Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

1.47e-052772GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

1.47e-052772GO:0044017
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

4.39e-053772GO:0043993
GeneOntologyMolecularFunctionSMAD binding

GATA4 CREBBP EP300 SMAD1

3.42e-0486774GO:0046332
GeneOntologyCellularComponentchromatin

HOXA13 NR2C1 KLF12 NSMF STAG1 INCENP CECR2 MORF4L1 GATA4 POU3F4 PRKDC FOXN3 ONECUT1 CREBBP EP300 SMAD1 DNMT1

2.15e-0514807717GO:0000785
HumanPhenoAbnormal hallux phalanx morphology

HOXA13 GATA4 ABCC9 CREBBP EP300

4.04e-0646285HP:0010057
HumanPhenoDeep plantar creases

ABCC9 FBXO11 CREBBP EP300

4.10e-0621284HP:0001869
HumanPhenoBroad hallux phalanx

GATA4 ABCC9 CREBBP EP300

7.20e-0624284HP:0010059
HumanPhenoMinor feet anomalies

ABCC9 FBXO11 CREBBP EP300

1.01e-0526284HP:0010613
HumanPhenoAbnormal feet morphology

ABCC9 FBXO11 CREBBP EP300

1.01e-0526284HP:0010611
HumanPhenoBroad distal phalanx of finger

FBXO11 GNAS CREBBP EP300

1.18e-0527284HP:0009836
HumanPhenoFull cheeks

FAT4 GATA4 FBXO11 GNAS CREBBP EP300 MAPK8IP3

1.23e-05151287HP:0000293
HumanPhenoBenign neoplasm of the central nervous system

FAT4 CCBE1 GNAS MN1 CREBBP EP300

1.73e-05105286HP:0100835
HumanPhenoAbnormal nasal bridge morphology

GHR SETD2 FAT4 NSMF STAG1 CCBE1 NUP88 GATA4 ABCC9 FBXO11 PRKDC GNAS MN1 CREBBP EP300 MAPK8IP3

1.77e-0510292816HP:0000422
HumanPhenoAplasia/Hypoplasia involving bones of the feet

GHR HOXA13 FAT4 CCBE1 ABCC9 FBXO11 GNAS EP300 MAPK8IP3

1.83e-05298289HP:0006494
HumanPhenoFlat face

FAT4 CCBE1 ABCC9 MN1 CREBBP EP300

1.83e-05106286HP:0012368
HumanPhenoSyringomyelia

SETD2 FBXO11 CREBBP EP300

2.68e-0533284HP:0003396
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

2.91e-052282HP:0008107
HumanPhenoPericardial lymphangiectasia

FAT4 CCBE1

2.91e-052282HP:0005183
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

2.91e-052282HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

2.91e-052282HP:0001042
HumanPhenoAbnormality of skeletal maturation

GHR NSMF CCBE1 GATA4 ABCC9 FBXO11 POU3F4 GNAS CREBBP EP300

3.21e-054052810HP:0000927
HumanPhenoAbnormality of the first metatarsal bone

HOXA13 ABCC9 EP300

4.10e-0513283HP:0010054
HumanPhenoAbnormality of toe proximal phalanx

HOXA13 ABCC9 EP300

5.20e-0514283HP:0010184
HumanPhenoDelayed skeletal maturation

GHR NSMF CCBE1 GATA4 ABCC9 FBXO11 POU3F4 CREBBP EP300

6.90e-05352289HP:0002750
HumanPhenoLow-set ears

FAT4 STAG1 CCBE1 NUP88 GATA4 ANO1 FBXO11 PRKDC POMK MN1 CREBBP EP300 MAPK8IP3

7.06e-057612813HP:0000369
HumanPhenoMeningioma

GNAS MN1 CREBBP EP300

8.53e-0544284HP:0002858
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

8.71e-053282HP:0008752
HumanPhenoPhobia

CREBBP EP300

8.71e-053282HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

8.71e-053282HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

8.71e-053282HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

8.71e-053282HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

8.71e-053282HP:0005895
HumanPhenoSpinal cord lesion

SETD2 FBXO11 CREBBP EP300

1.02e-0446284HP:0100561
HumanPhenoBroad phalanx of the toes

GATA4 ABCC9 CREBBP EP300

1.11e-0447284HP:0010174
HumanPhenoChiari type I malformation

SETD2 STAG1 CREBBP EP300

1.20e-0448284HP:0007099
HumanPhenoBroad phalanx

GATA4 ABCC9 FBXO11 GNAS CREBBP EP300

1.21e-04148286HP:0006009
HumanPhenoBroad phalanges of the hand

GATA4 ABCC9 FBXO11 GNAS CREBBP EP300

1.21e-04148286HP:0009768
HumanPhenoHirsutism

SETD2 CCBE1 ABCC9 FBXO11 GNAS CREBBP EP300

1.24e-04216287HP:0001007
HumanPhenoBroad finger

GATA4 ABCC9 FBXO11 GNAS CREBBP EP300

1.50e-04154286HP:0001500
HumanPhenoAbnormal midface morphology

GHR AMPD2 SETD2 FAT4 CCBE1 GATA4 FBXO11 GNAS MN1 CREBBP EP300 MAPK8IP3

1.61e-047042812HP:0000309
HumanPhenoAbnormal proximal phalanx morphology of the hand

HOXA13 GNAS CREBBP EP300

1.65e-0452284HP:0009834
HumanPhenoIncreased body weight

GHR SETD2 GATA4 ABCC9 FBXO11 POU3F4 GNAS CREBBP EP300 MAPK8IP3

1.67e-044912810HP:0004324
HumanPhenoBroad long bones

GATA4 ABCC9 FBXO11 GNAS CREBBP EP300

1.67e-04157286HP:0005622
HumanPhenoTrichiasis

CREBBP EP300

1.74e-044282HP:0001128
HumanPhenoVisceral hemangioma

CREBBP EP300

1.74e-044282HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

1.74e-044282HP:0011087
HumanPhenoWidened distal phalanges

CREBBP EP300

1.74e-044282HP:0006200
HumanPhenoVascular ring

CREBBP EP300

1.74e-044282HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

1.74e-044282HP:0031207
HumanPhenoAbnormal metatarsal morphology

HOXA13 FAT4 ABCC9 GNAS POMK EP300

1.79e-04159286HP:0001832
HumanPhenoWide nasal bridge

SETD2 FAT4 CCBE1 NUP88 GATA4 ABCC9 FBXO11 PRKDC CREBBP EP300

2.22e-045082810HP:0000431
HumanPhenoAbnormality of the incisor

STAG1 CCBE1 ABCC9 CREBBP EP300

2.60e-04108285HP:0000676
HumanPhenoAbnormal lower limb bone morphology

GHR HOXA13 FAT4 CCBE1 NUP88 GATA4 ABCC9 FBXO11 GNAS POMK CREBBP EP300 MAPK8IP3

2.75e-048662813HP:0040069
HumanPhenoPulmonary lymphangiectasia

FAT4 CCBE1

2.88e-045282HP:0006521
HumanPhenoIntestinal lymphangiectasia

FAT4 CCBE1

2.88e-045282HP:0002593
HumanPhenoAbnormal pulmonary lymphatics

FAT4 CCBE1

2.88e-045282HP:0006529
HumanPhenoShort first metatarsal

HOXA13 EP300

2.88e-045282HP:0010105
HumanPhenoPapillary cystadenoma of the epididymis

CREBBP EP300

2.88e-045282HP:0009715
HumanPhenoSupernumerary cusp

CREBBP EP300

2.88e-045282HP:0033777
HumanPhenoEpididymal neoplasm

CREBBP EP300

2.88e-045282HP:0030421
HumanPhenoAbnormal distal phalanx morphology of finger

HOXA13 ABCC9 FBXO11 GNAS CREBBP EP300

2.93e-04174286HP:0009832
HumanPhenoObesity

GHR SETD2 GATA4 FBXO11 POU3F4 GNAS CREBBP EP300 MAPK8IP3

2.95e-04425289HP:0001513
HumanPhenoHypertrichosis

SETD2 STAG1 CCBE1 ABCC9 FBXO11 GNAS CREBBP EP300 MAPK8IP3

2.95e-04425289HP:0000998
HumanPhenoDuane anomaly

NSMF FBXO11 MN1

3.16e-0425283HP:0009921
HumanPhenoIncomitant strabismus

NSMF FBXO11 MN1

3.16e-0425283HP:0025068
HumanPhenoAbnormal incisor morphology

CCBE1 ABCC9 CREBBP EP300

3.27e-0462284HP:0011063
HumanPhenoShort metatarsal

HOXA13 FAT4 GNAS EP300

3.27e-0462284HP:0010743
HumanPhenoNeoplasm of the central nervous system

FAT4 CCBE1 GNAS MN1 CREBBP EP300

3.32e-04178286HP:0100006
HumanPhenoShort toe

GHR HOXA13 ABCC9 GNAS EP300

3.63e-04116285HP:0001831
HumanPhenoProminent forehead

SETD2 FAT4 ABCC9 PRKDC MN1 CREBBP EP300

4.00e-04261287HP:0011220
HumanPhenoAplasia/Hypoplasia of metatarsal bones

HOXA13 FAT4 GNAS EP300

4.17e-0466284HP:0001964
HumanPhenoLarge foramen magnum

CREBBP EP300

4.31e-046282HP:0002700
HumanPhenoDeeply set eye

STAG1 GATA4 FBXO11 PRKDC CREBBP EP300 MAPK8IP3

4.49e-04266287HP:0000490
HumanPhenoFlared metaphysis

GATA4 ABCC9 FBXO11 GNAS CREBBP EP300

4.85e-04191286HP:0003015
HumanPhenoBroad eyebrow

FBXO11 CREBBP EP300

4.94e-0429283HP:0011229
HumanPhenoAbnormality of the outer ear

HOXA13 AMPD2 FAT4 STAG1 CCBE1 NUP88 GATA4 ANO1 FBXO11 POU3F4 PRKDC POMK MN1 CREBBP EP300 MAPK8IP3

5.08e-0413372816HP:0000356
HumanPhenoNeoplasm of the nervous system

FAT4 CCBE1 GNAS MN1 CREBBP EP300

5.42e-04195286HP:0004375
HumanPhenoLong eyelashes

STAG1 ABCC9 FBXO11 CREBBP EP300

5.93e-04129285HP:0000527
HumanPhenoDeviated nasal septum

CREBBP EP300

6.02e-047282HP:0004411
HumanPhenoHypoplastic iliac wing

CCBE1 CREBBP EP300

6.03e-0431283HP:0002866
HumanPhenoAbnormal toe phalanx morphology

HOXA13 GATA4 ABCC9 CREBBP EP300

6.14e-04130285HP:0010161
HumanPhenoAbnormal cheek morphology

FAT4 GATA4 FBXO11 GNAS CREBBP EP300 MAPK8IP3

6.40e-04282287HP:0004426
HumanPhenoFunctional abnormality of the inner ear

SETD2 FAT4 NSMF CCBE1 GATA4 ABCC9 POU3F4 PRKDC GNAS POMK CREBBP EP300 VCL DNMT1

6.53e-0410772814HP:0011389
HumanPhenoAplasia/hypoplasia involving bones of the lower limbs

GHR HOXA13 FAT4 CCBE1 ABCC9 FBXO11 GNAS EP300 MAPK8IP3

6.67e-04474289HP:0006493
HumanPhenoAbnormal location of ears

FAT4 STAG1 CCBE1 NUP88 GATA4 ANO1 FBXO11 PRKDC POMK MN1 CREBBP EP300 MAPK8IP3

6.70e-049452813HP:0000357
HumanPhenoLymphedema

FAT4 CCBE1 ABCC9 DNMT1

7.14e-0476284HP:0001004
HumanPhenoFrontal upsweep of hair

FBXO11 CREBBP EP300

7.27e-0433283HP:0002236
HumanPhenoAbnormality of upper limb joint

GHR HOXA13 SETD2 FAT4 STAG1 CCBE1 NUP88 ABCC9 FBXO11 CREBBP EP300

7.51e-047052811HP:0009810
HumanPhenoSensorineural hearing impairment

SETD2 FAT4 NSMF CCBE1 ABCC9 POU3F4 PRKDC GNAS POMK CREBBP EP300 VCL DNMT1

7.67e-049582813HP:0000407
HumanPhenoAplasia/hypoplasia of the 1st metatarsal

HOXA13 EP300

7.99e-048282HP:0010067
HumanPhenoShort phalanx of hallux

HOXA13 EP300

7.99e-048282HP:0010111
HumanPhenoAplasia/hypoplasia of proximal toe phalanx

HOXA13 EP300

7.99e-048282HP:0010203
HumanPhenoAbnormality of the inner ear

SETD2 FAT4 NSMF CCBE1 GATA4 ABCC9 POU3F4 PRKDC GNAS POMK CREBBP EP300 VCL DNMT1

8.34e-0411022814HP:0000359
HumanPhenoAbnormality of globe location or size

SETD2 FAT4 NSMF STAG1 CCBE1 NUP88 GATA4 ABCC9 FBXO11 PRKDC POMK MN1 CREBBP EP300 MAPK8IP3

8.48e-0412462815HP:0000489
HumanPhenoAplasia/Hypoplasia of toe

GHR HOXA13 ABCC9 GNAS EP300

8.62e-04140285HP:0001991
HumanPhenoAbnormal dental morphology

GHR FAT4 CCBE1 ABCC9 CREBBP EP300 MAPK8IP3

9.08e-04299287HP:0006482
HumanPhenoAbnormality of the distal phalanx of the thumb

GNAS CREBBP EP300

9.41e-0436283HP:0009617
HumanPhenoAbnormal scrotum morphology

HOXA13 FAT4 GATA4 CREBBP EP300

9.48e-04143285HP:0000045
HumanPhenoTruncal obesity

GHR GNAS CREBBP EP300

9.52e-0482284HP:0001956
HumanPhenoAbnormality of globe location

SETD2 FAT4 NSMF STAG1 CCBE1 NUP88 GATA4 ABCC9 FBXO11 PRKDC MN1 CREBBP EP300 MAPK8IP3

1.01e-0311222814HP:0100886
HumanPhenoPilomatrixoma

CREBBP EP300

1.02e-039282HP:0030434
HumanPhenoCervical cord compression

CREBBP EP300

1.02e-039282HP:0002341
HumanPhenoShort phalanx of finger

HOXA13 GATA4 ABCC9 FBXO11 GNAS CREBBP EP300

1.04e-03306287HP:0009803
HumanPhenoSupernumerary tooth

FAT4 CCBE1 CREBBP EP300

1.09e-0385284HP:0011069
MousePhenodecreased circulating glucagon level

GHR GNAS ONECUT1 CREBBP

2.07e-0620664MP:0002696
MousePhenoperinatal lethality

GHR CYP1A2 ARHGAP5 CACNB1 FAT4 CELSR3 CECR2 MORF4L1 GATA4 FBXO11 GNAS MN1 CREBBP EP300 RUFY3 MAPK8IP3 BAHCC1 MGRN1

3.09e-0611306618MP:0002081
MousePhenoabnormal circulating glucagon level

GHR GNAS ONECUT1 CREBBP

3.64e-0540664MP:0002695
MousePhenothin myocardium

GATA4 BCAR1 EP300 VCL MGRN1

4.93e-0585665MP:0002652
MousePhenocyanosis

CYP1A2 CELSR3 ANO1 MN1 EP300 RUFY3 MAPK8IP3

9.11e-05226667MP:0001575
MousePhenothin ventricle myocardium compact layer

GATA4 CREBBP EP300

1.08e-0420663MP:0010556
MousePhenoperinatal lethality, incomplete penetrance

GHR CYP1A2 CECR2 GATA4 FBXO11 GNAS MN1 CREBBP BAHCC1 MGRN1

1.15e-045036610MP:0011090
MousePhenoabnormal interatrial septum morphology

FAT4 GATA4 CREBBP EP300 MGRN1

1.48e-04107665MP:0000282
MousePhenolethality during fetal growth through weaning, incomplete penetrance

GHR CYP1A2 HOXA13 CECR2 GATA4 FBXO11 PRKDC FOXN3 GNAS ONECUT1 MN1 CREBBP EP300 BAHCC1 MGRN1

1.86e-0411246615MP:0011112
MousePhenoabnormal oxygen level

CYP1A2 CELSR3 ANO1 MN1 EP300 RUFY3 MAPK8IP3

1.97e-04256667MP:0001574
MousePhenolethality during fetal growth through weaning, complete penetrance

HOXA13 ARHGAP5 CACNB1 FAT4 CELSR3 STAG1 MORF4L1 GATA4 ANO1 FBXO11 GNAS MN1 CREBBP EP300 RUFY3 MAPK8IP3

2.10e-0412696616MP:0011111
MousePhenoabnormal extraembryonic tissue morphology

GHR HOXA13 BCL9L SETD2 STAG1 INCENP CCBE1 GATA4 GAB3 CREBBP EP300 SMAD1 DNMT1

2.75e-049086613MP:0002086
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

1.59e-052752IPR014744
DomainHAT_KAT11

CREBBP EP300

1.59e-052752PF08214
DomainKIX

CREBBP EP300

1.59e-052752PS50952
DomainZnF_TAZ

CREBBP EP300

1.59e-052752SM00551
DomainCBP_P300_HAT

CREBBP EP300

1.59e-052752IPR031162
DomainDUF902

CREBBP EP300

1.59e-052752PF06001
Domain-

CREBBP EP300

1.59e-0527521.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

1.59e-052752IPR010303
Domain-

CREBBP EP300

1.59e-0527521.10.1630.10
DomainCreb_binding

CREBBP EP300

1.59e-052752PF09030
Domain-

CREBBP EP300

1.59e-0527521.10.246.20
Domainzf-TAZ

CREBBP EP300

1.59e-052752PF02135
DomainZF_TAZ

CREBBP EP300

1.59e-052752PS50134
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

1.59e-052752IPR013178
DomainKAT11

CREBBP EP300

1.59e-052752SM01250
DomainZnf_TAZ

CREBBP EP300

1.59e-052752IPR000197
DomainKIX_dom

CREBBP EP300

1.59e-052752IPR003101
DomainKIX

CREBBP EP300

1.59e-052752PF02172
DomainCBP_P300_HAT

CREBBP EP300

1.59e-052752PS51727
DomainBromodomain_CS

CECR2 CREBBP EP300

1.51e-0426753IPR018359
DomainNuc_rcpt_coact

CREBBP EP300

2.36e-046752IPR009110
DomainBROMODOMAIN_1

CECR2 CREBBP EP300

4.38e-0437753PS00633
DomainBromodomain

CECR2 CREBBP EP300

4.74e-0438753PF00439
DomainBROMODOMAIN_2

CECR2 CREBBP EP300

5.94e-0441753PS50014
DomainBROMO

CECR2 CREBBP EP300

6.38e-0442753SM00297
DomainBromodomain

CECR2 CREBBP EP300

6.38e-0442753IPR001487
Domain-

CECR2 CREBBP EP300

6.38e-04427531.20.920.10
DomainBAH

DNMT1 BAHCC1

8.55e-0411752SM00439
DomainBAH

DNMT1 BAHCC1

8.55e-0411752PF01426
DomainBAH

DNMT1 BAHCC1

8.55e-0411752PS51038
DomainBAH_dom

DNMT1 BAHCC1

8.55e-0411752IPR001025
DomainCS

NUDCD1 CYB5R4

1.40e-0314752PF04969
DomainCS_dom

NUDCD1 CYB5R4

1.84e-0316752IPR007052
DomainCS

NUDCD1 CYB5R4

1.84e-0316752PS51203
DomainZZ

CREBBP EP300

2.34e-0318752PF00569
DomainZF_ZZ_2

CREBBP EP300

2.34e-0318752PS50135
DomainZF_ZZ_1

CREBBP EP300

2.34e-0318752PS01357
DomainZnf_ZZ

CREBBP EP300

2.60e-0319752IPR000433
DomainZnF_ZZ

CREBBP EP300

2.60e-0319752SM00291
DomainPentatricopeptide_repeat

PRKDC GNAS

3.81e-0323752IPR002885
Domain-

NUDCD1 CYB5R4

3.81e-03237522.60.40.790
DomainUBQ-conjugating_AS

UBE2G2 UBE2H

4.50e-0325752IPR023313
DomainHSP20-like_chaperone

NUDCD1 CYB5R4

4.86e-0326752IPR008978
Domain-

POU3F4 ONECUT1

5.23e-03277521.10.260.40
DomainLambda_DNA-bd_dom

POU3F4 ONECUT1

6.02e-0329752IPR010982
DomainASX_HYDROXYL

FAT4 CELSR3 CCBE1

7.61e-03100753PS00010
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

SETD2 MORF4L1 PRKDC CREBBP EP300

5.68e-0665565M39682
PathwayREACTOME_SUMOYLATION

NR2C1 STAG1 INCENP NUP88 CREBBP EP300 DNMT1

9.28e-06189567M27214
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

ONECUT1 CREBBP EP300

3.21e-0516563M27121
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

NR2C1 UBE2G2 UBE2H STAG1 INCENP RBBP5 SHISA5 NICN1 NUP88 PSMC6 FBXO11 PRKDC POMK CREBBP EP300 SMAD1 DNMT1

3.61e-0514755617M19806
PathwayPID_HES_HEY_PATHWAY

GHR GATA4 CREBBP EP300

3.82e-0548564M288
PathwayWP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX

CREBBP EP300 DNMT1

7.51e-0521563M39593
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

BCL9L RBBP5 EP300

1.45e-0426563MM14793
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

1.54e-045562MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

1.54e-045562M48020
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

1.54e-045562M48023
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

1.54e-045562M27228
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

2.30e-046562M22062
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

3.21e-047562MM1573
PathwayWP_TYPE_2_PAPILLARY_RENAL_CELL_CARCINOMA

SETD2 CREBBP EP300

3.26e-0434563M39771
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

4.27e-048562M22058
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

4.27e-048562M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

4.27e-048562M48024
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

4.27e-048562M46443
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

BCL9L RBBP5 CREBBP EP300

4.62e-0491564M27101
PathwayPID_FOXM1_PATHWAY

ONECUT1 CREBBP EP300

5.29e-0440563M176
PathwayREACTOME_SUMOYLATION

STAG1 INCENP NUP88 EP300 DNMT1

5.44e-04169565MM14919
PathwayBIOCARTA_CELL2CELL_PATHWAY

BCAR1 VCL

5.48e-049562MM1366
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

5.48e-049562M47451
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

ONECUT1 CREBBP EP300

6.11e-0442563M17541
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

CREBBP EP300

6.83e-0410562M27945
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

8.33e-0411562MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

8.33e-0411562M48021
PathwayREACTOME_STAT3_NUCLEAR_EVENTS_DOWNSTREAM_OF_ALK_SIGNALING

EP300 DNMT1

8.33e-0411562M42523
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

CREBBP EP300

8.33e-0411562M26924
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

UBE2G2 UBE2H STAG1 INCENP RBBP5 SHISA5 NUP88 PSMC6 FBXO11 PRKDC POMK EP300 SMAD1 DNMT1

8.36e-0413895614MM15307
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

9.97e-0412562M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

9.97e-0412562M27765
PathwayBIOCARTA_CELL2CELL_PATHWAY

BCAR1 VCL

9.97e-0412562M12851
PathwayPID_AR_TF_PATHWAY

NR2C1 CREBBP EP300

1.21e-0353563M151
PathwayWP_TGFBETA_SIGNALING_PATHWAY

CREBBP EP300 SMAD1

1.21e-0353563MM15880
PathwayWP_TGFBETA_RECEPTOR_SIGNALING

CREBBP EP300 SMAD1

1.35e-0355563M39351
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

CREBBP EP300

1.37e-0314562M27808
PathwayKEGG_CELL_CYCLE

STAG1 PRKDC CREBBP EP300

1.52e-03125564M7963
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

1.57e-0315562MM1339
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

1.57e-0315562M10183
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

1.57e-0315562MM1439
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

CREBBP EP300

1.57e-0315562M953
PathwayPID_P53_REGULATION_PATHWAY

FBXO11 CREBBP EP300

1.65e-0359563M261
PathwayPID_FAK_PATHWAY

BCAR1 VCL MAPK8IP3

1.65e-0359563M281
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

CREBBP EP300 SMAD1

1.65e-0359563M39886
PathwayREACTOME_GASTRULATION

GATA4 PSMC6 CREBBP EP300

1.70e-03129564M46433
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

1.79e-0316562M1296
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

1.79e-0316562MM1420
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

1.79e-0316562M8516
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES

CREBBP EP300

1.79e-0316562M27940
PathwayREACTOME_SARS_COV_1_TARGETS_HOST_INTRACELLULAR_SIGNALLING_AND_REGULATORY_PATHWAYS

PSMC6 EP300

1.79e-0316562M46428
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

2.03e-0317562MM1509
PathwayREACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA

CREBBP EP300

2.03e-0317562M48025
PathwayREACTOME_CYTOSOLIC_SENSORS_OF_PATHOGEN_ASSOCIATED_DNA

PRKDC CREBBP EP300

2.08e-0364563M27046
PathwayREACTOME_PROTEIN_UBIQUITINATION

UBE2G2 UBE2H PRKDC

2.18e-0365563MM15490
PathwayPID_RB_1PATHWAY

CREBBP EP300 DNMT1

2.18e-0365563M279
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

BCL9L RBBP5 PSMC6 CREBBP EP300

2.27e-03233565M27099
PathwayPID_HDAC_CLASSI_PATHWAY

NR2C1 CREBBP EP300

2.28e-0366563M101
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

CREBBP EP300

2.28e-0318562M26942
Pubmed

Activation of Smad1-mediated transcription by p300/CBP.

CREBBP EP300 SMAD1

1.09e-08378310673036
Pubmed

Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules.

STAG1 ONECUT1 CREBBP EP300

4.17e-081678422780989
Pubmed

E1A inhibits transforming growth factor-beta signaling through binding to Smad proteins.

CREBBP EP300 SMAD1

1.08e-07578310497242
Pubmed

Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms.

CREBBP EP300 SMAD1

1.08e-07578311239394
Pubmed

A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction.

CREBBP EP300 SMAD1

2.16e-07678310887155
Pubmed

A unique SUMO-2-interacting motif within LANA is essential for KSHV latency.

PRKDC CREBBP EP300

3.77e-07778324278015
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

BCL9L DENND2A INCENP CECR2 ANO1 PSMC6 CREBBP EP300 VCL

4.84e-0742578924999758
Pubmed

Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells.

CREBBP EP300 SMAD1

9.03e-07978316801560
Pubmed

The effects of trichostatin A on mRNA expression of chromatin structure-, DNA methylation-, and development-related genes in cloned mouse blastocysts.

CREBBP EP300 DNMT1

9.03e-07978318241125
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

METAP1 ARHGAP5 NR2C1 NSMF CELSR3 STAG1 MORF4L1 FBXO11 PRKDC CREBBP EP300 RUFY3 MAPK8IP3 DNMT1

9.25e-071285781435914814
Pubmed

Interaction network of human early embryonic transcription factors.

BCL9L NR2C1 RBBP5 NUP88 GATA4 CREBBP EP300 BAHCC1

1.26e-0635178838297188
Pubmed

Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma.

FAT4 FBXO11 CREBBP

1.77e-061178324349473
Pubmed

Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator.

ABCC9 CREBBP EP300

2.35e-061278312189208
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

4.97e-06278227881875
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

4.97e-06278234845315
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

4.97e-06278219729597
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

4.97e-06278239287984
Pubmed

The mouse mutation severe combined immune deficiency (scid) is on chromosome 16.

PRKDC MGRN1

4.97e-0627822908877
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

4.97e-06278220717166
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

4.97e-06278225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

4.97e-06278211559821
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

4.97e-06278232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

4.97e-06278219822209
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

4.97e-06278224522976
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

4.97e-06278221847097
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

4.97e-06278234813504
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

4.97e-06278220301699
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

4.97e-06278224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

4.97e-06278237816914
Pubmed

CAS directly interacts with vinculin to control mechanosensing and focal adhesion dynamics.

BCAR1 VCL

4.97e-06278223974298
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

4.97e-06278211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

4.97e-06278210918613
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

4.97e-06278235502657
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

4.97e-06278231898871
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

4.97e-06278230888860
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

4.97e-06278227881443
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

4.97e-06278219272189
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

4.97e-06278232690000
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

4.97e-06278230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

4.97e-06278221803292
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

4.97e-0627829811832
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

4.97e-06278224089570
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

4.97e-06278215706485
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

4.97e-06278239266679
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

4.97e-06278222303793
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

4.97e-06278234732714
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

4.97e-06278234019788
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

4.97e-06278215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

4.97e-06278229460469
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

4.97e-06278224551300
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

4.97e-06278233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

4.97e-0627829018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

4.97e-06278224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

4.97e-06278230135524
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

4.97e-06278216596650
Pubmed

Granulation pattern, but not GSP or GHR mutation, is associated with clinical characteristics in somatostatin-naive patients with somatotroph adenomas.

GHR GNAS

4.97e-06278223288882
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

4.97e-06278229217654
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

4.97e-06278210049825
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

4.97e-06278227380996
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

4.97e-06278229170789
Pubmed

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

CREBBP EP300

4.97e-06278221555743
Pubmed

CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.

CREBBP EP300

4.97e-06278212646247
Pubmed

Stability of the hepatocyte nuclear factor 6 transcription factor requires acetylation by the CREB-binding protein coactivator.

ONECUT1 CREBBP

4.97e-06278215304484
Pubmed

Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.

CREBBP EP300

4.97e-06278211867645
Pubmed

The scid mouse mutant.

PRKDC MGRN1

4.97e-0627823416632
Pubmed

Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.

CREBBP EP300

4.97e-06278211963968
Pubmed

Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.

CREBBP EP300

4.97e-0627829528808
Pubmed

Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.

CREBBP EP300

4.97e-06278212696060
Pubmed

CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.

CREBBP EP300

4.97e-06278236109165
Pubmed

Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.

CREBBP EP300

4.97e-06278212242694
Pubmed

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.

CREBBP EP300

4.97e-06278231182547
Pubmed

Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.

CREBBP EP300

4.97e-06278230635043
Pubmed

p300 Functions as a coactivator of transcription factor GATA-4.

GATA4 EP300

4.97e-06278211481322
Pubmed

Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.

CREBBP EP300

4.97e-06278227648933
Pubmed

Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.

CREBBP EP300

4.97e-06278210610021
Pubmed

Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.

CREBBP EP300

4.97e-06278237314181
Pubmed

Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.

CREBBP EP300

4.97e-06278212397173
Pubmed

CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.

CREBBP EP300

4.97e-06278215641773
Pubmed

Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein.

CREBBP EP300

4.97e-0627829733868
Pubmed

Rubinstein-Taybi syndrome in Chinese population with four novel mutations.

CREBBP EP300

4.97e-06278233063428
Pubmed

EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.

CREBBP EP300

4.97e-06278234506759
Pubmed

Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms.

CREBBP EP300

4.97e-06278222177454
Pubmed

NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain.

CREBBP EP300 VCL

7.21e-061778334637754
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

BCL9L RBBP5 PRKDC BCAR1 CREBBP EP300 DNMT1

1.00e-0533278737433992
Pubmed

A multiprotein complex necessary for both transcription and DNA replication at the β-globin locus.

MORF4L1 PRKDC EP300

1.40e-052178320808282
Pubmed

The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB.

CREBBP EP300

1.49e-05378218070920
Pubmed

The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism.

GATA4 EP300

1.49e-05378211994297
Pubmed

BMP2-activated Erk/MAP kinase stabilizes Runx2 by increasing p300 levels and histone acetyltransferase activity.

EP300 SMAD1

1.49e-05378220851880
Pubmed

Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP.

CREBBP EP300

1.49e-05378227903646
Pubmed

Inhibition of p300/CBP by early B-cell factor.

CREBBP EP300

1.49e-05378212748286
Pubmed

Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.

CREBBP EP300

1.49e-05378224340053
Pubmed

Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response.

CREBBP EP300

1.49e-05378219273602
Pubmed

Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation.

CREBBP EP300

1.49e-05378215649887
Pubmed

DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes.

CREBBP EP300

1.49e-05378226951377
Pubmed

Global loss of imprinting leads to widespread tumorigenesis in adult mice.

PRKDC DNMT1

1.49e-05378216226703
Pubmed

CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes.

CREBBP EP300

1.49e-05378221789216
Pubmed

Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex.

CREBBP EP300

1.49e-05378212050117
Pubmed

Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.

CREBBP EP300

1.49e-05378216237459
Pubmed

The IFNgamma-induced STAT1-CBP/P300 association, required for a normal response to the cytokine, is disrupted in Brucella-infected macrophages.

CREBBP EP300

1.49e-05378219041714
Pubmed

MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress.

SETD2 MORF4L1

1.49e-05378228673974
InteractionCTBP1 interactions

KLF12 AMPD2 UBE2H RBBP5 NTAQ1 RTN4 FBXO11 CREBBP EP300 DNMT1

3.25e-064067710int:CTBP1
InteractionEGR2 interactions

BCL9L NR2C1 UBE2H RBBP5 CREBBP EP300 BAHCC1

4.09e-06171777int:EGR2
InteractionPSG8 interactions

FAT4 CELSR3 MANEAL MGRN1

1.79e-0541774int:PSG8
InteractionNCOA6 interactions

GHR RBBP5 PRKDC CREBBP EP300 SMAD1

1.95e-05145776int:NCOA6
InteractionGSC interactions

BCL9L CREBBP EP300 SMAD1 BAHCC1

2.07e-0587775int:GSC
InteractionRBBP7 interactions

NR2C1 UBE2H STAG1 RBBP5 MORF4L1 GATA4 CREBBP EP300 DNMT1 BAHCC1

2.25e-055077710int:RBBP7
InteractionEWSR1 interactions

BCL9L DENND2A UBE2H INCENP CECR2 GATA4 ANO1 PSMC6 ZSWIM4 CREBBP EP300 VCL SMAD1

3.58e-059067713int:EWSR1
InteractionNEUROG1 interactions

CREBBP EP300 SMAD1

4.97e-0519773int:NEUROG1
InteractionCRX interactions

BCL9L NR2C1 RBBP5 GATA4 CREBBP EP300 BAHCC1

5.28e-05254777int:CRX
InteractionKAT2A interactions

KLF12 PRKDC CREBBP EP300 SMAD1 MAPK8IP3

6.55e-05180776int:KAT2A
InteractionHDAC1 interactions

NR2C1 STAG1 RBBP5 MORF4L1 NUP88 GATA4 PSMC6 NUDCD1 POMK CREBBP EP300 SMAD1 DNMT1 BAHCC1

6.92e-0511087714int:HDAC1
InteractionMSH6 interactions

UBE2H MORF4L1 GATA4 PRKDC CREBBP EP300 DNMT1

7.93e-05271777int:MSH6
InteractionMTA1 interactions

NR2C1 UBE2H STAG1 GATA4 BCAR1 EP300 DNMT1

1.04e-04283777int:MTA1
InteractionHBP1 interactions

UBE2H INCENP CREBBP EP300 SMAD1

1.09e-04123775int:HBP1
InteractionSMAD2 interactions

HOXA13 STAG1 RBBP5 GATA4 PRKDC CREBBP EP300 SMAD1

1.10e-04385778int:SMAD2
InteractionH3-3A interactions

NR2C1 UBE2H STAG1 INCENP RBBP5 MORF4L1 GATA4 PRKDC CREBBP EP300 DNMT1

1.24e-047497711int:H3-3A
InteractionCSNK2B interactions

AMPD2 SETD2 UBE2H RBBP5 NTAQ1 U2SURP GATA4 CREBBP EP300 DNMT1

1.29e-046257710int:CSNK2B
InteractionHOXB7 interactions

PRKDC CREBBP EP300

1.31e-0426773int:HOXB7
InteractionSPATA32 interactions

NTAQ1 BCAR1

1.43e-045772int:SPATA32
Cytoband3p21.31

SETD2 CELSR3 SHISA5 NICN1

2.67e-051007843p21.31
Cytoband2p16.3

RTN4 FBXO11

6.44e-04227822p16.3
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.24e-0317562486
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.40e-031856291
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5

SHD KLF12 CACNB1 RSPH3 NSMF UBE2H MANEAL ANO1 POU3F4 FOXN3 MAPKBP1 MAPK8IP3

1.41e-057437712Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#3

SHD KLF12 CACNB1 NSMF ANO1 POU3F4 FOXN3 MAPKBP1 RUFY3

3.40e-05447779Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#5

SHD KLF12 CACNB1 RSPH3 NSMF UBE2H CECR2 MANEAL ANO1 FOXN3 MAPKBP1

3.65e-056887711Facebase_RNAseq_e10.5_Mandibular Arch_2500_K5
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#3_top-relative-expression-ranked_500

GHR KLF12 FAT4 RTN4 MAPKBP1 MN1

6.26e-05188776gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500_k3
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#2

SHD KLF12 CACNB1 RSPH3 NSMF UBE2H MANEAL ANO1 FOXN3 MAPKBP1 POMK

7.65e-057477711Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K2
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCBE1 PCSK7 POU3F4 SLITRK3 VCL

1.66e-05181785beb2771820956be8b190c0088ae3c4efdb53c897
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A ANKRD34B UBE2H MAPKBP1 VCL

2.04e-051897858c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A ANKRD34B UBE2H MAPKBP1 VCL

2.04e-051897855d902a4660a27548764bf04c6de152b565da835c
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GHR DENND2A KLF12 ANO1 ABCC9

2.04e-051897857ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GHR DENND2A FAT4 CCBE1 ANO1

2.15e-051917856688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A KLF12 CCBE1 ANO1 ABCC9

2.20e-051927854022f208eb5db760abd0aac782a25e8ab63efc64
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GHR DENND2A KLF12 ANO1 ABCC9

2.20e-05192785992d08092edbc68c47b945deb8708379738c239a
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

GHR DENND2A FAT4 COLGALT2 MN1

2.20e-05192785a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

GHR DENND2A FAT4 COLGALT2 MN1

2.26e-051937859ab47b360bee1d4f1092c2269e58acebe9584021
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GHR FAT4 CCBE1 ANO1 ABCC9

2.43e-05196785a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GHR FAT4 CCBE1 ANO1 ABCC9

2.43e-051967853e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DENND2A ANO1 ABCC9 MMP17 VCL

2.68e-05200785786f1ae53e60b5ffbf4bfd393d10b802478148b3
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

GHR DENND2A ANO1 ABCC9 VCL

2.68e-0520078567dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DENND2A ANO1 ABCC9 MMP17 VCL

2.68e-05200785b5b5a32925f225610fe25a021a742d6397162863
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DENND2A ANO1 ABCC9 MMP17 VCL

2.68e-05200785d2fcd3bd7c3223875f027eeb48ff621192a5f242
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DENND2A ANO1 ABCC9 MMP17 VCL

2.68e-052007854e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCellControl_saline-Mesenchymal_myocytic|Control_saline / Treatment groups by lineage, cell group, cell type

GHR DENND2A ANO1 ABCC9 VCL

2.68e-052007855ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

DENND2A ANO1 ABCC9 MMP17 VCL

2.68e-05200785bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellnormal_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs|Myeloid_cells / Location, Cell class and cell subclass

MANEAL COLGALT2 ZCCHC2 MMP17

1.36e-04149784a34d095b8e0fe59d69d84e4fd2fe4ccb82f92e4f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND2A ANO1 ABCC9 MMP17

1.62e-041567846365b69ede98bc866e996bc52736b00401aacf6f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND2A ANO1 ABCC9 MMP17

1.67e-04157784bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCelldroplet-Fat-Bat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR3 TSPOAP1 RBBP5 AK8

2.16e-041687846fddc957a0503455d8c165862b5eb8e5fdb8a510
ToppCelldroplet-Fat-Bat-18m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR3 TSPOAP1 RBBP5 AK8

2.16e-04168784794035cb63353a7d02fd9939deb5b4d075c9d95a
ToppCelldroplet-Fat-Bat-18m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR3 TSPOAP1 RBBP5 AK8

2.16e-041687841e23b634f96e88b976a523ca1f3fc08f6fe9b239
ToppCellIonocyte-iono-1|World / Class top

KLF12 UBE2H PLCL2 GNAS

2.21e-041697844b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

AMPD2 RSPH3 PLCL2 MMP17

2.26e-0417078409bcbc7eb3b1d35cf03f01ce2f2fe37373382dd4
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB1 INCENP DNAH10 POU3F4

2.41e-04173784506efcaa5afd6ed5e565c4c4def6a4505fea97c5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCBE1 PLCL2 FOXN3 MINDY1

2.69e-0417878451d2188406f04329311b2efd1108fc36617a860e
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA13 CCBE1 POU3F4 VCL

2.75e-04179784e860dca9b28ac5af61804bfd729cd39257cdb352
ToppCellfacs-Skin-Anagen-3m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GHR CEACAM19 ANO1 PAK6

2.75e-041797844a072526c3a524a7aed99bdb32a07a1ce1f48972
ToppCell10x5'-bone_marrow-Lymphocytic_B-Pre-B|bone_marrow / Manually curated celltypes from each tissue

DENND2A CECR2 SMAD1 BAHCC1

2.93e-04182784a5fd392178c2f533e265d2e3ce63b90c2553e4c1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GHR CCBE1 ABCC9 VCL

2.93e-0418278444764676ed3f51ba171ce63f669390392fa50a43
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GHR CCBE1 ABCC9 VCL

2.93e-04182784d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND2A ANO1 ABCC9 MMP17

2.99e-041837848a799807fbf24456a9811e0c64068187940a2f71
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SHD CELSR3 MANEAL MMP17

2.99e-041837849dfb398b9995d562864fe688861a831ada0814cd
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAT4 CECR2 FMR1NB MN1

2.99e-04183784351d575339038bd4a66f408da518c567444208e8
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

DNAH10 TSPOAP1 GAB3 VCL

3.05e-04184784791f1bcb954aadc63d4117c400537d036f68734d
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D122|Adult / Lineage, Cell type, age group and donor

GHR DENND2A COLGALT2 MN1

3.05e-041847842b7e6f91e11c228f0521e099886867d9e998e78d
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PRODH2 KLF12 GATA4 FOXN3

3.11e-041857841d874608aa2062024323512f68889219471b2f00
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SHD CELSR3 MANEAL MMP17

3.11e-04185784512f489daeb3b72d4578dc6f4d0ebb5f38d5bbab
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SHD DENND2A PRKDC GNAS

3.18e-0418678410565fce7e1b4ec88bc8e1ed6410a83800be5014
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NSMF UBE2G2 UBE2H MAPKBP1

3.18e-0418678477bebf576eb9b96ecb4fefb8a82a31aaaa917fc0
ToppCellRV-07._Pericyte|RV / Chamber and Cluster_Paper

DENND2A ANO1 ABCC9 COLGALT2

3.18e-04186784c533b264fbe12bc35467486fc7fbde24ba968fe1
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NSMF UBE2G2 UBE2H MAPKBP1

3.18e-0418678413bc41c60fd628af31899a5e8b480e06cc4781be
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP5 MORF4L1 FOXN3 CREBBP

3.24e-04187784663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A UBE2H CECR2 VCL

3.24e-0418778477886f99c229610abd28c4c370d2c7d1536c9782
ToppCellILEUM-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PCSK7 FBXO11 GNAS MAPKBP1

3.24e-041877840099def970fbc828756fbf853eca2ce77b8cd342
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DENND2A ANO1 ABCC9 BCAR1

3.24e-04187784a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

GHR DENND2A CCBE1 ANO1

3.24e-0418778492d468dde81125d51daf7abd4703741abe1ab91c
ToppCellwk_08-11-Epithelial-PNS-MFNG+_DBH+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SHD CELSR3 MANEAL MMP17

3.31e-04188784d3d7d21d4fa39ac4106a164652673de1bef8662d
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

DENND2A FAT4 CCBE1 ANO1

3.38e-0418978444e37f88137bb249933eb615235b2cf2ae7f3925
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GHR FAT4 CCBE1 ABCC9

3.38e-04189784c734e5693808a0333139e87bd5be2597a9252afe
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCBE1 ANO1 ABCC9 SLITRK3

3.44e-041907842e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GHR FAT4 CCBE1 ABCC9

3.44e-04190784445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NR2C1 MAPKBP1 MINDY1 BAHCC1

3.44e-0419078463018acb7ad80415e861643162abdc2e55968ee4
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GHR FAT4 CCBE1 ABCC9

3.44e-041907842e592323085ba9c019d678ac2a784462ab470ed9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCBE1 ANO1 ABCC9 SLITRK3

3.44e-041907840028f886c789ba238c031eae5d96acaed4af8c25
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

SHD KLF12 POU3F4 GNAS

3.44e-04190784842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GHR FAT4 CCBE1 ABCC9

3.51e-04191784cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GHR FAT4 CCBE1 ABCC9

3.51e-04191784c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GHR DENND2A CCBE1 ANO1

3.58e-0419278499ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell(210)_NKT_cell|World / immune cells in Peripheral Blood (logTPM normalization)

BCL9L KLF12 TSPOAP1 PCSK7

3.58e-0419278408dc0c019c594da7b9944db8fd706aa7780e6ae9
ToppCell(21)_NKT_cell|World / immune cells in Peripheral Blood (logTPM normalization)

BCL9L KLF12 TSPOAP1 PCSK7

3.58e-04192784b0a573ddde2978485a857b8261ee1ee5ef68ecef
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

GHR FAT4 COLGALT2 MN1

3.58e-04192784e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCellwk_15-18-Epithelial-PNS-FGFBP2+_Neural_progenitor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SHD CACNB1 ZSWIM4 MMP17

3.58e-04192784ab54d4bfc61ef7e3d765afe6e4a6d7011a301ecd
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UBE2H CCBE1 FBXO11 VCL

3.58e-041927846bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GHR CCBE1 ANO1 ABCC9

3.65e-04193784f1199518c3626fd29bfce65070dd21a660671213
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GHR UBE2H CCBE1 VCL

3.65e-04193784cf3cbf79ccd34ddcf06ec6194a18a7afd7f91f39
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

GHR DENND2A FAT4 CCBE1

3.65e-04193784acad568621ed677031797b8c2e34dafea798d681
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

GHR DENND2A CCBE1 ANO1

3.65e-04193784b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GHR FAT4 COLGALT2 MN1

3.73e-04194784439d3f17c1f4736122b330e98add9292c7036a8e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GHR CCBE1 ANO1 ABCC9

3.80e-04195784d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GHR CCBE1 ABCC9 VCL

3.80e-04195784803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GHR CCBE1 ABCC9 VCL

3.80e-041957844f70157d42a16ff0259bc24a62803c4df4285c44
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A FAT4 CCBE1 MN1

3.95e-041977840dd71e399f253787fa546a7e90c5373180b89ffd
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GHR CCBE1 ANO1 ABCC9

3.95e-041977846d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCBE1 ANO1 ABCC9 VCL

3.95e-0419778480e153790cef37b743e22a7370ff5b3a6abf147d
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KLF12 CCBE1 SLITRK3 MN1

3.95e-04197784ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA13 CCBE1 ANO1 GNAS

3.95e-04197784c7b33d64e5cba3a8fc6f2d6aa85ebc83893195de
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FAT4 TSPOAP1 GAB3 COLGALT2

3.95e-04197784bc37b8919f98dc18c2200834405f06823d965d78
ToppCellTCGA-Skin-Metastatic-Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

KLF12 PLCL2 ABCC9 POMK

4.02e-04198784af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

KLF12 PLCL2 ABCC9 POMK

4.02e-0419878462cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCell3'-GW_trimst-1-LargeIntestine|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA13 CCBE1 ANO1 GNAS

4.02e-04198784ea6621a148a96c8ffa1a93a35c9e288545d2637a
ToppCellTCGA-Skin-Metastatic|TCGA-Skin / Sample_Type by Project: Shred V9

KLF12 PLCL2 ABCC9 POMK

4.02e-04198784ad39cce004867f083f8da1954e0cf5a263815184
ToppCellFetal_29-31_weeks-Mesenchymal|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GHR DENND2A FAT4 CCBE1

4.02e-0419878421cf4d81386761d09d0f6829c01c198e5524176d
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

GHR DENND2A FAT4 CCBE1

4.10e-041997844bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GHR DENND2A FAT4 CCBE1

4.18e-04200784b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GHR DENND2A CCBE1 ANO1

4.18e-04200784cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GHR DENND2A FAT4 CCBE1

4.18e-04200784cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte|Control_saline / Treatment groups by lineage, cell group, cell type

DENND2A ABCC9 MMP17 VCL

4.18e-04200784cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DENND2A ANO1 ABCC9 VCL

4.18e-04200784f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GHR DENND2A CCBE1 ANO1

4.18e-04200784311fab076f2ceb258e3970eb21e39344b894042a
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_only / Treatment groups by lineage, cell group, cell type

DENND2A ANO1 ABCC9 MMP17

4.18e-0420078469edc375d85689300d1dbc1217fedc40063ecdcb
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GHR DENND2A CCBE1 ANO1

4.18e-0420078434f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

GHR ANO1 ABCC9 VCL

4.18e-04200784c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GHR DENND2A FAT4 ABCC9

4.18e-042007840c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal|GW12 / Sample Type, Dataset, Time_group, and Cell type.

SHD DNAH10 PLCL2 MINDY1

4.18e-04200784be83f442179ba4217d12f0458059586ff3130991
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

DENND2A SETD2 STAG1 CREBBP EP300 SMAD1 RUFY3

2.83e-061807876886_DN
DrugGabazine [105538-73-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A

CYP1A2 DENND2A CACNB1 COLGALT2 GNAS PAK6 VCL

5.66e-062007874820_UP
DiseaseAdenoid Cystic Carcinoma

SETD2 MORF4L1 PRKDC CREBBP EP300

6.58e-06100775C0010606
DiseaseMenke-Hennekam syndrome

CREBBP EP300

6.72e-062772cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

6.72e-062772DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

6.72e-062772cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

6.72e-062772C4551859
DiseaseHENNEKAM LYMPHANGIECTASIA-LYMPHEDEMA SYNDROME 1

FAT4 CCBE1

6.72e-062772C4012050
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

6.72e-062772180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

6.72e-062772cv:C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

6.72e-062772DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

6.72e-062772C0035934
DiseaseSmall cell carcinoma of lung

PAK6 POMK CREBBP EP300

1.23e-0554774C0149925
DiseasePrecursor Cell Lymphoblastic Leukemia Lymphoma

CYP1A2 SETD2 CREBBP EP300

2.00e-0561774C1961102
DiseaseHennekam syndrome (is_implicated_in)

FAT4 CCBE1

2.01e-053772DOID:0060366 (is_implicated_in)
DiseaseHennekam lymphangiectasia-lymphedema syndrome

FAT4 CCBE1

2.01e-053772C0340834
Diseasecongenital heart disease (biomarker_via_orthology)

GATA4 DNMT1

4.02e-054772DOID:1682 (biomarker_via_orthology)
Diseasehepatocyte growth factor-like protein measurement

CELSR3 SHISA5 NICN1

1.35e-0438773EFO_0008154
Diseasethioredoxin domain-containing protein 12 measurement

CELSR3 SHISA5 NICN1

1.46e-0439773EFO_0008298
Diseaseclear cell renal cell carcinoma (is_implicated_in)

SETD2 PAK6

1.86e-048772DOID:4467 (is_implicated_in)
DiseaseIGF-1 measurement

GHR METAP1 STAG1 CCBE1 GNAS MAPK8IP3 DNMT1

2.87e-04488777EFO_0004627
DiseaseSquamous cell carcinoma

CYP1A2 PRKDC CREBBP EP300

3.17e-04124774C0007137
DiseaseDiffuse Large B-Cell Lymphoma

FBXO11 CREBBP EP300

4.07e-0455773C0079744
Diseasemonocyte count

SETD2 UBE2H STAG1 TSPOAP1 CECR2 U2SURP PLCL2 PRKDC ONECUT1 MN1 DNMT1

6.11e-0413207711EFO_0005091
DiseaseLeukemia, Myelocytic, Acute

SETD2 MN1 CREBBP EP300

1.11e-03173774C0023467
Diseasehydrocephalus (implicated_via_orthology)

POMK AK8

1.12e-0319772DOID:10908 (implicated_via_orthology)
DiseaseIntellectual Disability

SETD2 STAG1 CCBE1 GNAS MN1 MAPK8IP3

1.12e-03447776C3714756
DiseaseProstatic Neoplasms

GHR SETD2 PRKDC BCAR1 PAK6 CREBBP DNMT1

1.14e-03616777C0033578
DiseaseMalignant neoplasm of prostate

GHR SETD2 PRKDC BCAR1 PAK6 CREBBP DNMT1

1.14e-03616777C0376358
Diseasegastric ulcer

PLCL2 GNAS

1.37e-0321772EFO_0009454
DiseaseATRIAL FIBRILLATION, FAMILIAL, 1 (disorder)

GATA4 ABCC9

1.50e-0322772C1843687
Diseasebasophil count

SETD2 TSPOAP1 RBBP5 PLCL2 ANO1 PRKDC

1.66e-03483776EFO_0005090
Diseasetestosterone measurement

METAP1 STAG1 CECR2 NTAQ1 NICN1 GATA4 FBXO11 FOXN3 ONECUT1 MGRN1

1.73e-0312757710EFO_0004908
Diseaselymphocyte percentage of leukocytes

KLF12 SETD2 TSPOAP1 CECR2 PLCL2 GAB3 PRKDC

1.76e-03665777EFO_0007993
Diseaseosteoarthritis, hip

PLCL2 COLGALT2 EP300

1.82e-0392773EFO_1000786
Diseasealbuminuria

CYP1A2 MAPKBP1 BAHCC1

1.93e-0394773EFO_0004285
Diseaseresponse to interferon

RTN4 ABCC9

1.94e-0325772EFO_0007859
DiseaseSquamous cell carcinoma of esophagus

FAT4 CREBBP EP300

1.99e-0395773C0279626
Diseasehearing impairment

POU3F4 MN1 DNMT1

2.17e-0398773C1384666
DiseaseColorectal Carcinoma

CYP1A2 CACNB1 RTN4 GATA4 GNAS PAK6 EP300

2.38e-03702777C0009402
DiseaseIniencephaly

CYP1A2 CECR2

2.43e-0328772C0152234
DiseaseTethered Cord Syndrome

CYP1A2 CECR2

2.43e-0328772C0080218
DiseaseSpinal Cord Myelodysplasia

CYP1A2 CECR2

2.43e-0328772C0344479
DiseaseExencephaly

CYP1A2 CECR2

2.43e-0328772C0266453
DiseaseNeurenteric Cyst

CYP1A2 CECR2

2.43e-0328772C0027806
DiseaseAcrania

CYP1A2 CECR2

2.43e-0328772C0702169
DiseaseDiastematomyelia

CYP1A2 CECR2

2.43e-0328772C0011999
Diseaseobsolete_red blood cell distribution width

RBBP5 SHISA5 MORF4L1 NICN1 RTN4 U2SURP PLCL2 ZCCHC2 EP300 SMAD1

2.58e-0313477710EFO_0005192
DiseaseCraniorachischisis

CYP1A2 CECR2

2.61e-0329772C0152426

Protein segments in the cluster

PeptideGeneStartEntry
MHVQEYGSDCPPPNQ

EP300

1376

Q09472
MAGRPHPYDGNSSDP

BTBD10

1

Q9BSF8
EGTMAPDHAAPYGVS

BAHCC1

426

Q9P281
EPMEAQTHAPGPYAD

CDRT15L2

81

A8MXV6
EHASMHEYPGELGQP

CACNB1

461

Q02641
KYGQHPPDAVDEPQM

DNMT1

366

P26358
QDIYQVPPSAGMGHD

BCAR1

176

P56945
FDDPDNIPPYGDDMT

FAT4

4556

Q6V0I7
GMHVQEYGSDCPPPN

CREBBP

1411

Q92793
ENYEGTMDPSQVPEH

ABCC9

1291

O60706
PYEHCEPSTMPGDLG

AMPD2

306

Q01433
PDFPESSEIPPSHMY

CECR2

766

Q9BXF3
EIPDGPPVVAHYDMS

C18orf25

236

Q96B23
AQLHGMEDPTQPDYE

PRODH2

391

Q9UF12
PSPMPEYLNVHYIGE

NR2C1

381

P13056
YDPVSMSPNPDAGEE

TSPOAP1

1636

O95153
LQELMAGPGHFDPYN

CYP1A2

176

P05177
VPHYAAIEPDGNGLM

NUDCD1

231

Q96RS6
ADHPDAPMSQVYGAP

MORF4L1

286

Q9UBU8
YLNMPPVDIDGCHSP

ANKRD34B

166

A5PLL1
DGEPPYFSDSPVQAM

PAK6

596

Q9NQU5
PDYADHPLGMSESEQ

METAP1

106

P53582
YPPGEMFLDSDVNPE

MAPK8IP3

821

Q9UPT6
HRAPPKINPDNYGMD

INCENP

811

Q9NQS7
GPHCSPDDYIPMNSG

GAB3

406

Q8WWW8
TPHPEGYLFGENMDL

MGRN1

46

O60291
PPEMPQYGEENHIFE

AK8

11

Q96MA6
SYDLNSNDPDPMPHP

PCSK7

206

Q16549
GLPHYAHPGAAMPTD

ONECUT1

196

Q9UBC0
MEYHQPEDPAPGKAG

MINDY1

1

Q8N5J2
AYSGHDGSPEMQPAP

NSMF

51

Q6X4W1
ASLDAGSGEPPMDYH

ANO1

106

Q5XXA6
YGPPPDAVQTSLMDE

RBBP5

416

Q15291
MTPPGDQQPHEVYSH

POU3F4

336

P49335
HGDRAPLASYPMDPH

ACP4

41

Q9BZG2
AMAANHGPPPGAYEA

GATA4

6

P43694
PPMKENPYEDIELHG

DENND2A

376

Q9ULE3
TGEHVPGSEMPVPDY

GHR

581

P10912
MHPEPGKFYQINPEE

FBXO11

211

Q86XK2
DDDTPPSPAHSDMPY

FOXN3

91

O00409
PSPAHSDMPYDARQN

FOXN3

96

O00409
SYPEAMDLGSGDDHP

CCBE1

376

Q6UXH8
LQQHYPSGMALPPED

BCL9L

1251

Q86UU0
PAHDAGDNNIYEVMP

CEACAM19

231

Q7Z692
YPPGMADDNGEPSDD

MANEAL

191

Q5VSG8
EDGIVYPEPSDNPTM

MAPKBP1

951

O60336
GSPNVHNYPDMEAVP

KLF12

41

Q9Y4X4
AVDPDEGPNAHIMYQ

CELSR3

1091

Q9NYQ7
MDEPESYPDEIGPKH

COLGALT2

121

Q8IYK4
SHPGYEAAMADRPQP

FMR1NB

41

Q8N0W7
HESDLPPMPGEAVEY

DNAH10

176

Q8IVF4
MEGNGPAAVHYQPAS

NTAQ1

1

Q96HA8
PLPMHPAAEDNYGYD

NUP88

296

Q99567
QPPFAEGYEHMAESQ

MN1

146

Q10571
HEPENPPPYEEAMSV

RTN4

651

Q9NQC3
TPDPEPTHEDPNYLM

RUFY3

51

Q7L099
DAQPHPAPPDDGYME

SHD

111

Q96IW2
DHTRHMDPGYPAQSP

MMP17

456

Q9ULZ9
HGSYSPPPEEAMPFE

GNAS

91

Q5JWF2
DGPDNEPVIYTGHTM

PLCL2

476

Q9UPR0
HPPGMQYPDLQQDAR

SLITRK3

916

O94933
YCLMPDPHSEEGAQE

NICN1

81

Q9BSH3
AQPMGPPAYHETLAG

SHISA5

201

Q8N114
PYGEDVPFHDDLMPS

POMK

261

Q9H5K3
HPEDMDPSDNYAEPI

ARHGAP5

1081

Q13017
NVSPYMEYHPGGEDE

CYB5R4

81

Q7L1T6
MAHPAPLAPGAASAY

HOXA13

91

P31271
AYLPPEDPMTQDGSQ

SMAD1

226

Q15797
PPLNPYLHGMSEEQE

U2SURP

506

O15042
PQTPYANGLVHDPVM

ZCCHC2

1076

Q9C0B9
DSLTQPDEEPMHYGN

RSPH3

176

Q86UC2
PNPIDPLNGDAAAMY

UBE2H

116

P62256
PSPPYHSMMGDDEDA

PPP1R2B

71

Q6NXS1
AAGFPVPPDMEDDYE

VCL

936

P18206
DEDSGDYPLTMPGPQ

STAG1

156

Q8WVM7
KMGDFYDPEHPTPEE

SETD2

11

Q9BYW2
DYPNPMFEHPLSECE

PRKDC

2571

P78527
DPLVYNMSHEDPGNV

PSMC6

116

P62333
SILHAPGDDPMGYES

UBE2G2

91

P60604
MYSSLGYPPPEGEHD

ZSWIM4

81

Q9H7M6