Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsphingolipid delta-4 desaturase activity

DEGS2 DEGS1

1.83e-052862GO:0042284
GeneOntologyMolecularFunctionantigen binding

IGLV1-47 IGHV3-30 IGHV3-30-5 IGHV3-30-3 IGLV3-25 IGLV3-19

1.72e-04190866GO:0003823
GeneOntologyBiologicalProcessadaptive immune response

SLFN12L TRAV5 IL31RA IGLV1-47 IGHV3-30 IGHV3-30-5 TRA IGKV6D-41 IGHV3-30-3 IGKV2D-29 IL1RL1 TRAV38-2DV8 IGLV9-49 IGKV2-29 IGLV3-25 IGLV3-19 IGLV3-16

1.53e-078389217GO:0002250
GeneOntologyBiologicalProcessimmunoglobulin production

IGLV1-47 IGKV6D-41 IGKV2D-29 TRAV38-2DV8 IGLV9-49 IGKV2-29 IGLV3-25 IGLV3-19 IGLV3-16

1.31e-06241929GO:0002377
GeneOntologyBiologicalProcessregulation of Rab protein signal transduction

DENND4A DENND4B DENND4C

1.70e-066923GO:0032483
GeneOntologyBiologicalProcessproduction of molecular mediator of immune response

IL31RA IGLV1-47 IGKV6D-41 IGKV2D-29 TRAV38-2DV8 IGLV9-49 IGKV2-29 IGLV3-25 IGLV3-19 IGLV3-16

1.26e-054039210GO:0002440
GeneOntologyBiologicalProcessRab protein signal transduction

DENND4A DENND4B DENND4C

1.08e-0421923GO:0032482
GeneOntologyCellularComponentimmunoglobulin complex

IGLV1-47 IGHV3-30 IGHV3-30-5 IGKV6D-41 IGHV3-30-3 IGKV2D-29 IGLV9-49 IGKV2-29 IGLV3-25 IGLV3-19 IGLV3-16

2.22e-101669411GO:0019814
GeneOntologyCellularComponentomegasome

ATG14 TRIM5

1.98e-045942GO:1990462
DomainPPR

DENND4A DENND4B DENND4C

4.33e-068813PS51375
DomainDES1/DES2

DEGS2 DEGS1

1.86e-052812IPR011388
DomainLipid_DES

DEGS2 DEGS1

1.86e-052812PF08557
DomainSphingolipid_d4-desaturase_N

DEGS2 DEGS1

1.86e-052812IPR013866
DomainDUF1088

NBEA LRBA

1.86e-052812IPR010508
DomainDUF1088

NBEA LRBA

1.86e-052812PF06469
DomainLipid_DES

DEGS2 DEGS1

1.86e-052812SM01269
DomainUDENN

DENND4A DENND4B DENND4C

4.23e-0516813PS50946
DomainDDENN

DENND4A DENND4B DENND4C

4.23e-0516813PS50947
DomainDENN

DENND4A DENND4B DENND4C

4.23e-0516813SM00799
DomaindDENN

DENND4A DENND4B DENND4C

4.23e-0516813SM00801
DomainDENN

DENND4A DENND4B DENND4C

4.23e-0516813PF02141
DomaindDENN_dom

DENND4A DENND4B DENND4C

4.23e-0516813IPR005112
DomainuDENN_dom

DENND4A DENND4B DENND4C

4.23e-0516813IPR005113
DomaindDENN

DENND4A DENND4B DENND4C

4.23e-0516813PF03455
DomainDENN

DENND4A DENND4B DENND4C

4.23e-0516813PS50211
DomainDENN_dom

DENND4A DENND4B DENND4C

4.23e-0516813IPR001194
Domain-

TCERG1 PRPF40B

1.11e-0448121.10.10.440
Domain-

GTF2IRD2B GTF2IRD2

1.11e-0448123.90.1460.10
DomainMABP

DENND4A DENND4B

1.11e-044812IPR023341
DomainPPR

DENND4A DENND4C

1.11e-044812PF01535
DomainGTF2I

GTF2IRD2B GTF2IRD2

1.11e-044812PS51139
DomainMABP

DENND4A DENND4B

1.11e-044812PS51498
DomainGTF2I

GTF2IRD2B GTF2IRD2

1.11e-044812PF02946
DomainGTF2I

GTF2IRD2B GTF2IRD2

1.11e-044812IPR004212
DomainPentatricopeptide_repeat

DENND4A DENND4B DENND4C

1.31e-0423813IPR002885
DomainCu_oxidase_CS

CP F5

1.84e-045812IPR033138
DomainDUF4704

NBEA LRBA

1.84e-045812IPR031570
DomainCu-oxidase_3

CP F5

1.84e-045812IPR011707
DomainDUF4704

NBEA LRBA

1.84e-045812PF15787
DomainMULTICOPPER_OXIDASE1

CP F5

1.84e-045812PS00079
DomainCu-oxidase_3

CP F5

1.84e-045812PF07732
DomainFF

TCERG1 PRPF40B

2.76e-046812PF01846
DomainFF

TCERG1 PRPF40B

2.76e-046812SM00441
DomainFF_domain

TCERG1 PRPF40B

2.76e-046812IPR002713
DomainPH_BEACH

NBEA LRBA

2.76e-046812PF14844
DomainFF

TCERG1 PRPF40B

2.76e-046812PS51676
DomainCu_oxidase_Cu_BS

CP F5

2.76e-046812IPR002355
DomainPH-BEACH_dom

NBEA LRBA

5.11e-048812IPR023362
DomainFA_desaturase_dom

DEGS2 DEGS1

5.11e-048812IPR005804
DomainFA_desaturase

DEGS2 DEGS1

5.11e-048812PF00487
Domain-

NBEA LRBA

5.11e-0488122.30.29.40
DomainPH_BEACH

NBEA LRBA

5.11e-048812PS51783
DomainBEACH_dom

NBEA LRBA

6.56e-049812IPR000409
DomainBEACH

NBEA LRBA

6.56e-049812PS50197
DomainBeach

NBEA LRBA

6.56e-049812PF02138
Domain-

NBEA LRBA

6.56e-0498121.10.1540.10
DomainBeach

NBEA LRBA

6.56e-049812SM01026
DomainWW

TCERG1 PRPF40B WAC

1.11e-0347813PF00397
DomainWW

TCERG1 PRPF40B WAC

1.18e-0348813SM00456
DomainWW_DOMAIN_2

TCERG1 PRPF40B WAC

1.41e-0351813PS50020
DomainWW_DOMAIN_1

TCERG1 PRPF40B WAC

1.41e-0351813PS01159
DomainWW_dom

TCERG1 PRPF40B WAC

1.49e-0352813IPR001202
Domain-

CP F5

1.63e-03148122.60.40.420
DomainDynein_heavy_chain_D4_dom

DNAH12 DNAH2

1.63e-0314812IPR024317
DomainDynein_heavy_dom-2

DNAH12 DNAH2

1.63e-0314812IPR013602
DomainDHC_N2

DNAH12 DNAH2

1.63e-0314812PF08393
DomainAAA_8

DNAH12 DNAH2

1.63e-0314812PF12780
DomainuDENN

DENND4A DENND4B

1.63e-0314812SM00800
DomainATPase_dyneun-rel_AAA

DNAH12 DNAH2

1.63e-0314812IPR011704
DomainAAA_5

DNAH12 DNAH2

1.63e-0314812PF07728
DomainDHC_fam

DNAH12 DNAH2

1.88e-0315812IPR026983
DomainDynein_heavy_dom

DNAH12 DNAH2

1.88e-0315812IPR004273
DomainuDENN

DENND4A DENND4B

1.88e-0315812PF03456
DomainDynein_heavy

DNAH12 DNAH2

1.88e-0315812PF03028
DomainCupredoxin

CP F5

4.06e-0322812IPR008972
PathwayREACTOME_CD22_MEDIATED_BCR_REGULATION

IGLV1-47 IGHV3-30 IGLV3-25 IGLV3-19

1.76e-0461654M27581
PathwayREACTOME_FCGR_ACTIVATION

IGLV1-47 IGHV3-30 IGLV3-25 IGLV3-19

2.84e-0469654M27108
PathwayREACTOME_SCAVENGING_OF_HEME_FROM_PLASMA

IGLV1-47 IGHV3-30 IGLV3-25 IGLV3-19

2.84e-0469654M27150
PathwayREACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS

IGLV1-47 IGHV3-30 IGLV3-25 IGLV3-19

3.17e-0471654M1078
PathwayREACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION

IGLV1-47 IGHV3-30 IGLV3-25 IGLV3-19

3.17e-0471654M27203
Pubmed

Molecular cloning, structural analysis, and expression of a human IRLB, MYC promoter-binding protein: new DENN domain-containing protein family emerges.

DENND4A DENND4B DENND4C

1.97e-08395312906859
Pubmed

SUV39H1 interacts with AML1 and abrogates AML1 transactivity. AML1 is methylated in vivo.

SUV39H1 RUNX1

7.38e-06295212917624
Pubmed

In triple negative breast tumor cells, PLC-β2 promotes the conversion of CD133high to CD133low phenotype and reduces the CD133-related invasiveness.

PROM1 PLCB2

7.38e-06295224330829
Pubmed

Identification and characterization of a sphingolipid delta 4-desaturase family.

DEGS2 DEGS1

7.38e-06295211937514
Pubmed

Dihydroceramide-based response to hypoxia.

DEGS2 DEGS1

7.38e-06295221914808
Pubmed

Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.

GTF2IRD2B GTF2IRD2

7.38e-06295215388857
Pubmed

Sequence and evolution of the human germline V lambda repertoire.

IGLV1-47 IGLV9-49 IGLV3-25 IGLV3-16

1.01e-05499548951372
Pubmed

One-megabase sequence analysis of the human immunoglobulin lambda gene locus.

IGLV1-47 IGLV9-49 IGLV3-25 IGLV3-19 IGLV3-16

1.28e-051099559074928
Pubmed

The FUSE binding proteins FBP1 and FBP3 are potential c-myc regulators in renal, but not in prostate and bladder cancer.

FUBP1 FUBP3

2.21e-05395219087307
Pubmed

The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia.

NBEA LRBA

2.21e-05395228814779
Pubmed

The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators.

FUBP1 FUBP3

2.21e-0539528940189
Pubmed

Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.

GTF2IRD2B GTF2IRD2

2.21e-05395215100712
Pubmed

Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation.

FUBP1 RUNX1

2.21e-05395230500954
Pubmed

Risk of cerebral venous thrombosis and novel gene polymorphisms of the coagulation and fibrinolytic systems.

TAF1 F5

4.41e-05495216155788
Pubmed

TFII-I gene family during tooth development: candidate genes for tooth anomalies in Williams syndrome.

GTF2IRD2B GTF2IRD2

4.41e-05495217823943
Pubmed

Evolution of general transcription factors.

GTF2IRD2B GTF2IRD2

4.41e-05495223229069
Pubmed

GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.

GTF2IRD2B GTF2IRD2

4.41e-05495222899722
Pubmed

The chaperone BAG6 captures dislocated glycoproteins in the cytosol.

RPN1 TRA

4.41e-05495224594942
Pubmed

Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions.

GTF2IRD2B GTF2IRD2

4.41e-05495221328569
Pubmed

Risk factors and genetics of atrial fibrillation.

SCN5A PITX2

7.34e-05595225443231
Pubmed

MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2.

RUNX1 KAT6B

7.34e-05595211965546
Pubmed

BCL8 is a novel, evolutionarily conserved human gene family encoding proteins with presumptive protein kinase A anchoring function.

NBEA LRBA

7.34e-05595212160729
Pubmed

RUNX1 associates with histone deacetylases and SUV39H1 to repress transcription.

SUV39H1 RUNX1

7.34e-05595216652147
Pubmed

Animal models of lysosomal disease: an overview.

HEXA GALC

1.10e-0469529728334
Pubmed

An evolutionarily conserved nested gene pair - Mab21 and Lrba/Nbea in metazoan.

NBEA LRBA

1.10e-04695219482073
Pubmed

Comparison of the human immune response to conjugate and polysaccharide pneumococcal vaccination using a reconstituted SCID mouse model.

IGHV3-30 IGKV2-29

1.10e-04695216860443
Pubmed

Mouse beta-mannosidase: cDNA cloning, expression, and chromosomal localization.

FUBP1 PITX2

1.10e-04695211892998
Pubmed

Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models.

SCN5A TTC21B

1.10e-04695224700869
Pubmed

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

DENND4A DENND4B DENND4C

1.43e-043795320937701
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH12 DNAH2

1.54e-0479529256245
Pubmed

Identification of differentially expressed genes associated with HER-2/neu overexpression in human breast cancer cells.

FOXRED1 RBM5

1.54e-04795210497265
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

MMP24 CEACAM21 FUBP1 SUV39H1 PPA2 DNAH2 PLCB2 TAF1 KAT6B

1.77e-0473095934857952
Pubmed

Axis development and early asymmetry in mammals.

HEXA PITX2

2.62e-0499529988215
Pubmed

Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening.

CDK16 LMTK3

3.28e-041095225495526
Pubmed

The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1-RUNX1T1.

RUNX1 TRIM5

4.00e-041195228536267
Pubmed

MTORC1-mediated NRBF2 phosphorylation functions as a switch for the class III PtdIns3K and autophagy.

RPTOR ATG14

4.00e-041195228059666
Pubmed

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

ANAPC1 NBEA LRBA RUNX1

4.43e-0412995423022380
Pubmed

Trisomy 21 Alters DNA Methylation in Parent-of-Origin-Dependent and -Independent Manners.

RUNX1 BACE2

4.79e-041295227100087
Pubmed

New nomenclature for chromatin-modifying enzymes.

SUV39H1 TAF1 KAT6B

5.19e-045795318022353
Pubmed

Chromosome mapping of the mouse Akt2 gene and Akt2 pseudogene.

GALK1 CEACAM21

5.65e-04139528976376
Pubmed

Identification of the genes regulated by Wnt-4, a critical signal for commitment of the ovary.

PITX2 RUNX1

6.58e-041495225645944
Pubmed

The biochemical anatomy of cortical inhibitory synapses.

GABRG1 NBEA

6.58e-041495222768092
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH12 DNAH2

6.58e-04149529373155
Pubmed

Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.

LMTK3 WAC

6.58e-041495228263302
Pubmed

STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum.

RPTOR ATG14

7.57e-041595229056340
Pubmed

Huntingtin interacts with a family of WW domain proteins.

PRPF40B ZDHHC17

7.57e-04159529700202
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

FOXK2 GALK1 TCERG1 GLRX3 FUBP1 FUBP3

8.09e-0439995635987950
Pubmed

PITX2 insufficiency leads to atrial electrical and structural remodeling linked to arrhythmogenesis.

SCN5A PITX2

1.10e-031895221511879
Pubmed

Misexpression of Tbx18 in cardiac chambers of fetal mice interferes with chamber-specific developmental programs but does not induce a pacemaker-like gene signature.

SCN5A PITX2

1.10e-031895227180262
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

DENND4A GALK1 NBEA LRBA PLBD2

1.13e-0328595534369648
Pubmed

Transcriptional fates of human-specific segmental duplications in brain.

GTF2IRD2B GTF2IRD2

1.22e-031995230228200
Pubmed

TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition.

ATG14 TRIM5

1.36e-032095225127057
Pubmed

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

RPN1 FUBP1 LRBA FUBP3 DENND4C

1.38e-0329895530737378
Pubmed

Hereditary Dystonia Overview

GALC CP TAF1

1.50e-038295320301334
Pubmed

Report of the sixth international workshop on human chromosome 3 mapping 1995.

SLC6A6 SCN5A

1.50e-03219528641130
Pubmed

Hierarchical Specification of Pruriceptors by Runt-Domain Transcription Factor Runx1.

IL31RA RUNX1

1.50e-032195228476948
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

PRSS3 GALK1 RPN1 GLRX3 PPA2 CP LRBA NMT1

1.67e-0380795830575818
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

GTF2IRD2B PRPF40B FUBP1 AOC2 PPA2 RBM5 PLBD2 TRIM5 DENND4C WAC

1.80e-031215951015146197
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

GABRG1 GTF2IRD2B DENND4A FOXRED1 RPN1 FUBP1 DNAH2 GTF2IRD2 RBM5 ZDHHC17 FUBP3

1.93e-031442951135575683
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

HEXA PRSS3 THBS2 GALC TCERG1 RPN1 PPA2 CP ZDHHC17 PLBD2 DEGS1

2.02e-031451951130550785
Pubmed

Genomic evolution of the placenta using co-option and duplication and divergence.

GALK1 CEACAM21

2.30e-032695218340042
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

TCERG1 RPN1 TAF1 FUBP3

2.37e-0320395422083510
Pubmed

A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.

PRSS3 DENND4A ATG14 NBEA

2.46e-0320595412040188
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

FOXK2 FUBP1 RPTOR ANKAR EHF TTC21B RBM5 LRBA KAT6B FBXO21 PLBD2

2.47e-031489951128611215
Pubmed

Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses.

NBEA LRBA

2.48e-032795219723784
Pubmed

Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil.

DEGS2 DEGS1

2.48e-032795225269881
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

FOXK2 FUBP1 RPTOR NMT1 DENND4C WAC

2.61e-0350395616964243
Pubmed

Chromatin regulation by BAF170 controls cerebral cortical size and thickness.

PROM1 PHF10

2.66e-032895223643363
Pubmed

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

PRMT8 FUBP1 RBM5 FUBP3 TOP3A

2.67e-0334795516033648
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PRSS3 FOXRED1 TCERG1 NBEA TAF1 LRBA RUNX1 BACE2 TRIM5 WAC

2.69e-031285951035914814
Cytoband22q11.2

IGLV1-47 IGLV9-49 IGLV3-25 IGLV3-19 IGLV3-16

5.39e-0612095522q11.2
GeneFamilyImmunoglobulin lambda locus at 22q11.2

IGLV1-47 IGLV9-49 IGLV3-25 IGLV3-19 IGLV3-16

2.43e-0589705353
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND4A DENND4B DENND4C

1.20e-0425703504
GeneFamilyFatty acid desaturases

DEGS2 DEGS1

4.08e-048702553
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEA LRBA

5.23e-0497021230
GeneFamilyProteases, serine

PRSS3 PRSS37 TMPRSS4

1.87e-0363703738
GeneFamilyDyneins, axonemal

DNAH12 DNAH2

1.94e-0317702536
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

TAF1 KAT6B

1.94e-0317702486
GeneFamilyImmunoglobulin kappa locus at 2p11.2

IGKV6D-41 IGKV2D-29 IGKV2-29

4.09e-0383703351
CoexpressionHE_LIM_SUN_FETAL_LUNG_C1_PROXIMAL_SECRETORY_PROGENITORS_CELL

PROM1 EHF TMPRSS4 CP RUNX1 LMTK3

7.29e-06135906M45710
ToppCell367C-Lymphocytic-Plasma_cell-|367C / Donor, Lineage, Cell class and subclass (all cells)

AMPD1 IGLV1-47 IGHV3-30 ST6GAL1 IGKV2D-29 LMTK3 IGLV9-49 IGKV2-29 IGLV3-16

7.93e-11167939f2185eb72f0137136f6d71af2a70168fded6c940
ToppCell367C-Lymphocytic-Plasma_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

AMPD1 IGLV1-47 IGHV3-30 ST6GAL1 IGKV2D-29 LMTK3 IGLV9-49 IGKV2-29 IGLV3-16

7.93e-111679395e768cf24699893e05d1bcb1c92dba2336943a64
ToppCellControl-Lymphoid-B_Plasma|Control / Disease state, Lineage and Cell class

AMPD1 IGLV1-47 IGHV3-30 ST6GAL1 IGKV2D-29 IGLV9-49 IGKV2-29 IGLV3-25 IGLV3-16

1.03e-1017293961e33836b8cb0f347f3e699eb587a37073b6fa4c
ToppCellBiopsy_IPF-Immune-Plasma_cells|Biopsy_IPF / Sample group, Lineage and Cell type

AMPD1 IGLV1-47 IGHV3-30 ST6GAL1 IGLV9-49 IGKV2-29 IGLV3-25 IGLV3-19

8.34e-09196938a1b6a8000b86efcb07843998aa3a49bb1f54bcda
ToppCellnormal_Lung-B_lymphocytes-MALT_B_cells|normal_Lung / Location, Cell class and cell subclass

AMPD1 IGLV1-47 IGHV3-30 IGKV2D-29 IGKV2-29 IGLV3-25 IGLV3-19

4.43e-08159937fbd0131b66f4267f7b0d6c3ad874ad097b859074
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PROM1 EHF TMPRSS4 CP NBEA BACE2 SDK1

4.82e-081619372d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellmetastatic_Brain-B_lymphocytes-Plasma_cells|metastatic_Brain / Location, Cell class and cell subclass

AMPD1 IGLV1-47 IGHV3-30 ST6GAL1 IGKV2D-29 IGLV9-49 IGLV3-25

7.00e-0817093753634da9e9c72f6400639954c286c6e38ea5a188
ToppCellCOPD-Lymphoid-B_Plasma|World / Disease state, Lineage and Cell class

AMPD1 IGLV1-47 IGHV3-30 ST6GAL1 IGKV2D-29 IGKV2-29 IGLV3-25

8.54e-08175937d73ee324479172501481b54967a0f3bd870fcf3a
ToppCell(2)_Plasma_cells|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

AMPD1 IGLV1-47 IGHV3-30 ST6GAL1 IGKV2D-29 IGLV9-49 IGLV3-16

9.22e-08177937ed3c936bb69f9bc7291b4f6cde1d204078117c48
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PROM1 EHF TMPRSS4 CP NBEA BACE2 SDK1

9.22e-08177937779ba86f53650772755b52460be03f18bb204e55
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PROM1 EHF TMPRSS4 CP NBEA BACE2 SDK1

9.22e-081779370f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCellAdult-Epithelial-lung_goblet_cell|Adult / Lineage, Cell type, age group and donor

PROM1 EHF TMPRSS4 CP NBEA BACE2 SDK1

9.96e-081799371fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AMPD1 IGLV1-47 IGHV3-30 WDR87 ST6GAL1 IGLV3-25 IGLV3-19

1.03e-07180937e3877f6ef5f54ff689058b4c996ab1851822f871
ToppCellnormal_Lymph_Node-B_lymphocytes-Plasma_cells|normal_Lymph_Node / Location, Cell class and cell subclass

AMPD1 IGLV1-47 IGHV3-30 RPN1 LMTK3 IGLV3-25 IGLV3-19

1.07e-07181937949ac3b60e7fb5968da4c4e872965fb4e10f4a35
ToppCellcellseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

AMPD1 IGLV1-47 IGHV3-30 ST6GAL1 IGLV9-49 IGLV3-25 IGLV3-19

1.16e-071839375ab4aa0304b832f98fff89b6c24ad5b7dd014c11
ToppCellnormal_Pleural_Fluid-B_lymphocytes-MALT_B_cells|normal_Pleural_Fluid / Location, Cell class and cell subclass

AMPD1 IGKV2D-29 LMTK3 IGKV2-29 IGLV3-25 IGLV3-19 IGLV3-16

1.44e-0718993705e8fb483ebb9010cc54b39d78cca960c58c0f01
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AMPD1 IGLV1-47 IGHV3-30 IGKV2D-29 IGKV2-29 IGLV3-25 IGLV3-19

1.49e-0719093779ee6d10dfbb775da149a1104da5823cf63bbb46
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AMPD1 IGLV1-47 IGHV3-30 IGKV2D-29 IGKV2-29 IGLV3-25 IGLV3-19

1.49e-0719093718762ce78ed0b206ade19e1c8ff76a2647489f68
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

PROM1 EHF TMPRSS4 CP NBEA BACE2 SDK1

1.49e-0719093751ca9ef4df3220487152fcf684147730637c7cc1
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PROM1 DNAH12 CP ST6GAL1 NBEA DEGS2 SDK1

1.85e-07196937d9426eba69047166ffa8179f1654e011c1020328
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PROM1 DNAH12 CP ST6GAL1 NBEA DEGS2 SDK1

1.85e-071969377e19919eafd6ddf547dd4e8aa532a050e182c5cc
ToppCellCOVID_non-vent-Lymphocytic-Plasma_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

IGLV1-47 IGHV3-30 RPN1 ST6GAL1 IGLV3-25 IGLV3-19 IGLV3-16

1.91e-071979371e63879633f20646e44873ae6b662f6faf4806fd
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AMPD1 IGLV1-47 IGHV3-30 ST6GAL1 IGKV2-29 IGLV3-25 IGLV3-16

1.91e-071979379fe1b757f76c2d43d39aa9ac500eaba98723985c
ToppCellBL-critical-LOC-Epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PROM1 DNAH12 EHF TMPRSS4 CP NBEA DEGS2

1.98e-071989376218a25b94d5fa2c69880539adf9c63bfe52dcd3
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PROM1 EHF CP NBEA RUNX1 BACE2 SDK1

2.12e-07200937b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCellmetastatic_Lymph_Node-B_lymphocytes-Plasma_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

AMPD1 IGLV1-47 IGHV3-30 IGLV9-49 IGLV3-25 IGLV3-19

5.41e-071429365ba3a33c2ee20be8baaed97536ca6e9d1de6752f
ToppCell368C-Lymphocytic-Plasma_cell-|368C / Donor, Lineage, Cell class and subclass (all cells)

AMPD1 IGLV1-47 IGHV3-30 ST6GAL1 IGKV2D-29 IGKV2-29

1.17e-06162936c21a54310b239d999bbc9d8fb5e8fda16e0bc336
ToppCell368C-Lymphocytic-Plasma_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

AMPD1 IGLV1-47 IGHV3-30 ST6GAL1 IGKV2D-29 IGKV2-29

1.17e-06162936f945688815229c8386cbcbf46deee7df316fa8d3
ToppCell3'_v3-Lung-Lymphocytic_B_plasma-Plasma_cells|Lung / Manually curated celltypes from each tissue

AMPD1 IGLV1-47 IGHV3-30 IGKV2D-29 IGLV9-49 IGKV2-29

1.26e-061649363b6a32ba53d05f6818fe950ac426f489383b645a
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AMPD1 IGLV1-47 IGHV3-30 IGLV9-49 IGLV3-25 IGLV3-19

1.71e-061739360ca2169a275404118038c0489a48062879488765
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PROM1 EHF TMPRSS4 CP NBEA SDK1

1.71e-06173936464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

PROM1 EHF TMPRSS4 CP NBEA SDK1

1.77e-061749367d2f802f493f19a068e097b2909a9000e2160266
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AMPD1 IGLV1-47 IGHV3-30 IGLV9-49 IGLV3-25 IGLV3-19

2.15e-06180936cea079bc02e08c46600eed05ab9924ec90e1e3d3
ToppCellmetastatic_Lymph_Node-B_lymphocytes-Plasma_cells|B_lymphocytes / Location, Cell class and cell subclass

AMPD1 IGLV1-47 IGHV3-30 LMTK3 IGLV9-49 IGLV3-25

2.30e-0618293627d1688fdfc570cedd233aa7030bce7d9b604d42
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

PROM1 EHF TMPRSS4 CP NBEA SDK1

2.30e-061829363f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

PROM1 EHF TMPRSS4 CP NBEA SDK1

2.37e-06183936940cbe298e9c53b5622af09264586ed823d3141f
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AMPD1 IGLV1-47 IGHV3-30 IGKV2D-29 IGKV2-29 IGLV3-25

2.37e-06183936cf5c98f451a568308c52da5c926543dd4836c6b2
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AMPD1 IGLV1-47 IGHV3-30 IGLV9-49 IGLV3-25 IGLV3-19

2.45e-0618493615f2c10101ccc8ed059520fc082ee42593dff269
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AMPD1 IGLV1-47 IGHV3-30 IGLV9-49 IGLV3-25 IGLV3-19

2.45e-06184936a90a58d9e319afa1cd572e4c2f516fadc42f56e5
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AMPD1 IGLV1-47 IGHV3-30 IGKV2D-29 IGKV2-29 IGLV3-25

2.52e-061859366ec009e48e50471c28e914c402f500e56a88f8f2
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AMPD1 IGLV1-47 IGHV3-30 IGLV9-49 IGLV3-25 IGLV3-19

2.52e-061859360fff2608f507e019ebb69c27e58fd5be3b049bef
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AMPD1 IGLV1-47 IGHV3-30 IGLV9-49 IGLV3-25 IGLV3-19

2.52e-0618593679edc1eeb7b5b9123961ac3ecf398ee68d9dddb9
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AMPD1 IGLV1-47 IGHV3-30 IGKV2D-29 IGKV2-29 IGLV3-25

2.52e-06185936f49ad6401b2abd089e30eba245b11b5031ea2318
ToppCellcellseq-Epithelial-Epithelial_Glandular-SMG_Basal/Duct|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PROM1 EHF TMPRSS4 CP ST6GAL1 RUNX1

3.03e-0619193630e7cc5f7eadf90ab0900a73fdfe48f9a1adcbfb
ToppCellcellseq-Epithelial-Epithelial_Glandular-SMG_Basal/Duct-SMG_Basal/Duct|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PROM1 EHF TMPRSS4 CP ST6GAL1 RUNX1

3.03e-0619193641d2f5278f6d5f52a5bdf4f3df70969481c00162
ToppCellnormal_Lymph_Node-B_lymphocytes-Plasma_cells|B_lymphocytes / Location, Cell class and cell subclass

AMPD1 IGLV1-47 RPN1 LMTK3 IGLV3-25 IGLV3-19

3.13e-06192936119832d4aee29ddda2485fc3e5dcdaacf833cc30
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AMPD1 IGHV3-30 WDR87 IGLV9-49 IGLV3-19 IGLV3-16

3.42e-06195936f3f7f1a77a1edd2b50a8211c76fe289738eb04cf
ToppCell15-Trachea|15 / Age, Tissue, Lineage and Cell class

PROM1 DNAH12 EHF CP DEGS2 RUNX1

3.52e-06196936fd17403422cf95c24f6be1c2d78764bb352f7f2e
ToppCellCOVID_vent-Lymphocytic-Plasma_cell-IgM_Plasmablast|COVID_vent / Disease condition, Lineage, Cell class and subclass

IGLV1-47 IGHV3-30 RPN1 IGKV2D-29 IGLV3-25 IGLV3-19

3.52e-06196936026a06d8d2089806823e6f6453d3ede84ae93bc6
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AMPD1 IGLV1-47 IGHV3-30 ST6GAL1 IGKV2-29 IGLV3-19

3.63e-0619793688b29d205237f07a9a26cc15a1cf4ed4816a4c4b
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGLV1-47 IGHV3-30 ST6GAL1 IGKV2D-29 IGKV2-29 IGLV3-25

3.63e-0619793676465bb2408c7c75f694e8f7cf1a606b796afc3a
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CP ST6GAL1 NBEA IL1RL1 FBXO21 SDK1

3.63e-06197936d6c9da7a3a6d2bcb13e2fc6605c8a59e7fb121c5
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EHF TMPRSS4 CP ST6GAL1 DEGS2 LMTK3

3.63e-06197936ec08a971e8dd9ad69359896c60ad77ff8af08fd0
ToppCellBronchial_Brush-Epithelial|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

PROM1 DNAH12 EHF CP NBEA DEGS2

3.63e-06197936272c7f4e582ef57564450540242b0db766b78328
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CP ST6GAL1 NBEA IL1RL1 FBXO21 SDK1

3.63e-0619793680b05c8ad9c1edc5dea3236079372475431343fe
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PROM1 EHF TMPRSS4 CP NBEA SDK1

3.73e-06198936af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCellNS-critical-d_07-13|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PROM1 EHF TMPRSS4 CP NBEA BACE2

3.73e-06198936a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCell18-Airway|18 / Age, Tissue, Lineage and Cell class

PROM1 THBS2 DNAH12 EHF CP RUNX1

3.73e-061989363cdfcc6445858c3c54058bbd90b20b88b1771cca
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_cell-B_naive|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGLV1-47 IGHV3-30 ST6GAL1 IGKV2-29 IGLV3-25 IGLV3-19

3.73e-0619893679c690d21d3420d0bb1a3b3b4ea2c9aa3810a219
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_cell-B_naive|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGLV1-47 ST6GAL1 IGKV2D-29 IGLV9-49 IGKV2-29 IGLV3-25

3.84e-061999368e02d3a066e79e0f2024a10738e0ea070513ef19
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

PROM1 EHF TMPRSS4 CP NBEA BACE2

3.96e-06200936682960e28542a3d6c119047cd0131941932cfdea
ToppCellBAL-Severe-Epithelial|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH12 EHF TMPRSS4 CP LMTK3 BACE2

3.96e-062009360cc7ff7b6a4eb05d2370ec2f3b9dbfe8cb0699de
ToppCellBronchus_Control_(B.)-Epithelial-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

PROM1 DNAH12 EHF TMPRSS4 CP NBEA

3.96e-06200936f5bc7d30aa03dd0f95eb64255bd1a2543be8d327
ToppCellBAL-Severe-Epithelial-Epithelial|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH12 EHF TMPRSS4 CP LMTK3 BACE2

3.96e-06200936b9cede2e0939c6b60ce1aa16d7efaaae79354580
ToppCellBAL-Severe-Epithelial|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH12 EHF TMPRSS4 CP LMTK3 BACE2

3.96e-06200936b762bf6f432eac05a476f6e2ab4da27dd13a2317
ToppCellBAL-Severe-Epithelial-Epithelial|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH12 EHF TMPRSS4 CP LMTK3 BACE2

3.96e-062009364c63204e0d868dd4c11c1604a238624a3ad54485
ToppCellSevere_COVID-19-Epithelial|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

DNAH12 EHF TMPRSS4 CP LMTK3 BACE2

3.96e-0620093649910efb6d888c208cd50530b03af19f87070630
ToppCellPBMC-Mild-cDC_3|Mild / Compartment, Disease Groups and Clusters

MMP24 PRPF40B ANKAR EHF IL1RL1

2.03e-051589355fefab4831687cd8dd45f5cc84f681398069c3be
ToppCell10x5'-Lung-Lymphocytic_B-Naive_B_cells|Lung / Manually curated celltypes from each tissue

IGLV1-47 IGHV3-30 ST6GAL1 DEGS2 IGKV2-29

2.50e-051659351776e7db80d7cf6b449fa8635a111705a59231b4
ToppCellAdult-Epithelial-lung_goblet_cell-D122|Adult / Lineage, Cell type, age group and donor

PROM1 EHF TMPRSS4 CP SDK1

2.65e-051679356efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell3'_v3-Lung-Lymphocytic_B_plasma|Lung / Manually curated celltypes from each tissue

AMPD1 IGLV1-47 IGHV3-30 IGKV2D-29 IGKV2-29

2.80e-05169935a65853ff9f6489cc1617cbba0d03b392d23c1528
ToppCelltumor_Lung-B_lymphocytes-Plasma_cells|tumor_Lung / Location, Cell class and cell subclass

AMPD1 IGHV3-30 IGKV2D-29 IGLV9-49 IGLV3-16

2.80e-05169935b36b7632ce55fc7b6b8b66020563d360b3de6fd7
ToppCellClub_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

PROM1 CP NBEA LMTK3 BACE2

2.80e-0516993503b303af8a26c6ff196507fe24f5bd3d75d7b1af
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGLV1-47 IGHV3-30 IGKV2-29 IGLV3-19 IGLV3-16

3.14e-051739357e6bfe85f60834f317941b70d6e0dc3bd527d293
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A CAPN7 TMPRSS4 BACE2 DENND4C

3.22e-05174935f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SCN5A CP CSMD3 F5 SDK1

3.40e-0517693505ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EHF TMPRSS4 CP BACE2 SDK1

3.50e-05177935cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PROM1 EHF TMPRSS4 CP NBEA

3.50e-05177935a4c001a8e44142babf9f24dfe6f7b73a70b11b16
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EHF TMPRSS4 CP BACE2 SDK1

3.50e-05177935ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PROM1 EHF TMPRSS4 CP NBEA

3.50e-05177935363e07b0f347f3716d530a28ead854b98e27d37c
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-Pre-B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGLV1-47 IGKV2D-29 IGLV9-49 IGKV2-29 IGLV3-19

3.59e-0517893534ef4d36ddfb1cdeaaaf5d952e1ad6dc2785ce1e
ToppCellASK454-Epithelial-Ciliated|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

PROM1 GTF2IRD2B PRMT8 DNAH12 TMEM232

3.69e-05179935f21919ef9d3d984e2925ef3d24f89e20fe265dcd
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PRMT8 EHF TMPRSS4 CP NBEA

3.79e-05180935b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellBAL-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGHV3-30 ST6GAL1 IGLV3-25 IGLV3-19 IGLV3-16

3.79e-051809356a777a308fa3160d31eda468db930e71862020b2
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AMPD1 IGLV1-47 IGHV3-30 IGLV9-49 IGLV3-25

3.99e-051829351bf2e4fd6222b41a7d08df6dcc500c9401db8c18
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_progenitors|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

EHF TMPRSS4 CP DEGS2 LMTK3

4.21e-05184935fcb5dd4fb3fa79f3b6029fad32a474cacde35a3b
ToppCellIPF-Myeloid-Mast|IPF / Disease state, Lineage and Cell class

PROM1 DENND4A GALC IL1RL1 BACE2

4.21e-05184935c3baf21f10b45cf91ac99997a59f353bcf3de8b7
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

PRSS3 EHF TMPRSS4 CP BACE2

4.21e-05184935d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-B_cells-Pre-B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGLV1-47 IGHV3-30 IGLV9-49 IGLV3-25 IGLV3-16

4.32e-051859350fa7970709dc957dea95fabbd83263a0335babd5
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

PRMT8 EHF TMPRSS4 CP SDK1

4.32e-05185935cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellCOPD-Epithelial-Goblet|World / Disease state, Lineage and Cell class

EHF TMPRSS4 CP BACE2 SDK1

4.43e-05186935d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCell10x5'-Lung-Mast|Lung / Manually curated celltypes from each tissue

PROM1 GALC NBEA IL1RL1 BACE2

4.54e-05187935f8ac5ca5cbe9c6f3d8c0fffc20fe08ca1aea43c0
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EHF DEGS2 RUNX1 ADTRP BACE2

4.54e-0518793574112df9b34051ae5cd2427ccfa3399eccff0076
ToppCellfacs-Bladder|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEXA EHF PITX2 DEGS2 BACE2

4.54e-05187935dd5ca59417fd1b388fd975f0f3e1f3245d66ebc5
ToppCell10x5'-Lung-Mast-Mast_cells|Lung / Manually curated celltypes from each tissue

PROM1 GALC NBEA IL1RL1 BACE2

4.54e-05187935da275d2c774b3e6a8ed77f777dd0676ecf2ddd2c
ToppCellCiliated_cells-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

PROM1 DNAH12 TMEM232 CP NBEA

4.54e-051879356fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCellfacs-Lung-EPCAM-24m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EHF DEGS2 RUNX1 ADTRP BACE2

4.54e-05187935214ce9b55fd6ce2fe7bd4cf4b1383517f5f0d759
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-B_lymphocytic|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

AMPD1 IGLV1-47 IGHV3-30 ST6GAL1 IGLV3-19

4.66e-05188935c3cae529fdbeb233d2b32bcc3537a8aba26a7dc2
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EHF TMPRSS4 CP ST6GAL1 BACE2

4.66e-051889355901b276f2379abf486b8285957277e95f08464e
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

PROM1 EHF TMPRSS4 CP NBEA

4.78e-0518993584d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
DrugCisapride [81098-60-4]; Down 200; 8.6uM; HL60; HT_HG-U133A

GALK1 PITX2 PLCB2 RUNX1 ZDHHC17 ADTRP F5 TOP3A

6.51e-071968482443_DN
Diseaseleft ventricular structural measurement

THBS2 TMEM232 RUNX1 KAT6B

1.24e-0488854EFO_0008205
Diseaseneuroticism measurement, wellbeing measurement, depressive symptom measurement

ADTRP SDK1

1.36e-0319852EFO_0007006, EFO_0007660, EFO_0007869
DiseaseATRIAL FIBRILLATION, FAMILIAL, 1 (disorder)

SCN5A PITX2

1.82e-0322852C1843687
Diseasedrug-induced liver injury

ST6GAL1 LRBA

2.17e-0324852EFO_0004228
Diseasemyeloproliferative disorder

RPN1 RUNX1

2.36e-0325852EFO_0004251
Diseaseuterine fibroid

GABRG1 DNAH2 FUBP3 TOP3A

2.65e-03199854EFO_0000731
Diseasecognitive function measurement

THBS2 DENND4A TMEM232 PRPF40B PPA2 TTC21B NBEA ADTRP BACE2 CSMD3 SDK1

2.70e-0314348511EFO_0008354

Protein segments in the cluster

PeptideGeneStartEntry
TDSSSTYLYWYKQEP

TRAV5

46

A0A0B4J249
TYLYWYKQEPGAGLQ

TRAV5

51

A0A0B4J249
QYCKGLYLWYTGEPN

TTC21B

1026

Q7Z4L5
GDIWYTPIKEEWYYQ

BACE2

261

Q9Y5Z0
PDDVFAQNYIWKGSY

CSMD3

3491

Q7Z407
CISPYSGKNTQIWYY

CRYBG3

2866

Q68DQ2
PNNGDYSAYYSWVEE

ATG14

271

Q6ZNE5
EHLFYESYQKSYPWE

ABCA9

881

Q8IUA7
NLYSYGWYKGKTVEP

CEACAM21

61

Q3KPI0
WYTFLNYYISQEGKD

ADTRP

16

Q96IZ2
PYTHWKQTVFYLEDY

PRMT8

331

Q9NR22
QEWTLEKNPSYTYYA

AMPD1

531

P23109
ITYGYYNKAVLESTW

DENND4A

846

Q7Z401
GKYEIQTWYSSPYPQ

KAT6B

726

Q8WYB5
HSDGKTYLYWYLQKP

IGKV2D-29

51

A0A075B6S2
CSGEALPKKYAYWYQ

IGLV3-16

41

A0A075B6K0
GYWLTNAIKYNQDYL

ANKAR

266

Q7Z5J8
YALLEVTYKGTQWYE

ANAPC1

1631

Q9H1A4
PWAYYSTVDQVKDLY

CP

876

P00450
SVGNYDYIWDFVLYP

AOC2

461

O75106
KHYSPTDYVNWLEEY

FBXO21

86

O94952
CSGDALPKQYAYWYQ

IGLV3-25

41

P01717
GQNWLKSYGYLLPYD

MMP24

81

Q9Y5R2
WVAVISYDGSNKYYA

IGHV3-30-5

66

P0DP03
DGNLQYYLYNWKCPS

NMT1

471

P30419
EKTLGYNIWYYPESN

IL31RA

261

Q8NI17
YNIWYYPESNTNLTE

IL31RA

266

Q8NI17
PAGQVDYTKAWEEYY

FUBP1

576

Q96AE4
NYPYYRTADKGWQNS

FOXK2

291

Q01167
YSNWPTYPQLYVKGE

GLRX3

296

O76003
WVAVISYDGSNKYYA

IGHV3-30-3

66

P0DP02
SEGIGNYLYWYQQKP

IGKV6D-41

46

A0A0C4DH26
LKLPYADYWYDILQS

LMTK3

376

Q96Q04
NYVYWYQQLPGTAPK

IGLV1-47

51

P01700
GYSNYKVDWYQQRPG

IGLV9-49

46

A0A0B4J1Y8
SSQPNYSKAWEDYYK

FUBP3

511

Q96I24
WANYVKGVIQYYPAA

GALK1

106

P51570
YETYVEKYNWLLDGT

DNAH12

411

Q6ZR08
LKYYYWAVNPQDRSG

LRBA

621

P50851
GIYTNVYKYVSWIEN

PRSS37

216

A4D1T9
LTQQYLYWDGEKETY

RBM5

491

P52756
PYGKYQETLIVWYEA

PPP4R3C

61

Q6ZMV5
FSYYPAENLIEYKWP

PHF10

66

Q8WUB8
KPSYTVDWYYSQTNK

IL1RL1

41

Q01638
DLCQYYDVIYLSWNP

CAPN7

526

Q9Y6W3
FSSYGYPKNEIEYKW

GABRG1

206

Q8N1C3
WPGILSNEEFKTYNY

CDK16

386

Q00536
NTWKDENYLYDTNYG

EHF

141

Q9NZC4
LKVQSAWAGYYDYNT

FOXRED1

401

Q96CU9
AEYYDNLPHYNSWIK

DEGS1

281

O15121
ETYSYYGPLNWITFN

DEGS2

241

Q6QHC5
ITYGYYNKVVLESPW

DENND4C

856

Q5VZ89
WVAVISYDGSNKYYA

IGHV3-30

66

P01768
YGYYNKAVLESKWPS

DENND4B

851

O75064
HSDGKTYLYWYLQKP

IGKV2-29

51

A2NJV5
QYGSLLYYTEIKWLS

GTF2IRD2

701

Q86UP8
QYGSLLYYTEIKWLS

GTF2IRD2B

701

Q6EKJ0
GSYPDWGSNYYQVKL

FLAD1

311

Q8NFF5
AWNLVASYYEQLPYG

GALC

306

P54803
YTDYADLGWKPYVQS

DNAH2

2226

Q9P225
GYKIYYWEADSQNET

SDK1

1736

Q7Z5N4
YLNRISYGPDWKDFY

HEXA

421

P06865
PWSYDQSYQYLGSIA

RUNX1

251

Q01196
TYNKTYVYPNWAIGL

SLC6A6

531

P31641
QPGETYTYKWNILEF

F5

476

P12259
LRSYYASWYQQKPGQ

IGLV3-19

46

P01714
VKDPWNLSNDEYYYP

TAF1

561

P21675
TLKYYYWVINPADSS

NBEA

646

Q8NFP9
FYVYEPLEYWNSSVQ

PTCHD4

521

Q6ZW05
PYLLNEDWEYYLSGK

PROM1

531

O43490
WKTHYIVGYNLPSYE

RPN1

326

P04843
SRGYEEQPQWEYNLY

SCN5A

1431

Q14524
VYHSDIPKWYQNPDY

ST6GAL1

261

P15907
YYYNCRTEVSQWEKP

WAC

146

Q9BTA9
YPGYSYNNWAAKGLT

PITX2

171

Q99697
NIFPYKGYIWNYGTL

PPA2

131

Q9H2U2
EQEYYLVKWRGYPDS

SUV39H1

56

O43463
YTQYIPLSIYDLQTW

RPTOR

171

Q8N122
PEGEKLVNYYSCSYW

TBC1D9B

151

Q66K14
PLIYSYIQDVYWNVG

PIGV

301

Q9NUD9
ENYQPKYGYWVIGLE

TRIM5

391

Q9C035
YRGYNEPDDYSTQWN

TSPAN16

131

Q9UKR8
LEPYNKKLGTDTWYY

TTC30B

571

Q8N4P2
LNSQVIYPESYYWTT

SLFN12L

531

Q6IEE8
YYYNNRTLESTWEKP

TCERG1

446

O14776
DTSESDYYLFWYKQP

TRA

46

P0DTU3
WTGYYGLVYNLVKIS

TMEM232

431

C9JQI7
WDPILGYINEQYEQY

SEPTIN12

126

Q8IYM1
PGVYTKVSAYLNWIY

TMPRSS4

416

Q9NRS4
GRIYYYNADDKQSVW

PRPF40B

106

Q6NWY9
DPKGYYLYWTYQSKE

PLCB2

41

Q00722
NYLDVYPYDHWSDKI

TOP3A

476

Q13472
YQYGYLAKPDTSFWI

nan

106

Q8IYB0
YSTWDIVKATQYGIY

ZDHHC17

56

Q8IUH5
NRPGVYTKVYNYVDW

PRSS3

281

P35030
LEPYNKKLGTDTWYY

TTC30A

571

Q86WT1
DTSESDYYLFWYKQP

TRAV38-2DV8

46

A0JD32
ELYQKTYWASYNIPS

PLBD2

416

Q8NHP8
TQTYWEDQPTRAYGY

THBS2

1046

P35442
TSWDGLNPYQILRYY

WDR87

756

Q6ZQQ6