Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	plasma membrane proton-transporting V-type ATPase complex	ATP6V0D1 ATP6V0D2	7.83e-06	2	59	2	GO:0033181
GeneOntologyCellularComponent	plasma membrane protein complex	CACNA1S IGF1R ATP6V0D1 KCNJ2 SCN7A ATP6V0D2 C8A ITGA9 CDH17	3.31e-04	785	59	9	GO:0098797
GeneOntologyCellularComponent	proton-transporting V-type ATPase, V0 domain	ATP6V0D1 ATP6V0D2	5.08e-04	12	59	2	GO:0033179
GeneOntologyCellularComponent	protein complex involved in cell adhesion	LAMC1 PLAU ITGA9	6.21e-04	59	59	3	GO:0098636
GeneOntologyCellularComponent	protein complex involved in cell-matrix adhesion	LAMC1 PLAU	1.04e-03	17	59	2	GO:0098637
Domain	ATPase_V0-cplx_csu/dsu	ATP6V0D1 ATP6V0D2	9.48e-06	2	58	2	IPR002843
Domain	vATP-synt_AC39	ATP6V0D1 ATP6V0D2	9.48e-06	2	58	2	PF01992
Domain	ATPase_V0-cplx_dsu	ATP6V0D1 ATP6V0D2	9.48e-06	2	58	2	IPR016727
Domain	-	LAMC1 LAMC3 F5 EPHA8	7.77e-05	73	58	4	2.60.120.260
Domain	Galactose-bd-like	LAMC1 LAMC3 F5 EPHA8	2.07e-04	94	58	4	IPR008979
Domain	LAMININ_IVA	LAMC1 LAMC3	2.62e-04	8	58	2	PS51115
Domain	Laminin_B	LAMC1 LAMC3	2.62e-04	8	58	2	PF00052
Domain	LamB	LAMC1 LAMC3	2.62e-04	8	58	2	SM00281
Domain	Laminin_IV	LAMC1 LAMC3	2.62e-04	8	58	2	IPR000034
Domain	A2M_N	C3 PZP	4.20e-04	10	58	2	PF01835
Domain	A2M_N	C3 PZP	4.20e-04	10	58	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C3 PZP	4.20e-04	10	58	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C3 PZP	4.20e-04	10	58	2	PS00477
Domain	A2M	C3 PZP	4.20e-04	10	58	2	PF00207
Domain	A2M_N_2	C3 PZP	4.20e-04	10	58	2	IPR011625
Domain	A2M_comp	C3 PZP	4.20e-04	10	58	2	IPR011626
Domain	A2M_N_2	C3 PZP	4.20e-04	10	58	2	PF07703
Domain	A2M_recep	C3 PZP	4.20e-04	10	58	2	PF07677
Domain	A2M_comp	C3 PZP	4.20e-04	10	58	2	PF07678
Domain	Macroglobln_a2	C3 PZP	4.20e-04	10	58	2	IPR001599
Domain	Laminin_N	LAMC1 LAMC3	1.11e-03	16	58	2	IPR008211
Domain	LAMININ_NTER	LAMC1 LAMC3	1.11e-03	16	58	2	PS51117
Domain	Laminin_N	LAMC1 LAMC3	1.11e-03	16	58	2	PF00055
Domain	LamNT	LAMC1 LAMC3	1.11e-03	16	58	2	SM00136
Domain	EGF-like_CS	LAMC1 LAMC3 PLAU C8A EPHA8	1.28e-03	261	58	5	IPR013032
Domain	EGF_2	LAMC1 LAMC3 PLAU C8A EPHA8	1.37e-03	265	58	5	PS01186
Domain	Growth_fac_rcpt_	IGF1R LAMC1 LAMC3 C8A	1.40e-03	156	58	4	IPR009030
Domain	Terpenoid_cyclase/PrenylTrfase	C3 PZP	1.40e-03	18	58	2	IPR008930
Domain	EGF_LAM_2	LAMC1 LAMC3	3.90e-03	30	58	2	PS50027
Domain	EGF_LAM_1	LAMC1 LAMC3	3.90e-03	30	58	2	PS01248
Domain	KRAB	ZNF347 ZNF700 ZNF564 ZNF529 ZNF433	5.02e-03	358	58	5	PS50805
Domain	KRAB	ZNF347 ZNF700 ZNF564 ZNF529 ZNF433	5.02e-03	358	58	5	PF01352
Domain	Laminin_EGF	LAMC1 LAMC3	5.28e-03	35	58	2	PF00053
Domain	EGF_Lam	LAMC1 LAMC3	5.28e-03	35	58	2	SM00180
Domain	KRAB	ZNF347 ZNF700 ZNF564 ZNF529 ZNF433	5.70e-03	369	58	5	SM00349
Domain	KRAB	ZNF347 ZNF700 ZNF564 ZNF529 ZNF433	5.76e-03	370	58	5	IPR001909
Domain	Laminin_EGF	LAMC1 LAMC3	6.20e-03	38	58	2	IPR002049
Domain	EGF-like_dom	LAMC1 LAMC3 PLAU C8A	7.45e-03	249	58	4	IPR000742
Domain	EGF_1	LAMC1 LAMC3 PLAU C8A	8.09e-03	255	58	4	PS00022
Domain	-	REXO4 PIWIL3	9.37e-03	47	58	2	3.30.420.10
Pathway	KEGG_COMPLEMENT_AND_COAGULATION_CASCADES	C3 PLAU CD46 C8A F5	2.55e-06	69	45	5	M16894
Pathway	WP_COMPLEMENT_AND_COAGULATION_CASCADES	C3 PLAU CD46 F5	3.39e-05	58	45	4	M39649
Pathway	WP_DENGUE2_INTERACTIONS_WITH_COMPLEMENT_AND_COAGULATION_CASCADES	C3 PLAU CD46 F5	3.63e-05	59	45	4	M48343
Pathway	WP_COMPLEMENT_SYSTEM	LAMC1 C3 CD46 C8A	2.43e-04	96	45	4	M39581
Pathway	BIOCARTA_ALTERNATIVE_PATHWAY	C3 C8A	3.54e-04	9	45	2	M22072
Pubmed	Expression, purification and characterization of human vacuolar-type H(+)-ATPase subunit d1 and d2 in Escherichia coli.	ATP6V0D1 ATP6V0D2	2.83e-06	2	59	2	24631925
Pubmed	The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome.	C3 CD46	2.83e-06	2	59	2	25879158
Pubmed	Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome.	C3 CD46	2.83e-06	2	59	2	18796626
Pubmed	The paramyxoviruses simian virus 5 and mumps virus recruit host cell CD46 to evade complement-mediated neutralization.	C3 CD46	2.83e-06	2	59	2	19457998
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	IGSF10 IGF1R MLEC PGAP1 LAMC1 ALG11 LAMC3 ERP29 CD46 EXT2 SELENOI	4.87e-06	1201	59	11	35696571
Pubmed	Contribution of the repeating domains of membrane cofactor protein (CD46) of the complement system to ligand binding and cofactor activity.	C3 CD46	8.48e-06	3	59	2	1717583
Pubmed	Association analysis of SNPs in GRHL3, FAF1, and KCNJ2 with NSCPO sub-phenotypes in Han Chinese.	KCNJ2 GRHL3	8.48e-06	3	59	2	34255421
Pubmed	uPAR enhances malignant potential of triple-negative breast cancer by directly interacting with uPA and IGF1R.	IGF1R PLAU	8.48e-06	3	59	2	27502396
Pubmed	Laminin isoforms containing the gamma3 chain are unable to bind to integrins due to the absence of the glutamic acid residue conserved in the C-terminal regions of the gamma1 and gamma2 chains.	LAMC1 LAMC3	8.48e-06	3	59	2	18697739
Pubmed	The d subunit plays a central role in human vacuolar H(+)-ATPases.	ATP6V0D1 ATP6V0D2	1.69e-05	4	59	2	18752060
Pubmed	Binding of netrin-4 to laminin short arms regulates basement membrane assembly.	LAMC1 LAMC3	1.69e-05	4	59	2	17588941
Pubmed	New functional and structural insights from updated mutational databases for complement factor H, Factor I, membrane cofactor protein and C3.	C3 CD46	1.69e-05	4	59	2	25188723
Pubmed	Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy.	C3 PLAU	1.69e-05	4	59	2	30300579
Pubmed	Host resistance to intracellular infection: mutation of natural resistance-associated macrophage protein 1 (Nramp1) impairs phagosomal acidification.	ATP6V0D1 ATP6V0D2	1.69e-05	4	59	2	9670047
Pubmed	The Complement Regulatory Protein CD46 Deficient Mouse Spontaneously Develops Dry-Type Age-Related Macular Degeneration-Like Phenotype.	C3 CD46	1.69e-05	4	59	2	27295359
Pubmed	Elimination by necrosis, not apoptosis, of embryonic extraocular muscles in the muscular dysgenesis mutant of the mouse.	CACNA1S LAMC1	2.82e-05	5	59	2	14618389
Pubmed	Expression and function of the mouse V-ATPase d subunit isoforms.	ATP6V0D1 ATP6V0D2	4.23e-05	6	59	2	12963731
Pubmed	The CD46-Jagged1 interaction is critical for human TH1 immunity.	C3 CD46	4.23e-05	6	59	2	23086448
Pubmed	Atypical postinfectious glomerulonephritis is associated with abnormalities in the alternative pathway of complement.	C3 CD46	4.23e-05	6	59	2	23235567
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	GPD2 NAMPT ATP6V0D1 ACADSB EXOC3 COPS6 DHX8	4.47e-05	560	59	7	35241646
Pubmed	A new nomenclature for the laminins.	LAMC1 LAMC3	5.91e-05	7	59	2	7921537
Pubmed	Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome.	C3 CD46	5.91e-05	7	59	2	20513133
Pubmed	Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome.	C3 CD46	5.91e-05	7	59	2	19861685
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	NAMPT ATP6V0D1 GPX3 CPNE3 LAMC1 C3 PLAU C8A PZP	7.54e-05	1070	59	9	23533145
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	LAMC1 C3 C8A PZP F5	7.66e-05	257	59	5	16335952
Pubmed	Insulin-like growth factor II receptor, transforming growth factor-beta, and Cdk4 expression and the developmental epigenetics of mouse palate morphogenesis and dysmorphogenesis.	IGF1R PLAU	7.87e-05	8	59	2	9438420
Pubmed	Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway.	C3 CD46	7.87e-05	8	59	2	14670299
Pubmed	C3 Glomerulopathy	C3 CD46	7.87e-05	8	59	2	20301598
Pubmed	Molecular organization and function of the complement system.	C3 C8A	7.87e-05	8	59	2	3052276
Pubmed	Protein profile of exosomes from trabecular meshwork cells.	LAMC1 C3 PZP	8.08e-05	49	59	3	21362503
Pubmed	Altered expression of inflammation-associated genes in oviductal cells following follicular fluid exposure: implications for ovarian carcinogenesis.	NAMPT GPX3	1.01e-04	9	59	2	24186266
Pubmed	Intersubspecific subcongenic mouse strain analysis reveals closely linked QTLs with opposite effects on body weight.	GPD2 SCN7A	1.26e-04	10	59	2	21451961
Pubmed	Trophoblast-specific expression and function of the integrin alpha 7 subunit in the peri-implantation mouse embryo.	LAMC1 LAMC3	1.26e-04	10	59	2	11784026
Pubmed	Basement membrane deposition of nidogen 1 but not nidogen 2 requires the nidogen binding module of the laminin gamma1 chain.	LAMC1 LAMC3	1.54e-04	11	59	2	21084308
Pubmed	Diversity of mouse proton-translocating ATPase: presence of multiple isoforms of the C, d and G subunits.	ATP6V0D1 ATP6V0D2	1.54e-04	11	59	2	12527205
Pubmed	Genetic Atypical Hemolytic-Uremic Syndrome	C3 CD46	1.54e-04	11	59	2	20301541
Pubmed	Regional differences in the expression of laminin isoforms during mouse neural tube development.	LAMC1 LAMC3	1.54e-04	11	59	2	21524702
Pubmed	Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.	LAMC1 LAMC3	1.54e-04	11	59	2	23472759
Pubmed	Hereditary Spastic Paraplegia Overview	PGAP1 DDHD2 ATL1	1.71e-04	63	59	3	20301682
Pubmed	The γ3 chain of laminin is widely but differentially expressed in murine basement membranes: expression and functional studies.	LAMC1 LAMC3	2.18e-04	13	59	2	22222602
Pubmed	Basement membrane composition in the early mouse embryo day 7.	LAMC1 LAMC3	2.93e-04	15	59	2	15895400
Pubmed	ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest.	RPS5 C3 CHM PZP	3.04e-04	189	59	4	29449217
Pubmed	Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.	LAMC1 LAMC3	3.34e-04	16	59	2	17601529
Pubmed	Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.	LAMC1 LAMC3	4.25e-04	18	59	2	11311202
Pubmed	Risk of meningioma and common variation in genes related to innate immunity.	C3 CD46 C8A F5	4.29e-04	207	59	4	20406964
Pubmed	Common variation in genes related to innate immunity and risk of adult glioma.	C3 CD46 C8A F5	4.37e-04	208	59	4	19423540
Pubmed	New genetic associations detected in a host response study to hepatitis B vaccine.	NAMPT C3 CASR LAMC3 CARD11 CD46 C8A	4.78e-04	824	59	7	20237496
Pubmed	Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts.	ATP6V0D1 ATP6V0D2	5.27e-04	20	59	2	22982048
Pubmed	Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.	LAMC1 LAMC3	5.27e-04	20	59	2	22911573
Pubmed	Schwann cell myelination requires integration of laminin activities.	LAMC1 LAMC3	5.82e-04	21	59	2	22767514
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	GPD2 REXO4 NAMPT ATP6V0D1 MLEC RPS5 LAMC3 ERP29 DHX8	6.28e-04	1425	59	9	30948266
Pubmed	Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.	IGF1R LAMC1 C3	6.29e-04	98	59	3	19834535
Pubmed	The vacuolar (H+)-ATPases--nature's most versatile proton pumps.	ATP6V0D1 ATP6V0D2	6.39e-04	22	59	2	11836511
Pubmed	WNT4 and RSPO1 together are required for cell proliferation in the early mouse gonad.	IGF1R FOXL2	6.39e-04	22	59	2	23095882
Pubmed	Proton translocation driven by ATP hydrolysis in V-ATPases.	ATP6V0D1 ATP6V0D2	6.39e-04	22	59	2	12788495
Pubmed	Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes.	ATP6V0D1 ATP6V0D2	6.39e-04	22	59	2	14580332
Pubmed	Neurotransmitter release: the dark side of the vacuolar-H+ATPase.	ATP6V0D1 ATP6V0D2	6.39e-04	22	59	2	14597263
Pubmed	Kir2.1 Interaction with Stk38 Promotes Invasion and Metastasis of Human Gastric Cancer by Enhancing MEKK2-MEK1/2-ERK1/2 Signaling.	KCNJ2 C3	6.39e-04	22	59	2	29549164
Pubmed	Coupling of rotation and catalysis in F(1)-ATPase revealed by single-molecule imaging and manipulation.	ATP6V0D1 ATP6V0D2	6.39e-04	22	59	2	17662945
Pubmed	Renal collecting system growth and function depend upon embryonic γ1 laminin expression.	LAMC1 LAMC3	7.00e-04	23	59	2	21903675
Pubmed	Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).	ATP6V0D1 GPX3 CPNE3 LAMC1 EXT2	7.12e-04	417	59	5	19199708
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	MLEC ACADSB LAMC1 ALG11 MORC4 CDH17	7.35e-04	638	59	6	31182584
Pubmed	Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor.	ATP6V0D1 ATP6V0D2	8.28e-04	25	59	2	2874839
Pubmed	Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.	LAMC1 LAMC3	8.96e-04	26	59	2	24742657
Pubmed	Integrating genetic and network analysis to characterize genes related to mouse weight.	GPD2 SCN7A	1.12e-03	29	59	2	16934000
Pubmed	Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.	C3 CD46	1.27e-03	31	59	2	19344414
Pubmed	Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network.	GPD2 MLEC ERP29 EXT2	1.36e-03	282	59	4	35007762
Pubmed	Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.	CD46 C8A	1.36e-03	32	59	2	18842294
Pubmed	Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway.	ATP6V0D1 LAMC1	1.44e-03	33	59	2	29149599
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	ATP6V0D1 MLEC RPS5 LAMC1 C3 LAMC3 ERP29 EXT2	1.50e-03	1297	59	8	33545068
Pubmed	Early embryonic expression of murine coagulation system components.	PLAU F5	1.53e-03	34	59	2	11154109
Pubmed	Regulation of prefrontal patterning and connectivity by retinoic acid.	PLXNC1 EPHA8	1.53e-03	34	59	2	34599305
Pubmed	Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma.	ATP6V0D1 C8A	1.53e-03	34	59	2	34050187
Pubmed	Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice.	IGF1R FOXL2	1.53e-03	34	59	2	23300479
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	GPD2 RPS5 CPNE3 EXOC3 LAMC1 F5 DHX8	1.69e-03	1024	59	7	24711643
Cytoband	19p13.2	ZNF625 ZNF700 ZNF564 ZNF433	2.21e-04	229	59	4	19p13.2
Cytoband	1q32	CACNA1S CD46	1.84e-03	49	59	2	1q32
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	C3 ZNF625 ZNF700 ZNF564 ZNF433	3.60e-03	797	59	5	chr19p13
GeneFamily	Complement system\|Sushi domain containing	C3 CD46 C8A	1.04e-04	36	46	3	492
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C3 PZP	2.25e-04	9	46	2	1234
GeneFamily	Laminin subunits	LAMC1 LAMC3	4.11e-04	12	46	2	626
GeneFamily	V-type ATPases	ATP6V0D1 ATP6V0D2	1.55e-03	23	46	2	415
GeneFamily	Selenoproteins	GPX3 SELENOI	1.83e-03	25	46	2	890
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF347 ZNF625 ZNF700 ZNF564 ZNF529 ZNF433	9.30e-03	718	46	6	28
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PGAP1 SCN7A GPX3 LAMC1 C3 ATL1	1.90e-07	189	59	6	f7d57723b8fb0f1e1485f51e3eff93ec0f39761e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KATNAL2 IGF1R CASR PLAU AK3	4.66e-06	185	59	5	03f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 LAMC1 C3 PLAU	5.44e-06	191	59	5	7d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 SCN7A GPX3 C3 PLAU	5.58e-06	192	59	5	11088878043a6ff95ba1970361256a82e434b80a
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGSF10 NAMPT GPX3 C3 PLAU	5.58e-06	192	59	5	d7faa993f68e530ad55185505384ae155d36c222
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 SCN7A GPX3 LAMC1 C3	5.72e-06	193	59	5	f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	PGAP1 SCN7A GPX3 LAMC1 C3	5.72e-06	193	59	5	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 SCN7A GPX3 LAMC1 C3	5.72e-06	193	59	5	85faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCell	facs-MAT-Fat-3m-Mesenchymal\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 SCN7A GPX3 LAMC1 C3	5.72e-06	193	59	5	110a7d2ba7d066c2be38be98b643b76c520dd980
ToppCell	facs-SCAT-Fat-3m-Mesenchymal\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 SCN7A GPX3 LAMC1 C3	5.87e-06	194	59	5	14b614f039bc866a1348a2728a68b7d254c7748c
ToppCell	facs-SCAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 SCN7A GPX3 LAMC1 C3	5.87e-06	194	59	5	68c7bfead1158641928cc276f599b4a79e06c73c
ToppCell	facs-SCAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 SCN7A GPX3 LAMC1 C3	5.87e-06	194	59	5	f6aeae6a1e4017e341323fd4784c9e3bae00552b
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NAMPT GPX3 LAMC1 C3 PLAU	6.01e-06	195	59	5	fc43cd295f2cc3f6e9442232e028944f011c82cc
ToppCell	5'-Adult-Appendix\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NAMPT GPX3 LAMC1 C3 PLAU	6.17e-06	196	59	5	a579211ef14f348d0c5a290553150222dfbf1515
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NAMPT GPX3 LAMC1 C3 PLAU	6.32e-06	197	59	5	ab5d3ebc73bd7cfc64381d14b92878b370205186
ToppCell	5'-Adult-Appendix-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NAMPT GPX3 LAMC1 C3 PLAU	6.32e-06	197	59	5	b11a5d909942a4299cbc0b27332b1a3f66f3bccd
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGSF10 SCN7A GPX3 LAMC1 C3	6.64e-06	199	59	5	0019cfaa586a450c2e4952d1184a540561c8d0ba
ToppCell	droplet-Liver-Hepatocytes-18m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX3 ATP6V0D2 DDHD2 ITGA9	8.79e-06	98	59	4	95162072f3afc95e46f29db3d79ebd930bc09726
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sema3c-Inhibitory_Gad1Gad2_Htr3a.Sema3c_(Interneuron,__(candidate_CGE-derived_12))\|Hippocampus / BrainAtlas - Mouse McCarroll V32	RTL1 C3 C8A	5.07e-05	54	59	3	a582a89185bd4c3508a3349e68fca070743e6e75
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sema3c-Inhibitory_Gad1Gad2_Htr3a.Sema3c_(Interneuron,__(candidate_CGE-derived_12))-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	RTL1 C3 C8A	5.07e-05	54	59	3	c593dd57c79c770c7939d641dcfaf6c9c0ff5710
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sema3c\|Hippocampus / BrainAtlas - Mouse McCarroll V32	RTL1 C3 C8A	5.07e-05	54	59	3	b1adbf4632694746511e3051d4306a42223cbb92
ToppCell	368C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PLXNC1 PGAP1 GPX3 ATL1	5.46e-05	156	59	4	4877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCell	368C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PLXNC1 PGAP1 GPX3 ATL1	5.46e-05	156	59	4	1d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NAMPT PLXNC1 ITGA9 CDH17	5.88e-05	159	59	4	6c0ef40f64d2e35eaae3d0002e3c1f22d1239736
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NAMPT PLXNC1 ITGA9 CDH17	5.88e-05	159	59	4	745a59c33b04620c5329bdd50e74a8e611f2dc55
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	RPS5 SCN7A GPX3 C3	7.44e-05	169	59	4	84b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCell	CTRL-Myeloid-Neutrophil\|Myeloid / Disease state, Lineage and Cell class	NAMPT IGF1R PLXNC1 KCNJ2	7.61e-05	170	59	4	151dabe1d240dde414c881bf4fa816c69fa1c32d
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGF1R PLXNC1 CPNE3 C3	7.97e-05	172	59	4	d354424c1f861b6607dfd63b9724f4c237b30275
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NAMPT FOXL2 PLXNC1 PZP	8.15e-05	173	59	4	9eaec30f9a3655b53ece1b66848201a7f85bbdf5
ToppCell	severe_influenza-Neutrophil\|World / disease group, cell group and cell class (v2)	NAMPT PLXNC1 KCNJ2 F5	8.33e-05	174	59	4	f9f07436b7d3f190800cd85d229f007032f391e1
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KATNAL2 RPS5 GPX3 C3	8.33e-05	174	59	4	68a6ed81e7e1f95b61f7ee20403980fa3a8db4d0
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GARIN4 CD46 CEBPZOS ATL1	8.52e-05	175	59	4	aa168aeb9ad71aa6c0c28a0657c9eb92a0b28183
ToppCell	CF-Myeloid-Neutrophil\|Myeloid / Disease state, Lineage and Cell class	NAMPT IGF1R PLXNC1 PLAU	8.52e-05	175	59	4	8020c3a34f77e68e8149f87481fb1dddd2ac675e
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-9\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GARIN4 ZNF347 LAMC1 ZNF564	8.90e-05	177	59	4	ae55773c531099a9e94f44f01ba48b5e71dddc53
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CARD11 C8A FYB2 CDH17	8.90e-05	177	59	4	43dce527392f3b8364bb6a55268ce9d6518d3a29
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NAMPT PLXNC1 ITGA9 PZP	9.10e-05	178	59	4	af9bcee71fb44a6342d4b92bba5b8ddfeeaa24b2
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NAMPT PLXNC1 PLAU CDH17	9.10e-05	178	59	4	94a86f5232fffa6a92a30ea21fb44eec33b4d6c8
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KATNAL2 ACADSB CASR PLAU	9.50e-05	180	59	4	0b653b1b653b40f3b8711d1312029a4a8a4961db
ToppCell	facs-Lung-EPCAM-18m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ2 ATP6V0D2 GRHL3 MORC4	9.91e-05	182	59	4	6685a0abd9c3a79d03b6a578e5d7fa86a9d74117
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 LAMC1 C3	9.91e-05	182	59	4	f4b74c2756989812abe4e7055ec8918f69d56025
ToppCell	facs-Lung-EPCAM-18m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ2 ATP6V0D2 GRHL3 MORC4	9.91e-05	182	59	4	f8eb35eb7f2b8ad47d527ae9ff8a9ddbcd2eedce
ToppCell	severe-Myeloid-Neutrophils_1\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	NAMPT PLXNC1 KCNJ2 CD46	1.01e-04	183	59	4	60a6112aa4fc4f5debda4c7e81b37539ba2e4e6e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KATNAL2 SCN7A CASR AK3	1.03e-04	184	59	4	e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPX3 LAMC1 C3 PLAU	1.06e-04	185	59	4	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNJ2 FYB2 CDH17 EPHA8	1.06e-04	185	59	4	c3d1a312569f3d619f7295812741cbf068ec6c1f
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 LAMC1 C3	1.08e-04	186	59	4	35c88cc4eb388811fcac4323b549e5897fa8dc27
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACADSB PGAP1 CASR PLAU	1.08e-04	186	59	4	8eafd4bea692f7ef33de27dd53f9d1fe67deaad8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KATNAL2 CASR PLAU AK3	1.08e-04	186	59	4	1850583d23903d08226aeb0edb3e07b0994330e4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KATNAL2 CASR PLAU AK3	1.08e-04	186	59	4	4dafc215c42e7949f932a3627359c107943b5d6b
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 LAMC1 C3	1.08e-04	186	59	4	d998c5b00083cf2a7cd5341a98b7374b4de73c63
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCN7A GPX3 LAMC1 C3	1.08e-04	186	59	4	7582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCell	CF\|World / Disease state, Lineage and Cell class	NAMPT IGF1R PLXNC1 PLAU	1.10e-04	187	59	4	eec4d4e4a658e3a61c05745167a1a5e3d39bb43e
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	PGAP1 SCN7A LAMC1 C3	1.10e-04	187	59	4	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	facs-Heart-LA-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 LAMC1 C3	1.10e-04	187	59	4	f3ef3f5a761f8306edc39bf16e76e44aae6fa7f6
ToppCell	facs-Heart-LA-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 LAMC1 C3	1.10e-04	187	59	4	1669df899b1759c338ffce196fe009840123cfcd
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SCN7A CASR PLAU AK3	1.10e-04	187	59	4	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	RA-14._Fibroblast_III\|RA / Chamber and Cluster_Paper	NAMPT PGAP1 C3 PLAU	1.15e-04	189	59	4	46e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCell	facs-BAT-Fat-18m-Mesenchymal\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX3 LAMC1 LAMC3 PLAU	1.15e-04	189	59	4	bba28f57a0708515fdd5acd9592dbbe4a4f57116
ToppCell	facs-BAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX3 LAMC1 LAMC3 PLAU	1.15e-04	189	59	4	cf293b23a4c0e8a0c9f09115b1d53d9b11de72e2
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 C3 PLAU	1.15e-04	189	59	4	6e52cac679e0541ca5f2be316bdabdbc34da6e18
ToppCell	facs-BAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX3 LAMC1 LAMC3 PLAU	1.15e-04	189	59	4	87323e86a5b5d159920a07e6bd7ef5e3438cd085
ToppCell	LV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	SCN7A GPX3 LAMC1 C3	1.17e-04	190	59	4	12992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCell	3'_v3-Lung-Myeloid_Dendritic-DC2\|Lung / Manually curated celltypes from each tissue	PLXNC1 C3 PLAU CDH17	1.17e-04	190	59	4	468525c05e38158a3b8a445882b2d63dfb1d2c63
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 C3 PLAU	1.17e-04	190	59	4	ad0f5605db6b694445ec9bd5dc8d2d834358c0f9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KATNAL2 CASR PLAU AK3	1.17e-04	190	59	4	3dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAMPT SCN7A C3 PLAU	1.19e-04	191	59	4	f5ce33af56178333730be308253943c54a0724cf
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCN7A GPX3 LAMC1 C3	1.19e-04	191	59	4	44a9a6768084dafc641ad455b65862bfd4cc0cb9
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 LAMC1 C3	1.19e-04	191	59	4	6cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCell	droplet-Fat-Gat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 LAMC1 C3	1.19e-04	191	59	4	850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 C3 PLAU	1.19e-04	191	59	4	83d1915835df6f2eb23f87986d695e71398edb9d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KATNAL2 SCN7A CASR AK3	1.19e-04	191	59	4	963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 LAMC1 C3	1.19e-04	191	59	4	8b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCell	ASK440-Mesenchymal\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	IGSF10 PGAP1 SCN7A GPX3	1.19e-04	191	59	4	f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 LAMC1 C3	1.19e-04	191	59	4	1efb47743b6834b64cb0f61721ddbe875b1a66ca
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPX3 LAMC1 C3 PLAU	1.19e-04	191	59	4	4e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCell	ASK440-Mesenchymal-Fibroblast\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	IGSF10 PGAP1 SCN7A GPX3	1.19e-04	191	59	4	387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCell	5'-Adult-LymphNode-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGSF10 GPX3 C3 PLAU	1.19e-04	191	59	4	054e9a79bd1486fd812bc7418fb091664fe3a646
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IGSF10 GPX3 LAMC1 C3	1.19e-04	191	59	4	997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGSF10 GPX3 C3 PLAU	1.22e-04	192	59	4	9479e9859140ba98abfe88414de0b28fc2bf43b7
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 SCN7A GPX3 LAMC1	1.22e-04	192	59	4	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 LAMC1 C3	1.22e-04	192	59	4	5e6f8206ee0b10cdba79a7c4a05452cb025a5512
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGSF10 GPX3 LAMC1 C3	1.22e-04	192	59	4	29bee88b45e23f16543ffc7cc361bc5da5d16a2b
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	SCN7A GPX3 LAMC1 C3	1.22e-04	192	59	4	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 SCN7A LAMC1 C3	1.22e-04	192	59	4	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	NS-critical-d_0-4-Myeloid-Neutrophil\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NAMPT PLXNC1 KCNJ2 PLAU	1.22e-04	192	59	4	3db74359c30172a51177e00eac1f48f483e15578
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGSF10 GPX3 LAMC1 C3	1.22e-04	192	59	4	cdc652dbfabe41b324fd85c1ed933d29fb73a49f
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 SCN7A GPX3 LAMC1	1.22e-04	192	59	4	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGSF10 SCN7A GPX3 C3	1.22e-04	192	59	4	c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 LAMC1 C3	1.22e-04	192	59	4	2d9e2262f1342fe17735f21f733c029d1275e955
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 LAMC1 C3	1.22e-04	192	59	4	136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCell	droplet-Fat-Mat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 SCN7A LAMC1 C3	1.24e-04	193	59	4	ebd090d7801480b3cee45caac3d30cc991836769
ToppCell	PND28-Mesenchymal-Mesenchymal_structural\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGSF10 GPX3 LAMC1 C3	1.24e-04	193	59	4	ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 LAMC1 C3	1.24e-04	193	59	4	0a665531d581d4e3941e29d3f95569da8f166447
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 LAMC1 C3	1.24e-04	193	59	4	49600db68ed65cafc67bd45a285b364e4f5f88af
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGSF10 GPX3 LAMC1 C3	1.24e-04	193	59	4	7c0d84b92470bfda2db1e5007feee7c1235a0a78
ToppCell	severe-Myeloid-Neutrophils_3\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	NAMPT PLXNC1 CD46 F5	1.24e-04	193	59	4	f4d43dfbf4115dd0f843ea5cf08049220342a047
ToppCell	LA-14._Fibroblast_III\|LA / Chamber and Cluster_Paper	NAMPT PGAP1 C3 PLAU	1.24e-04	193	59	4	7426c291bac59e539c427bcaae18abc7d397d44e
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SCN7A GPX3 LAMC1 C3	1.24e-04	193	59	4	261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN7A GPX3 LAMC1 C3	1.24e-04	193	59	4	24ce1f37cca655415410d2403a52d1ebb3332280
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGSF10 GPX3 LAMC1 C3	1.24e-04	193	59	4	30481fb01c7acf85beae10213f038da86bed6777
Disease	Vasculitis, Hemorrhagic	C3 PLAU	3.54e-06	2	56	2	C0042386
Disease	Henoch-Schoenlein Purpura	C3 PLAU	3.54e-06	2	56	2	C0034152
Disease	Purpura, Nonthrombocytopenic	C3 PLAU	3.54e-06	2	56	2	C0242461
Disease	Purpura Hemorrhagica	C3 PLAU	3.54e-06	2	56	2	C0376362
Disease	Rheumatoid Purpura	C3 PLAU	3.54e-06	2	56	2	C0086922
Disease	Septic Phlebitis, Sagittal Sinus	PLAU F5	1.06e-05	3	56	2	C0751823
Disease	Sagittal Sinus Thrombophlebitis	PLAU F5	1.06e-05	3	56	2	C0751824
Disease	Sagittal Sinus Thrombosis	PLAU F5	1.06e-05	3	56	2	C0338575
Disease	myocardial infarction (biomarker_via_orthology)	IGF1R C3 CASR PLAU C8A	1.35e-05	160	56	5	DOID:5844 (biomarker_via_orthology)
Disease	Complement deficiency disease	C3 CD46 C8A	3.39e-05	33	56	3	C0272242
Disease	atypical hemolytic-uremic syndrome (is_implicated_in)	C3 CD46	9.83e-05	8	56	2	DOID:0080301 (is_implicated_in)
Disease	Hemolytic-uremic syndrome	C3 CD46	1.26e-04	9	56	2	cv:C0019061
Disease	C3 glomerulopathy	C3 CD46	1.26e-04	9	56	2	C4087273
Disease	Atypical hemolytic-uremic syndrome	C3 CD46	1.26e-04	9	56	2	cv:C2931788
Disease	Atypical Hemolytic Uremic Syndrome	C3 CD46	1.58e-04	10	56	2	C2931788
Disease	WNT1-inducible-signaling pathway protein 1 measurement	C8A FYB2	1.58e-04	10	56	2	EFO_0008321
Disease	Hemolytic-Uremic Syndrome	C3 CD46	1.92e-04	11	56	2	C0019061
Disease	Posterior Choroidal Artery Infarction	PLAU F5	1.92e-04	11	56	2	C0887799
Disease	Cerebral Infarction, Left Hemisphere	PLAU F5	1.92e-04	11	56	2	C0751010
Disease	Anterior Choroidal Artery Infarction	PLAU F5	1.92e-04	11	56	2	C0751012
Disease	Cerebral Infarction, Right Hemisphere	PLAU F5	1.92e-04	11	56	2	C0751011
Disease	Subcortical Infarction	PLAU F5	1.92e-04	11	56	2	C0751014
Disease	Cerebral Infarction	PLAU F5	1.92e-04	11	56	2	C0007785
Disease	Thromboembolism	PLAU F5	2.31e-04	12	56	2	C0040038
Disease	Respiratory Depression	CACNA1S IGF1R	2.72e-04	13	56	2	C0235063
Disease	Respiratory Insufficiency	CACNA1S IGF1R	2.72e-04	13	56	2	C0035229
Disease	amyotrophic lateral sclerosis (biomarker_via_orthology)	IGF1R C3	2.72e-04	13	56	2	DOID:332 (biomarker_via_orthology)
Disease	Respiratory Failure	CACNA1S IGF1R	2.72e-04	13	56	2	C1145670
Disease	MAJOR AFFECTIVE DISORDER 2	ITGA9 CDH17	4.72e-04	17	56	2	C1839839
Disease	Antibody Deficiency Syndrome	C3 C8A	4.72e-04	17	56	2	C0003257
Disease	colorectal adenoma (is_marker_for)	GPX3 F5	6.58e-04	20	56	2	DOID:0050860 (is_marker_for)
Disease	Deep Vein Thrombosis	PLAU F5	7.26e-04	21	56	2	C0149871
Disease	Venous Thrombosis	PLAU F5	7.26e-04	21	56	2	C0042487
Disease	Immunologic Deficiency Syndromes	C3 C8A	8.72e-04	23	56	2	C0021051
Disease	pre-eclampsia (is_implicated_in)	CD46 F5	1.03e-03	25	56	2	DOID:10591 (is_implicated_in)
Disease	Agouti-related protein measurement	ATP6V0D1 CDH17	1.20e-03	27	56	2	EFO_0008016
Disease	tooth eruption	CACNA1S KCNJ2	1.30e-03	28	56	2	GO_0044691
Disease	cerebral infarction (is_implicated_in)	ITGA9 F5	1.39e-03	29	56	2	DOID:3526 (is_implicated_in)
Disease	RS-warfarin measurement	PLAU C8A FYB2	1.87e-03	128	56	3	EFO_0803325

Protein segments in the cluster

Peptide	Gene	Start	Entry
KKYPEAVYVVYTGDV	ALG11	91	Q2TAA5
KKYPFILEVYYKSTE	CEBPZOS	46	A8MTT3
DKEYYYTKEEQFKQV	COPS6	101	Q7L5N1
DDEKYFRKPYNFLKY	C8A	201	P07357
KEVGYYNVYAKKGER	CASR	506	P41180
EKYKLDKESYPVFYL	ERP29	106	P30040
EEYIPFKQYAGKYVL	GPX3	51	P22352
VEPTEKFYYIYNEKG	C3	236	P01024
DYYFEVVQKLKFGVY	CPNE3	66	O75131
GVGYTKDYPVEKYFR	ACADSB	391	P45954
EKYPDEYKGYEEITF	CHM	306	P24386
GDLKPAIVKVYDYYE	PZP	1446	P20742
YEPVLFEEKHYYKVD	KCNJ2	326	P63252
PYIEAEVKYGIKEYA	GPD2	531	P43304
IYDGKKYYIYGEPRK	MAGEB5	161	Q9BZ81
KPYYEIGERVDYKCK	CD46	51	P15529
LYIEFVKGYYDNPKV	MLEC	191	Q14165
QLYKGEYDIFKYAPI	GARIN4	31	Q8IYT1
YEDQTKPVLEYYQKK	AK3	176	Q9UIJ7
YYKEAPFKNVTEYDG	IGF1R	526	P08069
YAKDIPTYKEEVKSY	PLXNC1	1471	O60486
ESYYFVKFQKYPKIV	KATNAL2	76	Q8IYT4
YQYIIAKFPFYEKNK	FOXL2	81	P58012
FYKGDKDNKYVPYSE	DDHD2	116	O94830
LIPCYEEYKKKYGEE	ITGA9	176	Q13797
YYKYKQVAPKPEDIF	IGSF10	401	Q6WRI0
EKYGFPEENIYKVYK	GRHL3	546	Q8TE85
VEYFKAYIKIYQGEE	ATL1	326	Q8WXF7
EEYYGYRPKKDIVQI	CACNA1S	1541	Q13698
PNGIILEYEIKYYEK	EPHA8	466	P29322
YVSPEQLAGFDKYKY	SELENOI	6	Q9C0D9
VEPRLKGKVYDYYVE	KLHDC7A	281	Q5VTJ3
DEVFNDPKVLKSYYY	LAMC1	261	P11047
VEDYFNDFAKIKKPY	EXOC3	576	O60645
YVFYAVAKDEYGKPL	CDH17	306	Q12864
VAYKYNVDYKPDIED	PIWIL3	141	Q7Z3Z3
EFYYPELYKLVTGKE	CARD11	96	Q9BXL7
IYYVVDPGFVKQKVY	DHX8	851	Q14562
YGKCVYDKYVKPTEP	REXO4	271	Q9GZR2
KFAQEHYVELYEKPY	RTL1	441	A6NKG5
QDYIAVKEKYAKYLP	RPS5	36	P46782
FIDYPKKEDYIVYLG	PLAU	226	P00749
KAKYGELEPYVYFNK	SFXN2	306	Q96NB2
FKKIVYREYEPYFKK	F5	61	P12259
YREYEPYFKKEKPQS	F5	66	P12259
YEDVYKTKNNYPKID	FYB2	521	Q5VWT5
KPAYNKQDFEYTKEY	MORC4	371	Q8TE76
KVKYEETVFYGLQYI	NAMPT	51	P43490
YMFEYPEYQKIELPK	PGAP1	41	Q75T13
YDYQEYGEKPYKCKQ	ZNF564	131	Q8TBZ8
HKAYEYQEYGPKPYK	ZNF700	151	Q9H0M5
VYIYALKKYVDDFGV	EXT2	106	Q93063
GEKPYKYNEYGKAFS	ZNF347	621	Q96SE7
LEDVDPYYYKKKNTF	SCN7A	66	Q01118
HKPYEYQEYGQKPYK	ZNF625	56	Q96I27
DSEKPYEYKEYEKVF	ZNF529	166	Q6P280
AYEYQEYGQKPYKCK	ZNF433	131	Q8N7K0
YGVFYAYVKLKEQEI	ATP6V0D2	311	Q8N8Y2
YEQVKNVADYYPEYK	ATP6V0D1	261	P61421
DDIFKDPKVLQSYYY	LAMC3	246	Q9Y6N6