Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	WAPL CHD2 BTAF1 HELQ ZRANB3 RAD54L	1.29e-05	127	81	6	GO:0008094
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	CHD2 BTAF1 ZRANB3 RAD54L	1.50e-05	37	81	4	GO:0140658
GeneOntologyMolecularFunction	ATP-dependent activity	WAPL MYO9A SMC6 MACF1 CHD2 BTAF1 KIF3C HELQ ZRANB3 RAD54L AFG1L	3.66e-05	614	81	11	GO:0140657
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	WAPL CHD2 BTAF1 HELQ ZRANB3 RAD54L TEFM	9.40e-05	262	81	7	GO:0140097
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR2 RYR3	9.70e-05	4	81	2	GO:0005219
GeneOntologyMolecularFunction	ATP-dependent DNA/DNA annealing activity	ZRANB3 RAD54L	1.61e-04	5	81	2	GO:0036310
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR2 RYR3	2.41e-04	6	81	2	GO:0048763
GeneOntologyMolecularFunction	ATP hydrolysis activity	SMC6 MACF1 CHD2 BTAF1 KIF3C HELQ RAD54L AFG1L	4.18e-04	441	81	8	GO:0016887
GeneOntologyMolecularFunction	helicase activity	CHD2 BTAF1 HELQ ZRANB3 RAD54L	4.60e-04	158	81	5	GO:0004386
GeneOntologyMolecularFunction	DNA/DNA annealing activity	ZRANB3 RAD54L	8.73e-04	11	81	2	GO:1990814
GeneOntologyMolecularFunction	annealing activity	ZRANB3 RAD54L	1.43e-03	14	81	2	GO:0140666
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	RYR2 RYR3	2.38e-03	18	81	2	GO:0015278
GeneOntologyCellularComponent	Z disc	SORBS2 DST SYNM PALLD RYR2 RYR3	3.07e-05	151	83	6	GO:0030018
GeneOntologyCellularComponent	I band	SORBS2 DST SYNM PALLD RYR2 RYR3	5.22e-05	166	83	6	GO:0031674
GeneOntologyCellularComponent	sarcomere	MTMR12 SORBS2 DST SYNM PALLD RYR2 RYR3	6.01e-05	249	83	7	GO:0030017
GeneOntologyCellularComponent	myofibril	MTMR12 SORBS2 DST SYNM PALLD RYR2 RYR3	1.07e-04	273	83	7	GO:0030016
GeneOntologyCellularComponent	contractile muscle fiber	MTMR12 SORBS2 DST SYNM PALLD RYR2 RYR3	1.55e-04	290	83	7	GO:0043292
GeneOntologyCellularComponent	Smc5-Smc6 complex	EID3 SMC6	5.51e-04	9	83	2	GO:0030915
GeneOntologyCellularComponent	axonal growth cone	SCN11A MYO9A PALLD	7.59e-04	45	83	3	GO:0044295
Domain	SNF2_N	CHD2 BTAF1 ZRANB3 RAD54L	1.19e-05	32	83	4	IPR000330
Domain	SNF2_N	CHD2 BTAF1 ZRANB3 RAD54L	1.19e-05	32	83	4	PF00176
Domain	Ryanrecept_TM4-6	RYR2 RYR3	5.84e-05	3	83	2	IPR009460
Domain	RyR	RYR2 RYR3	5.84e-05	3	83	2	PF02026
Domain	Ryanodine_rcpt	RYR2 RYR3	5.84e-05	3	83	2	IPR003032
Domain	RR_TM4-6	RYR2 RYR3	5.84e-05	3	83	2	PF06459
Domain	Ryan_recept	RYR2 RYR3	5.84e-05	3	83	2	IPR013333
Domain	Helicase_C	CHD2 BTAF1 HELQ ZRANB3 RAD54L	1.14e-04	107	83	5	PF00271
Domain	HELICc	CHD2 BTAF1 HELQ ZRANB3 RAD54L	1.14e-04	107	83	5	SM00490
Domain	Helicase_C	CHD2 BTAF1 HELQ ZRANB3 RAD54L	1.20e-04	108	83	5	IPR001650
Domain	HELICASE_CTER	CHD2 BTAF1 HELQ ZRANB3 RAD54L	1.25e-04	109	83	5	PS51194
Domain	HELICASE_ATP_BIND_1	CHD2 BTAF1 HELQ ZRANB3 RAD54L	1.25e-04	109	83	5	PS51192
Domain	DEXDc	CHD2 BTAF1 HELQ ZRANB3 RAD54L	1.25e-04	109	83	5	SM00487
Domain	Helicase_ATP-bd	CHD2 BTAF1 HELQ ZRANB3 RAD54L	1.30e-04	110	83	5	IPR014001
Domain	RIH_assoc	RYR2 RYR3	2.89e-04	6	83	2	PF08454
Domain	RIH_assoc-dom	RYR2 RYR3	2.89e-04	6	83	2	IPR013662
Domain	-	DST MACF1	2.89e-04	6	83	2	3.90.1290.10
Domain	RIH_dom	RYR2 RYR3	2.89e-04	6	83	2	IPR000699
Domain	Ins145_P3_rcpt	RYR2 RYR3	2.89e-04	6	83	2	IPR014821
Domain	Ryanodine_recept-rel	RYR2 RYR3	2.89e-04	6	83	2	IPR015925
Domain	-	RYR2 RYR3	2.89e-04	6	83	2	1.25.10.30
Domain	GAR	DST MACF1	2.89e-04	6	83	2	PS51460
Domain	-	DST MACF1	2.89e-04	6	83	2	3.30.920.20
Domain	RYDR_ITPR	RYR2 RYR3	2.89e-04	6	83	2	PF01365
Domain	GAS_dom	DST MACF1	2.89e-04	6	83	2	IPR003108
Domain	Ins145_P3_rec	RYR2 RYR3	2.89e-04	6	83	2	PF08709
Domain	GAS2	DST MACF1	2.89e-04	6	83	2	PF02187
Domain	GAS2	DST MACF1	2.89e-04	6	83	2	SM00243
Domain	HMGI/Y_DNA-bd_CS	KMT2C SETBP1 MBD2	3.48e-04	31	83	3	IPR000637
Domain	SH3	SORBS2 DST ARHGAP10 MAP3K9 MACF1 FNBP1L	4.02e-04	216	83	6	PS50002
Domain	Plectin_repeat	DST MACF1	4.04e-04	7	83	2	IPR001101
Domain	Plectin	DST MACF1	4.04e-04	7	83	2	PF00681
Domain	PLEC	DST MACF1	4.04e-04	7	83	2	SM00250
Domain	SH3_domain	SORBS2 DST ARHGAP10 MAP3K9 MACF1 FNBP1L	4.43e-04	220	83	6	IPR001452
Domain	MIR	RYR2 RYR3	8.58e-04	10	83	2	PS50919
Domain	MIR	RYR2 RYR3	8.58e-04	10	83	2	PF02815
Domain	MIR	RYR2 RYR3	8.58e-04	10	83	2	SM00472
Domain	MIR_motif	RYR2 RYR3	8.58e-04	10	83	2	IPR016093
Domain	-	PTPN4 MTMR12 ARHGAP10 ANLN ARHGEF18 FGD5 PLEKHA7	1.77e-03	391	83	7	2.30.29.30
Domain	AT_hook	KMT2C SETBP1	2.25e-03	16	83	2	PF02178
Domain	RhoGAP	MYO9A ARHGAP10 ARHGAP18	2.65e-03	62	83	3	SM00324
Domain	RhoGAP	MYO9A ARHGAP10 ARHGAP18	2.77e-03	63	83	3	PF00620
Domain	PH_dom-like	PTPN4 MTMR12 ARHGAP10 ANLN ARHGEF18 FGD5 PLEKHA7	2.86e-03	426	83	7	IPR011993
Domain	RHOGAP	MYO9A ARHGAP10 ARHGAP18	2.90e-03	64	83	3	PS50238
Domain	RhoGAP_dom	MYO9A ARHGAP10 ARHGAP18	2.90e-03	64	83	3	IPR000198
Domain	-	MYO9A ARHGAP10 ARHGAP18	2.90e-03	64	83	3	1.10.555.10
Domain	PH	ARHGAP10 ANLN ARHGEF18 FGD5 PLEKHA7	3.55e-03	229	83	5	PF00169
Domain	P-loop_NTPase	MYO9A SMC6 GNL2 CHD2 BTAF1 KIF3C HELQ ZRANB3 RAD54L AFG1L	4.28e-03	848	83	10	IPR027417
Pathway	REACTOME_RHO_GTPASE_CYCLE	UBXN11 DST MYO9A ARHGAP10 ANLN ARHGEF18 FGD5 ARHGAP18 RBM39	5.24e-05	439	56	9	MM15595
Pathway	REACTOME_RHO_GTPASE_CYCLE	UBXN11 DST MYO9A ARHGAP10 ANLN ARHGEF18 FGD5 FNBP1L ARHGAP18	6.35e-05	450	56	9	M27078
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	UBXN11 DST MYO9A ARHGAP10 ANLN ARHGEF18 FGD5 ARHGAP18 CDCA8 RBM39	2.08e-04	649	56	10	MM15690
Pathway	REACTOME_RHOA_GTPASE_CYCLE	MYO9A ARHGAP10 ANLN ARHGEF18 ARHGAP18	2.44e-04	142	56	5	MM15576
Pathway	REACTOME_RHOA_GTPASE_CYCLE	MYO9A ARHGAP10 ANLN ARHGEF18 ARHGAP18	3.05e-04	149	56	5	M41805
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	UBXN11 DST MYO9A ARHGAP10 ANLN ARHGEF18 FGD5 FNBP1L ARHGAP18 CDCA8	4.77e-04	720	56	10	M41838
Pathway	REACTOME_RND3_GTPASE_CYCLE	UBXN11 DST RBM39	6.11e-04	42	56	3	MM15677
Pathway	REACTOME_RND1_GTPASE_CYCLE	UBXN11 DST RBM39	6.55e-04	43	56	3	MM15679
Pathway	REACTOME_RND2_GTPASE_CYCLE	UBXN11 DST RBM39	7.01e-04	44	56	3	MM15678
Pathway	KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY	RYR2 RYR3	8.33e-04	11	56	2	M47958
Pathway	WP_CELLTYPE_DEPENDENT_SELECTIVITY_OF_CCK2R_SIGNALING	RYR2 RYR3	1.18e-03	13	56	2	M39589
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TOM1L2 KMT2C WAPL ANLN MATR3 SMC6 MAP3K9 ARHGEF18 MACF1 BOP1 CHD2 CCDC77 PLEKHA7 ZRANB3 KIAA0753	4.59e-08	1084	84	15	11544199
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MTMR12 SORBS2 DST MYO9A ANLN PRRC2C MATR3 MAP3K9 MACF1 RASSF8 PLEKHA7 PALLD KIAA0753	1.49e-07	861	84	13	36931259
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	LINS1 ZFHX4 RRP1B PRRC2C MATR3 MACF1 ZFC3H1 PALLD RBM39	2.35e-07	361	84	9	26167880
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	DST PRRC2C ZMYND8 RYR2 PDZD2 AFG1L	5.61e-07	123	84	6	26912792
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	BICD2 MTMR12 SORBS2 PRRC2C SPEG CUL9 MACF1 FHIP1B PDZD2	6.40e-07	407	84	9	12693553
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	WAPL ZFHX4 ARHGAP10 RBL1 PRRC2C PITX2 ZMYND8 CUL9 BTAF1 FNBP1L CDC25A MBD2	1.03e-06	857	84	12	25609649
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	TRAF7 DST AGPAT5 RRP1B ANLN RBL1 MAP3K9 BOP1 CHD2 CDCA8 PALLD PRX	1.92e-06	910	84	12	36736316
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	ZFHX4 RRP1B PRRC2C NOM1 MATR3 ZMYND8 GNL2 BOP1 MBD2 RBM39	2.05e-06	605	84	10	28977666
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	RRP1B PRRC2C NOM1 MATR3 SMC6 GNL2 MACF1 BOP1 ZFC3H1 CDCA8 TEFM	2.18e-06	759	84	11	35915203
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	SORBS2 DST SYNM ANLN PRRC2C MATR3 MACF1 BTAF1	2.68e-06	360	84	8	33111431
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	KMT2C DST RRP1B ARHGAP10 ANLN NOM1 ZMYND8 GNL2 MACF1 BOP1 CHD2 ZFC3H1 MBD2 PLEKHA7 TEFM	2.72e-06	1497	84	15	31527615
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	MYO9A PRRC2C NOM1 MATR3 GNL2 MSI1 ZFC3H1 RBM39 TEFM	2.75e-06	486	84	9	30940648
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	RRP1B PRRC2C NOM1 MATR3 GNL2 MACF1 CHD2 MSI1 RBM39 TEFM APOBEC3F	3.91e-06	807	84	11	22681889
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SORBS2 DST MATR3 MACF1 KIAA0753	4.81e-06	101	84	5	9872452
Pubmed	Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.	RYR2 RYR3	5.76e-06	2	84	2	21531043
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	5.76e-06	2	84	2	11002341
Pubmed	Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.	RYR2 RYR3	5.76e-06	2	84	2	16678258
Pubmed	Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.	RYR2 RYR3	5.76e-06	2	84	2	8898078
Pubmed	The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.	RYR2 RYR3	5.76e-06	2	84	2	14550562
Pubmed	Loss of SPEG Inhibitory Phosphorylation of Ryanodine Receptor Type-2 Promotes Atrial Fibrillation.	SPEG RYR2	5.76e-06	2	84	2	32683896
Pubmed	MSI1 Stabilizes MACF1 to Inhibit Apoptosis of MC3T3-E1 Cells Induced by High Glucose and Promote Osteogenic Differentiation Through Wnt/β-Catenin Signaling Pathway.	MACF1 MSI1	5.76e-06	2	84	2	36443618
Pubmed	Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.	RYR2 RYR3	5.76e-06	2	84	2	14985349
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	DST MATR3 MACF1 KIF3C ZFC3H1	1.12e-05	120	84	5	31413325
Pubmed	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	ZNF469 GNL2 ARHGAP18 CDCA8	1.22e-05	58	84	4	24144296
Pubmed	Genome-Wide CRISPR-Cas9 Screen Reveals Selective Vulnerability of ATRX-Mutant Cancers to WEE1 Inhibition.	PKMYT1 SMC6 CDCA8 RBM39	1.30e-05	59	84	4	31551363
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	KMT2C WAPL DST MYO9A MACF1 RBM39 SVEP1	1.34e-05	322	84	7	26514267
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	SORBS2 DST MACF1	1.50e-05	20	84	3	21689717
Pubmed	PTPN23 binds the dynein adaptor BICD1 and is required for endocytic sorting of neurotrophin receptors.	BICD2 ANLN ARHGEF18	1.50e-05	20	84	3	32079660
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TRAF7 ZNF469 WAPL ZFHX4 ARHGAP10 RBL1 ZMYND8 GNL2 CUL9 MACF1 MSI1 MBD2	1.51e-05	1116	84	12	31753913
Pubmed	ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.	BICD2 RRP1B NOM1 ZMYND8 GNL2 MBD2 CDCA8	1.57e-05	330	84	7	33301849
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	SORBS2 DST CUL9 MACF1 PDZD2	1.65e-05	130	84	5	12421765
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	WAPL RRP1B ANLN SMC6 GNL2 BOP1 CHD2 BTAF1 CDCA8	1.65e-05	608	84	9	36089195
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR2 RYR3	1.73e-05	3	84	2	18403125
Pubmed	Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.	RYR2 RYR3	1.73e-05	3	84	2	18434746
Pubmed	Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.	RYR2 RYR3	1.73e-05	3	84	2	29730765
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	DST MACF1	1.73e-05	3	84	2	12399109
Pubmed	SPRY domains in ryanodine receptors (Ca(2+)-release channels).	RYR2 RYR3	1.73e-05	3	84	2	9204703
Pubmed	The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.	RYR2 RYR3	1.73e-05	3	84	2	7876312
Pubmed	Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.	RYR2 RYR3	1.73e-05	3	84	2	21881589
Pubmed	Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).	RYR2 RYR3	1.73e-05	3	84	2	12213830
Pubmed	Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.	RYR2 RYR3	1.73e-05	3	84	2	9242641
Pubmed	Mutation screening of PDZD2, GOLPH3, and MTMR12 genes in patients with schizophrenia.	MTMR12 PDZD2	1.73e-05	3	84	2	21451436
Pubmed	Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.	RYR2 RYR3	1.73e-05	3	84	2	22948152
Pubmed	Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.	RYR2 RYR3	1.73e-05	3	84	2	10788707
Pubmed	RYR2 proteins contribute to the formation of Ca(2+) sparks in smooth muscle.	RYR2 RYR3	1.73e-05	3	84	2	15024040
Pubmed	Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.	RYR2 RYR3	1.73e-05	3	84	2	25239916
Pubmed	Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.	RYR2 RYR3	1.73e-05	3	84	2	7621815
Pubmed	A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.	RYR2 RYR3	1.73e-05	3	84	2	18643873
Pubmed	Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).	RYR2 RYR3	1.73e-05	3	84	2	11159936
Pubmed	Involvement of palladin and alpha-actinin in targeting of the Abl/Arg kinase adaptor ArgBP2 to the actin cytoskeleton.	SORBS2 PALLD	1.73e-05	3	84	2	16125169
Pubmed	Non-EST based prediction of exon skipping and intron retention events using Pfam information.	MYO9A CHD2	1.73e-05	3	84	2	16204458
Pubmed	Molecular identification of the ryanodine receptor pore-forming segment.	RYR2 RYR3	1.73e-05	3	84	2	10473538
Pubmed	Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.	RYR2 RYR3	1.73e-05	3	84	2	7959768
Pubmed	The organization of proteins in the human red blood cell membrane. A review.	RYR2 RYR3	1.73e-05	3	84	2	4600883
Pubmed	Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.	RYR2 RYR3	1.73e-05	3	84	2	7635066
Pubmed	Catalog of mRNA expression patterns for DNA methylating and demethylating genes in developing mouse lower urinary tract.	CHD2 MBD2 APOBEC3F	2.65e-05	24	84	3	23920106
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	KMT2C WAPL SPEG ZMYND8 GNL2 CHD2 RBM39 RYR3	2.77e-05	497	84	8	36774506
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	DST RRP1B PRRC2C GNL2 CUL9 MACF1 BOP1 CHD2 RBM39	2.89e-05	653	84	9	22586326
Pubmed	A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.	RYR2 RYR3	3.45e-05	4	84	2	18206662
Pubmed	Ryanodine receptor calcium release channels: lessons from structure-function studies.	RYR2 RYR3	3.45e-05	4	84	2	23413940
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST MACF1	3.45e-05	4	84	2	8954775
Pubmed	Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.	RYR2 RYR3	3.45e-05	4	84	2	9384575
Pubmed	Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.	RYR2 RYR3	3.45e-05	4	84	2	9607712
Pubmed	Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.	RYR2 RYR3	3.45e-05	4	84	2	23482488
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	DST PRRC2C MATR3 GNL2 MSI1 RBM39	3.94e-05	258	84	6	37794589
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CYLC1 SCN11A DST PRRC2C MATR3 MACF1 CHD2 FNBP1L ZFC3H1 CCDC77 PLIN1 PRX RYR2	4.09e-05	1442	84	13	35575683
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KMT2C WAPL DST RRP1B MATR3 SETBP1 AKNA BOP1	4.30e-05	529	84	8	14621295
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	RRP1B NOM1 MATR3 ZMYND8 BOP1 CHD2 MSI1 RBM39	4.54e-05	533	84	8	30554943
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KMT2C PTPN4 CPAMD8 MYO9A ARHGAP10 SETBP1 ARHGEF18 MACF1 CHD2 BTAF1 FNBP1L RBM39 PDZD2	5.68e-05	1489	84	13	28611215
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	RRP1B PRRC2C MATR3 GNL2 BOP1 MSI1 RBM39 TEFM APOBEC3F	5.69e-05	713	84	9	29802200
Pubmed	Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.	RYR2 RYR3	5.74e-05	5	84	2	33060591
Pubmed	Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.	RYR2 RYR3	5.74e-05	5	84	2	23918386
Pubmed	Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy.	KMT2C FGD5	5.74e-05	5	84	2	33596429
Pubmed	The HARP-like domain-containing protein AH2/ZRANB3 binds to PCNA and participates in cellular response to replication stress.	ZRANB3 RAD54L	5.74e-05	5	84	2	22705370
Pubmed	Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.	RYR2 RYR3	5.74e-05	5	84	2	19011160
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	PKMYT1 TOM1L2 DST RRP1B SYNM NOM1 MATR3 GNL2 BOP1 MSI1 CCDC77 RBM39 TEFM	5.96e-05	1496	84	13	32877691
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	BICD2 FRY ZBTB38 SORBS2 WAPL DST SYNM ZMYND8 CUL9 MACF1 ZFC3H1 RYR3	5.96e-05	1285	84	12	35914814
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	BICD2 PRRC2C NOM1 SMC6 MACF1 BOP1 FNBP1L ZFC3H1 PALLD	6.40e-05	724	84	9	36232890
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	ZFHX4 NOM1 ZMYND8 CUL9 MACF1 MBD2	6.45e-05	282	84	6	23667531
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PKMYT1 TRAF7 KMT2C SLC2A4RG DST SPEG AKNA CUL9 BTAF1 FHIP1B ANKRD33B	7.07e-05	1105	84	11	35748872
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	ZNF469 SETBP1 ZMYND8 ARHGEF18 PLEKHA7 ZRANB3 PRX	8.40e-05	430	84	7	35044719
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	WAPL DST PRRC2C MATR3 ZMYND8 GNL2 MACF1 BTAF1 PALLD RBM39	8.53e-05	934	84	10	33916271
Pubmed	Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.	AGPAT5 ANLN PRRC2C APOBEC3F	8.53e-05	95	84	4	24029230
Pubmed	Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.	RYR2 RYR3	8.59e-05	6	84	2	19549818
Pubmed	Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.	RYR2 RYR3	8.59e-05	6	84	2	26025922
Pubmed	Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.	RYR2 RYR3	8.59e-05	6	84	2	23463619
Pubmed	FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.	RYR2 RYR3	8.59e-05	6	84	2	14592808
Pubmed	A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.	RYR2 RYR3	8.59e-05	6	84	2	20519450
Pubmed	Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.	RYR2 RYR3	8.59e-05	6	84	2	25966694
Pubmed	HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.	RYR2 RYR3	8.59e-05	6	84	2	19009018
Pubmed	The LIM homeodomain transcription factor LHX6: a transcriptional repressor that interacts with pituitary homeobox 2 (PITX2) to regulate odontogenesis.	PITX2 LHX6	8.59e-05	6	84	2	23229549
Pubmed	E2F and histone deacetylase mediate transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest.	RBL1 CDC25A	8.59e-05	6	84	2	9858615
Pubmed	IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.	RYR2 RYR3	8.59e-05	6	84	2	16844763
Pubmed	Functional proteomics mapping of a human signaling pathway.	TOM1L2 UBXN11 DST NOM1 ZMYND8 MACF1 SVEP1 RYR2	9.31e-05	591	84	8	15231748
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	WAPL RRP1B ANLN PRRC2C MATR3 SMC6 ZMYND8 GNL2 CDCA8 RBM39	1.01e-04	954	84	10	36373674
Pubmed	A comprehensive resource of interacting protein regions for refining human transcription factor networks.	NOM1 MATR3 ZFC3H1 RYR2 RYR3	1.03e-04	191	84	5	20195357
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	MTMR12 SORBS2 DST RASSF8 CCDC77 PLEKHA7 KIAA0753	1.05e-04	446	84	7	24255178
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	RRP1B PRRC2C NOM1 MATR3 GNL2 BOP1 CHD2 MSI1 CCDC77 MBD2 TEFM APOBEC3F	1.10e-04	1371	84	12	36244648
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	RRP1B PRRC2C SPEG MATR3 PITX2 GNL2 BTAF1 MSI1 CDC25A RBM39	1.17e-04	971	84	10	33306668
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	DST NEXMIF ARHGEF18 MACF1 RYR2	1.19e-04	197	84	5	20811636
Interaction	YWHAQ interactions	PTPN4 MTMR12 ZBTB38 SORBS2 DST MYO9A ARHGAP10 ANLN SPEG MATR3 MAP3K9 MOB3C MACF1 FGD5 RASSF8 CDC25A PLEKHA7 RBM39	6.29e-07	1118	84	18	int:YWHAQ
Interaction	NUP43 interactions	BICD2 DST RRP1B PRRC2C ZMYND8 GNL2 BOP1 ZFC3H1 CDCA8 RBM39 RYR2 PDZD2 AFG1L	1.80e-06	625	84	13	int:NUP43
Interaction	SRPK2 interactions	ZFHX4 RRP1B ANLN PRRC2C NOM1 MATR3 GNL2 MACF1 BOP1 CHD2 ZFC3H1 PALLD RBM39	8.01e-06	717	84	13	int:SRPK2
Interaction	YWHAH interactions	PTPN4 MTMR12 SORBS2 DST MYO9A ANLN PRRC2C SPEG MATR3 MAP3K9 MACF1 RASSF8 CDC25A PLEKHA7 PALLD KIAA0753	1.09e-05	1102	84	16	int:YWHAH
Interaction	TJP2 interactions	BICD2 ANLN MATR3 GNL2 FGD5 FNBP1L RASSF8 RBM39	2.69e-05	288	84	8	int:TJP2
Interaction	CORO1A interactions	BICD2 TRAF7 SORBS2 ANLN PALMD RASSF8	2.85e-05	142	84	6	int:CORO1A
Interaction	SFN interactions	MTMR12 SORBS2 DST MYO9A ANLN PRRC2C MATR3 MACF1 CDC25A PLEKHA7 PALLD RBM39	2.87e-05	692	84	12	int:SFN
Interaction	MAGED2 interactions	ZBTB38 EID3 ANLN NOM1 MAP3K9 MOB3C RBM39	6.99e-05	243	84	7	int:MAGED2
Interaction	H3C1 interactions	KMT2C WAPL RRP1B ARHGAP10 ANLN PRRC2C SMC6 ZMYND8 GNL2 MBD2 CDCA8 PALLD PDZD2	8.62e-05	901	84	13	int:H3C1
Interaction	MYL6B interactions	MYO9A ANLN FGD5 FHIP1B RBM39	8.88e-05	108	84	5	int:MYL6B
Interaction	YWHAZ interactions	PTPN4 MTMR12 SORBS2 DST MYO9A ANLN SPEG MATR3 MAP3K9 MOB3C ARHGEF18 MACF1 RASSF8 CDC25A PLEKHA7 RBM39	9.57e-05	1319	84	16	int:YWHAZ
Interaction	H2BC9 interactions	CYLC1 BICD2 ZNF469 DST ZFHX4 SETBP1 CUL9 CDC25A PALLD	9.96e-05	446	84	9	int:H2BC9
Interaction	ZBTB2 interactions	BICD2 RRP1B NOM1 ZMYND8 GNL2 RASSF8 ARHGAP18 MBD2 CDCA8	1.07e-04	450	84	9	int:ZBTB2
Interaction	RALY interactions	TRAF7 RRP1B ANLN MATR3 CUL9 ZFC3H1 RBM39 APOBEC3F	1.19e-04	356	84	8	int:RALY
Interaction	ATRX interactions	PKMYT1 PTPN4 ZFHX4 SMC6 ZMYND8 CDCA8 RBM39	1.26e-04	267	84	7	int:ATRX
Interaction	CSNK2A1 interactions	PTPN4 DST RRP1B ANLN RBL1 PRRC2C ZMYND8 CUL9 MACF1 BOP1 ZFC3H1 ARHGAP18 RBM39	1.56e-04	956	84	13	int:CSNK2A1
Cytoband	15q26	CHD2 PLIN1	3.90e-04	16	84	2	15q26
Cytoband	Ensembl 112 genes in cytogenetic band chr15q26	LINS1 SYNM CHD2 PLIN1	5.74e-04	206	84	4	chr15q26
Cytoband	5p13.3	MTMR12 PDZD2	8.89e-04	24	84	2	5p13.3
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR2 RYR3	3.03e-05	3	58	2	287
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	2.80e-04	8	58	2	939
Coexpression	CUI_TCF21_TARGETS_2_DN	BICD2 KMT2C FRY ZBTB38 DST SPEG ARHGEF18 MACF1 FGD5 BTAF1 ANKRD33B PALLD PRX	2.74e-06	854	83	13	M1533
Coexpression	CUI_TCF21_TARGETS_2_DN	BICD2 KMT2C FRY ZBTB38 DST SPEG ARHGEF18 MACF1 FGD5 BTAF1 ANKRD33B PALLD PRX	4.19e-06	888	83	13	MM1018
Coexpression	LAKE_ADULT_KIDNEY_C29_UNKNOWN_NOVEL_PT_CFH_POS_SUBPOPULATION_S2	DST MYO9A MACF1 PLEKHA7 PALLD	8.03e-06	86	83	5	M39248
Coexpression	KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP	PKMYT1 RRP1B ANLN NEXMIF NOM1 MATR3 SMC6 GNL2 AKNA BOP1 CDC25A CDCA8 ZRANB3 RAD54L TEFM	1.15e-05	1290	83	15	M80
Coexpression	GSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN	BICD2 FRY MACF1 CCDC77 HELQ AFG1L	1.49e-05	166	83	6	M6826
Coexpression	LE_NEURONAL_DIFFERENTIATION_DN	PKMYT1 MSI1 LHX6	2.86e-05	19	83	3	M2441
Coexpression	BLANCO_MELO_BRONCHIAL_EPITHELIAL_CELLS_INFLUENZA_A_DEL_NS1_INFECTION_DN	PKMYT1 ANLN RBL1 CDC25A CDCA8 RAD54L	2.91e-05	187	83	6	M34027
Coexpression	HALLMARK_MITOTIC_SPINDLE	SORBS2 DST ARHGAP10 ANLN KIF3C PALLD	4.12e-05	199	83	6	M5893
Coexpression	GSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP	BICD2 FRY RBL1 SMC6 KIF3C FNBP1L	4.24e-05	200	83	6	M9205
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	WAPL DST RRP1B ZMYND8 FNBP1L ZFC3H1 MBD2	4.74e-05	300	83	7	M8702
Coexpression	LAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM	SORBS2 ARHGAP10 PRRC2C CHD2 ZFC3H1 PLEKHA7 RBM39 PDZD2	5.34e-05	417	83	8	M39224
Coexpression	LAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_SMALL_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP	PKMYT1 AGPAT5 ANLN RBL1 NEXMIF CDC25A HELQ CDCA8 ZRANB3 RAD54L	5.72e-05	680	83	10	MM456
Coexpression	LAKE_ADULT_KIDNEY_C2_PODOCYTES	FRY DST MACF1 RASSF8 PALLD RYR3	5.86e-05	212	83	6	M39221
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	BICD2 KMT2C PTPN4 ZBTB38 WAPL SLC2A4RG MATR3 AKNA MACF1 CHD2 BTAF1 ZFC3H1 MBD2 RBM39 APOBEC3F	6.22e-05	1492	83	15	M40023
Coexpression	HOWARD_NK_CELL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_3DY_UP	PKMYT1 ANLN CDC25A CDCA8	6.52e-05	68	83	4	M41108
Coexpression	LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2	ZBTB38 SORBS2 PRRC2C SETBP1 PLEKHA7 PDZD2	7.38e-05	221	83	6	M39222
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP	PKMYT1 RRP1B RBL1 ARHGAP18 CCDC77 CDCA8 PALLD ZRANB3 RAD54L	8.94e-05	578	83	9	M2368
Coexpression	MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3	SYNM SLC24A2 PITX2 MAP3K9 ANKRD33B	9.29e-05	143	83	5	M1935
Coexpression	MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3	SYNM SLC24A2 PITX2 MAP3K9 ANKRD33B	9.29e-05	143	83	5	MM819
Coexpression	DAZARD_UV_RESPONSE_CLUSTER_G6	WAPL RRP1B ZMYND8 FNBP1L MBD2	9.92e-05	145	83	5	M1810
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP	PKMYT1 RRP1B RBL1 ARHGAP18 CCDC77 CDCA8 PALLD ZRANB3 RAD54L	1.14e-04	597	83	9	MM1309
Coexpression	LAKE_ADULT_KIDNEY_C28_INTERSTITIUM	DST ARHGAP10 SETBP1 PALLD	1.63e-04	86	83	4	M39247
Coexpression	GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_DN	PRRC2C SETBP1 GNL2 ZFC3H1 RBM39	1.87e-04	166	83	5	M8129
Coexpression	GSE7768_OVA_ALONE_VS_OVA_WITH_LPS_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP	ZBTB38 ZMYND8 MAP3K9 CUL9 HELQ	2.03e-04	169	83	5	M6851
Coexpression	VILLANUEVA_LIVER_CANCER_KRT19_UP	RRP1B ANLN CDC25A CDCA8 RAD54L	2.39e-04	175	83	5	M336
Coexpression	GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP	DST ANLN SETBP1 CDCA8 RAD54L	2.45e-04	176	83	5	M2981
Coexpression	HOEBEKE_LYMPHOID_STEM_CELL_UP	SETBP1 MACF1 PALLD RBM39	2.59e-04	97	83	4	M14698
Coexpression	LAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_LARGE_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP	PKMYT1 EID3 ANLN CDC25A CDCA8 ZRANB3 RAD54L	2.89e-04	402	83	7	MM454
ToppCell	droplet-Fat-Mat-18m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRY SORBS2 DST SYNM FGD5 PALMD LHX6 RYR2	3.27e-09	193	84	8	54024a373e42e1c0bcc327dc084564b83b63a9d4
ToppCell	droplet-Fat-Mat-18m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRY SORBS2 DST SYNM FGD5 PALMD LHX6 RYR2	3.27e-09	193	84	8	81d908594d2983ba7e7c1ec25afdde4315d9690e
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	FRY SORBS2 DST PALMD PALLD RYR2 PDZD2	5.93e-08	184	84	7	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	CPAMD8 SORBS2 SETBP1 PALMD ANKRD33B PALLD PDZD2	7.65e-08	191	84	7	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	droplet-Fat-Mat-18m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORBS2 DST SYNM FGD5 PALMD LHX6 RYR2	8.51e-08	194	84	7	74d0eaa76f6d9af14110dfe5b4bf9751b99ff6e3
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PRRC2C AKNA MACF1 CHD2 BTAF1 ZFC3H1 RBM39	1.01e-07	199	84	7	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KMT2C PRRC2C MACF1 CHD2 BTAF1 ZFC3H1 RBM39	1.05e-07	200	84	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CPAMD8 ZFHX4 SLC24A2 SPEG PLIN1 RYR3	1.60e-07	128	84	6	2cf0384240a4a663869cf6b27d954236f6214a9a
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPEG KIF3C PALMD PLIN1 LHX6 RYR3	4.76e-07	154	84	6	16fdafb5c64d2db321554f87129a962d113f1668
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	PRRC2C AKNA MACF1 CHD2 BTAF1 RBM39	8.78e-07	171	84	6	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB38 MYO9A PRRC2C MATR3 MACF1 RYR2	1.04e-06	176	84	6	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	10x5'-blood-Lymphocytic_NK-Cycling_NK\|blood / Manually curated celltypes from each tissue	PKMYT1 ANLN TMEM132E CDC25A CDCA8 RAD54L	1.15e-06	179	84	6	c93711273055a999335ba8d0f6500e4549f46cec
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5\|TCGA-Liver / Sample_Type by Project: Shred V9	PKMYT1 EID3 ANLN RBL1 CDCA8 RAD54L	1.30e-06	183	84	6	f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	SORBS2 DST MACF1 ANKRD33B SVEP1 RYR2	1.35e-06	184	84	6	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	FRY SORBS2 PALMD PALLD RYR2 PDZD2	1.39e-06	185	84	6	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	368C-Myeloid-Dendritic-cDC_proliferating_1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ANLN RBL1 FNBP1L CDC25A CDCA8 AFG1L	1.43e-06	186	84	6	799903b68bc6f6205d004b44c603424b0d5f7c32
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCN11A FRY PIK3R6 FGD5 PALMD LHX6	1.43e-06	186	84	6	055cc23c4db9aad2d6c62e62c8e58bfe5047c6b1
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	FRY DST SPEG SETBP1 PALLD RYR2	1.48e-06	187	84	6	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	DST SETBP1 MACF1 PALLD SVEP1 RYR2	1.48e-06	187	84	6	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	DST ARHGAP10 SETBP1 PALLD SVEP1 RYR2	1.48e-06	187	84	6	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN4 FRY MYO9A SETBP1 ZMYND8 PLEKHA7	1.57e-06	189	84	6	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRY SYNM PALMD PALLD RYR2 PDZD2	1.62e-06	190	84	6	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	DST ARHGAP10 SETBP1 PALLD SVEP1 RYR2	1.62e-06	190	84	6	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BICD2 PTPN4 FRY FNBP1L ANKRD33B PRX	1.67e-06	191	84	6	df8cdbc26443e55a203cbafa21b0952a2a55b9bf
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DST SETBP1 MACF1 PALLD SVEP1 RYR2	1.67e-06	191	84	6	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DST SETBP1 MACF1 PALLD SVEP1 RYR2	1.72e-06	192	84	6	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DST SETBP1 MACF1 PALLD SVEP1 RYR2	1.77e-06	193	84	6	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DST SETBP1 MACF1 PALLD SVEP1 RYR2	1.77e-06	193	84	6	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ANLN RBL1 CCDC77 CDCA8 ZRANB3 RAD54L	1.77e-06	193	84	6	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DST SETBP1 MACF1 PALLD SVEP1 RYR2	1.94e-06	196	84	6	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DST SETBP1 MACF1 PALLD SVEP1 RYR2	2.00e-06	197	84	6	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRY SYNM ARHGAP10 SPEG PALLD RYR2	2.00e-06	197	84	6	bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KMT2C PRRC2C MACF1 BTAF1 ZFC3H1 RBM39	2.00e-06	197	84	6	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FRY SORBS2 SYNM ARHGAP10 PALLD RYR2	2.00e-06	197	84	6	d16bb765afdc02406ffd7ce6a75bae72b66db66c
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FRY SORBS2 SYNM ARHGAP10 PALLD RYR2	2.00e-06	197	84	6	68c23c23b6924892f4c238cf2f5abc7927e04fbc
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DST SETBP1 MACF1 PALLD SVEP1 RYR2	2.06e-06	198	84	6	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PKMYT1 ANLN RBL1 MSI1 CCDC77 RAD54L	2.06e-06	198	84	6	d5e125f0c4f41b47d567568d0838adcca7655f6d
ToppCell	Biopsy_Control_(H.)-Epithelial-Proliferating_Epithelial_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	PKMYT1 SLC2A4RG ANLN CDC25A CDCA8 RAD54L	2.12e-06	199	84	6	4fcf5bec207e4384fd73c5e8801a7e414e3ee7b0
ToppCell	mild-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PTPN4 ZBTB38 PRRC2C AKNA MACF1 RBM39	2.18e-06	200	84	6	d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	DST SETBP1 MACF1 PALLD SVEP1 RYR2	2.18e-06	200	84	6	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DST SETBP1 MACF1 PALLD SVEP1 RYR2	2.18e-06	200	84	6	a510deaada669e690329183e18df02870bd204b3
ToppCell	mild-T/NK_proliferative\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PKMYT1 ANLN RBL1 CDC25A CDCA8 RAD54L	2.18e-06	200	84	6	25b4a1a33348e274bd4457efc0d6faa5421c3d31
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PKMYT1 ANLN RBL1 CDC25A CDCA8 RAD54L	2.18e-06	200	84	6	af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCell	mild-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PKMYT1 ANLN RBL1 CDC25A CDCA8 RAD54L	2.18e-06	200	84	6	63cc57b9331459efbb73051d174d198a3568b938
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DST SETBP1 MACF1 PALLD SVEP1 RYR2	2.18e-06	200	84	6	dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCell	RA-06._Ventricular_Cardiomyocyte_II\|RA / Chamber and Cluster_Paper	SCN11A SORBS2 PALLD RYR2 PDZD2	5.16e-06	132	84	5	82674ec4b0a416e4f08372b86c2a475afe3f38a5
ToppCell	LPS-antiTNF-Unknown-Endothelial-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANLN CDCA8 RYR2 RAD54L RYR3	5.16e-06	132	84	5	02491930097b75aaeedab9e8200711b0dc610944
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANLN PALMD PLIN1 LHX6 RYR3	5.16e-06	132	84	5	46c80eab16a70da9f363a9fbdf50bccab0b287d7
ToppCell	LPS-IL1RA+antiTNF-Unknown\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANLN PALMD PLIN1 LHX6 RYR3	5.16e-06	132	84	5	a022c3c41654166cb106f27dc54fa88e8c40f898
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	PRRC2C MACF1 CHD2 BTAF1 RBM39	5.76e-06	135	84	5	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	AKNA MACF1 CHD2 BTAF1 RBM39	8.72e-06	147	84	5	94998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCell	10x5'-bone_marrow-Lymphocytic_B-GC_B_(I)\|bone_marrow / Manually curated celltypes from each tissue	PKMYT1 ANLN CDC25A CDCA8 RAD54L	1.20e-05	157	84	5	d4da4057917dda066da0f2aac2621fdaf1fb943b
ToppCell	COPD-Lymphoid-ILC_B\|Lymphoid / Disease state, Lineage and Cell class	FRY DST AGPAT5 ARHGAP10 RASSF8	1.57e-05	166	84	5	e2cad1db536d5ad5a34c337c19b5e7d1a2851552
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D122\|Adult / Lineage, Cell type, age group and donor	CPAMD8 SPEG FGD5 PALMD RYR3	1.66e-05	168	84	5	8c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRY SORBS2 PALMD PALLD RYR2	1.76e-05	170	84	5	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	PKMYT1 ANLN MAP3K9 CDC25A CDCA8	1.81e-05	171	84	5	4ede6e916e593f208f2f8ccf82ef2335e061fc86
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ANLN ZNF772 FNBP1L CDCA8 RAD54L	1.81e-05	171	84	5	0eea035fde32cc2a75a0d4227911edb5d54ed47e
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST MYO9A PRRC2C MACF1 ZFC3H1	1.92e-05	173	84	5	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST MYO9A PRRC2C MACF1 ZFC3H1	1.92e-05	173	84	5	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST MYO9A PRRC2C MACF1 ZFC3H1	1.92e-05	173	84	5	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Cycling_T\|GI_small-bowel / Manually curated celltypes from each tissue	PKMYT1 ANLN CDC25A CDCA8 RAD54L	1.97e-05	174	84	5	e4c8da80eca07e4396f57dad212f76c2eca4c1bd
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PKMYT1 ANLN CDC25A CDCA8 RAD54L	2.02e-05	175	84	5	a6913f992a1ea20b43e5adeca3ede3a6fda820ad
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SORBS2 ANLN PALMD LHX6 CDCA8	2.02e-05	175	84	5	d43ae33a6256606ce848247cad32d74f21b38988
ToppCell	severe_influenza-Plasmablast\|World / disease group, cell group and cell class (v2)	PKMYT1 SORBS2 ANLN CDCA8 RAD54L	2.02e-05	175	84	5	e6d6c44510d5dc4eb0bae820125e42366f7a4e74
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PKMYT1 ANLN MSI1 CCDC77 CDCA8	2.02e-05	175	84	5	a154b28b0b2180652d51d4c7d804b3b81b35899e
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST MYO9A PRRC2C MACF1 ZFC3H1	2.02e-05	175	84	5	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	10x5'-blood-Lymphocytic_B_plasma-Plasmablasts\|blood / Manually curated celltypes from each tissue	PKMYT1 ANLN CDC25A CDCA8 RAD54L	2.02e-05	175	84	5	2e048bf7961c3d86b6e12a1ebae3b3f2359af457
ToppCell	368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	PKMYT1 ANLN CDC25A CDCA8 RAD54L	2.02e-05	175	84	5	74800a10f5ff25d5414fbccb0668f92ff077d1cc
ToppCell	368C-Myeloid-Dendritic-cDC_proliferating_1\|368C / Donor, Lineage, Cell class and subclass (all cells)	ANLN RBL1 CDC25A CDCA8 AFG1L	2.26e-05	179	84	5	ec69e1dd897414033ba5b007aa82655a79adca6c
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF469 ARHGAP10 PALMD ANKRD33B PDZD2	2.26e-05	179	84	5	9ba8693fba2175bca9ff9735cc04e657abeb9084
ToppCell	droplet-Limb_Muscle-Pre-Sort\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORBS2 DST SPEG PALLD RYR2	2.32e-05	180	84	5	af2bafcd1b2082629de3ea336711add01565c4c4
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORBS2 DST SPEG PALLD RYR2	2.32e-05	180	84	5	f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCell	IIH-cycling-\|IIH / Condition, Cell_class and T cell subcluster	PKMYT1 ANLN CDC25A CDCA8 RAD54L	2.38e-05	181	84	5	7f4fed9e296bc22cb5a1e6c8e3c4b641e97c3078
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRY SORBS2 PALMD PALLD RYR2	2.38e-05	181	84	5	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	IIH-cycling\|IIH / Condition, Cell_class and T cell subcluster	PKMYT1 ANLN CDC25A CDCA8 RAD54L	2.38e-05	181	84	5	ec3e782ce93dcfe1a54fb7284e4e39063614b0e2
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating-Lymphatic_EC_proliferating_L.2.5.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PKMYT1 ANLN KIF3C CDCA8 RAD54L	2.44e-05	182	84	5	f703963b5d1e8c1f95d78807521048553b0792d8
ToppCell	PBMC-Control-cDC_12\|Control / Compartment, Disease Groups and Clusters	PKMYT1 SLC2A4RG RBL1 CDC25A RAD54L	2.44e-05	182	84	5	4774066d0f9986abc3d13a2a3bc99ce4f1327ae0
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_A\|E18.5-samps / Age Group, Lineage, Cell class and subclass	ANLN FGD5 PALMD ARHGAP18 PRX	2.44e-05	182	84	5	ea4f6c8f600ffe9f8e0609637b3371a5ac48ca03
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial\|E18.5-samps / Age Group, Lineage, Cell class and subclass	FGD5 PALMD ARHGAP18 PRX RYR2	2.44e-05	182	84	5	7af3b2029b7f55b923d5a4b764d4292f4ea48599
ToppCell	droplet-Spleen-nan-18m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C SMC6 MACF1 CHD2 RBM39	2.44e-05	182	84	5	eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	PIK3R6 FGD5 PALMD PRX RYR2	2.44e-05	182	84	5	fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCell	E18.5-samps-Endothelial\|E18.5-samps / Age Group, Lineage, Cell class and subclass	FGD5 PALMD ARHGAP18 PRX RYR2	2.44e-05	182	84	5	e2d799e6e7526176a6fe6515b8fbe4d83d3a3ea1
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANLN RBL1 CCDC77 CDCA8 KIAA0753	2.44e-05	182	84	5	0fc45214f0b0766f69be6eff69cc4bec574023aa
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PKMYT1 ANLN KIF3C CDCA8 RAD54L	2.44e-05	182	84	5	ebd177ad5eac51bf2db0657596618bdf1e5d46e1
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF469 SORBS2 ARHGAP10 PALMD PDZD2	2.51e-05	183	84	5	1645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCell	IPF-Lymphoid-ILC_B\|Lymphoid / Disease state, Lineage and Cell class	FRY DST AGPAT5 ARHGAP10 RASSF8	2.51e-05	183	84	5	9b507547e6adf78e46e7f542cd9958224ec5826a
ToppCell	IIF-Lymphocyte-T_NK-T_NK_proliferative\|IIF / Disease, Lineage and Cell Type	PKMYT1 ANLN CDC25A CDCA8 RAD54L	2.57e-05	184	84	5	ab8b45ce40e8c5f66e5c23332a591b4f9cba4ce1
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF469 SORBS2 ARHGAP10 PALMD PDZD2	2.57e-05	184	84	5	34e316ad8e7b8667cd8ad61397281802a252744f
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	CPAMD8 FGD5 PALMD ANKRD33B PDZD2	2.57e-05	184	84	5	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRY SORBS2 PALMD PALLD RYR2	2.64e-05	185	84	5	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	PKMYT1 ANLN RBL1 CDCA8 RAD54L	2.64e-05	185	84	5	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	Adult-Endothelial-endothelial_cell_of_artery\|Adult / Lineage, Cell type, age group and donor	CPAMD8 SETBP1 FGD5 PALMD RYR3	2.71e-05	186	84	5	2d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	KMT2C MACF1 CHD2 BTAF1 RBM39	2.85e-05	188	84	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	10x5'-Liver-Lymphocytic_NK-Cycling_NK\|Liver / Manually curated celltypes from each tissue	PKMYT1 ANLN CDC25A CDCA8 RAD54L	2.85e-05	188	84	5	5eb94e652a734c6f15c68a178e9d05f0febcf34c
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	FRY ARHGAP10 MACF1 RYR2 RYR3	2.85e-05	188	84	5	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C CHD2 PALMD PALLD RBM39	2.85e-05	188	84	5	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-T_NK_proliferative\|Multiple_Sclerosis / Disease, Lineage and Cell Type	PKMYT1 ANLN CDC25A CDCA8 RAD54L	2.85e-05	188	84	5	6c05797a5d0635d89ffcf4aca52178687129ccb4
ToppCell	3'-Adult-Distal_Rectal-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 SYNM ARHGAP10 PALLD RYR2	2.93e-05	189	84	5	d69b7a01dd4d6ad043bb6210e9ab34b49578389c
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BICD2 PTPN4 FRY FNBP1L PRX	2.93e-05	189	84	5	09dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCell	5'-Adult-Appendix-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FRY SORBS2 SYNM PALLD RYR2	2.93e-05	189	84	5	0daa8efac08dca9525d2b8d421952068cab4eb50
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KMT2C ZBTB38 DST PRRC2C	6.40e-05	49	48	4	GAVISH_3CA_MALIGNANT_METAPROGRAM_41_UNASSIGNED
Drug	triphenylene	SYNM ANLN MBD2	7.82e-06	11	84	3	CID000009170
Drug	NMBzA	PTPN4 SYNM SETBP1 MBD2	1.73e-05	42	84	4	CID000013643
Drug	NMBA	SYNM ANLN SETBP1 MBD2	2.09e-05	44	84	4	CID000023471
Drug	2-hydroxycarbazole	RYR2 RYR3	4.03e-05	3	84	2	CID000093551
Drug	bromochloroacetonitrile	SYNM MBD2	4.03e-05	3	84	2	CID000055004
Drug	cis-diammineplatinum(II	RYR2 RYR3	4.03e-05	3	84	2	CID000159790
Drug	2-hydroxyheptanoic acid	RYR2 RYR3	4.03e-05	3	84	2	CID002750949
Drug	Ryanodyl 3-(pyridine-3-carboxylate	RYR2 RYR3	4.03e-05	3	84	2	CID005748312
Drug	8N3-cADPR	RYR2 RYR3	4.03e-05	3	84	2	CID000127713
Drug	tetrabenzonaphthalene	SYNM MBD2	4.03e-05	3	84	2	CID000067449
Drug	aminodantrolene	RYR2 RYR3	4.03e-05	3	84	2	CID009570289
Drug	DB08375	PTPN4 SYNM MBD2	6.14e-05	21	84	3	CID006323466
Drug	AC1L1CR9	UBXN11 RBL1 RYR3	6.14e-05	21	84	3	CID000002023
Drug	MS-275; Down 200; 10uM; PC3; HT_HG-U133A	BICD2 WAPL CDC25A CDCA8 RAD54L KIAA0753	7.18e-05	189	84	6	7074_DN
Drug	iminodiacetonitrile	SYNM MBD2	8.03e-05	4	84	2	CID000069413
Drug	(dimethylamino)acetonitrile	SYNM MBD2	8.03e-05	4	84	2	CID000061237
Drug	PCB74	RYR2 RYR3	8.03e-05	4	84	2	CID000036218
Drug	3-indolylacetone	SYNM MBD2	8.03e-05	4	84	2	CID000070989
Drug	148504-47-6	RYR2 RYR3	8.03e-05	4	84	2	CID006444275
Drug	SC 38249	RYR2 RYR3	8.03e-05	4	84	2	CID000134834
Drug	dimethyl phosphite	DST MBD2	8.03e-05	4	84	2	CID006327114
Drug	O4-methylthymidine	PTPN4 SYNM	8.03e-05	4	84	2	CID000073316
Drug	nitrilotriacetonitrile	SYNM MBD2	8.03e-05	4	84	2	CID000081762
Drug	ovalene	SYNM MBD2	8.03e-05	4	84	2	CID000067446
Drug	AC1L1U7A	RYR2 RYR3	8.03e-05	4	84	2	CID000035682
Drug	Harmol hydrochloride monohydrate [40580-83-4]; Up 200; 15.8uM; HL60; HG-U133A	FRY RRP1B ZMYND8 MAP3K9 KIF3C CDC25A	9.02e-05	197	84	6	1750_UP
Drug	Noscapine [128-62-1]; Down 200; 9.6uM; PC3; HT_HG-U133A	BICD2 RRP1B MYO9A SPEG CUL9 RASSF8	9.02e-05	197	84	6	5851_DN
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR2 RYR3	2.28e-05	3	82	2	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR2 RYR3	2.28e-05	3	82	2	DOID:8545 (implicated_via_orthology)
Disease	hereditary sensory neuropathy (implicated_via_orthology)	SCN11A DST	7.59e-05	5	82	2	DOID:0050548 (implicated_via_orthology)
Disease	Neurodevelopmental Disorders	KMT2C NEXMIF SETBP1 CHD2	1.34e-04	93	82	4	C1535926
Disease	advanced glycation end-product measurement, type 2 diabetes mellitus	ZBTB38 PALLD	2.11e-04	8	82	2	EFO_0007819, MONDO_0005148
Disease	Anterior segment dysgenesis	CPAMD8 PITX2	2.11e-04	8	82	2	cv:C1862839
Disease	atrial fibrillation	ZFHX4 SLC24A2 ARHGAP10 PITX2 KIF3C PALMD	5.95e-04	371	82	6	EFO_0000275
Disease	cortical surface area measurement	PKMYT1 BICD2 CPAMD8 ZNF469 PRRC2C CUL9 MACF1 FNBP1L PLEKHA7 SVEP1 PDZD2	1.22e-03	1345	82	11	EFO_0010736
Disease	blood arsenic measurement	SORBS2 FGD5	1.27e-03	19	82	2	EFO_0021527
Disease	Arthrogryposis	BICD2 MYO9A	1.55e-03	21	82	2	C0003886
Disease	cardiovascular disease	WAPL PITX2 ARHGEF18 FGD5 CDC25A SVEP1	1.73e-03	457	82	6	EFO_0000319
Disease	open-angle glaucoma	DST GNL2 PLEKHA7 SVEP1	2.01e-03	191	82	4	EFO_0004190
Disease	Agents acting on the renin-angiotensin system use measurement	PKMYT1 ARHGEF18 FGD5 CDC25A SVEP1	2.45e-03	335	82	5	EFO_0009931
Disease	upper face morphology measurement	SLC24A2 MACF1 PLEKHA7	2.53e-03	97	82	3	EFO_0010949
Disease	susceptibility to rheumatic fever measurement	CDC25A RYR3	2.75e-03	28	82	2	EFO_0008416

Protein segments in the cluster

Peptide	Gene	Start	Entry
GERKLSFLPRKFPSL	BOP1	336	Q14137
GSFKKKVSSTDPRPR	ARHGEF18	926	Q6ZSZ5
TRRGRAKAAPKTKPA	BICD2	806	Q8TD16
SPNRPDSSGKRSVKF	FAM219B	91	Q5XKK7
EGLFSKLFSRSKPPR	AFG1L	116	Q8WV93
AFKADPKISKRRPSR	CCDC77	191	Q9BR77
FQPERPARKGSTKDS	ANKRD33B	436	A6NCL7
KRREPKRKSLTFTGG	RASSF8	121	Q8NHQ8
RSKSPFRKDKSPVRE	RBM39	126	Q14498
KRAKVVERFNSPSSP	RAD54L	551	Q92698
KDRVFARSPSKPLAR	PTPN4	351	P29074
ADKPPESIRSRKARA	ARHGAP10	721	A1A4S6
SPFGSRTKKRSLLPE	FHIP1B	586	Q8N612
KPRLSPRETIFGKSE	PALMD	366	Q9NP74
ETTFGPKSQRKRPNL	GNL2	141	Q13823
TKRKFSPGRPRSKQG	KMT2C	831	Q8NEZ4
TSRDKKEFSLEPPSR	LINS1	666	Q8NG48
QERSLFEKKRGAPPS	MATR3	261	P43243
PLTQSKSSPKRGFFR	MTMR12	566	Q9C0I1
QFADSKKTPSRPGSR	DST	7481	Q03001
TSRSDESPKPGKFQR	ANLN	636	Q9NQW6
RFDSRVFKTPGLRTP	CDCA8	191	Q53HL2
RKSSRRKKAVSAPPG	KIF3C	406	O14782
VFGSFKLERSAPKPR	EID3	171	Q8N140
TRKFGVISRPPANKA	PDZD2	216	O15018
TFPKPLQRGTNDKSR	CYLC1	36	P35663
RDGKRKGVPFSRTVS	FGD5	726	Q6ZNL6
PKPAKRARTSFTAEQ	LHX6	216	Q9UPM6
DSKTIDPKVAFPRRA	MSI1	86	O43347
NRADPKKSASRPGSR	MACF1	7301	Q9UPN3
AVPREKPKRRVSDSF	PLIN1	486	O60240
KPKRRVSDSFFRPSV	PLIN1	491	O60240
VTPAGFPKKASRTAR	PALLD	876	Q8WX93
SPSGKKFRSKPQLAR	MBD2	181	Q9UBB5
TKGPSRPRLDAKIFR	APOBEC3F	41	Q8IUX4
EIKTGKPRIPSFRSL	FNBP1L	366	Q5T0N5
FAITSRRGPTPKAVK	BTAF1	981	O14981
KKPFRPEASGSSRDS	CHD2	1576	O14647
PPRTEKRKRTFFPET	CPAMD8	736	Q8IZJ3
FSKVGPRVRFPKDES	AKNA	361	Q7Z591
EPSTRPFSKNSKGRD	CUL9	1441	Q8IWT3
KKFGVIDRSSDPPRS	FRY	1986	Q5TBA9
AGSKGRFPPTKRREK	HELQ	416	Q8TDG4
GSAERTAQKRKFPSP	ZMYND8	11	Q9ULU4
ALTARKTKEFRSPPQ	RYR2	1956	Q92736
RSTSPPSRKLFKKEE	MAP3K9	806	P80192
FEFKKPVRPVSRGCL	CDC25A	146	P30304
KDKTFRPRKRFEPGT	MOB3C	11	Q70IA8
PKPLFFRRAKSSTAT	RRP1B	651	Q14684
DPASSPTSKRKRVKF	TMEM132E	1001	Q6IEE7
QVKTFPDRPKAGDTR	SYNM	441	O15061
TLPDVRKPSSRKFFP	SLC24A2	486	Q9UI40
GTPRKFTRDTPLGKL	RBL1	331	P28749
SFEVSFLPPARKRKS	NEXMIF	616	Q5QGS0
QDSKFPKDGFSPRRR	PIK3R6	566	Q5UE93
SSKATFPRPKSALER	PLEKHA7	1046	Q6IQ23
VLPPKREIAKRSFSS	PRRC2C	1531	Q9Y520
EKGRSQTSKLPPRFA	PRRC2C	1716	Q9Y520
PVSFRPGGRKSRKEL	NOM1	71	Q5C9Z4
PKTGREKRKSPENRF	TEFM	136	Q96QE5
PESRKEAASSKFFPR	PITX2	41	Q99697
KGERRPLTAKDTFPQ	KIAA0753	411	Q2KHM9
TKKASPFCRPGSVLR	SVEP1	981	Q4LDE5
SDFRKRRKSEPAVGP	SORBS2	251	O94875
EPKRTLPFRKGPNFT	ZFHX4	1471	Q86UP3
FIPSQAKPKASARRE	SPEG	1631	Q15772
HFLFGEPTLRKRKSP	SLC2A4RG	181	Q9NR83
SMSPFRGPKDRARKL	PKMYT1	141	Q99640
AALTARKTKEFRSPP	RYR3	1856	Q15413
SPVREKSPKFRFPRV	PRX	1401	Q9BXM0
DPRGCPFTIKLSARK	TRAF7	206	Q6Q0C0
KENTRKIFSGPKRSP	WAPL	536	Q7Z5K2
DSKTDRLKRFGPNVP	SMC6	471	Q96SB8
LPSFRLPKDKTGTTR	ARHGAP18	261	Q8N392
KDSPGERAKPRARST	ZNF469	3236	Q96JG9
RKSFFLRESGKDQPP	SCN11A	466	Q9UI33
PDKVGRFASRPKSIK	ZBTB38	761	Q8NAP3
PERRKRFPGKSVNSK	AGPAT5	301	Q9NUQ2
PSGRKKPERSEDALF	TOM1L2	491	Q6ZVM7
SPISREFPGTKKRKR	SETBP1	611	Q9Y6X0
FRRKADSLSSPRKNP	UHRF1BP1	426	Q6BDS2
REPSPPRKSSKSFGR	ZFC3H1	191	O60293
GEKPFRSDKSRPFLL	ZNF772	196	Q68DY9
PREVKGTRRKLPTAF	XRRA1	596	Q6P2D8
ARRAPKSSLKFSPGP	UBXN11	471	Q5T124
SRPRDPFTKKLLEDG	ZRANB3	861	Q5FWF4
PKDRPVTVFFERKGS	MYO9A	1596	B2RTY4