Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransporter activity

CACNA1E GJA3 ANO2 ABCA2 SLC9A2 PIEZO2 TRPC7 MFSD14B XKR9 SLC16A3 SLC45A3 ABCA12 SLC15A4 PIEZO1 SLC6A15 CACNA1H CACNA1G ATP2B1 ATP2B4 ANO3 KCNH4 SLC35A5 SLC35B1

3.33e-1112897023GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1E GJA3 ANO2 ABCA2 SLC9A2 PIEZO2 TRPC7 MFSD14B SLC16A3 SLC45A3 ABCA12 SLC15A4 PIEZO1 SLC6A15 CACNA1H CACNA1G ATP2B1 ATP2B4 ANO3 KCNH4 SLC35A5 SLC35B1

4.35e-1111807022GO:0022857
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1E ANO2 SLC9A2 PIEZO2 TRPC7 SLC16A3 SLC45A3 SLC15A4 PIEZO1 SLC6A15 CACNA1H CACNA1G ATP2B1 ATP2B4 ANO3 KCNH4

1.10e-087937016GO:0015075
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1E SLC9A2 PIEZO2 TRPC7 SLC16A3 SLC45A3 SLC15A4 PIEZO1 SLC6A15 CACNA1H CACNA1G ATP2B1 ATP2B4 KCNH4

6.10e-086647014GO:0008324
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA1E ANO2 SLC9A2 TRPC7 SLC16A3 SLC45A3 SLC15A4 SLC6A15 CACNA1H CACNA1G ATP2B1 ATP2B4 ANO3 KCNH4

3.08e-077587014GO:0015318
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCA2 SLC9A2 SLC16A3 SLC45A3 ABCA12 SLC15A4 SLC6A15 ATP2B1 ATP2B4 SLC35A5 SLC35B1

7.82e-074777011GO:0022804
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ANO2 ABCA2 XKR9 ABCA12 ANO3

9.49e-0751705GO:0140303
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA1E SLC9A2 TRPC7 SLC16A3 SLC45A3 SLC15A4 SLC6A15 CACNA1H CACNA1G ATP2B1 ATP2B4 KCNH4

1.67e-066277012GO:0022890
GeneOntologyMolecularFunctionchannel activity

CACNA1E GJA3 ANO2 PIEZO2 TRPC7 PIEZO1 CACNA1H CACNA1G ANO3 KCNH4

1.40e-055257010GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1E GJA3 ANO2 PIEZO2 TRPC7 PIEZO1 CACNA1H CACNA1G ANO3 KCNH4

1.42e-055267010GO:0022803
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1E CACNA1H CACNA1G

1.46e-0514703GO:0008331
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1E TRPC7 CACNA1H CACNA1G ATP2B1 ATP2B4

1.49e-05151706GO:0015085
GeneOntologyMolecularFunctiongated channel activity

CACNA1E ANO2 PIEZO2 PIEZO1 CACNA1H CACNA1G ANO3 KCNH4

2.16e-05334708GO:0022836
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1E ANO2 PIEZO2 TRPC7 PIEZO1 CACNA1H CACNA1G ANO3 KCNH4

3.11e-05459709GO:0005216
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1E SLC9A2 TRPC7 SLC6A15 CACNA1H CACNA1G ATP2B1 ATP2B4 KCNH4

3.44e-05465709GO:0046873
GeneOntologyMolecularFunctionlow voltage-gated calcium channel activity

CACNA1H CACNA1G

3.63e-053702GO:0008332
GeneOntologyMolecularFunctionphospholipid scramblase activity

ANO2 XKR9 ANO3

6.95e-0523703GO:0017128
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC9A2 SLC16A3 SLC45A3 SLC15A4 SLC6A15 SLC35A5 SLC35B1

7.90e-05296707GO:0015291
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC9A2 SLC16A3 SLC45A3 SLC15A4 SLC6A15 ATP2B1 ATP2B4

8.78e-05301707GO:0022853
GeneOntologyMolecularFunctionsolute:proton symporter activity

SLC16A3 SLC45A3 SLC15A4

8.98e-0525703GO:0015295
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1E PIEZO2 TRPC7 PIEZO1 CACNA1H CACNA1G KCNH4

1.97e-04343707GO:0005261
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1E CACNA1H CACNA1G

5.62e-0446703GO:0005245
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA2 ABCA12 ATP2B1 ATP2B4

5.84e-04109704GO:0042626
GeneOntologyMolecularFunctionlipid transporter activity

ANO2 ABCA2 XKR9 ABCA12 ANO3

6.25e-04196705GO:0005319
GeneOntologyMolecularFunctionpyrimidine nucleotide-sugar transmembrane transporter activity

SLC35A5 SLC35B1

6.53e-0411702GO:0015165
GeneOntologyMolecularFunctionP-type calcium transporter activity

ATP2B1 ATP2B4

6.53e-0411702GO:0005388
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC16A3 SLC45A3 SLC15A4 SLC6A15

8.12e-04119704GO:0015294
GeneOntologyMolecularFunctionnucleotide-sugar transmembrane transporter activity

SLC35A5 SLC35B1

1.07e-0314702GO:0005338
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1E TRPC7 CACNA1H CACNA1G

1.10e-03129704GO:0005262
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

SLC15A4 SLC35A5 SLC35B1

1.17e-0359703GO:1901505
GeneOntologyMolecularFunctionmechanosensitive monoatomic ion channel activity

PIEZO2 PIEZO1

1.79e-0318702GO:0008381
GeneOntologyMolecularFunctionsymporter activity

SLC16A3 SLC45A3 SLC15A4 SLC6A15

1.91e-03150704GO:0015293
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1E CACNA1H CACNA1G KCNH4

2.00e-03152704GO:0022843
GeneOntologyMolecularFunctionintracellularly calcium-gated channel activity

ANO2 ANO3

2.21e-0320702GO:0141147
GeneOntologyMolecularFunctionintracellularly calcium-gated chloride channel activity

ANO2 ANO3

2.21e-0320702GO:0005229
GeneOntologyMolecularFunctionphospholipid transporter activity

ANO2 XKR9 ANO3

2.24e-0374703GO:0005548
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC9A2 SLC6A15 CACNA1H CACNA1G

3.07e-03171704GO:0015081
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCA2 ABCA12 ATP2B1 ATP2B4

3.54e-03178704GO:0015399
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

CACNA1H CACNA1G

3.73e-0326702GO:0005248
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1E CACNA1H CACNA1G KCNH4

3.83e-03182704GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1E CACNA1H CACNA1G KCNH4

3.99e-03184704GO:0022832
GeneOntologyMolecularFunctionscaffold protein binding

CACNA1H CACNA1G ATP2B4

4.27e-0393703GO:0097110
GeneOntologyMolecularFunctionproton transmembrane transporter activity

SLC9A2 SLC16A3 SLC45A3 SLC15A4

4.30e-03188704GO:0015078
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA2 ABCA12

4.32e-0328702GO:0140326
GeneOntologyMolecularFunctionATP-dependent activity

ABCA2 ABCA12 ZGRF1 SRPRA ACSM2A ATP2B1 ATP2B4

5.64e-03614707GO:0140657
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP2B1 ATP2B4

7.07e-0336702GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP2B1 ATP2B4

7.07e-0336702GO:0015662
GeneOntologyBiologicalProcessnegative regulation of synaptic vesicle exocytosis

RAP1A RAP1B FMR1

7.43e-076703GO:2000301
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

CACNA1E ANO2 SLC9A2 PIEZO2 TRPC7 FMR1 SLC15A4 PIEZO1 SLC6A15 CACNA1H CACNA1G ATP2B1 ATP2B4 ANO3 KCNH4

3.91e-0611157015GO:0034220
GeneOntologyBiologicalProcessregulation of intracellular lipid transport

LDLRAP1 ABCA2 ABCA12

1.04e-0513703GO:0032377
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

CACNA1E SLC9A2 PIEZO2 TRPC7 FMR1 SLC15A4 PIEZO1 SLC6A15 CACNA1H CACNA1G ATP2B1 ATP2B4 KCNH4

1.46e-059427013GO:0098655
GeneOntologyBiologicalProcessregulation of regulated secretory pathway

CACNA1E RAP1A RAP1B FMR1 CACNA1H CACNA1G

2.05e-05165706GO:1903305
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

CACNA1E CACNA1H CACNA1G ATP2B4

2.11e-0548704GO:0098703
GeneOntologyBiologicalProcesscalcium ion import into cytosol

CACNA1E CACNA1H CACNA1G ATP2B4

2.11e-0548704GO:1902656
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

CACNA1E ANO2 SLC9A2 TRPC7 FMR1 SLC15A4 SLC6A15 CACNA1H CACNA1G ATP2B1 ATP2B4 ANO3 KCNH4

3.27e-0510177013GO:0098660
GeneOntologyBiologicalProcesstransmission of nerve impulse

OTOA CACNA1E FMR1 CACNA1H CACNA1G

3.94e-05112705GO:0019226
GeneOntologyBiologicalProcessmonoatomic ion transport

CACNA1E ANO2 SLC9A2 PIEZO2 TRPC7 FMR1 SLC15A4 PIEZO1 SLC6A15 CACNA1H CACNA1G ATP2B1 ATP2B4 ANO3 KCNH4

4.65e-0513747015GO:0006811
GeneOntologyBiologicalProcesslipid translocation

ABCA2 XKR9 ABCA12 ANO3

5.14e-0560704GO:0034204
GeneOntologyBiologicalProcessregulated exocytosis

CACNA1E RAP1A RAP1B FMR1 ABCA12 CACNA1H CACNA1G

5.81e-05291707GO:0045055
GeneOntologyBiologicalProcessregulation of synaptic vesicle exocytosis

CACNA1E RAP1A RAP1B FMR1

5.85e-0562704GO:2000300
GeneOntologyBiologicalProcesscalcium ion export

ATP2B1 ATP2B4

6.78e-054702GO:1901660
GeneOntologyBiologicalProcessregulation of membrane lipid distribution

ABCA2 XKR9 ABCA12 ANO3

7.04e-0565704GO:0097035
GeneOntologyBiologicalProcesspositive regulation of intracellular lipid transport

LDLRAP1 ABCA12

1.13e-045702GO:0032379
GeneOntologyBiologicalProcessmonoatomic cation transport

CACNA1E SLC9A2 PIEZO2 TRPC7 FMR1 SLC15A4 PIEZO1 SLC6A15 CACNA1H CACNA1G ATP2B1 ATP2B4 KCNH4

1.22e-0411577013GO:0006812
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

CACNA1E SLC9A2 CACNA1H CACNA1G ATP2B4

1.22e-04142705GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

CACNA1E SLC9A2 CACNA1H CACNA1G ATP2B4

1.22e-04142705GO:0098659
GeneOntologyBiologicalProcessimport across plasma membrane

CACNA1E SLC9A2 SLC15A4 CACNA1H CACNA1G ATP2B4

1.30e-04230706GO:0098739
GeneOntologyBiologicalProcessregulation of exocytosis

CACNA1E RAP1A RAP1B FMR1 CACNA1H CACNA1G

1.40e-04233706GO:0017157
GeneOntologyBiologicalProcessvascular associated smooth muscle contraction

ADRA2B CACNA1G ATP2B1

1.57e-0431703GO:0014829
GeneOntologyBiologicalProcessnegative regulation of regulated secretory pathway

RAP1A RAP1B FMR1

1.73e-0432703GO:1903306
GeneOntologyBiologicalProcessimport into cell

LDLRAP1 CACNA1E RAP1A ABCA2 SLC9A2 FMR1 XKR9 SLC15A4 DNER CACNA1H CACNA1G ATP2B4

2.42e-0410747012GO:0098657
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

CACNA1E SLC9A2 TRPC7 FMR1 SLC15A4 SLC6A15 CACNA1H CACNA1G ATP2B1 ATP2B4 KCNH4

2.59e-049227011GO:0098662
GeneOntologyBiologicalProcessregulation of receptor-mediated endocytosis involved in cholesterol transport

LDLRAP1 ABCA2

3.14e-048702GO:1905600
GeneOntologyBiologicalProcesscalcium ion import

CACNA1E CACNA1H CACNA1G ATP2B4

3.46e-0498704GO:0070509
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

CACNA1E TRPC7 FMR1 CACNA1H CACNA1G ATP2B1 ATP2B4

3.64e-04392707GO:0070588
GeneOntologyBiologicalProcessnegative regulation of exocytosis

RAP1A RAP1B FMR1

4.80e-0445703GO:0045920
GeneOntologyBiologicalProcessregulation of calcium ion-dependent exocytosis

RAP1B CACNA1H CACNA1G

4.80e-0445703GO:0017158
GeneOntologyBiologicalProcessresponse to endoplasmic reticulum stress

TMEM67 UBXN4 ERP27 RNF103 CTH GRINA

4.95e-04295706GO:0034976
GeneOntologyBiologicalProcessreceptor-mediated endocytosis involved in cholesterol transport

LDLRAP1 ABCA2

6.12e-0411702GO:0090118
GeneOntologyBiologicalProcessexocytosis

CACNA1E RAP1A RAP1B FMR1 ABCA12 CACNA1H CACNA1G

6.66e-04434707GO:0006887
GeneOntologyBiologicalProcessregulation of neurotransmitter secretion

CACNA1E RAP1A RAP1B FMR1

6.98e-04118704GO:0046928
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC9A2 SLC6A15 CACNA1H CACNA1G ATP2B4

7.07e-04208705GO:0035725
GeneOntologyBiologicalProcesspositive regulation of miRNA-mediated gene silencing

FMR1 PUM2

7.33e-0412702GO:2000637
GeneOntologyBiologicalProcesspyrimidine nucleotide-sugar transmembrane transport

SLC35A5 SLC35B1

7.33e-0412702GO:0090481
GeneOntologyBiologicalProcessregulation of vascular associated smooth muscle contraction

ADRA2B ATP2B1

7.33e-0412702GO:0003056
GeneOntologyBiologicalProcessregulation of intracellular sterol transport

LDLRAP1 ABCA2

7.33e-0412702GO:0032380
GeneOntologyBiologicalProcessregulation of intracellular cholesterol transport

LDLRAP1 ABCA2

7.33e-0412702GO:0032383
GeneOntologyBiologicalProcesspositive regulation of acrosome reaction

PRSS37 CACNA1H

7.33e-0412702GO:2000344
GeneOntologyBiologicalProcesslipid homeostasis

LDLRAP1 ABCA2 ABCA12 FUNDC2 ACSM2A

7.54e-04211705GO:0055088
GeneOntologyBiologicalProcessintracellular lipid transport

LDLRAP1 ABCA2 ABCA12

7.77e-0453703GO:0032365
GeneOntologyBiologicalProcessregulation of blood circulation

CACNA1E ADRA2B CACNA1H CACNA1G ATP2B1 ATP2B4

8.35e-04326706GO:1903522
GeneOntologyBiologicalProcesspositive regulation of post-transcriptional gene silencing by RNA

FMR1 PUM2

8.64e-0413702GO:1900370
GeneOntologyBiologicalProcesspositive regulation of post-transcriptional gene silencing

FMR1 PUM2

8.64e-0413702GO:0060148
GeneOntologyBiologicalProcessnucleotide-sugar transmembrane transport

SLC35A5 SLC35B1

8.64e-0413702GO:0015780
GeneOntologyBiologicalProcesssynaptic vesicle exocytosis

CACNA1E RAP1A RAP1B FMR1

8.65e-04125704GO:0016079
GeneOntologyBiologicalProcessRap protein signal transduction

RAP1A RAP1B

1.01e-0314702GO:0032486
GeneOntologyBiologicalProcesspositive regulation of integrin activation

RAP1B PIEZO1

1.01e-0314702GO:0033625
GeneOntologyBiologicalProcesssmooth muscle contraction

ADRA2B CACNA1G ATP2B1 ATP2B4

1.09e-03133704GO:0006939
GeneOntologyBiologicalProcessneuronal action potential

FMR1 CACNA1H CACNA1G

1.28e-0363703GO:0019228
GeneOntologyBiologicalProcessregulation of neurotransmitter transport

CACNA1E RAP1A RAP1B FMR1

1.35e-03141704GO:0051588
HumanPhenoUpper limb postural tremor

COL6A3 CACNA1G ANO3

1.68e-0511253HP:0007351
HumanPhenoLumbar hyperlordosis

COL6A3 COL12A1 PIEZO2 MED12 NSDHL

9.78e-0599255HP:0002938
HumanPhenoLong toe

COL6A3 COL12A1 PIEZO2 ATP2B1 MED12 NSDHL

1.24e-04168256HP:0010511
HumanPhenoReduced muscle collagen VI

COL6A3 COL12A1

1.38e-044252HP:0030095
HumanPhenoCurved toe phalanx

COL6A3 COL12A1

1.38e-044252HP:0010176
HumanPhenoReduced maximal expiratory pressure

COL6A3 COL12A1

1.38e-044252HP:0012497
HumanPhenoLimb tremor

COL6A3 CACNA1G ANO3

1.51e-0422253HP:0200085
DomainVDCCAlpha1

CACNA1E CACNA1H CACNA1G

5.68e-0610693IPR002077
DomainPIEZO

PIEZO2 PIEZO1

1.35e-052692PF15917
DomainPiezo_RRas-bd_dom

PIEZO2 PIEZO1

1.35e-052692IPR031334
DomainPiezo

PIEZO2 PIEZO1

1.35e-052692IPR027272
DomainATP2B1/4

ATP2B1 ATP2B4

1.35e-052692IPR030319
DomainPiezo_RRas_bdg

PIEZO2 PIEZO1

1.35e-052692PF12166
DomainPiezo_dom

PIEZO2 PIEZO1

1.35e-052692IPR031805
DomainVDCC_T_a1

CACNA1H CACNA1G

4.03e-053692IPR005445
DomainIon_trans_dom

CACNA1E TRPC7 CACNA1H CACNA1G KCNH4

6.39e-05114695IPR005821
DomainIon_trans

CACNA1E TRPC7 CACNA1H CACNA1G KCNH4

6.39e-05114695PF00520
DomainATP_Ca_trans_C

ATP2B1 ATP2B4

8.03e-054692IPR022141
DomainATP_Ca_trans_C

ATP2B1 ATP2B4

8.03e-054692PF12424
DomainP-type_ATPase_IIB

ATP2B1 ATP2B4

8.03e-054692IPR006408
DomainAnoct_dimer

ANO2 ANO3

2.79e-047692PF16178
DomainAnoct_dimer

ANO2 ANO3

2.79e-047692IPR032394
DomainAnoctamin

ANO2 ANO3

5.94e-0410692PF04547
DomainAnoctamin

ANO2 ANO3

5.94e-0410692IPR007632
DomainABC_A

ABCA2 ABCA12

8.67e-0412692IPR026082
DomainChannel_four-helix_dom

CACNA1E CACNA1H CACNA1G

1.22e-0357693IPR027359
Domain-

CACNA1E CACNA1H CACNA1G

1.22e-03576931.20.120.350
DomainMFS_dom

MFSD14B SLC16A3 SLC45A3 SLC15A4

1.53e-03134694IPR020846
Domain-

ATP2B1 ATP2B4

1.56e-03166921.20.1110.10
DomainATPase_P-typ_TM_dom

ATP2B1 ATP2B4

1.56e-0316692IPR023298
DomainATPase_P-typ_cation-transptr_C

ATP2B1 ATP2B4

1.76e-0317692IPR006068
DomainCation_ATPase_C

ATP2B1 ATP2B4

1.76e-0317692PF00689
DomainCation_ATPase_N

ATP2B1 ATP2B4

1.98e-0318692PF00690
DomainCation_ATPase_N

ATP2B1 ATP2B4

1.98e-0318692SM00831
DomainATPase_P-typ_cation-transptr_N

ATP2B1 ATP2B4

2.21e-0319692IPR004014
DomainMFS_1

MFSD14B SLC16A3 SLC45A3

2.90e-0377693PF07690
DomainMFS

MFSD14B SLC16A3 SLC45A3

2.90e-0377693IPR011701
DomainRAS

RAP1A RAP1B

7.40e-0335692PS51421
DomainATPase_P-typ_cyto_domN

ATP2B1 ATP2B4

7.40e-0335692IPR023299
DomainP_typ_ATPase

ATP2B1 ATP2B4

7.81e-0336692IPR001757
DomainATPase_P-typ_P_site

ATP2B1 ATP2B4

7.81e-0336692IPR018303
DomainATPASE_E1_E2

ATP2B1 ATP2B4

7.81e-0336692PS00154
DomainATPase_P-typ_transduc_dom_A

ATP2B1 ATP2B4

8.24e-0337692IPR008250
DomainE1-E2_ATPase

ATP2B1 ATP2B4

8.24e-0337692PF00122
DomainSmall_GTPase_Ras

RAP1A RAP1B

8.24e-0337692IPR020849
DomainABC_transporter_CS

ABCA2 ABCA12

1.05e-0242692IPR017871
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

LDLRAP1 ANO2 ABCA2 SLC9A2 TRPC7 SLC16A3 SLC45A3 ABCA12 SLC15A4 SLC6A15 ATP2B1 ATP2B4 ANO3

9.77e-076815313MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

LDLRAP1 ANO2 ABCA2 SLC9A2 TRPC7 SLC16A3 SLC45A3 ABCA12 SLC15A4 SLC6A15 ATP2B1 ATP2B4 ANO3

2.33e-067365313M27287
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1E CACNA1H CACNA1G

8.43e-0523533M47666
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA1E CACNA1H CACNA1G

1.09e-0425533M47948
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

TRPC7 ATP2B1 ATP2B4

1.38e-0427533MM15053
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

TRPC7 ATP2B1 ATP2B4

1.54e-0428533M924
PathwayREACTOME_PLATELET_AGGREGATION_PLUG_FORMATION

RAP1A RAP1B ADRA2B

3.86e-0438533MM15456
PathwayREACTOME_PLATELET_AGGREGATION_PLUG_FORMATION

RAP1A RAP1B ADRA2B

4.17e-0439533M10735
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ANO2 TRPC7 ATP2B1 ATP2B4 ANO3

5.06e-04176535MM15718
PathwayREACTOME_NCAM1_INTERACTIONS

COL6A3 CACNA1H CACNA1G

5.19e-0442533M7169
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1E CACNA1H CACNA1G ATP2B1 ATP2B4

5.33e-04178535M2890
PathwayREACTOME_SMOOTH_MUSCLE_CONTRACTION

LMOD1 CACNA1H CACNA1G

5.57e-0443533M1429
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ANO2 TRPC7 ATP2B1 ATP2B4 ANO3

6.05e-04183535M997
PathwayREACTOME_MET_ACTIVATES_RAP1_AND_RAC1

RAP1A RAP1B

7.46e-0411532M27776
PathwayREACTOME_MET_ACTIVATES_RAP1_AND_RAC1

RAP1A RAP1B

7.46e-0411532MM15515
PathwayREACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS

ATP2B1 ATP2B4

8.94e-0412532M27326
PathwayREACTOME_MUSCLE_CONTRACTION

LMOD1 CACNA1H CACNA1G ATP2B1 ATP2B4

9.65e-04203535M5485
PathwayREACTOME_INDUCTION_OF_CELL_CELL_FUSION

ANO2 ANO3

1.05e-0313532M46426
PathwayREACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS

ATP2B1 ATP2B4

1.23e-0314532MM15052
PathwayREACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS

RAP1A RAP1B

1.41e-0315532M12101
PathwayREACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS

RAP1A RAP1B

1.41e-0315532M1262
PathwayREACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS

RAP1A RAP1B

1.41e-0315532MM14959
PathwayREACTOME_RAP1_SIGNALLING

RAP1A RAP1B

1.41e-0315532MM15019
PathwayREACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS

RAP1A RAP1B

1.41e-0315532MM14961
PathwayREACTOME_RAP1_SIGNALLING

RAP1A RAP1B

1.61e-0316532M923
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

COL6A3 CACNA1H CACNA1G

1.70e-0363533M11187
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCA2 ABCA12

1.82e-0317532MM14552
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC9A2 SLC16A3 SLC45A3 SLC15A4 SLC6A15

1.95e-03238535MM15076
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCA2 ABCA12

2.04e-0318532M524
PathwayWP_MAPK_SIGNALING

CACNA1E RAP1A RAP1B CACNA1H CACNA1G

2.25e-03246535M39597
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC9A2 SLC16A3 SLC45A3 SLC15A4 SLC6A15

2.38e-03249535M5988
PathwayREACTOME_PLATELET_HOMEOSTASIS

TRPC7 ATP2B1 ATP2B4

2.91e-0376533MM15051
PathwayKEGG_MAPK_SIGNALING_PATHWAY

CACNA1E RAP1A RAP1B CACNA1H CACNA1G

3.21e-03267535M10792
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1E TRPC7 CACNA1G ATP2B1 ATP2B4

1.36e-083870530786075
Pubmed

Developmental expression patterns of alpha1H T-type Ca2+ channels during spermatogenesis and organogenesis in mice.

CACNA1E CACNA1H CACNA1G

7.79e-08570312060068
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1E CACNA1H CACNA1G

2.72e-07770312900400
Pubmed

Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.

CACNA1E CACNA1H CACNA1G

4.34e-07870328330839
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1E CACNA1H CACNA1G

6.50e-07970316382099
Pubmed

Rap1A and rap1B ras-family proteins are prominently expressed in the nucleus of squamous carcinomas: nuclear translocation of GTP-bound active form.

RAP1A RAP1B

3.99e-06270213679863
Pubmed

Rap1 promotes endothelial mechanosensing complex formation, NO release and normal endothelial function.

RAP1A RAP1B

3.99e-06270225807985
Pubmed

Cav3.2 subunit underlies the functional T-type Ca2+ channel in murine hearts during the embryonic period.

CACNA1H CACNA1G

3.99e-06270214988077
Pubmed

[Feeling the pressure? Identification of two proteins activated by mechanical forces].

PIEZO2 PIEZO1

3.99e-06270221299953
Pubmed

Role of T-type calcium channel subunits in post-myocardial infarction remodelling probed with genetically engineered mice.

CACNA1H CACNA1G

3.99e-06270221622683
Pubmed

Functional and structural demonstration of the presence of Ca-ATPase (PMCA) in both microvillous and basal plasma membranes from syncytiotrophoblast of human term placenta.

ATP2B1 ATP2B4

3.99e-06270218657858
Pubmed

Non-Mendelian inheritance during inbreeding of Cav3.2 and Cav2.3 deficient mice.

CACNA1E CACNA1H

3.99e-06270233009476
Pubmed

Rap1 Is Essential for B-Cell Locomotion, Germinal Center Formation and Normal B-1a Cell Population.

RAP1A RAP1B

3.99e-06270234140948
Pubmed

Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development.

PIEZO2 PIEZO1

3.99e-06270238395992
Pubmed

CaV3.2 T-type Ca²⁺ channels in H₂S-mediated hypoxic response of the carotid body.

CACNA1H CTH

3.99e-06270225377087
Pubmed

Differential expression of PIEZO1 and PIEZO2 mechanosensitive channels in ocular tissues implicates diverse functional roles.

PIEZO2 PIEZO1

3.99e-06270237820892
Pubmed

Two separate Ni(2+) -sensitive voltage-gated Ca(2+) channels modulate transretinal signalling in the isolated murine retina.

CACNA1E CACNA1H

3.99e-06270221883984
Pubmed

Ca(v)3.2 T-type Ca2+ channel-dependent activation of ERK in paraventricular thalamus modulates acid-induced chronic muscle pain.

CACNA1H CACNA1G

3.99e-06270220685979
Pubmed

Mechanisms of mechanotransduction and physiological roles of PIEZO channels.

PIEZO2 PIEZO1

3.99e-06270239251883
Pubmed

Rap1B promotes VEGF-induced endothelial permeability and is required for dynamic regulation of the endothelial barrier.

RAP1A RAP1B

3.99e-06270229222111
Pubmed

Immunolocalization of the mechanogated ion channels PIEZO1 and PIEZO2 in human and mouse dental pulp and periodontal ligament.

PIEZO2 PIEZO1

3.99e-06270237975162
Pubmed

Purification and characterization of the 22,000-dalton GTP-binding protein substrate for ADP-ribosylation by botulinum toxin, G22K.

RAP1A RAP1B

3.99e-0627023141412
Pubmed

The influence of membrane lipid structure on plasma membrane Ca2+ -ATPase activity.

ATP2B1 ATP2B4

3.99e-06270216412504
Pubmed

Enhanced cortico-amygdala efficacy and suppressed fear in absence of Rap1.

RAP1A RAP1B

3.99e-06270218305243
Pubmed

Transduction of Repetitive Mechanical Stimuli by Piezo1 and Piezo2 Ion Channels.

PIEZO2 PIEZO1

3.99e-06270228636944
Pubmed

Distinct roles of PMCA isoforms in Ca2+ homeostasis of bladder smooth muscle: evidence from PMCA gene-ablated mice.

ATP2B1 ATP2B4

3.99e-06270216956963
Pubmed

Localization of two genes encoding plasma membrane Ca2(+)-transporting ATPases to human chromosomes 1q25-32 and 12q21-23.

ATP2B1 ATP2B4

3.99e-0627021674727
Pubmed

Mutation in RAP1 is a rare event in myelodysplastic syndromes.

RAP1A RAP1B

3.99e-06270216118622
Pubmed

T-type voltage-activated calcium channel Cav3.1, but not Cav3.2, is involved in the inhibition of proliferation and apoptosis in MCF-7 human breast cancer cells.

CACNA1H CACNA1G

3.99e-06270222469755
Pubmed

Piezo channels: from structure to function.

PIEZO2 PIEZO1

3.99e-06270225037583
Pubmed

Gender specific hippocampal whole genome transcriptome data from mice lacking the Cav2.3 R-type or Cav3.2 T-type voltage-gated calcium channel.

CACNA1E CACNA1H

3.99e-06270228393090
Pubmed

Piezo proteins: incidence and abundance in the enteric nervous system. Is there a link with mechanosensitivity?

PIEZO2 PIEZO1

3.99e-06270230324494
Pubmed

Mutation analysis of RAP1 gene in papillary thyroid carcinomas.

RAP1A RAP1B

3.99e-06270218948674
Pubmed

Chronic deficit in nitric oxide elicits oxidative stress and augments T-type calcium-channel contribution to vascular tone of rodent arteries and arterioles.

CACNA1H CACNA1G

3.99e-06270223436820
Pubmed

Expression of Rap 1 suppresses genomic instability of H-ras transformed mouse fibroblasts.

RAP1A RAP1B

3.99e-0627029330640
Pubmed

Different distribution of Cav3.2 and Cav3.1 transcripts encoding T-type Ca(2+) channels in the embryonic heart of mice.

CACNA1H CACNA1G

3.99e-06270221079360
Pubmed

Targeted ablation of plasma membrane Ca2+-ATPase (PMCA) 1 and 4 indicates a major housekeeping function for PMCA1 and a critical role in hyperactivated sperm motility and male fertility for PMCA4.

ATP2B1 ATP2B4

3.99e-06270215178683
Pubmed

Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo.

RAP1A RAP1B

3.99e-06270224039860
Pubmed

Deficiency of T-type Ca2+ channels Cav3.1 and Cav3.2 has no effect on angiotensin II-induced hypertension but differential effect on plasma aldosterone in mice.

CACNA1H CACNA1G

3.99e-06270231042060
Pubmed

The Rap1 small GTPase is a critical mediator of the effects of stress on prefrontal cortical dysfunction.

RAP1A RAP1B

3.99e-06270232651478
Pubmed

Gut-derived GIP activates central Rap1 to impair neural leptin sensitivity during overnutrition.

RAP1A RAP1B

3.99e-06270231403469
Pubmed

Mechanosensitive channels: in touch with Piezo.

PIEZO2 PIEZO1

3.99e-06270221056836
Pubmed

Loss of stretch-activated channels, PIEZOs, accelerates non-small cell lung cancer progression and cell migration.

PIEZO2 PIEZO1

3.99e-06270230745454
Pubmed

The Ca(v)3.1 T-type calcium channel is required for neointimal formation in response to vascular injury in mice.

CACNA1H CACNA1G

3.99e-06270222886848
Pubmed

The role of PIEZO ion channels in the musculoskeletal system.

PIEZO2 PIEZO1

3.99e-06270236717101
Pubmed

Astrocytes in the optic nerve head express putative mechanosensitive channels.

PIEZO2 PIEZO1

3.99e-06270226236150
Pubmed

Touch, Tension, and Transduction - The Function and Regulation of Piezo Ion Channels.

PIEZO2 PIEZO1

3.99e-06270227743844
Pubmed

Axonal and Glial PIEZO1 and PIEZO2 Immunoreactivity in Human Clitoral Krause's Corpuscles.

PIEZO2 PIEZO1

3.99e-06270238928429
Pubmed

A hydrophobic gate in the inner pore helix is the major determinant of inactivation in mechanosensitive Piezo channels.

PIEZO2 PIEZO1

3.99e-06270230628892
Pubmed

Role of plasma membrane Ca2+-ATPase in contraction-relaxation processes of the bladder: evidence from PMCA gene-ablated mice.

ATP2B1 ATP2B4

3.99e-06270216291816
Pubmed

Regulation of plasma membrane Ca2+-ATPase by small GTPases and phosphoinositides in human platelets.

ATP2B1 ATP2B4

3.99e-06270210748016
Pubmed

Piezo1 ion channel pore properties are dictated by C-terminal region.

PIEZO2 PIEZO1

3.99e-06270226008989
Pubmed

Deletion of T-type calcium channels Cav3.1 or Cav3.2 attenuates endothelial dysfunction in aging mice.

CACNA1H CACNA1G

3.99e-06270229082441
Pubmed

Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis.

RAP1A RAP1B

3.99e-06270218805968
Pubmed

Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo.

RAP1A RAP1B

3.99e-06270226804993
Pubmed

Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels.

PIEZO2 PIEZO1

3.99e-06270220813920
Pubmed

Selective upregulation of the expression of plasma membrane calcium ATPase isoforms upon differentiation and 1,25(OH)2D3-vitamin treatment of colon cancer cells.

ATP2B1 ATP2B4

3.99e-06270226116539
Pubmed

Rap1-GTPases control mTORC1 activity by coordinating lysosome organization with amino acid availability.

RAP1A RAP1B

3.99e-06270232184389
Pubmed

The rap GTPases regulate B cell morphology, immune-synapse formation, and signaling by particulate B cell receptor ligands.

RAP1A RAP1B

3.99e-06270218191594
Pubmed

[Decreased mRNA expressions of T-type channel alpha1H and alpha1G in the sperm of varicocele patients and their implication].

CACNA1H CACNA1G

3.99e-06270222574369
Pubmed

A Plug-and-Latch Mechanism for Gating the Mechanosensitive Piezo Channel.

PIEZO2 PIEZO1

3.99e-06270232142647
Pubmed

Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception.

PIEZO2 PIEZO1

3.99e-06270234464353
Pubmed

Chromosome mapping of the human RAS-related RAP1A, RAP1B, and RAP2 genes to chromosomes 1p12----p13, 12q14, and 13q34, respectively.

RAP1A RAP1B

3.99e-0627022108841
Pubmed

Blockade of T-type Ca(2+) channels inhibits human ovarian cancer cell proliferation.

CACNA1H CACNA1G

3.99e-06270221438841
Pubmed

Plasma membrane calcium ATPase regulates bone mass by fine-tuning osteoclast differentiation and survival.

ATP2B1 ATP2B4

3.99e-06270223266958
Pubmed

Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins.

RAP1A RAP1B

3.99e-06270218056377
Pubmed

β-Adrenergic stimulation increases Cav3.1 activity in cardiac myocytes through protein kinase A.

CACNA1H CACNA1G

3.99e-06270222808078
Pubmed

Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasis.

RAP1A RAP1B

3.99e-06270230796637
Pubmed

Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions.

RAP1A RAP1B

3.99e-06270218625726
Pubmed

Protein kinase A-dependent phosphorylation of Rap1 regulates its membrane localization and cell migration.

RAP1A RAP1B

3.99e-06270223946483
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

COL6A3 ABCA2 ABCA12 MTERF1 ZGRF1 CACNA1H TECTA CSMD3

8.99e-0651370825798074
Pubmed

Podocyte-specific RAP1GAP expression contributes to focal segmental glomerulosclerosis-associated glomerular injury.

RAP1A RAP1B

1.20e-05370224642466
Pubmed

Rap1 signaling prevents L-type calcium channel-dependent neurotransmitter release.

RAP1A RAP1B

1.20e-05370223616533
Pubmed

5,6-EET potently inhibits T-type calcium channels: implication in the regulation of the vascular tone.

CACNA1H CACNA1G

1.20e-05370224327205
Pubmed

Rap1 small GTPase is essential for maintaining pulmonary endothelial barrier function in mice.

RAP1A RAP1B

1.20e-05370238010922
Pubmed

Ethanol inhibition of a T-type Ca²+ channel through activity of protein kinase C.

CACNA1H CACNA1G

1.20e-05370223488970
Pubmed

Differential effect of T-type voltage-gated Ca2+ channel disruption on renal plasma flow and glomerular filtration rate in vivo.

CACNA1H CACNA1G

1.20e-05370224966091
Pubmed

T-type channels: release a brake, engage a gear.

CACNA1H CACNA1G

1.20e-05370226488564
Pubmed

Small GTPase Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature.

RAP1A RAP1B

1.20e-05370226714318
Pubmed

Differential interactions of Na+ channel toxins with T-type Ca2+ channels.

CACNA1H CACNA1G

1.20e-05370218591418
Pubmed

Large Extracellular Vesicle-Associated Rap1 Accumulates in Atherosclerotic Plaques, Correlates With Vascular Risks and Is Involved in Atherosclerosis.

RAP1A RAP1B

1.20e-05370232539601
Pubmed

Identification of the t-type calcium channel (Ca(v)3.1d) in developing mouse heart.

CACNA1H CACNA1G

1.20e-05370211230107
Pubmed

Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation.

CACNA1H CACNA1G

1.20e-05370228846697
Pubmed

Sequential activation of Rap1 and Rac1 small G proteins by PDGF locally at leading edges of NIH3T3 cells.

RAP1A RAP1B

1.20e-05370218422604
Pubmed

Caveolin-3 regulates protein kinase A modulation of the Ca(V)3.2 (alpha1H) T-type Ca2+ channels.

CACNA1H CACNA1G

1.20e-05370221084288
Pubmed

Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures.

CACNA1H CACNA1G

1.20e-05370233547341
Pubmed

Calmodulin regulates Cav3 T-type channels at their gating brake.

CACNA1H CACNA1G

1.20e-05370228972185
Pubmed

A complex of Neuroplastin and Plasma Membrane Ca2+ ATPase controls T cell activation.

ATP2B1 ATP2B4

1.20e-05370228827723
Pubmed

Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability.

CACNA1H CACNA1G

1.20e-05370211927664
Pubmed

Rap1 and its effector RIAM are required for lymphocyte trafficking.

RAP1A RAP1B

1.20e-05370226324702
Pubmed

ZnT-1 enhances the activity and surface expression of T-type calcium channels through activation of Ras-ERK signaling.

CACNA1H CACNA1G

1.20e-05370222572848
Pubmed

Mechanically Activated Piezo Channels Mediate Touch and Suppress Acute Mechanical Pain Response in Mice.

PIEZO2 PIEZO1

1.20e-05370230726728
Pubmed

Plasma membrane Ca2+ ATPase 1 (PMCA1) but not PMCA4 is critical for B-cell development and Ca2+ homeostasis in mice.

ATP2B1 ATP2B4

1.20e-05370233098669
Pubmed

Exploring Piezo1, Piezo2, and TMEM150C in human brain tissues and their correlation with brain biomechanical characteristics.

PIEZO2 PIEZO1

1.20e-05370238124148
Pubmed

Otoancorin, an inner ear protein restricted to the interface between the apical surface of sensory epithelia and their overlying acellular gels, is defective in autosomal recessive deafness DFNB22.

OTOA TECTA

1.20e-05370211972037
Pubmed

Dual functions of Rap1 are crucial for T-cell homeostasis and prevention of spontaneous colitis.

RAP1A RAP1B

1.20e-05370226634692
Pubmed

Structural basis for small G protein effector interaction of Ras-related protein 1 (Rap1) and adaptor protein Krev interaction trapped 1 (KRIT1).

RAP1A RAP1B

1.20e-05370222577140
Pubmed

T-type, but not L-type, voltage-gated calcium channels are dispensable for lymphatic pacemaking and spontaneous contractions.

CACNA1H CACNA1G

1.20e-05370231919478
Pubmed

Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria.

CACNA1H CACNA1G

1.20e-05370225825486
Pubmed

Myotubularin related protein-2 and its phospholipid substrate PIP2 control Piezo2-mediated mechanotransduction in peripheral sensory neurons.

PIEZO2 PIEZO1

1.20e-05370229521261
Cytoband12q21.3

SLC6A15 ATP2B1

6.87e-06370212q21.3
CytobandEnsembl 112 genes in cytogenetic band chr1q32

SLC45A3 LMOD1 ATP2B4 RPS6KC1

1.03e-03290704chr1q32
GeneFamilyCalcium voltage-gated channel subunits

CACNA1E CACNA1H CACNA1G

4.95e-0526503253
GeneFamilySolute carriers

SLC9A2 SLC16A3 SLC45A3 SLC15A4 SLC6A15 SLC35A5 SLC35B1

1.00e-04395507752
GeneFamilyATPases Ca2+ transporting

ATP2B1 ATP2B4

2.67e-0495021209
GeneFamilyAnoctamins

ANO2 ANO3

3.33e-0410502865
GeneFamilyATP binding cassette subfamily A

ABCA2 ABCA12

6.68e-0414502805
GeneFamilyRAS type GTPase family

RAP1A RAP1B

3.31e-0331502389
GeneFamilyCollagens

COL6A3 COL12A1

7.18e-0346502490
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA ANO2 COL12A1 PIEZO2 ABCA12 CSMD3 ANO3

1.49e-081846972cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA ANO2 COL12A1 PIEZO2 ABCA12 CSMD3 ANO3

1.49e-08184697ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA ANO2 COL12A1 PIEZO2 ABCA12 CSMD3 ANO3

1.49e-081846972b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

VIPR1 ANO2 ADRA2B ATP2B1 KCNH4

1.33e-077769510969743351c49a1d6d8ae1ef93098e7786ca3fe
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

VIPR1 COL6A3 ADRA2B COL12A1 LMOD1 ANO3

6.41e-07198696bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1|Striatum / BrainAtlas - Mouse McCarroll V32

VIPR1 ADRA2B ATP2B1 ANO3 KCNH4

3.19e-061466957b863f9bc63dc1afe015a18a70cd6ed0b71d1f09
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADRA2B COL12A1 PIEZO2 PLCL1 ANO3

3.65e-061506958645b9c7f9511ed6cc9afe04440c2873a3094150
ToppCellGlobus_pallidus-Neuronal-Excitatory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CACNA1E VIPR1 ATP2B1 ANO3 KCNH4

5.00e-06160695f843287ed57d2d5a3b3f6dfb03b6934e330e6645
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CACNA1E VIPR1 ATP2B1 ANO3 KCNH4

5.15e-06161695ebcd5066e82b7760b9da6adc02d11258d1309dab
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 PIEZO2 LMOD1 ANO3

5.47e-06163695bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 PIEZO2 LMOD1 ANO3

5.47e-061636958e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)|Hippocampus / BrainAtlas - Mouse McCarroll V32

CACNA1E VIPR1 SLC9A2 CACNA1H ATP2B1

6.34e-061686956db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 LMOD1 DAAM1 ANO3

6.71e-06170695fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 LMOD1 DAAM1 ANO3

6.71e-0617069503044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E RAP1A SRPRA CACNA1H SLC35B1

8.16e-06177695f0487e3b439f7803e465cad44916e2e271f33d6d
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR1 SLC9A2 LMOD1 CACNA1G PLCL1

8.85e-0618069578fdcfb3fdbf36469cae78407cda5bd0996930d8
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A3 COL12A1 PIEZO2 DNER PLCL1

9.34e-061826953dfa9187e9d2bab1d199079d29209c4648220ada
ToppCellFrontal_cortex-Neuronal-Excitatory|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CACNA1E VIPR1 ATP2B1 ATP2B4 ANO3

9.85e-061846956e17c8151d6dc543de16d804db956c63c3fda414
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR1 SLC9A2 LMOD1 CACNA1G PLCL1

9.85e-06184695f4344f3c407b2d4d703fe56e43d84dbfe60ba833
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA2B LMOD1 CACNA1H CACNA1G PLCL1

1.01e-0518569530df02fbe2828e3c4f3e5c4cda855e74fb31be39
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

COL6A3 COL12A1 PIEZO2 LMOD1 PLCL1

1.04e-05186695cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA2B LMOD1 CACNA1H CACNA1G PLCL1

1.06e-051876958ff9f771d10c372d771c92dfa9006aa81aec4681
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 PIEZO2 LMOD1 ANO3

1.15e-0519069570c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMOD1 CACNA1H PLCL1 DAAM1 BTBD3

1.15e-051906951ab3f19f1ce9f58e5125135704d94655a2e330a0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 PIEZO2 LMOD1 ANO3

1.18e-05191695107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 LMOD1 CACNA1H ANO3

1.18e-0519169504c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 PIEZO2 LMOD1 ANO3

1.18e-05191695bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 PIEZO2 LMOD1 ANO3

1.21e-05192695d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA2B LMOD1 CACNA1H PLCL1 BTBD3

1.27e-05194695b8a130ffae68ffe550bf335460a1ec1035cf8d8d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 PIEZO2 LMOD1 DAAM1

1.34e-051966952b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 LMOD1 DAAM1 ANO3

1.37e-0519769580e153790cef37b743e22a7370ff5b3a6abf147d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCA2 PIEZO2 SLC45A3 SLC6A15 PLCL1

1.47e-05200695091a18d6efed81cab99955c3047f172170f70476
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCA2 PIEZO2 SLC45A3 SLC6A15 PLCL1

1.47e-052006953b8513defe25262ab4b492345b2628570eaefd17
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

CACNA1E VIPR1 CACNA1H ATP2B1

8.02e-051476948f725ff8fb4ced5db2643e80669d3f7945b820ab
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ANO2 ABCA12 CSMD3 ANO3

8.45e-05149694c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ANO2 ABCA12 CSMD3 ANO3

8.45e-05149694a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Teffector/EM_CD4|GI_large-bowel / Manually curated celltypes from each tissue

PIEZO1 ZNF221 PLCL1 MED12

1.01e-0415669401f2c0c6a936dfb59bc727feef428a906ad2a80b
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 ERP27 ABCA12 CSMD3

1.14e-04161694b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 ERP27 ABCA12 CSMD3

1.14e-04161694f7a89c481f789f624102857be722c95fbeb47595
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 PLCL1 ANO3

1.14e-041616941b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellControl-Epithelial-Ionocyte|World / Disease state, Lineage and Cell class

CFAP20DC SLC9A2 ADRA2B CACNA1H

1.17e-04162694e3b9b46ce2faff7d099502df14bbf51e9f183f8c
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMOD1 CACNA1H CACNA1G TMEM255B

1.17e-0416269422f1abd20f43bc7e7fc46969da9962faf70ae5d2
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMOD1 CACNA1H CACNA1G TMEM255B

1.17e-04162694966df4558140c3d541999ab553f201ae76a1c401
ToppCellControl-Epithelial-Ionocyte|Control / Disease state, Lineage and Cell class

CFAP20DC SLC9A2 ADRA2B CACNA1H

1.19e-04163694bf09fa39bf3e6b3a776d5e79c30c96df572956a3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 PLCL1 ANO3

1.25e-04165694e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 PLCL1 ANO3

1.25e-04165694b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 PLCL1 ANO3

1.25e-04165694d8f8b088fd28a6b9dbd6b51bcaee42000e963321
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A2 ABCA12 GRINA ATP2B1

1.28e-0416669422b31acbbef1936ce19b393cf880c63ea2fa0f1b
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E LMOD1 CACNA1G CSMD3

1.31e-04167694e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCellfacs-Large_Intestine-Proximal|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROM1 SLC9A2 ABCA12 ATP2B1

1.34e-0416869423e0e1592d7400012d289adb10c7598285bae2e9
ToppCellfacs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l26|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANO2 ERP27 SLC45A3 PLCL1

1.40e-041706944b1c84b35b7242a297ffdb9c23a6d982acf1bed5
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROM1 SLC9A2 ABCA12 ATP2B1

1.44e-041716945d0d6c1ff610a703ae0b834a12823c5ff9012932
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 ZGRF1 ANO3

1.44e-04171694b0373ed8283ee1792b6a490bff93906546978593
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 ZGRF1 ANO3

1.44e-04171694b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 PLCL1 ANO3

1.47e-0417269408a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 PLCL1 ANO3

1.47e-04172694553701349444eb366df3c11f54bb093434f153c6
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

ZNF189 DAAM1 GRINA MED12

1.50e-04173694090dc3c5bd2652a65c2490fc889da858c3af368f
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZNF189 DAAM1 GRINA MED12

1.54e-04174694a79ebb01a5849c314e02594a9c95009dbb03cb8c
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLXNA3 COL12A1 ERP27 LMOD1

1.54e-04174694a7ade7372e83edd4e3983e77f8417b51f0b47340
ToppCellControl-Stromal-Pericyte|Control / Disease state, Lineage and Cell class

COL6A3 PRSS37 LMOD1 CACNA1H

1.54e-0417469491fc1f1c891f105a91968c22e2de5321c52b439a
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANO2 ERP27 SLC16A3 TMEM255B

1.54e-041746944a18b51501eaaeb7907e99316ba8ae15b2c7d529
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 COL12A1 LMOD1 ANO3

1.57e-041756941799a7be623dc3bf53ba580a7c47d2619969d708
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E LMOD1 CACNA1G CSMD3

1.57e-0417569459249c9e83952d7277010e7be3c779e26399eb5d
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 ERP27 ABCA12 CSMD3

1.57e-041756947329ebb135fc4311ee9595729b62a5d152c9de8c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 LMOD1 ANO3

1.57e-04175694795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E LMOD1 CACNA1G CSMD3

1.57e-04175694b35cc1357495f2a03a6500f807c6e6f8c877734d
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROM1 SLC9A2 ABCA12 ATP2B1

1.60e-041766947622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A3 PIEZO2 CACNA1G PLCL1

1.64e-04177694bd602db857f37869ef76d14c05ef522c509f08ee
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 PIEZO2 LMOD1

1.68e-0417869478a0c6340001a77f5b2d890b6263f574af2e72da
ToppCellfacs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA2B ERP27 LMOD1 CACNA1G

1.75e-04180694a37cc885fe3f6cb9df69d43358064c83c18412e7
ToppCellfacs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA2B ERP27 LMOD1 CACNA1G

1.75e-0418069463a6d532b16b8b15c7c9102148d7297ee3afd641
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VIPR1 COL12A1 TECTA ANO3

1.75e-04180694e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GJA3 COL6A3 COL12A1 PIEZO2

1.79e-04181694a2058d658f07ab6f0a28d2622f3090b4cde6f763
ToppCellnormal_Lung-Fibroblasts-Pericytes|normal_Lung / Location, Cell class and cell subclass

COL6A3 COL12A1 LMOD1 CACNA1H

1.79e-04181694f74941e49950027360d71ea3b205fc20c6929766
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GJA3 COL6A3 COL12A1 PIEZO2

1.79e-04181694526e858a848470b6d2d5248788004d9735ed3add
ToppCellfacs-Heart-LV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA2B PLCL1 DAAM1 BTBD3

1.79e-041816941db1eb7d330a7e5090994007ae287e11f0a74450
ToppCellfacs-Heart-LV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA2B PLCL1 DAAM1 BTBD3

1.79e-0418169406174ce9240c9261c0f51a1b0d875335d60722e5
ToppCellCOVID-19-Heart-EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANO2 LMOD1 CACNA1H PLCL1

1.82e-04182694e67f3234165199085c793915ebb1f9bbd845e933
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VIPR1 COL12A1 TECTA ANO3

1.82e-0418269472e65a23cd36085bc880087d3cae92395de918a1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 LMOD1 ANO3

1.82e-0418269444764676ed3f51ba171ce63f669390392fa50a43
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 LMOD1 ANO3

1.82e-04182694d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VIPR1 COL12A1 TECTA ANO3

1.82e-0418269405c167158815bf25d509df59ab386e1990712765
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMOD1 SLC6A15 DAAM1 BTBD3

1.86e-041836944060d979948e1dd7507977629a7fbdfa4ca65bb6
ToppCellfacs-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM255B ATP2B4 KCNH4 BTBD3

1.86e-0418369412e876d6205af8aad74265c668b5e95b9e7487f3
ToppCelltumor_Lung-Fibroblasts-Pericytes|tumor_Lung / Location, Cell class and cell subclass

COL6A3 COL12A1 LMOD1 CACNA1H

1.86e-04183694a03dd563af9b15cb1f5de5732a229405a9f82d84
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMOD1 SLC6A15 DAAM1 BTBD3

1.86e-041836940d44a978221cf3f733704bf11863502805fba733
ToppCellfacs-Heart-RV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA2B PLCL1 DAAM1 BTBD3

1.90e-041846949c20b50f8d6ac689d41d5440c835f9db8d04758b
ToppCellMesenchymal_cells-Chondrocytes|World / Lineage and Cell class

COL6A3 COL12A1 CTH NIBAN2

1.90e-041846941e03f9f08de5ad4d45388a95afad9f23ff0d0e28
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 COL12A1 LMOD1 ANO3

1.90e-04184694e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellPosterior_cortex-Neuronal-Excitatory|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CACNA1E VIPR1 ATP2B1 ANO3

1.90e-0418469425ccf08a8a26d7e7827b6357f33a53aaf423577d
ToppCellMesenchymal_cells-Smooth_muscle|Mesenchymal_cells / Lineage and Cell class

LMOD1 CACNA1H TMEM255B BTBD3

1.90e-0418469483987abaedc26e6da477bc70d65e10b1ab1aea60
ToppCellfacs-Heart-RV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA2B PLCL1 DAAM1 BTBD3

1.90e-0418469431dbe6119a3bcd266ae5e9b340c853d9ff680dce
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 LMOD1 ANO3

1.94e-041856947092436b4db90289516ed130ade596e3021cffaf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 LMOD1 ANO3

1.94e-0418569451dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR1 COL6A3 ADRA2B PIEZO2

1.94e-04185694f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 LMOD1 CACNA1H ATP2B4

1.94e-0418569438486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 LMOD1 ANO3

1.94e-04185694a8ca7819066d5297ef6966e7f3e2c9f8a7673fdc
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR1 COL6A3 ADRA2B PIEZO2

1.94e-0418569440e958511790e84321da5ccf735f9974c06a0263
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR1 COL6A3 ADRA2B PIEZO2

1.94e-041856945f2eeba80aff145e85cfd81e2890a155406badb9
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

VIPR1 LMOD1 CACNA1H PLCL1

1.94e-04185694ba5baa4d7f097108622674de5b7f4fd279843d24
Drug3,4-dihydroquinazoline

CACNA1E CACNA1H CACNA1G

5.53e-076703CID000583065
Drugnimodipine

CACNA1E CACNA1H CACNA1G GRINA ATP2B1 ATP2B4

5.64e-06145706CID000004497
DrugAC1L2VU3

CACNA1E CACNA1H CACNA1G

6.00e-0612703CID000129572
Drugcaloxin 1b1

ATP2B1 ATP2B4

9.32e-062702ctd:C510327
Drugpentasulfane

CACNA1E CACNA1H CACNA1G

1.51e-0516703CID000448216
Drugcamphorsulfonic acid

LMOD1 PLCL1

2.79e-053702CID000018462
Drug1,3-dioxoisoindoline-5-carboxamide

CACNA1H CACNA1G

2.79e-053702CID010679219
Drugradicicol; Up 200; 0.1uM; MCF7; HG-U133A

UBXN4 ZNF189 DAAM1 RBM28 ATP2B1 ATP2B4

3.04e-05195706325_UP
DrugIAA-94

CACNA1E GJA3 CACNA1H CACNA1G

3.75e-0561704CID000003667
Drugpimozide

CACNA1E ADRA2B TRPC7 CACNA1H CACNA1G

4.52e-05127705CID000016362
DrugAC1L1TJF

CACNA1E CACNA1H CACNA1G ATP2B1

5.11e-0566704CID000003377
Drugalfuzosin

CACNA1E ADRA2B LMOD1

6.10e-0525703CID000002092
Druglanthanum

CACNA1E CACNA1H CACNA1G ATP2B1 ATP2B4

6.26e-05136705CID000023926
DiseaseKabuki make-up syndrome

RAP1A RAP1B

3.22e-054692C0796004
DiseaseBethlem myopathy (is_implicated_in)

COL6A3 COL12A1

3.22e-054692DOID:0050663 (is_implicated_in)
DiseaseUllrich congenital muscular dystrophy

COL6A3 COL12A1

3.22e-054692cv:C4551860
DiseaseBethlem myopathy

COL6A3 COL12A1

3.22e-054692cv:C1834674
DiseaseBETHLEM MYOPATHY 1

COL6A3 COL12A1

3.22e-054692C1834674
DiseaseUllrich congenital muscular dystrophy (is_implicated_in)

COL6A3 COL12A1

3.22e-054692DOID:0050558 (is_implicated_in)
DiseaseUllrich congenital muscular dystrophy 1

COL6A3 COL12A1

3.22e-054692C0410179
DiseaseHailey-Hailey disease (implicated_via_orthology)

ATP2B1 ATP2B4

8.03e-056692DOID:0050429 (implicated_via_orthology)
Diseasepericalcarine cortex volume measurement

GJA3 PLCL1

2.92e-0411692EFO_0010322
DiseaseDystonia, Limb

COL6A3 ANO3

7.16e-0417692C0751093
DiseaseDystonia, Diurnal

COL6A3 ANO3

7.16e-0417692C0393610
DiseaseDystonia, Paroxysmal

COL6A3 ANO3

8.05e-0418692C0393588
DiseaseDystonia

CACNA1E COL6A3 ANO3

1.09e-0386693C0013421
Diseasesystemic mastocytosis

CACNA1E ABCA2

1.56e-0325692MONDO_0016586
Diseasemalate measurement

SLC16A3 SLC6A15

2.25e-0330692EFO_0010508

Protein segments in the cluster

PeptideGeneStartEntry
SIAVPKEFVVFGQFV

CSMD3

1791

Q7Z407
FIFAVIAVQLFKGKF

CACNA1E

1301

Q15878
FVQVFVKFSVGLDAV

ABCA12

871

Q86UK0
RGEVVKAFVVLASQF

ACSM2A

501

Q08AH3
FRQVASEFGLKISFV

CTH

121

P32929
SIQFAVDKRVFIAGF

BTBD3

396

Q9Y2F9
EKRFTFVLAVVIGVF

ADRA2B

366

P18089
GKFSVISNAFVIAIT

ANO2

811

Q9NQ90
FVKFFIIGVTVLVVA

ATP2B1

416

P20020
VVVFTLLFAGEKFFD

ATP2B1

941

P20020
FVKFFIIGITVLVVA

ATP2B4

406

P23634
FIIVFEHLVFGIKSF

ANO3

916

Q9BYT9
KSALTVQFVQGIFVE

RAP1A

16

P62834
KSALTVQFVQGIFVE

RAP1B

16

P61224
FSKFGTIVNIQVAFK

RBM27

621

Q9P2N5
KTVFAQFGAVLEVNI

RBM28

131

Q9NW13
LQFIIDAFKGQVFVL

PUM2

866

Q8TB72
QGFTEVRDVFFKEVT

NIBAN2

356

Q96TA1
AVTLTVAQAFKVAFE

LDLRAP1

156

Q5SW96
IVEIQGAFFKEVSLF

OTOA

521

Q7RTW8
RISKLVVFVAGFNVF

OR5B21

191

A6NL26
SVFTFVAEVKGFVRE

GRINA

181

Q7Z429
AVSVFFKELIQEFGI

SLC16A3

41

O15427
FAKGIVFGRFDETVI

RPS6KC1

81

Q96S38
VTGEVFVGAVNRVFK

PLXNA3

41

P51805
FTEALEFNTVVKLFA

LMOD1

351

P29536
SKAGCVAQVFLVVFF

OR14C36

91

Q8NHC7
QVNKIYGLFVAFTVA

OR52A1

196

Q9UKL2
GEVVLFLFSFKDITQ

KCNH4

121

Q9UQ05
VDGAVFAVLKAVFVL

MED12

1216

Q93074
VKVFSRIFGEVAVAT

PRSS37

181

A4D1T9
KGFVVEVNTTFEDFV

PRPF40A

686

O75400
GDKFVSVVSQFITVA

DAAM1

921

Q9Y4D1
FVFVGTKDSIANATV

FMR1

401

Q06787
TVIFVLESVFKLVAF

CACNA1G

1651

O43497
KVVKFIFNTVGGFDE

COL12A1

2341

Q99715
SKVRVGVVQFSNDVF

COL6A3

1471

P12111
VILKANETFAFVGNV

ABCA2

471

Q9BZC7
EFIAATEVAVIGFFQ

ERP27

51

Q96DN0
FNIIFKTLFEVGFIA

GJA3

151

Q9Y6H8
FTIVFVFEAALKLVA

CACNA1H

1656

O95180
FIGFVNDSVTKSIVA

DNER

281

Q8NFT8
KFTGRVEFIFVNVEN

RNF103

256

O00237
AFVVFLCGQSVFITK

SLC15A4

236

Q8N697
QVIGFGSVKIAAFIA

MFSD14B

281

Q5SR56
QHKENFFVFKIVIVG

OR1E3

306

Q8WZA6
QVLTVLFFLEVVGFK

TMEM67

691

Q5HYA8
VSFVKKNVLVTGGFF

FUNDC2

166

Q9BWH2
VVFAVLGFKANVINE

SLC6A15

351

Q9H2J7
VAAIVFISFGVVAAF

TMEM255B

86

Q8WV15
VVLTFVFGANVEKLI

PROM1

501

O43490
FVIGNGKNLVDFTFV

NSDHL

226

Q15738
VINAVFAKILIQFFD

SLC35B1

61

P78383
GLVAIYFATQVVFDK

SLC45A3

531

Q96JT2
IFKGAVFQSLDGIVV

CFAP20DC

21

Q6ZVT6
GKINIFSFGFHVVVE

TECTA

1196

O75443
KSALTVQFVQGIFVE

nan

16

A6NIZ1
VSFRSVIEVINKFAF

PLCL1

466

Q15111
LGFQVIFTDFKVVNV

TBPL1

91

P62380
KGLLTFEDVAVFFTQ

ZNF189

11

O75820
VFELVVGSFQGFVVA

VIPR1

371

P32241
FVTAFQGLSVAFILK

SLC35A5

311

Q9BS91
IETIDVFAGIANFFV

SLC9A2

266

Q9UBY0
SVVLVIGKFVREFFS

PIEZO2

2676

Q9H5I5
AENIFKSVSFRLFGV

MTERF1

46

Q99551
QFELVFVVGFQKILT

SRPRA

61

P08240
FKEAVTFKDVAVVFT

ZNF221

26

Q9UK13
VVILFFVQLFEKSEA

ZGRF1

1666

Q86YA3
FTEIAVVVKYLFQFG

PIEZO1

1736

Q92508
AIATAKRSGAVFVVF

UBXN4

11

Q92575
QSIAVKFLAVFGVSI

TRPC7

346

Q9HCX4
VVGFILIFTFFNIKG

XKR9

266

Q5GH70