Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	secondary active organic cation transmembrane transporter activity	SLC22A1 SLC22A4	3.34e-06	2	37	2	GO:0008513
GeneOntologyMolecularFunction	dihydrosphingosine-1-phosphate phosphatase activity	SGPP1 SGPP2	3.34e-06	2	37	2	GO:0070780
GeneOntologyMolecularFunction	acetate ester transmembrane transporter activity	SLC22A1 SLC22A4	2.00e-05	4	37	2	GO:1901375
GeneOntologyMolecularFunction	acetylcholine transmembrane transporter activity	SLC22A1 SLC22A4	2.00e-05	4	37	2	GO:0005277
GeneOntologyMolecularFunction	carnitine transmembrane transporter activity	SLC22A1 SLC22A4	4.99e-05	6	37	2	GO:0015226
GeneOntologyMolecularFunction	sphingosine-1-phosphate phosphatase activity	SGPP1 SGPP2	6.97e-05	7	37	2	GO:0042392
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	SCNN1A KCNJ18 KCNJ12 TMEM63A	1.28e-04	140	37	4	GO:0099094
GeneOntologyMolecularFunction	RNA 7-methylguanosine cap binding	CYFIP1 CYFIP2	3.00e-04	14	37	2	GO:0000340
GeneOntologyMolecularFunction	quaternary ammonium group transmembrane transporter activity	SLC22A1 SLC22A4	3.46e-04	15	37	2	GO:0015651
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	SCNN1A KCNJ18 KCNJ12 TMEM63A	4.35e-04	193	37	4	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	SCNN1A KCNJ18 KCNJ12 TMEM63A	4.70e-04	197	37	4	GO:0022834
GeneOntologyMolecularFunction	lipid phosphatase activity	SGPP1 SGPP2	5.60e-04	19	37	2	GO:0042577
GeneOntologyMolecularFunction	RNA cap binding	CYFIP1 CYFIP2	6.86e-04	21	37	2	GO:0000339
GeneOntologyMolecularFunction	neurotransmitter transmembrane transporter activity	SLC22A1 SLC22A4	6.86e-04	21	37	2	GO:0005326
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SCNN1A TCIRG1 KCNJ18 SLC22A1 KCNJ12 TMEM63A	9.49e-04	627	37	6	GO:0022890
GeneOntologyMolecularFunction	transmembrane transporter activity	SCNN1A TCIRG1 KCNJ18 SLC16A2 SLC22A1 SLC22A4 KCNJ12 TMEM63A	1.21e-03	1180	37	8	GO:0022857
GeneOntologyMolecularFunction	inward rectifier potassium channel activity	KCNJ18 KCNJ12	1.23e-03	28	37	2	GO:0005242
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SCNN1A TCIRG1 KCNJ18 SLC22A1 KCNJ12 TMEM63A	1.28e-03	664	37	6	GO:0008324
GeneOntologyMolecularFunction	PDZ domain binding	KCNJ18 SLC22A4 KCNJ12	1.52e-03	123	37	3	GO:0030165
GeneOntologyMolecularFunction	modified amino acid transmembrane transporter activity	SLC22A1 SLC22A4	1.70e-03	33	37	2	GO:0072349
GeneOntologyMolecularFunction	transporter activity	SCNN1A TCIRG1 KCNJ18 SLC16A2 SLC22A1 SLC22A4 KCNJ12 TMEM63A	2.12e-03	1289	37	8	GO:0005215
GeneOntologyMolecularFunction	microfilament motor activity	MYO1G MYO9A	2.25e-03	38	37	2	GO:0000146
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SCNN1A TCIRG1 KCNJ18 SLC22A1 KCNJ12 TMEM63A	2.49e-03	758	37	6	GO:0015318
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SCNN1A TCIRG1 KCNJ18 SLC22A1 KCNJ12 TMEM63A	3.12e-03	793	37	6	GO:0015075
GeneOntologyMolecularFunction	gated channel activity	SCNN1A KCNJ18 KCNJ12 TMEM63A	3.29e-03	334	37	4	GO:0022836
GeneOntologyMolecularFunction	monoatomic cation channel activity	SCNN1A KCNJ18 KCNJ12 TMEM63A	3.61e-03	343	37	4	GO:0005261
GeneOntologyBiologicalProcess	import across plasma membrane	SCNN1A KCNJ18 SLC16A2 SLC22A4 KCNJ12	4.69e-05	230	36	5	GO:0098739
GeneOntologyBiologicalProcess	carnitine transmembrane transport	SLC22A1 SLC22A4	6.19e-05	7	36	2	GO:1902603
GeneOntologyBiologicalProcess	positive regulation of neurotrophin TRK receptor signaling pathway	CYFIP1 CYFIP2	8.24e-05	8	36	2	GO:0051388
GeneOntologyBiologicalProcess	carnitine transport	SLC22A1 SLC22A4	1.06e-04	9	36	2	GO:0015879
GeneOntologyCellularComponent	apical plasma membrane	SCNN1A TCIRG1 CASR SLC16A2 SLC22A1 SLC22A4 CRB1	2.00e-05	487	37	7	GO:0016324
GeneOntologyCellularComponent	apical part of cell	SCNN1A TCIRG1 CASR SLC16A2 SLC22A1 SLC22A4 CRB1	6.93e-05	592	37	7	GO:0045177
GeneOntologyCellularComponent	SCAR complex	CYFIP1 CYFIP2	1.99e-04	12	37	2	GO:0031209
Domain	Cytoplasmic_FMR1-int	CYFIP1 CYFIP2	3.61e-06	2	36	2	IPR008081
Domain	FragX_IP	CYFIP1 CYFIP2	3.61e-06	2	36	2	PF05994
Domain	K_chnl_inward-rec_Kir2.2	KCNJ18 KCNJ12	3.61e-06	2	36	2	IPR003272
Domain	K_chnl_inward-rec_Kir_N	KCNJ18 KCNJ12	1.08e-05	3	36	2	IPR013673
Domain	IRK_N	KCNJ18 KCNJ12	1.08e-05	3	36	2	PF08466
Domain	DUF1394	CYFIP1 CYFIP2	2.16e-05	4	36	2	PF07159
Domain	DUF1394	CYFIP1 CYFIP2	2.16e-05	4	36	2	IPR009828
Domain	Orgcat_transp/SVOP	SLC22A1 SLC22A4	1.29e-04	9	36	2	IPR004749
Domain	K_chnl_inward-rec_Kir_cyto	KCNJ18 KCNJ12	4.26e-04	16	36	2	IPR013518
Domain	IRK	KCNJ18 KCNJ12	4.26e-04	16	36	2	PF01007
Domain	-	KCNJ18 KCNJ12	4.26e-04	16	36	2	2.60.40.1400
Domain	K_chnl_inward-rec_Kir	KCNJ18 KCNJ12	4.26e-04	16	36	2	IPR016449
Domain	-	SGPP1 SGPP2	5.42e-04	18	36	2	1.20.144.10
Domain	acidPPc	SGPP1 SGPP2	5.42e-04	18	36	2	SM00014
Domain	P_Acid_Pase_2/haloperoxidase	SGPP1 SGPP2	6.72e-04	20	36	2	IPR000326
Domain	PAP2	SGPP1 SGPP2	6.72e-04	20	36	2	PF01569
Domain	SUGAR_TRANSPORT_1	SLC22A1 SLC22A4	9.71e-04	24	36	2	PS00216
Domain	MFS	SLC16A2 SLC22A1 SLC22A4	1.17e-03	108	36	3	PS50850
Domain	hEGF	FBN2 CRB1	1.32e-03	28	36	2	PF12661
Domain	Sugar_transporter_CS	SLC22A1 SLC22A4	1.73e-03	32	36	2	IPR005829
Domain	MFS_dom	SLC16A2 SLC22A1 SLC22A4	2.17e-03	134	36	3	IPR020846
Domain	Sugar_tr	SLC22A1 SLC22A4	2.18e-03	36	36	2	PF00083
Domain	MFS_sugar_transport-like	SLC22A1 SLC22A4	2.18e-03	36	36	2	IPR005828
Domain	MYOSIN_MOTOR	MYO1G MYO9A	2.43e-03	38	36	2	PS51456
Domain	Myosin_head	MYO1G MYO9A	2.43e-03	38	36	2	PF00063
Domain	Myosin_head_motor_dom	MYO1G MYO9A	2.43e-03	38	36	2	IPR001609
Domain	MYSc	MYO1G MYO9A	2.43e-03	38	36	2	SM00242
Domain	IQ	MYO9A UBE3B	8.26e-03	71	36	2	PF00612
Domain	MFS	SLC16A2 SLC22A4	9.65e-03	77	36	2	IPR011701
Domain	MFS_1	SLC16A2 SLC22A4	9.65e-03	77	36	2	PF07690
Domain	IQ	MYO9A UBE3B	1.06e-02	81	36	2	SM00015
Domain	EGF-like_dom	FBN2 IMPG1 CRB1	1.21e-02	249	36	3	IPR000742
Domain	IQ_motif_EF-hand-BS	MYO9A UBE3B	1.30e-02	90	36	2	IPR000048
Domain	IQ	MYO9A UBE3B	1.38e-02	93	36	2	PS50096
Domain	EGF_Ca-bd_CS	FBN2 CRB1	1.50e-02	97	36	2	IPR018097
Domain	EGF_CA	FBN2 CRB1	1.56e-02	99	36	2	PS01187
Domain	ASX_HYDROXYL	FBN2 CRB1	1.59e-02	100	36	2	PS00010
Domain	Ig_E-set	KCNJ18 KCNJ12	1.71e-02	104	36	2	IPR014756
Pathway	WP_BIOSYNTHESIS_AND_TURNOVER_OF_1DEOXYSPHINGOID_BASES	SGPP1 SGPP2	1.39e-04	8	32	2	M45534
Pathway	REACTOME_ORGANIC_CATION_TRANSPORT	SLC22A1 SLC22A4	1.39e-04	8	32	2	MM15191
Pathway	REACTOME_ORGANIC_CATION_TRANSPORT	SLC22A1 SLC22A4	2.22e-04	10	32	2	M27450
Pathway	REACTOME_SPHINGOLIPID_CATABOLISM	SGPP1 SGPP2	3.25e-04	12	32	2	M48264
Pathway	REACTOME_SPHINGOLIPID_CATABOLISM	SGPP1 SGPP2	3.25e-04	12	32	2	MM17238
Pathway	REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT	SLC22A1 SLC22A4	3.25e-04	12	32	2	MM15192
Pathway	REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT	SLC22A1 SLC22A4	5.15e-04	15	32	2	M888
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	DERL2 SCNN1A TCIRG1 SLC16A2 AVPR2 SLC22A1 SLC22A4	6.95e-04	681	32	7	MM14985
Pathway	REACTOME_PHASE_4_RESTING_MEMBRANE_POTENTIAL	KCNJ18 KCNJ12	8.33e-04	19	32	2	MM15194
Pathway	KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPE_TO_RAC_SIGNALING_PATHWAY	CYFIP1 CYFIP2	9.25e-04	20	32	2	M47737
Pathway	WP_METABOLISM_OF_SPHINGOLIPIDS_IN_ER_AND_GOLGI_APPARATUS	SGPP1 SGPP2	1.02e-03	21	32	2	M39459
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	DERL2 SCNN1A TCIRG1 SLC16A2 AVPR2 SLC22A1 SLC22A4	1.10e-03	736	32	7	M27287
Pathway	KEGG_MEDICUS_REFERENCE_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY	CYFIP1 CYFIP2	1.45e-03	25	32	2	M47716
Pathway	WP_SPHINGOLIPID_METABOLISM_OVERVIEW	SGPP1 SGPP2	1.45e-03	25	32	2	MM15931
Pathway	WP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY	SGPP1 SGPP2	1.57e-03	26	32	2	M39784
Pathway	WP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY	SGPP1 SGPP2	1.57e-03	26	32	2	MM15892
Pathway	WP_SPHINGOLIPID_METABOLISM_OVERVIEW	SGPP1 SGPP2	1.69e-03	27	32	2	M39863
Pathway	KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPGD_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY	CYFIP1 CYFIP2	1.95e-03	29	32	2	M47717
Pathway	KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY	CYFIP1 CYFIP2	2.09e-03	30	32	2	M47738
Pathway	REACTOME_ACTIVATION_OF_G_PROTEIN_GATED_POTASSIUM_CHANNELS	KCNJ18 KCNJ12	2.09e-03	30	32	2	MM14542
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_WASPS_AND_WAVES	CYFIP1 CYFIP2	2.68e-03	34	32	2	MM15265
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_WASPS_AND_WAVES	CYFIP1 CYFIP2	3.00e-03	36	32	2	M27549
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	KCNJ18 KCNJ12	3.00e-03	36	32	2	MM14544
Pathway	KEGG_SPHINGOLIPID_METABOLISM	SGPP1 SGPP2	3.51e-03	39	32	2	M15955
Pubmed	Identification and characterization of a novel human sphingosine-1-phosphate phosphohydrolase, hSPP2.	SGPP1 SGPP2	1.10e-06	2	37	2	12411432
Pubmed	Role of Kir2.2 in hypercapnic ventilatory response during postnatal development of mouse.	KCNJ18 KCNJ12	1.10e-06	2	37	2	15705530
Pubmed	Different dysregulations of CYFIP1 and CYFIP2 in distinct types of dementia.	CYFIP1 CYFIP2	1.10e-06	2	37	2	38128786
Pubmed	Sphingosine-1-phosphate Phosphatase 2 Regulates Pancreatic Islet β-Cell Endoplasmic Reticulum Stress and Proliferation.	SGPP1 SGPP2	1.10e-06	2	37	2	27059959
Pubmed	Cytoplasmic FMR1 interacting protein (CYFIP) family members and their function in neural development and disorders.	CYFIP1 CYFIP2	1.10e-06	2	37	2	34327661
Pubmed	C57BL/6N mutation in cytoplasmic FMRP interacting protein 2 regulates cocaine response.	CYFIP1 CYFIP2	1.10e-06	2	37	2	24357318
Pubmed	Cytoplasmic FMRP interacting protein 1/2 (CYFIP1/2) expression analysis in autism.	CYFIP1 CYFIP2	1.10e-06	2	37	2	29752658
Pubmed	Protein interactome and cell-type expression analyses reveal that cytoplasmic FMR1-interacting protein 1 (CYFIP1), but not CYFIP2, associates with astrocytic focal adhesion.	CYFIP1 CYFIP2	1.10e-06	2	37	2	35567753
Pubmed	Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics.	SLC22A1 SLC22A4	1.10e-06	2	37	2	17609683
Pubmed	Cyfip1 Haploinsufficiency Increases Compulsive-Like Behavior and Modulates Palatable Food Intake in Mice: Dependence on Cyfip2 Genetic Background, Parent-of Origin, and Sex.	CYFIP1 CYFIP2	1.10e-06	2	37	2	31324746
Pubmed	Relationship Between SLC22A1 and SLC22A4 Gene Polymorphisms and Risk of Type 2 Diabetes in Chinese Han Population.	SLC22A1 SLC22A4	1.10e-06	2	37	2	30274012
Pubmed	Molecular cloning and functional expression of cDNA encoding a second class of inward rectifier potassium channels in the mouse brain.	KCNJ18 KCNJ12	3.30e-06	3	37	2	8083233
Pubmed	The consequences of disrupting cardiac inwardly rectifying K(+) current (I(K1)) as revealed by the targeted deletion of the murine Kir2.1 and Kir2.2 genes.	KCNJ18 KCNJ12	3.30e-06	3	37	2	11410627
Pubmed	Low-affinity spermine block mediating outward currents through Kir2.1 and Kir2.2 inward rectifier potassium channels.	KCNJ18 KCNJ12	3.30e-06	3	37	2	17640933
Pubmed	Targeted disruption of Kir2.1 and Kir2.2 genes reveals the essential role of the inwardly rectifying K(+) current in K(+)-mediated vasodilation.	KCNJ18 KCNJ12	3.30e-06	3	37	2	10904001
Pubmed	Assignment of the murine inward rectifier potassium channel Irk2 (Kir2.2) gene to the central region of mouse chromosome 11.	KCNJ18 KCNJ12	6.60e-06	4	37	2	8921409
Pubmed	Interchangeable functions of Arabidopsis PIROGI and the human WAVE complex subunit SRA1 during leaf epidermal development.	CYFIP1 CYFIP2	6.60e-06	4	37	2	15294869
Pubmed	Transport of gabapentin by LAT1 (SLC7A5).	SLC22A1 SLC22A4	6.60e-06	4	37	2	23567998
Pubmed	Retrolinkin recruits the WAVE1 protein complex to facilitate BDNF-induced TrkB endocytosis and dendrite outgrowth.	CYFIP1 CYFIP2	6.60e-06	4	37	2	27605705
Pubmed	Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN.	CYFIP1 CYFIP2	6.60e-06	4	37	2	20228810
Pubmed	Functional characterization of inward rectifier potassium ion channel in murine fetal ventricular cardiomyocytes.	KCNJ18 KCNJ12	6.60e-06	4	37	2	20798526
Pubmed	A Soluble Epoxide Hydrolase Inhibitor Upregulated KCNJ12 and KCNIP2 by Downregulating MicroRNA-29 in a Mouse Model of Myocardial Infarction.	KCNJ18 KCNJ12	6.60e-06	4	37	2	32990585
Pubmed	Anti-hyperalgesic and anti-inflammatory effects of 4R-tobacco cembranoid in a mouse model of inflammatory pain.	CYFIP2 CRB1	1.10e-05	5	37	2	38267952
Pubmed	Staphylococcus aureus stimulates neutrophil itaconate production that suppresses the oxidative burst.	CYFIP2 CRB1	1.10e-05	5	37	2	36724077
Pubmed	Dendritic excitability of mouse frontal cortex pyramidal neurons is shaped by the interaction among HCN, Kir2, and Kleak channels.	KCNJ18 KCNJ12	1.10e-05	5	37	2	16177047
Pubmed	Differential cell-type-expression of CYFIP1 and CYFIP2 in the adult mouse hippocampus.	CYFIP1 CYFIP2	1.65e-05	6	37	2	31853374
Pubmed	A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P.	CYFIP1 CYFIP2	1.65e-05	6	37	2	11438699
Pubmed	Low renal mineralocorticoid receptor expression at birth contributes to partial aldosterone resistance in neonates.	SCNN1A AVPR2	1.65e-05	6	37	2	19477942
Pubmed	Genetic mapping refines DFNB3 to 17p11.2, suggests multiple alleles of DFNB3, and supports homology to the mouse model shaker-2.	KCNJ18 KCNJ12	1.65e-05	6	37	2	9529344
Pubmed	The inward rectifier potassium channel family.	KCNJ18 KCNJ12	1.65e-05	6	37	2	7580148
Pubmed	Smaller Body Size, Early Postnatal Lethality, and Cortical Extracellular Matrix-Related Gene Expression Changes of Cyfip2-Null Embryonic Mice.	CYFIP1 CYFIP2	2.30e-05	7	37	2	30687000
Pubmed	Gamma motor neurons survive and exacerbate alpha motor neuron degeneration in ALS.	KCNJ18 KCNJ12	3.07e-05	8	37	2	27930290
Pubmed	The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin.	SLC22A1 SLC22A4	3.07e-05	8	37	2	19536068
Pubmed	RNA-Seq reveals different mRNA abundance of transporters and their alternative transcript isoforms during liver development.	SLC22A1 SLC22A4	3.95e-05	9	37	2	22454430
Pubmed	Neurodevelopmental disorder-associated CYFIP2 regulates membraneless organelles and eIF2α phosphorylation via protein interactors and actin cytoskeleton.	CYFIP1 CYFIP2	3.95e-05	9	37	2	38981622
Pubmed	Abi1 is essential for the formation and activation of a WAVE2 signalling complex.	CYFIP1 CYFIP2	4.93e-05	10	37	2	15048123
Pubmed	A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels.	KCNJ18 KCNJ12	4.93e-05	10	37	2	14960569
Pubmed	Dynamic regulation of sphingosine-1-phosphate homeostasis during development of mouse metanephric kidney.	SGPP1 SGPP2	6.02e-05	11	37	2	19073640
Pubmed	Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity.	CYFIP2 CRB1	7.22e-05	12	37	2	32277911
Pubmed	A physical map of the mouse shaker-2 region contains many of the genes commonly deleted in Smith-Magenis syndrome (del17p11.2p11.2).	KCNJ18 KCNJ12	8.53e-05	13	37	2	10049592
Pubmed	Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa.	SLC22A1 SLC22A4	8.53e-05	13	37	2	15369770
Pubmed	Deficiency of the neurodevelopmental disorder-associated gene Cyfip2 alters the retinal ganglion cell properties and visual acuity.	CYFIP1 CYFIP2	8.53e-05	13	37	2	34508581
Pubmed	Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier.	SLC22A1 SLC22A4	1.31e-04	16	37	2	35307651
Pubmed	In mouse brain profilin I and profilin II associate with regulators of the endocytic pathway and actin assembly.	CYFIP1 CYFIP2	1.67e-04	18	37	2	9463375
Pubmed	PITX2 insufficiency leads to atrial electrical and structural remodeling linked to arrhythmogenesis.	KCNJ18 KCNJ12	1.67e-04	18	37	2	21511879
Pubmed	Expression patterns of the aquaporin gene family during renal development: influence of genetic variability.	SCNN1A AVPR2	1.86e-04	19	37	2	19367412
Pubmed	NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons.	CYFIP1 CYFIP2	2.51e-04	22	37	2	21946561
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	CYFIP2 CRB1	2.99e-04	24	37	2	32212159
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	ZDHHC7 SENP2 AVPR2	3.07e-04	123	37	3	26912792
Pubmed	Penetrance of craniofacial anomalies in mouse models of Smith-Magenis syndrome is modified by genomic sequence surrounding Rai1: not all null alleles are alike.	KCNJ18 KCNJ12	3.80e-04	27	37	2	17273973
Pubmed	Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain.	CYFIP1 MYO9A CYFIP2	4.77e-04	143	37	3	32560809
Pubmed	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	SCNN1A CASR SLC22A1	4.77e-04	143	37	3	20424473
Pubmed	Identification of interaction partners for individual SH3 domains of Fas ligand associated members of the PCH protein family in T lymphocytes.	MYO1G CYFIP2	5.02e-04	31	37	2	19041431
Pubmed	Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria.	KCNJ18 KCNJ12	5.02e-04	31	37	2	17473172
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	SEMA6A CYFIP1 PHIP CYFIP2	5.58e-04	358	37	4	32460013
Pubmed	In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype.	SGPP1 KCNJ18 KCNJ12	6.62e-04	160	37	3	23375831
Pubmed	Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development.	SGPP1 SGPP2	8.37e-04	40	37	2	21319224
Interaction	SOWAHA interactions	PAN2 PCGF5 PHIP	1.36e-05	27	35	3	int:SOWAHA
Cytoband	Ensembl 112 genes in cytogenetic band chr17p11	PIGL KCNJ18 KCNJ12	5.92e-04	203	37	3	chr17p11
Cytoband	Ensembl 112 genes in cytogenetic band chr6q14	IMPG1 PHIP	2.80e-03	97	37	2	chr6q14
Cytoband	Ensembl 112 genes in cytogenetic band chr5q23	SEMA6A FBN2	4.05e-03	117	37	2	chr5q23
GeneFamily	Sphingosine-1-phosphate phosphatases	SGPP1 SGPP2	2.15e-06	2	27	2	1070
GeneFamily	Potassium voltage-gated channel subfamily J	KCNJ18 KCNJ12	2.54e-04	16	27	2	276
GeneFamily	G protein-coupled receptors, Class A orphans	MRGPRX4 GPR174	6.01e-03	78	27	2	262
GeneFamily	Solute carriers	SLC16A2 SLC22A1 SLC22A4	2.05e-02	395	27	3	752
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A CASR AVPR2 CYFIP2 SGPP2	4.98e-07	190	37	5	68ba1934b2b3f0cec8efd229fe1db6e8be8a26b0
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A CASR AVPR2 CYFIP2 SGPP2	4.98e-07	190	37	5	010d7d13a3c16e614c36720ef690a505b9f3f7aa
ToppCell	facs-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASR AVPR2 CYFIP2 SGPP2	1.23e-05	172	37	4	87a30a219b0a6979abb5fba292a2d8ea946fd849
ToppCell	facs-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASR AVPR2 CYFIP2 SGPP2	1.23e-05	172	37	4	5030ac31709cac236bb58f4ef9d545d24690411a
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A CYFIP2 SLC22A4 SGPP2	1.64e-05	185	37	4	af86e75096c1812ae27a78405355957ee8043d84
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SCNN1A CASR CYFIP2 SGPP2	1.71e-05	187	37	4	7ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A CASR CYFIP2 SGPP2	1.75e-05	188	37	4	14e120b20e76baa07b6510a94f0c2dcdfdd52357
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SCNN1A CASR CYFIP2 SGPP2	1.75e-05	188	37	4	3cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SCNN1A CASR CYFIP2 SGPP2	1.79e-05	189	37	4	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	CASR FRY MYO9A CYFIP2	1.79e-05	189	37	4	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A CASR CYFIP2 SGPP2	1.79e-05	189	37	4	443359d90fafae0c1de6bdcce9e8c95df6ea4de8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SCNN1A CASR MYO9A SGPP2	1.82e-05	190	37	4	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A CASR CYFIP2 SGPP2	1.82e-05	190	37	4	c247562df3e1aa3173c9f01a74d5831f0764a1b2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SCNN1A CASR MYO9A SGPP2	1.82e-05	190	37	4	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A CASR CYFIP2 SGPP2	1.82e-05	190	37	4	5cea8298c8336c136ba009630c9e48d4bc832cb2
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A CASR CYFIP2 SGPP2	1.86e-05	191	37	4	297bc79adc5fef211497819b4861b52cd26ac754
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A CASR CYFIP2 SGPP2	1.86e-05	191	37	4	e1ec165ba6578cefd88895e7e183190e79f733a4
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A CASR CYFIP2 SGPP2	1.90e-05	192	37	4	61c2caf6c838132ed5faa8791c288f2149eba2c8
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A CASR CYFIP2 SGPP2	1.90e-05	192	37	4	e19e3e8edcc08e4a67873bfb6e46489ca6c8756a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SCNN1A MYO9A CYFIP2 SGPP2	1.98e-05	194	37	4	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SCNN1A CASR MYO9A CYFIP2	2.02e-05	195	37	4	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	COVID-19_Mild-Non-classical_Monocyte\|COVID-19_Mild / Disease condition and Cell class	SGPP1 GPR174 PCGF5 CYFIP2	2.02e-05	195	37	4	dd00facd20a661ef23fa7fd9a02ee377b8f2d1b9
ToppCell	COVID-19_Mild-Non-classical_Monocyte-\|COVID-19_Mild / Disease condition and Cell class	SGPP1 GPR174 PCGF5 CYFIP2	2.02e-05	195	37	4	0295d9897830987eec74f51178e14fb0a83723dc
ToppCell	Control-Non-classical_Monocyte-\|Control / Disease condition and Cell class	SGPP1 MYO1G PCGF5 CYFIP2	2.06e-05	196	37	4	b17ab094cdc7050c2997e24ed474779b5d6f6146
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	SCNN1A CASR MYO9A SGPP2	2.06e-05	196	37	4	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SCNN1A MYO9A CYFIP2 SGPP2	2.06e-05	196	37	4	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	Control-Non-classical_Monocyte\|Control / Disease condition and Cell class	SGPP1 MYO1G PCGF5 CYFIP2	2.06e-05	196	37	4	404064ccfe2cb73df7a7f88aa65d86b97dcef9d4
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SCNN1A MYO9A PHIP CRB1	2.10e-05	197	37	4	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	droplet-Lung-1m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO1G SLC22A4 PAPOLG	1.63e-04	128	37	3	376102331d79010c1b2ce26e6ab0134c7b8a4ec3
ToppCell	droplet-Liver-LIVER-NPC-1m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRY GPR174 CYFIP2	2.75e-04	153	37	3	a8f83ec640fae51d4fba34b92e3d6cca4999e930
ToppCell	droplet-Lung-nan-3m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A MYO1G CYFIP2	2.75e-04	153	37	3	f6ef14d949107c08cb3690e26ec91e194cb43518
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GPR174 AVPR2 PCGF5	2.75e-04	153	37	3	0ad401cb70b9edfc6ae6ccba6879c6c2b6c4d296
ToppCell	mild_COVID-19_(asymptomatic)-NK_CD56bright\|World / disease group, cell group and cell class (v2)	SCNN1A PIGL GPR174	2.75e-04	153	37	3	aff5c8ab1fb4ebc324cec02cf562b7484bb10db8
ToppCell	droplet-Lung-nan-3m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A MYO1G CYFIP2	2.75e-04	153	37	3	6dcab3d50ab50051955204dc4e4a64c1ca855bcd
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO1G GPR174 AVPR2	2.91e-04	156	37	3	44ff0acdd5cc3575d6c24a1c2ba11cd9f55359d1
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO1G GPR174 AVPR2	2.91e-04	156	37	3	55ba43cec9d79f309e9f633a6469cf03bb621e64
ToppCell	facs-Lung-Endomucin-3m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A MYO1G CYFIP2	2.97e-04	157	37	3	0ad242320ada7bcb9e29548d3050bf4fd3a07115
ToppCell	facs-Lung-Endomucin-3m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A MYO1G CYFIP2	2.97e-04	157	37	3	fe4c9556806203e57522d1986754ebe5a20aa2de
ToppCell	Control-Myeloid-Monocytes,_Macrophages-Mast-cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SGPP1 MYO1G GPR174	3.08e-04	159	37	3	81782e9e370558d61af5e0c760ac9759d69fb725
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A MYO1G CYFIP2	3.14e-04	160	37	3	2020b6defbaf5b5db12af37f0103ac028a8ca76e
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A MYO1G CYFIP2	3.14e-04	160	37	3	af7cf0dc5fe7c02f7d6c436f6dde766c79ff0eae
ToppCell	lymphoid-B_cell-pro-B\|World / Lineage, cell class and subclass	TICRR SEMA6A SLC16A2	3.20e-04	161	37	3	23138e579f07d5a6f20d41457cb573b4ac95a4ef
ToppCell	droplet-Lung-3m-Hematologic-myeloid-non-classical_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCNN1A MYO1G CYFIP2	3.31e-04	163	37	3	f6c8db5963ee1f8e0c2996f1aeecd58c00e9b099
ToppCell	droplet-Liver-LIVER-NPC-1m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRY GPR174 CYFIP2	3.31e-04	163	37	3	66ecd544d7b52e61880b125bf39d1f406af6900a
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR174 SLC22A1 CYFIP2	3.31e-04	163	37	3	4af92b211d12c5b88b65bb746242cd702b545bd0
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR174 SLC22A1 CYFIP2	3.31e-04	163	37	3	d24774e0aa612322c22fdb3b314aef275fa01d68
ToppCell	droplet-Lung-3m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCNN1A MYO1G CYFIP2	3.37e-04	164	37	3	ea2897942ad72fba900c7ab354d6a9e203bf0e4a
ToppCell	facs-Heart-RA-24m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IMPG1 CYFIP2 SGPP2	3.43e-04	165	37	3	36415924d05373e9dd3665be599f4f3f40bf0497
ToppCell	lymphoid-B_cell-pro-B\|lymphoid / Lineage, cell class and subclass	TICRR SEMA6A SLC16A2	3.43e-04	165	37	3	8126c2f7810fc6e09b18783aadf6434ae12b0514
ToppCell	facs-Heart-RA-24m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IMPG1 CYFIP2 SGPP2	3.43e-04	165	37	3	56310fddd3d8e4afdfde066d26cee9747e5b8c6a
ToppCell	droplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCNN1A MYO1G CYFIP2	3.62e-04	168	37	3	d823979335ac6b5d1f062ebb741c759d2f919dbf
ToppCell	droplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCNN1A MYO1G CYFIP2	3.62e-04	168	37	3	4b5be7c6662eceddf90a65015f12908278d1664e
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SGPP1 MYO1G TMEM63A	3.62e-04	168	37	3	52fd65024af8683db11d931f7563cbe8eb815d1c
ToppCell	droplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCNN1A MYO1G CYFIP2	3.62e-04	168	37	3	689c41f6e9f65381570991cc311cba49a57ec955
ToppCell	droplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCNN1A MYO1G CYFIP2	3.62e-04	168	37	3	f377ff4c066a9857ad14d245e56325ad220e22e1
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A MYO1G CYFIP2	3.68e-04	169	37	3	411556e93adcbb7e4d79b02f3dc72963ec8a0759
ToppCell	droplet-Lung-nan-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A MYO1G CYFIP2	3.68e-04	169	37	3	c96e0f3241d13926dbee9f91c0c8c5bfa7479a0d
ToppCell	droplet-Lung-LUNG-30m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A MYO1G CYFIP2	3.68e-04	169	37	3	39b1acfd099abb9de18c29c05c7a67709ea76775
ToppCell	droplet-Lung-nan-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A MYO1G CYFIP2	3.68e-04	169	37	3	ba023ee7bb165c2bfbefc2d969ff32ca1eeed33b
ToppCell	E18.5-Immune-Immune_Myeloid-Granulocytic-Basophil\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO1G TICRR GPR174	3.68e-04	169	37	3	b23d0aaa2da333b9c69a7aee862d5a5d2a1bf79b
ToppCell	E18.5-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO1G TICRR GPR174	3.68e-04	169	37	3	83d1bcf33872b01ea9614f608a3e4ab30df25c7e
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A MYO1G CYFIP2	3.75e-04	170	37	3	8e774af244cfe787fa0ea2b6be0c3c2d00bfe4fc
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A MYO1G CYFIP2	3.75e-04	170	37	3	f5140eb9313c0d1bb31f8a761d9c062c56733a61
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TICRR AVPR2 TMEM63A	3.81e-04	171	37	3	913bae728b5e653771a27c79a309eb023699f1d0
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TICRR AVPR2 TMEM63A	3.81e-04	171	37	3	f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell	droplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCNN1A MYO1G CYFIP2	3.81e-04	171	37	3	00739085fdbc4d64c9faacba2c2adeab580dd2b1
ToppCell	lymphoid-B_cell-pro-B\|B_cell / Lineage, cell class and subclass	TICRR SEMA6A SLC16A2	3.88e-04	172	37	3	da1e2e54f442f5c2032c857c4812e9060f2053cd
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Red_blood_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCGF5 SLC22A4 CRB1	3.88e-04	172	37	3	cc1a45a35f78063b2a777ae905f70f894fbcb22f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1G GPR174 AVPR2	3.88e-04	172	37	3	2bbe3f601a56577d200aa7ba7031f7c19b988cc1
ToppCell	droplet-Lung-nan-21m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A MYO1G CYFIP2	3.88e-04	172	37	3	51bea97564a33f0060c546c9be4bf8bf8f1660f6
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Red_blood_cells-RBC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCGF5 SLC22A4 CRB1	3.88e-04	172	37	3	30c57f5ca2326e8d890d9aac8096c64e5b51a24f
ToppCell	droplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCNN1A MYO1G CYFIP2	3.88e-04	172	37	3	5f58ff6cac32546d07b2a49ed250b6c7aa417188
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1G GPR174 AVPR2	3.88e-04	172	37	3	3ffe721f62c0d20c1d765ecb15ed4e1aa88099f7
ToppCell	droplet-Lung-nan-21m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A MYO1G CYFIP2	3.88e-04	172	37	3	be4dd4ba8d7a651677c797c25fd75f14e627415a
ToppCell	droplet-Lung-LUNG-1m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A MYO1G CYFIP2	4.08e-04	175	37	3	c8cfe0ac0c1ac447c626a623cc49692a0b177a1c
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A MYO1G CYFIP2	4.08e-04	175	37	3	61fbd8f685d3daad46449e4c0386a38886496566
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-B_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LCN8 MYO1G GPR174	4.15e-04	176	37	3	d0a3e176df1270968efa79c00dc941c5e1c4f7aa
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-B_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LCN8 MYO1G GPR174	4.15e-04	176	37	3	274458d80f9f3f080248cbf64e4784ef351e7254
ToppCell	Control-Lymphocytic_NKT-T_cells-T-cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO1G GPR174 TMEM63A	4.29e-04	178	37	3	910f8bea19d335455aba24e6a07b4834b709db5d
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells-Pro-B\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LCN8 MYO1G CYFIP2	4.36e-04	179	37	3	223f0895da89c7606f637aef113912dd06f39c5a
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRY SEMA6A CYFIP2	4.36e-04	179	37	3	d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell	Control-Lymphocytic_NKT-T_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO1G GPR174 TMEM63A	4.36e-04	179	37	3	d892d9496f1c33e23312092591eb2e968e736f7d
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A CASR CYFIP2	4.43e-04	180	37	3	0b653b1b653b40f3b8711d1312029a4a8a4961db
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-SELL+_CD4_T\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCNN1A MYO1G GPR174	4.43e-04	180	37	3	702673c0b7c5b0d22a6af3884374804b8c4d6254
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CASR CYFIP2 CRB1	4.43e-04	180	37	3	40f79b4455dbd1c2720dc32d9d77c70f835cecb3
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A AVPR2 SGPP2	4.57e-04	182	37	3	2ef6889321fd0104d277518d130e19143b3af41c
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A AVPR2 SGPP2	4.57e-04	182	37	3	fe4fb213dc0ca482b0f94097fe1b0a51fc2690e2
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGPP1 SLC16A2 SLC22A1	4.57e-04	182	37	3	be8dd52898525ce6632af0adc2801944f3ac10bd
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A AVPR2 SGPP2	4.57e-04	182	37	3	75608f80fd570da499891dc02f8649d5428b896c
ToppCell	wk_15-18-Hematologic-Meg-ery\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PCGF5 SLC22A4 CRB1	4.57e-04	182	37	3	1adb8d6404d50155e9f9ba805abef63929fe865f
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGPP1 SLC16A2 SLC22A1	4.57e-04	182	37	3	faf0dfa3adc2d2706b6942b5127093ccdc856447
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A CYFIP2 SGPP2	4.65e-04	183	37	3	03c7e69136d5a3b9c5b2c91733e9b1c791f45c49
ToppCell	wk_15-18-Hematologic-Meg-ery-Definitive_reticulocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PCGF5 SLC22A4 CRB1	4.65e-04	183	37	3	5470e5ac3439cfc96acd2202f6b1e386779a6637
ToppCell	droplet-Limb_Muscle-nan-21m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1G GPR174 CYFIP2	4.65e-04	183	37	3	ac70a6ec9270b1bfe089702262d4575a6c42afb4
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1A CYFIP2 SGPP2	4.65e-04	183	37	3	f3728b1a51951c7349f77a3e4d2671ca3a8d2a44
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3\|TCGA-Lung / Sample_Type by Project: Shred V9	TICRR SENP2 FBN2	4.72e-04	184	37	3	ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SCNN1A CASR CYFIP2	4.72e-04	184	37	3	e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SGPP1 FRY SEMA6A	4.79e-04	185	37	3	a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASR CYFIP2 SGPP2	4.87e-04	186	37	3	8eafd4bea692f7ef33de27dd53f9d1fe67deaad8
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_reticulocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PCGF5 SLC22A4 CRB1	4.87e-04	186	37	3	bf8ca7135c05d772aa3f5960b419a13aef3936ae
Drug	Benzethonium chloride [121-54-0]; Up 200; 9uM; HL60; HT_HG-U133A	SGPP1 SCNN1A SLC16A2 SLC22A1 TMEM63A	1.33e-05	195	36	5	2508_UP
Drug	Cefuroxime sodium salt [56238-63-2]; Up 200; 9uM; HL60; HT_HG-U133A	SCNN1A EXTL3 SLC16A2 SLC22A1 CYFIP2	1.43e-05	198	36	5	2526_UP
Drug	Isocorydine (+) [475-67-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A	SFI1 EXTL3 CYFIP2 SLC22A4 TMEM63A	1.43e-05	198	36	5	6843_DN
Drug	Morantel tartrate [26155-31-7]; Up 200; 10.8uM; PC3; HT_HG-U133A	SFI1 FBN2 EXTL3 SLC22A1 CYFIP2	1.47e-05	199	36	5	7250_UP
Disease	chromosome 15q11.2 deletion syndrome (implicated_via_orthology)	CYFIP1 CYFIP2	4.10e-06	3	35	2	DOID:0060393 (implicated_via_orthology)
Disease	butyrylcarnitine measurement	SLC22A1 SLC22A4	3.81e-05	8	35	2	EFO_0020010
Disease	X-11381 measurement	SLC22A1 SLC22A4	4.89e-05	9	35	2	EFO_0021228
Disease	anorexia nervosa	PHIP CRB1 SGPP2	7.92e-05	70	35	3	MONDO_0005351
Disease	intellectual disability (is_implicated_in)	CASR SLC16A2	5.82e-04	30	35	2	DOID:1059 (is_implicated_in)
Disease	retinitis pigmentosa (is_implicated_in)	IMPG1 CRB1	1.09e-03	41	35	2	DOID:10584 (is_implicated_in)
Disease	white matter microstructure measurement	CYFIP1 EXTL3 CRB1 SGPP2	1.14e-03	390	35	4	EFO_0005674

Protein segments in the cluster

Peptide	Gene	Start	Entry
IRYNFRGFRWLQAMI	CASR	61	P41180
FNMRVFRQRTYRIWA	SLC16A2	311	P36021
LWFREFFLELTMGRR	CYFIP1	621	Q7L576
RKRMISLRFLAWYFL	PAN2	1111	Q504Q3
YMTRWRLRGENFRCL	PCGF5	211	Q86SE9
RYLFEIRDWRLMGRL	KIAA0100	1031	Q14667
VDIRWRYMLLIFSLA	KCNJ12	76	Q14500
MYLETRRAIFVFWIF	IMPG1	1	Q17R60
MWRGRNFRVLKYFTR	LCN8	121	Q6JVE9
CISVRRFWFLMYPFR	GPR174	111	Q9BXC1
LVFSIIRRRFWDYGR	TMEM63A	66	O94886
WFREFFLELTMGRRI	CYFIP2	646	Q96F07
NYVSMWFLGIIFRRV	PAPOLG	431	Q9BWT3
LAMRRQGRFLWETYF	EXTL3	506	O43909
YGGLVFMDLLVRRRW	FAM172BP	236	A6NC97
RVALESLYRLLWVYM	FRY	401	Q5TBA9
MGRRRRLCLQLYFLW	FBN2	1	P35556
IMLVYVWSRRNPYVR	DERL2	126	Q9GZP9
QYIRVWLERGRLAML	CRB1	761	P82279
FLMLLRRFRSRYWSP	SCNN1A	581	P37088
PRLRKRTFILMYLWF	SLC22A1	341	O15245
YFIRDWRMLLLALTV	SLC22A4	251	Q9H015
RVIIASWYRTFMGIV	DPY19L2P2	6	Q6ZN68
VDIRWRYMLLIFSLA	KCNJ18	76	B7U540
VARKFLYLWIRMTFG	SFI1	91	A8K8P3
MYRWLVRILGTIFRF	SENP2	1	Q9HC62
LWFRRLYIIFSRYMR	PIGL	231	Q9Y2B2
RRLVVIWVLVMYLGQ	SGPP1	161	Q9BX95
AVVLWLLGYRMRRNA	MRGPRX4	46	Q96LA9
YLSRRLIIIWVLVMY	SGPP2	116	Q8IWX5
RVREVMVARKITFYW	TICRR	196	Q7Z2Z1
RFYRRVSSLMWEVRY	PHIP	1216	Q8WWQ0
FNRPWFLRTMVRYRL	SEMA6A	406	Q9H2E6
GWLMVLYERDCRRRF	UBE3B	596	Q7Z3V4
LLWMNPFVGFRFRRL	ZDHHC7	281	Q9NXF8
GRRTYVTWIALMVFV	AVPR2	201	P30518
IWQTFFRGRYLLLLM	TCIRG1	436	Q13488
IYTIMRWFRRHKVRA	MYO1G	736	B0I1T2
RWAILRAFFRAMVAF	MYO9A	701	B2RTY4