Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeleton-nuclear membrane anchor activity	SYNE1 SYNE3 SYNE2	2.93e-06	5	134	3	GO:0140444
GeneOntologyMolecularFunction	antigen binding	IGHV4-38-2 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-30-4 IGHV4-28 IGHV4-4	4.35e-05	190	134	8	GO:0003823
GeneOntologyMolecularFunction	interleukin-27 receptor binding	EBI3 IL27	4.47e-05	2	134	2	GO:0045523
GeneOntologyMolecularFunction	protein-membrane adaptor activity	SYNE1 RB1CC1 SYNE3 SYNE2	2.33e-04	45	134	4	GO:0043495
GeneOntologyMolecularFunction	prostaglandin E receptor activity	PTGER1 PTGER3	4.41e-04	5	134	2	GO:0004957
GeneOntologyBiologicalProcess	nucleus localization	SYNE1 SYNE3 MTOR SYNE2 DMD	9.51e-06	44	134	5	GO:0051647
GeneOntologyBiologicalProcess	immunoglobulin mediated immune response	CD19 IGHV4-38-2 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-30-4 IGHV4-28 IGHV4-4	2.36e-05	235	134	9	GO:0016064
GeneOntologyBiologicalProcess	B cell mediated immunity	CD19 IGHV4-38-2 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-30-4 IGHV4-28 IGHV4-4	3.16e-05	244	134	9	GO:0019724
GeneOntologyBiologicalProcess	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	CD19 EBI3 MTOR IGHV4-38-2 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-30-4 IGHV4-28 IGHV4-4 IL27	4.94e-05	462	134	12	GO:0002460
GeneOntologyBiologicalProcess	urinary bladder smooth muscle contraction	CACNA1C PTGER3 ATP2B4	5.65e-05	12	134	3	GO:0014832
GeneOntologyBiologicalProcess	mitochondrial fusion	MFN1 PARL MIEF1 PID1	9.52e-05	37	134	4	GO:0008053
GeneOntologyBiologicalProcess	urinary tract smooth muscle contraction	CACNA1C PTGER3 ATP2B4	1.15e-04	15	134	3	GO:0014848
GeneOntologyCellularComponent	immunoglobulin complex	IGHV4-38-2 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-30-4 IGHV4-28 IGHV4-4	1.19e-05	166	134	8	GO:0019814
GeneOntologyCellularComponent	microtubule organizing center attachment site	SYNE1 SYNE3 SYNE2	4.09e-05	11	134	3	GO:0034992
GeneOntologyCellularComponent	meiotic nuclear membrane microtubule tethering complex	SYNE1 SYNE3 SYNE2	4.09e-05	11	134	3	GO:0034993
GeneOntologyCellularComponent	nuclear membrane protein complex	SYNE1 SYNE3 SYNE2	4.09e-05	11	134	3	GO:0106083
GeneOntologyCellularComponent	nuclear membrane microtubule tethering complex	SYNE1 SYNE3 SYNE2	4.09e-05	11	134	3	GO:0106094
Domain	KASH	SYNE1 SYNE3 SYNE2	1.19e-06	4	126	3	IPR012315
Domain	KASH	SYNE1 SYNE3 SYNE2	1.19e-06	4	126	3	PS51049
Domain	KASH	SYNE1 SYNE3 SYNE2	1.19e-06	4	126	3	SM01249
Domain	KASH	SYNE1 SYNE3 SYNE2	1.19e-06	4	126	3	PF10541
Domain	FAT	TRRAP MTOR PRKDC	5.91e-06	6	126	3	PS51189
Domain	FATC	TRRAP MTOR PRKDC	5.91e-06	6	126	3	PS51190
Domain	FAT	TRRAP MTOR PRKDC	5.91e-06	6	126	3	PF02259
Domain	PIK-rel_kinase_FAT	TRRAP MTOR PRKDC	5.91e-06	6	126	3	IPR003151
Domain	FATC_dom	TRRAP MTOR PRKDC	5.91e-06	6	126	3	IPR003152
Domain	PIK_FAT	TRRAP MTOR PRKDC	5.91e-06	6	126	3	IPR014009
Domain	FATC	TRRAP MTOR PRKDC	5.91e-06	6	126	3	SM01343
Domain	Spectrin	SYNE1 SYNE3 SYNE2 DMD	1.58e-05	23	126	4	PF00435
Domain	-	RELCH XPO4 CUL9 TRRAP WDFY4 MTOR ULK4 MMS19 PRKDC	1.99e-05	222	126	9	1.25.10.10
Domain	Spectrin_repeat	SYNE1 SYNE3 SYNE2 DMD	4.12e-05	29	126	4	IPR002017
Domain	SPEC	SYNE1 SYNE3 SYNE2 DMD	6.13e-05	32	126	4	SM00150
Domain	Spectrin/alpha-actinin	SYNE1 SYNE3 SYNE2 DMD	6.13e-05	32	126	4	IPR018159
Domain	ARM-like	RELCH XPO4 CUL9 TRRAP WDFY4 MTOR ULK4 MMS19 PRKDC	9.11e-05	270	126	9	IPR011989
Domain	ARM-type_fold	RALGAPA1 RELCH XPO4 CUL9 TRRAP WDFY4 MTOR ULK4 MMS19 PRKDC	1.02e-04	339	126	10	IPR016024
Domain	HEAT_REPEAT	RELCH MTOR ULK4 MMS19 PRKDC	1.10e-04	70	126	5	PS50077
Domain	Prostglndn_DP_rcpt	PTGER1 PTGER3	1.35e-04	3	126	2	IPR001244
Domain	-	TRRAP MTOR PRKDC	1.57e-04	16	126	3	1.10.1070.11
Domain	PI3Kc	TRRAP MTOR PRKDC	1.57e-04	16	126	3	SM00146
Domain	PI3_PI4_kinase	TRRAP MTOR PRKDC	2.27e-04	18	126	3	PF00454
Domain	PI3_4_KINASE_1	TRRAP MTOR PRKDC	2.27e-04	18	126	3	PS00915
Domain	PI3_4_KINASE_2	TRRAP MTOR PRKDC	2.27e-04	18	126	3	PS00916
Domain	PI3/4_kinase_cat_dom	TRRAP MTOR PRKDC	2.27e-04	18	126	3	IPR000403
Domain	PI3_4_KINASE_3	TRRAP MTOR PRKDC	2.27e-04	18	126	3	PS50290
Domain	VDCC_L_a1su	CACNA1C CACNA1S	2.69e-04	4	126	2	IPR005446
Domain	FATC	MTOR PRKDC	4.46e-04	5	126	2	PF02260
Domain	ACTININ_2	SYNE1 SYNE2 DMD	4.81e-04	23	126	3	PS00020
Domain	ACTININ_1	SYNE1 SYNE2 DMD	4.81e-04	23	126	3	PS00019
Domain	Actinin_actin-bd_CS	SYNE1 SYNE2 DMD	4.81e-04	23	126	3	IPR001589
Domain	DH_1	ARHGEF40 PREX1 ARHGEF6 SOS2	8.65e-04	63	126	4	PS00741
Domain	Ca_chan_IQ	CACNA1C CACNA1S	9.27e-04	7	126	2	SM01062
Domain	Ca_chan_IQ	CACNA1C CACNA1S	9.27e-04	7	126	2	PF08763
Domain	VDCC_a1su_IQ	CACNA1C CACNA1S	9.27e-04	7	126	2	IPR014873
Domain	GPHH	CACNA1C CACNA1S	9.27e-04	7	126	2	PF16905
Domain	GPHH_dom	CACNA1C CACNA1S	9.27e-04	7	126	2	IPR031649
Domain	CH	SYNE1 SYNE2 DMD ARHGEF6	9.73e-04	65	126	4	SM00033
Domain	Prostanoid_rcpt	PTGER1 PTGER3	1.23e-03	8	126	2	IPR008365
Domain	RhoGEF	ARHGEF40 PREX1 ARHGEF6 SOS2	1.28e-03	70	126	4	PF00621
Domain	CH	SYNE1 SYNE2 DMD ARHGEF6	1.28e-03	70	126	4	PF00307
Domain	DH_2	ARHGEF40 PREX1 ARHGEF6 SOS2	1.28e-03	70	126	4	PS50010
Domain	-	ARHGEF40 PREX1 ARHGEF6 SOS2	1.35e-03	71	126	4	1.20.900.10
Domain	DH-domain	ARHGEF40 PREX1 ARHGEF6 SOS2	1.35e-03	71	126	4	IPR000219
Domain	-	SYNE1 SYNE2 DMD ARHGEF6	1.35e-03	71	126	4	1.10.418.10
Domain	CH	SYNE1 SYNE2 DMD ARHGEF6	1.50e-03	73	126	4	PS50021
Domain	CH-domain	SYNE1 SYNE2 DMD ARHGEF6	1.66e-03	75	126	4	IPR001715
Domain	VDCCAlpha1	CACNA1C CACNA1S	1.96e-03	10	126	2	IPR002077
Domain	GDS_CDC24_CS	PREX1 ARHGEF6 SOS2	2.29e-03	39	126	3	IPR001331
Domain	Leu-rich_rpt	MXRA5 ECM2 NLRP1 LINGO2 TLR10 RXFP2 NLRP5	2.44e-03	271	126	7	IPR001611
Domain	LDLR_class-A_CS	RXFP2 LRP2 LRP6	2.47e-03	40	126	3	IPR023415
Domain	VWA	MATN4 VWA7 ITGAM VWA5B1	2.51e-03	84	126	4	SM00327
Domain	Ldl_recept_a	RXFP2 LRP2 LRP6	3.46e-03	45	126	3	PF00057
Domain	-	RXFP2 LRP2 LRP6	3.68e-03	46	126	3	4.10.400.10
Domain	Ldl_recept_b	LRP2 LRP6	3.90e-03	14	126	2	PF00058
Domain	LDLRB	LRP2 LRP6	3.90e-03	14	126	2	PS51120
Domain	LDLRA_1	RXFP2 LRP2 LRP6	4.16e-03	48	126	3	PS01209
Domain	LDrepeatLR_classA_rpt	RXFP2 LRP2 LRP6	4.41e-03	49	126	3	IPR002172
Domain	LDLa	RXFP2 LRP2 LRP6	4.41e-03	49	126	3	SM00192
Domain	LDLRA_2	RXFP2 LRP2 LRP6	4.41e-03	49	126	3	PS50068
Domain	PI3/4_kinase_CS	MTOR PRKDC	4.48e-03	15	126	2	IPR018936
Domain	LY	LRP2 LRP6	4.48e-03	15	126	2	SM00135
Domain	LDLR_classB_rpt	LRP2 LRP6	4.48e-03	15	126	2	IPR000033
Domain	VWF_A	MATN4 VWA7 ITGAM VWA5B1	4.54e-03	99	126	4	IPR002035
Domain	LRR_8	MXRA5 ECM2 LINGO2 TLR10 RXFP2	6.09e-03	171	126	5	PF13855
Domain	-	MXRA5 ECM2 NLRP1 LINGO2 TLR10 RXFP2 NLRP5	6.14e-03	321	126	7	3.80.10.10
Domain	Channel_four-helix_dom	CACNA1C CACNA1S KCNA6	6.73e-03	57	126	3	IPR027359
Domain	-	CACNA1C CACNA1S KCNA6	6.73e-03	57	126	3	1.20.120.350
Pathway	REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS	CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	8.63e-08	53	100	7	MM15716
Pathway	REACTOME_CD22_MEDIATED_BCR_REGULATION	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	1.50e-07	35	100	6	MM17219
Pathway	REACTOME_CLASSICAL_ANTIBODY_MEDIATED_COMPLEMENT_ACTIVATION	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.96e-07	39	100	6	MM17212
Pathway	REACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	7.13e-07	45	100	6	MM14912
Pathway	REACTOME_FCGR_ACTIVATION	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	1.06e-06	48	100	6	MM17214
Pathway	REACTOME_COMPLEMENT_CASCADE	CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.12e-06	84	100	7	MM14653
Pathway	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.15e-06	54	100	6	MM14655
Pathway	REACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.67e-06	56	100	6	MM14815
Pathway	REACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	3.29e-06	58	100	6	MM14914
Pathway	REACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	4.02e-06	60	100	6	MM14872
Pathway	REACTOME_FCERI_MEDIATED_MAPK_ACTIVATION	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	4.02e-06	60	100	6	MM14913
Pathway	REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR	PSME1 CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	4.08e-06	131	100	8	MM15717
Pathway	REACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION	PSME1 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	1.07e-05	107	100	7	MM14915
Pathway	REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL	CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	4.82e-05	135	100	7	MM14781
Pathway	REACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING	PSME1 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	9.40e-05	150	100	7	MM14889
Pathway	REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL	ITGAM IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	1.30e-04	158	100	7	MM14812
Pathway	KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_PI3K_SIGNALING_PATHWAY	FLT3LG MTOR SOS2	1.48e-04	15	100	3	M47475
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	1.58e-04	114	100	6	MM14814
Pathway	WP_GPCRS_SMALL_LIGAND	PTGER1 PTGER3 S1PR4	2.62e-04	18	100	3	MM15858
Pathway	WP_SMALL_LIGAND_GPCRS	PTGER1 PTGER3 S1PR4	3.09e-04	19	100	3	M39728
Pathway	WP_ENVELOPE_PROTEINS_AND_THEIR_POTENTIAL_ROLES_IN_EDMD_PHYSIOPATHOLOGY	SYNE1 SYNE3 SYNE2 SOS2	3.10e-04	46	100	4	M39828
Pathway	KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY	CACNA1C CACNA1S	7.34e-04	6	100	2	M47762
Pathway	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	ARHGEF40 PREX1 ARHGEF6 SOS2	8.05e-04	59	100	4	M11215
Pubmed	Cloning, sequencing and expression of the rearranged MOPC 315 VH gene segment.	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.33e-14	7	137	6	2497341
Pubmed	Model-building studies of antigen-binding sites: the hapten-binding site of mopc-315.	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.33e-14	7	137	6	268248
Pubmed	Amino acid sequence of the precursor region of MOPC-315 mouse immunoglobulin heavy chain.	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.33e-14	7	137	6	414225
Pubmed	The idiotypic network and the internal image: possible regulation of a germ-line network by paucigene encoded Ab2 (anti-idiotypic) antibodies in the GAT system.	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.33e-14	7	137	6	3937730
Pubmed	The structure of the expressible VH gene from a hybridoma producing monoclonal antibodies against porcine transferrin.	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.33e-14	7	137	6	2587273
Pubmed	Amino-acid sequence of the variable region of the heavy (alpha) chain of a mouse myeloma protein with anti-hapten activity.	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.33e-14	7	137	6	4524622
Pubmed	A new germline VH36-60 gene is used in the neonatal primary and adult memory response to (T,G)-A--L.	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.33e-14	7	137	6	1683681
Pubmed	Structure and function of immunoglobulin genes and precursors.	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	6.93e-13	10	137	6	428562
Pubmed	Chromosomal organization of the human VH4 gene family. Location of individual gene segments.	IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-30-2	2.30e-10	4	137	4	8454861
Pubmed	Early onset of somatic mutation in immunoglobulin VH genes during the primary immune response.	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.37e-10	22	137	6	2499654
Pubmed	Blockade of prostaglandin E2 signaling through EP1 and EP3 receptors attenuates Flt3L-dependent dendritic cell development from hematopoietic progenitor cells.	FLT3LG PTGER1 PTGER3	5.95e-07	5	137	3	22110249
Pubmed	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.	SYNE1 SYNE3 SYNE2	5.95e-07	5	137	3	18396275
Pubmed	IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes.	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	6.31e-07	77	137	6	15608191
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZHX3 SYNE1 CUL9 CEP192 POGZ SNX19 RRS1 MTCL1 SELENOI MARCHF4 PLXNB3	6.98e-07	407	137	11	12693553
Pubmed	Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.	SYNE1 SYNE3 SYNE2	1.19e-06	6	137	3	33058875
Pubmed	TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.	SYNE1 SYNE3 SYNE2	1.19e-06	6	137	3	18827015
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CUL9 CEP192 TRRAP HDAC7 FASN ARHGEF40 SYNE3 SARS2 KLHL36 MTOR RRS1 COQ4 ULK4 PRKDC LTBP4 PREX1 ABCC10	1.78e-06	1105	137	17	35748872
Pubmed	Nuclear membrane proteins with potential disease links found by subtractive proteomics.	SYNE1 SYNE2 TMEM209	7.03e-06	10	137	3	12958361
Pubmed	Tel2 regulates the stability of PI3K-related protein kinases.	TRRAP MTOR PRKDC	7.03e-06	10	137	3	18160036
Pubmed	Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.	TRRAP MTOR PRKDC	9.64e-06	11	137	3	20427287
Pubmed	A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.	SYNE1 SYNE3 SYNE2	9.64e-06	11	137	3	22826121
Pubmed	Mammalian target of rapamycin signaling inhibition ameliorates vascular calcification via Klotho upregulation.	KL MTOR	1.54e-05	2	137	2	26061549
Pubmed	Temporal expression of calcium channel subunits in satellite cells and bone marrow mesenchymal cells.	CACNA1C CACNA1S	1.54e-05	2	137	2	25277766
Pubmed	Dual TORK/DNA-PK inhibition blocks critical signaling pathways in chronic lymphocytic leukemia.	MTOR PRKDC	1.54e-05	2	137	2	27235137
Pubmed	DMD mutation and LTBP4 haplotype do not predict onset of left ventricular dysfunction in Duchenne muscular dystrophy.	DMD LTBP4	1.54e-05	2	137	2	29766838
Pubmed	T and B lymphocyte depletion has a marked effect on the fibrosis of dystrophic skeletal muscles in the scid/mdx mouse.	PRKDC DMD	1.54e-05	2	137	2	17668421
Pubmed	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.	SYNE1 SYNE2	1.54e-05	2	137	2	11792814
Pubmed	A single nucleotide deletion in the skeletal muscle-specific calcium channel transcript of muscular dysgenesis (mdg) mice.	CACNA1C CACNA1S	1.54e-05	2	137	2	1281468
Pubmed	Characterization of EP receptor subtypes responsible for prostaglandin E2-induced pain responses by use of EP1 and EP3 receptor knockout mice.	PTGER1 PTGER3	1.54e-05	2	137	2	11375261
Pubmed	Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.	SYNE1 SYNE2	1.54e-05	2	137	2	24931616
Pubmed	Targeting latent TGFβ release in muscular dystrophy.	DMD LTBP4	1.54e-05	2	137	2	25338755
Pubmed	Influenza A virus induces interleukin-27 through cyclooxygenase-2 and protein kinase A signaling.	EBI3 IL27	1.54e-05	2	137	2	22343630
Pubmed	DNA-PK, Nuclear mTOR, and the Androgen Pathway in Prostate Cancer.	MTOR PRKDC	1.54e-05	2	137	2	32209447
Pubmed	The roles of prostaglandin EP 1 and 3 receptors in the control of human myometrial contractility.	PTGER1 PTGER3	1.54e-05	2	137	2	22162473
Pubmed	IL-27 structural analysis demonstrates similarities with ciliary neurotrophic factor (CNTF) and leads to the identification of antagonistic variants.	EBI3 IL27	1.54e-05	2	137	2	20974977
Pubmed	Transfer of type II collagen-induced arthritis from DBA/1 to severe combined immunodeficiency mice can be prevented by blockade of Mac-1.	ITGAM PRKDC	1.54e-05	2	137	2	8690467
Pubmed	Characteristics of thermoregulatory and febrile responses in mice deficient in prostaglandin EP1 and EP3 receptors.	PTGER1 PTGER3	1.54e-05	2	137	2	12837930
Pubmed	Human muscle-derived cell populations isolated by differential adhesion rates: phenotype and contribution to skeletal muscle regeneration in Mdx/SCID mice.	PRKDC DMD	1.54e-05	2	137	2	21854253
Pubmed	[Expression of EBI3 and p28 mRNA in the brain and spinal cord of chronic model of experimental autoimmune encephalomyelitis in C57BL/6J mice].	EBI3 IL27	1.54e-05	2	137	2	19060371
Pubmed	LSD1 negatively regulates autophagy through the mTOR signaling pathway in ovarian cancer cells.	MTOR KDM1A	1.54e-05	2	137	2	29749504
Pubmed	Impaired duodenal bicarbonate secretion and mucosal integrity in mice lacking prostaglandin E-receptor subtype EP(3).	PTGER1 PTGER3	1.54e-05	2	137	2	10535876
Pubmed	Gastric ulcerogenic responses following barrier disruption in knockout mice lacking prostaglandin EP1 receptors.	PTGER1 PTGER3	1.54e-05	2	137	2	11966527
Pubmed	Transplantation-based screen identifies inducers of muscle progenitor cell engraftment across vertebrate species.	PRKDC DMD	1.54e-05	2	137	2	37018075
Pubmed	Cytoskeletal interactions at the nuclear envelope mediated by nesprins.	SYNE1 SYNE3	1.54e-05	2	137	2	22518138
Pubmed	Modulation of inflammation by interleukin-27.	EBI3 IL27	1.54e-05	2	137	2	23904441
Pubmed	IGHV4-39 deletion polymorphism does not associate with risk or outcome of multiple sclerosis.	IGHV4-39 IGHV4-28	1.54e-05	2	137	2	20471699
Pubmed	Tissue-specific inactivation of HAT cofactor TRRAP reveals its essential role in B cells.	TRRAP CD19	1.54e-05	2	137	2	24675885
Pubmed	Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.	SYNE1 SYNE2	1.54e-05	2	137	2	22768332
Pubmed	KDM1A inhibition augments the efficacy of rapamycin for the treatment of endometrial cancer.	MTOR KDM1A	1.54e-05	2	137	2	34673129
Pubmed	Induction of IL-6 via the EP3 subtype of prostaglandin E receptor in rat adjuvant-arthritic synovial cells.	PTGER1 PTGER3	1.54e-05	2	137	2	11235015
Pubmed	Co-ordinated expression of lymphoid and myeloid specific transcription factors during B-1b cell differentiation into mononuclear phagocytes in vitro.	ITGAM CD19	1.54e-05	2	137	2	18710404
Pubmed	Anorexia and cachexia in prostaglandin EP1 and EP3 subtype receptor knockout mice bearing a tumor with high intrinsic PGE2 production and prostaglandin related cachexia.	PTGER1 PTGER3	1.54e-05	2	137	2	15943039
Pubmed	Enhanced expression of IL-27 mRNA in human newborns.	EBI3 IL27	1.54e-05	2	137	2	18167155
Pubmed	Emerging Roles of IL-27 in Trophoblast Cells and Pregnancy Complications.	EBI3 IL27	1.54e-05	2	137	2	39422056
Pubmed	Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.	SYNE1 SYNE2	1.54e-05	2	137	2	17267447
Pubmed	Nesprins: tissue-specific expression of epsilon and other short isoforms.	SYNE1 SYNE2	1.54e-05	2	137	2	24718612
Pubmed	Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.	SYNE1 SYNE2	1.54e-05	2	137	2	24586179
Pubmed	Muscle protein synthesis, mTORC1/MAPK/Hippo signaling, and capillary density are altered by blocking of myostatin and activins.	MTOR DMD	1.54e-05	2	137	2	23115080
Pubmed	Endogenous cardiac Ca2+ channels do not overcome the E-C coupling defect in immortalized dysgenic muscle cells: evidence for a missing link.	CACNA1C CACNA1S	1.54e-05	2	137	2	7635187
Pubmed	Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy.	KL DMD	1.54e-05	2	137	2	27154199
Pubmed	Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.	SYNE1 SYNE2	1.54e-05	2	137	2	17761684
Pubmed	Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.	SYNE1 SYNE2	1.54e-05	2	137	2	31578382
Pubmed	Chemokine/ITGA4 Interaction Directs iPSC-Derived Myogenic Progenitor Migration to Injury Sites in Aging Muscle for Regeneration.	PRKDC DMD	1.54e-05	2	137	2	37508502
Pubmed	Complement receptor 3 deficiency influences lesion progression during Leishmania major infection in BALB/c mice.	ITGAM PRKDC	1.54e-05	2	137	2	19797068
Pubmed	Dihydropyridine receptor gene expression in skeletal muscle from mdx and control mice.	CACNA1S DMD	1.54e-05	2	137	2	9540851
Pubmed	Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27.	EBI3 IL27	1.54e-05	2	137	2	16880260
Pubmed	Association of CACNA1C and SYNE1 in offspring of patients with psychiatric disorders.	CACNA1C SYNE1	1.54e-05	2	137	2	27620326
Pubmed	The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus.	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-28 IGHV4-4	3.12e-05	91	137	5	9841928
Pubmed	Sorcin associates with the pore-forming subunit of voltage-dependent L-type Ca2+ channels.	CACNA1C CACNA1S	4.61e-05	3	137	2	9668070
Pubmed	Facilitation by endogenous prostaglandins of capsaicin-induced gastric protection in rodents through EP2 and IP receptors.	PTGER1 PTGER3	4.61e-05	3	137	2	12604682
Pubmed	Cellular localization of mRNAs for prostaglandin E receptor subtypes in mouse gastrointestinal tract.	PTGER1 PTGER3	4.61e-05	3	137	2	9124591
Pubmed	Involvement of Cox-2 in the metastatic potential of chemotherapy-resistant breast cancer cells.	PTGER1 PTGER3	4.61e-05	3	137	2	21813027
Pubmed	IL-35 Suppresses Lipopolysaccharide-Induced Airway Eosinophilia in EBI3-Deficient Mice.	EBI3 IL27	4.61e-05	3	137	2	27881708
Pubmed	The effects of prostaglandin analogues on prostanoid EP1, EP2, and EP3 receptor-deficient mice.	PTGER1 PTGER3	4.61e-05	3	137	2	16877408
Pubmed	Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).	CACNA1C CACNA1S	4.61e-05	3	137	2	17767505
Pubmed	The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells.	PRKDC KDM1A	4.61e-05	3	137	2	22464800
Pubmed	Bleomycin-induced E prostanoid receptor changes alter fibroblast responses to prostaglandin E2.	PTGER1 PTGER3	4.61e-05	3	137	2	15843564
Pubmed	NOX4 inhibition promotes the remodeling of dystrophic muscle.	DMD LTBP4	4.61e-05	3	137	2	36278481
Pubmed	B cell-specific deficiencies in mTOR limit humoral immune responses.	CD19 MTOR	4.61e-05	3	137	2	23858034
Pubmed	Gene network analysis of oxidative stress-mediated drug sensitivity in resistant ovarian carcinoma cells.	PRKDC ARHGEF6	4.61e-05	3	137	2	19918261
Pubmed	Triad proteins and intracellular Ca2+ transients during development of human skeletal muscle cells in aneural and innervated cultures.	CACNA1C CACNA1S	4.61e-05	3	137	2	11206130
Pubmed	Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.	CACNA1C CACNA1S	4.61e-05	3	137	2	2173707
Pubmed	The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.	SYNE1 SYNE2	4.61e-05	3	137	2	16079285
Pubmed	mRNA for cardiac calcium channel is expressed during development of skeletal muscle.	CACNA1C CACNA1S	4.61e-05	3	137	2	8381753
Pubmed	Direct activation of mTOR in B lymphocytes confers impairment in B-cell maturation andloss of marginal zone B cells.	CD19 MTOR	4.61e-05	3	137	2	21674478
Pubmed	Oral Escherichia coli colonization factor antigen I fimbriae ameliorate arthritis via IL-35, not IL-27.	EBI3 IL27	4.61e-05	3	137	2	24337375
Pubmed	Essential role for CAML in follicular B cell survival and homeostasis.	CD19 PRKDC	4.61e-05	3	137	2	22351938
Pubmed	The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction.	SYNE3 SYNE2	4.61e-05	3	137	2	23336069
Pubmed	Functional prostaglandin E (EP) receptors in human penile corpus cavernosum.	PTGER1 PTGER3	4.61e-05	3	137	2	14562138
Pubmed	Combined deficiency of alpha and epsilon sarcoglycan disrupts the cardiac dystrophin complex.	SGCE DMD	4.61e-05	3	137	2	21890494
Pubmed	Human pluripotent stem cell-derived myogenic progenitors undergo maturation to quiescent satellite cells upon engraftment.	PRKDC DMD	4.61e-05	3	137	2	35395188
Pubmed	Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy.	PRKDC DMD	4.61e-05	3	137	2	29242210
Pubmed	Angiotensin II suppresses long-term depression in the lateral amygdala of mice via L-type calcium channels.	CACNA1C CACNA1S	4.61e-05	3	137	2	17289261
Pubmed	Interleukin-27 controls basal pain threshold in physiological and pathological conditions.	EBI3 IL27	4.61e-05	3	137	2	30038376
Pubmed	Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.	SYNE1 SYNE2	4.61e-05	3	137	2	10878022
Pubmed	The Histone Demethylase LSD1 Regulates B Cell Proliferation and Plasmablast Differentiation.	CD19 KDM1A	4.61e-05	3	137	2	30232138
Pubmed	The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.	SYNE1 SYNE2	4.61e-05	3	137	2	12408964
Pubmed	Plasma membrane Ca2+ ATPase 1 (PMCA1) but not PMCA4 is critical for B-cell development and Ca2+ homeostasis in mice.	CD19 ATP2B4	4.61e-05	3	137	2	33098669
Pubmed	Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.	SYNE1 SYNE2	4.61e-05	3	137	2	17462627
Pubmed	Cell-mediated exon skipping normalizes dystrophin expression and muscle function in a new mouse model of Duchenne Muscular Dystrophy.	PRKDC DMD	4.61e-05	3	137	2	38438561
Cytoband	14q32.33	IGHV4-38-2 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-30-4 IGHV4-30-2 IGHV4-28 IGHV4-4	3.24e-08	228	137	9	14q32.33
Cytoband	8q11	RB1CC1 PRKDC	1.32e-04	6	137	2	8q11
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE1 SYNE3 SYNE2	6.74e-07	4	101	3	1252
GeneFamily	Immunoglobulin heavy locus at 14q32.33	IGHV4-38-2 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-30-4 IGHV4-30-2 IGHV4-28 IGHV4-4	1.03e-06	187	101	9	349
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF40 PREX1 ARHGEF6 SOS2	5.07e-04	66	101	4	722
GeneFamily	Prostaglandin (prostanoid) receptors	PTGER1 PTGER3	1.08e-03	9	101	2	207
GeneFamily	Low density lipoprotein receptors	LRP2 LRP6	2.32e-03	13	101	2	634
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZHX3 ZFHX3	3.09e-03	15	101	2	529
ToppCell	BAL-Mild-Lymphocyte-B\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	TLR10 CD19 EBI3 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	8.42e-08	181	135	8	700adfb41e4e377530f0dd31be89e12f109f3469
ToppCell	Mild-Lymphoid-B\|Mild / Condition, Lineage, Cell class and cell subclass	TLR10 CD19 EBI3 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	9.16e-08	183	135	8	9b64d2d143525e6f48a191facfd101462ff36324
ToppCell	Mild_COVID-19-B_cell\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	TLR10 CD19 EBI3 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	9.16e-08	183	135	8	dea119e2988e954475f557f0bbe12556a83e81a4
ToppCell	Mild-Lymphoid-B-\|Mild / Condition, Lineage, Cell class and cell subclass	TLR10 CD19 EBI3 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	9.16e-08	183	135	8	b5740f05a4dcdbbf24f7bf7a3f57ac01a5e75f60
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TLR10 CD19 EBI3 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	9.56e-08	184	135	8	3f8a359e40bebe58545f708682e5e5d1b70cf5cb
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TLR10 CD19 EBI3 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	9.56e-08	184	135	8	64bede8db709fd32f40c03265b96f0b12155bb8a
ToppCell	BAL-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	TLR10 CD19 EBI3 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	9.96e-08	185	135	8	609080adb2cfb105bb7b8efb617553833299f371
ToppCell	Mild_COVID-19-B_cell-B_cell\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	TLR10 CD19 EBI3 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	1.04e-07	186	135	8	855a5a00ba2aa1b5c63b8db56d026ddecc546050
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DHRS3 ECM2 GREB1L SYNE3 RXFP2 DMD LTBP4 PID1	1.13e-07	188	135	8	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	Biopsy_Other_PF-Immune-Plasma_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	CD19 GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	1.49e-07	195	135	8	d0305c6a68c9e361507b04db94f86873085d49b3
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CD19 GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	1.49e-07	195	135	8	f3f7f1a77a1edd2b50a8211c76fe289738eb04cf
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	WDFY4 TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	1.61e-07	197	135	8	2662138671262b30508c5759038bcdcfe6551696
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	1.61e-07	197	135	8	9fe1b757f76c2d43d39aa9ac500eaba98723985c
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPR37L1 KL KCNA6 LRP2 IGSF21 UNC80 PLXNB3	7.04e-07	164	135	7	3caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-30-2 IGHV4-28	1.22e-06	178	135	7	107dae8b00c4257697a63700e72bb434cdb8406f
ToppCell	cellseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	1.47e-06	183	135	7	5ab4aa0304b832f98fff89b6c24ad5b7dd014c11
ToppCell	droplet-Pancreas-Endocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIN1 KLHL5 ARHGEF40 SLC9A5 DCHS1 CARD6 LTBP4	1.58e-06	185	135	7	512a195ebbae445afe3722a3943020080daf2f3c
ToppCell	healthy_donor-Lymphocytic-Plasma_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	1.75e-06	188	135	7	bd53b0371154cff680226897b61c9809a239d1b6
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-B_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WDFY4 TLR10 CD19 IGHV4-39 IGHV4-30-2 IGHV4-28 S1PR4	1.88e-06	190	135	7	e1af324b4522045875fb64766cf118cd7b41704a
ToppCell	Biopsy_IPF-Immune-Plasma_cells\|Biopsy_IPF / Sample group, Lineage and Cell type	GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.31e-06	196	135	7	a1b6a8000b86efcb07843998aa3a49bb1f54bcda
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	2.39e-06	197	135	7	88b29d205237f07a9a26cc15a1cf4ed4816a4c4b
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	2.39e-06	197	135	7	76465bb2408c7c75f694e8f7cf1a606b796afc3a
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.39e-06	197	135	7	1e63879633f20646e44873ae6b662f6faf4806fd
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_cell-B_mature\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	WDFY4 TLR10 CD19 IGHV4-61 IGHV4-39 IGHV4-28 S1PR4	2.39e-06	197	135	7	da175e66d0a743a1b91d46f224b5ff1d37aa5410
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell-IgA_Plasmablast\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.39e-06	197	135	7	fdbf4eb9fa5aefb4ffb307494fe4774bf5e0aaeb
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_cell-B_naive\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	2.47e-06	198	135	7	79c690d21d3420d0bb1a3b3b4ea2c9aa3810a219
ToppCell	Control-Control-Lymphocyte-B-Plasmablast\|Control / Disease, condition lineage and cell class	GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.56e-06	199	135	7	c11aa8bca3723a886e7082ae48bb922dd8396be4
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_cell-B_naive\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TLR10 CD19 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.56e-06	199	135	7	8e02d3a066e79e0f2024a10738e0ea070513ef19
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	FLT3LG NOX5 KIAA1586 ARHGAP11A PREX1 S1PR4	9.47e-06	160	135	6	1a9329d8183296f36928bd9e96f10db9f04ce326
ToppCell	healthy_donor-Lymphocytic-Plasma_cell-IgM_Plasmablast\|healthy_donor / Disease condition, Lineage, Cell class and subclass	GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-28 IGHV4-4	1.17e-05	166	135	6	2b7b580bec8d9467b0deaf97098065f72dbf2a4f
ToppCell	10x5'-GI_large-bowel\|World / Manually curated celltypes from each tissue	FEV IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-30-2 IGHV4-28	1.25e-05	168	135	6	1290c909655bc37f6b8bf216d18127a21b99e9c0
ToppCell	BAL-Mild-Lymphocyte-B\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31	1.29e-05	169	135	6	307571e57c3bfdf15f0fe1a8b36585e8e4f8a207
ToppCell	facs-Heart-RA-24m-Lymphocytic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S WDFY4 CD19 RXFP2 IGSF21 S1PR4	1.29e-05	169	135	6	dcf92121fb00e3b6498e2648363e90ac044ea396
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31	1.34e-05	170	135	6	ee2ee67d90ae4596de8ccd620e37c82cf51651d4
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31	1.34e-05	170	135	6	d7ca0c6ce5d2b7de99346f87e07aa7fe728fa08a
ToppCell	BAL-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31	1.34e-05	170	135	6	52787f6d529c285d9f0c04cc022710ead5b89b3f
ToppCell	metastatic_Brain-B_lymphocytes-Plasma_cells\|metastatic_Brain / Location, Cell class and cell subclass	CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	1.34e-05	170	135	6	53634da9e9c72f6400639954c286c6e38ea5a188
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	WDFY4 TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-30-2	1.43e-05	172	135	6	172e3c78f8e97988a4fd8624514e731282ddc16d
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	WDFY4 TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-30-2	1.43e-05	172	135	6	5fb0ea6145892a258696197b3feed9760187e712
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	WDFY4 TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-30-2	1.43e-05	172	135	6	2214cc37d7c21b868768d3f74ca4631d339d37b3
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	WDFY4 TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-30-2	1.43e-05	172	135	6	07620728a6cdeea805e1365e588be096c17a370c
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-30-2 IGHV4-28	1.48e-05	173	135	6	7e6bfe85f60834f317941b70d6e0dc3bd527d293
ToppCell	Control-CD4+_T_activated\|Control / Disease group and Cell class	FLT3LG B3GNTL1 DHRS3 LKAAEAR1 HDAC7 EBI3	1.53e-05	174	135	6	2b683e81b315ad22555314433aed5681feb48da8
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C MRS2 PTPRT B3GNT6 MTOR ULK4	1.53e-05	174	135	6	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	wk_15-18-Hematologic_Lymphocytic-B-CD5+_CCL22+_mature_B\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TLR10 CD19 EBI3 IGHV4-61 IGHV4-59 IGHV4-28	1.58e-05	175	135	6	fa53ea81ad943a2cd266114829135cbcbcf2f634
ToppCell	metastatic_Brain-B_lymphocytes-MALT_B_cells\|metastatic_Brain / Location, Cell class and cell subclass	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	1.63e-05	176	135	6	50e207403d48ce1b55a78897adb5519a2430a626
ToppCell	Control-Lymphoid_P-Plasmablast\|Control / Disease group, lineage and cell class	GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-4	1.63e-05	176	135	6	4b4416f342b732d2cc60133838728880326257d8
ToppCell	Control-Lymphoid_P\|Control / Disease group, lineage and cell class	GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-4	1.63e-05	176	135	6	d895a6b295cd649273ff80ad7785a3e0ae4c728a
ToppCell	(2)_Plasma_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-4	1.68e-05	177	135	6	ed3c936bb69f9bc7291b4f6cde1d204078117c48
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-Immature_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WDFY4 TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-39	1.74e-05	178	135	6	2e51c1596022b7047994ee13c18375bad19a54a5
ToppCell	BAL-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLT3LG LKAAEAR1 SYNE1 HDAC7 SYNE2 ATP2B4	1.79e-05	179	135	6	a634ca46ffc394c5f5215fc5d8eae4a77819af9c
ToppCell	BAL-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLT3LG LKAAEAR1 SYNE1 HDAC7 SYNE2 ATP2B4	1.79e-05	179	135	6	35f014b6e752626909d829c5ab9bb761c1f3e3dc
ToppCell	BAL-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD19 IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28 IGHV4-4	1.85e-05	180	135	6	6a777a308fa3160d31eda468db930e71862020b2
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WDFY4 TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-39	1.91e-05	181	135	6	e7d9910f6143055645b6f03b1018282e6c215f10
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR37L1 MATN4 KCNA6 IGSF21 UNC80 PLXNB3	1.97e-05	182	135	6	d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR37L1 MATN4 KCNA6 IGSF21 UNC80 PLXNB3	1.97e-05	182	135	6	6fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR37L1 MATN4 KCNA6 IGSF21 UNC80 PLXNB3	1.97e-05	182	135	6	e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR37L1 MATN4 KCNA6 IGSF21 UNC80 PLXNB3	1.97e-05	182	135	6	82ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-B_cells-Pre-B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WDFY4 CD19 IGHV4-39 IGHV4-30-2 IGHV4-28 S1PR4	2.16e-05	185	135	6	0fa7970709dc957dea95fabbd83263a0335babd5
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-30-2 IGHV4-28	2.16e-05	185	135	6	08bc817908076734d66f2805cb954141f2cc5a18
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-30-2 IGHV4-28	2.16e-05	185	135	6	1704a12153a9b107bf03ecccd1a036cf61334d7a
ToppCell	10x5'-Liver-Lymphocytic_B_plasma\|Liver / Manually curated celltypes from each tissue	GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-30-2 IGHV4-28	2.22e-05	186	135	6	a2c7430781f432c9c90ac4d620f4518ff767a223
ToppCell	healthy_donor-Lymphocytic-Plasma_cell-IgA_Plasmablast\|healthy_donor / Disease condition, Lineage, Cell class and subclass	GPRC5D IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-4	2.22e-05	186	135	6	e2c050ba02e1f84f0b7258dc92e7ff6ab349ff67
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AVPR1B SLC7A2 SGCE FEV SELENOI IGSF21	2.22e-05	186	135	6	4bb54043f944a979db91bde9a86dd66f498c7658
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR37L1 MATN4 KCNA6 IGSF21 UNC80 PLXNB3	2.36e-05	188	135	6	8385fd384fc55e3b17802bb6698eb93b2c16d7f2
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AVPR1B ITFG1 SLC7A2 MORF4L2 FEV IGSF21	2.36e-05	188	135	6	e99e3765b48392c987cf0c5ccbded0655637d7b7
ToppCell	10x5'-blood-Lymphocytic_B-Naive_B_cells\|blood / Manually curated celltypes from each tissue	WDFY4 TLR10 CD19 IGHV4-59 IGHV4-30-2 IGHV4-28	2.36e-05	188	135	6	2b3560b28f9df6f4d4a3e0a4acfa6c7d964ad0fe
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR37L1 MATN4 KCNA6 IGSF21 UNC80 PLXNB3	2.36e-05	188	135	6	cb9d0b48e2fd9cc576132803273b9c0382900944
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DHRS3 ECM2 GREB1L DMD LTBP4 PID1	2.51e-05	190	135	6	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM WDFY4 EBI3 IGSF21 PREX1 PID1	2.51e-05	190	135	6	788ff9d8888d2dd25b7e1d7e0e5d57751ce86f19
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR37L1 PTGER1 KCNA6 IGSF21 UNC80 PLXNB3	2.51e-05	190	135	6	e2481bd5166fde2cdc0c3824894f2bccb8294fdd
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RIN1 KL DCHS1 DMD LTBP4 ATP2B4	2.51e-05	190	135	6	3cf464664d6aa22b212e60b70885953887e92483
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM WDFY4 EBI3 IGSF21 PREX1 PID1	2.58e-05	191	135	6	baa70781633a3fe5bf987f9d8dff3884f5167e7f
ToppCell	cellseq2-Immune-Lymphocytic_B-Lymphocytic_B\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TLR10 CD19 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	2.58e-05	191	135	6	17746a32f723c078aba1f7e320b0e3f1ab8bf5c6
ToppCell	cellseq2-Immune-Lymphocytic_B\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TLR10 CD19 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	2.58e-05	191	135	6	c2c450df810f83163987cd0f7ed9b50025cd3de1
ToppCell	COVID-19_Severe-B_intermediate\|World / disease group, cell group and cell class	WDFY4 PTPRT TLR10 CD19 EBI3 DMD	2.58e-05	191	135	6	f226fd69a26124ba98e4544f550b89a08e6a3708
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM WDFY4 EBI3 IGSF21 PREX1 PID1	2.66e-05	192	135	6	86d792682ba51696f503c79625dd20f87bcf651f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM WDFY4 EBI3 IGSF21 PREX1 PID1	2.66e-05	192	135	6	d0ad6a205ad50a3c523fa68676996b289eabc5de
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ECM2 GREB1L SLC7A2 DMD LTBP4 PID1	2.74e-05	193	135	6	09a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM WDFY4 EBI3 IGSF21 PREX1 PID1	2.74e-05	193	135	6	f597fefc54327a1ad136e2f66b6e81cc5c761eb7
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	2.74e-05	193	135	6	282b47dae6043eabb1e13d41d91c07b5ec21cd65
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MXRA5 PTGER1 GREB1L SLC7A2 MYO3B VWA5B1	2.82e-05	194	135	6	4579b4a44f7c731553a284843c296866027d7c0e
ToppCell	COVID-19_Severe-B_intermediate\|COVID-19_Severe / disease group, cell group and cell class	WDFY4 PTPRT TLR10 CD19 EBI3 DMD	2.82e-05	194	135	6	3418308da7f1278ae2bf3fb61fc361b222e30043
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.82e-05	194	135	6	6ef4aeb8d8e35e4df58ff2a8256caa2113291de9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM WDFY4 EBI3 IGSF21 PREX1 PID1	2.82e-05	194	135	6	c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CD19 IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28	2.82e-05	194	135	6	a4a70369541876e1192df8828b63e3d1746ae3d9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NLRP1 ITGAM WDFY4 IGSF21 PREX1 PID1	2.90e-05	195	135	6	2d485373bfd9bb4bb9236bf0b31d03e132c8018f
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CD19 IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28 IGHV4-4	2.90e-05	195	135	6	df009b18898c10686f75cf72b4ec0eff18f5bb50
ToppCell	Healthy-B_intermediate\|World / disease group, cell group and cell class	WDFY4 PTPRT TLR10 CD19 SGCE DMD	2.90e-05	195	135	6	9de79e0bdd9063ae65e5edb89cc3fe6f9a8173bc
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.98e-05	196	135	6	c38e7f533c619afe008de0e99042f7180c2da918
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	WDFY4 TLR10 CD19 IGHV4-59 IGHV4-39 IGHV4-31	2.98e-05	196	135	6	e9fe5090452ffdde4bb81b62d57037d823281d00
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV4-61 IGHV4-59 IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	2.98e-05	196	135	6	fec21383435779bf4c632decd3d29c6ca7baebfb
ToppCell	Tracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C ZHX3 MXRA5 XPO4 SYNE3 SGCE	3.07e-05	197	135	6	4edf043e8f586fd375f56485841fe992a18bf853
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 PTPRT SYNE2 ULK4 DMD NEK11	3.07e-05	197	135	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Biopsy_Control_(H.)-Immune-Plasma_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	CD19 GPRC5D IGHV4-39 IGHV4-31 IGHV4-28 IGHV4-4	3.07e-05	197	135	6	275f38ed7e477000e864cecf9b7d49ae134c3b6a
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_cell-B_mature\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ITGAM WDFY4 TLR10 OR56B1 CD19 PREX1	3.16e-05	198	135	6	863765ccc0205dc28864dae85af339c283194c96
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_cell-B_mature\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	NAT16 TLR10 CD19 IGHV4-61 IGHV4-59 IGHV4-39	3.16e-05	198	135	6	d51ee880acc5804cd918105fac846a1528333d6c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NLRP1 ITGAM WDFY4 IGSF21 PREX1 PID1	3.25e-05	199	135	6	04adf46975aa4194ea40c7480f8a517def5d929c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SYNE1 GPR37L1 PTPRT IGSF21 UNC80 PLXNB3	3.25e-05	199	135	6	333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ITGAM WDFY4 TLR10 EBI3 IGSF21 PREX1	3.25e-05	199	135	6	744b63fba33b176ab7dde11646ccb313665505f7
Disease	waist circumference	RALGAPA1 OVCH2 LINGO2 PTPRT B3GNT6 FASN KLHL36 SYNE2 DMD PREX1	2.01e-05	429	129	10	EFO_0004342
Disease	Colorectal Carcinoma	RELCH ABCA13 SYNE1 PTPRT MFN1 KL ZKSCAN3 DCHS1 LRP2 DMD MMP11 IGSF21	6.21e-05	702	129	12	C0009402
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1C CACNA1S	1.13e-04	4	129	2	DOID:0060173 (implicated_via_orthology)
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	1.13e-04	4	129	2	cv:CN293514
Disease	pancreatic cancer (implicated_via_orthology)	FLT3LG MTOR	1.13e-04	4	129	2	DOID:1793 (implicated_via_orthology)
Disease	peptide measurement	SLC46A2 ABCA13 NLRP1 LINGO2 PTPRT	1.20e-04	109	129	5	EFO_0010520
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	1.88e-04	5	129	2	C1450051
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE1 SYNE2	1.88e-04	5	129	2	C0410190
Disease	Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	2.81e-04	6	129	2	cv:C0410189
Disease	interleukin-27 measurement	EBI3 IL27	2.81e-04	6	129	2	EFO_0010916
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE1 SYNE2	2.81e-04	6	129	2	C0410189
Disease	Muscular Dystrophy, Duchenne	DMD LTBP4	2.81e-04	6	129	2	C0013264
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	3.93e-04	7	129	2	C0751337
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CACNA1C CACNA1S DMD	5.24e-04	36	129	3	DOID:11723 (implicated_via_orthology)
Disease	progression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian carcinoma	INTS10 DMD ATP2B4	6.65e-04	39	129	3	EFO_0001075, EFO_0004920, GO_0097328, MONDO_0009354
Disease	alopecia areata (is_marker_for)	HDAC7 KDM1A	8.34e-04	10	129	2	DOID:986 (is_marker_for)
Disease	ankyrin-2 measurement	DDX59 ATP2B4	8.34e-04	10	129	2	EFO_0021874
Disease	temporomandibular joint disorder	RXFP2 DMD	8.34e-04	10	129	2	EFO_0005279
Disease	Sensory hearing loss	GJB3 LRP2	1.02e-03	11	129	2	C1691779
Disease	end stage renal disease (biomarker_via_orthology)	CYP2C18 KL LRP2	1.15e-03	47	129	3	DOID:783 (biomarker_via_orthology)
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 SYNE2	1.22e-03	12	129	2	DOID:11726 (implicated_via_orthology)
Disease	salicylurate measurement	CMBL CHTF18	1.43e-03	13	129	2	EFO_0010532
Disease	trait in response to apixaban	LINGO2 SYNE3 MYO3B DMD	1.66e-03	115	129	4	OBA_2050328
Disease	membranous glomerulonephritis (biomarker_via_orthology)	PTGER3 LRP2	1.67e-03	14	129	2	DOID:10976 (biomarker_via_orthology)
Disease	sphingomyelin 14:0 measurement	SYNE2 ZFHX3	2.47e-03	17	129	2	EFO_0010390
Disease	susceptibility to hepatitis B infection measurement	CACNA1C PTPRT PREX1	2.80e-03	64	129	3	EFO_0008405
Disease	vital capacity	CACNA1S HYKK SYNE1 LINGO2 LRP2 LRP6 ZFHX3 MTCL1 LTBP4 PID1 VWA5B1 ARHGEF6 SOS2	3.02e-03	1236	129	13	EFO_0004312
Disease	body weight	RALGAPA1 CACNA1C RELCH LINGO2 CEP192 PTPRT FASN MTOR ULK4 ZFHX3 DMD ATP2B4 NEK11	3.58e-03	1261	129	13	EFO_0004338
Disease	severe acute respiratory syndrome, COVID-19	MXRA5 WDFY4 MYO3B ZFHX3 SELENOI DMD S1PR4	3.59e-03	447	129	7	EFO_0000694, MONDO_0100096
Disease	Intellectual Disability	RALGAPA1 SYNE1 POGZ TRRAP FASN MTOR LRP2	3.59e-03	447	129	7	C3714756
Disease	stroke	SFXN4 WDFY4 ULK4 ZFHX3	3.74e-03	144	129	4	EFO_0000712
Disease	testosterone measurement	ZHX3 B3GNTL1 LINGO2 FASN ARHGEF40 SYNE2 RXFP2 ZFHX3 IGHV4-39 ATP2B4 ARHGEF6 ABCC10 SOS2	3.93e-03	1275	129	13	EFO_0004908
Disease	blood pressure	SYNE1 PREX1	4.14e-03	22	129	2	EFO_0004325
Disease	juvenile idiopathic arthritis	ABCA13 FASN PID1	4.22e-03	74	129	3	EFO_0002609

Protein segments in the cluster

Peptide	Gene	Start	Entry
LFSVWQEVFQLPRAQ	CHTF18	586	Q8WVB6
LFIQLNELLGWPQAL	SLC4A9	56	Q96Q91
LRWESFLQQQLQALP	DISP3	1141	Q9P2K9
EQVVVQLAALPWQLL	ARHGEF40	86	Q8TER5
FQEWLEQLNRLIRGP	ARHGEF6	536	Q15052
QIQLWQFLLELLADR	FEV	46	Q99581
IPNQFQNIWLHLITL	ABCA13	1536	Q86UQ4
QLNHLLLWLSPIRNQ	DMD	2336	P11532
LLWLSPIRNQLEIYN	DMD	2341	P11532
VLAIVPVNTLQNWLA	RAD54L2	331	Q9Y4B4
LFVAIVLTIWRQPQN	SLC7A2	536	P52569
ILWFRGLNRIQTQID	ATP2B4	1091	P23634
FLWRIEQLQKENSPR	MTCL1	1266	Q9Y4B5
VLLQQEWPRGENLFL	INTS10	591	Q9NVR2
LRATWLAQVLPLDQN	NOX5	296	Q96PH1
RLSKPNIFILNNRWD	MFN1	226	Q8IWA4
LPFFNVSLLDWINVQ	RB1CC1	301	Q8TDY2
WVVNQLLPQLIEIVG	RELCH	831	Q9P260
QEPWIQFATIRDNIL	ABCC10	671	Q5T3U5
WPLARRANSVVQLEI	DCHS1	746	Q96JQ0
LQAALQWLTQQPERE	KLHL36	211	Q8N4N3
SLWERLPQNNFLKVI	FANCF	191	Q9NPI8
LLLLQPWETQLQLTG	MATN4	11	O95460
RNPLLWLLQFLFQTD	DOLK	281	Q9UPQ8
VAAPRWVLSQVQLQE	IGHV4-31	11	P0DP07
VAAPRWVLSQVQLQE	IGHV4-4	11	A0A075B6R2
ETLPLLLQHLWQVNR	MMS19	571	Q96T76
VAAPRWVLSQLQLQE	IGHV4-30-2	11	A0A087WSY4
NLPCANVRQIILWVE	DDX59	411	Q5T1V6
VAAPRWVLSQVQLQE	IGHV4-30-4	11	P0DP06
VAAPRWVLSQVQLQE	IGHV4-61	11	A0A0C4DH41
EQLVALKPWITRQNF	FLT3LG	136	P49771
PANALLEIRPFQVWL	PID1	131	Q7Z2X4
LLRFWVNALKNPQLI	PLXNB3	1756	Q9ULL4
LLENFPEIIIWNCLN	KIAA1586	406	Q9HCI6
LRNPDVQGALWQIFL	OR3A2	301	P47893
RPLFLAVRLASWNQI	PTGER1	331	P34995
AVRLASLNQILDPWV	PTGER3	331	P43115
SQLLWHLQRQAPRLV	NAT16	311	Q8N8M0
TALQNLIPSLEQARW	NLRP1	461	Q9C000
RLQNQEIPSINIIWT	CSNKA2IP	186	A0A1B0GTH6
LLVAAPRWVLSQLQL	IGHV4-39	16	P01824
NTLILIIIWQNPSLQ	OR56B1	51	Q8NGI3
NLNLEQWLFRELPSQ	MRS2	156	Q9HD23
PENQIIEWFIQLLLG	NEK11	131	Q8NG66
VLFWQELDQPRAIAL	LRP6	131	O75581
WTQSLELPAERQNRL	LKAAEAR1	96	Q8TD35
DWDLVTRQKQLFQLP	MORF4L2	136	Q15014
CRLLWILQRQPTLQF	LINGO2	361	Q7L985
RLALNSFQEVWLPIN	NLRP5	701	P59047
VNPWLTQVRIFHQLR	LRP2	4311	P98164
RLALLQVPLQAWQLS	MSLNL	81	Q96KJ4
VAAPRWVLSQVQLQE	IGHV4-28	11	A0A0C4DH34
HIQLIVPLVLEQNLW	MIEF1	201	Q9NQG6
QLPWLARLIASVSQD	GREB1L	506	Q9C091
NIPNEETILNALLTW	KLHL5	376	Q96PQ7
VAAPRWVLSQVQLQE	IGHV4-59	11	P01825
VAAPRWVLSQVQLQE	IGHV4-38-2	11	P0DP08
VDIRARQLTLQWEPF	PTPRT	396	O14522
VRALLTWTLNPQIDN	IGSF21	301	Q96ID5
RENFIWNLKNVPLLE	HYKK	171	A2RU49
LPSQPFQRQVWLLFE	KCNA6	151	P17658
LFIRNRTLQLWLDNP	KDM1A	211	O60341
FQRILNLKPAQLLFW	CARD6	596	Q9BX69
LRNGWNLLDFIIVVV	CACNA1C	191	Q13936
QWNVLPTQLLFLLSV	GPRC5D	56	Q9NZD1
QPLWLTRLQDIANRV	CACNA1S	456	Q13698
RPLAIWLFIFNVSQQ	CD19	76	P15391
TLAVPELLLWQLAQE	GPR37L1	261	O60883
NIWNINLQLRPSLIT	GSTK1	31	Q9Y2Q3
QLPDVSLTFQAWRRL	IL27	86	Q8NEV9
RLSPLAERQLQVQWE	EBI3	136	Q14213
LQVLVSELIPWAVQN	COQ4	211	Q9Y3A0
SVPWAEVQSRLLALQ	ATG9B	326	Q674R7
IAPLAWINQENLESI	ECM2	526	O94769
SPSARWQRQDLLFQI	MARCHF4	261	Q9P2E8
VSLNWQPLTLQEARA	LTBP4	106	Q8N2S1
QTLLSVLNPTDRWLQ	CEP192	1391	Q8TEP8
NWLLVPLFLVVLVVN	SELENOI	321	Q9C0D9
FRQLESPNLRQLLSW	KL	386	Q9UEF7
VILLENLNRFWPIIQ	CUL9	1261	Q8IWT3
FNENLRILSSPWIQV	CYP2C18	201	P33260
PQVLLWEQQRLAGRL	HDAC7	446	Q8WUI4
NHRGPIQLWQFLLEL	ETV2	236	O00321
VNNLVSPVLFQEALW	FASN	736	P49327
VSFLALQQWFLQAPR	B3GNT6	21	Q6ZMB0
ISNIRLWALQLIFVT	GJB3	71	O75712
WILALAVLNSAVNPI	S1PR4	291	O95977
EQLNLVTTWLQLQIP	PSME1	126	Q06323
VEAVQLNQALLLLPW	DHRS3	251	O75911
QIDTWLQVIPQLIAR	MTOR	1931	P42345
NVLVFCLWRVPSLQR	PARL	176	Q9H300
TYRILRFPWQLVQEQ	MMP11	111	P24347
LTLLPQLQEAWQQRT	RSAD1	421	Q9HA92
LPAIISTWQELRQLQ	SARS2	86	Q9NP81
IQWFNKLSLNEPNRI	ARHGAP11A	811	Q6P4F7
RLLLTRPVWLQLQAN	RIN1	61	Q13671
QPVQLRILNVFRHWV	SOS2	681	Q07890
RRFLQWTELLDPTNV	SFXN4	41	Q6P4A7
LFWANLRAAINVNVL	TLR10	766	Q9BXR5
WRDLPQIINKRINFL	SYNE1	1746	Q8NF91
LPSLLQNRETFWAEQ	SYNE2	4801	Q8WXH0
QRPLQDLQLWKALAQ	SYNE3	446	Q6ZMZ3
TDNPIWNQILTFRIQ	FER1L5	366	A0AVI2
WNQILTFRIQLPCLS	FER1L5	371	A0AVI2
VGSIPLWLQNFVRIL	LIPI	86	Q6XZB0
TLLEFSQLQVPLTWQ	RIMBP3	1146	Q9UFD9
SQVLQEVNLPILTWE	OVCH2	191	Q7RTZ1
LAEWVLTQREQQLPV	POGZ	1031	Q7Z3K3
FEVQLVLRQALPNIW	PNLDC1	181	Q8NA58
RSLIQISIQEDPWNL	PREX1	1271	Q8TCU6
PLLWIFQQLFRRVQA	FTSJ3	166	Q8IY81
DLLANNILRIFVWVI	RXFP2	411	Q8WXD0
LQTWVLNQFRLVPLD	SLC9A5	381	Q14940
FLVPVRLNQTVIWDR	ITGAM	971	P11215
WQPERLNAINITSAL	SGCE	191	O43556
WINQLTPEQLLTQVF	B3GNTL1	156	Q67FW5
IVIQDIFGWQLPNTR	CMBL	46	Q96DG6
LAVALFQVLPQLLWD	AVPR1B	81	P47901
YWTEVLQPLQQRFLR	XPO4	771	Q9C0E2
WLEQPEVQLLLQTVI	UNC80	2731	Q8N2C7
EQFLTILPQELQAWV	ZSCAN21	91	Q9Y5A6
ILQLLPERIHQRWQF	RALGAPA1	91	Q6GYQ0
DVEILLNLRTNWPNT	RINT1	776	Q6NUQ1
LLINQLWQLPTERVE	RRS1	71	Q15050
NARNFFLLEWTLQPI	WDFY4	416	Q6ZS81
NLTSPQRWVQYLLLL	SNX19	866	Q92543
IDENPGLQLIIRNFW	PRKDC	2511	P78527
NWINETILVPLVQEI	TMEM209	341	Q96SK2
LEQFLTILPGNLQSW	ZKSCAN3	91	Q9BRR0
LFVLREPLGWNQVQV	SLC46A2	306	Q9BY10
QEWTAIIPNSQLIVI	ITFG1	531	Q8TB96
RHLLRQLFVQTQWPS	ZHX3	776	Q9H4I2
LLWPRQELQNLAQVA	VWA7	191	Q9Y334
QLFPRLWKILSDRQQ	TRRAP	2631	Q9Y4A5
FQLLIQHLRIAPNWD	ULK4	511	Q96C45
LDVQRWQIDLQPLLN	VWA5B1	701	Q5TIE3
SNLLNLPTRVIVVWF	ZFHX3	2276	Q15911
WILPNRRIINDLANT	MXRA5	611	Q9NR99
LFSWIVNRINTLLQP	MYO3B	691	Q8WXR4