Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	scaffold protein binding	DSP CASP8 GRID2 CHRFAM7A CHRNA7	1.87e-05	93	70	5	GO:0097110
GeneOntologyMolecularFunction	acetylcholine receptor activity	CHRFAM7A CHRM5 CHRNA7	6.95e-05	23	70	3	GO:0015464
GeneOntologyMolecularFunction	postsynaptic neurotransmitter receptor activity	GRID2 CHRFAM7A CHRM5 CHRNA7	1.40e-04	75	70	4	GO:0098960
GeneOntologyMolecularFunction	extracellular ligand-gated monoatomic ion channel activity	GRID2 CHRFAM7A CHRM5 CHRNA7	1.55e-04	77	70	4	GO:0005230
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	EFEMP1 GPR65 OR2T27 GPR35 OR11H7 OR2T7 OR1D5 GRID2 OR4K5 OR1D4 CHRFAM7A NPFFR1 CHRM5 CHRNA7	2.15e-04	1353	70	14	GO:0004888
GeneOntologyMolecularFunction	neurotransmitter receptor activity	GRID2 CHRFAM7A CHRM5 CHRNA7	4.21e-04	100	70	4	GO:0030594
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC5A5 ATP6V1A ATP6V1B1 COX7A2L GRID2 CACHD1 CHRFAM7A CNGA1 CHRM5 CHRNA7	4.23e-04	793	70	10	GO:0015075
GeneOntologyMolecularFunction	excitatory extracellular ligand-gated monoatomic ion channel activity	CHRFAM7A CHRM5 CHRNA7	4.60e-04	43	70	3	GO:0005231
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	GRID2 CHRFAM7A CNGA1 CHRM5 CHRNA7	5.83e-04	193	70	5	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	GRID2 CHRFAM7A CNGA1 CHRM5 CHRNA7	6.39e-04	197	70	5	GO:0022834
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC5A5 ATP6V1A ATP6V1B1 SLC22A14 SLC35A1 COX7A2L GRID2 CACHD1 CHRFAM7A CNGA1 CHRM5 CHRNA7	7.55e-04	1180	70	12	GO:0022857
GeneOntologyMolecularFunction	acetylcholine binding	CHRFAM7A CHRNA7	9.22e-04	13	70	2	GO:0042166
GeneOntologyMolecularFunction	G protein-coupled receptor activity	GPR65 OR2T27 GPR35 OR11H7 OR2T7 OR1D5 OR4K5 OR1D4 NPFFR1 CHRM5	9.79e-04	884	70	10	GO:0004930
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GRID2 CHRFAM7A CHRNA7	1.05e-03	57	70	3	GO:1904315
GeneOntologyMolecularFunction	monoatomic ion channel activity	ATP6V1A GRID2 CACHD1 CHRFAM7A CNGA1 CHRM5 CHRNA7	1.11e-03	459	70	7	GO:0005216
GeneOntologyMolecularFunction	gated channel activity	GRID2 CACHD1 CHRFAM7A CNGA1 CHRM5 CHRNA7	1.12e-03	334	70	6	GO:0022836
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	GRID2 CHRFAM7A CHRNA7	1.22e-03	60	70	3	GO:0099529
GeneOntologyMolecularFunction	chloride channel regulator activity	CHRFAM7A CHRNA7	1.24e-03	15	70	2	GO:0017081
GeneOntologyMolecularFunction	nuclease activity	ERN1 RPP30 ERN2 REXO1 TEFM	1.30e-03	231	70	5	GO:0004518
GeneOntologyMolecularFunction	endonuclease activity	ERN1 RPP30 ERN2 TEFM	1.33e-03	136	70	4	GO:0004519
GeneOntologyMolecularFunction	adenylate cyclase binding	CHRFAM7A CHRNA7	1.41e-03	16	70	2	GO:0008179
GeneOntologyMolecularFunction	transmitter-gated channel activity	GRID2 CHRFAM7A CHRNA7	1.54e-03	65	70	3	GO:0022835
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity	GRID2 CHRFAM7A CHRNA7	1.54e-03	65	70	3	GO:0022824
GeneOntologyMolecularFunction	acetylcholine-gated monoatomic cation-selective channel activity	CHRFAM7A CHRNA7	1.59e-03	17	70	2	GO:0022848
GeneOntologyMolecularFunction	transporter activity	SLC5A5 ATP6V1A ATP6V1B1 SLC22A14 SLC35A1 COX7A2L GRID2 CACHD1 CHRFAM7A CNGA1 CHRM5 CHRNA7	1.62e-03	1289	70	12	GO:0005215
GeneOntologyMolecularFunction	toxic substance binding	CHRFAM7A CHRNA7	1.79e-03	18	70	2	GO:0015643
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC5A5 ATP6V1A ATP6V1B1 COX7A2L CACHD1 CHRFAM7A CNGA1 CHRNA7	2.20e-03	664	70	8	GO:0008324
GeneOntologyMolecularFunction	channel activity	ATP6V1A GRID2 CACHD1 CHRFAM7A CNGA1 CHRM5 CHRNA7	2.39e-03	525	70	7	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	ATP6V1A GRID2 CACHD1 CHRFAM7A CNGA1 CHRM5 CHRNA7	2.42e-03	526	70	7	GO:0022803
GeneOntologyMolecularFunction	RNA endonuclease activity	ERN1 RPP30 ERN2	2.70e-03	79	70	3	GO:0004521
GeneOntologyMolecularFunction	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	ATP6V1A ATP6V1B1	3.18e-03	24	70	2	GO:0044769
GeneOntologyMolecularFunction	proton-transporting ATPase activity, rotational mechanism	ATP6V1A ATP6V1B1	3.18e-03	24	70	2	GO:0046961
GeneOntologyMolecularFunction	ATPase-coupled ion transmembrane transporter activity	ATP6V1A ATP6V1B1	3.18e-03	24	70	2	GO:0042625
GeneOntologyMolecularFunction	olfactory receptor activity	OR2T27 OR11H7 OR2T7 OR1D5 OR4K5 OR1D4	4.00e-03	431	70	6	GO:0004984
GeneOntologyMolecularFunction	phosphoric diester hydrolase activity	PDE1B SMPD4 CHRM5	4.81e-03	97	70	3	GO:0008081
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC5A5 ATP6V1A ATP6V1B1 COX7A2L CACHD1 CNGA1 CHRM5 CHRNA7	4.92e-03	758	70	8	GO:0015318
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC5A5 ATP6V1A ATP6V1B1 COX7A2L CACHD1 CNGA1 CHRNA7	6.31e-03	627	70	7	GO:0022890
GeneOntologyMolecularFunction	ATPase binding	ADCY10 CHRFAM7A CHRNA7	6.48e-03	108	70	3	GO:0051117
GeneOntologyBiologicalProcess	sensory perception	ATP6V1B1 EFEMP1 HMCN1 OR2T27 OR11H7 OR2T7 OR1D5 OR4K5 NDP WDR1 OR1D4 CHRFAM7A PKHD1L1 CNGA1 CHRNA7	1.99e-06	1072	69	15	GO:0007600
GeneOntologyBiologicalProcess	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	CHRFAM7A CHRNA7	1.10e-05	2	69	2	GO:0001988
GeneOntologyBiologicalProcess	baroreceptor response to decreased systemic arterial blood pressure	CHRFAM7A CHRNA7	3.30e-05	3	69	2	GO:0001982
GeneOntologyBiologicalProcess	generation of ovulation cycle rhythm	CHRFAM7A CHRNA7	6.59e-05	4	69	2	GO:0060112
GeneOntologyBiologicalProcess	regulation of membrane potential	ADCY10 DSP GPR35 GRID2 NDP WDR1 CHRFAM7A CNGA1 CHRNA7	9.86e-05	559	69	9	GO:0042391
GeneOntologyBiologicalProcess	sensory processing	CHRFAM7A CHRNA7	1.10e-04	5	69	2	GO:0050893
GeneOntologyBiologicalProcess	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback	CHRFAM7A CHRNA7	1.64e-04	6	69	2	GO:0001978
GeneOntologyCellularComponent	spine apparatus membrane	CHRFAM7A CHRNA7	3.31e-05	3	70	2	GO:0098897
GeneOntologyCellularComponent	IRE1-TRAF2-ASK1 complex	ERN1 ERN2	6.60e-05	4	70	2	GO:1990604
GeneOntologyCellularComponent	transmembrane transporter complex	ATP6V1A ATP6V1B1 COX7A2L GRID2 CACHD1 CHRFAM7A CNGA1 CHRNA7	3.52e-04	523	70	8	GO:1902495
GeneOntologyCellularComponent	spine apparatus	CHRFAM7A CHRNA7	3.92e-04	9	70	2	GO:0097444
GeneOntologyCellularComponent	transporter complex	ATP6V1A ATP6V1B1 COX7A2L GRID2 CACHD1 CHRFAM7A CNGA1 CHRNA7	4.92e-04	550	70	8	GO:1990351
GeneOntologyCellularComponent	vacuolar proton-transporting V-type ATPase, V1 domain	ATP6V1A ATP6V1B1	7.14e-04	12	70	2	GO:0000221
GeneOntologyCellularComponent	proton-transporting V-type ATPase, V1 domain	ATP6V1A ATP6V1B1	7.14e-04	12	70	2	GO:0033180
GeneOntologyCellularComponent	membrane protein complex	ATP6V1A ATP6V1B1 SCAP ERN1 AP1G1 CASP8 COX7A2L GRID2 CACHD1 ERN2 CHRFAM7A CNGA1 CHRNA7	1.27e-03	1498	70	13	GO:0098796
GeneOntologyCellularComponent	growth cone	ADCY10 ALS2 CHRFAM7A PCDH9 CHRNA7	1.38e-03	245	70	5	GO:0030426
GeneOntologyCellularComponent	site of polarized growth	ADCY10 ALS2 CHRFAM7A PCDH9 CHRNA7	1.59e-03	253	70	5	GO:0030427
GeneOntologyCellularComponent	acetylcholine-gated channel complex	CHRFAM7A CHRNA7	1.63e-03	18	70	2	GO:0005892
GeneOntologyCellularComponent	proton-transporting two-sector ATPase complex, catalytic domain	ATP6V1A ATP6V1B1	1.82e-03	19	70	2	GO:0033178
GeneOntologyCellularComponent	glycinergic synapse	CHRFAM7A CHRNA7	2.02e-03	20	70	2	GO:0098690
GeneOntologyCellularComponent	axolemma	CHRFAM7A CHRNA7	2.23e-03	21	70	2	GO:0030673
GeneOntologyCellularComponent	cholinergic synapse	CHRFAM7A CHRNA7	2.45e-03	22	70	2	GO:0098981
GeneOntologyCellularComponent	Golgi membrane	ATP6V1A SCAP B4GAT1 AP1G1 SLC35A1 SMPD4 HUWE1 RAB14	2.76e-03	721	70	8	GO:0000139
GeneOntologyCellularComponent	transport vesicle membrane	ATP6V1A ATP6V1B1 SCAP AP1G1 RAB14	3.01e-03	293	70	5	GO:0030658
GeneOntologyCellularComponent	extrinsic component of synaptic vesicle membrane	ATP6V1A ATP6V1B1	3.15e-03	25	70	2	GO:0098850
GeneOntologyCellularComponent	distal axon	ADCY10 ALS2 CHRFAM7A CNGA1 PCDH9 CHRNA7	3.35e-03	435	70	6	GO:0150034
GeneOntologyCellularComponent	vacuolar proton-transporting V-type ATPase complex	ATP6V1A ATP6V1B1	3.41e-03	26	70	2	GO:0016471
MousePheno	kinked sperm flagellum	ADCY10 AP1G1 SLC22A14 DNAH8 QRICH2	2.81e-06	56	56	5	MP:0009237
MousePheno	airway basal cell hyperplasia	CHRFAM7A CHRNA7	1.58e-05	2	56	2	MP:0011115
MousePheno	abnormal airway basal cell differentiation	CHRFAM7A CHRNA7	1.58e-05	2	56	2	MP:0011114
MousePheno	abnormal airway basal cell morphology	CHRFAM7A CHRNA7	1.58e-05	2	56	2	MP:0011113
MousePheno	head tilt	ATP6V1B1 AP1G1 GRID2 CACHD1	2.78e-05	44	56	4	MP:0005191
MousePheno	abnormal GABA-mediated receptor currents	GRID2 CHRFAM7A CHRNA7	4.76e-05	18	56	3	MP:0004008
MousePheno	impaired sperm capacitation	ADCY10 UBE3A SLC22A14	5.64e-05	19	56	3	MP:0003666
MousePheno	abnormal sperm capacitation	ADCY10 UBE3A SLC22A14	8.88e-05	22	56	3	MP:0013286
MousePheno	abnormal nicotine-mediated receptor currents	CHRFAM7A CHRNA7	9.41e-05	4	56	2	MP:0009475
MousePheno	abnormal cochlear endolymph ionic homeostasis	ATP6V1B1 CACHD1	1.56e-04	5	56	2	MP:0006403
MousePheno	abnormal sperm motility	ADCY10 AP1G1 SLC22A14 GRID2 CHRFAM7A DNAH8 QRICH2 CHRNA7	1.82e-04	401	56	8	MP:0002674
MousePheno	abnormal type I spiral ligament fibrocytes	ATP6V1B1 NDP	2.34e-04	6	56	2	MP:0004293
MousePheno	failure of neuromuscular synapse presynaptic differentiation	CHRFAM7A CHRNA7	2.34e-04	6	56	2	MP:0001054
MousePheno	whitened brown adipose tissue morphology	COX7A2L PLAC8	3.27e-04	7	56	2	MP:0020520
MousePheno	abnormal CNS synapse formation	GRID2 CHRFAM7A CHRNA7	3.64e-04	35	56	3	MP:0004996
MousePheno	decreased cochlear outer hair cell number	ATP6V1B1 AP1G1 CACHD1	3.64e-04	35	56	3	MP:0004402
MousePheno	abnormal sperm physiology	ADCY10 AP1G1 SLC22A14 GRID2 CHRFAM7A DNAH8 QRICH2 CHRNA7	3.79e-04	447	56	8	MP:0004543
MousePheno	abnormal neuron number	ATP6V1B1 AP1G1 ALS2 GRID2 NDP CACHD1 NPFFR1 PCDH9	4.33e-04	456	56	8	MP:0008946
MousePheno	abnormal GABAergic neuron physiology	CHRFAM7A CHRNA7	4.35e-04	8	56	2	MP:0011987
MousePheno	asthenozoospermia	ADCY10 AP1G1 SLC22A14 CHRFAM7A DNAH8 QRICH2 CHRNA7	5.74e-04	362	56	7	MP:0002675
Domain	Ribonuc_2-5A	ERN1 ERN2	3.79e-05	3	67	2	PF06479
Domain	KEN	ERN1 ERN2	3.79e-05	3	67	2	PS51392
Domain	KEN_dom	ERN1 ERN2	3.79e-05	3	67	2	IPR010513
Domain	PQQ	ERN1 ERN2	3.79e-05	3	67	2	PF01011
Domain	HECT	ITCH UBE3A HUWE1	1.21e-04	27	67	3	PF00632
Domain	HECTc	ITCH UBE3A HUWE1	1.21e-04	27	67	3	SM00119
Domain	HECT_dom	ITCH UBE3A HUWE1	1.21e-04	27	67	3	IPR000569
Domain	HECT	ITCH UBE3A HUWE1	1.21e-04	27	67	3	PS50237
Domain	PUG	ERN1 ERN2	1.26e-04	5	67	2	SM00580
Domain	ATP_synth_asu_C	ATP6V1A ATP6V1B1	1.26e-04	5	67	2	IPR000793
Domain	ATPase_a/bsu_AS	ATP6V1A ATP6V1B1	1.26e-04	5	67	2	IPR020003
Domain	ATP-synt_ab_N	ATP6V1A ATP6V1B1	1.26e-04	5	67	2	PF02874
Domain	ATP-synt_ab_C	ATP6V1A ATP6V1B1	1.26e-04	5	67	2	PF00306
Domain	ATPase_F1/V1/A1_a/bsu_N	ATP6V1A ATP6V1B1	1.26e-04	5	67	2	IPR004100
Domain	ATP-synt_ab	ATP6V1A ATP6V1B1	1.26e-04	5	67	2	PF00006
Domain	ATPASE_ALPHA_BETA	ATP6V1A ATP6V1B1	1.26e-04	5	67	2	PS00152
Domain	PQQ	ERN1 ERN2	1.88e-04	6	67	2	SM00564
Domain	PQQ_beta_propeller_repeat	ERN1 ERN2	1.88e-04	6	67	2	IPR018391
Domain	-	ERN1 ERN2	1.88e-04	6	67	2	2.140.10.10
Domain	Quinoprotein_ADH-like_fam	ERN1 ERN2	1.88e-04	6	67	2	IPR027295
Domain	PUB_domain	ERN1 ERN2	1.88e-04	6	67	2	IPR018997
Domain	PQQ_repeat	ERN1 ERN2	1.88e-04	6	67	2	IPR002372
Domain	ATPase_F1/V1/A1_a/bsu_nucl-bd	ATP6V1A ATP6V1B1	1.88e-04	6	67	2	IPR000194
Domain	GrpE_coiled_coil	DNAH8 CNGA1	8.18e-04	12	67	2	IPR013805
Domain	Quinoprotein_ADH-like_supfam	ERN1 WDR1 ERN2	9.09e-04	53	67	3	IPR011047
Domain	7tm_1	GPR65 OR2T27 GPR35 OR1D5 OR4K5 OR1D4 NPFFR1 CHRM5	2.83e-03	677	67	8	PF00001
Domain	G_PROTEIN_RECEP_F1_1	GPR65 OR2T27 GPR35 OR1D5 OR4K5 OR1D4 NPFFR1 CHRM5	3.04e-03	685	67	8	PS00237
Domain	-	CHRFAM7A CHRNA7	3.06e-03	23	67	2	1.20.120.370
Domain	Acetylcholine_rcpt_TM	CHRFAM7A CHRNA7	3.06e-03	23	67	2	IPR027361
Domain	G_PROTEIN_RECEP_F1_2	GPR65 OR2T27 GPR35 OR1D5 OR4K5 OR1D4 NPFFR1 CHRM5	3.21e-03	691	67	8	PS50262
Domain	GPCR_Rhodpsn	GPR65 OR2T27 GPR35 OR1D5 OR4K5 OR1D4 NPFFR1 CHRM5	3.24e-03	692	67	8	IPR000276
Domain	cEGF	EFEMP1 HMCN1	3.90e-03	26	67	2	IPR026823
Domain	cEGF	EFEMP1 HMCN1	3.90e-03	26	67	2	PF12662
Domain	GPCR_Rhodpsn_7TM	GPR65 OR2T27 GPR35 OR1D5 OR4K5 NPFFR1 CHRM5	1.00e-02	670	67	7	IPR017452
Pubmed	Vagus nerve stimulation promotes resolution of inflammation by a mechanism that involves Alox15 and requires the α7nAChR subunit.	CHRFAM7A CHRNA7 ALOX15	8.15e-09	3	71	3	35622894
Pubmed	Enhancing cognitive function in chronic TBI: The Role of α7 nicotinic acetylcholine receptor modulation.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	38070724
Pubmed	Inflammatory cytokines decrease the expression of nicotinic acetylcholine receptor during the cell maturation.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	19626424
Pubmed	Episodic memory performance predicted by the 2bp deletion in exon 6 of the "alpha 7-like" nicotinic receptor subunit gene.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	17012698
Pubmed	Cholinergic Pathway Suppresses Pulmonary Innate Immunity Facilitating Pneumonia After Stroke.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	26451017
Pubmed	Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	34453977
Pubmed	Perinatal hypoxia-ischemia reduces α 7 nicotinic receptor expression and selective α 7 nicotinic receptor stimulation suppresses inflammation and promotes microglial Mox phenotype.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	24757672
Pubmed	Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	26999808
Pubmed	Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	27129924
Pubmed	Neuroprotection afforded by nicotine against oxygen and glucose deprivation in hippocampal slices is lost in alpha7 nicotinic receptor knockout mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	17291692
Pubmed	Sensorimotor gating and spatial learning in α7-nicotinic receptor knockout mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	23521765
Pubmed	Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	28258105
Pubmed	The cholinergic anti-inflammatory system limits T cell infiltration into the neurodegenerative CNS, but cannot counteract complex CNS inflammation.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	19344760
Pubmed	Loss of α7nAChR enhances endothelial-to-mesenchymal transition after myocardial infarction via NF-κB activation.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	35926661
Pubmed	The alpha7 nicotinic receptor agonist 4OH-GTS-21 protects axotomized septohippocampal cholinergic neurons in wild type but not amyloid-overexpressing transgenic mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	17640819
Pubmed	Contribution of α7 nicotinic receptor to airway epithelium dysfunction under nicotine exposure.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	23431157
Pubmed	Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	29114104
Pubmed	Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	33995108
Pubmed	E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	32552811
Pubmed	Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	24836856
Pubmed	Modulation of the MAPKs pathways affects Aβ-induced cognitive deficits in Alzheimer's disease via activation of α7nAChR.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	31904546
Pubmed	Studies of sperm from mutant mice suggesting that two neurotransmitter receptors are important to the zona pellucida-initiated acrosome reaction.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	15948184
Pubmed	Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	35678315
Pubmed	Age-Associated Tooth Loss and Oral Microbial Dysbiosis in a Mouse Genetic Model of Chronic Nicotine Exposure.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	33117372
Pubmed	Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	12628457
Pubmed	Activation of α-7 nicotinic acetylcholine receptor reduces ischemic stroke injury through reduction of pro-inflammatory macrophages and oxidative stress.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	25157794
Pubmed	The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule.	ERN1 ERN2	4.11e-06	2	71	2	22315414
Pubmed	Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	19615981
Pubmed	Splenic nerve denervation attenuates depression-like behaviors in Chrna7 knock-out mice via the spleen-gut-brain axis.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	38944290
Pubmed	Nicotine withdrawal-induced inattention is absent in alpha7 nAChR knockout mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	28243714
Pubmed	Mesenchymal Stem Cells or Interleukin-6 Improve Episodic Memory of Mice Lacking α7 Nicotinic Acetylcholine Receptors.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	31202708
Pubmed	Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	22246862
Pubmed	Stimulation of the α7 nicotinic acetylcholine receptor protects against sepsis by inhibiting Toll-like receptor via phosphoinositide 3-kinase activation.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	24298024
Pubmed	Lung eosinophilia induced by house dust mites or ovalbumin is modulated by nicotinic receptor α7 and inhibited by cigarette smoke.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	29975102
Pubmed	α7-nAChR Knockout Mice Decreases Biliary Hyperplasia and Liver Fibrosis in Cholestatic Bile Duct-Ligated Mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	29580318
Pubmed	Alpha-7 Nicotinic Receptor Dampens Murine Osteoblastic Response to Inflammation and Age-Related Osteoarthritis.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	35479080
Pubmed	[Activation of α7 nAChR improves white fat homeostasis and promotes beige adipogenesis and thermogenesis in obese mice].	CHRFAM7A CHRNA7	4.11e-06	2	71	2	38597441
Pubmed	Activation of Nicotinic Acetylcholine Receptors Decreases Apoptosis in Human and Female Murine Pancreatic Islets.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	27471776
Pubmed	Targeting α-7 nicotinic acetylcholine receptor in the enteric nervous system: a cholinergic agonist prevents gut barrier failure after severe burn injury.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	22688057
Pubmed	α7 Nicotinic acetylcholine receptor agonist attenuates neuropathological changes associated with intracerebral hemorrhage in mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	22820264
Pubmed	Stimulation of α7-nAChRs coordinates autophagy and apoptosis signaling in experimental knee osteoarthritis.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	33953172
Pubmed	Different Effects of Nicotine and N-Stearoyl-ethanolamine on Episodic Memory and Brain Mitochondria of α7 Nicotinic Acetylcholine Receptor Knockout Mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	32028688
Pubmed	Genetic variation in CHRNA7 and CHRFAM7A is associated with nicotine dependence and response to varenicline treatment.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	30089821
Pubmed	Nicotinic acetylcholine receptor activation reduces skeletal muscle inflammation of mdx mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	20615555
Pubmed	Nicotine physical dependence in the mouse: involvement of the alpha7 nicotinic receptor subtype.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	15896732
Pubmed	Activation of α7 Nicotinic Acetylcholine Receptor Ameliorates Zymosan-Induced Acute Kidney Injury in BALB/c Mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	30429582
Pubmed	A transgenic mouse model reveals fast nicotinic transmission in hippocampal pyramidal neurons.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	21501254
Pubmed	α7-cholinergic receptor mediates vagal induction of splenic norepinephrine.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	21339364
Pubmed	Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	21368056
Pubmed	Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	24289814
Pubmed	Requisite role of the cholinergic alpha7 nicotinic acetylcholine receptor pathway in suppressing Gram-negative sepsis-induced acute lung inflammatory injury.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	19949071
Pubmed	Expression of human apolipoprotein A-II and its effect on high density lipoproteins in transgenic mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	1400473
Pubmed	Reversible inhibition of GABAA receptors by alpha7-containing nicotinic receptors on the vertebrate postsynaptic neurons.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	17204496
Pubmed	Activation of Alpha 7 Cholinergic Nicotinic Receptors Reduce Blood-Brain Barrier Permeability following Experimental Traumatic Brain Injury.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	26937017
Pubmed	α7 nicotinic receptors play a role in regulation of cardiac hemodynamics.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	37017608
Pubmed	Impaired hippocampal theta oscillations in the mice null alpha7 nicotinic acetylcholine receptors.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	23795917
Pubmed	Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stress.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	36603528
Pubmed	Endogenous signaling through alpha7-containing nicotinic receptors promotes maturation and integration of adult-born neurons in the hippocampus.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	20592195
Pubmed	Activation of α7nAChR Promotes Diabetic Wound Healing by Suppressing AGE-Induced TNF-α Production.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	26650489
Pubmed	Increased sensitivity to nicotine-induced seizures in mice expressing the L250T alpha 7 nicotinic acetylcholine receptor mutation.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	11854451
Pubmed	Lack of modulation of nicotinic acetylcholine alpha-7 receptor currents by kynurenic acid in adult hippocampal interneurons.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	22848433
Pubmed	Nicotine prevents synaptic impairment induced by amyloid-β oligomers through α7-nicotinic acetylcholine receptor activation.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	23842742
Pubmed	Abeta(1-42) modulation of Akt phosphorylation via alpha7 nAChR and NMDA receptors.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	17292512
Pubmed	Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	16650968
Pubmed	Microglial cell response in α7 nicotinic acetylcholine receptor-deficient mice after systemic infection with Escherichia coli.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	35413868
Pubmed	Circulating brain microvascular endothelial cells (cBMECs) as potential biomarkers of the blood-brain barrier disorders caused by microbial and non-microbial factors.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	23637989
Pubmed	Genomic organization and partial duplication of the human alpha7 neuronal nicotinic acetylcholine receptor gene (CHRNA7).	CHRFAM7A CHRNA7	4.11e-06	2	71	2	9782083
Pubmed	Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	24462939
Pubmed	Probing the putative α7 nAChR/NMDAR complex in human and murine cortex and hippocampus: Different degrees of complex formation in healthy and Alzheimer brain tissue.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	29261717
Pubmed	Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	18199426
Pubmed	Stroke-induced activation of the α7 nicotinic receptor increases Pseudomonas aeruginosa lung injury.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	22490926
Pubmed	Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	36997969
Pubmed	A phenotype for the alpha 7 nicotinic acetylcholine receptor null mutant.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	15364017
Pubmed	Choline, an alpha7 nicotinic acetylcholine receptor agonist, alleviates hyperalgesia in a rat osteoarthritis model.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	23769729
Pubmed	Mice deficient in CHRNA7, a subunit of the nicotinic acetylcholine receptor, produce sperm with impaired motility.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	15944242
Pubmed	Dendritic spine alterations in the hippocampus and parietal cortex of alpha7 nicotinic acetylcholine receptor knockout mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	23270857
Pubmed	Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	18077004
Pubmed	Smoking in adult attention-deficit/hyperactivity disorder: interaction between 15q13 nicotinic genes and Temperament Character Inventory scores.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	19462340
Pubmed	Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	16923147
Pubmed	NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	11790782
Pubmed	A role of the subdiaphragmatic vagus nerve in depression-like phenotypes in mice after fecal microbiota transplantation from Chrna7 knock-out mice with depression-like phenotypes.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	33422641
Pubmed	Nicotinic ACh receptor α7 inhibits PDGF-induced migration of vascular smooth muscle cells by activating mitochondrial deacetylase sirtuin 3.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	30270436
Pubmed	Activation of α-7 Nicotinic Acetylcholine Receptor Attenuates Cardiac Inflammation Through NLRP3/Caspase-1/IL-18 Pathway.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	34988776
Pubmed	Genetic deletion of α7 nAChRs reduces hippocampal granule and pyramidal cell number in both sexes but impairs pattern separation in males only.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	37746145
Pubmed	A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	19631623
Pubmed	Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	15770102
Pubmed	Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	24326163
Pubmed	Loss of α7 nicotinic acetylcholine receptors in GABAergic neurons causes sex-dependent decreases in radial glia-like cell quantity and impairments in cognitive and social behavior.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	33398432
Pubmed	Functional role of alpha7 nicotinic receptor in chronic neuropathic and inflammatory pain: studies in transgenic mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	23811428
Pubmed	beta-Amyloid activates presynaptic alpha7 nicotinic acetylcholine receptors reconstituted into a model nerve cell system: involvement of lipid rafts.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	20374280
Pubmed	Proteome profile of the cerebellum from α7 nicotinic acetylcholine receptor deficient mice.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	38185761
Pubmed	Alpha 7 subunit of nAChR regulates migration of human mesenchymal stem cells.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	20720594
Pubmed	α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	22624500
Pubmed	Involvement of acetylcholine-α7nAChR in the protective effects of arterial baroreflex against ischemic stroke.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	23106973
Pubmed	Suppression of neuroinflammation by an allosteric agonist and positive allosteric modulator of the α7 nicotinic acetylcholine receptor GAT107.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	33902624
Pubmed	Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	17019565
Pubmed	Dilinoleoylphosphatidylcholine ameliorates scopolamine-induced impairment of spatial learning and memory by targeting alpha7 nicotinic ACh receptors.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	19100751
Pubmed	Identification of an alternatively processed nicotinic receptor alpha7 subunit RNA in mouse brain.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	14499477
Pubmed	Multiple calcium channels and kinases mediate alpha7 nicotinic receptor neuroprotection in PC12 cells.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	15969741
Pubmed	Activation of the α7 Nicotinic Acetylcholine Receptor Prevents against Microglial-Induced Inflammation and Insulin Resistance in Hypothalamic Neuronal Cells.	CHRFAM7A CHRNA7	4.11e-06	2	71	2	35883638
Cytoband	17p13.3	OR1D5 OR1D4 ALOX15	3.69e-04	88	72	3	17p13.3
Cytoband	4p12	TEC CNGA1	4.52e-04	20	72	2	4p12
Cytoband	2p13.1	ATP6V1B1 STAMBP	1.32e-03	34	72	2	2p13.1
GeneFamily	Fibulins	EFEMP1 HMCN1	1.68e-04	8	45	2	556
GeneFamily	V-type ATPases	ATP6V1A ATP6V1B1	1.48e-03	23	45	2	415
Coexpression	GSE12198_CTRL_VS_HIGH_IL2_STIM_NK_CELL_UP	SLC5A5 GPR65 GPR35 DNAH8 PLAC8 MYORG	1.31e-05	199	68	6	M7067
Coexpression	GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_8H_DN	ATP6V1B1 EFEMP1 ALS2 DNAH8 PCDH9 PLAC8	1.31e-05	199	68	6	M8265
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC5A5 HMCN1 DSP ERN2 CHRM5 ALOX15	3.50e-07	171	72	6	121e63ca281ad765d76c2afb3b4d441329b47f81
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATP6V1B1 HMCN1 EXPH5 ADAMTS16 CACHD1 CHRFAM7A	4.29e-07	177	72	6	c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell	NS-moderate-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DSP EXPH5 CPLANE1 ERN2 PLAC8 ALOX15	8.76e-07	200	72	6	64462a18afca3c1a8548a857924b8166058bf958
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A5 KLHL11 EXPH5 ERN2 CNGA1	5.80e-06	158	72	5	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A5 KLHL11 EXPH5 ERN2 CNGA1	5.80e-06	158	72	5	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	Control-Lymphocytic_NKT-T_cells-T-cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPR65 DPEP2 CASP8 TEC PLAC8	1.03e-05	178	72	5	910f8bea19d335455aba24e6a07b4834b709db5d
ToppCell	Control-Lymphocytic_NKT-T_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPR65 DPEP2 CASP8 TEC PLAC8	1.06e-05	179	72	5	d892d9496f1c33e23312092591eb2e968e736f7d
ToppCell	Control-Lymphocytic_NKT\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPR65 DPEP2 CASP8 TEC PLAC8	1.25e-05	185	72	5	59d68e119f58b35bab36294758f6b2e25fd8f5c0
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	KLHL11 USP34 HUWE1 MED23 CPLANE1	1.53e-05	193	72	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW13\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	ATP6V1B1 EFEMP1 DSP CHRM5 PLAC8	1.61e-05	195	72	5	f760f2713417b01b64e42101652b8080581d643c
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATP6V1B1 EFEMP1 EXPH5 ADAMTS16 CACHD1	1.65e-05	196	72	5	f40d10ea7714067585493fdc89744714aa427de8
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATP6V1B1 EFEMP1 EXPH5 ADAMTS16 CACHD1	1.65e-05	196	72	5	b8350340d86e4524e9616a427e7f2e116a6fb3be
ToppCell	NS-critical-d_07-13\|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DSP EXPH5 CPLANE1 ERN2 ALOX15	1.73e-05	198	72	5	a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-DC3-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	UPF2 EXPH5 DPEP2 WDR1 PLAC8	1.77e-05	199	72	5	7271dbeca9aa838b88ad44d00059263a29c0316b
ToppCell	Bronchial_Biopsy-Epithelial\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	EFEMP1 DSP EXPH5 PLAC8 ALOX15	1.77e-05	199	72	5	ef5d8917c8d011184830a0b8197afc6266707b37
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HMCN1 CYP27C1 NPFFR1 QRICH2	8.06e-05	141	72	4	31e0984f09983e83a814424f74c871c1c5a3a789
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HMCN1 CYP27C1 NPFFR1 QRICH2	8.06e-05	141	72	4	d7d3c3932651d90fa4f3c4e3df16f4b677faaf9f
ToppCell	LPS-IL1RA-Hematopoietic_Mast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPR35 DPEP2 TEC ALOX15	8.28e-05	142	72	4	f7d0d5ca9fc3dd929d4fdd59b71bfa623007e992
ToppCell	LPS-IL1RA-Hematopoietic_Mast-Mast_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPR35 DPEP2 TEC ALOX15	8.28e-05	142	72	4	2a9a070e7c53ac593d46c6c5f6983f07d4413501
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D175\|Adult / Lineage, Cell type, age group and donor	HMCN1 ADAMTS16 CACHD1 PCDH9	9.72e-05	148	72	4	012845b10850bbc67814da247ee5a69f6d631eaa
ToppCell	Control-Lymphocytic_NKT-T_cells-iNKT-MAIT\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPR65 ERN1 DPEP2 TEC	1.05e-04	151	72	4	7e5e35ce601ca3d3722063566e89664909171b8d
ToppCell	facs-MAT-Fat-24m-Myeloid-macrophage\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR65 GPR35 DPEP2 ALOX15	1.16e-04	155	72	4	d0c1608f8f6b6f4174e51d610501c707cba5e015
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATP6V1B1 HMCN1 EXPH5 ADAMTS16	1.19e-04	156	72	4	4d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR65 GPR35 DPEP2 PLAC8	1.25e-04	158	72	4	ad1040bce6ad655c2502d9abb02507ecff177f83
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR65 GPR35 DPEP2 PLAC8	1.25e-04	158	72	4	ac7aef01eda1dca80d6c5b508649fcad55803a67
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADCY10 PPP2R2B PKHD1L1 CNGA1	1.38e-04	162	72	4	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(Neuron.Gad1Gad2.Sst-Nr2f2)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GPR35 ERN2 CHRM5	1.39e-04	62	72	3	9db88da996b9977f5a89afe505cd55e7b5324bc9
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(Neuron.Gad1Gad2.Sst-Nr2f2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GPR35 ERN2 CHRM5	1.39e-04	62	72	3	461d280a1b955033186cfc326f9ace85b4a53c54
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_TNFAIP8L3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DSP CYP27C1 CHRFAM7A CHRNA7	1.41e-04	163	72	4	7352c30c253f69f65dcb15f46f9c87719741b55b
ToppCell	Mild-MAIT\|World / Disease group and Cell class	GPR65 ATRIP ERN1 DSP	1.44e-04	164	72	4	21dc02997dfae73cf70ce291661928526605dba1
ToppCell	droplet-Lung-nan-18m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITCH GPR35 DPEP2 PLAC8	1.48e-04	165	72	4	e32697321cef424c2ad4e11ee9da3e510d5ce505
ToppCell	droplet-Lung-nan-18m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITCH GPR35 DPEP2 PLAC8	1.48e-04	165	72	4	0fbdd043e11aa8dbff4cd3a4da1b2feb49878a09
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GPR65 GPR35 DPEP2 PLAC8	1.55e-04	167	72	4	8aacb102c1b0067a86eb6c2acedd07667198487d
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PPP2R2B DSP NPFFR1 ALOX15	1.58e-04	168	72	4	e870d2e69316406f45112ed0bf324b24f902a99e
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PPP2R2B CYP27C1 POLR2F PCDH9	1.58e-04	168	72	4	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	droplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITCH GPR35 DPEP2 PLAC8	1.58e-04	168	72	4	00cff4698db14e03ca1d1b409e5ed1ad23b12615
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PPP2R2B DSP NPFFR1 ALOX15	1.58e-04	168	72	4	403aba73a0f9ffb32252288d075fad8a588ca440
ToppCell	droplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITCH GPR35 DPEP2 PLAC8	1.62e-04	169	72	4	90c00ab30e582b0e2a2be751e1fae9024cfb9ea6
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC5A5 ATP6V1B1 ERN2 ALOX15	1.62e-04	169	72	4	40b557549fe08c5dc9dba359af35993d68d1640a
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GPR65 GPR35 DPEP2 PLAC8	1.66e-04	170	72	4	a6f2a792980e6a1025b8f1b0eda442a555938488
ToppCell	LPS-IL1RA-Lymphocytic_NKT-T_cells-T-cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPEP2 CASP8 TEC PLAC8	1.69e-04	171	72	4	539ea88acc6f948efdeae8b69e5c5ffaee29f1d9
ToppCell	droplet-Heart-4Chambers-21m-Hematologic-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 GPR35 DPEP2 PLAC8	1.69e-04	171	72	4	e852d0e8589eecf4a2e5fea039b52a67c5d58dbd
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPR65 ERN1 TEC PCDH9	1.69e-04	171	72	4	6ab7f103cbdbd49ef687cbb8a42ddc5517af0f7f
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cel\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A5 ADAMTS16 NDP ALOX15	1.73e-04	172	72	4	c0bda7153e02bee7d0326138cc684151c404c2a1
ToppCell	LPS-IL1RA-Lymphocytic_NKT-T_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPEP2 CASP8 TEC PLAC8	1.73e-04	172	72	4	0fc692be845d4225ff8b63bf9195724fc8510c2c
ToppCell	Club-club-3\|World / Class top	ATP6V1B1 PKHD1L1 CNGA1 ALOX15	1.73e-04	172	72	4	34fbb82a2ec77dd183cf26b38edeb7e936b707bc
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PPP2R2B EFEMP1 SLC22A14 PKHD1L1	1.77e-04	173	72	4	ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL11 ALS2 ERN2 DNAH8	1.77e-04	173	72	4	8bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL11 ALS2 ERN2 DNAH8	1.77e-04	173	72	4	3e3c61468e703330788a10d850ef41a85680f86d
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PPP2R2B EFEMP1 SLC22A14 PKHD1L1	1.77e-04	173	72	4	3725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCell	10x5'-blood-Lymphocytic_Invariant-Inducer-like-MAIT\|blood / Manually curated celltypes from each tissue	PPP2R2B GPR65 ERN1 MAST1	1.85e-04	175	72	4	b4e4b66e89f79999768a6192c8404cb2465f920b
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXPH5 CNGA1 TEC ALOX15	1.89e-04	176	72	4	8e4600efeea095a92178cfd26d7c58db7dfc0c80
ToppCell	Club_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	HMCN1 DSP CYP27C1 ERN2	1.89e-04	176	72	4	88c4ed0ab4a4ede8cad21385d799b723b5786cd9
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPEP2 CASP8 TEC PLAC8	1.89e-04	176	72	4	ea27e18407b8a13e8212830da859efeb8f158690
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells-T-cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPEP2 CASP8 TEC PLAC8	1.89e-04	176	72	4	bfbab3c5b738b3b0b1540f2059d0245fbd8c0031
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PPP2R2B EFEMP1 SLC22A14 PKHD1L1	1.98e-04	178	72	4	1e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCell	wk_15-18-Mesenchymal-Mesothelial-intermediate_mesothelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	EFEMP1 GRID2 PKHD1L1 ALOX15	2.02e-04	179	72	4	b1f085e4c8d65d5cdbfaf2db80343638abb08979
ToppCell	LPS-antiTNF-Lymphocytic_NKT\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPEP2 CASP8 TEC PLAC8	2.02e-04	179	72	4	ecea75c568911ff56939c9f67ab901497bd4356c
ToppCell	LPS-IL1RA-Lymphocytic_NKT\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPEP2 CASP8 TEC PLAC8	2.02e-04	179	72	4	5ccf0824611ded5c673d94dff3048aedac12f1a8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HMCN1 EXPH5 ADAMTS16 CACHD1	2.02e-04	179	72	4	666072c0e8448dbaec1683d18368ec2502453f90
ToppCell	5'-Adult-SmallIntestine-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP2R2B HMCN1 CYP27C1 PCDH9	2.06e-04	180	72	4	5e6e38ee0758ef2342a6a821c78ed24b57bb7b11
ToppCell	LPS_only-Lymphocytic_NKT-T_cells-T-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPEP2 CASP8 TEC PLAC8	2.06e-04	180	72	4	dcef253f2e97e4436b1b04e8a06a53ff6e64522c
ToppCell	5'-Adult-SmallIntestine-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP2R2B HMCN1 CYP27C1 PCDH9	2.06e-04	180	72	4	b88cd7ae922782176c057342d1b9eb9b8e5e7204
ToppCell	5'-Adult-SmallIntestine-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP2R2B HMCN1 CYP27C1 PCDH9	2.06e-04	180	72	4	ebd6e719a03f25155fa8181be19469d04d6d10a6
ToppCell	LV-17._Lymphocyte\|LV / Chamber and Cluster_Paper	PPP2R2B ERN1 CASP8 PLAC8	2.11e-04	181	72	4	81fafa69c8c240250a667a5f3b321e8be1b9a288
ToppCell	LPS_only-Lymphocytic_NKT-T_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPEP2 CASP8 TEC PLAC8	2.11e-04	181	72	4	a4347ae554e6dcf03c7001a2b69332b377c7c034
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HMCN1 EXPH5 ADAMTS16 CACHD1	2.15e-04	182	72	4	5f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell	droplet-Liver-Npc-21m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A5 ATP6V1B1 NDP ALOX15	2.20e-04	183	72	4	99ab7a43527eb226027efbcd8c0b6a8e46fc3c93
ToppCell	droplet-Liver-Npc-21m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A5 ATP6V1B1 NDP ALOX15	2.20e-04	183	72	4	28916f0597690ff534578be2cb715b485cb1de1a
ToppCell	RA-17._Lymphocyte\|World / Chamber and Cluster_Paper	PPP2R2B ERN1 DPEP2 PLAC8	2.20e-04	183	72	4	6397f684a50346fc42cccb5afbe10350f4b2d9b0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HMCN1 EXPH5 ADAMTS16 CACHD1	2.20e-04	183	72	4	2e831a4d99c6f983793df71c0994124c943c6da9
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP6V1B1 ERN2 PLAC8 ALOX15	2.24e-04	184	72	4	c2ca984551baf4becbefbe58bd1889828542b045
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	EFEMP1 GRID2 PKHD1L1 ALOX15	2.29e-04	185	72	4	492529121cb9e88bd3c0db6b54af3cd2979572bc
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATP6V1B1 DSP EXPH5 ERN2	2.34e-04	186	72	4	37b93ebd64ebbd08193a746e5bc9b350c2570733
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 SLC22A14 PKHD1L1 ALOX15	2.38e-04	187	72	4	4e553721fa5598cb211f44e3226280b7e6885484
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 SLC22A14 PKHD1L1 ALOX15	2.38e-04	187	72	4	d36e7fc6125e7a4310499365022d38f34b757a73
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 SLC22A14 PKHD1L1 ALOX15	2.38e-04	187	72	4	827eae63fabf6892a82ce7779b5f395958d3d628
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATP6V1B1 DSP EXPH5 ERN2	2.43e-04	188	72	4	8ffb5394f7b00ea483a5fe4df894d22fda935e5c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HMCN1 EXPH5 ADAMTS16 CACHD1	2.43e-04	188	72	4	bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell	LPS_only-Lymphocytic_NKT\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPEP2 CASP8 TEC PLAC8	2.43e-04	188	72	4	bbe65b1c11c88ab62d8485cfc3a913ff9da89aad
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HMCN1 EXPH5 ADAMTS16 CACHD1	2.43e-04	188	72	4	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATP6V1B1 DSP EXPH5 ERN2	2.43e-04	188	72	4	137ed9958044fab7a13648affb469585d1c48cf6
ToppCell	Fetal_29-31_weeks-Immune-natural_killer_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PPP2R2B GPR65 ERN1 PLAC8	2.43e-04	188	72	4	1082861eb9e00409caa06d8b2a7b8e7f5fac94c9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HMCN1 EXPH5 ADAMTS16 CACHD1	2.48e-04	189	72	4	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HMCN1 EXPH5 ADAMTS16 CACHD1	2.48e-04	189	72	4	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	cellseq-Epithelial-Epithelial_Glandular-SMG_Basal/Duct\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ATP6V1B1 DSP ERN2 CNGA1	2.58e-04	191	72	4	30e7cc5f7eadf90ab0900a73fdfe48f9a1adcbfb
ToppCell	cellseq-Epithelial-Epithelial_Glandular-SMG_Basal/Duct-SMG_Basal/Duct\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ATP6V1B1 DSP ERN2 CNGA1	2.58e-04	191	72	4	41d2f5278f6d5f52a5bdf4f3df70969481c00162
ToppCell	ILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	EFEMP1 DSP DPEP2 PKHD1L1	2.64e-04	192	72	4	d43caf42ec744e895137f31ef65a990e250669d2
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ADCY10 EXPH5 PKHD1L1	2.64e-04	77	72	3	a799ccdb84014e978d9fbccf3d2fee8fbeac7b0c
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP6V1B1 EFEMP1 DSP EXPH5	2.69e-04	193	72	4	536b277d90070c4571c592a3c6323b4bf4819f67
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP6V1B1 EFEMP1 DSP EXPH5	2.69e-04	193	72	4	04d47ba7cc1f19f1ffb18d9e68469e75063697cf
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP6V1B1 EFEMP1 DSP EXPH5	2.69e-04	193	72	4	0499611c21d283321ef6dd24add154dea48da1b7
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EXPH5 CACHD1 CPLANE1 ALOX15	2.69e-04	193	72	4	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	Club_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	SLC5A5 DSP CYP27C1 ERN2	2.69e-04	193	72	4	6582c0367052b9d10fb629c383ee0c55872afd2d
ToppCell	Club_cells\|World / lung cells shred on cell class, cell subclass, sample id	SLC5A5 DSP CYP27C1 ERN2	2.69e-04	193	72	4	9d3165dc5763a07a7d873f497624d9d6528fa2db
ToppCell	BLOOD--(1)_MAIT-like_CD8_T_cells\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PPP2R2B GPR65 ERN1 SLC35A1	2.74e-04	194	72	4	0064bcd9ac2fecec81f8d4e7d9f86f0089872fe7
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSP EXPH5 NXPE1 ERN2	2.80e-04	195	72	4	c5f33b420c9ac14dc67fea632b8c2bc2442cbf3d
ToppCell	IPF-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	EFEMP1 HMCN1 DSP PKHD1L1	2.80e-04	195	72	4	de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCell	Epithelial_cells-Club_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	SLC5A5 DSP CYP27C1 ERN2	2.80e-04	195	72	4	b758676abfc4e6930b696d270ecc0ea461b87a54
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Duct\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ATP6V1B1 ATRIP NDP CNGA1	2.80e-04	195	72	4	fdbb4abc0c79a6aeace71bfa5a5c5576ca39d758
Disease	tyrosine-protein kinase TEC measurement	TEC TEC	3.13e-05	4	68	2	EFO_0020830
Disease	cognitive disorder (implicated_via_orthology)	CHRFAM7A CHRNA7	7.80e-05	6	68	2	DOID:1561 (implicated_via_orthology)
Disease	rheumatoid arthritis (biomarker_via_orthology)	CHRFAM7A CHRNA7	7.80e-05	6	68	2	DOID:7148 (biomarker_via_orthology)
Disease	nicotine dependence (implicated_via_orthology)	CHRFAM7A CHRNA7	3.40e-04	12	68	2	DOID:0050742 (implicated_via_orthology)
Disease	cystathionine measurement	TEC TEC	8.72e-04	19	68	2	EFO_0010474
Disease	Epilepsy, Cryptogenic	ERN1 UBE3A STAMBP	9.10e-04	82	68	3	C0086237
Disease	Awakening Epilepsy	ERN1 UBE3A STAMBP	9.10e-04	82	68	3	C0751111
Disease	Aura	ERN1 UBE3A STAMBP	9.10e-04	82	68	3	C0236018
Disease	orofacial cleft, sex interaction measurement	EXPH5 CHRFAM7A CHRNA7	1.04e-03	86	68	3	EFO_0008343, MONDO_0000358
Disease	diaphragmatic hernia	EFEMP1 ADAMTS16	1.07e-03	21	68	2	EFO_0008561
Disease	Ovarian Serous Adenocarcinoma	ERN1 MAST1	1.28e-03	23	68	2	C1335177
Disease	Disorder of eye	EFEMP1 NDP CPLANE1 CNGA1	1.47e-03	212	68	4	C0015397
Disease	Epilepsy	ERN1 UBE3A STAMBP	2.06e-03	109	68	3	C0014544
Disease	ceramide measurement	ATP6V1A TEC ERN2 TEC	2.14e-03	235	68	4	EFO_0010222

Protein segments in the cluster

Peptide	Gene	Start	Entry
HSGRYIMTRDYLTVK	PPP2R2B	291	Q00005
YSMEGVATILYESRL	CYP27C1	226	Q4G0S4
SGDYRVYRGLLKTTM	B4GAT1	76	O43505
LVETLVAVYRMTYVG	ALS2	1386	Q96Q42
LYYATSRGTDIRMAQ	ALG3	111	Q92685
MSSLNTYIVRRYIAT	CACHD1	721	Q5VU97
PRRTMTLTYYDGISR	ADCY10	1451	Q96PN6
ARSIRIYEMNVSTSY	ADAMTS16	771	Q8TE57
TFTVTMRRRTLYYGL	CHRNA7	221	P36544
GALMVYDITRRSTYN	RAB14	86	P61106
VTDMADYTYSTVPRR	QRICH2	1541	Q9H0J4
TIMRVLTTAGSYVRD	AP1G1	421	O43747
GMRRVYTTVLFSHIY	NPFFR1	211	Q9GZQ6
RLYIGRTQYTVTMHD	ERN2	156	Q76MJ5
FTTRYMDYSVGVLLR	GRID2	536	O43424
SGSYTRILITVYRMS	OR2T7	206	P0C7T2
YYVVIMSRRTCTVLV	OR4K5	131	Q8NGD3
ASYIYDLIRRTMETP	PCDH9	781	Q9HC56
ERMFRRTYTSVGPTY	PDE1B	136	Q01064
GVSRYYNTSERMTSL	DNAH8	271	Q96JB1
TYSRLLVYMEIESLG	MED23	566	Q9ULK4
MGLYRIRVSTGASLY	ALOX15	1	P16050
TSTIYDMYRTREPRV	EXPH5	291	Q8NEV8
GSYTRILITVYRMSE	OR2T27	216	Q8NH04
YMSISLVTAIAVDRY	GPR35	101	Q9HC97
FTAGRRRYTVQFTTM	HUWE1	1651	Q7Z6Z7
TFTVTMRRRTLYYGL	CHRFAM7A	131	Q494W8
LRAIRVYMGDTDVYS	MAST1	981	Q9Y2H9
GYVLYASAMTLLTER	SMPD4	846	Q9NXE4
VYTTRPLREAETYRM	HMCN1	5591	Q96RW7
MGRIYYVDHFTRTTT	ITCH	371	Q96J02
AVIEYMYTGRIRVST	KLHL11	156	Q9NVR0
YLVISDGYMVTTLRF	CPLANE1	411	Q9H799
TSLLYLGRTEYTITM	ERN1	151	O75460
GTSRMYYSRRGVITD	DSP	36	P15924
YRVMLYQISEEVSRS	CASP8	101	Q14790
LYRTTMALTVGGTIY	COX7A2L	86	O14548
SLSILRTFYMLGVRY	DPEP2	196	Q9H4A9
RTFYMLGVRYLTLTH	DPEP2	201	Q9H4A9
YMYITSRPDRVALET	ATRIP	636	Q8WXE1
VSYTYFTLSLRMREL	SLC22A14	391	Q9Y267
SGVSLYTRKRMVSYT	SCAP	221	Q12770
YTRKRMVSYTITLVF	SCAP	226	Q12770
TYMTTRNREVSYLTD	NXPE1	256	Q8N323
MVYILGSYTLVLRTV	OR11H7	211	Q8NGC8
YRMVESAVIFRTLYS	UPF2	881	Q9HAU5
LGFMTTSYVRIVRTI	OR1D4	211	P47884
LGFMTTSYVRIVRTI	OR1D5	211	P58170
TTVLTRAEGLKYYRM	PDHA2	51	P29803
YSPAIKDSTMRRYTI	RPP30	156	P78346
QSIVYKYMSIRSDRS	EFEMP1	391	Q12805
EMSYTTYGLELTRVT	REXO1	1066	Q8N1G1
TLMAAVYTIALRYTR	SLC35A1	21	P78382
MYTDLATIYERAGRV	ATP6V1B1	321	P15313
NYEVVTMVTRGHRLY	TEC	571	P42680
YLMKILTERGYRFTT	POTEJ	851	P0CG39
RITTPYMTKYERARV	POLR2F	51	P61218
SLMRGIYSSSVYLEE	TEFM	201	Q96QE5
DTVRYTSLMLRDYSG	WDR1	386	O75083
VSVMTILYCRIYRET	CHRM5	206	P08912
SRGRLSLYIQMSSVY	LINC00615	11	Q96LM1
VYLIDMFVRTRTGYL	CNGA1	206	P29973
MYSERRITVLYSLVQ	UBE3A	501	Q05086
RLGLTSTYEYLEMRF	SLC5A5	111	Q92911
YFRSGVEIIRMASIY	STAMBP	36	O95630
SIYTGITLSEYFRDM	ATP6V1A	326	P38606
YTRAMPEDSYTVRVS	PKHD1L1	101	Q86WI1
KRTYTMYRITVALTS	GPR65	266	Q8IYL9
SGGMRLTATYRYILS	NDP	111	Q00604
VKPSTRILSIMYYAR	TRMT6	161	Q9UJA5
TSVAMRTLYRTRYGI	PLAC8	66	Q9NZF1
GTSLIQRLMSVAYTY	USP34	1591	Q70CQ2
GSDVTSIHKYMVRRY	MYORG	286	Q6NSJ0