Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionenzyme-substrate adaptor activity

PRAMEF5 PRAMEF9 PRAMEF15 PRAMEF4 RPTOR PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

1.02e-07951679GO:0140767
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

3.65e-07551677GO:0042974
GeneOntologyMolecularFunctionubiquitin-like ligase-substrate adaptor activity

PRAMEF5 PRAMEF9 PRAMEF15 PRAMEF4 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

4.26e-07821678GO:1990756
GeneOntologyMolecularFunction1-phosphatidylinositol-3-kinase activity

PIK3C2A PIK3C2G PIK3CB ATM

1.49e-06111674GO:0016303
GeneOntologyMolecularFunction1-phosphatidylinositol-4-phosphate 3-kinase activity

PIK3C2A PIK3C2G PIK3CB

1.96e-0571673GO:0035005
GeneOntologyMolecularFunctionnuclear receptor binding

PRAMEF5 PRAMEF15 PRAMEF4 PIAS2 GTF2H1 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

2.87e-051871679GO:0016922
GeneOntologyMolecularFunctionglucosyltransferase activity

POGLUT3 ALG10B ALG5 ALG10

3.07e-05221674GO:0046527
GeneOntologyMolecularFunctionphosphatidylinositol kinase activity

PIK3C2A PIK3C2G PIK3CB ATM

6.11e-05261674GO:0052742
GeneOntologyMolecularFunctiondolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity

ALG10B ALG10

6.95e-0521672GO:0106073
GeneOntologyMolecularFunctiondiacyl lipopeptide binding

TLR6 TLR2

6.95e-0521672GO:0042498
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK10 ARFGEF2 BCR DENND3 TIAM2 PLEKHG1 RASGEF1B SPATA13 SOS1

1.46e-042311679GO:0005085
GeneOntologyMolecularFunctionmetalloexopeptidase activity

LVRN NAALAD2 ZMPSTE24 CPB1 ACE

3.01e-04701675GO:0008235
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

ACVR2A DCK BCR EDNRA MAP3K4 POLR3A PIK3C2A PIK3C2G PIK3CB MTOR NANS CLK2 BUB1 POLI DLG1 CARD11 PRKCZ ATM PRKAG2

3.30e-0493816719GO:0016772
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

TBC1D30 DOCK10 ARFGEF2 BCR DENND3 TIAM2 PLEKHG1 NPRL2 NF1 RASGEF1B DEPDC5 SPATA13 SOS1

3.50e-0450716713GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

TBC1D30 DOCK10 ARFGEF2 BCR DENND3 TIAM2 PLEKHG1 NPRL2 NF1 RASGEF1B DEPDC5 SPATA13 SOS1

3.50e-0450716713GO:0030695
GeneOntologyMolecularFunctionlipid kinase activity

PIK3C2A PIK3C2G PIK3CB ATM

3.75e-04411674GO:0001727
GeneOntologyMolecularFunctionhypotaurine monooxygenase activity

FMO1 FMO4

6.84e-0451672GO:0047822
GeneOntologyMolecularFunctionDNA/RNA hybrid binding

POLR3A PRIM2

6.84e-0451672GO:0071667
GeneOntologyMolecularFunctionkinase activity

ACVR2A DCK BCR EDNRA MAP3K4 PIK3C2A PIK3C2G PIK3CB MTOR CLK2 BUB1 DLG1 CARD11 PRKCZ ATM PRKAG2

6.96e-0476416716GO:0016301
GeneOntologyMolecularFunctionN,N-dimethylaniline monooxygenase activity

FMO1 FMO4

1.02e-0361672GO:0004499
GeneOntologyMolecularFunction1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity

PIK3C2A PIK3CB

1.42e-0371672GO:0046934
GeneOntologyMolecularFunctionmetallopeptidase activity

LVRN NAALAD2 ZMPSTE24 ADAM20 ADAM29 CPB1 ACE

1.50e-032001677GO:0008237
GeneOntologyMolecularFunctionneutral L-amino acid:sodium symporter activity

SLC38A2 SLC38A3

1.88e-0381672GO:0005295
GeneOntologyBiologicalProcessoogenesis

PRAMEF5 PRAMEF15 PIWIL2 PRAMEF4 LGR5 EDNRA MARF1 ATM PRAMEF11 PRAMEF6

5.87e-0715616710GO:0048477
GeneOntologyBiologicalProcessoocyte differentiation

PRAMEF5 PRAMEF15 PRAMEF4 LGR5 EDNRA ATM PRAMEF11 PRAMEF6

1.93e-061031678GO:0009994
GeneOntologyBiologicalProcessfemale gamete generation

PRAMEF5 PRAMEF15 PIWIL2 PRAMEF4 LGR5 EDNRA MARF1 ATM PRAMEF11 PRAMEF6 SOS1

2.13e-0622316711GO:0007292
GeneOntologyBiologicalProcessgamete generation

CLGN PRAMEF5 TOPAZ1 ADAM20 NUP210L ACOX1 PRAMEF15 ADAM29 PIWIL2 PRAMEF4 ACVR2A PTCH1 ACE LGR5 EDNRA MTOR MARF1 CATSPERB ATM PRAMEF11 PRAMEF6 HTT SOS1

4.54e-0698216723GO:0007276
GeneOntologyBiologicalProcessoocyte development

PRAMEF5 PRAMEF15 PRAMEF4 EDNRA ATM PRAMEF11 PRAMEF6

1.60e-05991677GO:0048599
GeneOntologyBiologicalProcessdevelopmental process involved in reproduction

CLGN PRAMEF5 TOPAZ1 ADAM20 NUP210L ACOX1 PRAMEF15 ADAM29 PIWIL2 PRAMEF4 ACVR2A PTCH1 ACE LGR5 EDNRA MAP3K4 MTOR MARF1 DLG1 CYP7B1 CATSPERB ATM PRAMEF11 PRAMEF6 HTT

2.08e-05123516725GO:0003006
GeneOntologyBiologicalProcessregulation of autophagy

ZMPSTE24 ATP6V1E2 UFL1 NPRL2 PIK3C2A PIK3CB MTOR RPTOR VPS35 TLR2 DEPDC5 ATM HTT

2.38e-0540016713GO:0010506
GeneOntologyBiologicalProcessdolichol-linked oligosaccharide biosynthetic process

ALG10B ALG9 ALG5 ALG10

2.71e-05221674GO:0006488
GeneOntologyBiologicalProcessphosphatidylinositol-3-phosphate biosynthetic process

PIK3C2A PIK3C2G PIK3CB ATM

2.71e-05221674GO:0036092
GeneOntologyBiologicalProcessmulticellular organismal reproductive process

CLGN PRAMEF5 TOPAZ1 ADAM20 NUP210L ACOX1 PRAMEF15 ADAM29 PIWIL2 PRAMEF4 ACVR2A PTCH1 ACE LGR5 EDNRA TGM4 MTOR MARF1 CATSPERB ATM PRAMEF11 PRAMEF6 HTT SOS1

3.48e-05119416724GO:0048609
GeneOntologyBiologicalProcessdolichol metabolic process

ALG10B ALG9 ALG5 ALG10

3.88e-05241674GO:0019348
GeneOntologyBiologicalProcessgerm cell development

PRAMEF5 NUP210L PRAMEF15 PIWIL2 PRAMEF4 PTCH1 LGR5 EDNRA MTOR MARF1 CATSPERB ATM PRAMEF11 PRAMEF6

3.96e-0548216714GO:0007281
GeneOntologyBiologicalProcesscellular response to nutrient levels

ACVR2A SLC38A2 NPRL2 PIK3C2A MTOR RPTOR DEPDC5 PRKAG2 TTC5 SLC38A3

5.67e-0526216710GO:0031669
GeneOntologyBiologicalProcesshair follicle development

ZMPSTE24 KRT27 LGR5 NF1 CDH3 KRT25 SOS1

6.50e-051231677GO:0001942
GeneOntologyBiologicalProcesstoll-like receptor TLR6:TLR2 signaling pathway

TLR6 TLR2

6.52e-0521672GO:0038124
GeneOntologyBiologicalProcessdetection of diacyl bacterial lipopeptide

TLR6 TLR2

6.52e-0521672GO:0042496
GeneOntologyBiologicalProcessmolting cycle process

ZMPSTE24 KRT27 LGR5 NF1 CDH3 KRT25 SOS1

7.57e-051261677GO:0022404
GeneOntologyBiologicalProcesshair cycle process

ZMPSTE24 KRT27 LGR5 NF1 CDH3 KRT25 SOS1

7.57e-051261677GO:0022405
GeneOntologyBiologicalProcesspolyprenol metabolic process

ALG10B ALG9 ALG5 ALG10

8.41e-05291674GO:0016093
GeneOntologyBiologicalProcessneuromuscular process

MYH3 ZMPSTE24 GRIN2C BCR EDNRA CHRNG MTOR VPS35 CAMTA1

9.39e-052251679GO:0050905
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

PRAMEF5 NUP210L PRAMEF15 PIWIL2 PRAMEF4 PTCH1 LGR5 EDNRA MTOR MARF1 CATSPERB ATM PRAMEF11 PRAMEF6

1.03e-0452716714GO:0022412
GeneOntologyBiologicalProcesscellular response to starvation

SLC38A2 NPRL2 PIK3C2A MTOR RPTOR DEPDC5 TTC5 SLC38A3

1.35e-041851678GO:0009267
GeneOntologyBiologicalProcesssexual reproduction

CLGN PRAMEF5 TOPAZ1 ADAM20 NUP210L ACOX1 PRAMEF15 ADAM29 PIWIL2 PRAMEF4 ACVR2A PTCH1 ACE LGR5 EDNRA MTOR NCAPD2 MARF1 CATSPERB ATM PRAMEF11 PRAMEF6 HTT SOS1

1.50e-04131216724GO:0019953
GeneOntologyBiologicalProcessmeiotic cell cycle phase

TOPAZ1 PIWIL2 NFE2L1

1.78e-04141673GO:0098762
GeneOntologyBiologicalProcessM phase

TOPAZ1 PIWIL2 NFE2L1

1.78e-04141673GO:0000279
GeneOntologyBiologicalProcessdetection of bacterial lipopeptide

TLR6 TLR2

1.94e-0431672GO:0070340
GeneOntologyBiologicalProcessmolting cycle

ZMPSTE24 KRT27 LGR5 NF1 CDH3 KRT25 SOS1

2.24e-041501677GO:0042303
GeneOntologyBiologicalProcesshair cycle

ZMPSTE24 KRT27 LGR5 NF1 CDH3 KRT25 SOS1

2.24e-041501677GO:0042633
GeneOntologyBiologicalProcessorganic hydroxy compound metabolic process

DAB2 ITGAM SERPINA12 EDNRA ALG10B MOXD1 NFE2L1 ALG9 ALG5 VPS35 ALG10 CYP7B1 PRKAG2 CDH3 HTT

2.33e-0464116715GO:1901615
GeneOntologyBiologicalProcessTORC1 signaling

NPRL2 MTOR RPTOR CARD11 DEPDC5 ATM

2.62e-041091676GO:0038202
GeneOntologyBiologicalProcessregulation of ERK1 and ERK2 cascade

PRAMEF5 PRAMEF15 DAB2 PRAMEF4 EDNRA NF1 TLR2 DLG1 PRKCZ PRAMEF11 PRAMEF6

3.12e-0438516711GO:0070372
GeneOntologyBiologicalProcesspachytene

TOPAZ1 PIWIL2

3.87e-0441672GO:0000239
GeneOntologyBiologicalProcesspositive regulation of pentose-phosphate shunt

MTOR RPTOR

3.87e-0441672GO:1905857
GeneOntologyBiologicalProcessdetection of bacterial lipoprotein

TLR6 TLR2

3.87e-0441672GO:0042494
GeneOntologyBiologicalProcessskin epidermis development

ZMPSTE24 KRT27 LGR5 NF1 CDH3 KRT25 SOS1

4.15e-041661677GO:0098773
GeneOntologyBiologicalProcessblastocyst formation

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

4.29e-04781675GO:0001825
GeneOntologyCellularComponentCul2-RING ubiquitin ligase complex

PRAMEF5 PRAMEF9 PRAMEF15 PRAMEF4 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

3.38e-09471678GO:0031462
GeneOntologyCellularComponentcullin-RING ubiquitin ligase complex

PRAMEF5 PRAMEF9 PRAMEF15 PRAMEF4 FBXL3 DEPDC5 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

8.25e-0621216710GO:0031461
GeneOntologyCellularComponentToll-like receptor 2-Toll-like receptor 6 protein complex

TLR6 TLR2

6.34e-0521672GO:0035355
GeneOntologyCellularComponenttransferase complex

PRAMEF5 PRAMEF9 PRAMEF15 PRAMEF4 ACVR2A FBXL3 POLR3A GTF2H1 PIK3C2A PIK3C2G PIK3CB PRIM2 DEPDC5 PRKCZ PRKAG2 MED23 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

8.91e-0596316720GO:1990234
GeneOntologyCellularComponentubiquitin ligase complex

PRAMEF5 PRAMEF9 PRAMEF15 PRAMEF4 FBXL3 DEPDC5 MED23 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

1.29e-0435216711GO:0000151
GeneOntologyCellularComponentextrinsic component of membrane

CDH26 DNAJC6 AP2M1 PIK3C2A PIK3C2G PIK3CB ATM CDH3

5.38e-042301678GO:0019898
GeneOntologyCellularComponentGATOR1 complex

NPRL2 DEPDC5

6.24e-0451672GO:1990130
GeneOntologyCellularComponentcytoplasmic vesicle membrane

ATP13A4 ZMPSTE24 MYO5B SNX24 DAB2 TLR6 PTCH1 ITGAM TLR8 MOXD1 AP2M1 CSF3R VPS35 TLR2 CD53 DLG1 ATP13A3 ATM FRMPD3 CNGA4 SNX22 HTT

7.45e-04130716722GO:0030659
GeneOntologyCellularComponentintracellular protein-containing complex

PRAMEF5 PRAMEF9 PRAMEF15 PRAMEF4 FBXL3 POLR3A GTF2H1 MTOR RPTOR PRIM2 CARD11 DEPDC5 PRKAG2 MED23 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

7.95e-0497216718GO:0140535
GeneOntologyCellularComponentvesicle membrane

ATP13A4 ZMPSTE24 MYO5B SNX24 DAB2 TLR6 PTCH1 ITGAM TLR8 MOXD1 AP2M1 CSF3R VPS35 TLR2 CD53 DLG1 ATP13A3 ATM FRMPD3 CNGA4 SNX22 HTT

8.91e-04132516722GO:0012506
GeneOntologyCellularComponentTORC1 complex

MTOR RPTOR

9.32e-0461672GO:0031931
GeneOntologyCellularComponentextrinsic component of presynaptic endocytic zone membrane

DNAJC6 AP2M1

1.30e-0371672GO:0098894
GeneOntologyCellularComponenttransferase complex, transferring phosphorus-containing groups

ACVR2A POLR3A GTF2H1 PIK3C2A PIK3C2G PIK3CB PRIM2 PRKCZ PRKAG2

1.53e-033351679GO:0061695
GeneOntologyCellularComponentendoplasmic reticulum membrane

ATP13A4 FMO1 CLGN FMO4 ZMPSTE24 SLC27A6 UFL1 BFAR GRIN2C TLR8 ALG10B MOXD1 THADA MTOR NFE2L1 ALG9 ALG5 ALG10 TMC8 DLG1 CYP7B1

1.54e-03129316721GO:0005789
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex

PIK3C2A PIK3C2G PIK3CB

1.57e-03291673GO:0005942
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

ATP13A4 FMO1 CLGN FMO4 ZMPSTE24 SLC27A6 UFL1 BFAR GRIN2C TLR8 ALG10B MOXD1 THADA MTOR NFE2L1 ALG9 ALG5 ALG10 TMC8 DLG1 CYP7B1

1.63e-03129916721GO:0098827
MousePhenoazoospermia

PRAMEF5 TOPAZ1 NUP210L PRAMEF15 PIWIL2 PRAMEF4 ACVR2A FBXO47 PIK3CB FANCI ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

5.68e-0924412715MP:0005159
MousePhenoabnormal spermatogonia proliferation

PRAMEF5 PRAMEF15 PRAMEF4 PIK3CB PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

8.68e-09471278MP:0002685
MousePhenoabsent gametes

PRAMEF5 TOPAZ1 NUP210L PRAMEF15 PIWIL2 PRAMEF4 ACVR2A FBXO47 PIK3CB FANCI ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

1.09e-0825612715MP:0001117
MousePhenoabnormal testis morphology

PRAMEF5 TOPAZ1 NUP210L OR9G4 ACOX1 PRAMEF15 PIWIL2 PRAMEF4 ADGRV1 ACVR2A PTCH1 PIAS2 FBXO47 FBXL3 MAP3K4 NF1 CSF3R PIK3CB FANCI BUB1 DLG1 CARD11 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

1.12e-06108112727MP:0001146
MousePhenoabnormal jejunum morphology

PRAMEF5 PRAMEF15 PRAMEF4 EPCAM PRAMEF11 PRAMEF6

1.73e-06411276MP:0004002
MousePhenoabnormal duodenum morphology

PRAMEF5 PRAMEF15 PRAMEF4 FBXL3 EPCAM PRAMEF11 PRAMEF6

1.75e-06641277MP:0003271
MousePhenoabnormal sperm number

PRAMEF5 TOPAZ1 NUP210L PRAMEF15 PIWIL2 PRAMEF4 ACVR2A PIAS2 FBXO47 MAP3K4 NF1 PIK3CB FANCI BUB1 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

3.43e-0662412719MP:0002673
MousePhenodecreased testis weight

PRAMEF5 TOPAZ1 PRAMEF15 PIWIL2 PRAMEF4 ACVR2A PIAS2 PIK3CB FANCI BUB1 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

6.68e-0637012714MP:0004852
MousePhenoabnormal testis size

PRAMEF5 TOPAZ1 OR9G4 ACOX1 PRAMEF15 PIWIL2 PRAMEF4 ADGRV1 ACVR2A PIAS2 FBXO47 FBXL3 NF1 CSF3R PIK3CB FANCI BUB1 CARD11 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

7.29e-0691512723MP:0004849
MousePhenoincreased male germ cell apoptosis

PRAMEF5 PRAMEF15 PIWIL2 PRAMEF4 FBXO47 FANCI PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

8.56e-0618912710MP:0014052
MousePhenoabnormal male germ cell apoptosis

PRAMEF5 TOPAZ1 PRAMEF15 PIWIL2 PRAMEF4 FBXO47 FANCI PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

1.00e-0523612711MP:0008280
MousePhenoabnormal male reproductive gland morphology

PRAMEF5 KRT27 TOPAZ1 NUP210L OR9G4 ACOX1 PRAMEF15 PIWIL2 PRAMEF4 ADGRV1 ACVR2A PTCH1 PIAS2 FBXO47 FBXL3 MAP3K4 NF1 CSF3R PIK3CB FANCI BUB1 DLG1 CARD11 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

1.04e-05129012728MP:0013325
MousePhenoabnormal sex determination

PRAMEF5 TOPAZ1 ACOX1 PRAMEF15 PIWIL2 PRAMEF4 ADGRV1 ACVR2A DNAJC6 PIAS2 FBXO47 MAP3K4 CSF3R PIK3CB FANCI BUB1 CYP7B1 CARD11 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

1.23e-0594512723MP:0002210
MousePhenoabnormal testis weight

PRAMEF5 TOPAZ1 PRAMEF15 PIWIL2 PRAMEF4 ACVR2A PIAS2 PIK3CB FANCI BUB1 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

1.25e-0539112714MP:0004850
MousePhenoabnormal male germ cell physiology

PRAMEF5 TOPAZ1 PRAMEF15 PIWIL2 PRAMEF4 FBXO47 FANCI PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

1.37e-0524412711MP:0020362
MousePhenodecreased male germ cell number

PRAMEF5 TOPAZ1 NUP210L PRAMEF15 PIWIL2 PRAMEF4 ACVR2A PIAS2 FBXO47 MAP3K4 PIK3CB FANCI BUB1 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

1.87e-0564012718MP:0004901
MousePhenoabnormal germ cell physiology

PRAMEF5 TOPAZ1 PRAMEF15 PIWIL2 PRAMEF4 FBXO47 FANCI PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

3.16e-0526712711MP:0020363
MousePhenoabnormal internal male genitalia morphology

PRAMEF5 KRT27 TOPAZ1 NUP210L OR9G4 ACOX1 PRAMEF15 PIWIL2 PRAMEF4 ADGRV1 ACVR2A PTCH1 PIAS2 FBXO47 FBXL3 MAP3K4 NF1 CSF3R PIK3CB FANCI BUB1 DLG1 CARD11 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

4.20e-05139212728MP:0009205
MousePhenodecreased germ cell number

PRAMEF5 TOPAZ1 NUP210L PRAMEF15 PIWIL2 PRAMEF4 ACVR2A PIAS2 FBXO47 MAP3K4 PIK3CB FANCI BUB1 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

4.77e-0568712718MP:0002209
MousePhenosmall testis

PRAMEF5 TOPAZ1 ACOX1 PRAMEF15 PIWIL2 PRAMEF4 ADGRV1 ACVR2A PIAS2 FBXO47 CSF3R PIK3CB FANCI BUB1 CARD11 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

5.04e-0582312720MP:0001147
MousePhenoabnormal small intestine morphology

PRAMEF5 MYO5B PRAMEF15 PRAMEF4 BCR FBXL3 EPCAM PRAMEF11 PRAMEF6

5.17e-051871279MP:0000496
MousePhenoabnormal male genitalia morphology

PRAMEF5 KRT27 TOPAZ1 NUP210L OR9G4 ACOX1 PRAMEF15 PIWIL2 PRAMEF4 ADGRV1 ACVR2A PTCH1 PIAS2 FBXO47 FBXL3 MAP3K4 NF1 CSF3R PIK3CB FANCI BUB1 DLG1 CARD11 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

5.62e-05141512728MP:0009198
MousePhenoabnormal male reproductive system morphology

PRAMEF5 KRT27 TOPAZ1 NUP210L OR9G4 ACOX1 PRAMEF15 PIWIL2 PRAMEF4 ADGRV1 ACVR2A PTCH1 PIAS2 FBXO47 FBXL3 MAP3K4 NF1 CSF3R PIK3CB FANCI BUB1 DLG1 CARD11 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

5.62e-05141512728MP:0001145
MousePhenoabnormal primary sex determination

PRAMEF5 TOPAZ1 ACOX1 PRAMEF15 PIWIL2 PRAMEF4 ADGRV1 ACVR2A PIAS2 FBXO47 MAP3K4 CSF3R PIK3CB FANCI BUB1 CARD11 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

5.85e-0590112721MP:0002211
MousePhenoabnormal spermatogenesis

PRAMEF5 TOPAZ1 NUP210L ACOX1 PRAMEF15 PIWIL2 PRAMEF4 ACVR2A PTCH1 PIAS2 FBXO47 MAP3K4 NF1 PIK3CB FANCI BUB1 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

6.75e-0591012721MP:0001156
MousePhenoshort mandibular coronoid process

PTCH1 EDNRA

8.19e-0521272MP:0030284
MousePhenoabnormal gametes

PRAMEF5 TOPAZ1 NUP210L PRAMEF15 PIWIL2 PRAMEF4 ACVR2A PIAS2 FBXO47 MAP3K4 NF1 PIK3CB FANCI BUB1 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

8.37e-0578512719MP:0001124
MousePhenoabnormal male germ cell morphology

PRAMEF5 TOPAZ1 NUP210L ACOX1 PRAMEF15 PIWIL2 PRAMEF4 ACVR2A PIAS2 FBXO47 MAP3K4 NF1 PIK3CB FANCI BUB1 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

9.11e-0585912720MP:0006362
MousePhenoabnormal male reproductive system physiology

CLGN PRAMEF5 TOPAZ1 NUP210L ACOX1 PRAMEF15 PIWIL2 PRAMEF4 TLR6 PTCH1 ACE PIAS2 FBXO47 MAP3K4 TGM4 CS NF1 PIK3CB FANCI BUB1 ATP13A3 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

1.32e-04132912726MP:0003698
MousePhenosmall gonad

PRAMEF5 TOPAZ1 ACOX1 PRAMEF15 PIWIL2 PRAMEF4 ADGRV1 ACVR2A PIAS2 FBXO47 CSF3R PIK3CB FANCI BUB1 CARD11 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

1.37e-0488512720MP:0001116
MousePhenosmall second pharyngeal arch

PTCH1 EDNRA MED23

1.96e-04131273MP:0006344
MousePhenoabnormal gametogenesis

PRAMEF5 TOPAZ1 NUP210L ACOX1 PRAMEF15 PIWIL2 PRAMEF4 ACVR2A PTCH1 PIAS2 FBXO47 MAP3K4 NF1 PIK3CB FANCI BUB1 MARF1 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

2.38e-04107012722MP:0001929
MousePhenoabnormal germ cell morphology

PRAMEF5 TOPAZ1 NUP210L ACOX1 PRAMEF15 PIWIL2 PRAMEF4 ACVR2A PIAS2 FBXO47 MAP3K4 NF1 PIK3CB FANCI BUB1 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

3.30e-0494612720MP:0002208
MousePhenoabnormal foam cell morphology

PRAMEF5 TOPAZ1 NUP210L ACOX1 PRAMEF15 PIWIL2 PRAMEF4 ACVR2A PIAS2 FBXO47 MAP3K4 NF1 PIK3CB FANCI BUB1 ATM PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

3.68e-0495412720MP:0009840
MousePhenoabnormal embryo size

ZWILCH DAB2 UFL1 ACVR2A PTCH1 ECSIT ACE ALG10B CHRNG NPRL2 PIK3C2A PIK3CB MTOR NFE2L1 ALG10 DLG1 MED23 EPCAM HTT SOS1

3.78e-0495612720MP:0001697
MousePhenodecreased response to antigen

DCK CARD11 ATM

4.54e-04171273MP:0020001
MousePhenoabnormal programmed cell death

MYH3 PRAMEF5 ZMPSTE24 TOPAZ1 PRAMEF15 DAB2 PIWIL2 PRAMEF4 DCK ITGAM PIAS2 FBXO47 EDNRA SLC38A2 PIK3CB MTOR FANCI TLR2 BUB1 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6 HTT SOS1

4.72e-04136012725MP:0014355
MousePhenoenlarged urinary bladder

PRAMEF5 PRAMEF15 PRAMEF4 POLR3A PRAMEF11 PRAMEF6

6.56e-041161276MP:0011874
DomainPRAME_family

PRAMEF25 PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF6

9.95e-09191636IPR026271
DomainPI3/4_kinase_CS

PIK3C2A PIK3C2G PIK3CB MTOR ATM

1.33e-07151635IPR018936
Domain-

PIK3C2A PIK3C2G PIK3CB MTOR ATM

1.92e-071616351.10.1070.11
DomainPI3Kc

PIK3C2A PIK3C2G PIK3CB MTOR ATM

1.92e-07161635SM00146
DomainPI3_PI4_kinase

PIK3C2A PIK3C2G PIK3CB MTOR ATM

3.72e-07181635PF00454
DomainPI3_4_KINASE_1

PIK3C2A PIK3C2G PIK3CB MTOR ATM

3.72e-07181635PS00915
DomainPI3_4_KINASE_2

PIK3C2A PIK3C2G PIK3CB MTOR ATM

3.72e-07181635PS00916
DomainPI3/4_kinase_cat_dom

PIK3C2A PIK3C2G PIK3CB MTOR ATM

3.72e-07181635IPR000403
DomainPI3_4_KINASE_3

PIK3C2A PIK3C2G PIK3CB MTOR ATM

3.72e-07181635PS50290
DomainARM-type_fold

NBEAL1 ARFGEF2 THADA NF1 PIK3C2A PIK3C2G PIK3CB MTOR RPTOR VPS35 NCAPD2 ATM TARBP1 HTT

1.70e-0633916314IPR016024
DomainPI3K_Ras-bd_dom

PIK3C2A PIK3C2G PIK3CB

2.23e-0571633IPR000341
DomainPI3K_rbd

PIK3C2A PIK3C2G PIK3CB

2.23e-0571633SM00144
DomainPI3K_rbd

PIK3C2A PIK3C2G PIK3CB

2.23e-0571633PF00794
DomainPI3K_RBD

PIK3C2A PIK3C2G PIK3CB

2.23e-0571633PS51546
Domain-

PRAMEF25 PRAMEF5 PRAMEF15 PRAMEF4 TLR6 LGR5 LRCH1 TLR8 FBXL3 TLR2 PRAMEF27 PRAMEF6

2.59e-05321163123.80.10.10
DomainL_dom-like

PRAMEF25 PRAMEF5 PRAMEF15 PRAMEF4 TLR6 LGR5 LRCH1 TLR8 FBXL3 TLR2 PRAMEF27 PRAMEF6

3.20e-0532816312IPR032675
DomainPI3K_C2

PIK3C2A PIK3C2G PIK3CB

3.54e-0581633SM00142
DomainPI3K_C2_dom

PIK3C2A PIK3C2G PIK3CB

3.54e-0581633IPR002420
DomainPI3K_C2

PIK3C2A PIK3C2G PIK3CB

3.54e-0581633PF00792
DomainPI3K_C2

PIK3C2A PIK3C2G PIK3CB

3.54e-0581633PS51547
DomainPI3Ka

PIK3C2A PIK3C2G PIK3CB

5.27e-0591633PF00613
DomainPI3Ka

PIK3C2A PIK3C2G PIK3CB

5.27e-0591633SM00145
Domain-

PIK3C2A PIK3C2G PIK3CB

5.27e-05916331.25.40.70
DomainPI_Kinase

PIK3C2A PIK3C2G PIK3CB

7.49e-05101633IPR015433
DomainPInositide-3_kin_accessory_dom

PIK3C2A PIK3C2G PIK3CB

7.49e-05101633IPR001263
DomainPIK_HELICAL

PIK3C2A PIK3C2G PIK3CB

7.49e-05101633PS51545
DomainAlg10

ALG10B ALG10

7.57e-0521632IPR016900
DomainDIE2_ALG10

ALG10B ALG10

7.57e-0521632PF04922
DomainDH_1

BCR TIAM2 PLEKHG1 SPATA13 SOS1

2.22e-04631635PS00741
DomainRhoGEF

BCR TIAM2 PLEKHG1 SPATA13 SOS1

3.19e-04681635SM00325
DomainGDS_CDC24_CS

BCR TIAM2 PLEKHG1 SOS1

3.62e-04391634IPR001331
DomainRhoGEF

BCR TIAM2 PLEKHG1 SPATA13 SOS1

3.65e-04701635PF00621
DomainDH_2

BCR TIAM2 PLEKHG1 SPATA13 SOS1

3.65e-04701635PS50010
Domain-

BCR TIAM2 PLEKHG1 SPATA13 SOS1

3.90e-047116351.20.900.10
DomainDH-domain

BCR TIAM2 PLEKHG1 SPATA13 SOS1

3.90e-04711635IPR000219
DomainP5-ATPase

ATP13A4 ATP13A3

4.49e-0441632PF12409
DomainPX

SNX24 PIK3C2A PIK3C2G SNX22

5.78e-04441634SM00312
DomainC2_dom

DNAJC6 BCR PIK3C2A PIK3C2G PIK3CB RIMS2 SNRNP200

6.00e-041641637IPR000008
DomainFlavin_mOase

FMO1 FMO4

7.44e-0451632IPR000960
DomainToll-like_receptor

TLR6 TLR2

7.44e-0451632IPR017241
DomainP-type_TPase_V

ATP13A4 ATP13A3

7.44e-0451632IPR006544
DomainDiMe-aniline_mOase

FMO1 FMO4

7.44e-0451632IPR012143
DomainFMO-like

FMO1 FMO4

7.44e-0451632PF00743
DomainFATC

MTOR ATM

7.44e-0451632PF02260
DomainFlavin_mOase-like

FMO1 FMO4

7.44e-0451632IPR020946
DomainTIR

TLR6 TLR8 TLR2

7.73e-04211633SM00255
DomainPX

SNX24 PIK3C2A PIK3C2G SNX22

8.73e-04491634PF00787
DomainTIR

TLR6 TLR8 TLR2

8.90e-04221633PF01582
DomainPX

SNX24 PIK3C2A PIK3C2G SNX22

9.42e-04501634PS50195
Domain-

SNX24 PIK3C2A PIK3C2G SNX22

1.02e-035116343.30.1520.10
Domain-

TLR6 TLR8 TLR2

1.02e-032316333.40.50.10140
DomainPhox

SNX24 PIK3C2A PIK3C2G SNX22

1.09e-03521634IPR001683
DomainFAT

MTOR ATM

1.11e-0361632PS51189
DomainFATC

MTOR ATM

1.11e-0361632PS51190
DomainFAT

MTOR ATM

1.11e-0361632PF02259
DomainPIK-rel_kinase_FAT

MTOR ATM

1.11e-0361632IPR003151
DomainFATC_dom

MTOR ATM

1.11e-0361632IPR003152
DomainPIK_FAT

MTOR ATM

1.11e-0361632IPR014009
DomainFATC

MTOR ATM

1.11e-0361632SM01343
DomainTIR

TLR6 TLR8 TLR2

1.15e-03241633PS50104
DomainTIR_dom

TLR6 TLR8 TLR2

1.30e-03251633IPR000157
DomainPH_dom-like

NBEAL1 FRMPD2 DAB2 DOCK10 BCR TIAM2 PLEKHG1 GTF2H1 FRMPD3 SPATA13 SOS1

1.32e-0342616311IPR011993
DomainHEAT

MTOR RPTOR NCAPD2 HTT

1.64e-03581634IPR000357
DomainZINC_PROTEASE

LVRN ZMPSTE24 ADAM20 ADAM29 ACE

1.68e-03981635PS00142
Domain-

BCR PIK3C2A PIK3C2G PIK3CB RIMS2 SNRNP200

1.92e-0314816362.60.40.150
DomainPDZ

FRMPD2 TIAM2 DLG1 CARD11 FRMPD3 RIMS2

1.92e-031481636SM00228
Domain-

FRMPD2 TIAM2 DLG1 CARD11 FRMPD3 RIMS2

2.05e-0315016362.30.42.10
DomainPDZ

FRMPD2 TIAM2 DLG1 CARD11 FRMPD3 RIMS2

2.12e-031511636PS50106
DomainIg_E-set

POGLUT3 PLXNB2 TGM4 CAMTA1 SNRNP200

2.19e-031041635IPR014756
DomainPDZ

FRMPD2 TIAM2 DLG1 CARD11 FRMPD3 RIMS2

2.19e-031521636IPR001478
DomainARM-like

DOCK10 ARFGEF2 NF1 MTOR RPTOR NCAPD2 TARBP1 HTT

2.60e-032701638IPR011989
DomainSSD

PTCH1 DISP2

5.54e-03131632IPR000731
DomainSSD

PTCH1 DISP2

5.54e-03131632PS50156
DomainUbiquitin-rel_dom

FRMPD2 SACS PIK3C2A PIK3C2G PIK3CB FRMPD3

5.59e-031841636IPR029071
DomainDynein_heavy_chain_D4_dom

DNAH12 DNAH6

6.43e-03141632IPR024317
DomainDynein_heavy_dom-2

DNAH12 DNAH6

6.43e-03141632IPR013602
DomainDHC_N2

DNAH12 DNAH6

6.43e-03141632PF08393
DomainATPase_dyneun-rel_AAA

DNAH12 DNAH6

6.43e-03141632IPR011704
DomainRas_G-nucl-exch_fac_CS

RASGEF1B SOS1

6.43e-03141632IPR019804
DomainAAA_8

DNAH12 DNAH6

6.43e-03141632PF12780
DomainAAA_5

DNAH12 DNAH6

6.43e-03141632PF07728
DomainDHC_fam

DNAH12 DNAH6

7.38e-03151632IPR026983
DomainDynein_heavy

DNAH12 DNAH6

7.38e-03151632PF03028
DomainDynein_heavy_dom

DNAH12 DNAH6

7.38e-03151632IPR004273
Domain-

FRMPD2 DAB2 DOCK10 BCR TIAM2 PLEKHG1 GTF2H1 SPATA13 SOS1

7.48e-0339116392.30.29.30
DomainPDZ

FRMPD2 TIAM2 DLG1 FRMPD3 RIMS2

7.95e-031411635PF00595
DomainKinase-like_dom

ACVR2A MAP3K4 PIK3C2A PIK3C2G PIK3CB MTOR CLK2 BUB1 PRKCZ ATM SOS1

8.12e-0354216311IPR011009
DomainDisintegrin_CS

ADAM20 ADAM29

8.38e-03161632IPR018358
DomainHEAT

RPTOR NCAPD2 HTT

8.47e-03481633PF02985
PathwayWP_SYNAPTIC_SIGNALING_ASSOCIATED_WITH_AUTISM_SPECTRUM_DISORDER

GRIN2C NF1 PIK3CB MTOR RPTOR PRKAG2

4.12e-06501216M39822
PathwayKEGG_MEDICUS_REFERENCE_GATOR1_MTORC1_SIGNALING_PATHWAY

NPRL2 MTOR RPTOR DEPDC5

4.84e-06141214M47918
PathwayWP_ANGIOPOIETINLIKE_PROTEIN_8_REGULATORY_PATHWAY

MAP3K4 PIK3C2A PIK3C2G PIK3CB MTOR RPTOR PRKAG2 SOS1

1.77e-051321218M39338
PathwayREACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN

ALG10B ST3GAL5 NANS ALG9 ALG5 ALG10

5.89e-05791216M897
PathwayWP_EFFECT_OF_OMEGA3_PUFA_ON_HUNTINGTONS_DISEASE_PATHWAYS

PIK3C2A PIK3C2G PIK3CB MTOR RPTOR PRKAG2 HTT

7.30e-051191217M48309
PathwayWP_GLIOBLASTOMA_SIGNALING

NF1 PIK3C2A PIK3C2G PIK3CB PRKCZ ATM

7.77e-05831216M39637
PathwayREACTOME_AMINO_ACIDS_REGULATE_MTORC1

ATP6V1E2 NPRL2 MTOR RPTOR DEPDC5

1.06e-04551215M29825
PathwayREACTOME_AMINO_ACIDS_REGULATE_MTORC1

ATP6V1E2 NPRL2 MTOR RPTOR DEPDC5

1.15e-04561215MM15667
Pubmed

Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

8.68e-1222168731729367
Pubmed

MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

2.42e-1125168737451217
Pubmed

Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

5.88e-1128168725089626
Pubmed

Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

3.25e-1035168719389355
Pubmed

Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11 PRAMEF6

4.26e-1020168626694250
Pubmed

Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

1.46e-0817168523565261
Pubmed

Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

1.46e-0817168537781892
Pubmed

Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

2.02e-0818168539181896
Pubmed

Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

2.02e-0818168529731491
Pubmed

Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

2.02e-0818168514675769
Pubmed

The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

2.02e-0818168523894331
Pubmed

Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

2.02e-0818168512890732
Pubmed

Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

2.73e-0819168528604677
Pubmed

Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

3.62e-0820168521425410
Pubmed

Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

3.62e-0820168516580637
Pubmed

Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

7.77e-0823168519480014
Pubmed

Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

1.22e-0725168512620990
Pubmed

Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

1.50e-0726168518500982
Pubmed

Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

3.20e-0730168538786026
Pubmed

Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1.

NPRL2 MTOR RPTOR DEPDC5

3.63e-0713168426051179
Pubmed

An abundance of X-linked genes expressed in spermatogonia.

PRAMEF5 PRAMEF15 PIWIL2 PRAMEF4 PRAMEF11 PRAMEF6

4.23e-0759168611279525
Pubmed

mTOR disruption causes intestinal epithelial cell defects and intestinal atrophy postinjury in mice.

LGR5 MTOR RPTOR

4.41e-074168326631481
Pubmed

LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

4.49e-0732168537889087
Pubmed

Polymorphisms of innate pattern recognition receptors, response to interferon-beta and development of neutralizing antibodies in multiple sclerosis patients.

TLR6 TLR8 IFIH1 TLR2

5.06e-0714168420595247
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

PRAMEF5 TM9SF4 PRAMEF15 UFL1 PRAMEF4 ANO10 PLXNB2 PIAS2 FBXO47 WDR3 ANKRD13A SLC38A2 PLEKHG1 NF1 PIK3CB MTOR FANCI PRKCZ MED23 PRAMEF11 PRAMEF6

6.70e-0712421682130973865
Pubmed

mTORC2 phosphorylates protein kinase Cζ to regulate its stability and activity.

MTOR RPTOR PRKCZ

1.10e-065168324375676
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

ARMT1 ZWILCH PRAMEF5 ZMPSTE24 DHX38 PRAMEF15 PRAMEF4 ACVR2A PTCH1 TIAM2 TGM4 SLC38A2 NFE2L1 DLG1 PRKCZ CKAP2 CAMTA1 PRAMEF11 PRAMEF6

1.40e-0610841681911544199
Pubmed

Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.

AP2M1 PIK3CB RPTOR SOS1

1.92e-0619168431959764
Pubmed

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.

NPRL2 MTOR RPTOR DEPDC5

2.40e-0620168428199306
Pubmed

Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

2.89e-0646168517287250
Pubmed

Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-alpha, and -epsilon and -zeta isoforms in PC12 cells.

PIK3C2A PIK3C2G PIK3CB PRKCZ

2.95e-062116849446795
Pubmed

HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes.

PIK3C2A PIK3C2G PIK3CB PRKCZ

3.59e-0622168411154208
Pubmed

A molecular-properties-based approach to understanding PDZ domain proteins and PDZ ligands.

BCR DLG1 CARD11

3.82e-067168316825666
Pubmed

Defining the membrane proteome of NK cells.

ZMPSTE24 ACOX1 DHX38 DOCK10 ARFGEF2 ANO10 BCR POLR3A EFTUD2 NF1 PIK3C2A MTOR FANCI ALG9 ALG5 BUB1 NCAPD2 MARF1 ATP13A3

4.14e-0611681681919946888
Pubmed

Phosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lamblia.

PIK3C2A PIK3C2G PIK3CB TLR2

4.33e-0623168419047410
Pubmed

DUX is a non-essential synchronizer of zygotic genome activation.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

4.40e-0650168531806660
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

MYH3 BSPRY UFL1 MRPL45 DNAJC6 TIAM2 WDR3 SRPX2 NF1 MTOR ALG5 BUB1 CYP7B1 DEPDC5 ATP13A3 RIMS2 EPCAM SERPIND1 SLC38A3 SPATA13

4.81e-0612931682015342556
Pubmed

Amino acid-dependent NPRL2 interaction with Raptor determines mTOR Complex 1 activation.

NPRL2 RPTOR DEPDC5

6.09e-068168326582740
Pubmed

Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response.

TLR6 TLR8 TLR2

6.09e-068168320100933
Pubmed

Signalling crosstalk in FGF2-mediated protection of endothelial cells from HIV-gp120.

PIK3C2A PIK3C2G PIK3CB PRKCZ

6.14e-0625168415689238
Pubmed

TLR5 Supports Development of Placental Labyrinthine Zone in Mice.

TLR6 TLR8 MTOR TLR2

7.23e-0626168434395439
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ARFGEF2 PTCH1 BCR PLXNB2 TIAM2 PLEKHG1 THADA MTOR FANCI RPTOR NCAPD2 PCNX1 DISP2 DEPDC5 ZNF839 TTC5 HTT SPATA13

7.40e-0611051681835748872
Pubmed

5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.

NF1 MTOR RPTOR ATM

8.45e-0627168423027611
Pubmed

Regulation of angiogenesis, mural cell recruitment and adventitial macrophage behavior by Toll-like receptors.

TLR6 TLR8 TLR2

9.10e-069168324091496
Pubmed

Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival.

NF1 MTOR RPTOR

9.10e-069168327340174
Pubmed

The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation.

NPRL2 MTOR DEPDC5

9.10e-069168325936802
Pubmed

ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation.

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

9.23e-0658168531598710
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

U2SURP DHX38 DOCK10 URB2 DCK POLR3A EFTUD2 WDR3 GTF2H1 AP2M1 CS NF1 PIK3C2A NANS FANCI RPTOR PRIM2 VPS35 NCAPD2 SNRNP200

9.36e-0613531682029467282
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UFL1 ADGRV1 BCR LRCH1 TIAM2 SLC38A2 RPTOR NCAPD2 PCNX1 DEPDC5 MED23 RIMS2

1.12e-055291681214621295
Pubmed

The DNA sequence and biological annotation of human chromosome 1.

FMO1 PRAMEF25 PRAMEF5 FMO4 PRAMEF9 ZMPSTE24 NUP210L OR2G2 PRAMEF4 DNAJC6 MTOR CD53 PRKCZ CAMTA1 TARBP1 PRAMEF11 PRAMEF6

1.15e-0510311681716710414
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

ARFGEF2 NF1 FANCI ATM TARBP1 HTT

1.19e-05104168631240132
Pubmed

Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells.

PIK3C2A PIK3C2G PIK3CB

1.30e-051016838798481
Pubmed

Polymorphisms in innate immunity genes associated with development of bronchiolitis obliterans after lung transplantation.

TLR6 TLR8 TLR2

1.30e-0510168320227302
Pubmed

Expression of HIV-1 nef decreases basal phosphatidyl-inositol 3-kinase activity.

PIK3C2A PIK3C2G PIK3CB

1.30e-051016839247029
Pubmed

The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1.

PIK3C2A PIK3C2G PIK3CB

1.30e-051016838636073
Pubmed

[Expression of toll-like receptors in human epidermal keratinocytes].

TLR6 TLR8 TLR2

1.30e-0510168318686608
Pubmed

Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome.

TLR6 ITGAM TLR2

1.30e-0510168318180310
Pubmed

Toll-like receptors.

TLR6 TLR8 TLR2

1.30e-0510168311782555
Pubmed

A family of human receptors structurally related to Drosophila Toll.

TLR6 TLR8 TLR2

1.30e-051016839435236
Pubmed

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.

ECSIT BCR PIAS2 MAP3K4 PIK3CB MTOR BUB1 DLG1 PRKCZ SOS1

1.43e-053711681025241761
Pubmed

Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells.

PIK3C2A PIK3C2G PIK3CB

1.78e-0511168312584329
Pubmed

Ligands of CD4 inhibit the association of phospholipase Cgamma1 with phosphoinositide 3 kinase in T cells: regulation of this association by the phosphoinositide 3 kinase activity.

PIK3C2A PIK3C2G PIK3CB

1.78e-051116839808187
Pubmed

HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells.

PIK3C2A PIK3C2G PIK3CB

1.78e-051116839708406
Pubmed

A noncanonical PWI domain in the N-terminal helicase-associated region of the spliceosomal Brr2 protein.

DHX38 EFTUD2 SNRNP200

1.78e-0511168325849387
Pubmed

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.

MTOR RPTOR ATM

1.78e-0511168320427287
Pubmed

HIV-1 gp120-induced TNF-{alpha} production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen-activated protein (MAP) kinase pathways.

PIK3C2A PIK3C2G PIK3CB

1.78e-0511168316081599
Pubmed

Toll-like receptors.

TLR6 TLR8 TLR2

1.78e-0511168318394314
Pubmed

HIV-Nef enhances interleukin-2 production and phosphatidylinositol 3-kinase activity in a human T cell line.

PIK3C2A PIK3C2G PIK3CB

1.78e-0511168310985305
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

U2SURP DHX38 UFL1 URB2 POLR3A EFTUD2 WDR3 SLC38A2 THADA AP2M1 CS NF1 MTOR FANCI RPTOR VPS35 NCAPD2 ATM MED23 SNRNP200

1.97e-0514251682030948266
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

CLGN DAB2 UFL1 MRPL45 ECSIT POLR3A EFTUD2 WDR3 ANKRD13A THADA AP2M1 PIK3C2A MTOR FANCI ALG5 VPS35 NCAPD2 ATP13A3 ATM SNRNP200

2.29e-0514401682030833792
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

SP100 ZMPSTE24 TM9SF4 URB2 ANO10 PLXNB2 PIAS2 LRCH1 EFTUD2 WDR3 FANCI RPTOR ALG9 ALG5 VPS35 NCAPD2 MED23 SNRNP200

2.30e-0512031681829180619
Pubmed

Assembly of the TLR2/6 transmembrane domains is essential for activation and is a target for prevention of sepsis.

TLR6 TLR2

2.32e-052168223677476
Pubmed

Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activation.

MTOR PRKCZ

2.32e-052168221911744
Pubmed

Live Faecalibacterium prausnitzii induces greater TLR2 and TLR2/6 activation than the dead bacterium in an apical anaerobic co-culture system.

TLR6 TLR2

2.32e-052168229112296
Pubmed

Toll-like receptor 2/6 agonist macrophage-activating lipopeptide-2 promotes reendothelialization and inhibits neointima formation after vascular injury.

TLR6 TLR2

2.32e-052168223868938
Pubmed

MDA5 is SUMOylated by PIAS2β in the upregulation of type I interferon signaling.

PIAS2 IFIH1

2.32e-052168221156324
Pubmed

Mycobacterium tuberculosis lipoprotein-induced association of TLR2 with protein kinase C zeta in lipid rafts contributes to reactive oxygen species-dependent inflammatory signalling in macrophages.

TLR2 PRKCZ

2.32e-052168218503635
Pubmed

Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning.

MTOR RPTOR

2.32e-052168227018708
Pubmed

Co-upregulation of Toll-like receptors 2 and 6 on peripheral blood cells in patients with obstructive sleep apnea.

TLR6 TLR2

2.32e-052168225604476
Pubmed

Differential expression of toll-like receptor 6 on granulocytes and monocytes implicates the role of microorganisms in Behcet's disease etiopathogenesis.

TLR6 TLR2

2.32e-052168217934735
Pubmed

Anthrax toxin evades Toll-like receptor recognition, whereas its cell wall components trigger activation via TLR2/6 heterodimers.

TLR6 TLR2

2.32e-052168217651447
Pubmed

NF1 patient missense variants predict a role for ATM in modifying neurofibroma initiation.

NF1 ATM

2.32e-052168231664505
Pubmed

Lipid droplet formation in leprosy: Toll-like receptor-regulated organelles involved in eicosanoid formation and Mycobacterium leprae pathogenesis.

TLR6 TLR2

2.32e-052168219952355
Pubmed

Clostridioides difficile Binary Toxin Is Recognized by the Toll-Like Receptor 2/6 Heterodimer to Induce a Nuclear Factor-κB Response.

TLR6 TLR2

2.32e-052168233011801
Pubmed

Role of protein kinase Czeta and its adaptor protein p62 in voltage-gated potassium channel modulation in pulmonary arteries.

GTF2H1 PRKCZ

2.32e-052168217699685
Pubmed

Testosterone persistently dysregulates hepatic expression of Tlr6 and Tlr8 induced by Plasmodium chabaudi malaria.

TLR6 TLR8

2.32e-052168225056943
Pubmed

Hyperactivation of mTOR critically regulates abnormal osteoclastogenesis in neurofibromatosis Type 1.

NF1 MTOR

2.32e-052168221748792
Pubmed

DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting.

MTOR DEPDC5

2.32e-052168236044864
Pubmed

Selective passage through the uterotubal junction of sperm from a mixed population produced by chimeras of calmegin-knockout and wild-type male mice.

CLGN ACE

2.32e-052168215151931
Pubmed

Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking.

MTOR RPTOR

2.32e-052168217301289
Pubmed

Transmembrane oligomeric form of Vibrio cholerae cytolysin triggers TLR2/TLR6-dependent proinflammatory responses in monocytes and macrophages.

TLR6 TLR2

2.32e-052168225431887
Pubmed

Activation of TLR2 and TLR6 by Dengue NS1 Protein and Its Implications in the Immunopathogenesis of Dengue Virus Infection.

TLR6 TLR2

2.32e-052168226226614
Pubmed

Hepatic peroxisomal β-oxidation suppresses lipophagy via RPTOR acetylation and MTOR activation.

MTOR RPTOR

2.32e-052168232687428
Pubmed

Genetic predisposition of variants in TLR2 and its co-receptors to severe malaria in Odisha, India.

TLR6 TLR2

2.32e-052168226621243
Pubmed

mTOR inhibition prevents rapid-onset of carcinogen-induced malignancies in a novel inducible HPV-16 E6/E7 mouse model.

LGR5 MTOR

2.32e-052168227538837
Pubmed

PF-04691502, a dual PI3K/mTOR inhibitor has potent pre-clinical activity by inducing apoptosis and G1 cell cycle arrest in aggressive B-cell non-Hodgkin lymphomas.

PIK3CB MTOR

2.32e-052168226549638
Pubmed

Local activation of uterine Toll-like receptor 2 and 2/6 decreases embryo implantation and affects uterine receptivity in mice.

TLR6 TLR2

2.32e-052168224621922
Pubmed

Toll-like receptors 2 and 6 mediate apoptosis and inflammation in ischemic skeletal myotubes.

TLR6 TLR2

2.32e-052168231084431
Pubmed

The mTORC1 component RPTOR is required for maintenance of the foundational spermatogonial stem cell pool in mice†.

MTOR RPTOR

2.32e-052168230202948
Pubmed

Bacillus subtilis programs the differentiation of intestinal secretory lineages to inhibit Salmonella infection.

LGR5 TLR2

2.32e-052168236170821
InteractionGPR17 interactions

ZWILCH ARFGEF2 UFL1 MAP3K4 THADA SACS MTOR ALG10 NCAPD2 ATP13A3 ATM MED23 TARBP1 HTT

5.73e-0828315914int:GPR17
InteractionOPALIN interactions

SLC27A6 ARFGEF2 URB2 ACVR2A THADA NF1 MTOR FANCI RPTOR ATP13A3 ATM TARBP1

1.06e-0720915912int:OPALIN
InteractionC3orf18 interactions

ARFGEF2 UFL1 THADA NF1 SACS MTOR EXOC6B TARBP1 SOS1

3.25e-071151599int:C3orf18
InteractionPRAMEF4 interactions

PRAMEF5 PRAMEF9 PRAMEF4

4.82e-0731593int:PRAMEF4
InteractionGPR182 interactions

ZWILCH TM9SF4 ARFGEF2 UFL1 URB2 DCK THADA PIK3C2A MTOR FANCI NCAPD2 ATP13A3 ATM MED23 TARBP1 HTT

6.67e-0745515916int:GPR182
InteractionSLAMF1 interactions

SLC27A6 ARFGEF2 URB2 ADGRV1 ANKRD13A MOXD1 NF1 FANCI

6.78e-061251598int:SLAMF1
InteractionFAM234A interactions

ZWILCH ARFGEF2 THADA NF1 MTOR EXOC6B ATM TARBP1

7.19e-061261598int:FAM234A
InteractionGYPA interactions

ZWILCH UFL1 URB2 THADA NF1 MTOR NCAPD2 EXOC6B TARBP1

1.02e-051741599int:GYPA
InteractionPRAMEF5 interactions

PRAMEF5 PRAMEF15 PRAMEF4

2.62e-0581593int:PRAMEF5
InteractionUNC93B1 interactions

CLGN UFL1 ECSIT TLR8 EDNRA ANKRD13A THADA MTOR FANCI VPS35 NCAPD2 ATP13A3 ATM

2.78e-0541715913int:UNC93B1
InteractionARRDC4 interactions

PLXNB2 ANKRD13A IFIH1 NF1 FANCI ATM

5.02e-05831596int:ARRDC4
InteractionPRAMEF15 interactions

PRAMEF5 PRAMEF15

6.19e-0521592int:PRAMEF15
InteractionSLC7A6OS interactions

DHX38 POLR3A EFTUD2 SNRNP200

6.59e-05281594int:SLC7A6OS
InteractionHTR6 interactions

AP2M1 NF1 MTOR RPTOR ATM

9.39e-05581595int:HTR6
Cytoband1p36.21

PRAMEF25 PRAMEF5 PRAMEF9 PRAMEF15 PRAMEF4 PRAMEF26 PRAMEF11 PRAMEF6

8.87e-116316881p36.21
CytobandEnsembl 112 genes in cytogenetic band chr1p36

PRAMEF25 PRAMEF5 PRAMEF9 PRAMEF15 PRAMEF4 MTOR PRKCZ CAMTA1 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

8.90e-0668116812chr1p36
Cytoband2p21

ATP6V1E2 THADA EPCAM SOS1

7.67e-056116842p21
Cytoband6q25.1

ARMT1 UST PLEKHG1

3.70e-043816836q25.1
GeneFamilyPRAME family

PRAMEF25 PRAMEF5 PRAMEF9 PRAMEF15 PRAMEF4 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

3.23e-14241259686
GeneFamilyPhosphatidylinositol 3-kinase subunits

PIK3C2A PIK3C2G PIK3CB

1.76e-0581253831
GeneFamilyCD molecules|Toll like receptors

TLR6 TLR8 TLR2

3.74e-05101253948
GeneFamilyAlpha-1,2-glucosyltransferases

ALG10B ALG10

4.74e-0521252448
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

BCR TIAM2 PLEKHG1 SPATA13 SOS1

9.30e-05661255722
GeneFamilyMTOR complex 1|MTOR complex 2

MTOR RPTOR

2.82e-04412521332
GeneFamilyParkinson disease associated genes|ATPase orphan transporters

ATP13A4 ATP13A3

4.68e-04512521213
GeneFamilyPDZ domain containing

FRMPD2 TIAM2 DLG1 CARD11 FRMPD3 RIMS2

6.60e-0415212561220
GeneFamilyX-linked mental retardation|RNA helicases

IFIH1 SNRNP200

2.50e-031112521168
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DOCK10 BCR TIAM2 PLEKHG1 SPATA13 SOS1

3.11e-032061256682
CoexpressionBYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS

MYH3 NAALAD2 PRAMEF5 PRAMEF15 PRAMEF4 NF1 NANS SERPIND1 PRAMEF11 PRAMEF6

2.39e-0718016610MM612
CoexpressionINGRAM_SHH_TARGETS_UP

FMO1 PRAMEF5 PRAMEF15 PRAMEF4 PTCH1 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

7.10e-071561669MM550
CoexpressionKOHOUTEK_CCNT2_TARGETS

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF6

8.44e-07811667MM938
CoexpressionKINNEY_DNMT1_METHYLATION_TARGETS

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

2.30e-06341665MM955
CoexpressionYAMAZAKI_TCEB3_TARGETS_DN

PRAMEF5 PRAMEF15 PRAMEF4 PTCH1 PRAMEF26 EPCAM CDH3 PRAMEF27 PRAMEF11 PRAMEF6

2.42e-0623216610MM1019
CoexpressionMARTINEZ_RESPONSE_TO_TRABECTEDIN_DN

ARFGEF2 DCK FBXL3 TIAM2 MAP3K4 GTF2H1 SACS PRIM2 BUB1 TARBP1

9.86e-0627216610M15123
CoexpressionPARENT_MTOR_SIGNALING_UP

SAMD9 TM9SF4 ACOX1 PIWIL2 ANO10 NPRL2 THADA MTOR CLK2 PRIM2 CD53 DEPDC5 PRKAG2 SERPIND1

1.63e-0556716614M16909
CoexpressionZHENG_BOUND_BY_FOXP3

SP100 TBC1D30 DOCK10 TLR6 PIAS2 LRCH1 UST TLR8 THADA POLI EXOC6B CD53 TTC5

1.85e-0549816613M1741
CoexpressionZHENG_BOUND_BY_FOXP3

SP100 TBC1D30 DOCK10 TLR6 PIAS2 LRCH1 UST TLR8 THADA POLI EXOC6B CD53 TTC5

2.23e-0550716613MM1030
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3_UNMETHYLATED

PRAMEF5 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6

3.08e-05571665MM1262
CoexpressionDESCARTES_ORGANOGENESIS_SCHWANN_CELL_PRECURSOR

PRAMEF5 PRAMEF15 PRAMEF4 MOXD1 PRAMEF11 PRAMEF6

3.83e-05981666MM3656
CoexpressionGSE13411_PLASMA_CELL_VS_MEMORY_BCELL_DN

SP100 DOCK10 DCK UST MARF1 CD53 PRKCZ TARBP1

3.87e-051971668M3255
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED

PRAMEF5 KRT27 PRAMEF15 PRAMEF4 PCDHB18P TMC8 CNGA4 PRAMEF11 PRAMEF6

4.56e-052611669MM1277
CoexpressionAtlasdev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_500

ZWILCH PIWIL2 URB2 PIK3CB BUB1 POLI CKAP2 RIMS2 EPCAM

8.18e-071421519gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k3_500
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_500

ZWILCH ARFGEF2 PIWIL2 FANCI BUB1 PRKCZ CKAP2 RIMS2 EPCAM

1.45e-061521519gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_500
CoexpressionAtlasdev gonad_e11.5_F_PrimGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_500

ZWILCH PIWIL2 URB2 PIK3CB BUB1 POLI CKAP2 RIMS2 EPCAM

2.71e-061641519gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_k2_500
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000

ZWILCH PIWIL2 URB2 DCK FBXO47 EFTUD2 WDR3 PIK3CB NANS FANCI BUB1 POLI PRKCZ ATM CKAP2 RIMS2 EPCAM CDH3

1.47e-0579515118gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000

ZWILCH PIWIL2 MRPL45 URB2 FBXO47 EFTUD2 WDR3 THADA PIK3CB MTOR BUB1 POLI ATM CKAP2 MED23 RIMS2 EPCAM CDH3

1.88e-0581015118gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_500

ZWILCH PIWIL2 URB2 FBXO47 PIK3CB FANCI BUB1 POLI ATM CKAP2 RIMS2 EPCAM

2.18e-0538715112gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_500
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

ZWILCH ARFGEF2 PIWIL2 URB2 DCK FBXO47 MTOR FANCI PRIM2 BUB1 POLI PRKCZ ATM CKAP2 PRKAG2 RIMS2 EPCAM HTT

2.21e-0582015118gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000

ZWILCH ARFGEF2 PIWIL2 URB2 FBXO47 EFTUD2 THADA PIK3CB MTOR FANCI PRIM2 BUB1 POLI PRKCZ ATM CKAP2 RIMS2 EPCAM

2.29e-0582215118gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000

ZWILCH PIWIL2 EFTUD2 WDR3 THADA MTOR BUB1 POLI ATM CKAP2 MED23

2.73e-0533315111gudmap_dev gonad_e13.5_M_GermCell_Oct_k1_1000
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_500

ZWILCH PIWIL2 URB2 FBXO47 PIK3CB FANCI BUB1 POLI ATM CKAP2 RIMS2 EPCAM

3.49e-0540615112gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_500
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000

ZWILCH ARFGEF2 PIWIL2 DCK MTOR FANCI PRIM2 BUB1 PRKCZ ATM CKAP2

5.67e-0536115111gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_1000
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#4_top-relative-expression-ranked_500

PIWIL2 URB2 POLI CKAP2 RIMS2 EPCAM

8.51e-051011516gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k4_500
CoexpressionAtlasDevelopingKidney_e15.5_Podocyte cells_emap-27915_top-relative-expression-ranked_1000

ARMT1 ZWILCH NAALAD2 MYO5B DAB2 DOCK10 ARFGEF2 PLEKHG1 KCNC2 PRIM2 TLR2 CD53 CYP7B1 ATP13A3 CAMTA1 RIMS2 SPATA13

9.72e-0583615117gudmap_developingKidney_e15.5_Podocyte cells_1000
CoexpressionAtlasMyeloid Cells, MF.169+11chi.SLN, CD11b+ CD169+ CD11chigh, Lymph Node, avg-2

DAB2 ACE ITGAM PLXNB2 TLR8 ST3GAL5 PIK3CB TLR2 RASGEF1B CYP7B1 SNX22

1.01e-0438515111GSM854315_500
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500

ZWILCH ARFGEF2 PIWIL2 FBXO47 FANCI BUB1 PRKCZ ATM CKAP2 RIMS2 EPCAM

1.01e-0438515111gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#2_top-relative-expression-ranked_1000

ZWILCH PIWIL2 DCK EFTUD2 FANCI BUB1 PRKCZ ATM CKAP2

1.25e-042661519gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k2_1000
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_500

ZWILCH PIWIL2 URB2 FBXO47 PIK3CB BUB1 POLI ATM CKAP2 RIMS2 EPCAM

1.29e-0439615111gudmap_dev gonad_e13.5_M_GermCell_Oct_500
CoexpressionAtlasdev gonad_e11.5_M_PrimGermCell_Oct_top-relative-expression-ranked_1000

ZWILCH PIWIL2 URB2 DCK EFTUD2 PIK3CB NANS FANCI BUB1 NCAPD2 POLI ATM CKAP2 RIMS2 EPCAM CDH3

1.45e-0478115116gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_1000
CoexpressionAtlasdev gonad_e11.5_F_PrimGermCell_Oct_top-relative-expression-ranked_1000

ZWILCH ARFGEF2 PIWIL2 URB2 PIK3CB NANS FANCI BUB1 NCAPD2 POLI PRKCZ ATM CKAP2 RIMS2 EPCAM CDH3

1.87e-0479915116gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_1000
CoexpressionAtlasPP_RBC_top-relative-expression-ranked_2500_k-means-cluster#4

MYH3 SAMD9 BSPRY DOCK10 CPB1 TLR6 DCK IFIH1 CSF3R FANCI NCAPD2 TMC8 CD53 ZNF839 TARBP1

2.21e-0472815115PP_RBC_2500_K4
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#4_top-relative-expression-ranked_1000

PIWIL2 URB2 EFTUD2 THADA MTOR POLI RIMS2 EPCAM

3.57e-042431518gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k4_1000
ToppCellPCW_10-12-Epithelial|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 MYO5B BSPRY ADGRV1 ST3GAL5 PIK3C2G CATSPERB PRKCZ EPCAM CDH3

4.05e-09196168109bfb31ff3e4f2c0a9405c418c86bfec5dbca23e2
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 MYO5B ADGRV1 ST3GAL5 PIK3C2G TLR2 PRKCZ EPCAM CDH3

3.90e-081861689bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MYO5B BSPRY ADGRV1 ST3GAL5 PIK3C2G CATSPERB PRKCZ EPCAM CDH3

6.12e-0819616890a34a0009f479384f1994c6f977f942699a132c8
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Monophasic_Synovial_Sarcoma-5|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

PRAMEF5 PRAMEF9 PRAMEF15 OR4E2 PRAMEF4 PRAMEF11 PRAMEF6

6.46e-089316873e05ea0f8f4a7cdb78a596f47d563dc3c94d4d8e
ToppCellTCGA-Stomach-Primary_Tumor|TCGA-Stomach / Sample_Type by Project: Shred V9

ZWILCH URB2 EFTUD2 FANCI PRIM2 BUB1 ATP13A3 CKAP2 EPCAM

6.97e-08199168938f1f612b29feb868322999ceeda78e52447ec4f
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma|TCGA-Stomach / Sample_Type by Project: Shred V9

ZWILCH URB2 EFTUD2 FANCI PRIM2 BUB1 ATP13A3 CKAP2 EPCAM

6.97e-081991689b10698aee2e6c17bc559eb4f723024141f914b90
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_cell-B_naive|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SP100 DOCK10 DCK ITGAM PLEKHG1 TMC8 CD53 CARD11 SNX22

7.27e-0820016894f7be296be0cd54cfc62cc93263fde26210c61f4
ToppCellfacs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l12|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DAB2 ITGAM TLR8 CSF3R TLR2 RASGEF1B CD53 NINJ1

2.93e-07171168826755e43d94e934106fc19ab929e4d34c17d6cba
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZWILCH SNX24 DAB2 BUB1 NCAPD2 RASGEF1B ATP13A3 CKAP2

4.33e-07180168843fd5c498a87bb078d101298b472656f3294686a
ToppCelldroplet-Lung-nan-3m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNX24 ACOX1 DAB2 DOCK10 TLR2 CARD11 ATP13A3 EPCAM

5.11e-0718416883261d767d5e3d9e9fbac22ad73ca14e44beed89c
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MYO5B BSPRY ADGRV1 ST3GAL5 PIK3C2G PRKCZ EPCAM CDH3

5.78e-071871688c2940aec30b3c2c113f6a65126dc6f1969cf301e
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 MYO5B ADGRV1 ST3GAL5 PIK3C2G PRKCZ EPCAM CDH3

5.78e-071871688db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 MYO5B ADGRV1 PLEKHG1 ST3GAL5 PRKCZ EPCAM CDH3

6.02e-071881688beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B ADGRV1 PLEKHG1 ST3GAL5 PIK3C2G PRKCZ EPCAM CDH3

6.52e-071901688625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MYO5B BSPRY ADGRV1 PIK3C2G CATSPERB PRKCZ EPCAM CDH3

7.05e-07192168839804d9ddc67c1b41887752df2503389eae44a1a
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MYO5B ADGRV1 ST3GAL5 PIK3C2G CATSPERB PRKCZ EPCAM CDH3

7.05e-0719216888898332387e5d746feb346ce1dabd6b2218fc6e5
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 MYO5B ADGRV1 ST3GAL5 PIK3C2G PRKCZ EPCAM CDH3

7.93e-071951688ce1ba5911e8a6ddb07434acc37147c38e94245ff
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 ADGRV1 ST3GAL5 PIK3C2G CATSPERB PRKCZ EPCAM CDH3

8.24e-0719616887b17d47b7758d8ccf9dbefd097aeb553791a1eed
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MYO5B ADGRV1 ST3GAL5 PIK3C2G CATSPERB PRKCZ EPCAM CDH3

8.56e-07197168822b26bac3a99b20c73bfa6e6f81026d064eaa9e8
ToppCellPCW_13-14-Epithelial|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 MYO5B ADGRV1 ST3GAL5 PIK3C2G PRKCZ EPCAM CDH3

8.89e-07198168848eb6f69a464a34ab32e8d425a22b9d45ec20428
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 FMO1 MYO5B KRT27 ST3GAL5 NANS EPCAM

1.91e-061531687e7a074ea8232bacf924be78a244a8507c7e1ebc8
ToppCelldroplet-Fat-Scat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 DCK ITGAM PLXNB2 RASGEF1B CD53 NINJ1

3.56e-061681687749eccebe4ee066f827d2a3980512f195f23ac27
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZWILCH PIWIL2 FBXO47 BUB1 NCAPD2 CKAP2 EPCAM

4.00e-061711687621f9da0bfa09c86fc89fd26919403e94cd56d2b
ToppCellfacs-Heart-RA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 DOCK10 ITGAM TLR8 ST3GAL5 TLR2 CD53

4.32e-0617316874fa5f502fa3ff8f888e279f68a0dafd91b37f26f
ToppCellfacs-Heart-RA-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 DOCK10 ITGAM TLR8 ST3GAL5 TLR2 CD53

4.32e-0617316875058cb5e3f2d57dbe947e1b113eb2bef7bf6dd7d
ToppCellfacs-Heart-RA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 DOCK10 ITGAM TLR8 ST3GAL5 TLR2 CD53

4.32e-061731687ea406b47ff3ead992bc06f6b1707c76eee574782
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZWILCH URB2 DCK NF1 BUB1 NCAPD2 CKAP2

4.49e-06174168772df66319f6efbd88ecf439013d97409fbf3cb52
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZWILCH URB2 DCK NF1 BUB1 NCAPD2 CKAP2

4.49e-061741687c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO5B BSPRY FANCI BUB1 NCAPD2 CKAP2 EPCAM

5.02e-061771687a68c3688f12aee22f3cb4049c4bccacbacb0fae6
ToppCellCOVID-19-kidney-Mito-rich_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

SAMD9 DOCK10 CSF3R TLR2 TMC8 CD53 CARD11

5.81e-0618116878448c2ad560cfd48bfe9dc1dd3a64373e6a622dd
ToppCelldroplet-Lung-nan-3m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNX24 ACOX1 DAB2 TLR2 CARD11 ATP13A3 EPCAM

6.25e-061831687ec3c05b9ce1e0fbb720e0dea41f1e28fd3fd878f
ToppCelldroplet-Lung-nan-18m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNX24 ACOX1 DAB2 DOCK10 TLR2 CARD11 ATP13A3

7.20e-061871687f0c6e53035b00772377c4d5f761b4d11026b911a
ToppCelldroplet-Lung-nan-18m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNX24 ACOX1 DAB2 DOCK10 TLR2 CARD11 ATP13A3

7.20e-061871687f20e7a1751694390f535ffb27b97e887220f8695
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNX24 ACOX1 DAB2 DOCK10 TLR2 CARD11 ATP13A3

7.71e-061891687287e59104687fe1665232c52993889f0f2c97f17
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B BSPRY ADGRV1 PIK3C2G PRKCZ EPCAM CDH3

7.71e-0618916875d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNX24 ACOX1 DAB2 DOCK10 TLR2 CARD11 ATP13A3

7.71e-061891687b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCelldroplet-Lung-LUNG-1m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNX24 ACOX1 DAB2 DOCK10 TLR2 CARD11 ATP13A3

7.71e-0618916876d24414ac6bd4f03f7a5ad3a6eba51d549a7b112
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 MYO5B ADGRV1 PLEKHG1 PRKCZ EPCAM CDH3

7.71e-0618916877659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNX24 ACOX1 DAB2 DOCK10 TLR2 CARD11 ATP13A3

7.98e-061901687da58227565ad6a690828dd8554dd3670222f8582
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B BSPRY ADGRV1 PLEKHG1 PRKCZ EPCAM CDH3

8.55e-061921687d3634574b2e8d2ded6446969361b70761b331aea
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B BSPRY ADGRV1 PIK3C2G PRKCZ EPCAM CDH3

8.55e-061921687b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B BSPRY ADGRV1 PLEKHG1 PRKCZ EPCAM CDH3

8.55e-0619216871aa5e4d9b32013a3f272561dcb8377f6805706df
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

NBEAL1 ADGRV1 ALG10B PIK3C2A DLG1 PCNX1 MED23

8.84e-061931687abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 ADGRV1 ST3GAL5 PIK3C2G PRKCZ EPCAM CDH3

9.14e-061941687c011cd59bb4ca4134331cba0f5d73bdbd7011d64
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNX24 DAB2 DCK NCAPD2 CARD11 ATP13A3 CKAP2

9.14e-061941687effd38e51062b225ecabc7e1c50154e65495d559
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK10 ITGAM CSF3R TLR2 TMC8 CD53 CARD11

9.14e-0619416870866ab6792cee274a71991d5c37a37f574ff446e
ToppCellPCW_05-06-Epithelial|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MYO5B BSPRY ADGRV1 PLEKHG1 PRKCZ EPCAM CDH3

9.14e-06194168747a1369c22fcbfe00b08376eb610a61c355548db
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 MYO5B ADGRV1 PLEKHG1 PRKCZ EPCAM CDH3

9.14e-061941687f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 MYO5B ADGRV1 ST3GAL5 PIK3C2G EPCAM CDH3

9.14e-061941687c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 ADGRV1 ST3GAL5 CATSPERB PRKCZ EPCAM CDH3

9.46e-061951687d67a2b489c29bfd575751c13d2a5b1efdec5240a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK10 ITGAM CSF3R TLR2 TMC8 CD53 CARD11

9.46e-0619516872d485373bfd9bb4bb9236bf0b31d03e132c8018f
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 MYO5B ADGRV1 CATSPERB PRKCZ EPCAM CDH3

9.46e-061951687d673f8844896d5c7b76a7bc7f6b88a039f1bc263
ToppCellproximal-3-Hematologic-IGSF21+_Dendritic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

URB2 CSF3R FANCI ALG10 TLR2 CARD11 ATM

9.46e-0619516878592d0332bc82a91e173680cfd1afc5ee189b289
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 MYO5B BSPRY ADGRV1 ST3GAL5 PIK3C2G EPCAM

9.46e-06195168798dd3b7d5ef587825dac052dea4d4ff883f6d4d6
ToppCellproximal-Hematologic-IGSF21+_Dendritic|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

URB2 CSF3R FANCI ALG10 TLR2 CARD11 ATM

9.46e-061951687c48ff83c48342875f06c6c9e7d5bc6084a992848
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK10 ITGAM CSF3R TLR2 TMC8 CD53 CARD11

9.46e-061951687ce8215d503cad3a9bc7d5d2be4adb57408015593
ToppCellproximal-Hematologic-IGSF21+_Dendritic-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

URB2 CSF3R FANCI ALG10 TLR2 CARD11 ATM

9.46e-061951687ae9d61011e95f7840cbb154738c79745fd29943e
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ATP13A4 MYO5B ADGRV1 LRCH1 ST3GAL5 CAMTA1 EPCAM

1.01e-051971687b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellNS-moderate-d_07-13-Myeloid-Non-resident_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DAB2 ITGAM TLR2 RASGEF1B CD53 NINJ1 ATP13A3

1.01e-051971687774a5053f43ac7d614c127ae7363d32a3a194f63
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK10 ITGAM PLEKHG1 TMC8 CD53 CARD11 SNX22

1.04e-051981687824461cf44098440ba8bc0df96735423ac65bda1
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_cell-B_mature|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK10 ITGAM PLEKHG1 TMC8 CD53 CARD11 SNX22

1.04e-051981687863765ccc0205dc28864dae85af339c283194c96
ToppCellPCW_10-12-Epithelial-Epithelial_airway|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 SLC27A6 ADGRV1 CATSPERB PRKCZ EPCAM CDH3

1.04e-0519816879a12e5e47236433e512c668005fe3f8be6fde95c
ToppCellHealthy_Control-Myeloid-Macrophages-FCN1+SPP1+|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CLGN ITGAM SLC38A2 TLR2 RASGEF1B NINJ1 ATP13A3

1.04e-051981687aa90326b82e21de37af5642df6a70a8b21af7f04
ToppCellcritical|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ITGAM DENND3 CSF3R TLR2 CD53 NINJ1 ATP13A3

1.08e-05199168716c55cb8a0e740342009965f0eddfb0ed2858fab
ToppCellNS-critical|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ITGAM DENND3 CSF3R TLR2 CD53 NINJ1 ATP13A3

1.08e-051991687f7c14dc9a9e659f89352dccf8954d6cbada011ab
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATP13A4 ZWILCH MYO5B FRMPD2 BUB1 SERPIND1

1.80e-051441686bdd6d00b2d1c9dad989df82367a60e8be79de816
ToppCelldroplet-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOX1 SERPINA12 ITIH4 SRPX2 CYP7B1 SLC38A3

1.88e-051451686f142b86d4da5b71c189da46cbc4beebdc387ffee
ToppCell356C-Lymphocytic-NK_cells-NK_cell_B1|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

ATP13A4 ADAM20 ITIH4 EDNRA PLEKHG1

2.09e-058816851ca0e16981e88030987412e12838a9797b97b9c9
ToppCellE16.5-samps-Myeloid-Fetal_macrophage-macrophage_-_intermediate_-_unactivated|E16.5-samps / Age Group, Lineage, Cell class and subclass

SP100 CLGN TLR8 KCNC2 TLR2 CD53

2.27e-05150168660fdd266aaca1b589b9a77465a4a7fad4921339a
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

TOPAZ1 NUP210L ADAM29 EYS KCNC2 RIMS2

2.27e-0515016860205318a870e091add66ee4305747dda9f51510d
ToppCellfacs-Aorta-Heart-3m-Epithelial-epithelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 CPB1 DNAJC6 ITIH4 CHRNG DNAH6

2.36e-0515116860de76acd1b204345dce7f33be2a1ed9fbe9e6da0
ToppCellfacs-Aorta-Heart-3m-Epithelial-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 CPB1 DNAJC6 ITIH4 CHRNG DNAH6

2.36e-05151168620b9c8fb966c5d62ff909cc4a4616b109b78cdca
ToppCellfacs-Aorta-Heart-3m-Epithelial|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 CPB1 DNAJC6 ITIH4 CHRNG DNAH6

2.36e-051511686bee48137d1f5f27a24571a59c835284651d38538
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOX1 SERPINA12 ITIH4 TIAM2 CYP7B1 SLC38A3

2.45e-051521686c21e2152b0130485659051d8fb7fb4589d1ec997
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

POGLUT3 NAALAD2 DNAH12 KIAA0825 FANCI DNAH6

2.94e-051571686410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NUP210L DOCK10 PIK3CB TLR2 RASGEF1B ATP13A3

3.27e-0516016866ed37d1fd0304932319d6b942502404115ff36a7
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 TOPAZ1 CPB1 ITIH4 HSD17B13 SLC38A3

3.38e-051611686b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 TOPAZ1 CPB1 ITIH4 HSD17B13 SLC38A3

3.38e-051611686f7a89c481f789f624102857be722c95fbeb47595
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

DOCK10 ACVR2A SLC38A2 TMC8 PCNX1 ATM

3.50e-051621686b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellfacs-MAT-Fat-3m-Myeloid-myeloid_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 ITGAM TLR8 CSF3R TLR2 NINJ1

3.63e-0516316865fc836444bc156c8248abee001b0ecbe43f980c9
ToppCellfacs-Lung-3m-Hematologic-myeloid-neutrophil-neutrophil|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TLR6 DCK ITGAM CSF3R TLR2 CD53

4.01e-0516616863195035445d35d820f5e00dd03b029730478b024
ToppCelldroplet-Spleen-nan-18m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE ITGAM PLXNB2 TLR8 TIAM2 CSF3R

4.01e-051661686e841e62cb20235d6233f78f4155fb8c0ffb1ef1b
ToppCellfacs-Lung-3m-Hematologic-myeloid-neutrophil|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TLR6 DCK ITGAM CSF3R TLR2 CD53

4.01e-0516616866b6ecd70264b6bfbd8a3a378c965702829e2ecf1
ToppCelldroplet-Spleen-nan-18m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE ITGAM PLXNB2 TLR8 TIAM2 CSF3R

4.01e-0516616863ca3ddb663644f0e7f70f9b75833bb54cd9191d3
ToppCelldroplet-Spleen-nan-18m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE ITGAM PLXNB2 TLR8 TIAM2 CSF3R

4.01e-051661686f751cbd01d4978ded7755874ab60504f6291afd7
ToppCellfacs-Kidney-nan-3m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCK ITGAM TLR8 CSF3R TLR2 CD53

4.15e-051671686991a93e1075d562b7391f0689b2f62c1351d48d1
ToppCellfacs-Kidney-nan-3m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCK ITGAM TLR8 CSF3R TLR2 CD53

4.15e-051671686f22d1471c785b30d096ec5cdc68974e850ed7de0
ToppCellfacs-Kidney-nan-3m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCK ITGAM TLR8 CSF3R TLR2 CD53

4.15e-051671686934905aeaafbc215ec8f6a7903498b0e258b9220
ToppCellPND14-Immune-Immune_Myeloid-Dendritic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UST SAMD15 ST3GAL5 NCAPD2 CARD11 CKAP2

4.29e-0516816869b8a74abb83c64f0b5829dcb4275f722c82b45dc
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UST SAMD15 ST3GAL5 NCAPD2 CARD11 CKAP2

4.29e-0516816864b152b8d0f4a66faf664dfacb7914b18d60ce64a
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE ITGAM PLXNB2 TIAM2 ST3GAL5 SPATA13

4.29e-0516816864b5be7c6662eceddf90a65015f12908278d1664e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE ITGAM PLXNB2 TIAM2 ST3GAL5 SPATA13

4.29e-051681686689c41f6e9f65381570991cc311cba49a57ec955
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UST SAMD15 ST3GAL5 NCAPD2 CARD11 CKAP2

4.29e-051681686c3169ad8f4130ef18777ed86770bb722ffb5db85
ToppCellNS-critical-d_0-4-Lymphoid-B_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PLEKHG1 SACS PRIM2 TXNDC16 TARBP1 SNX22

4.74e-051711686bd1ebd9037a740ad8c01c460d778b0973d8b56df
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGAM TGM4 FANCI TLR2 BUB1 TMC8

4.89e-051721686ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DAB2 CSF3R TLR2 BUB1 NCAPD2 RASGEF1B

5.05e-05173168612c6875f881cb0fbff09d753b53c1cce7a95527f
ToppCellfacs-Trachea-nan-3m-Myeloid-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 ITGAM TLR8 TLR2 RASGEF1B CD53

5.05e-051731686e4eb2ac2cee16bfa8eabc938f8030ee161c972c5
ToppCellfacs-Trachea-nan-3m-Myeloid|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 ITGAM TLR8 TLR2 RASGEF1B CD53

5.05e-051731686371515471459307a3b2adce735263b4aac828956
ToppCellfacs-Trachea-nan-3m-Myeloid-macrophage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 ITGAM TLR8 TLR2 RASGEF1B CD53

5.05e-0517316864e9b6c71030ae0d63d54e7255e4a10b25970fcc4
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD53 SLC38A2 PIK3C2A MTOR PCNX1 PRKAG2

5.22e-051741686f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
DrugCP-863187 [668981-07-5]; Down 200; 10uM; PC3; HT_HG-U133A

SP100 BCR EDNRA MOXD1 NF1 BUB1 CD53 PCNX1 ATP13A3 ZNF839

1.42e-06194163107558_DN
Drugimiquimod

TLR6 PTCH1 ITGAM TLR8 TGM4 IFIH1 TLR2 TMC8

5.04e-061321638CID000057469
DrugZSTK474

PIK3C2A PIK3C2G PIK3CB MTOR

5.60e-06171634CID011647372
DrugNVP-BEZ235

PIK3C2A PIK3C2G PIK3CB MTOR

7.16e-06181634CID011977753
DrugPX-866

PIK3C2A PIK3C2G PIK3CB MTOR

1.12e-05201634CID009849735
Diseasecortical surface area measurement

SAMD9 SLC27A6 NBEAL1 DOCK10 ADGRV1 ACVR2A PTCH1 BCR PLXNB2 LRCH1 DENND3 SLC38A2 PLEKHG1 NPRL2 THADA KIAA0825 RASGEF1B EXOC6B PRKCZ PRKAG2 MED23 SOS1

2.54e-06134515622EFO_0010736
Diseasemyocardial infarction (implicated_via_orthology)

DAB2 ACE EDNRA CS MTOR

2.67e-05661565DOID:5844 (implicated_via_orthology)
Diseaseneuroimaging measurement

SAMD9 SLC27A6 SNX24 NBEAL1 PTCH1 BCR PLXNB2 LRCH1 DENND3 EFTUD2 PLEKHG1 THADA NF1 PRKCZ CAMTA1 PRKAG2 HTT

5.43e-05106915617EFO_0004346
DiseaseFamilial focal epilepsy with variable foci

NPRL2 DEPDC5

8.30e-0531562cv:C1858477
DiseaseLong Qt Syndrome 2

ALG10B ALG10

8.30e-0531562C3150943
DiseaseEpilepsy, Partial, with Variable Foci

NPRL2 DEPDC5

8.30e-0531562C1858477
Diseasemean platelet volume

SNX24 NUP210L PCDHGA6 ACOX1 U2SURP DOCK10 LRCH1 SRPX2 ST3GAL5 PIK3CB NFE2L1 ALG9 CATSPERB ATP13A3 CAMTA1 HTT

1.07e-04102015616EFO_0004584
DiseaseMultiple pterygium syndrome

MYH3 CHRNG

1.65e-0441562C0265261
Diseasefocal epilepsy (is_implicated_in)

NPRL2 DEPDC5

1.65e-0441562DOID:2234 (is_implicated_in)
Diseasebacterial pneumonia (implicated_via_orthology)

TLR6 TLR2

1.65e-0441562DOID:874 (implicated_via_orthology)
Diseasejuvenile-onset Parkinson's disease (implicated_via_orthology)

ATP13A4 ATP13A3

1.65e-0441562DOID:0060893 (implicated_via_orthology)
DiseaseKufor-Rakeb syndrome (implicated_via_orthology)

ATP13A4 ATP13A3

1.65e-0441562DOID:0060556 (implicated_via_orthology)
Diseaseleukemia

NF1 CSF3R PRKCZ ATM

2.08e-04551564C0023418
Diseasemetabolic acidosis (biomarker_via_orthology)

DAB2 SLC38A3

2.75e-0451562DOID:0050758 (biomarker_via_orthology)
DiseaseStaphylococcus aureus infection

ACE TLR2

2.75e-0451562C1318973
DiseaseStaphylococcal Infections

ACE TLR2

2.75e-0451562C0038160
Diseasecutaneous melanoma, hair color

ADGRV1 BCR PLXNB2 CDH3

3.30e-04621564EFO_0000389, EFO_0003924
Diseasenonsyndromic deafness (implicated_via_orthology)

ALG10B ALG10

4.11e-0461562DOID:0050563 (implicated_via_orthology)
Diseasealcohol dependence

CLGN ALG10B ALG10 PCNX1 CAMTA1 SPATA13

4.41e-041831566MONDO_0007079
DiseaseMYELODYSPLASTIC SYNDROME

SAMD9 CSF3R FANCI TLR2

4.45e-04671564C3463824
Diseasesodium measurement, diastolic blood pressure

CLGN UST

5.73e-0471562EFO_0006336, EFO_0009282
Diseaseneutropenia (implicated_via_orthology)

ITGAM CSF3R

5.73e-0471562DOID:1227 (implicated_via_orthology)
Diseaseasphyxia neonatorum

OR4E2 THADA RASGEF1B

6.42e-04321563EFO_1000824
DiseaseParkinson's disease (is_implicated_in)

DNAJC6 VPS35 ATM HTT

7.17e-04761564DOID:14330 (is_implicated_in)
Diseaseobstructive sleep apnea (biomarker_via_orthology)

ACE EDNRA

7.62e-0481562DOID:0050848 (biomarker_via_orthology)
DiseaseIntestinal Diseases

SAMD9 MYO5B

7.62e-0481562C0021831
Diseasefemale breast cancer (is_implicated_in)

FANCI ATM

7.62e-0481562DOID:0050671 (is_implicated_in)
Diseasecortical thickness

SLC27A6 NBEAL1 NUP210L ARFGEF2 ADGRV1 PTCH1 LRCH1 DENND3 PLEKHG1 NPRL2 THADA KIAA0825 PRKCZ CAMTA1 PRKAG2

8.59e-04111315615EFO_0004840
DiseaseSchizophrenia

MYO5B GRIN2C ACE ITGAM SLC38A2 NPRL2 PIK3CB MTOR VPS35 TLR2 DLG1 ATM RIMS2

8.65e-0488315613C0036341
Diseasewhite matter microstructure measurement

NBEAL1 PTCH1 EFTUD2 PLEKHG1 CATSPERB CARD11 PRKAG2 SOS1

1.15e-033901568EFO_0005674
Diseasewhite matter hyperintensity measurement

NBEAL1 ACOX1 DENND3 PLEKHG1 ST3GAL5 CATSPERB TARBP1

1.17e-033021567EFO_0005665
Diseasenevus count, cutaneous melanoma

ADGRV1 PLXNB2 ATM CDH3

1.41e-03911564EFO_0000389, EFO_0004632
Diseaseobstructive sleep apnea (is_implicated_in)

ACE EDNRA

1.48e-03111562DOID:0050848 (is_implicated_in)
DiseaseParkinson's disease (implicated_via_orthology)

ATP13A4 PTCH1 DNAJC6 VPS35 ATP13A3

1.51e-031571565DOID:14330 (implicated_via_orthology)
Diseaseplatelet crit

POGLUT3 SNX24 NUP210L U2SURP DOCK10 ADGRV1 FBXO47 EDNRA THADA NF1 NFE2L1 CDH3 SPATA13

1.70e-0395215613EFO_0007985
DiseaseMethionine sulfoxide measurement

FMO1 FMO4

1.77e-03121562EFO_0021650
Diseaselung disease (implicated_via_orthology)

ACE TLR2

2.08e-03131562DOID:850 (implicated_via_orthology)
Diseasehyperglycemia (is_marker_for)

PTCH1 ITGAM

2.08e-03131562DOID:4195 (is_marker_for)
Diseaseintermediate coronary syndrome (is_marker_for)

ACE ITGAM

2.08e-03131562DOID:8805 (is_marker_for)
Diseaseleukemia (is_implicated_in)

ACE BCR

2.08e-03131562DOID:1240 (is_implicated_in)
DiseaseMalignant neoplasm of pancreas

PTCH1 BUB1 ATM EPCAM

2.14e-031021564C0346647
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GRIN2C PLXNB2 DLG1

2.23e-03491563DOID:0060037 (implicated_via_orthology)
DiseaseTobacco Dependence

PLEKHG1 RPTOR

2.42e-03141562C0040332
Diseaseneuronal ceroid lipofuscinosis (implicated_via_orthology)

ATP13A4 ATP13A3

2.42e-03141562DOID:14503 (implicated_via_orthology)
DiseaseNicotine Dependence

PLEKHG1 RPTOR

2.42e-03141562C0028043
DiseaseNicotine Use Disorder

PLEKHG1 RPTOR

2.42e-03141562C0376384
Diseasemyocardial infarction

NBEAL1 EDNRA PLEKHG1 THADA PRIM2 RASGEF1B HTT

2.68e-033501567EFO_0000612
DiseaseIntellectual Disability

FBXL3 AP2M1 NF1 ST3GAL5 SACS MTOR MED23 HTT

2.69e-034471568C3714756
Diseasebrain measurement, neuroimaging measurement

SLC27A6 SNX24 PTCH1 LRCH1 DENND3 THADA CATSPERB PRKCZ PRKAG2

2.71e-035501569EFO_0004346, EFO_0004464
Diseasecongenital disorder of glycosylation type I (implicated_via_orthology)

ALG9 ALG5

2.79e-03151562DOID:0050570 (implicated_via_orthology)
DiseaseNeoplasm of uncertain or unknown behavior of bladder

MTOR ATM

2.79e-03151562C0496930
DiseaseBenign neoplasm of bladder

MTOR ATM

2.79e-03151562C0154017
DiseaseCarcinoma in situ of bladder

MTOR ATM

2.79e-03151562C0154091
DiseaseRASopathy

NF1 SOS1

2.79e-03151562cv:C5555857
DiseaseCongestive heart failure

ACE EDNRA CS TLR2

2.81e-031101564C0018802
DiseaseHeart failure

ACE EDNRA CS TLR2

2.81e-031101564C0018801
DiseaseLeft-Sided Heart Failure

ACE EDNRA CS TLR2

2.81e-031101564C0023212
DiseaseHeart Failure, Right-Sided

ACE EDNRA CS TLR2

2.81e-031101564C0235527
DiseaseHeart Decompensation

ACE EDNRA CS TLR2

2.81e-031101564C1961112
DiseaseMyocardial Failure

ACE EDNRA CS TLR2

2.81e-031101564C1959583
DiseaseAcute Cerebrovascular Accidents

ACE LRCH1 EDNRA

2.95e-03541563C0751956
Diseasecancer (implicated_via_orthology)

PIK3CB MTOR CD53 DLG1 DEPDC5 ATM

3.10e-032681566DOID:162 (implicated_via_orthology)
DiseaseMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse

MTOR ATM

3.17e-03161562C0334634
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

ACE MTOR

3.17e-03161562DOID:0110861 (implicated_via_orthology)
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

BUB1 NCAPD2

3.17e-03161562DOID:0070296 (is_implicated_in)
Diseasecreatinine measurement, glomerular filtration rate

DAB2 ACVR2A THADA PRKAG2

3.51e-031171564EFO_0004518, EFO_0005208
Diseaserenal fibrosis (implicated_via_orthology)

ACE TLR2

3.59e-03171562DOID:0050855 (implicated_via_orthology)
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

TLR6 TLR2

3.59e-03171562DOID:8677 (biomarker_via_orthology)
Diseasemean reticulocyte volume

OR11L1 POGLUT3 SAMD9 NUP210L URB2 THADA MTOR ALG9 POLI ATM CDH3

3.59e-0379915611EFO_0010701
DiseaseCarcinoma of bladder

MTOR ATM

4.02e-03181562C0699885
DiseaseCerebrovascular accident

ACE LRCH1 EDNRA

4.36e-03621563C0038454
Diseasehypertension, white matter hyperintensity measurement

NBEAL1 PLEKHG1 TARBP1

4.36e-03621563EFO_0000537, EFO_0005665
Diseaseangina pectoris

NBEAL1 DHX38 EDNRA PRIM2

4.44e-031251564EFO_0003913
Diseaseportal hypertension (implicated_via_orthology)

EDNRA MTOR

4.48e-03191562DOID:10762 (implicated_via_orthology)
Diseasecerebral infarction (is_marker_for)

ITGAM SOS1

4.48e-03191562DOID:3526 (is_marker_for)
Diseasemelanoma

POGLUT3 ADGRV1 EYS ATM

4.57e-031261564EFO_0000756
Diseaseend stage renal disease (implicated_via_orthology)

ACE MTOR

4.96e-03201562DOID:783 (implicated_via_orthology)
DiseaseCardiomyopathies

CS TLR2 PRKAG2 SOS1

5.10e-031301564C0878544

Protein segments in the cluster

PeptideGeneStartEntry
LVLEKFQSLVLPYLQ

URB2

516

Q14146
ILQINDFAYEIKPLA

ADAM29

126

Q9UKF5
FAYLTIKDRIPQILT

ARMT1

16

Q9H993
LDPKFITSILYENNV

EPCAM

176

P16422
ELYLQETFKPLVNIS

PRKAG2

351

Q9UGJ0
EVTLAILLFVYEQKL

CD53

96

P19397
EYFQTRQEKLLPTAL

CAMTA1

1251

Q9Y6Y1
ENFPENKEYLITLLE

BUB1

36

O43683
PQENEIIKLYLFLEN

CATSPERB

41

Q9H7T0
ALPAQELEEYNKILL

ACE

731

P12821
QQIETIFFKVPELYE

BCR

541

P11274
LQINDLVYEIKPISV

ADAM20

136

O43506
LLIKEVLNPFYIFQL

ATP13A3

206

Q9H7F0
KLLIKEVLNPFYIFQ

ATP13A4

196

Q4VNC1
LKPENILFVNSDYEL

CLK2

291

P49760
LIQRKPLFYVINIIA

CHRNG

236

P07510
DVELLYIAQFFKIPI

ALG5

261

Q9Y673
KLVIAPLNIVLYNVF

ALG9

276

Q9H6U8
LLNEYVAVKIFPIQD

ACVR2A

211

P27037
KRLQIAQLYPISIFI

DLG1

816

Q12959
KYIFINITDNSIPEL

ADGRV1

1786

Q8WXG9
QLELIQTIDNIVFYP

ARFGEF2

1556

Q9Y6D5
DLIYVVIDLPINVFK

EDNRA

126

P25101
VIVPQKLLEFRYFIL

ALG10B

406

Q5I7T1
EPFYLENIKNRTLLT

LVRN

591

Q6Q4G3
SYINIFLRLQKFLPE

HSD17B13

261

Q7Z5P4
QNLYKTDIRIFPTDL

DENND3

581

A2RUS2
VQDTVYPLLALVAIF

DISP2

486

A7MBM2
PIENIIAIYEKAILA

CKAP2

476

Q8WWK9
PNAKITFELVYEELL

ITIH4

136

Q14624
INLPVEEFNELLSKY

NFE2L1

631

Q14494
IKEQTEIYSFLIPLV

NBEAL1

1626

Q6ZS30
DELLEYLPQLVQAVK

PIK3C2G

751

O75747
EVYLKAPLDFEIIQS

PCDHB18P

246

Q96TA0
APLDFEIIQSYIINI

PCDHB18P

251

Q96TA0
VNDLYIQKQFPILLD

SERPIND1

221

P05546
LFRPLLNKYEQETLE

ANO10

51

Q9NW15
ELLQKILEAPDFYVQ

ANKRD13A

111

Q8IZ07
LQVLVEEYKFPVDLL

ANKRD53

156

Q8N9V6
EPLVVDLKDLFQVIY

DAB2

156

P98082
KLFIQYPVLVRLEQA

DEPDC5

276

O75140
PNLIFAIEQYEKFLI

FANCI

1251

Q9NVI1
SDYPQLQKVLFVLIL

OR2G2

21

Q8NGZ5
FNILVEDKLNLYPVE

PCDHGA6

106

Q9Y5G7
NIIDFVAILPFYLEV

KCNC2

316

Q96PR1
FELNLQIYPDVTLKT

EYS

1746

Q5T1H1
LQQLLFLYPESEVII

KIAA0825

196

Q8IV33
FVEKNIIYPLIVLNE

PCNX1

1356

Q96RV3
TLFLELLEQYVVAKN

PLXNB2

1371

O15031
LTDLLPQFVQALKYE

PIK3C2A

971

O00443
LYKQVFPLNLERATL

FMO4

351

P31512
VCYFIIQLLLLKPND

MED23

881

Q9ULK4
VLKLNLTPYLEQFEV

DNAH12

801

Q6ZR08
TNYSLVPLQILLEKV

PRAMEF15

336

P0DUQ1
SRYFPIIDELKNQII

KRT27

136

Q7Z3Y8
SRYFPIIDDLKNQII

KRT25

131

Q7Z3Z0
NYLKVLPQELVDLSL

LRCH1

221

Q9Y2L9
IKNNFVLIYELLDEI

AP2M1

101

Q96CW1
KYLEEFITNITNVLP

EXOC6B

571

Q9Y2D4
LLPEINKIISVFYTV

OR11L1

266

Q8NGX0
LQDYVTIIENFPSLK

DEFB127

81

Q9H1M4
RKILQYLLTVPVFSE

RASGEF1B

426

Q0VAM2
VLLIFLVKYDLNNPA

NINJ1

96

Q92982
DKVAALFYTVINPLL

OR9G4

286

Q8NGQ1
RKTLEPLYQQLLSFE

RIMS2

1316

Q9UQ26
FAYVPLKDIVAIILN

PRIM2

206

P49643
ILDFQTQQYKLFPLL

ACOX1

321

Q15067
DNENLYITIKLLDPF

ATM

1551

Q13315
SLQEFKDYIENLPLI

DNAH6

3796

Q9C0G6
QLIPVISDYLLSNLK

HTT

2801

P42858
VVLDLQVQELLFYEP

BSPRY

356

Q5W0U4
ALYFNPIINIDLVVK

BFAR

426

Q9NZS9
YELIADVNKPIIAVF

DOCK10

1826

Q96BY6
QDIILQVFKYLPLLD

FBXL3

41

Q9UKT7
AELKFLRVTQQLPEY

FRMPD2

531

Q68DX3
FLLLQDKQPLAYVVQ

FRMPD3

236

Q5JV73
AKLQYLRILNELPTF

FRMPD3

381

Q5JV73
LVAQLYKIVPNVLLE

CS

376

O75390
IDELLTYINAKPNLF

FMO1

436

Q01740
VLDYLTFLPAEVKEQ

IFIH1

31

Q9BYX4
EKYPQLFQVTLDVEL

DNAJC6

351

O75061
KENIRPFQLYEIIVT

CSF3R

491

Q99062
ELLKSLPYLVEVFTN

MARF1

1461

Q9Y4F3
QVLYFLISQTPLLKE

CDH26

201

Q8IXH8
ALPLEIFQIILKYLS

FBXO47

46

Q5MNV8
LKTNFDYLQEVPILT

DCK

221

P27707
DKFAYLVSNIPIELL

CYP7B1

221

O75881
PEYEITQSLVFLLLA

ZMPSTE24

116

O75844
QVFYELPEAVQKELL

POLI

711

Q9UNA4
YEFLQPLQKLLNVSE

SAMD15

476

Q9P1V8
ALIAPAYVELLIQLK

SACS

2916

Q9NZJ4
NYSLVPLQILLEKVA

PRAMEF26

241

H0Y7S4
LLDKLDFYVLPVLNI

CPB1

206

P15086
TRDLIKSNIYPIVLF

CARD11

1061

Q9BXL7
LYVEVTNEAPFVLKL

CDH3

406

P22223
LAVYNQLLNIFPKEV

ECSIT

126

Q9BQ95
IYEIKVDTFQQLLSL

LGR5

386

O75473
EVQILVFEKLQLFYP

NUP210L

1281

Q5VU65
VQLKNLPFYDVLDVL

PIAS2

146

O75928
YPTLLEVLLNFLKTE

MTOR

861

P42345
IPDIINEILTFKVDY

MAP3K4

291

Q9Y6R4
ELYPFLLKQLETVAN

THADA

1291

Q6YHU6
LYIIKSELPLVIQTF

SLC38A3

161

Q99624
DVLEYVVFEKQLTNP

MRPL45

241

Q9BRJ2
GSILYLPVKLQQVLE

PIWIL2

276

Q8TC59
YTIQILQLIPFFDNK

SAMD9

1206

Q5K651
TNYSLVPLQILLEKV

PRAMEF25

336

A6NGN4
PLEFLEELKKINYQV

PTCH1

261

Q13635
YQLDRITPTQVEKFL

POLR3A

1001

O14802
NLRVISEYQKLFPDI

NANS

196

Q9NR45
PVIIKETAFDILQYS

ST3GAL5

311

Q9UNP4
IFYQILSNKKPELIE

MYH3

286

P11055
TNYSLVPLQILLEKV

PRAMEF27

336

A3QJZ7
ILKSEENILYLLFNP

TGM4

126

P49221
NKTEFQLELPVKYAV

ITGAM

911

P11215
LFDTVQVYIITKPEL

NPRL2

36

Q8WTW4
SQYLLQLVQVLKYEP

PIK3CB

636

P42338
FKEAVQYVLPRLLLA

SOS1

331

Q07889
LLNPFIYSLRNKEVI

OR5K4

281

A6NMS3
VALQFIEEEKNYALP

RPTOR

681

Q8N122
EIPYQKNITAIFILP

SERPINA12

261

Q8IW75
AIYPEPFLIKLQNIF

U2SURP

661

O15042
VIVPQKLLEFRYFIL

ALG10

406

Q5BKT4
IFADKPLIVQYEVNF

CLGN

131

O14967
PFKEVAVTLIYQLAE

NCAPD2

866

Q15021
LLEELVLKLQPQTYS

CNGA4

356

Q8IV77
YPLQLAELLKYTTQE

SPATA13

386

Q96N96
TRKVLLPDLEFYVNL

POGLUT3

226

Q7Z4H8
TNYSLVPLQILLEKV

PRAMEF4

336

O60810
YSLVPLQILLEKVAA

PRAMEF6

336

Q5VXH4
ELIKNISTAEQPYLF

UST

151

Q9Y2C2
LPRLEILDLSFNYIK

TLR8

336

Q9NR97
DPVLFQLYKDLVVSQ

GTF2H1

121

P32780
EDLLKFIQLNRISYP

TXNDC16

486

Q9P2K2
PFLYEADVQVQLISK

ZWILCH

31

Q9H900
DNKEESLFLLLQYLP

TMC8

326

Q8IU68
VNKLDIVEFIPSLLY

TM9SF4

591

Q92544
IEVFPLNVYDVQLTK

TIAM2

881

Q8IVF5
FQEFQYLKEEQTILP

MOXD1

421

Q6UVY6
LLNPFIYTLRNEEVK

OR4E2

281

Q8NGC2
YLQAVILENEELPKL

SNX24

81

Q9Y343
DQFYEKQRLLIISAP

SRPX2

336

O60687
LFIVKYELPLVIQAL

SLC38A2

166

Q96QD8
LLKIPVDTYNNILTV

VPS35

401

Q96QK1
TNYSLVPLQILLEKV

PRAMEF9

336

P0DUQ2
VYNVLSELEKTFNLP

SP100

106

P23497
YSLVPLQILLEKVAA

PRAMEF5

336

Q5TYX0
PILQKLQELVDQLYS

TTC5

11

Q8N0Z6
QTQIPDYAELIVKFL

NF1

2721

P21359
TNYSLVPLQILLEKV

PRAMEF11

336

O60813
YLPIFAVQQELLTII

DHX38

531

Q92620
LIDKVLPESYFVNNL

TBC1D30

366

Q9Y2I9
LYLNQEVPKELLEFL

SNX22

91

Q96L94
KPVEYLNIYNLTIIE

TLR6

276

Q9Y2C9
LPQLAQVVTVYEFLL

ZNF839

371

A8K0R7
LPSLKILLNIFEYVA

TOPAZ1

1196

Q8N9V7
YNQLLKPTLSEIELF

SNRNP200

1001

O75643
LYDQIVFRESPLKIQ

PLEKHG1

1041

Q9ULL1
QKFLVTYISLLPEEI

TARBP1

451

Q13395
YVPDILKLFNEFIQL

WDR3

831

Q9UNX4
EFILEPLYKILAQVV

EFTUD2

371

Q15029
LDLEKVYEQVVTFLP

SLC27A6

536

Q9Y2P4
LFSLNLPQLKELYIS

TLR2

471

O60603
EFISELAEYLIKPLN

UFL1

496

O94874
LLLVEAAVQKAIPEY

ATP6V1E2

141

Q96A05
NIVDVLAILPFYVSL

KCNF1

256

Q9H3M0
NTEDYLFQVILEKPI

PRKCZ

461

Q05513
ELVDSKIIPFNIQDY

NAALAD2

576

Q9Y3Q0
QIVKILNLYTPLNEF

MYO5B

1771

Q9ULV0
LEQQLQVLFKVLEEY

GRIN2C

146

Q14957