Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	cochlear hair cell ribbon synapse	CACNA1D CDH23 BSN	6.57e-06	6	146	3	GO:0098683
GeneOntologyCellularComponent	extrinsic component of membrane	CDH23 NOD2 JAK3 KIAA1755 CTBP1 BSN CDH15 PCSK9	2.18e-04	230	146	8	GO:0019898
GeneOntologyCellularComponent	extrinsic component of plasma membrane	CDH23 NOD2 JAK3 CTBP1 CDH15 PCSK9	4.06e-04	137	146	6	GO:0019897
Domain	GREB1	GREB1L GREB1	5.66e-05	2	141	2	PF15782
Domain	GREB1	GREB1L GREB1	5.66e-05	2	141	2	IPR028422
Domain	AUTS2	FBRS FBRSL1	1.69e-04	3	141	2	IPR023246
Domain	CAC1F_C	CACNA1C CACNA1D	1.69e-04	3	141	2	IPR031688
Domain	CAC1F_C	CACNA1C CACNA1D	1.69e-04	3	141	2	PF16885
Domain	RUN	SGSM1 RUSC2 RUBCN	3.16e-04	18	141	3	SM00593
Domain	VDCC_L_a1su	CACNA1C CACNA1D	3.36e-04	4	141	2	IPR005446
Domain	RUN	SGSM1 RUSC2 RUBCN	3.74e-04	19	141	3	PS50826
Domain	RUN	SGSM1 RUSC2 RUBCN	3.74e-04	19	141	3	PF02759
Domain	Run_dom	SGSM1 RUSC2 RUBCN	3.74e-04	19	141	3	IPR004012
Domain	EGF_CA	COMP VWCE JAG2 FBLN2 FBN3	4.87e-04	86	141	5	PF07645
Domain	EGF_Ca-bd_CS	COMP VWCE JAG2 FBLN2 FBN3	8.44e-04	97	141	5	IPR018097
Domain	EGF_CA	COMP VWCE JAG2 FBLN2 FBN3	9.25e-04	99	141	5	PS01187
Domain	HECT	TRIP12 AREL1 HECTD1	1.08e-03	27	141	3	PF00632
Domain	HECTc	TRIP12 AREL1 HECTD1	1.08e-03	27	141	3	SM00119
Domain	HECT_dom	TRIP12 AREL1 HECTD1	1.08e-03	27	141	3	IPR000569
Domain	HECT	TRIP12 AREL1 HECTD1	1.08e-03	27	141	3	PS50237
Domain	Ca_chan_IQ	CACNA1C CACNA1D	1.16e-03	7	141	2	SM01062
Domain	Ca_chan_IQ	CACNA1C CACNA1D	1.16e-03	7	141	2	PF08763
Domain	VDCC_a1su_IQ	CACNA1C CACNA1D	1.16e-03	7	141	2	IPR014873
Domain	GPHH	CACNA1C CACNA1D	1.16e-03	7	141	2	PF16905
Domain	GPHH_dom	CACNA1C CACNA1D	1.16e-03	7	141	2	IPR031649
Domain	TGFb_propeptide	GDF10 BMP6 BMP7	1.20e-03	28	141	3	PF00688
Domain	TGF-b_N	GDF10 BMP6 BMP7	1.20e-03	28	141	3	IPR001111
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA6C CRYBG2 B4GALNT4 MAN2A2 SZT2 CTC1 FBRS FBRSL1 AKNA GRID1 HDAC7 PLEKHH3 TRAK1 NOD2 MICALL1 JAG2 JAK3 KMT2D IL17RE NBEAL2 CCDC3 PDCD11 HECTD1 PRRT4 WNK2 CYB5R2	3.48e-12	1105	154	26	35748872
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SNX3 RANBP3 CARMIL1 PLEKHG2 MAP3K6 TRIP12 FAM53C HDAC7 TRAK1 RUSC2 MICALL1 CASKIN2 TRIM9 SAMD11 CEP112 HELZ HECTD1	3.08e-07	861	154	17	36931259
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SEMA6C SZT2 FBRSL1 AKNA SYNPO MICALL1 CASKIN2 TRIM9 NBEAL2 PDCD11 BSN WNK2 ZNF646	7.50e-07	529	154	13	14621295
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	REM1 CTC1 POLM UPK3B ARHGAP9 GRID1 PABPN1L MAP3K6 DLGAP3 CFAP126 FAM120C NBEAL2 KLHL33 MNT ZNF646	4.79e-06	832	154	15	36724073
Pubmed	NOD2 deficiency protects mice from the development of adoptive transfer colitis through the induction of regulatory T cells expressing forkhead box P3.	NOD2 FOXP3	1.95e-05	2	154	2	34186435
Pubmed	L-type calcium channel alpha-subunit and protein kinase inhibitors modulate Rem-mediated regulation of current.	CACNA1C REM1	1.95e-05	2	154	2	16648185
Pubmed	Different roles attributed to Cav1 channel subtypes in spontaneous action potential firing and fine tuning of exocytosis in mouse chromaffin cells.	CACNA1C CACNA1D	1.95e-05	2	154	2	21054386
Pubmed	Bone morphogenetic proteins inhibit CD40L/IL-21-induced Ig production in human B cells: differential effects of BMP-6 and BMP-7.	BMP6 BMP7	1.95e-05	2	154	2	21898381
Pubmed	An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.	CACNA1C CACNA1D	1.95e-05	2	154	2	24086669
Pubmed	The pattern recognition receptor NOD2 mediates Staphylococcus aureus-induced IL-17C expression in keratinocytes.	IL17C NOD2	1.95e-05	2	154	2	23892590
Pubmed	Differential zinc permeation and blockade of L-type Ca2+ channel isoforms Cav1.2 and Cav1.3.	CACNA1C CACNA1D	1.95e-05	2	154	2	26049024
Pubmed	Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers.	CACNA1C CACNA1D	1.95e-05	2	154	2	19225208
Pubmed	Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB.	CACNA1C CACNA1D	1.95e-05	2	154	2	16706838
Pubmed	Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations.	GREB1L GREB1	1.95e-05	2	154	2	29100090
Pubmed	Cutting edge: regulation of intestinal inflammation and barrier function by IL-17C.	IL17C IL17RE	1.95e-05	2	154	2	23024280
Pubmed	Temperature-sensitive Cav1.2 calcium channels support intrinsic firing of pyramidal neurons and provide a target for the treatment of febrile seizures.	CACNA1C CACNA1D	1.95e-05	2	154	2	23761887
Pubmed	Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits.	CACNA1C CACNA1D	1.95e-05	2	154	2	14981074
Pubmed	CaV1.2 and CaV1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum.	CACNA1C CACNA1D	1.95e-05	2	154	2	25292336
Pubmed	Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle.	CACNA1C CACNA1D	1.95e-05	2	154	2	17526649
Pubmed	Ligand-activated signal transduction in the 2-cell embryo.	CACNA1C CACNA1D	1.95e-05	2	154	2	12606379
Pubmed	Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.	CACNA1C CACNA1D	1.95e-05	2	154	2	24941892
Pubmed	Equal sensitivity of Cav1.2 and Cav1.3 channels to the opposing modulations of PKA and PKG in mouse chromaffin cells.	CACNA1C CACNA1D	1.95e-05	2	154	2	22826131
Pubmed	Transcriptional regulation of L-type calcium channel subtypes Cav1.2 and Cav1.3 by nicotine and their potential role in nicotine sensitization.	CACNA1C CACNA1D	1.95e-05	2	154	2	24470632
Pubmed	The aberrant promoter methylation of BMP3b and BMP6 in malignant pleural mesotheliomas.	GDF10 BMP6	1.95e-05	2	154	2	18949431
Pubmed	Cav1.2 and Cav1.3 L-type calcium channels operate in a similar voltage range but show different coupling to Ca(2+)-dependent conductances in hippocampal neurons.	CACNA1C CACNA1D	1.95e-05	2	154	2	24760982
Pubmed	HECTD1-Mediated Ubiquitination and Degradation of Rubicon Regulates Autophagy and Osteoarthritis Pathogenesis.	HECTD1 RUBCN	1.95e-05	2	154	2	36121967
Pubmed	A Gene Implicated in Activation of Retinoic Acid Receptor Targets Is a Novel Renal Agenesis Gene in Humans.	GREB1L GREB1	1.95e-05	2	154	2	28739660
Pubmed	Deletion of the L-type calcium channel Ca(V) 1.3 but not Ca(V) 1.2 results in a diminished sAHP in mouse CA1 pyramidal neurons.	CACNA1C CACNA1D	1.95e-05	2	154	2	20014384
Pubmed	Role of putative voltage-sensor countercharge D4 in regulating gating properties of CaV1.2 and CaV1.3 calcium channels.	CACNA1C CACNA1D	1.95e-05	2	154	2	30001160
Pubmed	Nod2 activates NF-kB in CD4+ T cells but its expression is dispensable for T cell-induced colitis.	NOD2 FOXP3	1.95e-05	2	154	2	24324812
Pubmed	Rescue and worsening of congenital heart block-associated electrocardiographic abnormalities in two transgenic mice.	CACNA1C CACNA1D	1.95e-05	2	154	2	21352396
Pubmed	Disruption of the presynaptic cytomatrix protein bassoon degrades ribbon anchorage, multiquantal release, and sound encoding at the hair cell afferent synapse.	CACNA1D BSN	1.95e-05	2	154	2	23467361
Pubmed	Molecular nature of anomalous L-type calcium channels in mouse cerebellar granule cells.	CACNA1C CACNA1D	1.95e-05	2	154	2	17409250
Pubmed	Neuronal L-type calcium channels open quickly and are inhibited slowly.	CACNA1C CACNA1D	1.95e-05	2	154	2	16267232
Pubmed	Developmental refinement of hair cell synapses tightens the coupling of Ca2+ influx to exocytosis.	CACNA1D BSN	1.95e-05	2	154	2	24442635
Pubmed	The role of L-type voltage-gated calcium channels Cav1.2 and Cav1.3 in normal and pathological brain function.	CACNA1C CACNA1D	1.95e-05	2	154	2	24996399
Pubmed	HIF2A and IGF2 expression correlates in human neuroblastoma cells and normal immature sympathetic neuroblasts.	IGF2 EPAS1	1.95e-05	2	154	2	23479510
Pubmed	MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping.	KMT2D FOXP3	1.95e-05	2	154	2	28759003
Pubmed	Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons.	CACNA1C CACNA1D	1.95e-05	2	154	2	24849370
Pubmed	Murine osteogenic protein (OP-1): high levels of mRNA in kidney.	BMP6 BMP7	1.95e-05	2	154	2	1715687
Pubmed	Divide and conquer: an L-type voltage-gated calcium channel subtype finds a role in conditioned fear.	CACNA1C CACNA1D	1.95e-05	2	154	2	17015854
Pubmed	Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area.	CACNA1C CACNA1D	1.95e-05	2	154	2	24848473
Pubmed	IL-17C/IL-17RE: Emergence of a Unique Axis in TH17 Biology.	IL17C IL17RE	1.95e-05	2	154	2	32174926
Pubmed	Interaction between gonadotropin-releasing hormone and bone morphogenetic protein-6 and -7 signaling in LβT2 gonadotrope cells.	BMP6 BMP7	1.95e-05	2	154	2	21846488
Pubmed	Interleukin 17 Receptor E (IL-17RE) and IL-17C Mediate the Recruitment of Neutrophils during Acute Streptococcus pneumoniae Pneumonia.	IL17C IL17RE	1.95e-05	2	154	2	31481409
Pubmed	Cardiac deletion of Smyd2 is dispensable for mouse heart development.	SMYD5 MRPS18A HELZ	2.36e-05	13	154	3	20305823
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	ATN1 RBM33 FBRS SMYD5 TEAD1 PCF11 KMT2D SCO1 PDCD11 HELZ	3.97e-05	457	154	10	32344865
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	CACNA1C ATN1 SYNPO VWCE RUSC2 JAG2 DLGAP3 FBLN2 TRIM9 PAFAH1B3 CTBP1	4.33e-05	560	154	11	21653829
Pubmed	Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.	COL15A1 COMP GDF10 NEDD9 BMP6 BMP7 PCSK9	4.44e-05	210	154	7	16537572
Pubmed	SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity.	TEAD1 SKP2 EIF3F	4.57e-05	16	154	3	29891922
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	COL15A1 COMP ABI3BP GDF10 FBLN2 PODN	4.98e-05	146	154	6	27068509
Pubmed	BMP4 substitutes for loss of BMP7 during kidney development.	BMP6 BMP7	5.83e-05	3	154	2	16154126
Pubmed	Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).	CACNA1C CACNA1D	5.83e-05	3	154	2	17767505
Pubmed	Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene.	FBLN2 ELN	5.83e-05	3	154	2	12618961
Pubmed	A mechanism underlying NOTCH-induced and ubiquitin-mediated JAK3 degradation.	SKP2 JAK3	5.83e-05	3	154	2	21969365
Pubmed	Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.	CACNA1C CACNA1D	5.83e-05	3	154	2	2173707
Pubmed	Excreted-secreted antigens of Toxoplasma gondii inhibit Foxp3 via IL-2Rγ/JAK3/Stats pathway.	JAK3 FOXP3	5.83e-05	3	154	2	30129110
Pubmed	A bone morphogenetic protein subfamily: chromosomal localization of human genes for BMP5, BMP6, and BMP7.	BMP6 BMP7	5.83e-05	3	154	2	1427904
Pubmed	Bone morphogenetic protein-2, -6, and -7 differently regulate osteogenic differentiation of human periodontal ligament stem cells.	BMP6 BMP7	5.83e-05	3	154	2	23853066
Pubmed	FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2.	SKP2 FOXP3	5.83e-05	3	154	2	18008005
Pubmed	G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.	CACNA1C CACNA1D	5.83e-05	3	154	2	26831068
Pubmed	Specific activation of PLEKHG2-induced serum response element-dependent gene transcription by four-and-a-half LIM domains (FHL) 1, but not FHL2 or FHL3.	PLEKHG2 FHL1	5.83e-05	3	154	2	28489964
Pubmed	Truncation of murine CaV1.2 at Asp 1904 increases CaV1.3 expression in embryonic atrial cardiomyocytes.	CACNA1C CACNA1D	5.83e-05	3	154	2	23338940
Pubmed	Immunohistochemical analysis revealed the expression of bone morphogenetic proteins-4, 6, 7, and 9 in human induced membrane samples treated with the Masquelet technique.	BMP6 BMP7	5.83e-05	3	154	2	35033126
Pubmed	Inhibition of the JAK/STAT Signaling Pathway in Regulatory T Cells Reveals a Very Dynamic Regulation of Foxp3 Expression.	JAK3 FOXP3	5.83e-05	3	154	2	27077371
Pubmed	CTC1 OB-B interaction with TPP1 terminates telomerase and prevents telomere overextension.	CTC1 TPP1	5.83e-05	3	154	2	37021555
Pubmed	The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts.	CACNA1C CACNA1D	5.83e-05	3	154	2	19351867
Pubmed	Bone morphogenetic proteins are overexpressed in the bone marrow of primary myelofibrosis and are apparently induced by fibrogenic cytokines.	BMP6 BMP7	5.83e-05	3	154	2	18349123
Pubmed	Truncation of murine CaV1.2 at Asp-1904 results in heart failure after birth.	CACNA1C CACNA1D	5.83e-05	3	154	2	21832054
Pubmed	IL-17C/IL-17 Receptor E Signaling in CD4+ T Cells Promotes TH17 Cell-Driven Glomerular Inflammation.	IL17C IL17RE	5.83e-05	3	154	2	29483158
Pubmed	Angiotensin II suppresses long-term depression in the lateral amygdala of mice via L-type calcium channels.	CACNA1C CACNA1D	5.83e-05	3	154	2	17289261
Pubmed	Potent inhibition of L-type Ca2+ currents by a Rad variant associated with congestive heart failure.	CACNA1C CACNA1D	5.83e-05	3	154	2	23973784
Pubmed	Four-and-a-half LIM Domains 1 (FHL1) Protein Interacts with the Rho Guanine Nucleotide Exchange Factor PLEKHG2/FLJ00018 and Regulates Cell Morphogenesis.	PLEKHG2 FHL1	5.83e-05	3	154	2	27765816
Pubmed	Single nucleotide polymorphisms associated with non-contact soft tissue injuries in elite professional soccer players: influence on degree of injury and recovery time.	IGF2 ELN	5.83e-05	3	154	2	23890452
Pubmed	MicroRNA-1976 regulates degeneration of the sinoatrial node by targeting Cav1.2 and Cav1.3 ion channels.	CACNA1C CACNA1D	5.83e-05	3	154	2	31302118
Pubmed	Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone.	BMP6 BMP7	5.83e-05	3	154	2	2263636
Pubmed	Distinct localization and modulation of Cav1.2 and Cav1.3 L-type Ca2+ channels in mouse sinoatrial node.	CACNA1C CACNA1D	5.83e-05	3	154	2	23045342
Pubmed	Cav1.3 channels control D2-autoreceptor responses via NCS-1 in substantia nigra dopamine neurons.	CACNA1C CACNA1D	5.83e-05	3	154	2	24934288
Pubmed	Bone morphogenetic proteins 4, 6, and 7 are up-regulated in mouse spinal cord during experimental autoimmune encephalomyelitis.	BMP6 BMP7	5.83e-05	3	154	2	17722066
Pubmed	IGF2-derived miR-483-3p associated with Hirschsprung's disease by targeting FHL1.	IGF2 FHL1	5.83e-05	3	154	2	30073757
Pubmed	Growth differentiation factor 3 is induced by bone morphogenetic protein 6 (BMP-6) and BMP-7 and increases luteinizing hormone receptor messenger RNA expression in human granulosa cells.	BMP6 BMP7	5.83e-05	3	154	2	22305102
Pubmed	Synergistic effects of BMP-2, BMP-6 or BMP-7 with human plasma fibronectin onto hydroxyapatite coatings: A comparative study.	BMP6 BMP7	5.83e-05	3	154	2	28434979
Pubmed	Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells.	CDH23 CDH15	5.83e-05	3	154	2	17805295
Pubmed	TLR2- and nucleotide-binding oligomerization domain 2-dependent Krüppel-like factor 2 expression downregulates NF-kappa B-related gene expression.	KLF2 NOD2	5.83e-05	3	154	2	20525885
Pubmed	Human transcription factor protein interaction networks.	ATXN7L2 ATN1 RBM33 FBRS FBRSL1 TEAD1 MRPS18A PCF11 KMT2D TRIM9 SAMD11 TLE4 PDCD11 HELZ CTBP1 EIF3F FHL1 MNT	6.65e-05	1429	154	18	35140242
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	ATN1 FBRS FBRSL1 SKP2 TRIP12 FAM53C TRAK1 KMT2D CTBP1 MNT	7.70e-05	495	154	10	27705803
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CACNA1C NSUN5P1 MIA3 SGSM1 CARMIL1 FBRSL1 SYNPO ZNF385B JAG2 IGF2 PTPRN2 FAM120C CTBP1 GREB1 HECTD1 PCDH1 WNK2 CDH15	1.12e-04	1489	154	18	28611215
Pubmed	Immunohistochemical localization of bone morphogenetic proteins (BMPs) 2, 4, 6, and 7 during induced heterotopic bone formation.	BMP6 BMP7	1.16e-04	4	154	2	17262821
Pubmed	Forelimb contractures and abnormal tendon collagen fibrillogenesis in fibulin-4 null mice.	FBLN2 ELN	1.16e-04	4	154	2	26711913
Pubmed	Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.	CACNA1C CACNA1D	1.16e-04	4	154	2	20937870
Pubmed	Genome-wide methylation study on depression: differential methylation and variable methylation in monozygotic twins.	CACNA1C IGF2	1.16e-04	4	154	2	25918994
Pubmed	Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages.	HDAC7 CTBP1	1.16e-04	4	154	2	23853092
Pubmed	Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation.	KLF2 FOXP3	1.16e-04	4	154	2	37889750
Pubmed	FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression.	HDAC7 FOXP3	1.16e-04	4	154	2	17360565
Pubmed	The oxygen sensor prolyl hydroxylase domain 2 regulates the in vivo suppressive capacity of regulatory T cells.	EPAS1 FOXP3	1.16e-04	4	154	2	35192456
Pubmed	The human gene CXorf17 encodes a member of a novel family of putative transmembrane proteins: cDNA cloning and characterization of CXorf17 and its mouse ortholog orf34.	FAM120AOS FAM120C	1.16e-04	4	154	2	14585507
Pubmed	Antagonistic effects of bone morphogenetic protein-4 and -7 on renal mesangial cell proliferation induced by aldosterone through MAPK activation.	BMP6 BMP7	1.16e-04	4	154	2	17244894
Pubmed	Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via alpha-actinin2.	CACNA1C CACNA1D	1.16e-04	4	154	2	17110593
Pubmed	Signaling through IL-17C/IL-17RE is dispensable for immunity to systemic, oral and cutaneous candidiasis.	IL17C IL17RE	1.16e-04	4	154	2	25849644
Pubmed	Nfkbid Overexpression in Nonobese Diabetic Mice Elicits Complete Type 1 Diabetes Resistance in Part Associated with Enhanced Thymic Deletion of Pathogenic CD8 T Cells and Increased Numbers and Activity of Regulatory T Cells.	NFKBID FOXP3	1.16e-04	4	154	2	35760520
Interaction	TOP3B interactions	SEMA6C CRYBG2 B4GALNT4 MAN2A2 SZT2 CTC1 RBM33 FBRS FBRSL1 AKNA GRID1 HDAC7 PLEKHH3 TRAK1 NOD2 MICALL1 JAG2 JAK3 KMT2D FAM120C IL17RE NBEAL2 CCDC3 PDCD11 HELZ HECTD1 PRRT4 WNK2 CYB5R2	8.59e-07	1470	148	29	int:TOP3B
Coexpression	GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	SEMA6C NSUN5P1 NEU4 ATN1 SZT2 RBM33 POLM RANBP3 IL17C FBRSL1 HDAC7 MICALL1 KMT2D ZNF646	1.28e-08	338	153	14	M17094
Coexpression	AIZARANI_LIVER_C10_MVECS_1	COL15A1 ATN1 SYNPO HDAC7 KLF2 NEDD9 SHROOM4 FBLN2 CASKIN2 TNS1 EPAS1	5.59e-07	269	153	11	M39114
CoexpressionAtlas	geo_heart_top-relative-expression-ranked_2500_k-means-cluster#5	SEMA6C CACNA1C SGSM1 COL15A1 CDH23 SYNPO ZNF385B GDF10 TRAK1 AJM1 KIAA1755 ELN FHL1 WNK2 SSBP3-AS1	1.80e-05	586	150	15	geo_heart_2500_K5
CoexpressionAtlas	ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3	COL15A1 RTL5 LINC00472 GRID1 GDF10 RUSC2 GREB1L NEDD9 BMP7 FBLN2 IGF2 CFAP126 PTPRN2 SAMD11 BARHL1 CCDC3 SORCS2 MKX ELN ARRDC3 PRRT4	2.93e-05	1094	150	21	ratio_EB_vs_SC_2500_K3
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP SYNPO HSPA12B KLF2 JAG2 SHROOM4 FBLN2 CASKIN2 CCDC3 ELN EPAS1	1.21e-10	198	156	11	5e781583908c4ee107d986904a646a7c6b8e3591
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GIMAP4 ABI3BP SYNPO HSPA12B KLF2 JAG2 FBLN2 CCDC3 ELN EPAS1	1.54e-09	191	156	10	b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABI3BP SYNPO HSPA12B JAG2 NEDD9 SHROOM4 FBLN2 IGF2 ELN EPAS1	1.54e-09	191	156	10	adb2e3efcad02889d8229325080da5e7830fd3ae
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP SYNPO HSPA12B KLF2 JAG2 BMP6 FBLN2 CCDC3 ELN EPAS1	1.70e-09	193	156	10	0b328f725f6feba263783eaca60c142e80df90f3
ToppCell	cellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GIMAP4 ABI3BP SYNPO HSPA12B KLF2 JAG2 FBLN2 IGF2 ELN EPAS1	1.88e-09	195	156	10	75db19c0371320ea5fce1d6de8c1b40b1e6a2e58
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GIMAP4 ABI3BP SYNPO JAG2 SHROOM4 FBLN2 IGF2 CCDC3 ELN EPAS1	2.07e-09	197	156	10	61b1b10a017cbeb17f8529fcae66cba77ee2f115
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GIMAP4 ABI3BP SYNPO HSPA12B KLF2 JAG2 FBLN2 CCDC3 ELN EPAS1	2.40e-09	200	156	10	93e13937ec74418a697c37d56f57509fb2154780
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SEMA6C COMP SYNPO ZNF385B EXTL1 GFRA4 GDF10 IGF2 KIAA1755	8.93e-09	169	156	9	58e22f9119240664515fe91ca53812611a8f17d6
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA6C COMP ABI3BP FBLN2 IGF2 SAMD11 PODN ELN FHL1	1.78e-08	183	156	9	2beb5414958d38a5341870d55229f3b1707e76bf
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP SYNPO HSPA12B KLF2 JAG2 FBLN2 CASKIN2 CCDC3 ELN	2.25e-08	188	156	9	a37edd8f9e4a4e336b5acbb0407d3d275975cee8
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COMP ABI3BP FBLN2 IGF2 KIAA1755 PODN ELN GREB1 FHL1	2.25e-08	188	156	9	e18065bbc26d6f3774fd1f478fb41d8fb555fa26
ToppCell	Endothelial-A-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	COL15A1 SHROOM4 FBLN2 IGF2 CASKIN2 CCDC3 ELN PCDH1 EPAS1	2.25e-08	188	156	9	0824d567356d360fd8e78e840c30529c139f98a1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP SYNPO HSPA12B KLF2 JAG2 FBLN2 CCDC3 ELN EPAS1	2.36e-08	189	156	9	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP HSPA12B KLF2 JAG2 BMP6 FBLN2 CCDC3 ELN EPAS1	2.47e-08	190	156	9	bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL15A1 COMP ABI3BP GDF10 FBLN2 KIAA1755 PODN ELN FHL1	2.70e-08	192	156	9	b9e4585bea280ca0ae159f0c6a2bf7b88a15a6e6
ToppCell	IPF-Endothelial-VE_Arterial\|IPF / Disease state, Lineage and Cell class	SYNPO TEAD1 HSPA12B JAG2 SHROOM4 BMP6 IGF2 PCDH1 EPAS1	2.83e-08	193	156	9	bf83b1fe9d38408f30eee4eb634341c04ef82791
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP SYNPO HSPA12B KLF2 JAG2 FBLN2 CCDC3 ELN EPAS1	2.95e-08	194	156	9	b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYNPO HSPA12B JAG2 SHROOM4 FBLN2 IGF2 CCDC3 ELN EPAS1	3.09e-08	195	156	9	b0979c1b5e4576468b8fe4e9027650859e598b34
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABI3BP HSPA12B KLF2 JAG2 NEDD9 FBLN2 IGF2 CCDC3 EPAS1	3.23e-08	196	156	9	cf7f384c1771274e766bab03ecc3dfbd13f2df60
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C CACNA1D COL15A1 COMP ABI3BP FBLN2 KIAA1755 PODN ELN	3.37e-08	197	156	9	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GIMAP4 SYNPO JAG2 SHROOM4 FBLN2 IGF2 CCDC3 ELN EPAS1	3.52e-08	198	156	9	58508a8df2714d769f137794c29441a7bd38b350
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP SYNPO HSPA12B KLF2 JAG2 FBLN2 CCDC3 ELN EPAS1	3.68e-08	199	156	9	a3ec743b978ba8fdf1677b4971b5731f50ddd30f
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-3\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	CACNA1C COMP ABI3BP HSPA12B GDF10 FBLN2 PODN ELN FHL1	3.68e-08	199	156	9	07b8c33342c62afd9c63ec2d757cfa3ba65d2a98
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP SYNPO HSPA12B KLF2 JAG2 FBLN2 CCDC3 ELN EPAS1	3.68e-08	199	156	9	9b02acae6325b0ac9642438a4431285ff396e5fe
ToppCell	distal-2-mesenchymal-Adventitial_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL15A1 COMP ABI3BP GDF10 FBLN2 SAMD11 KIAA1755 PODN GREB1	3.68e-08	199	156	9	97b475f9110ef7bb29d9cf2109b7e43177830f05
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ABI3BP SYNPO JAG2 BMP6 FBLN2 CCDC3 ELN PCDH1 EPAS1	3.68e-08	199	156	9	6a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP SYNPO HSPA12B KLF2 JAG2 FBLN2 CCDC3 ELN EPAS1	3.68e-08	199	156	9	33f1669eeb701986b4dec409efdb6c06c3c41c2b
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL15A1 COMP ABI3BP GDF10 FBLN2 SAMD11 PODN ELN FHL1	3.68e-08	199	156	9	fb580e9321ddf97c73b2e356cd82523db74a38a2
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CACNA1C TEAD1 PLEKHH3 SHROOM4 BMP6 CEP112 KIAA1755 TNS1 EPAS1	3.84e-08	200	156	9	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GIMAP4 SYNPO HSPA12B JAG2 SHROOM4 BMP6 FBLN2 IGF2 CCDC3	3.84e-08	200	156	9	5ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CACNA1C TEAD1 PLEKHH3 SHROOM4 BMP6 CEP112 KIAA1755 TNS1 EPAS1	3.84e-08	200	156	9	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CACNA1C TEAD1 PLEKHH3 SHROOM4 BMP6 CEP112 KIAA1755 TNS1 EPAS1	3.84e-08	200	156	9	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	distal-1-Endothelial-Bronchial_Vessel_2\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GIMAP4 NEDD9 SHROOM4 BMP6 FBLN2 CASKIN2 CCDC3 PCDH1 EPAS1	3.84e-08	200	156	9	aa8f8a0271c1363981e6ca1b2c1f0a8eb2652602
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CACNA1C TEAD1 PLEKHH3 SHROOM4 BMP6 CEP112 KIAA1755 TNS1 EPAS1	3.84e-08	200	156	9	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CACNA1C TEAD1 PLEKHH3 SHROOM4 BMP6 CEP112 KIAA1755 TNS1 EPAS1	3.84e-08	200	156	9	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	Hematolymphoid-Endothelial\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CACNA1C TEAD1 PLEKHH3 SHROOM4 BMP6 CEP112 KIAA1755 TNS1 EPAS1	3.84e-08	200	156	9	7136936d05ab344a560cf159684c881063b5430d
ToppCell	Biopsy_IPF-Mesenchymal-Myofibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	COL15A1 COMP ABI3BP GDF10 FBLN2 SAMD11 PODN ELN FHL1	3.84e-08	200	156	9	c2c6f687c49ba790174b27c7b8b084af30b34c86
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NEU4 COL15A1 HSPA12B MAP3K6 KLF2 JAG2 CFAP126 EPAS1	1.10e-07	162	156	8	c399b9e4854916a59f5cae2d8dbf19660f8759be
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NEU4 COL15A1 HSPA12B MAP3K6 KLF2 JAG2 CFAP126 EPAS1	1.10e-07	162	156	8	a291248b693c771845174393934a782f1d8bd7ce
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA6C SYNPO HSPA12B KLF2 JAG2 CCDC3 KDM8 ELN	1.32e-07	166	156	8	ec719368295133da2f7ff587c5329ed6db1dd56d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP HSPA12B KLF2 JAG2 FBLN2 CCDC3 ELN EPAS1	1.32e-07	166	156	8	8e5f2afbeffae5e77fcb29e8fe9f5aa49779b619
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO HSPA12B KLF2 JAG2 FBLN2 CCDC3 ELN EPAS1	2.26e-07	178	156	8	5f779a66aa42d1d8e8af17b4a08d5dcc733efd4c
ToppCell	Endothelial-A-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	SEMA6C ABI3BP SHROOM4 BMP6 IGF2 CCDC3 ELN EPAS1	2.26e-07	178	156	8	2f2602b9305d55f25afa9861dd6c6347ae179337
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D122\|Adult / Lineage, Cell type, age group and donor	COL15A1 ABI3BP FBLN2 SAMD11 PODN ELN GREB1 KLHL33	2.91e-07	184	156	8	2b7e6f91e11c228f0521e099886867d9e998e78d
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABI3BP HSPA12B BATF2 FBLN2 IGF2 CASKIN2 ARRDC3 EPAS1	2.91e-07	184	156	8	16ed515fb673a9d6973133afcda0a3fba4a8d9dc
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	ABI3BP ZNF385B HSPA12B BMP7 FBLN2 IGF2 PODN ELN	3.03e-07	185	156	8	506eee2c1b6e8acec3aa8b2c66868010006c4c14
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNPO HSPA12B MAP3K6 JAG2 FBLN2 IGF2 ELN PRRT4	3.03e-07	185	156	8	f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	CACNA1C CACNA1D ABI3BP FBLN2 KIAA1755 PODN ELN GREB1	3.03e-07	185	156	8	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNPO MAP3K6 JAG2 FBLN2 IGF2 ELN PRRT4 EPAS1	3.29e-07	187	156	8	ddfc2d1d9fcc3d8e4d3d015576bb17eebf44ada9
ToppCell	Endothelial-A-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	HSPA12B SHROOM4 BMP6 IGF2 CASKIN2 CCDC3 ELN PCDH1	3.29e-07	187	156	8	febe0b99a6a815ce687160a0e7af55228b1d5beb
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNPO HSPA12B MAP3K6 JAG2 FBLN2 IGF2 ELN PRRT4	3.29e-07	187	156	8	e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCell	PND07-28-samps-Endothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	GIMAP4 HSPA12B JAG2 FBLN2 CASKIN2 PODN PCDH1 EPAS1	3.57e-07	189	156	8	eb2f8c8a90e5e9f6697a2d13274c94f40e1973e4
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	GIMAP4 HSPA12B JAG2 FBLN2 CASKIN2 PODN PCDH1 EPAS1	3.57e-07	189	156	8	d4a25d59d88325d3b20f4287e9b1160c82961a96
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	ABI3BP SYNPO JAG2 BMP6 FBLN2 CCDC3 ELN EPAS1	3.71e-07	190	156	8	1519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CACNA1D ABI3BP GRID1 CCDC3 SORCS2 KIAA1755 FHL1	3.71e-07	190	156	8	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	3'-Child04-06-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GIMAP4 SYNPO HSPA12B JAG2 SHROOM4 FBLN2 CCDC3 EPAS1	3.71e-07	190	156	8	ec6b8e2852e1cce0217ff61243defe98b2351640
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GIMAP4 SYNPO HSPA12B JAG2 SHROOM4 FBLN2 IGF2 CCDC3	3.86e-07	191	156	8	04c7aa2e39fdd08ca24c10d43b29a5e41a73b9e0
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL15A1 COMP ABI3BP GDF10 FBLN2 KIAA1755 PODN ELN	3.86e-07	191	156	8	0fae1c2ef9f83ac7721d0a9d69455bf97eed9257
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GIMAP4 SYNPO HSPA12B JAG2 SHROOM4 FBLN2 IGF2 CCDC3	3.86e-07	191	156	8	db8dd6bbba803585bdd6a55d5c403d383f2e9acf
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REM1 COL15A1 ABI3BP GDF10 FBLN2 KIAA1755 PODN ELN	4.02e-07	192	156	8	8937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REM1 COL15A1 ABI3BP GDF10 FBLN2 KIAA1755 PODN ELN	4.02e-07	192	156	8	e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REM1 COL15A1 ABI3BP GDF10 FBLN2 KIAA1755 PODN ELN	4.02e-07	192	156	8	ac1477433704573f95111eee6263b93668d2845e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HSPA12B TRAK1 KLF2 JAG2 FBLN2 CASKIN2 CCDC3 EPAS1	4.02e-07	192	156	8	3259cb89d6bcf0a3c6ff1f64d85e8a1f54124e91
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COMP ABI3BP GDF10 FBLN2 SAMD11 PODN ELN FHL1	4.02e-07	192	156	8	c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Vein\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SEMA6C GIMAP4 HSPA12B MAP3K6 FBLN2 IGF2 SAMD11 ELN	4.02e-07	192	156	8	717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO HSPA12B KLF2 JAG2 FBLN2 CCDC3 ELN EPAS1	4.02e-07	192	156	8	56b021c297a21dff357531f21e2464f85186106d
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CACNA1D ABI3BP GRID1 GDF10 CCDC3 ELN FHL1	4.02e-07	192	156	8	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP HSPA12B KLF2 JAG2 FBLN2 CCDC3 ELN EPAS1	4.18e-07	193	156	8	2e72309607902dabe3218888b22a77fe941f3570
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP SYNPO HSPA12B JAG2 FBLN2 CCDC3 ELN EPAS1	4.18e-07	193	156	8	cc355b2ed6510619cad969ae074126d7c8db784d
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TEAD1 HSPA12B BMP7 IGF2 KIAA1755 PODN ELN FBN3	4.18e-07	193	156	8	3d85c28f6ebdcb15e875ad01d52d6c138fbf8525
ToppCell	18-Distal-Mesenchymal-Cartilage\|Distal / Age, Tissue, Lineage and Cell class	COL15A1 COMP EXTL1 GDF10 FBLN2 IGF2 KIAA1755 ELN	4.18e-07	193	156	8	52f3d1bb8d8ca91ba12439d46392f377928ff8f8
ToppCell	IPF-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	SYNPO TEAD1 JAG2 SHROOM4 BMP6 IGF2 PCDH1 EPAS1	4.18e-07	193	156	8	70a9aadda83a97e06e9bc2d1327ce60dd3c58767
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HSPA12B KLF2 JAG2 BMP6 FBLN2 CCDC3 ELN EPAS1	4.18e-07	193	156	8	6a623acd1adad9a78eddc32ffedb16352ad3fdfa
ToppCell	droplet-Heart-nan-3m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 ABI3BP CEP112 KIAA1755 PODN ELN ARRDC3 FHL1	4.35e-07	194	156	8	ce32e60bcea1b8baf496ce9050832bc8c77d8434
ToppCell	droplet-Heart-nan-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 ABI3BP CEP112 KIAA1755 PODN ELN ARRDC3 FHL1	4.35e-07	194	156	8	a1dc157148885cc8d3685ac81a1f4e3562aeecc9
ToppCell	EC-Arteriolar_ECs\|World / Lineage and Cell class	HSPA12B KLF2 JAG2 FBLN2 IGF2 ELN PCDH1 EPAS1	4.35e-07	194	156	8	38f0c52de252101d4bc8633af80002061635e487
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO HSPA12B KLF2 JAG2 FBLN2 CCDC3 ELN EPAS1	4.52e-07	195	156	8	6bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COMP ABI3BP GDF10 FBLN2 SAMD11 PODN ELN FHL1	4.52e-07	195	156	8	1236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SNX3 COL15A1 HSPA12B JAG2 SHROOM4 IGF2 CASKIN2 EPAS1	4.52e-07	195	156	8	a432d69b0172211ee4d53675936a1dc9ce1ae1f0
ToppCell	Bronchial_Biopsy-Mesenchymal-Fibroblasts\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	COL15A1 COMP ABI3BP GDF10 FBLN2 SAMD11 PODN FHL1	4.52e-07	195	156	8	5870b2956d50d6550a3174a220a6cc70c5538d70
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP HSPA12B KLF2 JAG2 FBLN2 CCDC3 ELN EPAS1	4.52e-07	195	156	8	77e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL15A1 COMP ABI3BP GDF10 FBLN2 SAMD11 PODN FHL1	4.70e-07	196	156	8	e7bfd4fb400ae0c473131d0fa306c26be08a6d03
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL15A1 COMP ABI3BP GDF10 FBLN2 SAMD11 PODN FHL1	4.70e-07	196	156	8	82fad623212d986a7fca3496faf3f8c8f5b83a11
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP SYNPO HSPA12B JAG2 FBLN2 CCDC3 ELN EPAS1	4.70e-07	196	156	8	a20a56d8997d6db2a10046c8801c619a379de83c
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL15A1 COMP ABI3BP GDF10 FBLN2 SAMD11 PODN FHL1	4.70e-07	196	156	8	85e5046f774537684e1443c0fc147d562b7068d0
ToppCell	metastatic_Lymph_Node-Fibroblasts\|metastatic_Lymph_Node / Location, Cell class and cell subclass	COL15A1 COMP ABI3BP FBLN2 CCDC3 KIAA1755 PODN ELN	4.70e-07	196	156	8	275e153347caf94edc0c50021bbab49c8696fecb
ToppCell	(4)_Blood_vessel\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	GIMAP4 COL15A1 HSPA12B KLF2 NEDD9 FBLN2 IGF2 EPAS1	4.88e-07	197	156	8	1b82979a41ef46c814c82527a585900586d71260
ToppCell	(4)_Endothelial_cells\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	GIMAP4 COL15A1 HSPA12B KLF2 NEDD9 FBLN2 IGF2 EPAS1	4.88e-07	197	156	8	dd9abb43c23e7698433e455eacbf5b23b0a756c2
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO HSPA12B KLF2 JAG2 FBLN2 CCDC3 ELN EPAS1	5.07e-07	198	156	8	b027a141ab531d0f5d6a26811a53427e7b0771dd
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GIMAP4 ABI3BP SYNPO KLF2 JAG2 FBLN2 ELN EPAS1	5.07e-07	198	156	8	8a55589b9244283e4b0b423a4a6d6202e8e0fec9
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C COMP ABI3BP GDF10 FBLN2 SAMD11 PODN ELN	5.07e-07	198	156	8	300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	CACNA1C CACNA1D ABI3BP FBLN2 PODN ELN GREB1 FHL1	5.07e-07	198	156	8	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	5'-Adult-Distal_Rectal-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GIMAP4 ABI3BP KLF2 JAG2 FBLN2 IGF2 ELN EPAS1	5.07e-07	198	156	8	8d6b0b9da7c1e64155cbcbb04ad38d129a29030c
ToppCell	3'-Broncho-tracheal-Mesenchymal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL15A1 COMP ABI3BP GDF10 FBLN2 CCDC3 PODN FHL1	5.07e-07	198	156	8	4961a3e9b953679648586afed04869ff36b81820
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	ABI3BP UPK3B SYNPO NEDD9 IL17RE NBEAL2 FHL1 FBN3	5.27e-07	199	156	8	5a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABI3BP SYNPO NEDD9 SHROOM4 IGF2 CASKIN2 PCDH1 EPAS1	5.27e-07	199	156	8	6e3a226ebba023e3e909d7a7188137da4f1fd7fc
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP SYNPO HSPA12B JAG2 FBLN2 CCDC3 ELN EPAS1	5.27e-07	199	156	8	f35e9c05d0a0339ff691b38564da7aad8e9218aa
ToppCell	3'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GIMAP4 ABI3BP SYNPO KLF2 FBLN2 IGF2 ELN EPAS1	5.27e-07	199	156	8	0075bcc7d2a5031e76a24cb176e16ac998d846fd
ToppCell	cellseq-Endothelial-Endothelial_Vascular-Endothelial_capillary\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GIMAP4 HSPA12B KLF2 NEDD9 SHROOM4 CASKIN2 PCDH1 EPAS1	5.27e-07	199	156	8	5f67ea58512856cbdcef759088a5869720a947a8
ToppCell	cellseq-Endothelial-Endothelial_Vascular\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GIMAP4 HSPA12B KLF2 NEDD9 SHROOM4 CASKIN2 PCDH1 EPAS1	5.27e-07	199	156	8	307d29816a224193aa3d8c4540e128b2ad2e90b9
Computational	Bone remodeling.	COMP EXTL1 JAK3 BMP7 IGF2	4.50e-05	54	79	5	MODULE_234
Drug	Meticrane [1084-65-7]; Up 200; 14.6uM; MCF7; HT_HG-U133A	CCDC28B RANBP3 HDAC7 TRAK1 RUSC2 GREB1L BMP6 TPP1 NBEAL2 KDM8	9.06e-07	198	152	10	1671_UP
Drug	Resveratrol [501-36-0]; Up 200; 17.6uM; PC3; HT_HG-U133A	REM1 ITGA2B RUSC2 GREB1L NEDD9 HROB PTPRN2 TNS1 PCDH1	7.02e-06	196	152	9	5084_UP
Drug	Methiazole; Down 200; 15uM; PC3; HT_HG-U133A	CRYBG2 REM1 ITGA2B HDAC7 GREB1L FAM120C TPP1 KDM8 CYB5R2	7.02e-06	196	152	9	3796_DN
Drug	pioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A	CCDC28B CTC1 FBRS ITGA2B TDRD1 RUSC2 BMP6 TPP1 FHL1	7.32e-06	197	152	9	5925_UP
Drug	Nitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A	CCDC28B POLM SYNPO ITGA2B RUSC2 FAM120C CCDC87 BSN TNS1	7.32e-06	197	152	9	6043_UP
Drug	Tribenoside [10310-32-4]; Up 200; 8.4uM; HL60; HT_HG-U133A	CTC1 RANBP3 FBRS MICALL1 BMP6 HROB TPP1 TNS1	3.40e-05	184	152	8	2946_UP
Drug	thioridazine hydrochloride; Up 200; 10uM; PC3; HT_HG-U133A	CRYBG2 ATN1 FBRS RUSC2 BMP6 TPP1 ELN CDH15	3.96e-05	188	152	8	5921_UP
Drug	0317956-0000 [391210-11-0]; Down 200; 10uM; PC3; HT_HG-U133A	ATN1 WDR18 HDAC7 RUSC2 MICALL1 HROB IGF2 CASKIN2	4.95e-05	194	152	8	4331_DN
Drug	6-Hydroxytropinone [5932-53-6]; Up 200; 25.8uM; MCF7; HT_HG-U133A	ATN1 POLM MAP3K6 HROB NBEAL2 PDCD11 HELZ PCDH1	5.32e-05	196	152	8	4833_UP
Drug	Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A	CACNA1D CRYBG2 CCDC28B HDAC7 BMP6 HROB CCDC87 FHL1	5.52e-05	197	152	8	3577_UP
Drug	(+,-)-Synephrine [94-07-5]; Up 200; 24uM; PC3; HT_HG-U133A	CTC1 HDAC7 TRAK1 RUSC2 BMP6 BMP7 PRICKLE3 KDM8	5.52e-05	197	152	8	7150_UP
Drug	Hydroxytacrine maleate (R,S) [118909-22-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A	SZT2 POLM TRAK1 JAG2 HROB CEP112 TNS1 ZNF646	5.52e-05	197	152	8	3292_UP
Drug	Catechin-(+,-) hydrate [7295-85-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A	ATN1 RANBP3 TRAK1 RUSC2 KDM8 FHL1 TNS1 PCDH1	5.52e-05	197	152	8	3351_UP
Drug	Ajmaline [4360-12-7]; Up 200; 12.2uM; HL60; HG-U133A	CRYBG2 REM1 ATN1 RANBP3 FBRS ITGA2B PAFAH1B3 ELN	5.52e-05	197	152	8	1749_UP
Drug	(+,-)-Synephrine [94-07-5]; Up 200; 24uM; MCF7; HT_HG-U133A	CRYBG2 MAN2A2 CCDC28B POLM TRAK1 RUSC2 BMP6 FHL1	5.52e-05	197	152	8	6798_UP
Drug	PNU-0230031 [267429-39-0]; Up 200; 1uM; MCF7; HT_HG-U133A	CACNA1D ABI3BP CCDC28B ITGA2B SKP2 RUSC2 TNS1 EPAS1	5.52e-05	197	152	8	3632_UP
Drug	2-Aminobenzenesulfonamide [3306-62-5]; Up 200; 23.2uM; MCF7; HT_HG-U133A	ABI3BP CCDC28B SKP2 HDAC7 NEDD9 NBEAL2 FHL1 PCDH1	5.72e-05	198	152	8	5422_UP
Drug	Atropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A	MIA3 ATN1 SKP2 RUSC2 GREB1L CEP112 CCDC87 PCDH1	5.72e-05	198	152	8	2216_UP
Drug	LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A	ATN1 RUSC2 NOD2 GREB1L HROB PRICKLE3 FHL1 PCDH1	5.72e-05	198	152	8	5213_UP
Drug	Benzamil hydrochloride [2898-76-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A	REM1 POLM TRAK1 NOD2 HROB PTPRN2 FAM120C ZNF646	5.72e-05	198	152	8	6056_UP
Drug	Isocarboxazid [59-63-2]; Up 200; 17.2uM; MCF7; HT_HG-U133A	ABI3BP CCDC28B SKP2 TRAK1 FAM120C CEP112 KDM8 FHL1	5.72e-05	198	152	8	3424_UP
Drug	rapamycin, Streptomyces hygroscepicus; Up 200; 0.1uM; MCF7; HT_HG-U133A	CTC1 FBRS ITGA2B RUSC2 NOD2 BMP6 TPP1 ZNF646	5.92e-05	199	152	8	5927_UP
Drug	Vancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; MCF7; HT_HG-U133A	CRYBG2 SYNPO CEP112 TPP1 ELN PCDH1 NPAS1 ZNF646	5.92e-05	199	152	8	4423_UP
Drug	Felbinac [5728-52-9]; Up 200; 18.8uM; MCF7; HT_HG-U133A	MAN2A2 SZT2 POLM RUSC2 HROB CCDC87 FHL1 ZNF646	6.14e-05	200	152	8	3398_UP
Disease	anthropometric measurement	MIA3 TEAD1 BMP7 HROB CCDC3 MKX BSN	1.95e-05	168	144	7	EFO_0004302
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1C CACNA1D	1.41e-04	4	144	2	DOID:0060173 (implicated_via_orthology)
Disease	diabetes mellitus (implicated_via_orthology)	BMP6 BMP7 PTPRN2	2.73e-04	26	144	3	DOID:9351 (implicated_via_orthology)
Disease	breast cancer (is_marker_for)	SKP2 BMP6 BMP7 KMT2D IGF2 KDM8	3.05e-04	185	144	6	DOID:1612 (is_marker_for)
Disease	urticaria, response to non-steroidal anti-inflammatory, angioedema	ABI3BP EPAS1	8.33e-04	9	144	2	EFO_0005531, EFO_0005532, EFO_0005533
Disease	Marfan syndrome (implicated_via_orthology)	BMP6 BMP7	1.04e-03	10	144	2	DOID:14323 (implicated_via_orthology)
Disease	Reactive hypoglycemia	CACNA1C IGF2	1.04e-03	10	144	2	C0271710
Disease	Fasting Hypoglycemia	CACNA1C IGF2	1.04e-03	10	144	2	C0271708
Disease	Hypoglycemia	CACNA1C IGF2	1.26e-03	11	144	2	C0020615
Disease	granulins measurement	CDH23 ITGA2B	1.51e-03	12	144	2	EFO_0008141
Disease	cognitive function measurement	CACNA1C CACNA1D SGSM1 ATXN7L2 SZT2 ARHGAP9 COPG2 GRID1 TEAD1 NEDD9 KMT2D PTPRN2 FHDC1 PCDH1 WNK2 NPAS1	1.75e-03	1434	144	16	EFO_0008354
Disease	platelet-to-lymphocyte ratio	CARMIL1 CDH23 ITGA2B HDAC7 KLF2 TLE4 FKBPL	2.10e-03	363	144	7	EFO_0008446
Disease	IGFBP-3 measurement	SORCS2 GREB1 FHDC1	2.35e-03	54	144	3	EFO_0004626
Disease	Malignant neoplasm of breast	GDF10 MAP3K6 HDAC7 MICALL1 JAG2 KMT2D PRICKLE3 FKBPL ARRDC3 TNS1 NLRP8 ZNF646 FOXP3	2.38e-03	1074	144	13	C0006142
Disease	Colorectal Neoplasms	GRID1 PPOX KLF2 FBLN2 IGF2 CTBP1	2.45e-03	277	144	6	C0009404
Disease	cortical thickness	NFILZ ZNF385B GDF10 MICALL1 JAG2 BMP6 BMP7 IGF2 CEP112 KIAA1755 ELN TNS1 WNK2	3.22e-03	1113	144	13	EFO_0004840
Disease	angina pectoris	MIA3 CARMIL1 FHL1 PCSK9	3.34e-03	125	144	4	EFO_0003913
Disease	cytomegalovirus virus reactivation, response to allogeneic hematopoietic stem cell transplant	FAM209A CDH23	3.83e-03	19	144	2	EFO_0007044, EFO_0020106

Protein segments in the cluster

Peptide	Gene	Start	Entry
LRSPGTLPNHPNFRL	TDRD1	41	Q9BXT4
SPPGLRGGQLHSPLK	FAM209A	86	Q5JX71
DLQPAGSLPHAPRIK	CHTF18	86	Q8WVB6
APFPHSGLQGRPRLR	PABPN1L	246	A6NDY0
RGLGHPLRHLPLPQP	EPAS1	771	Q99814
PRGLLPTHVPASLGA	FBRSL1	306	Q9HCM7
PATPAGHPVSGLLLR	FBRSL1	791	Q9HCM7
NGPLHPRPLVALLDG	CTBP1	21	Q13363
PPSLGLLPGARVHFS	CTC1	956	Q2NKJ3
LFRPGPGSLHLKNGP	NEDD9	556	Q14511
GLPSVRPLLHCAPGF	COMP	81	P49747
FLLPKISHRGPQADP	FAM47DP	76	A6NHR8
VFHLARLGALPLPCP	GPR25	266	O00155
PGLDPFPRHGGLALQ	ATN1	966	P54259
PRILIHGLQGASEPP	BARHL1	296	Q9BZE3
LHPIKLQPQRGGPGR	AJM1	146	C9J069
GPFTHRPEPGTLKIL	CEP112	81	Q8N8E3
FLVSNHRPPQPLKGR	CA13	241	Q8N1Q1
SGLPPLLGVVTRHPA	CCDC87	376	Q9NVE4
CAQRLPLLPGHPGLF	FBN3	346	Q75N90
ILGLPHRPRPHLQGK	BMP7	61	P18075
PGQGSLRFRHKPPVE	CDH23	3261	Q9H251
AALHPAPLRIFPGLA	DANCR	16	P0C864
PLVIGTIPLHPFGSR	ARRDC3	306	Q96B67
RRHGPLSKLYGRAPP	ATXN7L2	101	Q5T6C5
HRLEVAGPRKGPLSP	POLM	121	Q9NP87
GFRLKPPTLIHGQAP	RANBP3	141	Q9H6Z4
LTRGGLQQPPHLPAG	RBM33	1026	Q96EV2
RFGLPSPDHVLGLPV	CYB5R2	36	Q6BCY4
PEGLGQPSLPHKLRI	NFILZ	256	A0A5F9ZHS7
PLRLSGRHFPKSIPA	PGBD4	516	Q96DM1
LHVLLPARGPGPPQR	JAK3	26	P52333
PTLLHAGFLPPVVRG	NPAS1	521	Q99742
LVYPHLQRLGPGPAL	NPAS1	551	Q99742
HGSRLLPGALPFARP	PTPRN2	406	Q92932
LGLLPRGQHPNPLRE	PAFAH1B3	136	Q15102
GAEGLLPFLHPRPIS	FHDC1	511	Q9C0D6
DLSGNRLHTLPPGLP	PODN	436	Q7Z5L7
GQLPALPAPGRFRHG	KLHL33	251	A6NCF5
PSGARLGPLPHLQAL	FOXP3	81	Q9BZS1
FHPRRLLLSGPPQIG	GREB1	1336	Q4ZG55
GPPFLKALAAALRHP	NLRP8	716	Q86W28
HLLRPGPGPEGLRQL	NFKBID	286	Q8NI38
PFLGLHIASPPNFRL	MAPK8IP1	21	Q9UQF2
PPTPGLKFSFLRGQR	KIAA1755	466	Q5JYT7
LNPIRNPIERPGGHK	JAG2	1131	Q9Y219
QSGPGPARPVLLLHA	IL17RE	481	Q8NFR9
QTHLPGKRPARGSLP	KDM8	146	Q8N371
HGPGLSAPQSLVPLR	BSN	2131	Q9UPA5
PLPLGPPTRQHLLFR	GDF10	161	P55107
LGPALLHRPLFAFPD	MAP3K6	1071	O95382
GLLVPAHIFRIGPAP	FBLN2	1096	P98095
LGTHKPPVLRPRGQP	PCSK9	571	Q8NBP7
PDGPPLKDNLGLRHR	MKX	46	Q8IYA7
LRHSPGPGGQRLLLP	PCDH1	26	Q08174
HVPPLSRGLPASLLG	PGPEP1L	146	A6NFU8
APLPAPGLSHRDLGQ	C19orf85	151	A0A1B0GUS0
IFRLGHLLPGRAKGP	NPHS2	136	Q9NP85
DRAGLGPPKLSHRPQ	MNT	346	Q99583
RRFPGPAGILPHQQS	HROB	396	Q8N3J3
NGRLHELPVPKPRGT	MICALL1	341	Q8N3F8
ELPLGQAPPHLLARG	IL17C	41	Q9P0M4
LPARPHRGLSTFPGA	NSUN5P1	121	Q3KNT7
GPEPKRRHLGTLLQP	HCN3	41	Q9P1Z3
GVLNRFVPGRHPPEK	HSPA12B	546	Q96MM6
PGHGVQLPSGRLLVP	NEU4	161	Q8WWR8
FLRKSLGPLGIGPLH	OC90	461	Q02509
FHPRRLLLTGPPQVG	GREB1L	1311	Q9C091
GHSPLRAIAQPGPIL	HELZ	1461	P42694
QLAFSGPKLAPRLGP	CASKIN2	1111	Q8WXE0
FPPGHHPRRVLGLQD	LRIT1	186	Q9P2V4
PSLLPRFDGLHGQPG	PCF11	1046	O94913
GFFLGERIPLPPHLC	PRICKLE3	561	O43900
PHLGLRISGTPLGIF	LINC00472	111	Q9H8W2
PLTLFPSANLRGRHP	FHL1	256	Q13642
NKGLLARIFGAPPPS	ABT1	246	Q9ULW3
GPQGLHLLFERPRPP	FBRS	331	Q9HAH7
STLPPGGLANLHPRL	HECTD1	2546	Q9ULT8
QLPGHSGPPVRLTLA	FKBPL	176	Q9UIM3
LRKRPAEPSPQIHGG	FER1L6-AS2	66	Q96M78
RIQPPLGFGKLCPHR	CACNA1C	1571	Q13936
GVPLGPHRLLSSIPI	GBGT1	156	Q8N5D6
PGLSGLVHPSAQRPR	GFRA4	161	Q9GZZ7
ALPGPFPGGRVVRLH	EIF3F	81	O00303
AGALPHINARGPVRP	CCDC3	251	Q9BQI4
PQPLELEHPTRGKLG	BATF2	206	Q8N1L9
SALLPHGAPGLRKVP	CRYBG2	931	Q8N1P7
HGAPGLRKVPGQLPL	CRYBG2	936	Q8N1P7
GKGAPRLPPTLLDQF	DLGAP3	111	O95886
LPPQGRSRGFAGLHP	FAM120C	936	Q9NX05
RPLIALPTQDPAHGG	IGF2	156	P01344
VLGLPHRPRPLHGLQ	BMP6	86	P22004
PGAAHPLNRKSLLAP	BMP6	176	P22004
SERLPQKPLHRGGGP	AKNA	896	Q7Z591
NGQPFPAHRPVGLRV	AREL1	86	O15033
LHLLGKEGPRTPVPS	COPG2	456	Q9UBF2
RGHLLPSVPRSKANP	CFAP126	46	Q5VTH2
MQLPGPGLRSFHPLA	MAN2A2	1031	P49641
IPHLFVQRNPGGSPR	GRID1	111	Q9ULK0
AVPKLHPGLPENRFG	CARMIL1	1211	Q5VZK9
LLTVPGLGPLPFHFA	HDAC7	321	Q8WUI4
SLALGLPHLPSPKQR	CCDC28B	36	Q9BUN5
PRGPPGHIKVLSNSL	COL15A1	791	P39059
LLLSILHPSRPGGVP	ELN	16	P15502
PSGLSLHLRPPSRGN	FAM53C	71	Q9NYF3
LSGPPRKPQESRGHV	RUBCN	251	Q92622
ERQRHIGKPLLGGPF	SCO1	126	O75880
PFHFQLSPRLPELGR	CDH15	516	P55291
RIQPPLGFGKLCPHR	CACNA1D	1511	Q01668
LPLSPRGHQPGRLST	REM1	21	O75628
GRGPGAPKRHNPFLL	RUSC2	91	Q8N2Y8
RPPVLFRLTPRQGGH	RTL5	546	Q5HYW3
LGFPIGTPAPARHKI	SZT2	666	Q5T011
FEQAHALLLRGRPPP	PLEKHH3	516	Q7Z736
RDLPLHPRGFLPGHA	MIA3	1826	Q5JRA6
SPGPHALLLVVPLGR	GIMAP4	111	Q9NUV9
LRVLPSSLPGHAPGL	SYNPO	201	Q8N3V7
LRPLGATFPGPIFHL	NBEAL2	2591	Q6ZNJ1
ARGLHPRPSILQPGP	FAM120AOS	46	Q5T036
RSPEPGRLGPHAQLT	SORCS2	51	Q96PQ0
LAKASFGRPPHLIGP	SHROOM4	391	Q9ULL8
GLLPNHRPRLPEGVV	MRPS18A	126	Q9NVS2
HVALGPHLRPPFLGV	SAMD11	306	Q96NU1
HGIFGPRDPQLVPIL	NSDHL	201	Q15738
RPSLPLPHFNKHLLG	WDR18	331	Q9BV38
LFLQPRGPHALGAPS	ITGA2B	361	P08514
VALPFLPEAHPLRGG	EXTL1	196	Q92935
RPKPRTLGPQAHSLA	SSBP3-AS1	76	Q7Z2R9
PGVFLHPRPLPRVQL	B4GALNT4	551	Q76KP1
RELPGRHLPGQKTPT	LINC00615	71	Q96LM1
QLAQPHLGGILDPRP	TRAK1	591	Q9UPV9
LSNLGHPESPPRKRL	SKP2	56	Q13309
HALPTGLRGLLRPSP	PPOX	106	P50336
VHLSLRPIFLQPGRP	PDCD11	341	Q14690
LPPHLLGRLQGQPLR	ZSCAN10	41	Q96SZ4
LGLPPIGQRALHYLG	TMC8	581	Q8IU68
VPPALLRHLFNCGRP	NOD2	621	Q9HC29
PDALIGPGIPRHARQ	TLE4	466	Q04727
LTIALNPGGRPKEPH	TNS1	931	Q9HBL0
LLLPEAGRPALSPGH	VWCE	286	Q96DN2
LPTRQREGLASHPGP	ZNF646	166	O15015
KLFRLSPGHAAPLLP	PRRT4	636	C9JH25
RLPFSGHRAPPALLT	SEMA6C	851	Q9H3T2
GHRAPPALLTRVPSG	SEMA6C	856	Q9H3T2
PHNLGIVFGPTLFRP	ARHGAP9	706	Q9BRR9
VFRHGARSPLKPLPL	ACP6	56	Q9NPH0
PLPGKAFLRQLPFRG	SNX3	91	O60493
IQRPPFRFPKGGHLL	SGSM1	346	Q2NKQ1
LLRPGHGPIRATPAS	ZNF385B	451	Q569K4
RGPLAKHRLVPPAQG	TRIM9	201	Q9C026
RLHLSPVGIPGSARP	PLEKHG2	86	Q9H7P9
IHNKLGLPGIPRPTF	TEAD1	136	P28347
RRLGKPLPPNVGFFH	WNK2	1961	Q9Y3S1
HIRPGVKQAPRPSGA	ABI3BP	666	Q7Z7G0
RLTGKPGQVLPHPEL	SMYD5	86	Q6GMV2
LEARGLPPHLFGPLG	TRIP12	406	Q14669
LHPLFSGRPPTLGLL	UPK3B	231	Q9BT76
RTPLLQAPGGPHQDL	TCIRG1	151	Q13488
LRKGAEVPQGPPLSH	nan	136	Q6ZTC4
HRILSGRPPLGFLNP	TPP1	491	O14773
PALHGRFLLAPPGRL	KLF2	106	Q9Y5W3
ALHLRIPPQPGALGS	KMT2D	2101	O14686