Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	EXOSC10 MCM8 ATRX TDRD9 TYW1B DDX20 POLN PTBP1 DICER1 POLR3A	4.16e-05	645	65	10	GO:0140640
GeneOntologyMolecularFunction	helicase activity	MCM8 ATRX TDRD9 DDX20 DICER1	1.64e-04	158	65	5	GO:0004386
Domain	Histone_H5	H1-2 H1-4	3.19e-04	8	64	2	IPR005819
Domain	Helicase_C	ATRX TDRD9 DDX20 DICER1	4.97e-04	107	64	4	PF00271
Domain	HELICc	ATRX TDRD9 DDX20 DICER1	4.97e-04	107	64	4	SM00490
Domain	Helicase_C	ATRX TDRD9 DDX20 DICER1	5.14e-04	108	64	4	IPR001650
Domain	HELICASE_CTER	ATRX TDRD9 DDX20 DICER1	5.33e-04	109	64	4	PS51194
Domain	HELICASE_ATP_BIND_1	ATRX TDRD9 DDX20 DICER1	5.33e-04	109	64	4	PS51192
Domain	DEXDc	ATRX TDRD9 DDX20 DICER1	5.33e-04	109	64	4	SM00487
Domain	Helicase_ATP-bd	ATRX TDRD9 DDX20 DICER1	5.51e-04	110	64	4	IPR014001
Domain	H15	H1-2 H1-4	8.80e-04	13	64	2	SM00526
Domain	Linker_histone	H1-2 H1-4	8.80e-04	13	64	2	PF00538
Domain	H15	H1-2 H1-4	8.80e-04	13	64	2	PS51504
Domain	Histone_H1/H5_H15	H1-2 H1-4	1.02e-03	14	64	2	IPR005818
Domain	P_typ_ATPase_c	ATP8A1 ATP8B2	1.02e-03	14	64	2	IPR032630
Domain	P-type_ATPase_N	ATP8A1 ATP8B2	1.02e-03	14	64	2	IPR032631
Domain	P-type_ATPase_IV	ATP8A1 ATP8B2	1.02e-03	14	64	2	IPR006539
Domain	PhoLip_ATPase_C	ATP8A1 ATP8B2	1.02e-03	14	64	2	PF16212
Domain	PhoLip_ATPase_N	ATP8A1 ATP8B2	1.02e-03	14	64	2	PF16209
Domain	DEAD/DEAH_box_helicase_dom	TDRD9 DDX20 DICER1	2.01e-03	73	64	3	IPR011545
Domain	DEAD	TDRD9 DDX20 DICER1	2.01e-03	73	64	3	PF00270
Domain	-	CACNB2 MCM8 ATRX TDRD9 DDX20 HNRNPUL1 DNAH7 DICER1	3.83e-03	746	64	8	3.40.50.300
Domain	TUDOR	TDRD9 ARID4A	3.84e-03	27	64	2	SM00333
Domain	Tudor	TDRD9 ARID4A	4.73e-03	30	64	2	IPR002999
Domain	-	ATP8A1 ATP8B2	5.37e-03	32	64	2	3.40.1110.10
Domain	-	ATP8A1 ATP8B2	5.37e-03	32	64	2	2.70.150.10
Domain	ATPase_P-typ_cyto_domN	ATP8A1 ATP8B2	6.39e-03	35	64	2	IPR023299
Domain	P_typ_ATPase	ATP8A1 ATP8B2	6.76e-03	36	64	2	IPR001757
Domain	ATPase_P-typ_P_site	ATP8A1 ATP8B2	6.76e-03	36	64	2	IPR018303
Domain	ATPASE_E1_E2	ATP8A1 ATP8B2	6.76e-03	36	64	2	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP8A1 ATP8B2	7.13e-03	37	64	2	IPR008250
Domain	E1-E2_ATPase	ATP8A1 ATP8B2	7.13e-03	37	64	2	PF00122
Domain	P-loop_NTPase	CACNB2 MCM8 ATRX TDRD9 DDX20 HNRNPUL1 DNAH7 DICER1	8.16e-03	848	64	8	IPR027417
Domain	Laminin_G_2	COL11A1 NRXN2	8.29e-03	40	64	2	PF02210
Domain	LamG	COL11A1 NRXN2	9.97e-03	44	64	2	SM00282
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SYNRG ATRX ARID4A DDX20 BRD3 HNRNPUL1 ANXA9 TOPORS PRRC2A PHLDB2	1.67e-06	774	65	10	15302935
Pubmed	CRL4DCAF8 dependent opposing stability control over the chromatin remodeler LSH orchestrates epigenetic dynamics in ferroptosis.	H1-2 H1-4 WDR76	3.43e-06	16	65	3	33288900
Pubmed	Dynamics and dispensability of variant-specific histone H1 Lys-26/Ser-27 and Thr-165 post-translational modifications.	H1-2 H1-4	3.44e-06	2	65	2	24873882
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	EXOSC10 H1-2 DDX20 HNRNPUL1 PTBP1 PRRC2A	6.55e-06	244	65	6	29884807
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	CEP350 EXOSC10 COL11A1 UBAP2 PEG3 PKP2 APOB DDX20 PTBP1 WDR76 PRRC2A DICER1	7.81e-06	1371	65	12	36244648
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	CACNG2 SYNRG NEO1 UBAP2 EEF1E1 H1-2 H1-4 PLCB1 RTN3 PTBP1 SACM1L	7.85e-06	1139	65	11	36417873
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	SYNRG EXOSC10 UBAP2 ATRX SH3D19 RNF113A H1-4 HNRNPUL1 PRRC2A WAC	8.74e-06	934	65	10	33916271
Pubmed	Quantitative Mass Spectrometry Reveals that Intact Histone H1 Phosphorylations are Variant Specific and Exhibit Single Molecule Hierarchical Dependence.	H1-2 H1-4	1.03e-05	3	65	2	26209608
Pubmed	High-resolution mapping of h1 linker histone variants in embryonic stem cells.	H1-2 H1-4	1.03e-05	3	65	2	23633960
Pubmed	The rhox homeobox gene cluster is imprinted and selectively targeted for regulation by histone h1 and DNA methylation.	H1-2 H1-4	1.03e-05	3	65	2	21245380
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	EXOSC10 UBAP2 ATRX ARID4A EEF1E1 H1-2 HNRNPUL1 PTBP1 PRRC2A WAC	1.05e-05	954	65	10	36373674
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	UBAP2 DIAPH2 HNRNPUL1 PTBP1 POLR3A	1.06e-05	154	65	5	16055720
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	CEP350 EXOSC10 NEO1 H1-4 PKP2 APOB HNRNPUL1 PTBP1 DNAH7	1.38e-05	777	65	9	35844135
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	EXOSC10 UBAP2 EEF1E1 H1-2 PKP2 HNRNPUL1 PTBP1 PRRC2A	1.90e-05	615	65	8	31048545
Pubmed	Increased excitability and inward rectification in layer V cortical pyramidal neurons in the epileptic mutant mouse Stargazer.	CACNG2 KRT71	2.06e-05	4	65	2	9065835
Pubmed	H1 linker histones are essential for mouse development and affect nucleosome spacing in vivo.	H1-2 H1-4	2.06e-05	4	65	2	12808097
Pubmed	Distribution of somatic H1 subtypes is non-random on active vs. inactive chromatin II: distribution in human adult fibroblasts.	H1-2 H1-4	2.06e-05	4	65	2	11746507
Pubmed	The distribution of somatic H1 subtypes is non-random on active vs. inactive chromatin: distribution in human fetal fibroblasts.	H1-2 H1-4	2.06e-05	4	65	2	10997781
Pubmed	Individual somatic H1 subtypes are dispensable for mouse development even in mice lacking the H1(0) replacement subtype.	H1-2 H1-4	2.06e-05	4	65	2	11689686
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	CEP350 TDRD9 H1-2 AIRE PKP2 PRRC2A DICER1 PHLDB2	2.50e-05	639	65	8	23443559
Pubmed	Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6.	H1-2 H1-4 HNRNPUL1 PTBP1	2.52e-05	90	65	4	23151878
Pubmed	Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression.	H1-2 H1-4 HNRNPUL1 PTBP1	2.52e-05	90	65	4	33087562
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	EXOSC10 ATRX ARID4A EEF1E1 H1-2 H1-4 BRD3 HNRNPUL1 PTBP1 WDR76 WAC	2.56e-05	1294	65	11	30804502
Pubmed	TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.	ARID4A EEF1E1 H1-2 H1-4 HNRNPUL1 PTBP1	2.87e-05	317	65	6	30997501
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	EEF1E1 RNF113A H1-2 H1-4 HNRNPUL1 PTBP1 PRRC2A DICER1	2.98e-05	655	65	8	35819319
Pubmed	The mouse histone H1 genes: gene organization and differential regulation.	H1-2 H1-4	3.43e-05	5	65	2	9300059
Pubmed	A compendium of the histone H1 family of somatic subtypes: an elusive cast of characters and their characteristics.	H1-2 H1-4	3.43e-05	5	65	2	11467742
Pubmed	Nuclear particles containing RNA polymerase III complexes associated with the junctional plaque protein plakophilin 2.	PKP2 POLR3A	3.43e-05	5	65	2	11416169
Pubmed	A proposal for a coherent mammalian histone H1 nomenclature correlated with amino acid sequences.	H1-2 H1-4	3.43e-05	5	65	2	8003976
Pubmed	Characterization of the histone H1-binding protein, NASP, as a cell cycle-regulated somatic protein.	H1-2 H1-4	3.43e-05	5	65	2	10893414
Pubmed	The pathological consequences of impaired genome integrity in humans; disorders of the DNA replication machinery.	MCM8 CDC7	3.43e-05	5	65	2	27757957
Pubmed	Expression of murine H1 histone genes during postnatal development.	H1-2 H1-4	3.43e-05	5	65	2	9655912
Pubmed	Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.	EXOSC10 H1-4 DDX20 HNRNPUL1 PTBP1 PRRC2A	3.78e-05	333	65	6	36779763
Pubmed	Circular RNA FOXP1 promotes tumor progression and Warburg effect in gallbladder cancer by regulating PKLR expression.	TYW1B H1-4 HNRNPUL1 PTBP1	4.11e-05	102	65	4	31623628
Pubmed	Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in mice.	NEO1 SH3D19 CDH18	4.63e-05	37	65	3	16707424
Pubmed	Characterization of phosphorylation sites on histone H1 isoforms by tandem mass spectrometry.	H1-2 H1-4	5.13e-05	6	65	2	15595731
Pubmed	The preferential binding of histone H1 to DNA scaffold-associated regions is determined by its C-terminal domain.	H1-2 H1-4	5.13e-05	6	65	2	15562002
Pubmed	The multifunctional protein nucleophosmin (NPM1) is a human linker histone H1 chaperone.	H1-2 H1-4	5.13e-05	6	65	2	21425800
Pubmed	Hormone-mediated dephosphorylation of specific histone H1 isoforms.	H1-2 H1-4	5.13e-05	6	65	2	11479299
Pubmed	Linker histone transitions during mammalian oogenesis and embryogenesis.	H1-2 H1-4	5.13e-05	6	65	2	9499577
Pubmed	Histone H1 recruitment by CHD8 is essential for suppression of the Wnt-β-catenin signaling pathway.	H1-2 H1-4	5.13e-05	6	65	2	22083958
Pubmed	H1 family histones in the nucleus. Control of binding and localization by the C-terminal domain.	H1-2 H1-4	5.13e-05	6	65	2	15911621
Pubmed	Stargazer: a new neurological mutant on chromosome 15 in the mouse with prolonged cortical seizures.	CACNG2 KRT71	5.13e-05	6	65	2	2289471
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	EXOSC10 GID4 EEF1E1 AGPAT4 DDX20 HNRNPUL1 PTBP1 PRRC2A DICER1 POLR3A SACM1L	6.75e-05	1440	65	11	30833792
Pubmed	Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma.	H1-2 H1-4	7.18e-05	7	65	2	24435047
Pubmed	CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery.	ATP8A1 ATP8B2	7.18e-05	7	65	2	20961850
Pubmed	Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases.	ATP8A1 ATP8B2	7.18e-05	7	65	2	20947505
Pubmed	All known human H1 histone genes except the H1(0) gene are clustered on chromosome 6.	H1-2 H1-4	7.18e-05	7	65	2	8325638
Pubmed	A genome-wide association study of early menopause and the combined impact of identified variants.	MCM8 PRRC2A	7.18e-05	7	65	2	23307926
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	CACNG2 ATRX H1-4 RTN3 PRRC2A	7.39e-05	231	65	5	16452087
Pubmed	Large-scale concatenation cDNA sequencing.	CEP350 ATP8A1 DDX20 BRD3 RUNX1T1 ZNF804A DICER1	9.17e-05	568	65	7	9110174
Pubmed	Histone h1 depletion impairs embryonic stem cell differentiation.	H1-2 H1-4	9.56e-05	8	65	2	22589736
Pubmed	Black carbon exposures, blood pressure, and interactions with single nucleotide polymorphisms in MicroRNA processing genes.	DDX20 DICER1	9.56e-05	8	65	2	20211803
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	ATRX H1-2 BRD3 HNRNPUL1 WDR76 PRRC2A	9.57e-05	394	65	6	27248496
Pubmed	A "double adaptor" method for improved shotgun library construction.	CEP350 ATP8A1 DDX20 BRD3 RUNX1T1 ZNF804A DICER1	9.78e-05	574	65	7	8619474
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	EEF1E1 H1-2 H1-4 PKP2 HNRNPUL1 PTBP1 TOPORS PRRC2A PHLDB2 SACM1L	1.01e-04	1247	65	10	27684187
Pubmed	Intrinsically Disordered Protein TEX264 Mediates ER-phagy.	SYNRG RTN3 HNRNPUL1 PRRC2A	1.09e-04	131	65	4	31006538
Pubmed	Substrate specificity analysis and novel substrates of the protein lysine methyltransferase NSD1.	ATRX H1-2	1.23e-04	9	65	2	24412544
Pubmed	Developmentally regulated linker histone H1c promotes heterochromatin condensation and mediates structural integrity of rod photoreceptors in mouse retina.	H1-2 H1-4	1.23e-04	9	65	2	23645681
Pubmed	Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop.	UBAP2 PKP2 HNRNPUL1 PTBP1 PHLDB2	1.29e-04	260	65	5	36199071
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CEP350 ATRX OTOF SH3D19 PEG3 AIRE HNRNPUL1 PRRC2A ZNF181 WAC	1.29e-04	1285	65	10	35914814
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	CEP350 PEG3 PTBP1 RUNX1T1 ZNF804A PRRC2A WAC	1.40e-04	608	65	7	16713569
Pubmed	Analysis of HIV-1 Gag protein interactions via biotin ligase tagging.	UBAP2 H1-2 PRRC2A	1.44e-04	54	65	3	25631074
Pubmed	The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease.	ATP8A1 ATP8B2	1.53e-04	10	65	2	15919184
Pubmed	Dynamic changes in H1 subtype composition during epigenetic reprogramming.	H1-2 H1-4	1.53e-04	10	65	2	28794128
Pubmed	High-throughput kinase assays with protein substrates using fluorescent polymer superquenching.	H1-2 H1-4	1.53e-04	10	65	2	15927069
Pubmed	Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells.	DDX20 HNRNPUL1 DICER1	1.70e-04	57	65	3	17932509
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	EXOSC10 UBAP2 ATRX PKP2 HNRNPUL1 DICER1	1.74e-04	440	65	6	34244565
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	EXOSC10 EEF1E1 PEG3 H1-2 H1-4 HNRNPUL1 PTBP1 PRRC2A DICER1 POLR3A	1.76e-04	1335	65	10	29229926
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	EXOSC10 ATRX H1-2 H1-4 PTBP1 PRRC2A	1.76e-04	441	65	6	31239290
Pubmed	Genomic imprinting in Dicer1-hypomorphic mice.	PEG3 DICER1	1.87e-04	11	65	2	16575173
Pubmed	The proteomic investigation of chromatin functional domains reveals novel synergisms among distinct heterochromatin components.	H1-2 H1-4	1.87e-04	11	65	2	23319141
Pubmed	Role of H1 linker histones in mammalian development and stem cell differentiation.	H1-2 H1-4	1.87e-04	11	65	2	26689747
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CEP350 SYNRG UBAP2 SH3D19 PKP2 HNRNPUL1 DNAH7 PHLDB2	1.98e-04	861	65	8	36931259
Pubmed	MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer.	EEF1E1 H1-2 H1-4 APOB PTBP1	2.04e-04	287	65	5	36180891
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	MCM8 ATRX H1-4 DIAPH2 DICER1 POLR3A SACM1L	2.10e-04	650	65	7	38777146
Pubmed	Interaction of human minichromosome maintenance protein-binding protein with minichromosome maintenance 2-7.	MCM8 CDC7	2.24e-04	12	65	2	24299456
Pubmed	A unified phylogeny-based nomenclature for histone variants.	H1-2 H1-4	2.24e-04	12	65	2	22650316
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	DDX20 BRD3 HNRNPUL1 DICER1 POLR3A	2.50e-04	300	65	5	28561026
Pubmed	Differential expression of putative transbilayer amphipath transporters.	ATP8A1 ATP8B2	2.65e-04	13	65	2	11015572
Pubmed	Interactions of the human MCM-BP protein with MCM complex components and Dbf4.	MCM8 CDC7	2.65e-04	13	65	2	22540012
Pubmed	Characterization of the mouse histone gene cluster on chromosome 13: 45 histone genes in three patches spread over 1Mb.	H1-2 H1-4	2.65e-04	13	65	2	8858344
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	EXOSC10 H1-4 PKP2 DDX20 HNRNPUL1 PTBP1 PRRC2A	2.71e-04	678	65	7	30209976
Pubmed	Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS.	ARID4A SH3D19 DICER1	2.86e-04	68	65	3	36966392
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	ATRX H1-2 RTN3 APOB DDX20 HNRNPUL1 PTBP1 DICER1 POLR3A SACM1L	2.97e-04	1425	65	10	30948266
Pubmed	ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.	UBAP2 PKP2 HNRNPUL1 PRRC2A PHLDB2	3.13e-04	315	65	5	26777405
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	H1-2 HNRNPUL1 WDR76 PRRC2A PHLDB2	3.41e-04	321	65	5	32098917
Pubmed	Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis.	H1-2 H1-4	3.56e-04	15	65	2	28784777
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	EXOSC10 H1-2 PKP2 DDX20 HNRNPUL1 PTBP1 PRRC2A	3.67e-04	713	65	7	29802200
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	H1-2 H1-4 PKP2 C1QB APOB DDX20 HNRNPUL1 PTBP1	3.81e-04	949	65	8	36574265
Pubmed	Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance.	ATRX H1-2	4.06e-04	16	65	2	25416818
Pubmed	Histone H3.3 maintains genome integrity during mammalian development.	ATRX ZNF804A	4.06e-04	16	65	2	26159997
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNG2 CACNB2 UBAP2 SH3D19 DIAPH2 PLCB1 PRRC2A PHLDB2	4.20e-04	963	65	8	28671696
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	EXOSC10 EEF1E1 H1-2 H1-4 HNRNPUL1 PTBP1 PRRC2A	4.26e-04	731	65	7	29298432
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	ATP8A1 PLCB1 RTN3 PRRC2A ADCY5	4.86e-04	347	65	5	17114649
Pubmed	A physical interaction network of dengue virus and human proteins.	APOB PTBP1	5.16e-04	18	65	2	21911577
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	EXOSC10 UBAP2 DDX20 HNRNPUL1 PTBP1 PRRC2A	5.76e-04	551	65	6	34728620
Pubmed	Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.	MCM8 PRRC2A	5.76e-04	19	65	2	22267201
Pubmed	Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures.	MCM8 CDC7	5.76e-04	19	65	2	15226314
Pubmed	Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is required for proper replication restart and cellular resistance to replication stress.	ATRX H1-2	5.76e-04	19	65	2	23329831
GeneFamily	X-linked mental retardation\|RNA helicases	ATRX DICER1	3.28e-04	11	45	2	1168
GeneFamily	ATPase phospholipid transporting	ATP8A1 ATP8B2	6.23e-04	15	45	2	1210
GeneFamily	Calcium voltage-gated channel subunits	CACNG2 CACNB2	1.90e-03	26	45	2	253
ToppCell	NS-critical-LOC-Lymphoid-NK\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ATP8A1 AGPAT4 H1-4 PLCB1 PHLDB2 SACM1L	1.89e-07	171	65	6	adda76991d9b150bb8ccf3989b7cbbf41843cf0b
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 ATRX PEG3 H1-4 HNRNPUL1	5.91e-06	176	65	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	wk_08-11-Epithelial-PNS-FGFBP2+_Neural_progenitor\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ATP8A1 CYP11A1 AIRE PKP2 ZNF804A	6.08e-06	177	65	5	15a5c96ea840376e54933ebe7a8334a11d9ce411
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 PRSS12 PEG3 PLCB1 RUNX1T1	7.53e-06	185	65	5	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 ATRX H1-4 HNRNPUL1 PHLDB2	7.73e-06	186	65	5	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 ATRX H1-4 APOB HNRNPUL1	8.79e-06	191	65	5	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 ATRX H1-4 APOB HNRNPUL1	8.79e-06	191	65	5	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 ATRX H1-4 APOB HNRNPUL1	8.79e-06	191	65	5	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	CEP350 ATRX ARID4A H1-4 PRRC2A	1.02e-05	197	65	5	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2\|World / Primary Cells by Cluster	COL11A1 MCM8 H1-2 H1-4 WDR76	1.10e-05	200	65	5	4923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2-5\|World / Primary Cells by Cluster	COL11A1 MCM8 H1-2 H1-4 WDR76	1.10e-05	200	65	5	dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCell	368C-Fibroblasts-Fibroblast-F-\|368C / Donor, Lineage, Cell class and subclass (all cells)	POLN RUNX1T1 DNAH7 ATP8B2	8.19e-05	157	65	4	982e6ea78c7dabdb7c07c4a5fb2425d5e45b5b94
ToppCell	368C-Fibroblasts-Fibroblast-F\|368C / Donor, Lineage, Cell class and subclass (all cells)	POLN RUNX1T1 DNAH7 ATP8B2	8.19e-05	157	65	4	74038192f016f95f80e0189035ee8ccc22ceb1b8
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D122\|Adult / Lineage, Cell type, age group and donor	CACNB2 NFE4 PLCB1 ADCY5	9.02e-05	161	65	4	64891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL11A1 PRSS12 NFE4 PHLDB2	1.04e-04	167	65	4	cb650f74306fa0d9f4bf49890b73065d193b94dc
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CEP350 H1-2 DNAH7 DICER1	1.11e-04	170	65	4	0f215911b5880eeffeb43230f7eeaf55b612eaf2
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_HSPB3\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL11A1 PRSS12 DNAH7 PHLDB2	1.11e-04	170	65	4	985c6c9e3c593ed0628a481f06c2c91b2ab5d746
ToppCell	droplet-Lung-1m-Hematologic-myeloid-Basophil/Mast_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARID4A CYP11A1 H1-2 POLN	1.19e-04	173	65	4	117163c5cd2b7aaa1c0682c8ac44b4249df4d2f8
ToppCell	droplet-Lung-1m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARID4A CYP11A1 H1-2 POLN	1.19e-04	173	65	4	01df9baeedf30e3a4891738554cdd300394dbb96
ToppCell	NS-moderate-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CACNB2 RUNX1T1 ADCY5 PHLDB2	1.24e-04	175	65	4	a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCM8 RNF113A PKP2 CDC7	1.30e-04	177	65	4	c6812679aa6522d03bd29144e71c5fae6a92325e
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCM8 RNF113A PKP2 CDC7	1.30e-04	177	65	4	ff97398d2adb83063b7c53a264bfae86ea7ea304
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX TDRD9 OTOF AGPAT4	1.30e-04	177	65	4	426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL11A1 PEG3 PLCB1 ATP8B2	1.33e-04	178	65	4	a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL11A1 PRSS12 DNAH7 PHLDB2	1.33e-04	178	65	4	0e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 PRSS12 PEG3 RUNX1T1	1.36e-04	179	65	4	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	T_cells-GZMK+_CD8+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	SYNRG ATP8A1 OTOF C1QB	1.36e-04	179	65	4	798f208014f2229c597934775646ddbbacf94b69
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Syt6\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	IQCH AIRE APOB	1.41e-04	69	65	3	31f4fb56dfa5e3ad7c83e0770960c3617e4f66a7
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Syt6-Excitatory_NeuronSlc17a7-Slc17a6.Syt6-Nnat_(Deep_layer_pyramidal_cells--medial_cortex)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	IQCH AIRE APOB	1.41e-04	69	65	3	de297aa59c70f15c55cb9570439dc6d3fd6c182b
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast\|E18.5-samps / Age Group, Lineage, Cell class and subclass	NEO1 PEG3 DIAPH2 RUNX1T1	1.45e-04	182	65	4	ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCell	wk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL11A1 EEF1E1 PEG3 ATP8B2	1.45e-04	182	65	4	03a5a02acd48f0eb210485348bfe0cd21f486215
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 PRSS12 PEG3 RUNX1T1	1.48e-04	183	65	4	12daaea821e49bc94a01e2496331e92a80d27339
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB2 PRSS12 PEG3 RUNX1T1	1.51e-04	184	65	4	3da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 ATRX DIAPH2 HNRNPUL1	1.54e-04	185	65	4	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 PRSS12 PEG3 RUNX1T1	1.54e-04	185	65	4	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	CACNB2 SH3D19 RUNX1T1 PHLDB2	1.54e-04	185	65	4	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	CACNB2 COL11A1 ADCY5 PHLDB2	1.60e-04	187	65	4	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Striatum / BrainAtlas - Mouse McCarroll V32	OTOF PLCB1 RUNX1T1 ADCY5	1.64e-04	188	65	4	e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	UBAP2 NRXN2 PLCB1 TOPORS	1.67e-04	189	65	4	8e6b6025f5554672e26a5d19fe365acb4333789c
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PEG3 H1-4 PKP2 PHLDB2	1.67e-04	189	65	4	8e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PEG3 H1-4 PKP2 PHLDB2	1.67e-04	189	65	4	fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL11A1 PRSS12 PEG3 CDH18	1.67e-04	189	65	4	d0c7549be4f77520c23dddf4f94d0fcad0081e37
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 PRSS12 PEG3 ADCY5	1.74e-04	191	65	4	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 PEG3 RUNX1T1 ADCY5	1.74e-04	191	65	4	08042952431ca1a6fd7dfc13f36eb28643979598
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 ATRX PEG3 C1QB	1.78e-04	192	65	4	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A1 ATRX PEG3 FOXN3	1.85e-04	194	65	4	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NEO1 PEG3 AGPAT4 RUNX1T1	1.88e-04	195	65	4	cbe518b465b4ef32797ae6b608219207c08493df
ToppCell	PND03-Mesenchymal-Mesenchymal_structural\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NEO1 PEG3 AGPAT4 RUNX1T1	1.88e-04	195	65	4	136b06b0931a69b1241101f68c01c44c70365fd9
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38\|World / Primary Cells by Cluster	ATRX PLCB1 FOXN3 ZNF804A	1.92e-04	196	65	4	38da0751941adca650fe9b383d9f343153978eb5
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	NEO1 PEG3 RUNX1T1 WDR76	1.92e-04	196	65	4	54f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-41\|World / Primary Cells by Cluster	ATRX TDRD9 PRSS12 PKP2	1.92e-04	196	65	4	dee0984cd63a1a2fdebb4421af48ab566a5b684e
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn\|World / Primary Cells by Cluster	ATRX PLCB1 FOXN3 ZNF804A	1.92e-04	196	65	4	721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	ATP8A1 TDRD9 CDH18 MEPE	1.96e-04	197	65	4	6b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	CACNB2 SH3D19 RUNX1T1 PHLDB2	1.96e-04	197	65	4	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	NEO1 SH3D19 FOXN3 RUNX1T1	1.96e-04	197	65	4	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	Control_saline-Epithelial_airway-airway_epithelial\|Control_saline / Treatment groups by lineage, cell group, cell type	IQCH ANXA9 DNAH7 MEPE	2.00e-04	198	65	4	e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell	Control_saline-Epithelial_airway\|Control_saline / Treatment groups by lineage, cell group, cell type	IQCH ANXA9 DNAH7 MEPE	2.00e-04	198	65	4	e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PEG3 PLCB1 RTN3 CDH18	2.00e-04	198	65	4	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PEG3 PLCB1 RTN3 CDH18	2.00e-04	198	65	4	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	COVID-19_Moderate\|World / disease group, cell group and cell class	ATP8A1 ATRX OTOF H1-4	2.04e-04	199	65	4	952fac67588ad5676f5939e3c7f8bac803c27064
ToppCell	LPS_anti-TNF-Epithelial_airway\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	IQCH ANXA9 DNAH7 MEPE	2.04e-04	199	65	4	6aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	IQCH ANXA9 DNAH7 MEPE	2.04e-04	199	65	4	60919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	IQCH TDRD9 OTOF DNAH7	2.08e-04	200	65	4	96701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Interneuron\|2m / Sample Type, Dataset, Time_group, and Cell type.	CACNG2 ARID4A PRSS12 RUNX1T1	2.08e-04	200	65	4	08bee924a2654e05df3b39e8a51f93c8b3472175
Disease	hemoglobin A1 measurement	H1-2 PLCB1 FOXN3 HNRNPUL1 PTBP1 WDR76 ADCY5	1.08e-04	520	62	7	EFO_0007629
Disease	Other specified cardiac arrhythmias	CACNB2 PKP2	2.36e-04	11	62	2	C0348626
Disease	Nodal rhythm disorder	CACNB2 PKP2	2.36e-04	11	62	2	C0264893
Disease	Ectopic rhythm	CACNB2 PKP2	2.36e-04	11	62	2	C1399226
Disease	CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)	CACNB2 PKP2	2.36e-04	11	62	2	C2748542
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	ANKRD31 TYW1B AGPAT4 APOB	2.85e-04	150	62	4	EFO_0004611, EFO_0020947
Disease	Brugada Syndrome 1	CACNB2 PKP2	3.34e-04	13	62	2	C4551804
Disease	Sinus Node Dysfunction (disorder)	CACNB2 PKP2	4.48e-04	15	62	2	C0428908
Disease	Schizophrenia	CACNG2 CACNB2 NRXN2 H1-4 PLCB1 C1QB ZNF804A DICER1	5.05e-04	883	62	8	C0036341
Disease	Colorectal Carcinoma	CACNB2 PEG3 H1-4 APOB RUNX1T1 ZNF804A WAC	6.62e-04	702	62	7	C0009402
Disease	ovulation	MCM8 PRRC2A	7.26e-04	19	62	2	GO_0030728
Disease	liver fibrosis measurement	ANKRD31 APOB HNRNPUL1	7.98e-04	86	62	3	EFO_0010576
Disease	bone density, lean body mass	GID4 MEPE	8.89e-04	21	62	2	EFO_0003923, EFO_0004995
Disease	phosphatidylinositol measurement	PLCB1 APOB FOXN3	1.07e-03	95	62	3	EFO_0010230
Disease	triacylglycerol 54:8 measurement	EEF1E1 PLCB1	1.07e-03	23	62	2	EFO_0010426
Disease	alcohol use disorder measurement	CACNB2 ARID4A RUNX1T1 ZNF804A	1.08e-03	214	62	4	EFO_0009458
Disease	alcohol consumption measurement	BPNT2 ARID4A CYP11A1 PLCB1 BRD3 RUNX1T1 WDR76 ZNF804A CDH18	1.10e-03	1242	62	9	EFO_0007878
Disease	Brugada Syndrome (disorder)	CACNB2 PKP2	1.16e-03	24	62	2	C1142166
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	ANKRD31 TYW1B AGPAT4 APOB	1.24e-03	222	62	4	EFO_0008317, EFO_0020943
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	ANKRD31 TYW1B AGPAT4 APOB	1.30e-03	225	62	4	EFO_0008317, EFO_0020947
Disease	bipolar disorder	CACNB2 UBAP2 IQCH TDRD9 H1-2 ZNF804A	1.32e-03	577	62	6	MONDO_0004985
Disease	cholesterol to total lipids in small LDL percentage	ANKRD31 APOB	1.47e-03	27	62	2	EFO_0022241
Disease	cholesterol to total lipids in medium LDL percentage	ANKRD31 APOB	1.47e-03	27	62	2	EFO_0022238
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipid measurement	TYW1B AGPAT4 APOB	1.58e-03	109	62	3	EFO_0004639, EFO_0008317, EFO_0008596
Disease	aspartate aminotransferase to alanine aminotransferase ratio	ANKRD31 CACNB2 TYW1B ANXA9	1.62e-03	239	62	4	EFO_0010934
Disease	very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	ANKRD31 TYW1B AGPAT4 APOB	1.62e-03	239	62	4	EFO_0008317, EFO_0020945
Disease	cholesteryl ester measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement	TYW1B AGPAT4 APOB	1.62e-03	110	62	3	EFO_0008317, EFO_0008596, EFO_0010351
Disease	free cholesterol measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement	TYW1B AGPAT4 APOB	1.62e-03	110	62	3	EFO_0008317, EFO_0008591, EFO_0008596
Disease	chylomicron measurement, total cholesterol measurement, very low density lipoprotein cholesterol measurement	TYW1B AGPAT4 APOB	1.62e-03	110	62	3	EFO_0004574, EFO_0008317, EFO_0008596
Disease	Hematopoetic Myelodysplasia	ATRX PLCB1	1.70e-03	29	62	2	C2713368
Disease	factor VIII measurement, coronary artery disease	AGPAT4 APOB PRRC2A	1.75e-03	113	62	3	EFO_0001645, EFO_0004630
Disease	omega-3 polyunsaturated fatty acid measurement	COL11A1 TYW1B APOB	1.99e-03	118	62	3	EFO_0010119

Protein segments in the cluster

Peptide	Gene	Start	Entry
KKGGKQASASYDSEE	BRD3	551	Q15059
YGLSKTANSEGKSDS	ARID4A	681	P29374
GGQKSFLYSELSNKS	AKAP4	296	Q5JQC9
DSSGKRSVKFNKGYT	FAM219B	96	Q5XKK7
LKENNGKGYAESGSA	EVX2	136	Q03828
ASGSFKLNKKAASGE	H1-2	101	P16403
QSKGNKSYLEGSSDN	DDX20	666	Q9UHI6
AASGLNDSTYDKVGK	ADCY5	1131	O95622
QYISATAKSGGLKNS	DIAPH2	141	O60879
KYLDGNANKSTSDGS	DICER1	1241	Q9UPY3
KALQYGTAFGNGKTS	ATP8A1	961	Q9Y2Q0
YTPSKFEDSGSGKNK	AIRE	231	O43918
KQGKFYSSKSGGNSS	CACNB2	191	Q08289
VGNGFTYQDKLSSSK	ATP8B2	746	P98198
AEGYLNSGNSGALKK	POLN	181	Q7Z5Q5
KSLNGYKNLSSGAET	NFE4	11	Q86UQ8
YSTKSGGKRVFDSAN	IQCH	606	Q86VS3
AGDPSKSDSKKNSYS	CACNG2	161	Q9Y698
STGGKKHYNFKENLT	ANKRD31	921	Q8N7Z5
YFGKKASGNSNKESL	PRSS12	601	P56730
LALFGGSQKYADDKN	MCM8	426	Q9UJA3
EASENKGSSKSQNYF	MEPE	76	Q9NQ76
YSDAEDLKKGGGSSS	RUNX1T1	396	Q06455
NSKGSDTAYRVSKQA	COL11A1	66	P12107
GKSADYVNLSLKSGA	NRXN2	331	Q9P2S2
FGKSLYSSLQDAVKG	ANXA9	316	O76027
RDSGKQKAAYGDLSS	RNF113A	71	O15541
DGGSNVKARSSYNEK	BPNT2	221	Q9NX62
TSTGGANQADEKYFK	PEG3	1551	Q9GZU2
SKFRGHQKSKGNSYD	GID4	126	Q8IVV7
SQSDFKAFAGNSKSK	EXOSC10	821	Q01780
KSDTNGKYKNFATSN	APOB	1571	P04114
SSEDKKSKNGAYGRE	ATRX	1076	P46100
GQYSGNSFKKGDSNS	CDC7	506	O00311
KDSLGDSGYASQHKK	FOXN3	406	O00409
KFADDQGYGGSKLSS	DNAH7	3446	Q8WXX0
SEAKKLAGASINYGS	CEP350	841	Q5VT06
GESGDYKATQKIAFS	C1QB	111	P02746
IKKAGSGNYSGDISD	CYP11A1	186	P05108
KLHSNSDKGDGSVKY	CDH18	76	Q13634
ASGSFKLNKKAASGE	H1-4	101	P10412
AKQYAGTGALKTDFT	SACM1L	446	Q9NTJ5
AGQKGKTSVQKSSYE	OTOF	461	Q9HC10
GTGKKSTNSRFENYG	HNRNPUL1	306	Q9BUJ2
EKSLGLSKGNKYSAQ	EEF1E1	11	O43324
IGSKYSEQSKETNGS	RTN3	706	O95197
AGASQAKAYKSLGEG	SH3D19	171	Q5HYK7
TVKGGQNSTAASTKY	SYNRG	731	Q9UMZ2
GYRNKVNFSGSSKSD	TDRD9	646	Q8NDG6
ACKSVNGSHKYKGNS	NEO1	1141	Q92859
GKDGKKYSSLNLFDT	PRRC2A	11	P48634
DKGTLGSGSKNNIFY	POLR3A	651	O14802
ENKYSDSTGHSKAKN	WAC	66	Q9BTA9
AKIQGSKQFSYDGTD	PHLDB2	86	Q86SQ0
KGNKKNSTTNYRGTA	UHRF1BP1L	1141	A0JNW5
AQDLSNKSSYGLKGA	UBAP2	236	Q5T6F2
GSGKKKLSEQASNTY	PLCB1	476	Q9NQ66
KGLSSIKSYKANLNG	WDR76	286	Q9H967
KDSHYQKSSSKLDGN	TOPORS	821	Q9NS56
QKSSSKLDGNYKNES	TOPORS	826	Q9NS56
IDKGSAYGNSDSKQK	AGPAT4	361	Q9NRZ5
ASAANGNDSKKFKGD	PTBP1	36	P26599
SAGDAYASNKASKAA	PKP2	826	Q99959
QEYEDSGGSKTFSAK	TYW1B	616	Q6NUM6
GKKLLNSNKSGAAFS	ZNF181	206	Q2M3W8
YSDDASVGKGFSRKS	ZNF804A	236	Q7Z570
ANDYKDTLGKGSSLS	KRT71	501	Q3SY84