70	43	3	M938
Pathway	BIOCARTA_MEF2D_PATHWAY	NFATC2 EP300	1.35e-03	18	43	2	M5290
Pathway	REACTOME_RORA_ACTIVATES_GENE_EXPRESSION	NCOA6 EP300	1.35e-03	18	43	2	M26942
Pathway	KEGG_CHRONIC_MYELOID_LEUKEMIA	RB1 RUNX1 CDK6	1.42e-03	73	43	3	M321
Pathway	REACTOME_SIGNALING_BY_NOTCH1	HDAC4 NEURL1 EP300	1.47e-03	74	43	3	M616
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3	HDAC4 ZFHX3 EP300	1.59e-03	76	43	3	MM15520
Pathway	WP_CALCIUM_MEDIATED_TCELL_APOPTOSIS_INVOLVED_IN_INCLUSION_BODY_MYOSITIS	NFATC2 EP300	1.67e-03	20	43	2	M48330
Pathway	WP_FATTY_ACID_BIOSYNTHESIS	FASN ACLY	2.02e-03	22	43	2	M39440
Pathway	WP_GLIOBLASTOMA_SIGNALING	RB1 EP300 CDK6	2.05e-03	83	43	3	M39637
Pathway	KEGG_SMALL_CELL_LUNG_CANCER	RB1 LAMA2 CDK6	2.12e-03	84	43	3	M3228
Pathway	PID_CMYB_PATHWAY	ZFHX3 EP300 CDK6	2.12e-03	84	43	3	M195
Pathway	BIOCARTA_CELLCYCLE_PATHWAY	RB1 CDK6	2.21e-03	23	43	2	M17770
Pathway	WP_FATTY_ACID_BIOSYNTHESIS	FASN ACLY	2.21e-03	23	43	2	MM15885
Pathway	BIOCARTA_CELLCYCLE_PATHWAY	RB1 CDK6	2.40e-03	24	43	2	MM1376
Pathway	WP_ANDROGEN_RECEPTOR_SIGNALING	KAT5 RB1 EP300	2.66e-03	91	43	3	M39700
Pathway	BIOCARTA_CARM_ER_PATHWAY	HDAC4 EP300	2.82e-03	26	43	2	M2499
Pathway	BIOCARTA_RACCYCD_PATHWAY	RB1 CDK6	2.82e-03	26	43	2	M14512
Pathway	BIOCARTA_RACCYCD_PATHWAY	RB1 CDK6	2.82e-03	26	43	2	MM1423
Pathway	PID_HDAC_CLASSIII_PATHWAY	HDAC4 EP300	2.82e-03	26	43	2	M32
Pathway	REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX	KAT5 EP300	2.82e-03	26	43	2	MM14793
Pathway	KEGG_PATHWAYS_IN_CANCER	RB1 LAMA2 RUNX1 EP300 CDK6	2.96e-03	325	43	5	M12868
Pathway	WP_SMALL_CELL_LUNG_CANCER	RB1 LAMA2 CDK6	3.10e-03	96	43	3	M39834
Pathway	BIOCARTA_G1_PATHWAY	RB1 CDK6	3.27e-03	28	43	2	M648
Pubmed	Interaction network of human early embryonic transcription factors.	TET2 BPTF NCOA6 ARID1B HIVEP1 KAT5 HDAC4 ZFHX3 LMO4 KDM6A EP300 SLX4	1.27e-12	351	62	12	38297188
Pubmed	Human transcription factor protein interaction networks.	TET2 BPTF NCOA6 HNF1A ARID1B HIVEP1 KAT5 RB1 ZNF592 TLX3 MARF1 GON4L ZFHX3 LMO4 KDM6A EP300 SLX4 ZFPM2	3.32e-11	1429	62	18	35140242
Pubmed	CDK6-mediated repression of CD25 is required for induction and maintenance of Notch1-induced T-cell acute lymphoblastic leukemia.	RB1 RUNX1 CDK6	2.16e-08	4	62	3	26707936
Pubmed	T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities.	NFE2L3 NCOA6 KAT5 EP300	4.34e-08	20	62	4	11877444
Pubmed	Two ZNF509 (ZBTB49) isoforms induce cell-cycle arrest by activating transcription of p21/CDKN1A and RB upon exposure to genotoxic stress.	ZBTB49 KAT5 EP300	5.38e-08	5	62	3	25245946
Pubmed	A census of human transcription factors: function, expression and evolution.	NFE2L3 PKNOX2 HNF1A ZBTB38 HIVEP1 DACH2 NFATC2 TLX3 GON4L ZFHX3 RUNX1 ZFPM2	6.08e-08	908	62	12	19274049
Pubmed	Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation.	DACH2 RUNX1 EP300	1.07e-07	6	62	3	16917507
Pubmed	Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.	HDAC4 SYN1 GRIN2A EP300	1.81e-07	28	62	4	31600191
Pubmed	p300 is required for orderly G1/S transition in human cancer cells.	RB1 EP300 CDK6	1.88e-07	7	62	3	16878158
Pubmed	NEDDylation controls the target specificity of E2F1 and apoptosis induction.	MCPH1 RB1 EP300	3.00e-07	8	62	3	23001041
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	BPTF NCOA6 ARID1B KDM6A EP300	3.98e-07	83	62	5	28794006
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TET2 BPTF NCOA6 FASN ARID1B HIVEP1 HDAC4 AP1B1 ACLY RUNX1 KDM6A EP300	4.88e-07	1103	62	12	34189442
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	TET2 ARID1B HIVEP1 RB1 GON4L KDM6A EP300 ZFPM2	5.41e-07	398	62	8	35016035
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NFE2L3 TET2 ZBTB38 LARP6 ZNF592 RUNX1 LMO4 KDM6A EP300 SLX4 USP33 KRIT1	2.40e-06	1285	62	12	35914814
Pubmed	CDK6 inhibits white to beige fat transition by suppressing RUNX1.	RUNX1 CDK6	3.13e-06	2	62	2	29523786
Pubmed	Regulation of neuronal gene expression and survival by basal NMDA receptor activity: a role for histone deacetylase 4.	HDAC4 GRIN2A	3.13e-06	2	62	2	25392500
Pubmed	Whole transcriptome sequencing of a paediatric case of de novo acute myeloid leukaemia with del(5q) reveals RUNX1-USP42 and PRDM16-SKI fusion transcripts.	USP42 RUNX1	3.13e-06	2	62	2	24673627
Pubmed	FOG-2 competes with GATA-4 for transcriptional coactivator p300 and represses hypertrophic responses in cardiac myocytes.	EP300 ZFPM2	3.13e-06	2	62	2	15220332
Pubmed	P300 acetyltransferase regulates fatty acid synthase expression, lipid metabolism and prostate cancer growth.	FASN EP300	3.13e-06	2	62	2	26934656
Pubmed	Tip60 and p300 function antagonistically in the epigenetic regulation of HPV18 E6/E7 genes in cervical cancer HeLa cells.	KAT5 EP300	3.13e-06	2	62	2	32399935
Pubmed	Acquired TET2 mutation in one patient with familial platelet disorder with predisposition to AML led to the development of pre-leukaemic clone resulting in T2-ALL and AML-M0.	TET2 RUNX1	3.13e-06	2	62	2	27997762
Pubmed	Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior.	ARID1B KAT5 HDAC4 EP300	3.14e-06	56	62	4	29184203
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	PKNOX2 HNF1A KAT5 HDAC4 DACH2 RB1 ZNF592 TLX3 LMO4 EP300	3.24e-06	877	62	10	20211142
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	BPTF FASN AP1B1 NFATC2 RUNX1 KRIT1 CDK6	4.34e-06	370	62	7	22922362
Pubmed	Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.	HDAC4 NEURL1 GRIN2A ZFPM2	5.71e-06	65	62	4	23453885
Pubmed	Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.	HIVEP1 KAT5 KDM6A EP300	7.26e-06	69	62	4	32238831
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	BPTF ARID1B KAT5 ZNF592 GON4L	7.41e-06	150	62	5	28242625
Pubmed	Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.	RB1 RUNX1 KDM6A CDK6	8.13e-06	71	62	4	28319113
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	BPTF NCOA6 FASN HIVEP1 USP42 ZNF592 ACLY RUNX1 KDM6A	9.04e-06	774	62	9	15302935
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	BPTF NCOA6 ARID1B HDAC4 EP300	9.25e-06	157	62	5	30186101
Pubmed	Mutually exclusive mutation profiles define functionally related genes in muscle invasive bladder cancer.	RB1 KDM6A	9.37e-06	3	62	2	35073341
Pubmed	A histone deacetylase 4/myogenin positive feedback loop coordinates denervation-dependent gene induction and suppression.	HDAC4 DACH2	9.37e-06	3	62	2	19109424
Pubmed	Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL.	TLX3 RUNX1	9.37e-06	3	62	2	22366949
Pubmed	TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression.	RB1 CDK6	9.37e-06	3	62	2	18305152
Pubmed	The KDM6A-KMT2D-p300 axis regulates susceptibility to diverse coronaviruses by mediating viral receptor expression.	KDM6A EP300	9.37e-06	3	62	2	37410700
Pubmed	Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60.	KAT5 EP300	9.37e-06	3	62	2	24835996
Pubmed	Transcriptional coactivators CBP and p300 cooperatively enhance HNF-1alpha-mediated expression of the albumin gene in hepatocytes.	HNF1A EP300	9.37e-06	3	62	2	15598887
Pubmed	Interactions between activating signal cointegrator-2 and the tumor suppressor retinoblastoma in androgen receptor transactivation.	NCOA6 RB1	9.37e-06	3	62	2	14645241
Pubmed	AML1-FOG2 fusion protein in myelodysplasia.	RUNX1 ZFPM2	9.37e-06	3	62	2	15705784
Pubmed	RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer.	RB1 RUNX1	9.37e-06	3	62	2	26916619
Pubmed	BCAT2 promotes melanoma progression by activating lipogenesis via the epigenetic regulation of FASN and ACLY expressions.	FASN ACLY	9.37e-06	3	62	2	37801083
Pubmed	Identification of p300-targeted acetylated residues in GATA4 during hypertrophic responses in cardiac myocytes.	EP300 ZFPM2	9.37e-06	3	62	2	18252717
Pubmed	Hepatocyte nuclear factor-1alpha recruits the transcriptional co-activator p300 on the GLUT2 gene promoter.	HNF1A EP300	9.37e-06	3	62	2	11978637
Pubmed	The tumor suppressor Rb and its related Rbl2 genes are regulated by Utx histone demethylase.	RB1 KDM6A	9.37e-06	3	62	2	20650264
Pubmed	HDAC4 degradation during senescence unleashes an epigenetic program driven by AP-1/p300 at selected enhancers and super-enhancers.	HDAC4 EP300	9.37e-06	3	62	2	33966634
Pubmed	Secretion of three enzymes for fatty acid synthesis into mouse milk in association with fat globules, and rapid decrease of the secreted enzymes by treatment with rapamycin.	FASN ACLY	9.37e-06	3	62	2	21281598
Pubmed	BCKDHA contributes to melanoma progression by promoting the expressions of lipogenic enzymes FASN and ACLY.	FASN ACLY	9.37e-06	3	62	2	37377173
Pubmed	Direct suppression of Stat1 function during adenoviral infection.	RB1 EP300	9.37e-06	3	62	2	9881977
Pubmed	A novel Rb- and p300-binding protein inhibits transactivation by MyoD.	RB1 EP300	9.37e-06	3	62	2	11073990
Pubmed	The lipogenesis pathway as a cancer target.	FASN ACLY	9.37e-06	3	62	2	21726077
Pubmed	HIV-1 Tat targets Tip60 to impair the apoptotic cell response to genotoxic stresses.	KAT5 EP300	9.37e-06	3	62	2	16001085
Pubmed	Nuclear factor of activated T cells (NFAT)-dependent transactivation regulated by the coactivators p300/CREB-binding protein (CBP).	NFATC2 EP300	9.37e-06	3	62	2	9625762
Pubmed	The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation.	RUNX1 EP300	9.37e-06	3	62	2	21764752
Pubmed	ZNF509S1 downregulates PUMA by inhibiting p53K382 acetylation and p53-DNA binding.	ZBTB49 EP300	9.37e-06	3	62	2	28757384
Pubmed	Cyclin-dependent kinase phosphorylation of RUNX1/AML1 on 3 sites increases transactivation potency and stimulates cell proliferation.	RUNX1 CDK6	9.37e-06	3	62	2	18003885
Pubmed	A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription.	KDM6A EP300	9.37e-06	3	62	2	28732206
Pubmed	Distinct and nonoverlapping roles for pRB and cyclin D:cyclin-dependent kinases 4/6 activity in melanocyte survival.	RB1 CDK6	9.37e-06	3	62	2	14630948
Pubmed	Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells.	RB1 CDK6	9.37e-06	3	62	2	20100483
Pubmed	Functional proteomics mapping of a human signaling pathway.	NCOA6 ARID1B HIVEP1 AP1B1 ZNF592 LMO4 KDM6A SDK1	1.00e-05	591	62	8	15231748
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	NCOA6 FASN ATP8A1 AP1B1 ACLY SYN1 GRIN2A KDM6A	1.43e-05	621	62	8	22794259
Pubmed	NRF3-POMP-20S Proteasome Assembly Axis Promotes Cancer Development via Ubiquitin-Independent Proteolysis of p53 and Retinoblastoma Protein.	NFE2L3 RB1	1.87e-05	4	62	2	32123008
Pubmed	Molecular similarity between myelodysplastic form of chronic myelomonocytic leukemia and refractory anemia with ring sideroblasts.	TET2 RUNX1	1.87e-05	4	62	2	23065512
Pubmed	Murine leukemia retrovirus integration induces the formation of transcription factor complexes on palindromic sequences in the signal transducer and activator of transcription factor 5a gene during the development of pre-B lymphomagenesis.	RUNX1 EP300	1.87e-05	4	62	2	21356387
Pubmed	HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer.	HNF1A KDM6A	1.87e-05	4	62	2	32154941
Pubmed	Cdk6 blocks myeloid differentiation by interfering with Runx1 DNA binding and Runx1-C/EBPalpha interaction.	RUNX1 CDK6	1.87e-05	4	62	2	17431401
Pubmed	Transcription factor FOXA3 promotes the development of Hepatoblastoma via regulating HNF1A, AFP, and ZFHX3 expression.	HNF1A ZFHX3	1.87e-05	4	62	2	33368532
Pubmed	Array comparative genome hybridization for tumor classification and gene discovery in mouse models of malignant melanoma.	KRIT1 CDK6	1.87e-05	4	62	2	14500367
Pubmed	Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis.	KAT5 EP300	1.87e-05	4	62	2	17189186
Pubmed	Hepatitis C virus core protein regulates p300/CBP co-activation function. Possible role in the regulation of NF-AT1 transcriptional activity.	NFATC2 EP300	1.87e-05	4	62	2	15380363
Pubmed	Overexpression of RUNX3 Represses RUNX1 to Drive Transformation of Myelodysplastic Syndrome.	TET2 RUNX1	1.87e-05	4	62	2	32341038
Pubmed	The adenovirus E1A oncoprotein recruits the cellular TRRAP/GCN5 histone acetyltransferase complex.	RB1 EP300	1.87e-05	4	62	2	12743606
Pubmed	Expression of p16 and retinoblastoma determines response to CDK4/6 inhibition in ovarian cancer.	RB1 CDK6	1.87e-05	4	62	2	21278246
Pubmed	The Rb-CDK4/6 signaling pathway is critical in neural precursor cell cycle regulation.	RB1 CDK6	1.87e-05	4	62	2	10915795
Pubmed	Overexpression of Cdk6 and Ccnd1 in chondrocytes inhibited chondrocyte maturation and caused p53-dependent apoptosis without enhancing proliferation.	RB1 CDK6	1.87e-05	4	62	2	23624920
Pubmed	Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein.	RB1 EP300	1.87e-05	4	62	2	19651603
Pubmed	Transcriptional coactivator PRIP, the peroxisome proliferator-activated receptor gamma (PPARgamma)-interacting protein, is required for PPARgamma-mediated adipogenesis.	NCOA6 EP300	1.87e-05	4	62	2	12754253
Pubmed	Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle.	RB1 EP300	1.87e-05	4	62	2	11073989
Pubmed	Oligomers of human histone chaperone NPM1 alter p300/KAT3B folding to induce autoacetylation.	KAT5 EP300	1.87e-05	4	62	2	29746960
Pubmed	Targeting the RB-E2F pathway in breast cancer.	RB1 CDK6	1.87e-05	4	62	2	26923330
Pubmed	High glucose mediates the ChREBP/p300 transcriptional complex to activate proapoptotic genes Puma and BAX and contributes to intervertebral disc degeneration.	FASN KAT5 EP300	1.91e-05	29	62	3	34461288
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TET2 NCOA6 PTPN3 CRTC3 HIVEP1 HDAC4 KIAA1217 NEURL1 MPHOSPH9	2.10e-05	861	62	9	36931259
Pubmed	A human MAP kinase interactome.	PTPN3 CRTC3 HIVEP1 HDAC4 MPHOSPH9 LMO4 EP300	2.52e-05	486	62	7	20936779
Pubmed	Cross-Species Genomics Identifies TAF12, NFYC, and RAD54L as Choroid Plexus Carcinoma Oncogenes.	RB1 RAD54L	3.12e-05	5	62	2	25965574
Pubmed	Physical interaction of human T-cell leukemia virus type 1 Tax with cyclin-dependent kinase 4 stimulates the phosphorylation of retinoblastoma protein.	RB1 CDK6	3.12e-05	5	62	2	11971966
Pubmed	Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins.	RB1 EP300	3.12e-05	5	62	2	1331501
Pubmed	KIX domain determines a selective tumor-promoting role for EP300 and its vulnerability in small cell lung cancer.	RB1 EP300	3.12e-05	5	62	2	35171684
Pubmed	6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site.	KAT5 EP300	3.12e-05	5	62	2	22100137
Pubmed	Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization.	KAT5 EP300	3.12e-05	5	62	2	19996091
Pubmed	SUMO1 modification stabilizes CDK6 protein and drives the cell cycle and glioblastoma progression.	RB1 CDK6	3.12e-05	5	62	2	24953629
Pubmed	Transcriptional activation of hypoxia-inducible factor-1alpha by HDAC4 and HDAC5 involves differential recruitment of p300 and FIH-1.	HDAC4 EP300	3.12e-05	5	62	2	19071119
Pubmed	Recruitment of histone deacetylase 4 by transcription factors represses interleukin-5 transcription.	HDAC4 EP300	3.12e-05	5	62	2	16922677
Pubmed	Knockdown of protein tyrosine phosphatase SHP-1 inhibits G1/S progression in prostate cancer cells through the regulation of components of the cell-cycle machinery.	RB1 CDK6	3.12e-05	5	62	2	19838216
Pubmed	PROSER1 mediates TET2 O-GlcNAcylation to regulate DNA demethylation on UTX-dependent enhancers and CpG islands.	TET2 KDM6A	3.12e-05	5	62	2	34667079
Pubmed	The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming.	HDAC4 DACH2	3.12e-05	5	62	2	17873280
Pubmed	Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program.	FASN ACLY	3.12e-05	5	62	2	37163372
Pubmed	Phosphorylation of von Hippel-Lindau protein by checkpoint kinase 2 regulates p53 transactivation.	KAT5 EP300	3.12e-05	5	62	2	22071692
Pubmed	Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor gamma-dependent repression of cyclin D1.	RB1 EP300	3.12e-05	5	62	2	11287611
Pubmed	The retinoblastoma-histone deacetylase 3 complex inhibits PPARgamma and adipocyte differentiation.	RB1 EP300	3.12e-05	5	62	2	12479814
Pubmed	The high-risk HPV16 E7 oncoprotein mediates interaction between the transcriptional coactivator CBP and the retinoblastoma protein pRb.	RB1 EP300	3.12e-05	5	62	2	25451029
Pubmed	Knockdown of Fbxo7 reveals its regulatory role in proliferation and differentiation of haematopoietic precursor cells.	RB1 CDK6	3.12e-05	5	62	2	21652635
Interaction	EGR2 interactions	TET2 NCOA6 ARID1B HIVEP1 HDAC4 ZFHX3 LMO4 KDM6A EP300	2.19e-09	171	61	9	int:EGR2
Interaction	CREBBP interactions	NCOA6 HNF1A ARID1B HIVEP1 KAT5 AP1B1 NFATC2 RB1 ZNF592 MARF1 RUNX1 KDM6A EP300 SLX4	2.24e-09	599	61	14	int:CREBBP
Interaction	HNF1B interactions	TET2 BPTF HNF1A ARID1B HIVEP1 TLX3 ZFHX3 KDM6A EP300	5.53e-09	190	61	9	int:HNF1B
Interaction	MYOD1 interactions	BPTF ARID1B HIVEP1 KAT5 RB1 RUNX1 LMO4 KDM6A EP300	6.64e-09	194	61	9	int:MYOD1
Interaction	GATA2 interactions	NCOA6 FASN ARID1B HIVEP1 ZFHX3 RUNX1 KDM6A EP300 ZFPM2	8.29e-09	199	61	9	int:GATA2
Interaction	HNF4A interactions	BPTF NCOA6 HNF1A ARID1B HIVEP1 KAT5 HDAC4 KDM6A EP300 SLX4	9.29e-09	275	61	10	int:HNF4A
Interaction	ERG interactions	TET2 NCOA6 ARID1B HIVEP1 SYN1 LMO4 KDM6A EP300 SLX4	2.23e-08	223	61	9	int:ERG
Interaction	PPARG interactions	NFE2L3 NCOA6 ARID1B HIVEP1 KAT5 HDAC4 RB1 LMO4 KDM6A EP300	2.64e-08	307	61	10	int:PPARG
Interaction	AR interactions	TET2 NCOA6 ARID1B HIVEP1 KAT5 HDAC4 RB1 ACLY KIAA1217 TLX3 ZFHX3 RUNX1 ME1 KDM6A EP300 CDK6	2.64e-08	992	61	16	int:AR
Interaction	GCM1 interactions	TET2 ARID1B HIVEP1 HDAC4 KDM6A EP300	5.65e-08	68	61	6	int:GCM1
Interaction	FOS interactions	NCOA6 HNF1A ARID1B HIVEP1 NFATC2 RB1 RUNX1 KDM6A EP300	3.90e-07	312	61	9	int:FOS
Interaction	FOXP3 interactions	BPTF FASN KAT5 HDAC4 AP1B1 NFATC2 RUNX1 EP300 KRIT1 CDK6	6.27e-07	432	61	10	int:FOXP3
Interaction	CRX interactions	TET2 ARID1B KAT5 TLX3 ZFHX3 LMO4 KDM6A EP300	9.43e-07	254	61	8	int:CRX
Interaction	YY1 interactions	BPTF FASN HIVEP1 KAT5 HDAC4 RB1 ZNF592 GON4L EP300 SLX4	9.84e-07	454	61	10	int:YY1
Interaction	TEAD1 interactions	BPTF FASN ARID1B HIVEP1 ZFHX3 KDM6A EP300	1.01e-06	176	61	7	int:TEAD1
Interaction	PAX8 interactions	TET2 ARID1B HIVEP1 RB1 KDM6A EP300	1.06e-06	111	61	6	int:PAX8
Interaction	SMARCA4 interactions	BPTF HNF1A ARID1B MCPH1 NFATC2 RB1 RUNX1 KDM6A EP300 SLX4	1.15e-06	462	61	10	int:SMARCA4
Interaction	TBR1 interactions	TET2 ARID1B HIVEP1 ZFHX3 KDM6A EP300	1.17e-06	113	61	6	int:TBR1
Interaction	PAXIP1 interactions	NCOA6 HNF1A FASN TLX3 RUNX1 TRAPPC8 KDM6A EP300 SLX4	1.25e-06	359	61	9	int:PAXIP1
Interaction	E2F1 interactions	NCOA6 ARID1B KAT5 MCPH1 RB1 EP300 RAD54L	2.37e-06	200	61	7	int:E2F1
Interaction	TLX3 interactions	TET2 NCOA6 ARID1B HIVEP1 TLX3 ZFHX3 KDM6A EP300	2.60e-06	291	61	8	int:TLX3
Interaction	CEBPA interactions	TET2 BPTF NCOA6 HNF1A FASN ARID1B HIVEP1 KAT5 HDAC4 AP1B1 RB1 ACLY RUNX1 KDM6A EP300	3.19e-06	1245	61	15	int:CEBPA
Interaction	SIRT1 interactions	HNF1A FASN ZBTB38 KAT5 HDAC4 RB1 EP300 SLX4 CDK6	3.87e-06	412	61	9	int:SIRT1
Interaction	SRF interactions	BPTF NCOA6 HIVEP1 KAT5 HDAC4 KDM6A	3.93e-06	139	61	6	int:SRF
Interaction	HDAC1 interactions	TET2 BPTF FASN HIVEP1 KAT5 NFATC2 RB1 ZNF592 GON4L ZFHX3 RUNX1 LMO4 EP300 ZFPM2	4.21e-06	1108	61	14	int:HDAC1
Interaction	SOX7 interactions	TET2 ARID1B KDM6A EP300 ZFPM2	4.90e-06	82	61	5	int:SOX7
Interaction	NFIX interactions	BPTF ARID1B HIVEP1 RB1 TLX3 ZFHX3 KDM6A	5.46e-06	227	61	7	int:NFIX
Interaction	IRF4 interactions	ARID1B NFATC2 TLX3 KDM6A EP300	5.86e-06	85	61	5	int:IRF4
Interaction	GSC interactions	ARID1B HIVEP1 ZFHX3 KDM6A EP300	6.57e-06	87	61	5	int:GSC
Interaction	SMAD3 interactions	BPTF NCOA6 ARID1B HIVEP1 HDAC4 ZFHX3 RUNX1 EP300 USP33	7.48e-06	447	61	9	int:SMAD3
Interaction	SOX10 interactions	ARID1B HIVEP1 KDM6A EP300 CDK6	8.64e-06	92	61	5	int:SOX10
Interaction	ASF1A interactions	NCOA6 FASN ARID1B HIVEP1 HDAC4 ZNF592 EP300	9.98e-06	249	61	7	int:ASF1A
Interaction	GATA1 interactions	ARID1B HDAC4 RUNX1 KDM6A EP300 ZFPM2	1.29e-05	171	61	6	int:GATA1
Interaction	PAX6 interactions	BPTF NCOA6 ARID1B HIVEP1 RB1 ZFHX3 KDM6A EP300	1.39e-05	366	61	8	int:PAX6
Interaction	MED23 interactions	NCOA6 KAT5 RB1 ZNF592 ZFHX3 EP300 SLX4	1.53e-05	266	61	7	int:MED23
Interaction	NUP43 interactions	BPTF NCOA6 ARID1B HIVEP1 ATP8A1 ZNF592 MARF1 GON4L ZFHX3 SLX4	1.66e-05	625	61	10	int:NUP43
Interaction	TLE3 interactions	TET2 CRTC3 ARID1B HIVEP1 TLX3 ZFHX3 RUNX1 EP300	1.69e-05	376	61	8	int:TLE3
Interaction	GATA3 interactions	ARID1B HIVEP1 HDAC4 KDM6A EP300 ZFPM2	2.14e-05	187	61	6	int:GATA3
Interaction	LDB1 interactions	RB1 TLX3 ZFHX3 LMO4 EP300	2.56e-05	115	61	5	int:LDB1
Interaction	TBXT interactions	NCOA6 ARID1B HIVEP1 KDM6A EP300	2.67e-05	116	61	5	int:TBXT
Interaction	KLF5 interactions	TET2 NCOA6 ARID1B HIVEP1 KDM6A EP300	2.71e-05	195	61	6	int:KLF5
Interaction	CTBP1 interactions	HDAC4 NFATC2 RB1 MARF1 GRIN2A RUNX1 EP300 ZFPM2	2.93e-05	406	61	8	int:CTBP1
Interaction	TP53BP1 interactions	NCOA6 FASN ARID1B HDAC4 MCPH1 NFATC2 TLX3 EP300 SLX4	3.02e-05	533	61	9	int:TP53BP1
Interaction	RING1 interactions	ZBTB38 RB1 TLX3 RUNX1 ME1 EP300	3.21e-05	201	61	6	int:RING1
Interaction	ETS1 interactions	BPTF ARID1B HIVEP1 KDM6A EP300	3.27e-05	121	61	5	int:ETS1
Interaction	RBL1 interactions	RB1 TLX3 MARF1 EP300 CDK6	3.27e-05	121	61	5	int:RBL1
Interaction	FEV interactions	NCOA6 ARID1B HIVEP1 ZFHX3 KDM6A EP300	3.40e-05	203	61	6	int:FEV
Interaction	PAX7 interactions	ARID1B HIVEP1 ZFHX3 KDM6A EP300	3.67e-05	124	61	5	int:PAX7
Interaction	IL1A interactions	BPTF KAT5 EP300	3.90e-05	22	61	3	int:IL1A
Interaction	NFIC interactions	TET2 ARID1B ZBTB38 HIVEP1 TLX3 KDM6A	4.11e-05	210	61	6	int:NFIC
Interaction	VDR interactions	NCOA6 PTPN3 RB1 RUNX1 EP300	4.12e-05	127	61	5	int:VDR
Interaction	HDAC3 interactions	ARID1B KAT5 HDAC4 RB1 TLX3 RUNX1 EP300	4.34e-05	313	61	7	int:HDAC3
Interaction	RBPJL interactions	RB1 TLX3 EP300	4.48e-05	23	61	3	int:RBPJL
Interaction	PAX9 interactions	NCOA6 ARID1B ZFHX3 KDM6A EP300	4.60e-05	130	61	5	int:PAX9
Interaction	HIF1A interactions	FASN KAT5 HDAC4 RB1 TLX3 RUNX1 EP300 CDK6	5.26e-05	441	61	8	int:HIF1A
Interaction	KMT2C interactions	NCOA6 HNF1A FASN TLX3 KDM6A	5.32e-05	134	61	5	int:KMT2C
Interaction	STAT3 interactions	HNF1A ARID1B HIVEP1 KAT5 RB1 ZFHX3 EP300 ZFPM2	5.70e-05	446	61	8	int:STAT3
Interaction	ALX1 interactions	ZBTB38 KAT5 EP300	5.79e-05	25	61	3	int:ALX1
Interaction	KEAP1 interactions	TET2 BPTF FASN RB1 EP300 SLX4 CDK6	6.29e-05	332	61	7	int:KEAP1
Interaction	KLF3 interactions	BPTF ARID1B HIVEP1 ZFHX3 KDM6A EP300	6.48e-05	228	61	6	int:KLF3
Interaction	NCOA6 interactions	NCOA6 RB1 TLX3 KDM6A EP300	7.74e-05	145	61	5	int:NCOA6
Interaction	SUV39H1 interactions	FASN HDAC4 NFATC2 RB1 RUNX1 EP300	8.22e-05	238	61	6	int:SUV39H1
Interaction	CDK5 interactions	FASN HDAC4 RB1 SYN1 GRIN2A CDK6	9.01e-05	242	61	6	int:CDK5
Interaction	ZBTB49 interactions	ZBTB49 KAT5 EP300	9.12e-05	29	61	3	int:ZBTB49
Interaction	KPNA3 interactions	BPTF KAT5 HDAC4 USP42 RB1 SLX4	1.03e-04	248	61	6	int:KPNA3
Interaction	NCOR1 interactions	BPTF HDAC4 RB1 TLX3 RUNX1 EP300 SLX4	1.10e-04	363	61	7	int:NCOR1
Interaction	KLF4 interactions	ARID1B HIVEP1 KAT5 KDM6A EP300	1.23e-04	160	61	5	int:KLF4
Interaction	EDC3 interactions	FASN HDAC4 MARF1 EP300 SLX4	1.27e-04	161	61	5	int:EDC3
Interaction	PAX2 interactions	ARID1B HIVEP1 RB1 KDM6A	1.28e-04	85	61	4	int:PAX2
Interaction	CDX2 interactions	BPTF HNF1A ZNF592 EP300	1.34e-04	86	61	4	int:CDX2
Interaction	DLL4 interactions	FASN NEURL1	1.34e-04	6	61	2	int:DLL4
Interaction	MEF2D interactions	HDAC4 NFATC2 EP300 CDK6	1.40e-04	87	61	4	int:MEF2D
Interaction	WDR70 interactions	BPTF PTPN3 HDAC4 SLX4	1.40e-04	87	61	4	int:WDR70
Interaction	NHLH1 interactions	BPTF HIVEP1 LMO4 KDM6A	1.46e-04	88	61	4	int:NHLH1
Interaction	POGZ interactions	HNF1A HIVEP1 NFATC2 TLX3 SLX4 CDK6	1.48e-04	265	61	6	int:POGZ
Interaction	SMAD2 interactions	BPTF NCOA6 ARID1B HDAC4 AP1B1 RUNX1 EP300	1.58e-04	385	61	7	int:SMAD2
Interaction	KMT2D interactions	NCOA6 HNF1A TLX3 KDM6A EP300	1.59e-04	169	61	5	int:KMT2D
Interaction	ERI1 interactions	FASN SYN1 EP300	1.61e-04	35	61	3	int:ERI1
Interaction	CCND3 interactions	FASN RB1 RUNX1 CDK6	1.67e-04	91	61	4	int:CCND3
Interaction	HCFC2 interactions	NFE2L3 NCOA6 FASN KDM6A	1.74e-04	92	61	4	int:HCFC2
Interaction	FOXI1 interactions	FASN ARID1B KDM6A EP300	1.74e-04	92	61	4	int:FOXI1
Interaction	E2F5 interactions	ARID1B RB1 EP300	1.75e-04	36	61	3	int:E2F5
Interaction	EPAS1 interactions	ARID1B RB1 ZFHX3 EP300 USP33	1.77e-04	173	61	5	int:EPAS1
Interaction	RERE interactions	FASN TLX3 KDM6A EP300	1.81e-04	93	61	4	int:RERE
Interaction	TAL1 interactions	HIVEP1 RB1 RUNX1 EP300	1.81e-04	93	61	4	int:TAL1
Interaction	ARID1A interactions	BPTF ARID1B NFATC2 TLX3 RUNX1 EP300	1.85e-04	276	61	6	int:ARID1A
Interaction	TLX1 interactions	ARID1B HIVEP1 ZFHX3 KDM6A EP300	1.87e-04	175	61	5	int:TLX1
Interaction	POU2F1 interactions	HNF1A FASN HIVEP1 TLX3 ZFHX3	1.87e-04	175	61	5	int:POU2F1
Interaction	CRAMP1 interactions	FASN GON4L USP33	1.91e-04	37	61	3	int:CRAMP1
Interaction	MTA1 interactions	BPTF NFATC2 RUNX1 LMO4 EP300 ZFPM2	2.11e-04	283	61	6	int:MTA1
Interaction	SOX9 interactions	NCOA6 ARID1B KDM6A EP300	2.13e-04	97	61	4	int:SOX9
Interaction	SAP130 interactions	TET2 BPTF HNF1A RB1 SYN1	2.19e-04	181	61	5	int:SAP130
Interaction	ACTL6A interactions	ARID1B KAT5 NFATC2 RUNX1 EP300 SLX4	2.37e-04	289	61	6	int:ACTL6A
Interaction	EP300 interactions	ZBTB49 NCOA6 HNF1A FASN KAT5 AP1B1 NFATC2 RB1 ACLY TLX3 RUNX1 EP300 ZFPM2	2.37e-04	1401	61	13	int:EP300
Interaction	HCFC1 interactions	NFE2L3 NCOA6 ZBTB38 RUNX1 KDM6A SLX4	2.55e-04	293	61	6	int:HCFC1
Interaction	SALL1 interactions	FASN DACH2 TLX3 SLX4	2.59e-04	102	61	4	int:SALL1
Interaction	NFIA interactions	ARID1B HIVEP1 TLX3 KDM6A EP300	2.61e-04	188	61	5	int:NFIA
Interaction	MBD3 interactions	PKNOX2 TET2 BPTF FASN NFATC2 RUNX1	2.64e-04	295	61	6	int:MBD3
Interaction	WWTR1 interactions	BPTF NCOA6 ARID1B RB1 RUNX1 KDM6A EP300	2.77e-04	422	61	7	int:WWTR1
Interaction	GABPB1 interactions	FASN LMO4 EP300	2.99e-04	43	61	3	int:GABPB1
GeneFamily	Zinc fingers C2HC-type\|PHD finger proteins\|Lysine acetyltransferases	KAT5 ZFPM2	6.80e-04	16	44	2	66
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	KAT5 EP300	7.69e-04	17	44	2	486
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	ZBTB49 ZBTB38 SLX4	4.22e-03	134	44	3	861
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	PTPN3 KRIT1	6.58e-03	50	44	2	1293
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZBTB49 ZBTB38 HIVEP1 ZNF592 ZFHX3 ZFPM2	7.49e-03	718	44	6	28
GeneFamily	Ubiquitin specific peptidases	USP42 USP33	8.20e-03	56	44	2	366
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	TET2 BPTF SPRY3 FASN ATP8A1 RB1 LMO4 EP300	1.04e-08	180	62	8	M8239
Coexpression	IVANOVA_HEMATOPOIESIS_STEM_CELL_SHORT_TERM	BPTF NCOA6 MPHOSPH9	1.88e-05	22	62	3	M14523
Coexpression	IVANOVA_HEMATOPOIESIS_STEM_CELL_SHORT_TERM	BPTF NCOA6 MPHOSPH9	1.88e-05	22	62	3	MM676
Coexpression	HORTON_SREBF_TARGETS	FASN ACLY ME1	2.46e-05	24	62	3	MM1329
Coexpression	HORTON_SREBF_TARGETS	FASN ACLY ME1	2.46e-05	24	62	3	M3009
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	BPTF HIVEP1 HDAC4 RB1 ZFHX3 MPHOSPH9 RUNX1 TRAPPC8 ADGRA3 KRIT1	3.02e-05	856	62	10	M4500
Coexpression	GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_UP	ATP8A1 MCPH1 NEURL1 MARF1 GON4L	9.93e-05	195	62	5	M3184
Coexpression	GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_UP	BPTF CRTC3 ATP8A1 MARF1 KDM6A	1.07e-04	198	62	5	M3249
Coexpression	GSE8621_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN	CRTC3 ACLY MARF1 MPHOSPH9 KRIT1	1.09e-04	199	62	5	M6971
Coexpression	GSE13306_LAMINA_PROPRIA_VS_SPLEEN_TREG_DN	MS4A18 MCPH1 NFATC2 SNUPN CC2D2B	1.12e-04	200	62	5	M3219
Coexpression	GSE8515_CTRL_VS_IL6_4H_STIM_MAC_UP	BPTF SNUPN KDM6A ZFPM2 CACNA2D3	1.12e-04	200	62	5	M5763
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	BPTF HIVEP1 RB1 MARF1 RUNX1 TRAPPC8 KRIT1	1.14e-04	466	62	7	M13522
Coexpression	GRESHOCK_CANCER_COPY_NUMBER_UP	HNF1A RB1 TLX3 RUNX1 EP300 CDK6	1.15e-04	323	62	6	M9150
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DACH2 NFATC2 RUNX1 ME1 ADGRA3 ZFPM2	2.05e-07	182	62	6	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PKNOX2 DACH2 LAMA2 KIAA1755 ZFHX3 ZFPM2	2.26e-07	185	62	6	9f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 DACH2 KIAA1217 LAMA2 LMO4 ZFPM2	2.65e-07	190	62	6	1f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 DACH2 KIAA1217 LAMA2 LMO4 ZFPM2	2.65e-07	190	62	6	2306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	BPTF ARID1B HIVEP1 KDM6A SDK1 CDK6	2.81e-07	192	62	6	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	BPTF ARID1B HIVEP1 KDM6A SDK1 CDK6	2.90e-07	193	62	6	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 KIAA1217 LAMA2 GRIN2A ZFPM2	5.80e-06	184	62	5	c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	BPTF ARID1B MPHOSPH9 SDK1 CDK6	6.12e-06	186	62	5	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	BPTF ARID1B MPHOSPH9 SDK1 CDK6	6.12e-06	186	62	5	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PKNOX2 DACH2 LAMA2 ZFHX3 ZFPM2	6.28e-06	187	62	5	13731298bc562ec29582f5da1b4c97261284f6f1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 KIAA1217 LAMA2 GRIN2A ZFPM2	6.61e-06	189	62	5	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 KIAA1217 LAMA2 GRIN2A ZFPM2	6.61e-06	189	62	5	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 KIAA1217 LAMA2 GRIN2A ZFPM2	6.96e-06	191	62	5	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DACH2 KIAA1217 LAMA2 GRIN2A ZFPM2	6.96e-06	191	62	5	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 KIAA1217 LAMA2 GRIN2A ZFPM2	6.96e-06	191	62	5	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 KIAA1217 LAMA2 GRIN2A ZFPM2	7.14e-06	192	62	5	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 KIAA1217 LAMA2 GRIN2A ZFPM2	7.14e-06	192	62	5	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PKNOX2 LAMA2 LMO4 SDK1 ZFPM2	7.50e-06	194	62	5	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 KIAA1217 LAMA2 GRIN2A ZFPM2	7.50e-06	194	62	5	81713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCell	356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	NFATC2 RB1 ME1 CACNA2D3 CDK6	7.50e-06	194	62	5	11ff53a748160570d2908ea9eb9779c038e5b676
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 KIAA1217 LAMA2 GRIN2A ZFPM2	7.50e-06	194	62	5	ba7f971fb9a19423602da60770f23d9fead4a451
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 KIAA1217 LAMA2 GRIN2A ZFPM2	7.50e-06	194	62	5	cf0244a29934e515446ac917d3c30672b460fb04
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 KIAA1217 LAMA2 GRIN2A ZFPM2	7.50e-06	194	62	5	627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DACH2 KIAA1217 LAMA2 LMO4 ZFPM2	7.69e-06	195	62	5	803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell	367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	AP1B1 NFATC2 RB1 ME1 CDK6	7.69e-06	195	62	5	4008fa86b5166087a4b20f89ae07e1dfc87c855d
ToppCell	(3)_MNP-(3)_Macrophage_MARCOneg\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	AP1B1 NFATC2 RB1 ME1 CDK6	7.69e-06	195	62	5	e4b5e4b8832669fb4d1661ecd828b81e621d35c4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DACH2 KIAA1217 LAMA2 LMO4 ZFPM2	7.69e-06	195	62	5	4f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DACH2 KIAA1217 LAMA2 GRIN2A ZFPM2	7.89e-06	196	62	5	2b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCell	367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	NFATC2 RB1 ME1 CACNA2D3 CDK6	7.89e-06	196	62	5	e8c4eeb4b6c6d9bccca2adb942d4cfbaab39636c
ToppCell	Parenchymal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	LARP6 LAMA2 KIAA1755 MPHOSPH9	4.99e-05	145	62	4	e808502fa52baf1c400f3c9b918a167127e78af9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 LAMA2 GRIN2A ZFPM2	4.99e-05	145	62	4	051d964ff6bdc12ba3f0459d3e6ab16fa9507b0b
ToppCell	Adult-Mesenchymal-chondrocyte-D122\|Adult / Lineage, Cell type, age group and donor	FASN LAMA2 CACNA2D3 TMEM81	5.41e-05	148	62	4	81a1e6fdd942a612bf523c59b8b4974f6ca1fdce
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 LAMA2 SYN1 KIAA1755	5.70e-05	150	62	4	7a9d6a7ff8000e9a061e1b586e4c258cc91a2a09
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 LAMA2 SYN1 KIAA1755	5.70e-05	150	62	4	e5b843cb2bc847f6cab4cbec0a2a6a72fac50fee
ToppCell	P03-Epithelial-epithelial_progenitor_cell-epi_progenitor\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FASN ATP8A1 PRR36 KIAA1755	5.85e-05	151	62	4	fce04bce66411c21cd5d4d41375f26f1f50f3348
ToppCell	BAL-Severe-cDC_4\|Severe / Compartment, Disease Groups and Clusters	NEURL1 ZFHX3 CC2D2B TMEM81	6.97e-05	158	62	4	73f66689ef59f71b14cb7141ca5951cc47fe57c1
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FASN ACLY CPN2 ME1	8.24e-05	165	62	4	d449a568664a81d9b5538e8f409301448a32ac37
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PKNOX2 KIAA1755 MPHOSPH9 ADGRA3	8.64e-05	167	62	4	55c3c68af269fcf40f2b080ae4489523609ad388
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 LAMA2 GRIN2A ZFPM2	9.04e-05	169	62	4	a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DACH2 LAMA2 GRIN2A ZFPM2	9.25e-05	170	62	4	fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DACH2 LAMA2 GRIN2A ZFPM2	9.25e-05	170	62	4	03044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 KIAA1755 SNUPN TMEM81	9.68e-05	172	62	4	de4961f4037c439d3e0ec706a257b0ec17f4d5be
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8A1 HDAC4 RUNX1 CDK6	9.90e-05	173	62	4	5d7c53c6d1cdd385e44b79b82faec901747d1736
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8A1 HDAC4 RUNX1 CDK6	1.01e-04	174	62	4	9eab43885496b8586f8ec5b4bcb1fd5b209218e5
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L5-6_FEZF2_ANKRD20A1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HIVEP1 NFATC2 KIAA1217 SDK1	1.01e-04	174	62	4	99eb5e1aee136c7039e23b68a43a0fa3d775859f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 NFATC2 LAMA2 ZFPM2	1.06e-04	176	62	4	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 NFATC2 LAMA2 ZFPM2	1.06e-04	176	62	4	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KIAA1217 ZFHX3 SDK1 ZFPM2	1.06e-04	176	62	4	e4b21fd6a5e0c5950f27c3e1868318e48330ae5e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIAA1217 LAMA2 GRIN2A ZFPM2	1.10e-04	178	62	4	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	TET2 ATP8A1 ZFPM2 CACNA2D3	1.13e-04	179	62	4	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	LPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NFE2L3 PTPN3 ATP8A1 CACNA2D3	1.18e-04	181	62	4	0513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PKNOX2 LAMA2 KIAA1755 ZFPM2	1.20e-04	182	62	4	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	DACH2 LAMA2 KIAA1755 ZFHX3	1.23e-04	183	62	4	e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCell	TCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell-4\|TCGA-Uvea / Sample_Type by Project: Shred V9	SPRY3 NFATC2 LRRTM2 ME1	1.25e-04	184	62	4	9c56753e5e668be888662e4713cf4ce44e6c58fb
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP8A1 KIAA1217 ME1 CACNA2D3	1.25e-04	184	62	4	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NFE2L3 PTPN3 ATP8A1 CACNA2D3	1.25e-04	184	62	4	d0c212a8fbaad24597a84018442b25c61c17ea58
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 LAMA2 GRIN2A ZFPM2	1.25e-04	184	62	4	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP1 NFATC2 KDM6A SDK1	1.25e-04	184	62	4	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	PND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FASN ATP8A1 ACLY ME1	1.28e-04	185	62	4	fd51fef8c69e34c72017d8371ab0a0d7be5701f2
ToppCell	PND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FASN ATP8A1 ACLY ME1	1.28e-04	185	62	4	bea26e369ae91006052b973cd89b4c49afa9e553
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PKNOX2 LAMA2 KIAA1755 ZFPM2	1.28e-04	185	62	4	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	LAMA2 KIAA1755 SDK1 ZFPM2	1.28e-04	185	62	4	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA2 LMO4 ZFPM2 CACNA2D3	1.31e-04	186	62	4	bdbe290f81106a53c8c30a92fbb385597c62b2ac
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DACH2 RUNX1 ADGRA3 ZFPM2	1.34e-04	187	62	4	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	PKNOX2 LAMA2 SDK1 ZFPM2	1.34e-04	187	62	4	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	DACH2 LAMA2 ADGRA3 ZFPM2	1.39e-04	189	62	4	44e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell	(3)_Chondrocytes-(31)_Chondro-hyper\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	FASN NFATC2 ME1 CDK6	1.39e-04	189	62	4	394b153393904c3dba51a6bfe338afd554e66649
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NFATC2 LAMA2 GRIN2A ZFPM2	1.42e-04	190	62	4	1121eb607a984c59fbffe7220837fc178745aa55
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NFATC2 LAMA2 GRIN2A ZFPM2	1.42e-04	190	62	4	048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	PKNOX2 LAMA2 SDK1 ZFPM2	1.42e-04	190	62	4	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PKNOX2 LAMA2 SDK1 ZFPM2	1.45e-04	191	62	4	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DACH2 KIAA1217 LAMA2 LMO4	1.48e-04	192	62	4	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PKNOX2 LAMA2 SDK1 ZFPM2	1.48e-04	192	62	4	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIAA1217 LAMA2 GRIN2A ZFPM2	1.48e-04	192	62	4	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FASN ATP8A1 ACLY ME1	1.48e-04	192	62	4	7ccdb977320d09f21e70e7718ead73eeb56d0c48
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FASN ATP8A1 ACLY ME1	1.48e-04	192	62	4	f206c015f091234e2c86dfa66926e97b2ea99690
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DACH2 KIAA1217 LAMA2 LMO4	1.48e-04	192	62	4	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	PND28-Epithelial-Epithelial_Alveolar\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FASN ATP8A1 ACLY ME1	1.48e-04	192	62	4	69963e8dc6d6368243e61da133484eb23225625a
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FASN ATP8A1 ACLY ME1	1.48e-04	192	62	4	bfc68af68fdb99ddfe4add49671e4b4c26e6f962
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIAA1217 LAMA2 GRIN2A ZFPM2	1.48e-04	192	62	4	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	LA-14._Fibroblast_III\|LA / Chamber and Cluster_Paper	ARID1B LAMA2 ZFHX3 RUNX1	1.51e-04	193	62	4	7426c291bac59e539c427bcaae18abc7d397d44e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DACH2 LAMA2 GRIN2A ZFPM2	1.51e-04	193	62	4	f1199518c3626fd29bfce65070dd21a660671213
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BPTF ZBTB38 ATP8A1 MPHOSPH9	1.51e-04	193	62	4	544de0988510cc57744710d7cafe07aa27a0b99d
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA2 KIAA1755 SDK1 ZFPM2	1.51e-04	193	62	4	261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PKNOX2 LAMA2 LMO4 SDK1	1.54e-04	194	62	4	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 DACH2 KIAA1217 LAMA2	1.54e-04	194	62	4	90efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIAA1217 LAMA2 GRIN2A ZFPM2	1.54e-04	194	62	4	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PKNOX2 DACH2 KIAA1217 LAMA2	1.54e-04	194	62	4	df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell	LA-14._Fibroblast_III\|World / Chamber and Cluster_Paper	ARID1B ZFHX3 RUNX1 SDK1	1.54e-04	194	62	4	803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCell	367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|367C / Donor, Lineage, Cell class and subclass (all cells)	AP1B1 RB1 RUNX1 ME1	1.54e-04	194	62	4	e3688f4252aae5f849f025d7f453ff4c0c14590b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN3 SDK1 ADGRA3 CACNA2D3	1.57e-04	195	62	4	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	RA-02._Fibroblast_II\|RA / Chamber and Cluster_Paper	ARID1B LAMA2 ZFHX3 ZFPM2	1.57e-04	195	62	4	6a02ebbeb3199447ddce64d92d8809436e040eba
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZBTB38 ATP8A1 NFATC2 KIF19	1.57e-04	195	62	4	14a6466524c22920daa622fbc710daf1defb46c3
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	PKNOX2 LAMA2 SDK1 CACNA2D3	1.57e-04	195	62	4	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PKNOX2 LAMA2 SDK1 ZFPM2	1.60e-04	196	62	4	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	normal_Lung-Myeloid_cells-mo-Mac\|normal_Lung / Location, Cell class and cell subclass	AP1B1 RB1 ZFHX3 ME1	1.60e-04	196	62	4	4d3a3264b3d781139899448cde3b7a4f214ca14d
ToppCell	CV-Moderate-6\|CV / Virus stimulation, Condition and Cluster	BPTF NFATC2 LMO4 CDK6	1.60e-04	196	62	4	7bced0cc2112697593c478fa291b8ed3941fb811
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PKNOX2 LAMA2 SDK1 ZFPM2	1.60e-04	196	62	4	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NFATC2 LAMA2 KIAA1755 ZFPM2	1.63e-04	197	62	4	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DACH2 LAMA2 GRIN2A ZFPM2	1.63e-04	197	62	4	80e153790cef37b743e22a7370ff5b3a6abf147d
Drug	MDM2 inhibitor	PTPN3 KAT5 RB1 EP300	2.29e-06	35	61	4	CID010022508
Drug	1-acetyl-3-methyl-piperidine	MCPH1 RB1 LAMA2	2.97e-06	11	61	3	CID000107304
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	BPTF ZBTB38 HIVEP1 ZFHX3 RUNX1 EP300	7.90e-06	177	61	6	6434_DN
Drug	Alfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; HL60; HG-U133A	HDAC4 RB1 ACLY MARF1 KDM6A KRIT1	1.41e-05	196	61	6	1586_UP
Drug	Thioproperazine dimesylate [2347-80-0]; Up 200; 6.2uM; HL60; HG-U133A	RB1 NEURL1 MPHOSPH9 RUNX1 EP300 KRIT1	1.54e-05	199	61	6	1390_UP
Drug	Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A	MCPH1 RB1 NEURL1 CPN2 RUNX1 CDK6	1.58e-05	200	61	6	6839_UP
Drug	ginsenoside Rc	PTPN3 RB1 GRIN2A	2.02e-05	20	61	3	CID000100018
Drug	mimosine	PTPN3 RB1 SNUPN RUNX1 CDK6	2.14e-05	125	61	5	CID000003862
Disease	Bladder Neoplasm	BPTF HDAC4 RB1 LAMA2 KDM6A EP300	4.15e-07	140	60	6	C0005695
Disease	Malignant neoplasm of urinary bladder	BPTF HDAC4 RB1 LAMA2 KDM6A EP300	4.33e-07	141	60	6	C0005684
Disease	body weight	TET2 BPTF HNF1A FASN ZBTB38 HIVEP1 DACH2 NFATC2 KIAA1217 GON4L ZFHX3 SNUPN CDK6	1.18e-06	1261	60	13	EFO_0004338
Disease	protein-glutamine gamma-glutamyltransferase e measurement	NFE2L3 PTPN3 HNF1A CDK6	6.92e-06	60	60	4	EFO_0020690
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	RB1 RUNX1 EP300 CDK6	7.39e-06	61	60	4	C1961102
Disease	lung non-small cell carcinoma (is_implicated_in)	TET2 ARID1B ZFHX3 KDM6A CDK6	9.57e-06	139	60	5	DOID:3908 (is_implicated_in)
Disease	birth weight	TET2 HNF1A MCPH1 RB1 ME1 ZFPM2 CDK6	1.63e-05	399	60	7	EFO_0004344
Disease	Leukemia, Myelocytic, Acute	TET2 RUNX1 EP300 SLX4 CDK6	2.75e-05	173	60	5	C0023467
Disease	Breast Cancer, Familial	MCPH1 SLX4 RAD54L	3.12e-05	30	60	3	C0346153
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	TET2 BPTF ARID1B HIVEP1 LAMA2 ZFHX3 GRIN2A SDK1 CACNA2D3	3.28e-05	801	60	9	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	Squamous cell carcinoma of esophagus	FASN RB1 KDM6A EP300	4.28e-05	95	60	4	C0279626
Disease	testosterone measurement	PKNOX2 TET2 NCOA6 HNF1A FASN ARID1B KAT5 ZFHX3 SNUPN ZFPM2 CDK6	4.59e-05	1275	60	11	EFO_0004908
Disease	diet measurement	NCOA6 ARID1B ZBTB38 KIAA1217 LAMA2 ZFHX3 RUNX1 ME1 SDK1 ZFPM2	4.63e-05	1049	60	10	EFO_0008111
Disease	attention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia	HDAC4 NEURL1 GRIN2A ZFPM2	5.44e-05	101	60	4	EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
Disease	pulmonary function measurement, forced expiratory volume	TET2 ZBTB38 HDAC4	5.91e-05	37	60	3	EFO_0003892, EFO_0004314
Disease	liposarcoma	FASN CDK6	6.07e-05	6	60	2	C0023827
Disease	Leukemia, Myelomonocytic, Chronic	TET2 KDM6A	6.07e-05	6	60	2	C0023480
Disease	Obesity	FASN ACLY ZFHX3 ME1 EP300	6.17e-05	205	60	5	C0028754
Disease	sexual dimorphism measurement	TET2 BPTF NCOA6 HNF1A ZBTB38 KAT5 ZNF592 ZFHX3 GRIN2A CDK6	7.21e-05	1106	60	10	EFO_0021796
Disease	Liver carcinoma	HNF1A FASN ARID1B RB1 ACLY ME1 RAD54L	7.46e-05	507	60	7	C2239176
Disease	Neoplasm of uncertain or unknown behavior of breast	ARID1B RB1 EP300	8.06e-05	41	60	3	C0496956
Disease	Breast adenocarcinoma	ARID1B RB1 EP300	8.06e-05	41	60	3	C0858252
Disease	esophagus squamous cell carcinoma (is_implicated_in)	TET2 RUNX1 KDM6A	1.07e-04	45	60	3	DOID:3748 (is_implicated_in)
Disease	colorectal cancer (is_implicated_in)	HNF1A GRIN2A KDM6A EP300	1.10e-04	121	60	4	DOID:9256 (is_implicated_in)
Disease	basophil count, eosinophil count	BPTF NFATC2 RUNX1 LMO4 CDK6	1.32e-04	241	60	5	EFO_0004842, EFO_0005090
Disease	synaptotagmin-11 measurement	GON4L ZFPM2	1.45e-04	9	60	2	EFO_0802108
Disease	L2 Acute Lymphoblastic Leukemia	RB1 RUNX1 CDK6	1.46e-04	50	60	3	C0023453
Disease	neuroticism measurement, cognitive function measurement	TET2 HIVEP1 KIAA1217 ZFHX3 MPHOSPH9 GRIN2A USP33	1.48e-04	566	60	7	EFO_0007660, EFO_0008354
Disease	risk-taking behaviour	TET2 BPTF ARID1B HIVEP1 ZFHX3 GRIN2A SDK1 EP300	1.52e-04	764	60	8	EFO_0008579
Disease	Childhood Acute Lymphoblastic Leukemia	RB1 RUNX1 CDK6	1.65e-04	52	60	3	C0023452
Disease	brain-derived neurotrophic factor measurement	RUNX1 ZFPM2	2.21e-04	11	60	2	EFO_0011018
Disease	metabolite measurement, body weight gain	KIF19 ZFHX3	2.65e-04	12	60	2	EFO_0004566, EFO_0004725
Disease	tumor necrosis factor receptor superfamily member EDAR measurement	RUNX1 ZFPM2	2.65e-04	12	60	2	EFO_0008310
Disease	calcium measurement	TET2 NCOA6 ARID1B HDAC4 ZFHX3 ZFPM2 CDK6	2.78e-04	628	60	7	EFO_0004838
Disease	colorectal cancer (is_marker_for)	TET2 HNF1A FASN ZFHX3	2.98e-04	157	60	4	DOID:9256 (is_marker_for)
Disease	total blood protein measurement	PTPN3 ZBTB38 MCPH1 RUNX1 CDK6 CC2D2B	3.00e-04	449	60	6	EFO_0004536
Disease	Malignant neoplasm of breast	NCOA6 FASN ARID1B HDAC4 RB1 LAMA2 TRAPPC8 EP300 RAD54L	3.02e-04	1074	60	9	C0006142
Disease	osteoarthritis, knee	KIAA1217 MPHOSPH9 SNUPN EP300	3.06e-04	158	60	4	EFO_0004616
Disease	alcohol and nicotine codependence	PKNOX2 HIVEP1	3.13e-04	13	60	2	EFO_0004776
Disease	MYELODYSPLASTIC SYNDROME	TET2 RUNX1 SLX4	3.49e-04	67	60	3	C3463824
Disease	red blood cell density measurement	TET2 PTPN3 HNF1A ARID1B HIVEP1 RUNX1 ZFPM2 CDK6	3.93e-04	880	60	8	EFO_0007978
Disease	Neoplasm of uncertain or unknown behavior of bladder	RB1 KDM6A	4.20e-04	15	60	2	C0496930
Disease	Benign neoplasm of bladder	RB1 KDM6A	4.20e-04	15	60	2	C0154017
Disease	Carcinoma in situ of bladder	RB1 KDM6A	4.20e-04	15	60	2	C0154091
Disease	Autosomal recessive primary microcephaly	MCPH1 CDK6	4.20e-04	15	60	2	cv:C3711387
Disease	response to olanzapine	HIVEP1 ZFPM2	4.20e-04	15	60	2	GO_0097333
Disease	wellbeing measurement	BPTF FASN HIVEP1 ZFHX3 GRIN2A SDK1 CACNA2D3	4.97e-04	692	60	7	EFO_0007869
Disease	hepatocellular carcinoma (is_implicated_in)	TET2 HNF1A ZFHX3 KDM6A	5.11e-04	181	60	4	DOID:684 (is_implicated_in)
Disease	peak expiratory flow	TET2 ZBTB38 HDAC4 RUNX1 CACNA2D3 CDK6	5.19e-04	498	60	6	EFO_0009718
Disease	autosomal dominant compelling helio-ophthalmic outburst syndrome	PKNOX2 KIAA1755 ZFHX3	5.25e-04	77	60	3	EFO_0007887
Disease	schizophrenia, irritable bowel syndrome	MPHOSPH9 EP300	5.42e-04	17	60	2	EFO_0000555, MONDO_0005090
Disease	breast cancer (is_marker_for)	TET2 KAT5 ZFHX3 KDM6A	5.55e-04	185	60	4	DOID:1612 (is_marker_for)
Disease	heart failure	BPTF ZNF592 ZFHX3 CDK6	5.55e-04	185	60	4	EFO_0003144
Disease	Hypermetropia, Myopia	BPTF ZBTB38 LAMA2 CACNA2D3	6.01e-04	189	60	4	HP_0000540, HP_0000545
Disease	Carcinoma of bladder	RB1 KDM6A	6.09e-04	18	60	2	C0699885
Disease	smoking status measurement, chronic obstructive pulmonary disease	TET2 ZBTB38 HDAC4	7.76e-04	88	60	3	EFO_0000341, EFO_0006527
Disease	creatinine measurement	TET2 PTPN3 HNF1A ZNF592 LAMA2 KIAA1755 ZFHX3 SNUPN	8.80e-04	995	60	8	EFO_0004518
Disease	Autosomal Recessive Primary Microcephaly	MCPH1 CDK6	9.15e-04	22	60	2	C3711387
Disease	executive function measurement	TET2 ZBTB38 TLX3 GRIN2A SDK1	1.01e-03	376	60	5	EFO_0009332
Disease	Neoplasm of the genitourinary tract	RB1 ZFHX3	1.09e-03	24	60	2	cv:C0042065
Disease	phospholipids:total lipids ratio	NFE2L3 BPTF HNF1A KAT5	1.19e-03	227	60	4	EFO_0020946
Disease	Sezary Syndrome	TET2 RB1	1.38e-03	27	60	2	C0036920
Disease	alopecia	TET2 ZBTB38 HDAC4 RUNX1	1.48e-03	241	60	4	MONDO_0004907
Disease	neutrophil percentage of leukocytes	TET2 HNF1A CRTC3 ZBTB38 HIVEP1 CDK6	1.48e-03	610	60	6	EFO_0007990
Disease	stimulant use measurement	HIVEP1 RB1	1.49e-03	28	60	2	EFO_0600076
Disease	cortical surface area measurement	TET2 ARID1B MCPH1 TLX3 LAMA2 KIAA1755 ZFHX3 MPHOSPH9 CDK6	1.50e-03	1345	60	9	EFO_0010736
Disease	cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement	NFE2L3 BPTF HNF1A KAT5	1.52e-03	243	60	4	EFO_0004612, EFO_0020944
Disease	amyotrophic lateral sclerosis (is_marker_for)	BPTF HDAC4	1.59e-03	29	60	2	DOID:332 (is_marker_for)
Disease	Drug-Induced Stevens Johnson Syndrome	RB1 EP300	1.59e-03	29	60	2	C1274933
Disease	Mycoplasma-Induced Stevens-Johnson Syndrome	RB1 EP300	1.59e-03	29	60	2	C3658301
Disease	Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum	RB1 EP300	1.59e-03	29	60	2	C3658302
Disease	Toxic Epidermal Necrolysis	RB1 EP300	1.59e-03	29	60	2	C0014518
Disease	Hematopoetic Myelodysplasia	TET2 RUNX1	1.59e-03	29	60	2	C2713368
Disease	cardiac arrhythmia	NEURL1 ZFHX3	1.71e-03	30	60	2	EFO_0004269
Disease	Stevens-Johnson Syndrome	RB1 EP300	1.71e-03	30	60	2	C0038325
Disease	myelodysplastic syndrome (is_implicated_in)	TET2 ZFPM2	1.71e-03	30	60	2	DOID:0050908 (is_implicated_in)
Disease	pulse pressure measurement	TET2 FASN ARID1B NFATC2 KIAA1217 KIAA1755 ZFHX3 ZFPM2 CDK6	1.90e-03	1392	60	9	EFO_0005763
Disease	asthma, Eczema, allergic rhinitis	ZBTB38 NFATC2 RUNX1	1.94e-03	121	60	3	EFO_0005854, HP_0000964, MONDO_0004979
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	NFE2L3 HNF1A KAT5	1.94e-03	121	60	3	EFO_0008595, EFO_0020943

Protein segments in the cluster

Peptide	Gene	Start	Entry
SPHLQGQQIPNSLSN	EP300	2291	Q09472
SNNLTALHPALFQNL	CPN2	346	P22792
HANSLPLNSTPQLDN	ADGRA3	1126	Q8IWK6
PLNSTPQLDNSLTEH	ADGRA3	1131	Q8IWK6
QNQHPSGATPTLNQL	ARID1B	491	Q8NFD5
DSHLPPSQNTSELNT	CDK6	311	Q00534
HPSSNLLDLNPQSIN	AP1B1	191	Q10567
TQLENNIPSSFLHPN	BPTF	911	Q12830
PPQQLLDIFLHNSNA	CC2D2B	1126	Q6DHV5
APTLNPLQQNHLLTN	DACH2	296	Q96NX9
SSLLENLQNNHPTAP	ATP8A1	461	Q9Y2Q0
LESACPLNLPLQNNH	RB1	586	P06400
SQLTNQPPCLDSSQH	RAD54L	56	Q92698
QNRSPHQESLSENNP	PTPN3	431	P26045
QGQSSALLHPSPTNQ	NFATC2	791	Q13469
QNLDLSFNQLSSLHP	LRRTM2	136	O43300
QSAPLPQNAQALQHL	HDAC4	466	P56524
QQLNIHGLLPPSFNS	ME1	36	P48163
SHDNPSNSLCEAPLN	MCPH1	201	Q8NEM0
INGHLNSLQSNPLLP	LMO4	146	P61968
LSSPQELHQASSPDN	KIAA1755	211	Q5JYT7
ASNNSLSGQPLQHPL	KIAA2026	1946	Q5HYC2
NLKQPSPNGNLFSSH	ZFPM2	921	Q8WW38
DQPLSSSSCLQPNHR	KAT5	131	Q92993
IQNQNGHPTLPSNSV	KDM6A	676	O15550
PFLQLNSHTTNPEQT	NFE2L3	341	Q9Y4A8
QLPERNLTSASNPNH	MPHOSPH9	271	Q99550
LHSLEQTSPGLNQQP	HNF1A	386	P20823
LSPSGHQNLFLSPNA	LARP6	361	Q9BRS8
CNPNLLNGQLSSPLH	KRIT1	346	O00522
LNIPSNNFSPTCHLD	LAMA2	811	P24043
LSSDAQHLQNSALPP	KIF19	686	Q2TAC6
QHLQNSALPPLSTES	KIF19	691	Q2TAC6
KEPSNSLNLPHSNEL	NCOA6	1541	Q14686
PNDHFNNLPVNISLS	CACNA2D3	156	Q8IZS8
LNNHPQTSVPNASAL	CRTC3	346	Q6UUV7
NLQQPEDSQSPHLAS	CRYBG2	1191	Q8N1P7
HLLATCNPNLNPEAT	GON4L	706	Q3T8J9
NLNSPDELQSSHPSA	CFAP126	151	Q5VTH2
NPLNANPGLTHTSNS	MS4A18	116	Q3C1V0
SSLSLSPANHENQPS	MARF1	1566	Q9Y4F3
LQAQQSPAPTHNSLF	FASN	2321	P49327
PQNLLVSPNSSHSHA	SDK1	671	Q7Z5N4
INLHSQDLLQNSPNS	PKNOX2	191	Q96KN3
NPRASLNHSTAFNPQ	RUNX1	221	Q01196
PHPQLNKSQSLTNAF	SYN1	656	P17600
SPQAPNALAVHLLQA	PRR36	871	Q9H6K5
PSQHSVALLNPAQNL	KIAA1217	896	Q5T5P2
QDLNSTAAPHPRLSQ	SNUPN	16	O95149
LSQCHQLQPLPQHLS	SPRY3	66	O43610
QLQPLPQHLSQSSIA	SPRY3	71	O43610
SSQPLLQAPHCQTLA	SLX4	1616	Q8IY92
NQPPTAAHTANFLLN	ACLY	426	P53396
QSQPNLHSNSLENPT	USP42	536	Q9H9J4
CPIPQNSLNSQHSRA	NEURL1	271	O76050
NSLNSQHSRALPAQL	NEURL1	276	O76050
QPQASQDQDSHTLSP	ZNF592	1251	Q92610
SLNDSIQPDPLCLHN	TLX3	251	O43711
LPPNLVNLNFHQSLT	TMEM81	181	Q6P7N7
RAHPLQLEQSSDPSN	TRAPPC8	296	Q9Y2L5
HLPSNFLAQPVNDSA	ZBTB49	271	Q6ZSB9
QNPHSSELPTLNFQD	ZBTB38	606	Q8NAP3
QAAQTQPSQSSHLPQ	TET2	726	Q6N021
TQDLPNQPICQTNHS	HIVEP1	1661	P15822
HSNDLSTPQILPSNE	USP33	416	Q8TEY7
AQSHSALLQPSQHPE	ZFHX3	1861	Q15911
QGQHPLTLNESNPNT	GRIN2A	981	Q12879