Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein antigen binding	PPP2R1A HLA-DQB2 SIRPA	3.22e-05	16	79	3	GO:1990405
GeneOntologyMolecularFunction	extracellular matrix constituent, lubricant activity	MUC17 MUC3A	9.23e-05	4	79	2	GO:0030197
GeneOntologyMolecularFunction	extracellular matrix structural constituent	SLIT2 HSPG2 COL12A1 HMCN1 MUC17 MUC3A	1.01e-04	188	79	6	GO:0005201
GeneOntologyCellularComponent	postsynaptic density	NPTN ARHGAP32 LRFN2 PTPRF ANK3 RPS3 TSC1 RTN1 EPHA4	4.57e-05	451	78	9	GO:0014069
GeneOntologyCellularComponent	asymmetric synapse	NPTN ARHGAP32 LRFN2 PTPRF ANK3 RPS3 TSC1 RTN1 EPHA4	7.03e-05	477	78	9	GO:0032279
GeneOntologyCellularComponent	postsynaptic specialization	NPTN ARHGAP32 LRFN2 PTPRF ANK3 RPS3 TSC1 RTN1 EPHA4	1.05e-04	503	78	9	GO:0099572
GeneOntologyCellularComponent	neuron to neuron synapse	NPTN ARHGAP32 LRFN2 PTPRF ANK3 RPS3 TSC1 RTN1 EPHA4	1.41e-04	523	78	9	GO:0098984
GeneOntologyCellularComponent	cell surface	HSPD1 SLIT2 HAVCR1 NPTN LRFN2 ANK3 CLU MUC17 HLA-DQB2 NCAM1 SIRPA FCRL5 EPHA4	2.21e-04	1111	78	13	GO:0009986
GeneOntologyCellularComponent	growth cone	TSHZ3 PTPRF CLU NCAM1 TSC1 EPHA4	3.10e-04	245	78	6	GO:0030426
GeneOntologyCellularComponent	site of polarized growth	TSHZ3 PTPRF CLU NCAM1 TSC1 EPHA4	3.67e-04	253	78	6	GO:0030427
Domain	-	HAVCR1 HSPG2 NPTN COL12A1 LRFN2 PTPRF HMCN1 LRIG1 HLA-DQB1 HLA-DQB2 NCAM1 SIGLEC1 SIRPA FCRL5 LRIT1 EPHA4	9.68e-09	663	77	16	2.60.40.10
Domain	IG_LIKE	HAVCR1 HSPG2 NPTN LRFN2 PTPRF HMCN1 LRIG1 HLA-DQB1 HLA-DQB2 NCAM1 SIGLEC1 SIRPA FCRL5 LRIT1	1.16e-08	491	77	14	PS50835
Domain	Ig-like_dom	HAVCR1 HSPG2 NPTN LRFN2 PTPRF HMCN1 LRIG1 HLA-DQB1 HLA-DQB2 NCAM1 SIGLEC1 SIRPA FCRL5 LRIT1	1.57e-08	503	77	14	IPR007110
Domain	Ig-like_fold	HAVCR1 HSPG2 NPTN COL12A1 LRFN2 PTPRF HMCN1 LRIG1 HLA-DQB1 HLA-DQB2 NCAM1 SIGLEC1 SIRPA FCRL5 LRIT1 EPHA4	2.33e-08	706	77	16	IPR013783
Domain	IGc2	HSPG2 NPTN LRFN2 PTPRF HMCN1 LRIG1 NCAM1 SIGLEC1 FCRL5 LRIT1	4.31e-08	235	77	10	SM00408
Domain	Ig_sub2	HSPG2 NPTN LRFN2 PTPRF HMCN1 LRIG1 NCAM1 SIGLEC1 FCRL5 LRIT1	4.31e-08	235	77	10	IPR003598
Domain	Ig_I-set	HSPG2 NPTN LRFN2 PTPRF HMCN1 LRIG1 NCAM1 SIGLEC1 LRIT1	8.58e-08	190	77	9	IPR013098
Domain	I-set	HSPG2 NPTN LRFN2 PTPRF HMCN1 LRIG1 NCAM1 SIGLEC1 LRIT1	8.58e-08	190	77	9	PF07679
Domain	IG	HAVCR1 HSPG2 NPTN LRFN2 PTPRF HMCN1 LRIG1 NCAM1 SIGLEC1 SIRPA FCRL5 LRIT1	1.44e-07	421	77	12	SM00409
Domain	Ig_sub	HAVCR1 HSPG2 NPTN LRFN2 PTPRF HMCN1 LRIG1 NCAM1 SIGLEC1 SIRPA FCRL5 LRIT1	1.44e-07	421	77	12	IPR003599
Domain	ig	HSPG2 NPTN HMCN1 NCAM1 SIGLEC1 FCRL5 LRIT1	1.33e-05	190	77	7	PF00047
Domain	Immunoglobulin	HSPG2 NPTN HMCN1 NCAM1 SIGLEC1 FCRL5 LRIT1	1.33e-05	190	77	7	IPR013151
Domain	SEA	HSPG2 MUC17 MUC3A	2.37e-05	14	77	3	SM00200
Domain	Cys-rich_flank_reg_C	SLIT2 LRFN2 LRIG1 TLR7 LRIT1	3.49e-05	90	77	5	IPR000483
Domain	LRRCT	SLIT2 LRFN2 LRIG1 TLR7 LRIT1	3.49e-05	90	77	5	SM00082
Domain	LRRNT	SLIT2 LRFN2 LRIG1 TLR7 LRIT1	5.26e-05	98	77	5	IPR000372
Domain	LRRNT	SLIT2 LRFN2 LRIG1 TLR7 LRIT1	5.26e-05	98	77	5	SM00013
Domain	fn3	COL12A1 LRFN2 PTPRF NCAM1 LRIT1 EPHA4	5.53e-05	162	77	6	PF00041
Domain	Neural_cell_adh	HMCN1 NCAM1	1.00e-04	4	77	2	IPR009138
Domain	SEA	HSPG2 MUC17 MUC3A	1.12e-04	23	77	3	PS50024
Domain	SEA_dom	HSPG2 MUC17 MUC3A	1.12e-04	23	77	3	IPR000082
Domain	FN3	COL12A1 LRFN2 PTPRF NCAM1 LRIT1 EPHA4	1.15e-04	185	77	6	SM00060
Domain	FN3	COL12A1 LRFN2 PTPRF NCAM1 LRIT1 EPHA4	1.72e-04	199	77	6	PS50853
Domain	FN3_dom	COL12A1 LRFN2 PTPRF NCAM1 LRIT1 EPHA4	2.24e-04	209	77	6	IPR003961
Domain	LRRCT	SLIT2 LRIG1 TLR7	3.07e-04	32	77	3	PF01463
Domain	MHC_II_b_N	HLA-DQB1 HLA-DQB2	4.62e-04	8	77	2	PD000328
Domain	MHC_II_beta	HLA-DQB1 HLA-DQB2	5.93e-04	9	77	2	PF00969
Domain	MHC_II_b_N	HLA-DQB1 HLA-DQB2	5.93e-04	9	77	2	IPR000353
Domain	MHC_II_beta	HLA-DQB1 HLA-DQB2	5.93e-04	9	77	2	SM00921
Domain	-	SLIT2 HSPG2 COL12A1 ADGRG4	6.40e-04	95	77	4	2.60.120.200
Domain	LRR_8	SLIT2 LRFN2 LRIG1 TLR7 LRIT1	7.04e-04	171	77	5	PF13855
Domain	Leu-rich_rpt_typical-subtyp	SLIT2 LRFN2 LRIG1 TLR7 LRIT1	8.23e-04	177	77	5	IPR003591
Domain	LRR_TYP	SLIT2 LRFN2 LRIG1 TLR7 LRIT1	8.23e-04	177	77	5	SM00369
Domain	Laminin_G_1	SLIT2 HSPG2	9.01e-04	11	77	2	PF00054
Domain	Ig_V-set	HAVCR1 HSPG2 HMCN1 SIGLEC1 SIRPA	1.39e-03	199	77	5	IPR013106
Domain	C1-set	HLA-DQB1 HLA-DQB2 SIRPA	1.44e-03	54	77	3	PF07654
Domain	LRR	SLIT2 LRFN2 LRIG1 TLR7 LRIT1	1.45e-03	201	77	5	PS51450
Domain	MHC_II_a/b_N	HLA-DQB1 HLA-DQB2	1.48e-03	14	77	2	IPR014745
Domain	PB1	PARD6G NBR1	1.48e-03	14	77	2	SM00666
Domain	PB1	PARD6G NBR1	1.48e-03	14	77	2	PF00564
Domain	-	HLA-DQB1 HLA-DQB2	1.48e-03	14	77	2	3.10.320.10
Domain	PB1	PARD6G NBR1	1.48e-03	14	77	2	PS51745
Domain	PB1_dom	PARD6G NBR1	1.48e-03	14	77	2	IPR000270
Domain	IGc1	HLA-DQB1 HLA-DQB2 SIRPA	1.60e-03	56	77	3	SM00407
Domain	Laminin_G	SLIT2 HSPG2 COL12A1	1.77e-03	58	77	3	IPR001791
Domain	Ig_C1-set	HLA-DQB1 HLA-DQB2 SIRPA	1.77e-03	58	77	3	IPR003597
Domain	Ig/MHC_CS	HAVCR1 HLA-DQB1 HLA-DQB2	1.77e-03	58	77	3	IPR003006
Domain	IG_MHC	HAVCR1 HLA-DQB1 HLA-DQB2	1.95e-03	60	77	3	PS00290
Domain	LRR_1	SLIT2 LRFN2 LRIG1 TLR7 LRIT1	2.11e-03	219	77	5	PF00560
Domain	EGF_3	SLIT2 HSPG2 HMCN1 MUC17 MUC3A	2.86e-03	235	77	5	PS50026
Domain	EGF	SLIT2 HSPG2 HMCN1 MUC17 MUC3A	2.86e-03	235	77	5	SM00181
Domain	Ig_2	HSPG2 SIGLEC1 FCRL5	3.41e-03	73	77	3	PF13895
Domain	EGF-like_dom	SLIT2 HSPG2 HMCN1 MUC17 MUC3A	3.66e-03	249	77	5	IPR000742
Domain	SEA	HSPG2 MUC17	3.67e-03	22	77	2	PF01390
Domain	IGv	HSPG2 HMCN1 SIRPA	3.68e-03	75	77	3	SM00406
Domain	EGF_1	SLIT2 HSPG2 HMCN1 MUC17 MUC3A	4.05e-03	255	77	5	PS00022
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	EPRS1 NCOA6 PPP2R1A GTF3C1 ANK3 RPS3 ARID2 GEMIN5 TAF4 MIDEAS PRPF40A	4.71e-08	549	79	11	38280479
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	NPTN LRFN2 PTPRF HMCN1 LRIG1 SIGLEC1 LRIT1	9.14e-08	162	79	7	25826454
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	HSPD1 EPRS1 HSPG2 NPTN CLU RPS3 PIGS SPTLC1 GEMIN5 TAF4 TMEM231	1.43e-07	613	79	11	22268729
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NPTN PPP2R1A ARHGAP32 ANK3 CLU CTCF DCHS1 NCAM1 TSC1 SIRPA TAF4 RTN1 EPHA4	2.53e-07	963	79	13	28671696
Pubmed	Functional proteomics mapping of a human signaling pathway.	ZNF512B HIPK3 HSPG2 NCOA6 PPP2R1A PTPRF ANK3 HIPK1 PRPF40A SON	9.37e-07	591	79	10	15231748
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	ZNF512B HSPD1 EPRS1 NCOA6 CTCF RPS3 ARID2 NOL6 TAF4 MIDEAS PRPF40A SON	1.60e-06	954	79	12	36373674
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	HSPD1 EPRS1 PPP2R1A GTF3C1 CTCF RPS3 GEMIN5 TAF4 MIDEAS PRPF40A	2.35e-06	655	79	10	35819319
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	HSPD1 NPTN IPO8 PTPRF CTCF RPS3 PIGS NOL6 SPTLC1 GEMIN5 NCAM1 SIRPA PRPF40A	3.02e-06	1203	79	13	29180619
Pubmed	Human transcription factor protein interaction networks.	ZNF512B HSPD1 HSPG2 NCOA6 PPP2R1A ARHGAP32 TSHZ3 GTF3C1 PITRM1 CTCF ARID2 TAF4 MIDEAS PRPF40A	3.74e-06	1429	79	14	35140242
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	HSPD1 EPRS1 NPTN PPP2R1A ARHGAP32 ANK3 LRIG1 CLU RPS3 GEMIN5 NCAM1 TSC1 RTN1 PRPF40A	3.80e-06	1431	79	14	37142655
Pubmed	The tumour-suppressive function of CLU is explained by its localisation and interaction with HSP60.	HSPD1 CLU	5.09e-06	2	79	2	22012253
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ZNF512B HSPD1 EPRS1 NCOA6 PPP2R1A MYPOP GTF3C1 ZBED4 CTCF TAF4 MIDEAS PRPF40A SON	6.64e-06	1294	79	13	30804502
Pubmed	PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.	HAVCR1 LRFN2 NCAM1 LRIT1 EPHA4	7.30e-06	117	79	5	17145500
Pubmed	In vivo visualization and molecular targeting of the cardiac conduction system.	SLIT2 NPTN EPHA4	7.50e-06	17	79	3	35951416
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF512B SLIT2 CLU CCNB3 CTCF ARID2 SPTLC1 SIGLEC1 TAF4 PRPF40A SLC40A1 SON	7.94e-06	1116	79	12	31753913
Pubmed	MORC2B is essential for meiotic progression and fertility.	CCNB3 PIWIL1 CFAP65	8.98e-06	18	79	3	29329290
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	TDRD7 KPNA5 HAVCR1 HSPG2 ARHGAP32 IPO8 NIF3L1 PRPF40A NBR1	9.97e-06	608	79	9	16713569
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	HSPD1 EPRS1 PPP2R1A GTF3C1 RPS3 ARID2 GEMIN5	1.09e-05	332	79	7	32786267
Pubmed	Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.	MUC17 MUC3A	1.53e-05	3	79	2	10512748
Pubmed	Update on the Regulation of HIPK1, HIPK2 and HIPK3 Protein Kinases by microRNAs.	HIPK3 HIPK1	1.53e-05	3	79	2	29793420
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	ZNF512B HSPD1 SLIT2 EPRS1 PPP2R1A GTF3C1 PTPRF RPS3 NOL6 PRPF40A SON	1.98e-05	1024	79	11	24711643
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	NPTN ARHGAP32 PTPRF ANK3 SPTLC1 PARD6G SIRPA	2.47e-05	377	79	7	38117590
Pubmed	Class II genes of the human major histocompatibility complex. Comparisons of the DQ and DX alpha and beta genes.	HLA-DQB1 HLA-DQB2	3.05e-05	4	79	2	3036828
Pubmed	Effect of tyrosine autophosphorylation on catalytic activity and subcellular localisation of homeodomain-interacting protein kinases (HIPK).	HIPK3 HIPK1	3.05e-05	4	79	2	25630557
Pubmed	Tim-1-Fc suppresses chronic cardiac allograft rejection and vasculopathy by reducing IL-17 production.	HAVCR1 HLA-DQB2	3.05e-05	4	79	2	24551271
Pubmed	Fragile TIM-4-expressing tissue resident macrophages are migratory and immunoregulatory.	HLA-DQB2 SIGLEC1	3.05e-05	4	79	2	24983317
Pubmed	Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation.	HIPK3 HIPK1	3.05e-05	4	79	2	34785661
Pubmed	A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.	HLA-DQB1 HLA-DQB2	3.05e-05	4	79	2	21750111
Pubmed	The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model.	HAVCR1 HLA-DQB2	3.05e-05	4	79	2	18172549
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ZNF512B HSPD1 EPRS1 CTCF ARID2 GEMIN5 TSC1 RTN1 PRPF40A SON	5.02e-05	934	79	10	33916271
Pubmed	CD169+ macrophages orchestrate plasmacytoid dendritic cell arrest and retention for optimal priming in the bone marrow of malaria-infected mice.	TLR7 SIGLEC1	5.07e-05	5	79	2	36278864
Pubmed	ICAM1+ neutrophils promote chronic inflammation via ASPRV1 in B cell-dependent autoimmune encephalomyelitis.	HLA-DQB2 IL36G	5.07e-05	5	79	2	29212956
Pubmed	Molecular mechanism and cellular function of MHCII ubiquitination.	HLA-DQB1 HLA-DQB2	5.07e-05	5	79	2	26085212
Pubmed	Cross-reactivity of anti-programmed death ligand 2 polyclonal antibody in mouse tissues.	HMCN1 NCAM1	5.07e-05	5	79	2	23090063
Pubmed	DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.	HSPD1 EPRS1 PPP2R1A RPS3 GEMIN5	5.08e-05	175	79	5	25756610
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	SLIT2 EPRS1 NPTN PPP2R1A PTPRF LRIG1 PIGS SPTLC1 RTN1 NBR1	5.39e-05	942	79	10	31073040
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	PPP2R1A GTF3C1 ZBED4 CTCF RPS3 NOL6 TAF4 SON	5.46e-05	583	79	8	29844126
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	NCOA6 ARHGAP32 TSHZ3 ANK3 ARID2 SH3D21 SON	5.67e-05	430	79	7	35044719
Pubmed	Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo.	LRFN2 LRIG1 LRIT1	6.42e-05	34	79	3	18848646
Pubmed	The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity.	SMPDL3A TLR7	7.60e-05	6	79	2	26095358
Pubmed	Multimodal control of dendritic cell functions by nociceptors.	HLA-DQB2 TLR7	7.60e-05	6	79	2	36996219
Pubmed	Involvement of the Hipk family in regulation of eyeball size, lens formation and retinal morphogenesis.	HIPK3 HIPK1	7.60e-05	6	79	2	20579985
Pubmed	Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors.	HIPK3 HIPK1	7.60e-05	6	79	2	9748262
Pubmed	Alveolar macrophages and lung dendritic cells sense RNA and drive mucosal IgA responses.	HLA-DQB2 TLR7	7.60e-05	6	79	2	19710454
Pubmed	Polysialylated NCAM and ephrinA/EphA regulate synaptic development of GABAergic interneurons in prefrontal cortex.	NCAM1 EPHA4	7.60e-05	6	79	2	22275477
Pubmed	Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity.	HIPK3 HIPK1	7.60e-05	6	79	2	12529400
Pubmed	STING-Licensed Macrophages Prime Type I IFN Production by Plasmacytoid Dendritic Cells in the Bone Marrow during Severe Plasmodium yoelii Malaria.	TLR7 SIGLEC1	7.60e-05	6	79	2	27792766
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	HSPD1 EPRS1 PPP2R1A IPO8 GTF3C1 PITRM1 RPS3 NOL6 SPTLC1 GEMIN5 PRPF40A NBR1	8.63e-05	1425	79	12	30948266
Pubmed	Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP.	HIPK3 PTPRF HIPK1	8.99e-05	38	79	3	28680062
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	HSPD1 GARIN5B EPRS1 MYPOP GTF3C1 ZBED4 NOL6 CFAP74 TSC1 TAF4 SH3D21 EPHA4	9.65e-05	1442	79	12	35575683
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	HSPD1 SLIT2 EPRS1 HSPG2 NPTN LRIG1 PITRM1 RPS3 PIGS SPTLC1 TMEM231 PRPF40A	1.02e-04	1451	79	12	30550785
Pubmed	New genetic associations detected in a host response study to hepatitis B vaccine.	HAVCR1 PPP2R1A HLA-DQB1 HLA-DQB2 TLR7 SIGLEC1 FCRL5 IL36G LRIT1	1.05e-04	824	79	9	20237496
Pubmed	TLR7 Controls VSV Replication in CD169+ SCS Macrophages and Associated Viral Neuroinvasion.	TLR7 SIGLEC1	1.06e-04	7	79	2	30930901
Pubmed	FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation.	HIPK3 HIPK1	1.06e-04	7	79	2	11034606
Pubmed	Disruption of anterior segment development by TGF-beta1 overexpression in the eyes of transgenic mice.	HSPG2 NCAM1	1.06e-04	7	79	2	12242711
Pubmed	TLR7-dependent eosinophil degranulation links psoriatic skin inflammation to small intestinal inflammatory changes in mice.	TLR7 SIRPA	1.06e-04	7	79	2	38689088
Pubmed	Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.	HSPD1 ANK3 PITRM1 RPS3 MYOZ2 SON	1.10e-04	331	79	6	29199018
Pubmed	A human MAP kinase interactome.	HSPD1 HIPK3 ARHGAP32 ANK3 HIPK1 ARID2 MIDEAS	1.21e-04	486	79	7	20936779
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	HSPD1 KPNA5 HSPG2 PPP2R1A ANK3 HMCN1 CLU RPS3 IL36G	1.26e-04	844	79	9	25963833
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	ZNF512B EPRS1 GTF3C1 CTCF RPS3 ARID2 NOL6 PRPF40A SON	1.30e-04	847	79	9	35850772
Pubmed	Extracellular Hsp90α and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1.	HSPG2 COL12A1 CLU	1.40e-04	44	79	3	31273033
Pubmed	Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions.	ADGRF4 ADGRG4	1.41e-04	8	79	2	12435584
Pubmed	Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases.	LRIG1 NCAM1	1.41e-04	8	79	2	26651291
Pubmed	Loss of short dystrophin isoform Dp71 in olfactory ensheathing cells causes vomeronasal nerve defasciculation in mouse olfactory system.	HSPG2 NCAM1	1.41e-04	8	79	2	18586242
Pubmed	Interaction network of human early embryonic transcription factors.	ZNF512B NCOA6 TSHZ3 ARID2 TAF4 MIDEAS	1.51e-04	351	79	6	38297188
Pubmed	Gene essentiality and synthetic lethality in haploid human cells.	EPRS1 PPP2R1A CTCF SPTLC1 PRPF40A	1.80e-04	229	79	5	26472760
Pubmed	Dynamic expression patterns of ECM molecules in the developing mouse olfactory pathway.	HSPG2 NCAM1	1.82e-04	9	79	2	18570250
Pubmed	Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.	HSPG2 COL12A1 CLU	2.05e-04	50	79	3	23658023
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	HSPD1 EPRS1 PPP2R1A IPO8 RPS3 NOL6 PRPF40A SON	2.20e-04	714	79	8	28302793
Pubmed	Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members.	TDRD7 PIWIL1	2.27e-04	10	79	2	19584108
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	HSPD1 EPRS1 PPP2R1A GTF3C1 RPS3 NOL6 GEMIN5 TSC1 MIDEAS IL36G SON	2.37e-04	1353	79	11	29467282
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	SLIT2 HSPG2 COL12A1 CLU SMPDL3A	2.60e-04	248	79	5	24006456
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	HSPD1 EPRS1 PPP2R1A ARHGAP32 IPO8 RPS3 TAF4	2.61e-04	551	79	7	34728620
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	HIPK3 SLIT2 ARHGAP32 IPO8 CRYBG1 MUC3A SH3D21	2.64e-04	552	79	7	10737800
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	ARHGAP32 ANK3 CLU NCAM1 SIRPA	2.74e-04	251	79	5	27507650
Pubmed	Proteome identification of binding-partners interacting with cell polarity protein Par3 in Jurkat cells.	HSPD1 RPS3	2.76e-04	11	79	2	18685789
Pubmed	CTLA-4 blockade induces a microglia-Th1 cell partnership that stimulates microglia phagocytosis and anti-tumor function in glioblastoma.	HLA-DQB2 SIGLEC1	2.76e-04	11	79	2	37572655
Pubmed	Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.	TLR7 SIGLEC1	2.76e-04	11	79	2	29249358
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	EPRS1 PPP2R1A GTF3C1 CTCF ARID2 MIDEAS	2.82e-04	394	79	6	27248496
Pubmed	Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.	HSPD1 EPRS1 PPP2R1A IPO8 RPS3	3.00e-04	256	79	5	32698014
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	HSPG2 PTPRF CLU NCAM1 SIRPA	3.06e-04	257	79	5	16335952
Pubmed	The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis.	HSPD1 HSPG2 TAGAP RPS3	3.07e-04	141	79	4	32322062
Pubmed	Defining the membrane proteome of NK cells.	HSPD1 EPRS1 GTF3C1 RPS3 HLA-DQB1 PIGS GEMIN5 NCAM1 PRPF40A NBR1	3.09e-04	1168	79	10	19946888
Pubmed	LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.	HSPD1 EPRS1 PPP2R1A HMCN1	3.16e-04	142	79	4	30809309
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	ZNF512B HSPD1 IPO8 PTPRF NOL6 SPTLC1 DCHS1 NIF3L1	3.16e-04	754	79	8	35906200
Pubmed	Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.	HSPD1 NPTN PPP2R1A ANK3 NCAM1 RTN1	3.18e-04	403	79	6	30562941
Pubmed	USP7 controls NGN3 stability and pancreatic endocrine lineage development.	HSPD1 GTF3C1 RPS3	3.18e-04	58	79	3	37117185
Pubmed	Zinc-finger gene Fez in the olfactory sensory neurons regulates development of the olfactory bulb non-cell-autonomously.	SLIT2 NCAM1	3.31e-04	12	79	2	16540508
Pubmed	HIV-1 Nef impairs MHC class II antigen presentation and surface expression.	HLA-DQB1 HLA-DQB2	3.31e-04	12	79	2	11593029
Pubmed	Multiple influences on the migration of precerebellar neurons in the caudal medulla.	NCAM1 EPHA4	3.31e-04	12	79	2	11807023
Pubmed	Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.	HLA-DQB1 HLA-DQB2	3.31e-04	12	79	2	12970439
Pubmed	Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals.	HIPK3 HIPK1	3.31e-04	12	79	2	16537918
Pubmed	Regulation of neuronal migration by Dchs1-Fat4 planar cell polarity.	DCHS1 EPHA4	3.31e-04	12	79	2	24998526
Pubmed	Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr.	KPNA5 CCNB3	3.31e-04	12	79	2	7494303
Pubmed	The Opitz syndrome gene product MID1 assembles a microtubule-associated ribonucleoprotein complex.	PPP2R1A RPS3	3.31e-04	12	79	2	18172692
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	HSPD1 PPP2R1A PTPRF CLU HIPK1	3.34e-04	262	79	5	36880596
Pubmed	Establishment of fetomaternal tolerance through glycan-mediated B cell suppression.	HLA-DQB2 SIGLEC1	3.91e-04	13	79	2	35236989
Pubmed	A selective defect in the glial wedge as part of the neuroepithelium disruption in hydrocephalus development in the mouse hyh model is associated with complete corpus callosum dysgenesis.	SLIT2 NCAM1	3.91e-04	13	79	2	38450283
Pubmed	Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway.	TLR7 SIGLEC1	4.55e-04	14	79	2	32515732
Pubmed	Dystroglycan organizes axon guidance cue localization and axonal pathfinding.	SLIT2 HSPG2	4.55e-04	14	79	2	23217742
Interaction	FEV interactions	ZNF512B NCOA6 GTF3C1 CTCF ARID2 TAF4 MIDEAS	1.26e-05	203	77	7	int:FEV
Interaction	FBXO6 interactions	HSPD1 EPRS1 HSPG2 NPTN COL12A1 CLU RPS3 PIGS SPTLC1 GEMIN5 TAF4 TMEM231	1.65e-05	717	77	12	int:FBXO6
Cytoband	5q33.2	HAVCR1 GEMIN5	3.45e-04	16	79	2	5q33.2
Cytoband	14q23.1	RTN1 ARMH4	3.01e-03	47	79	2	14q23.1
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HSPG2 NPTN LRFN2 PTPRF HMCN1 LRIG1 NCAM1 SIGLEC1 LRIT1	1.06e-09	161	54	9	593
GeneFamily	Fibronectin type III domain containing	COL12A1 LRFN2 PTPRF NCAM1 LRIT1 EPHA4	7.95e-06	160	54	6	555
GeneFamily	C1-set domain containing	HLA-DQB1 HLA-DQB2 SIRPA	2.66e-04	42	54	3	591
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP32 TAGAP ARHGAP28	4.47e-04	50	54	3	721
GeneFamily	Armadillo repeat containing\|Importins	KPNA5 IPO8	1.30e-03	18	54	2	596
GeneFamily	CD molecules\|Mucins	MUC17 MUC3A	1.77e-03	21	54	2	648
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	HAVCR1 NCAM1 SIGLEC1 SIRPA FCRL5	6.31e-03	394	54	5	471
GeneFamily	Histocompatibility complex\|C1-set domain containing	HLA-DQB1 HLA-DQB2	7.64e-03	44	54	2	588
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HAVCR1 SMPDL3A TLR7 SIGLEC1 SIRPA SLC40A1 ARMH4	2.15e-08	169	79	7	0f5e737b265ba333275a0cd289dab029a1542075
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HAVCR1 SMPDL3A SIGLEC1 SIRPA SLC40A1 ARMH4	5.69e-07	169	79	6	aec1b4c7e973a31c53aaea47c2c05d24ce16aa4f
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SLIT2 HMCN1 SMPDL3A NCAM1 ARHGAP28 SLC40A1	1.09e-06	189	79	6	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PTPRF ANK3 LRIG1 CFAP74 TMEM231 CFAP65	1.24e-06	193	79	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-DQB1 TLR7 SIGLEC1 SIRPA RTN1 SLC40A1	1.27e-06	194	79	6	ad72be9f6871b334e1f477d868c15e7792fadea5
ToppCell	10x5'-GI_small-bowel-Myeloid_Mac-Intestinal_macrophages\|GI_small-bowel / Manually curated celltypes from each tissue	SMPDL3A HLA-DQB1 TLR7 SIGLEC1 SIRPA RTN1	1.35e-06	196	79	6	075e5746fa5cb121115a1d51b823c0fbf8d54305
ToppCell	10x5'-GI_small-bowel-Myeloid_Mac\|GI_small-bowel / Manually curated celltypes from each tissue	SMPDL3A HLA-DQB1 TLR7 SIGLEC1 SIRPA SLC40A1	1.43e-06	198	79	6	748db69d3c9774e44c0cc425d937d18b83af8312
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD7 MYPOP IL36G SLC40A1 CFAP65	3.96e-06	133	79	5	f6e9a1301a3379847b215303a9b0c028841e2cc0
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD7 MYPOP IL36G SLC40A1 CFAP65	3.96e-06	133	79	5	292ecfcadbaf15e0d34a3ab9bf511ab1065888bd
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS3 SLC38A4 SPTLC1 FCRL5 LRIT1	8.88e-06	157	79	5	14c4c61790eba6a388679e6d5011424d56cf3b5a
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	PTPRF HIPK1 SLFNL1 SON C16orf46	1.16e-05	166	79	5	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells\|World / Stress and Cell class	SLIT2 NPTN ANK3 CLU NCAM1	1.54e-05	176	79	5	ce2c32b5ce0da848eb4da35ce4d215cdf74d9113
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SLIT2 COL12A1 CLU PARD6G NCAM1	1.86e-05	183	79	5	27a57cd8ea924420e182f3d72f5b29b00dea8fa0
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 SLC38A4 PARD6G GEMIN5 SIRPA	1.86e-05	183	79	5	919c9861073d12fd12aecd7469b1478b13838c43
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	TSHZ3 COL12A1 HMCN1 SLC40A1 ARMH4	2.07e-05	187	79	5	a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SLIT2 HSPG2 COL12A1 CLU NCAM1	2.12e-05	188	79	5	de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCell	facs-MAT\|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLIT2 PTPRF CLU RPS3 ARMH4	2.29e-05	191	79	5	b4fba92f9bd1354a07fedfca7304a3757e6d5beb
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-Macrophages\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-DQB1 TLR7 SIGLEC1 SIRPA SLC40A1	2.29e-05	191	79	5	94c7da03e5264f4d73bb507ce339a935d90279a0
ToppCell	Fetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HLA-DQB1 SIGLEC1 SIRPA RTN1 SLC40A1	2.29e-05	191	79	5	24d75b7e1d6fb9d24aa7844f584ee888a449841f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRF ANK3 CLU SLC38A4 CRYBG1	2.46e-05	194	79	5	be869e186386d03ebb670971dd24fa656b4b0edf
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPTN TAGAP TLR7 SIRPA SLC40A1	2.46e-05	194	79	5	2224c7c943cfd5c1a329dfcf19d6e5ef8c49d85d
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPTN TAGAP TLR7 SIRPA SLC40A1	2.46e-05	194	79	5	50c5fc349533281a426bc7227a8ea9eca8d11985
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP74 TMEM231 ARMH4 C16orf46 CFAP65	2.46e-05	194	79	5	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SLIT2 TSHZ3 SMPDL3A ARHGAP28 SLC40A1	2.46e-05	194	79	5	99577a5a631e607b5abe7a1b0d8d6a5eabe50196
ToppCell	facs-Brain_Myeloid-Cortex-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPTN TAGAP TLR7 SIRPA SLC40A1	2.46e-05	194	79	5	1662b110f84584e75150df0ac970e7df82f26e7e
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPTN TAGAP TLR7 SIRPA SLC40A1	2.46e-05	194	79	5	b31d6361fa939a92a4a3dc63c209ecd3eb514e6a
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SLIT2 TSHZ3 SMPDL3A ARHGAP28 SLC40A1	2.52e-05	195	79	5	70387a62f121f8c374dba1aca9ab65cfed6a0b10
ToppCell	PCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor2_(3)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	HLA-DQB1 TLR7 SIGLEC1 SIRPA RTN1	2.52e-05	195	79	5	799992721369357484300fe218aff075154c3148
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor2_(3)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TAGAP TLR7 SIGLEC1 SIRPA RTN1	2.52e-05	195	79	5	e8fb552f9ab77b656c27abc66af523b56cd9f9ad
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 CLU PARD6G NCAM1 SIRPA	2.52e-05	195	79	5	cad21edd90bf3e2fefdf5773a59cb1a664a69ddd
ToppCell	facs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 CLU PARD6G NCAM1 SIRPA	2.52e-05	195	79	5	7e0ef92059ff34e368d2324815f49b50e3ca7332
ToppCell	facs-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 NPTN PTPRF ANK3 SLC38A4	2.52e-05	195	79	5	c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_proliferating_myeloid_(8)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TAGAP HLA-DQB1 TLR7 SIRPA RTN1	2.59e-05	196	79	5	3fd5567ea14193181929134c377e8a38fb4f47fd
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TAGAP TLR7 SIGLEC1 SIRPA RTN1	2.59e-05	196	79	5	ce3709adbde7559b40c964888935914f66003247
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPD1 TAGAP HLA-DQB1 SIGLEC1 SIRPA	2.59e-05	196	79	5	5fe6534af65d43eeacd4b031310242b4f706008b
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Dendritic_cell-DC_2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HLA-DQB1 HLA-DQB2 TLR7 SIGLEC1 RTN1	2.59e-05	196	79	5	8862964090f9a679a548103bfbb12e91295aae62
ToppCell	(3)_Macrophage_MARCOneg\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CLU HLA-DQB2 TLR7 SIGLEC1 SLC40A1	2.65e-05	197	79	5	b0ee2ce1179b60b4542559acb300a34295277dbc
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Dendritic_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HLA-DQB1 HLA-DQB2 TLR7 SIGLEC1 RTN1	2.65e-05	197	79	5	e0fc098bfb5a8b7824ae339f3adda30f78360d0b
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	SLIT2 ANK3 HMCN1 ARHGAP28 SLC40A1	2.65e-05	197	79	5	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SLIT2 COL12A1 CLU PARD6G NCAM1	2.72e-05	198	79	5	1f956e369e00d37835095a001db4b62a79014532
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SLIT2 COL12A1 CLU PARD6G NCAM1	2.72e-05	198	79	5	dc6fbad0ecdd057189f71afcdb6aca25207314a3
ToppCell	11.5-Airway-Mesenchymal-Mesenchyme_RSPO2+\|Airway / Age, Tissue, Lineage and Cell class	SLIT2 RPS3 SMPDL3A ARHGAP28 SLC40A1	2.72e-05	198	79	5	23783572c22c24d9fb8e14dc1f3852d2094157df
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SLIT2 COL12A1 CLU PARD6G NCAM1	2.72e-05	198	79	5	6a539d3b47bd2d4a7ad5c67cad23facffc0ac45f
ToppCell	Parenchyma_COVID-19\|World / Sample group, Lineage and Cell type	COL12A1 SMPDL3A ARHGAP28 FCRL5 SLC40A1	2.72e-05	198	79	5	45ab554e6d0399b3182f089a25b2adf96de1144b
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SLIT2 COL12A1 CLU PARD6G NCAM1	2.78e-05	199	79	5	7b1b3b108d817fb3b50a710c3146b30bcf9c2f6b
ToppCell	3'_v3-GI_small-bowel-Myeloid_Mac\|GI_small-bowel / Manually curated celltypes from each tissue	SMPDL3A HLA-DQB1 SIGLEC1 SIRPA SLC40A1	2.78e-05	199	79	5	8990a3d69e24cb3aaba9d6def3d0be9ee973436d
ToppCell	3'_v3-GI_small-bowel-Myeloid_Mac-Intestinal_macrophages\|GI_small-bowel / Manually curated celltypes from each tissue	SMPDL3A HLA-DQB1 SIGLEC1 SIRPA SLC40A1	2.78e-05	199	79	5	96070b5ffcbab4952970f43b536969ddd2ca5d14
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-DQB1 HLA-DQB2 SIGLEC1 RTN1 SLC40A1	2.78e-05	199	79	5	c684530d4d8073337379c2a24e5e54297fb13691
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-B-B_cell-B_naive\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TAGAP HLA-DQB1 TLR7 FCRL5 SH3D21	2.78e-05	199	79	5	8bc07beace200ae2ad41e932b72fdcc7ff08b812
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SLIT2 COL12A1 CLU PARD6G NCAM1	2.78e-05	199	79	5	f2ad641f36c577ff7019e88ad6b73ed7e46d8c74
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SLIT2 COL12A1 CLU PARD6G NCAM1	2.85e-05	200	79	5	780d47f8eff630020dfae32218de495a7e9dbad6
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SLIT2 COL12A1 CLU PARD6G NCAM1	2.85e-05	200	79	5	28dd127787a57276253548d1f030814b1af64481
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TAGAP HLA-DQB1 HLA-DQB2 TLR7 RTN1	2.85e-05	200	79	5	27f498bcd706d0751091662996795b5270e46f14
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	HMCN1 CCNB3 SLC40A1 SH3D21	1.19e-04	142	79	4	5ef69032ed7dc5f2244b84e8c6662290bf59a34b
ToppCell	Adult-Immune-dendritic_cell-D231\|Adult / Lineage, Cell type, age group and donor	HLA-DQB1 HLA-DQB2 MYOZ2 NCAM1	1.36e-04	147	79	4	7cc4f74dd7a86247db8dc049ed7eadeb53825a96
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_and_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	COL12A1 HMCN1 ARHGAP28 ARMH4	1.43e-04	149	79	4	3904f8ce9078de238600ceceee0116af52256a1c
ToppCell	mild_COVID-19_(asymptomatic)-NK_CD56bright\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	HSPG2 NCAM1 EPHA4 C16orf46	1.51e-04	151	79	4	2470162f4b56bc505db166a6eb0fa54847759df8
ToppCell	NS-moderate-d_0-4-Myeloid-Monocyte-derived_DC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	HLA-DQB1 SIRPA RTN1 SLC40A1	1.54e-04	152	79	4	ce944f7c1444fd0cb793db183b96818e37342b24
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Neuronal\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	PPP2R1A ANK3 RTN1	1.58e-04	59	79	3	74590437b1d9a2a8fe56d79b2e66803528b81298
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_memory_T_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PTPRF HIPK1 CRYBG1 LRIT1	1.58e-04	153	79	4	64d0f37d7af9b76234f683379e3689771f71fe70
ToppCell	mild_COVID-19_(asymptomatic)-NK_CD56bright\|World / disease group, cell group and cell class (v2)	HSPG2 NCAM1 EPHA4 C16orf46	1.58e-04	153	79	4	aff5c8ab1fb4ebc324cec02cf562b7484bb10db8
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PARD6G ARHGAP28 SIRPA ARMH4	1.67e-04	155	79	4	90e629681a72baacc7981b82883866a487638dbc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PARD6G ARHGAP28 SIRPA ARMH4	1.67e-04	155	79	4	e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PARD6G ARHGAP28 SIRPA ARMH4	1.67e-04	155	79	4	5a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCell	facs-GAT-Fat-24m\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS3 SPTLC1 FCRL5 RTN1	1.75e-04	157	79	4	c4a0b6c95d353691fd2846002ce4bc7c2b0edd1c
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_2\|368C / Donor, Lineage, Cell class and subclass (all cells)	CCNB3 HLA-DQB1 HLA-DQB2 SH3D21	1.88e-04	160	79	4	ac3f56f8ab8efd11c4b4868a828db05c23ac762f
ToppCell	facs-Spleen-nan-3m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP28 SIRPA RTN1 SLC40A1	1.93e-04	161	79	4	45591addc765760db6029ac19e80573373d1d917
ToppCell	facs-Spleen-nan-3m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP28 SIRPA RTN1 SLC40A1	1.93e-04	161	79	4	8741b91a62c9a8ce377ef6533d323b65beb93c63
ToppCell	facs-Spleen-nan-3m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP28 SIRPA RTN1 SLC40A1	1.93e-04	161	79	4	9cf1dcf0e7ca9e35c46c094a6b78f98d1f6b9276
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC38A4 NOL6 NIF3L1 ARMH4	2.02e-04	163	79	4	360cd65decda24853124f33a174f5224d7f3ce23
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC38A4 NOL6 NIF3L1 ARMH4	2.02e-04	163	79	4	b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCell	Basal_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	TSHZ3 CLU PIWIL1 PARD6G	2.02e-04	163	79	4	679e25e5548d157d49a73057a3b5617dccda260f
ToppCell	facs-Skin-nan-24m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 RPS3 SPTLC1 FCRL5	2.07e-04	164	79	4	7a65c7a6dbe5fb9067f83efafbb7ec8206d79325
ToppCell	facs-Heart-LV-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOZ2 MIDEAS IL36G SLC40A1	2.12e-04	165	79	4	84eca6a0f5e996b6955ae79fa102af239098fe8f
ToppCell	facs-Heart-LV-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOZ2 MIDEAS IL36G SLC40A1	2.12e-04	165	79	4	af59a095ecc6758abc13d763c00e44447c488167
ToppCell	mild-Lymphocytic-B_cells_2\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	HLA-DQB1 HLA-DQB2 TLR7 FCRL5	2.21e-04	167	79	4	0811f7559c2a7151693771e52e14af3978997118
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HLA-DQB1 HLA-DQB2 SIRPA RTN1	2.27e-04	168	79	4	eba865465feb0f42055bb8f98946050eeb03d177
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMPDL3A SIGLEC1 SLC40A1 ARMH4	2.32e-04	169	79	4	44d841fd997a6f26104f16cd00223ecce8352f43
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAM1 SIRPA IL36G SLC40A1	2.32e-04	169	79	4	1000eaf5158596b4898bedcc802b31db76b05a48
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAM1 SIRPA IL36G SLC40A1	2.32e-04	169	79	4	83b854fa8fd9017df8f9207d9ced260eee98e8c1
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PARD6G ARHGAP28 SIRPA ARMH4	2.37e-04	170	79	4	60bbd738c12e64e483485586c30057304884f5a6
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	MYOZ2 NCAM1 SIGLEC1 RTN1	2.37e-04	170	79	4	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	Immune_cells-Dendritic_cells\|World / Lineage and Cell class	HAVCR1 TAGAP TLR7 SIRPA	2.37e-04	170	79	4	094dc211d80c89ecb1010855f1fe6eeb71bf0e20
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLIT2 HSPG2 ARHGAP32 PARD6G	2.37e-04	170	79	4	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	droplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HAVCR1 ARHGAP32 PTPRF TLR7	2.42e-04	171	79	4	4e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCell	droplet-Thymus-nan-3m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP28 SIRPA RTN1 SLC40A1	2.42e-04	171	79	4	25493a4a7b636920e2cfd984542cc500709c9dcf
ToppCell	droplet-Thymus-nan-3m-Myeloid-professional_antigen_presenting_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP28 SIRPA RTN1 SLC40A1	2.42e-04	171	79	4	508b41e3ad2638f9dd546d251b13ff60fc8c3207
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TLR7 SIGLEC1 SIRPA SLC40A1	2.48e-04	172	79	4	f0e767a20d93e546ce278db67dbd779cc68af533
ToppCell	droplet-Spleen-nan-21m-Myeloid-macrophage\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLU ARHGAP28 SIRPA RTN1	2.48e-04	172	79	4	4fe5b91e4871bc6c5be57eb5b8bb04815b2fb80d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRFN2 PARD6G ARHGAP28 ARMH4	2.48e-04	172	79	4	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HLA-DQB2 TLR7 SIGLEC1 RTN1	2.48e-04	172	79	4	f6b4754a7e4b3e38030316a0ae00d932bfa87e41
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	TDRD7 ZBED4 CLU CCNB3	2.53e-04	173	79	4	42c911ed16fabdabef063830e8407192d8bde950
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-B_atypical\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HLA-DQB1 HLA-DQB2 FCRL5 TMEM231	2.53e-04	173	79	4	f135cc9dcf34f33ced3210171ab40ae6d77cfae0
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-B_atypical-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HLA-DQB1 HLA-DQB2 FCRL5 TMEM231	2.53e-04	173	79	4	23248019c819f6e38337dcc4edb763ef1992e89e
ToppCell	(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts\|(0)_Normal/No_Treatment / Stress and Cell class	SLIT2 NPTN PARD6G NCAM1	2.53e-04	173	79	4	c2a0f674681836b5a868c13f67caa7d555ef6519
ToppCell	droplet-Thymus-nan-3m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP28 SIRPA RTN1 SLC40A1	2.53e-04	173	79	4	63f03abca84ae021ff34ff34537838aa8a1ccd11
ToppCell	facs-Heart-LA-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAGAP TLR7 SIGLEC1 SIRPA	2.59e-04	174	79	4	30c083fe4711735e83dccfd00fcd746ae673d353
ToppCell	facs-Heart-LA-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAGAP TLR7 SIGLEC1 SIRPA	2.59e-04	174	79	4	46d19c1144fff19be682b7ba59d4c3e014f79e15
ToppCell	facs-Heart-LA-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAGAP TLR7 SIGLEC1 SIRPA	2.59e-04	174	79	4	1802a52552256d1e25d8b328ba62dcfe41671900
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TLR7 SIGLEC1 SIRPA SLC40A1	2.59e-04	174	79	4	f520b79d277e286c9bb5d091e6c94e7ec7e46699
Drug	(1R,3R)-5-[(2E)-2-[(1E,7aS)-1-(6-hydroxy-6-methylheptan-2-ylidene)-7a-methyl-2,3,3a,5,6,7-hexahydroinden-4-ylidene]ethylidene]-2-methylenecyclohexane-1,3-diol	HSPD1 NPTN NCAM1	4.56e-06	10	78	3	CID011553431
Disease	frailty measurement	ANK3 HLA-DQB1 HLA-DQB2 NCAM1	3.85e-07	23	78	4	EFO_0009885
Disease	type 1 diabetes mellitus, latent autoimmune diabetes in adults	HLA-DQB1 HLA-DQB2	4.12e-05	4	78	2	EFO_0009706, MONDO_0005147
Disease	narcolepsy-cataplexy syndrome, age at onset	HLA-DQB1 HLA-DQB2	6.86e-05	5	78	2	EFO_0004847, MONDO_0016158
Disease	HPV seropositivity	HLA-DQB1 HLA-DQB2	6.86e-05	5	78	2	EFO_0004510
Disease	level of coiled-coil domain-containing protein 134 in blood serum	HLA-DQB1 HLA-DQB2	6.86e-05	5	78	2	OBA_2044258
Disease	Varicella zoster virus seropositivity	HLA-DQB1 HLA-DQB2	6.86e-05	5	78	2	EFO_0009340
Disease	lupus nephritis	HLA-DQB1 HLA-DQB2 ARMH4	9.16e-05	33	78	3	EFO_0005761
Disease	antibody measurement, Epstein-Barr virus infection	HLA-DQB1 HLA-DQB2	1.03e-04	6	78	2	EFO_0000769, EFO_0004556
Disease	pneumocystosis (biomarker_via_orthology)	HLA-DQB1 HLA-DQB2	1.03e-04	6	78	2	DOID:11339 (biomarker_via_orthology)
Disease	pemphigus	HLA-DQB1 HLA-DQB2	1.03e-04	6	78	2	EFO_1000749
Disease	late-onset Alzheimers disease	LRFN2 ANK3 HMCN1 LRIG1 CLU CFAP74	1.26e-04	292	78	6	EFO_1001870
Disease	lymphoid leukemia	LRIG1 HLA-DQB1 HLA-DQB2	1.40e-04	38	78	3	EFO_0004289
Disease	antinuclear antibody measurement	HLA-DQB1 HLA-DQB2	1.44e-04	7	78	2	EFO_0005949
Disease	Anti-Helicobacter pylori IgG measurement	HLA-DQB1 HLA-DQB2	1.44e-04	7	78	2	EFO_0009352
Disease	cervical cancer	HLA-DQB1 HLA-DQB2 SIRPA	1.64e-04	40	78	3	MONDO_0002974
Disease	IgG index	HLA-DQB1 HLA-DQB2	1.91e-04	8	78	2	EFO_0006929
Disease	cardiovascular measurement, left ventricular function	SLIT2 EPHA4	1.91e-04	8	78	2	EFO_0004295, EFO_0004298
Disease	PAX-interacting protein 1 measurement	HLA-DQB1 HLA-DQB2	1.91e-04	8	78	2	EFO_0801868
Disease	soluble CD163 measurement	HLA-DQB1 HLA-DQB2	1.91e-04	8	78	2	EFO_0020072
Disease	gdnf family receptor alpha-1 measurement	HLA-DQB1 HLA-DQB2	1.91e-04	8	78	2	EFO_0020400
Disease	fibroblast growth factor 23 measurement	HLA-DQB1 HLA-DQB2 SLC40A1	2.03e-04	43	78	3	EFO_0009381
Disease	zinc fingers and homeoboxes protein 3 measurement	HLA-DQB1 HLA-DQB2	2.45e-04	9	78	2	EFO_0803299
Disease	Epstein Barr virus nuclear antigen 1 IgG measurement	HLA-DQB1 HLA-DQB2	2.45e-04	9	78	2	EFO_0007790
Disease	inclusion body myositis	HLA-DQB1 HLA-DQB2	2.45e-04	9	78	2	EFO_0007323
Disease	head and neck malignant neoplasia	HLA-DQB1 HLA-DQB2	2.45e-04	9	78	2	EFO_0006859
Disease	HLA class II histocompatibility antigen, DQ alpha 2 chain measurement	HLA-DQB1 HLA-DQB2	2.45e-04	9	78	2	EFO_0801686
Disease	seropositivity measurement	HLA-DQB1 HLA-DQB2	2.45e-04	9	78	2	EFO_0007034
Disease	latent autoimmune diabetes in adults, type 2 diabetes mellitus	HLA-DQB1 HLA-DQB2	2.45e-04	9	78	2	EFO_0009706, MONDO_0005148
Disease	proteinuria (biomarker_via_orthology)	HAVCR1 CLU	3.06e-04	10	78	2	DOID:576 (biomarker_via_orthology)
Disease	peptidoglycan recognition protein 1 measurement	HLA-DQB1 HLA-DQB2	3.06e-04	10	78	2	EFO_0020624
Disease	CCL19 measurement	HLA-DQB1 HLA-DQB2	3.06e-04	10	78	2	EFO_0009415
Disease	cervical carcinoma, Cervical Intraepithelial Neoplasia Grade 2/3	HLA-DQB1 HLA-DQB2	3.06e-04	10	78	2	EFO_0001061, EFO_1000166
Disease	secreted and transmembrane protein 1 measurement	HLA-DQB1 HLA-DQB2	3.06e-04	10	78	2	EFO_0021852
Disease	C-reactive protein measurement	NCOA6 MYPOP LRFN2 PTPRF ANK3 HLA-DQB1 HLA-DQB2 SLC38A4 TAF4 IL36G ARMH4	3.21e-04	1206	78	11	EFO_0004458
Disease	chronic bronchitis	HLA-DQB1 HLA-DQB2	3.74e-04	11	78	2	EFO_0006505
Disease	apolipoprotein M measurement	HLA-DQB1 HLA-DQB2	3.74e-04	11	78	2	EFO_0021945
Disease	cAMP-specific 3',5'-cyclic phosphodiesterase 4D measurement	HLA-DQB1 HLA-DQB2	3.74e-04	11	78	2	EFO_0020224
Disease	head and neck squamous cell carcinoma	HLA-DQB1 HLA-DQB2	3.74e-04	11	78	2	EFO_0000181
Disease	pars orbitalis volume measurement	SLIT2 FCRL5	3.74e-04	11	78	2	EFO_0010320
Disease	uveitis (implicated_via_orthology)	HLA-DQB1 HLA-DQB2	3.74e-04	11	78	2	DOID:13141 (implicated_via_orthology)
Disease	phospholipids in large LDL measurement	HAVCR1 HLA-DQB1 HLA-DQB2	3.78e-04	53	78	3	EFO_0022174
Disease	diet measurement	NCOA6 PTPRF ANK3 MUC17 HLA-DQB1 HLA-DQB2 ARID2 PIGS NCAM1 EPHA4	4.35e-04	1049	78	10	EFO_0008111
Disease	rac GTPase-activating protein 1 measurement	HLA-DQB1 HLA-DQB2	4.48e-04	12	78	2	EFO_0801985
Disease	phospholipids in LDL measurement	HAVCR1 HLA-DQB1 HLA-DQB2	4.94e-04	58	78	3	EFO_0022294
Disease	phospholipids in small LDL measurement	HAVCR1 HLA-DQB1 HLA-DQB2	5.19e-04	59	78	3	EFO_0022297
Disease	rheumatoid arthritis, smoking status measurement, ACPA-positive rheumatoid arthritis	HLA-DQB1 HLA-DQB2	5.28e-04	13	78	2	EFO_0000685, EFO_0006527, EFO_0009459
Disease	Genetic chronic primary adrenal insufficiency	HLA-DQB1 HLA-DQB2	5.28e-04	13	78	2	Orphanet_101960
Disease	Schizophrenia	NPTN ARHGAP32 ANK3 CLU CTCF HLA-DQB1 NCAM1 ADGRF4 CFAP65	5.32e-04	883	78	9	C0036341
Disease	oral cavity cancer	HLA-DQB1 HLA-DQB2	6.15e-04	14	78	2	EFO_0005570
Disease	C-C motif chemokine 19 measurement	HLA-DQB1 HLA-DQB2	6.15e-04	14	78	2	EFO_0008047
Disease	oligoclonal band measurement, multiple sclerosis	HLA-DQB1 HLA-DQB2	6.15e-04	14	78	2	EFO_0005206, MONDO_0005301
Disease	liver neoplasm	HLA-DQB1 HLA-DQB2	7.08e-04	15	78	2	EFO_1001513
Disease	Non-steroidal anti-inflammatory and antirheumatic product use measurement	HLA-DQB1 HLA-DQB2	7.08e-04	15	78	2	EFO_0009935
Disease	Churg-Strauss syndrome	HLA-DQB1 HLA-DQB2	7.08e-04	15	78	2	EFO_0007208
Disease	autism spectrum disorder (implicated_via_orthology)	ARHGAP32 TSHZ3 LRFN2 TSC1	7.18e-04	152	78	4	DOID:0060041 (implicated_via_orthology)
Disease	pemphigus vulgaris	HLA-DQB1 HLA-DQB2	8.08e-04	16	78	2	EFO_0004719
Disease	gastroparesis	HLA-DQB1 HLA-DQB2	8.08e-04	16	78	2	EFO_1000948
Disease	Cannabis use	IPO8 NCAM1	8.08e-04	16	78	2	EFO_0007585
Disease	Endometrioma	NCOA6 SMPDL3A ARHGAP28 SLC40A1	8.90e-04	161	78	4	C0269102
Disease	Endometriosis	NCOA6 SMPDL3A ARHGAP28 SLC40A1	8.90e-04	161	78	4	C0014175
Disease	nephrotic syndrome	HLA-DQB1 HLA-DQB2 ADGRF4	8.92e-04	71	78	3	EFO_0004255
Disease	Antihistamine use measurement	HLA-DQB1 HLA-DQB2	9.14e-04	17	78	2	EFO_0009943
Disease	high altitude adaptation	HLA-DQB1 HLA-DQB2	9.14e-04	17	78	2	EFO_0009105
Disease	response to interferon-beta, anti-drug antibody measurement	HLA-DQB1 HLA-DQB2	9.14e-04	17	78	2	EFO_0010559, GO_0035456
Disease	Graves disease, thyrotoxic periodic paralysis	HLA-DQB1 HLA-DQB2	9.14e-04	17	78	2	EFO_0004237, MONDO_0019201
Disease	serum IgG measurement	HLA-DQB1 HLA-DQB2	1.03e-03	18	78	2	EFO_0004565
Disease	tropical spastic paraparesis	HLA-DQB1 HLA-DQB2	1.03e-03	18	78	2	EFO_0007527
Disease	Carcinoma of bladder	TSC1 EPHA4	1.03e-03	18	78	2	C0699885
Disease	asparaginase hypersensitivity	HLA-DQB1 HLA-DQB2 ARHGAP28	1.13e-03	77	78	3	EFO_0004881
Disease	hepatitis B virus infection	HLA-DQB1 HLA-DQB2	1.15e-03	19	78	2	EFO_0004197
Disease	carotid artery disease (is_marker_for)	HSPD1 HSPG2	1.15e-03	19	78	2	DOID:3407 (is_marker_for)
Disease	angiopoietin-1 receptor measurement	HLA-DQB1 HLA-DQB2	1.15e-03	19	78	2	EFO_0010600
Disease	age of onset of asthma	CTCF HLA-DQB1 HLA-DQB2	1.22e-03	79	78	3	OBA_2001001
Disease	neoplasm of mature B-cells	HLA-DQB1 HLA-DQB2	1.27e-03	20	78	2	EFO_0000096
Disease	polymyositis	HLA-DQB1 HLA-DQB2	1.27e-03	20	78	2	EFO_0003063
Disease	Autoimmune Hepatitis	HLA-DQB1 HLA-DQB2	1.40e-03	21	78	2	EFO_0005676
Disease	platelet measurement	PTPRF HLA-DQB1 HLA-DQB2 SIRPA RASL10B	1.50e-03	315	78	5	EFO_0005036
Disease	C-peptide measurement	HLA-DQB1 HLA-DQB2	1.54e-03	22	78	2	EFO_0005187
Disease	Henoch-Schoenlein purpura	HLA-DQB1 HLA-DQB2	1.54e-03	22	78	2	EFO_1000965
Disease	ubiquitin carboxyl-terminal hydrolase 25 measurement	HLA-DQB1 HLA-DQB2	1.54e-03	22	78	2	EFO_0021881
Disease	serum iron measurement	HLA-DQB1 HLA-DQB2 DCHS1	1.55e-03	86	78	3	EFO_0006332
Disease	feeling nervous measurement	NCOA6 HLA-DQB1 HLA-DQB2	1.61e-03	87	78	3	EFO_0009597
Disease	remission, hepatitis C virus infection	HLA-DQB1 HLA-DQB2	1.68e-03	23	78	2	EFO_0003047, EFO_0009785
Disease	gestational diabetes	HLA-DQB1 HLA-DQB2	1.68e-03	23	78	2	EFO_0004593
Disease	age-related hearing impairment	LRFN2 HLA-DQB1 HLA-DQB2 PIWIL1 PARD6G	1.70e-03	324	78	5	EFO_0005782
Disease	visceral adipose tissue measurement	SLIT2 LRFN2 HLA-DQB1 HLA-DQB2 CRYBG1 SIGLEC1	1.74e-03	481	78	6	EFO_0004765
Disease	chronic hepatitis B virus infection	HLA-DQB1 HLA-DQB2	1.83e-03	24	78	2	EFO_0004239
Disease	drug-induced liver injury	HLA-DQB1 HLA-DQB2	1.83e-03	24	78	2	EFO_0004228
Disease	lymphoma	HLA-DQB1 HLA-DQB2	1.83e-03	24	78	2	EFO_0000574
Disease	pre-eclampsia (is_implicated_in)	CLU HLA-DQB1	1.99e-03	25	78	2	DOID:10591 (is_implicated_in)
Disease	Abnormality of refraction	TDRD7 ARHGAP32 TSHZ3 PTPRF ANK3 CLU ARID2	2.03e-03	673	78	7	HP_0000539
Disease	lysophosphatidylethanolamine 16:0 measurement	HLA-DQB1 HLA-DQB2	2.15e-03	26	78	2	EFO_0010366
Disease	proline measurement	SLC38A4 NCAM1	2.15e-03	26	78	2	EFO_0009773
Disease	L lactate dehydrogenase measurement	HLA-DQB1 HLA-DQB2	2.15e-03	26	78	2	EFO_0004808
Disease	Alzheimer disease, age at onset	HSPG2 COL12A1 CLU DCHS1 EPHA4	2.18e-03	343	78	5	EFO_0004847, MONDO_0004975
Disease	Hodgkins lymphoma, multiple myeloma, non-Hodgkins lymphoma	HLA-DQB1 HLA-DQB2	2.49e-03	28	78	2	EFO_0000183, EFO_0001378, EFO_0005952
Disease	chronic kidney disease (biomarker_via_orthology)	HAVCR1 CLU	2.49e-03	28	78	2	DOID:784 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
IEFTIPTAVTIEVEP	nan	31	Q6ZRG5
PPLESLATVEETVVR	PPP2R1A	91	P30153
PVTVPVATTSVEELQ	CTCF	121	P49711
LTPRETVVPSVDIIS	ADGRG4	776	Q8IZF6
TTVVPLSFEVTPTVE	ARMH4	526	Q86TY3
PLIIAVTTVAITEPE	ADGRF4	526	Q8IZF3
PVSTSVVRVDSVPDV	ARID2	616	Q68CP9
PVTTPEEIAQVATIS	HSPD1	161	P10809
EVTPVVASTTVVPNI	CCNB3	116	Q8WWL7
VLPSLTVSRVIIPVS	C16orf46	376	Q6P387
DISSTVPIPEEEVVT	KPNA5	71	O15131
LLVTEAPSKPITVTV	HSPG2	1761	P98160
PQSSVVPVTVTVLDV	DCHS1	2581	Q96JQ0
ETPSLVVPLEDRVVS	LRIG1	691	Q96JA1
PPVSVITIRSDTDEE	HIPK1	901	Q86Z02
PVPELSTDTVINVIT	SMPDL3A	116	Q92484
PEETVPFVVTLRASV	CFAP65	1496	Q6ZU64
EPLEVTTNTVPSRII	EPHA4	526	P54764
VEPTVTISPSRTEAL	HLA-DQB2	126	P05538
DTISLSVIVPVSRPI	FCRL5	646	Q96RD9
RETPIVTVTPSSVSA	MUC3A	196	Q02505
PVSTLVTTLPITITR	MUC3A	1441	Q02505
VVRVPSVPETELTDQ	NOL6	116	Q9H6R4
ISVTLPPRVSEVIGT	ARHGAP32	911	A7KAX9
TIIIADSPSPAVSVI	HIPK3	856	Q9H422
ASETVISLIVTEPPT	LRIT1	336	Q9P2V4
RPVSSIIDVDLVPET	PARD6G	141	Q9BYG4
PEREVIVETISNPVT	HMCN1	3156	Q96RW7
PVVPEPEVTSIVATV	PRPF40A	311	O75400
PTSVRSIVTTLVPSE	NCOA6	1911	Q14686
TTLQRRVEPTVTISP	HLA-DQB1	121	P01920
RVEPTVTISPSRTEA	HLA-DQB1	126	P01920
PRSDSVTPVTVAVIT	IL36G	46	Q9NZH8
DLTSEPVTVREVTLP	COL12A1	1551	Q99715
VPIPPVITETRTEVV	ANK3	2156	Q12955
IIPVSVPVRTVDPTE	MIDEAS	526	Q6PJG2
VIPESSEVREVQLPT	CRYBG1	566	Q9Y4K1
TTVIPPSEEQTEITL	CFAP74	731	Q9C0B2
LKVEVTPTVPRISRT	FAM126B	301	Q8IXS8
PPIDLVVTETTATSV	PTPRF	321	P10586
EIFRTIIDRTVPPET	IPO8	231	O15397
IVVTITTSPALDSPV	OR4C5	66	Q8NGB2
LLTTPVEISTPVTIS	MUC17	236	Q685J3
TPLTSVPVSTRLVVS	MUC17	1101	Q685J3
TTILVSTTPVTRFPE	MUC17	3756	Q685J3
LMVPVTVVFTRESVP	PIGS	61	Q96S52
VRITITLTNELPPTS	PIWIL1	191	Q96J94
QITTPVKITLTEIEP	RTN1	276	Q16799
LETRVIGTSETPIII	RASL10B	111	Q96S79
TPIIARQVTPTTIIK	TAF4	511	O00268
ELAEPIAIRPTSETV	EPRS1	1111	P07814
SIPENSIIPEETLTV	SH3D21	311	A4FU49
REVSPEPIVSTVARL	TAGAP	351	Q8N103
TSQTLETVPLIPEVV	NBR1	801	Q14596
TTPIVTTVPTVTTVR	HAVCR1	131	Q96D42
EPTIPVTELDVVLTA	PITRM1	566	Q5JRX3
LSETIRVPPTLEVTQ	SIRPA	246	P78324
GVEVRVTPTRTEIII	RPS3	36	P23396
IVPETSPESVPIISV	SLC40A1	441	Q9NP59
IIPIQEPDVTTTASR	SI	796	P14410
TVTSVKVSELREIPP	TDRD7	741	Q8NHU6
TVPIVLFPIRTSVIT	SLC38A4	426	Q969I6
VRPVPTTVRFVDSLI	NIF3L1	6	Q9GZT8
PPSIRVVVTVEQTEE	SPTLC1	441	O15269
IPVISTSETSVPLKV	SLFNL1	306	Q499Z3
DSDPITVTVPVEVSR	CLU	411	P10909
VIVCDVVSSLPPTII	NCAM1	136	P13591
LSEITTAEAEPVVPR	TSC1	486	Q92574
TTLPVEEPIVSTDEV	TRAPPC14	136	Q8WVR3
VPRSDSVAILETIPV	ARHGAP28	236	Q9P2N2
TVIESSPESPVTITE	GEMIN5	616	Q8TEQ6
VTSEEVIIRDSPVLP	NPTN	151	Q9Y639
LTEIPTNLPETITEI	SLIT2	291	O94813
TLVTVTEEPRVPTIA	SIGLEC1	131	Q9BZZ2
VTAVPTVLPSTLTEL	TLR7	216	Q9NYK1
VETPVTPTITTLLDE	TSHZ3	426	Q63HK5
VSRPIVVSKPVTVSR	ZNF512B	296	Q96KM6
VVTTIPVTVTPRGDL	TMEM231	296	Q9H6L2
RPVSLFSTPVVEEVE	GTF3C1	2056	Q12789
VPAVTTPVLAESILE	SON	1331	P18583
IPSPDRITEESVSVV	ZBED4	216	O75132
PEPVVTVRTQETDVV	GARIN5B	586	Q8N5Q1
PPERAVLVSEVTTTS	LRFN2	421	Q9ULH4
IVITTEPTDDTTVPE	MYOZ2	246	Q9NPC6
VEITPEPVSVVAAVV	MYPOP	331	Q86VE0