Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondisordered domain specific binding

CREBBP HSP90AA1 HSP90AB3P

6.00e-0539393GO:0097718
GeneOntologyMolecularFunctionATP-dependent protein folding chaperone

HSP90AA5P HSP90AA1 HSP90AB3P

6.47e-0540393GO:0140662
GeneOntologyMolecularFunctionATP hydrolysis activity

CHD9 ABCF1 HSP90AA5P DHX29 HSP90AA1 HSP90AB3P

1.97e-04441396GO:0016887
GeneOntologyMolecularFunctiontranslation activator activity

ABCF1 DHX29

3.84e-0415392GO:0008494
GeneOntologyMolecularFunctionprotein folding chaperone

HSP90AA5P HSP90AA1 HSP90AB3P

3.90e-0473393GO:0044183
GeneOntologyMolecularFunctiontranscription corepressor activity

TCERG1 CREBBP SAP18 HDAC1

1.01e-03229394GO:0003714
GeneOntologyMolecularFunctionATP-dependent activity

CHD9 ABCF1 HSP90AA5P DHX29 HSP90AA1 HSP90AB3P

1.13e-03614396GO:0140657
GeneOntologyMolecularFunctionRNA polymerase II general transcription initiation factor binding

ZNHIT6 CREBBP

1.27e-0327392GO:0001091
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

CNGB1 RYR1

1.89e-0333392GO:0005217
GeneOntologyMolecularFunctionunfolded protein binding

HSP90AA5P HSP90AA1 HSP90AB3P

1.90e-03126393GO:0051082
GeneOntologyMolecularFunctionchromatin binding

NAP1L3 POLR3D PBRM1 CREBBP HDAC1 MYBL1

2.89e-03739396GO:0003682
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

CHD9 ABCF1 HSP90AA5P DHX29 HSP90AA1 HSP90AB3P

3.66e-03775396GO:0017111
GeneOntologyMolecularFunctionhistone acetyltransferase activity

BAZ1A CREBBP

4.46e-0351392GO:0004402
GeneOntologyMolecularFunctionsodium channel activity

CNGB1 SCN4A

4.63e-0352392GO:0005272
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

BAZ1A CREBBP

5.17e-0355392GO:0061733
GeneOntologyMolecularFunctionpyrophosphatase activity

CHD9 ABCF1 HSP90AA5P DHX29 HSP90AA1 HSP90AB3P

5.39e-03839396GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

CHD9 ABCF1 HSP90AA5P DHX29 HSP90AA1 HSP90AB3P

5.42e-03840396GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

CHD9 ABCF1 HSP90AA5P DHX29 HSP90AA1 HSP90AB3P

5.42e-03840396GO:0016818
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

BAZ1A CREBBP

6.13e-0360392GO:0034212
GeneOntologyMolecularFunctionprotein domain specific binding

CREBBP RCC2 HSP90AA1 HDAC1 MYB HSP90AB3P

6.59e-03875396GO:0019904
GeneOntologyMolecularFunctiongeneral transcription initiation factor binding

ZNHIT6 CREBBP

6.94e-0364392GO:0140296
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

ZNHIT6 CREBBP

7.37e-0366392GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

ZNHIT6 CREBBP

7.37e-0366392GO:0001098
GeneOntologyMolecularFunctionp53 binding

CREBBP HDAC1

9.92e-0377392GO:0002039
GeneOntologyMolecularFunctionhistone modifying activity

BAZ1A CREBBP HDAC1

1.00e-02229393GO:0140993
GeneOntologyMolecularFunctionN-acetyltransferase activity

BAZ1A CREBBP

1.02e-0278392GO:0008080
GeneOntologyMolecularFunctionpromoter-specific chromatin binding

HDAC1 MYBL1

1.14e-0283392GO:1990841
GeneOntologyBiologicalProcessmRNA processing

SAFB2 SRRT UPF3B THOC2 TCERG1 CWC25 CWC27 SAP18 RBMX2 ZMAT2

5.40e-085513910GO:0006397
GeneOntologyBiologicalProcessRNA splicing

UPF3B THOC2 TCERG1 CWC25 CWC27 SAP18 RBMX2 ZMAT2

3.69e-06502398GO:0008380
GeneOntologyBiologicalProcessmRNA metabolic process

SAFB2 SRRT UPF3B THOC2 TCERG1 CWC25 CWC27 SAP18 RBMX2 ZMAT2

5.63e-069173910GO:0016071
GeneOntologyBiologicalProcessinterferon-beta production

POLR3D TRAF3IP1 CREBBP HSP90AA1

1.08e-0573394GO:0032608
GeneOntologyBiologicalProcessregulation of interferon-beta production

POLR3D TRAF3IP1 CREBBP HSP90AA1

1.08e-0573394GO:0032648
GeneOntologyBiologicalProcessmRNA splicing, via spliceosome

UPF3B CWC25 CWC27 SAP18 RBMX2 ZMAT2

5.27e-05358396GO:0000398
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions with bulged adenosine as nucleophile

UPF3B CWC25 CWC27 SAP18 RBMX2 ZMAT2

5.27e-05358396GO:0000377
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions

UPF3B CWC25 CWC27 SAP18 RBMX2 ZMAT2

5.61e-05362396GO:0000375
GeneOntologyBiologicalProcessRNA processing

SAFB2 SRRT UPF3B ZNHIT6 THOC2 TCERG1 CWC25 CWC27 SAP18 RBMX2 ZMAT2

7.26e-0515003911GO:0006396
GeneOntologyBiologicalProcessstem cell division

THOC2 GNL3 MYB

1.08e-0449393GO:0017145
GeneOntologyBiologicalProcessregulation of type I interferon production

POLR3D TRAF3IP1 CREBBP HSP90AA1

1.43e-04141394GO:0032479
GeneOntologyBiologicalProcessmanchette assembly

CFAP70 SPAG17

1.55e-0410392GO:1905198
GeneOntologyBiologicalProcesstype I interferon production

POLR3D TRAF3IP1 CREBBP HSP90AA1

1.59e-04145394GO:0032606
GeneOntologyBiologicalProcessembryonic digit morphogenesis

TRAF3IP1 CREBBP HDAC1

3.69e-0474393GO:0042733
GeneOntologyBiologicalProcesspositive regulation of DNA metabolic process

PBRM1 BAZ1A CREBBP GNL3 HSP90AA1

3.90e-04333395GO:0051054
GeneOntologyBiologicalProcesschromatin remodeling

NAP1L3 CHD9 PBRM1 BAZ1A CREBBP HDAC1 MYBL1

4.23e-04741397GO:0006338
GeneOntologyBiologicalProcesscellular response to heat

CREBBP HSP90AA1 HSP90AB3P

4.82e-0481393GO:0034605
GeneOntologyBiologicalProcessnegative regulation of interferon-beta production

TRAF3IP1 CREBBP

6.48e-0420392GO:0032688
GeneOntologyCellularComponentnuclear protein-containing complex

UPF3B POLR3D PBRM1 THOC2 CWC25 BAZ1A CWC27 CREBBP SAP18 RBMX2 ZMAT2 HDAC1 MYB

6.70e-0713773913GO:0140513
GeneOntologyCellularComponentU2-type spliceosomal complex

CWC25 CWC27 RBMX2 ZMAT2

3.16e-0597394GO:0005684
GeneOntologyCellularComponentU2-type precatalytic spliceosome

CWC27 RBMX2 ZMAT2

1.18e-0451393GO:0071005
GeneOntologyCellularComponentprecatalytic spliceosome

CWC27 RBMX2 ZMAT2

1.39e-0454393GO:0071011
GeneOntologyCellularComponentnuclear body

SAFB2 SRRT THOC2 TCERG1 CWC25 CREBBP SAP18 GNL3

2.19e-04903398GO:0016604
GeneOntologyCellularComponentspliceosomal complex

CWC25 CWC27 RBMX2 ZMAT2

6.75e-04215394GO:0005681
GeneOntologyCellularComponentexon-exon junction complex

UPF3B SAP18

6.96e-0421392GO:0035145
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

PBRM1 BAZ1A HDAC1

7.61e-0496393GO:0070603
GeneOntologyCellularComponentchromosomal region

PBRM1 THOC2 BAZ1A CREBBP RCC2

1.06e-03421395GO:0098687
GeneOntologyCellularComponentmanchette

CFAP70 SPAG17

1.24e-0328392GO:0002177
GeneOntologyCellularComponentchromosome, centromeric region

PBRM1 BAZ1A CREBBP RCC2

1.70e-03276394GO:0000775
GeneOntologyCellularComponentATPase complex

PBRM1 BAZ1A HDAC1

1.78e-03129393GO:1904949
GeneOntologyCellularComponentnuclear matrix

PBRM1 TCERG1 MYB

2.25e-03140393GO:0016363
DomainTscrpt_reg_Wos2-domain

MYB MYBL1

3.61e-062362IPR012642
DomainLMSTEN

MYB MYBL1

3.61e-062362PF07988
DomainC-myb_C

MYB MYBL1

1.08e-053362IPR015395
DomainCmyb_C

MYB MYBL1

1.08e-053362PF09316
DomainBromodomain_CS

PBRM1 BAZ1A CREBBP

1.66e-0526363IPR018359
DomainBROMODOMAIN_1

PBRM1 BAZ1A CREBBP

4.88e-0537363PS00633
DomainBromodomain

PBRM1 BAZ1A CREBBP

5.30e-0538363PF00439
DomainBROMODOMAIN_2

PBRM1 BAZ1A CREBBP

6.67e-0541363PS50014
DomainBROMO

PBRM1 BAZ1A CREBBP

7.17e-0542363SM00297
DomainBromodomain

PBRM1 BAZ1A CREBBP

7.17e-0542363IPR001487
Domain-

PBRM1 BAZ1A CREBBP

7.17e-05423631.20.920.10
DomainHTH_MYB

MYB MYBL1

1.29e-049362PS51294
DomainMyb_dom

MYB MYBL1

1.29e-049362IPR017930
DomainIon_trans_dom

CNGB1 RYR1 SCN4A

1.37e-03114363IPR005821
DomainIon_trans

CNGB1 RYR1 SCN4A

1.37e-03114363PF00520
DomainNucleotide-bd_a/b_plait

SAFB2 SRRT UPF3B RBMX2

1.48e-03258364IPR012677
DomainMyb_DNA-binding

MYB MYBL1

2.07e-0335362PF00249
DomainMYB_LIKE

MYB MYBL1

2.43e-0338362PS50090
DomainSANT

MYB MYBL1

4.18e-0350362SM00717
DomainSANT/Myb

MYB MYBL1

4.51e-0352362IPR001005
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

SRRT UPF3B THOC2 TCERG1 CWC25 CWC27 SAP18 RBMX2 ZMAT2

6.39e-09283319M13087
PathwayREACTOME_MRNA_SPLICING

SRRT UPF3B TCERG1 CWC25 CWC27 SAP18 RBMX2 ZMAT2

1.34e-08212318M14033
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

SRRT UPF3B THOC2 TCERG1 CWC25 CWC27 RBMX2 ZMAT2

1.07e-07277318MM15414
PathwayREACTOME_MRNA_SPLICING

SRRT UPF3B TCERG1 CWC25 CWC27 RBMX2 ZMAT2

2.12e-07201317MM15411
PathwayREACTOME_METABOLISM_OF_RNA

SRRT UPF3B THOC2 TCERG1 CWC25 CWC27 SAP18 GNL3 RBMX2 ZMAT2

1.99e-067243110M16843
PathwayREACTOME_METABOLISM_OF_RNA

SRRT UPF3B THOC2 TCERG1 CWC25 CWC27 GNL3 RBMX2 ZMAT2

4.41e-06612319MM15547
PathwayPID_HEDGEHOG_GLI_PATHWAY

CREBBP SAP18 HDAC1

1.56e-0448313M219
PathwayPID_HES_HEY_PATHWAY

CREBBP HDAC1 MYB

1.56e-0448313M288
PathwayPID_AR_TF_PATHWAY

CREBBP HSP90AA1 HDAC1

2.09e-0453313M151
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

CREBBP HSP90AA1 HDAC1 MYB

3.02e-04149314M27888
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

CREBBP MYB MYBL1

3.84e-0465313M39682
PathwayPID_HDAC_CLASSI_PATHWAY

CREBBP SAP18 HDAC1

4.01e-0466313M101
PathwayPID_TELOMERASE_PATHWAY

SAP18 HSP90AA1 HDAC1

4.19e-0467313M105
PathwayREACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE

CHD9 TRAF3IP1 CNGB1 CREBBP HSP90AA1

4.35e-04297315M27050
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP HDAC1

5.51e-0416312M8516
PathwayPID_MYC_ACTIV_PATHWAY

POLR3D CREBBP HSP90AA1

6.80e-0479313M66
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

CHD9 CREBBP

7.01e-0418312M26942
PathwayPID_REG_GR_PATHWAY

CREBBP HSP90AA1 HDAC1

7.58e-0482313M115
PathwayPID_SMAD2_3NUCLEAR_PATHWAY

CREBBP SAP18 HDAC1

7.58e-0482313M2
PathwayWP_HEDGEHOG_SIGNALING_PATHWAY

CREBBP SAP18

1.05e-0322312MM15924
PathwayWP_CILIARY_LANDSCAPE

TBC1D4 TRAF3IP1 CREBBP HDAC1

1.20e-03215314M39734
PathwayBIOCARTA_WNT_PATHWAY

CREBBP HDAC1

1.25e-0324312M16517
PathwayBIOCARTA_VDR_PATHWAY

CREBBP HDAC1

1.25e-0324312M13404
PathwayREACTOME_ESR_MEDIATED_SIGNALING

CREBBP HSP90AA1 HDAC1 MYB

1.30e-03220314M27794
PathwayWP_IL6_SIGNALING_PATHWAY

CREBBP HSP90AA1 HDAC1

1.35e-03100313MM15826
PathwayBIOCARTA_CARM_ER_PATHWAY

CREBBP HDAC1

1.47e-0326312M2499
PathwayREACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION

CHD9 CREBBP

1.59e-0327312M26943
PathwayREACTOME_ATTENUATION_PHASE

CREBBP HSP90AA1

1.71e-0328312M27254
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

CREBBP HDAC1

1.71e-0328312M6177
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

PBRM1 CREBBP HDAC1 MYB

1.72e-03237314M27786
PathwayREACTOME_ADIPOGENESIS

CHD9 CREBBP HDAC1

1.77e-03110313M48259
PathwayREACTOME_PIWI_INTERACTING_RNA_PIRNA_BIOGENESIS

HSP90AA1 MYBL1

1.83e-0329312M27462
PathwayPID_RETINOIC_ACID_PATHWAY

CREBBP HDAC1

1.96e-0330312M207
PathwayWP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR

CREBBP HDAC1

2.23e-0332312M39521
PathwayPID_IL2_PI3K_PATHWAY

HSP90AA1 MYB

2.51e-0334312M143
PathwayPID_PI3KCI_AKT_PATHWAY

TBC1D4 HSP90AA1

2.66e-0335312M249
PathwayKEGG_SPLICEOSOME

THOC2 TCERG1 ZMAT2

2.67e-03127313M2044
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

PBRM1 CREBBP SAP18 HDAC1

2.83e-03272314M29619
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

SAFB2 SRRT UPF3B ABCF1 PBRM1 THOC2 TCERG1 DHX29 BAZ1A RCC2 GNL3 HDAC1

2.44e-11759391235915203
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

SAFB2 SRRT CHD9 POLR3D PBRM1 THOC2 TCERG1 BAZ1A CREBBP SAP18 GNL3 HSP90AA1 HDAC1

4.10e-111014391332416067
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

SAFB2 UPF3B ABCF1 ZNHIT6 THOC2 TCERG1 HSP90AA5P RCC2 GNL3 RBMX2 HSP90AA1 HDAC1

3.16e-10949391236574265
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

SAFB2 SRRT ABCF1 THOC2 TCERG1 BAZ1A CWC27 SAP18 RCC2 HDAC1

2.19e-09660391032780723
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

SAFB2 UPF3B ABCF1 THOC2 TCERG1 DHX29 BAZ1A RCC2 GNL3 ZMAT2 HSP90AA1

4.17e-09934391133916271
Pubmed

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

SAFB2 SRRT THOC2 TCERG1 SAP18 RCC2 GNL3 RBMX2 ZMAT2 HSP90AA1

5.80e-09731391029298432
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

CHD9 ABCF1 PBRM1 THOC2 TCERG1 BAZ1A SAP18 GNL3 HDAC1

6.14e-0953339930554943
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

SAFB2 SRRT UPF3B ABCF1 TCERG1 DHX29 SAP18 RCC2 GNL3 HSP90AA1

1.48e-08807391022681889
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

SAFB2 CHD9 UPF3B ABCF1 THOC2 TCERG1 CREBBP RCC2 ZMAT2 HDAC1 MYB

2.31e-081103391134189442
Pubmed

The Wnt-NLK signaling pathway inhibits A-Myb activity by inhibiting the association with coactivator CBP and methylating histone H3.

CREBBP MYB MYBL1

2.60e-08639316055500
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

SAFB2 SRRT UPF3B ABCF1 PBRM1 THOC2 TCERG1 DHX29 BAZ1A RCC2 GNL3 HDAC1

2.99e-081425391230948266
Pubmed

Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.

UPF3B ABCF1 PBRM1 THOC2 RCC2 GNL3 RBMX2 HSP90AA1

5.78e-0848639830940648
Pubmed

UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination.

SAFB2 ABCF1 SPAG17 THOC2 SAP18 RCC2 GNL3 ZMAT2

6.25e-0849139836273042
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

SAFB2 SRRT THOC2 TCERG1 CWC25 BAZ1A RCC2 GNL3 ZMAT2 HSP90AA1

7.11e-08954391036373674
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

SAFB2 SRRT UPF3B ABCF1 THOC2 DHX29 SAP18 RCC2 GNL3

7.44e-0871339929802200
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

SRRT CHD9 UPF3B ABCF1 TBC1D4 THOC2 SAP18 RCC2 GNL3 HSP90AA1 HDAC1

8.02e-081247391127684187
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

SAFB2 SRRT ABCF1 PBRM1 TCERG1 BAZ1A HSP90AA1

8.02e-0833239732786267
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

SRRT UPF3B ABCF1 ZNHIT6 DHX29 RCC2 GNL3 RBMX2 HSP90AA1 HDAC1

8.38e-08971391033306668
Pubmed

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.

SAFB2 TCERG1 BAZ1A SAP18 HDAC1

1.15e-0710439526167872
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SAFB2 SRRT PBRM1 THOC2 TCERG1 BAZ1A SAP18 RCC2 GNL3 RBMX2 HDAC1

1.16e-071294391130804502
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

POLR3D ABCF1 ZNHIT6 TBC1D4 HSP90AA5P SAP18 RCC2 GNL3 HSP90AA1 HDAC1 HSP90AB3P

1.59e-071335391129229926
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SAFB2 SRRT CHD9 ABCF1 THOC2 TCERG1 SAP18 RCC2 RBMX2 HSP90AA1

2.28e-071082391038697112
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

SAFB2 SRRT PBRM1 THOC2 SAP18 GNL3

3.01e-0724439629884807
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

SRRT ABCF1 PBRM1 BAZ1A SAP18 GNL3 HSP90AA1 HDAC1

3.06e-0760539828977666
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

UPF3B PBRM1 THOC2 TCERG1 HSP90AA5P DHX29 HSP90AA1 HDAC1 HSP90AB3P

3.18e-0784739935235311
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SRRT ABCF1 PBRM1 TCERG1 DHX29 BAZ1A CWC27 RCC2 GNL3 RBMX2 HDAC1

4.99e-071497391131527615
Pubmed

Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.

SAFB2 ABCF1 TCERG1 SAP18 RCC2 HSP90AA1 HDAC1

5.45e-0744139731239290
Pubmed

The HSP90 family of genes in the human genome: insights into their divergence and evolution.

HSP90AA5P HSP90AA1 HSP90AB3P

7.23e-071639316269234
Pubmed

Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns.

PBRM1 CREBBP HDAC1

8.77e-071739314519686
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

SAFB2 SRRT ABCF1 THOC2 TCERG1 SAP18 RCC2 GNL3 HSP90AA1 HDAC1

8.96e-071257391036526897
Pubmed

The EGFR-ZNF263 signaling axis silences SIX3 in glioblastoma epigenetically.

SAFB2 SRRT BAZ1A SAP18

9.25e-076639432051553
Pubmed

Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion.

UPF3B POLR3D CWC25 CWC27 TCP11L1 GNL3 HSP90AA1 HDAC1

9.58e-0770439832994395
Pubmed

The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome.

CWC25 CWC27

1.23e-06239219941820
Pubmed

Pediatric-type diffuse low-grade glioma with MYB/MYBL1 alteration: report of 2 cases.

MYB MYBL1

1.23e-06239236074655
Pubmed

MYB and MYBL1 in adenoid cystic carcinoma: diversity in the mode of genomic rearrangement and transcripts.

MYB MYBL1

1.23e-06239229410490
Pubmed

Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system.

CREBBP MYB

1.23e-06239223980173
Pubmed

DNA binding and transactivation activity of A-myb, a c-myb-related gene.

MYB MYBL1

1.23e-0623927987850
Pubmed

Increased affinity of c-Myb for CREB-binding protein (CBP) after CBP-induced acetylation.

CREBBP MYB

1.23e-06239211073948
Pubmed

Adenoid cystic carcinoma of the Bartholin's gland is underpinned by MYB- and MYBL1- rearrangements.

MYB MYBL1

1.23e-06239238368814
Pubmed

Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course.

MYB MYBL1

1.23e-06239231563982
Pubmed

Regulatory domains of the A-Myb transcription factor and its interaction with the CBP/p300 adaptor molecules.

CREBBP MYBL1

1.23e-0623929210395
Pubmed

Expression of mouse c-myb during embryonic development.

MYB MYBL1

1.23e-0623928570177
Pubmed

Arrest of spermatogenesis and defective breast development in mice lacking A-myb.

MYB MYBL1

1.23e-0623929109487
Pubmed

Solution structure of the KIX domain of CBP bound to the transactivation domain of c-Myb.

CREBBP MYB

1.23e-06239215019774
Pubmed

A single-center study of the clinicopathologic correlates of gliomas with a MYB or MYBL1 alteration.

MYB MYBL1

1.23e-06239231595312
Pubmed

Detecting MYB and MYBL1 fusion genes in tracheobronchial adenoid cystic carcinoma by targeted RNA-sequencing.

MYB MYBL1

1.23e-06239231028361
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

SAFB2 ABCF1 PBRM1 THOC2 TCERG1 SAP18 GNL3 RBMX2 HSP90AA1 HDAC1

1.38e-061318391030463901
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

PBRM1 BAZ1A CREBBP HDAC1

1.55e-067539425593309
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SAFB2 SRRT ABCF1 TBC1D4 TCERG1 DHX29 BAZ1A CREBBP GNL3 HSP90AA1

1.74e-061353391029467282
Pubmed

ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.

SAFB2 PBRM1 SAP18 GNL3 RBMX2 HDAC1

1.75e-0633039633301849
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

SRRT UPF3B PBRM1 THOC2 TCERG1 CWC25 BAZ1A SAP18 GNL3 RBMX2

1.96e-061371391036244648
Pubmed

A comprehensive resource of interacting protein regions for refining human transcription factor networks.

TCERG1 CWC25 ZMAT2 HSP90AA1 MYB

2.35e-0619139520195357
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

SAFB2 ABCF1 BAZ1A RCC2 GNL3 HDAC1

2.41e-0634939625665578
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

SRRT CHD9 ABCF1 THOC2 RCC2 GNL3 HSP90AA1 HDAC1

2.69e-0680939832129710
Pubmed

PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis.

SAFB2 PBRM1 GNL3 HSP90AA1

3.22e-069039430699358
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

SRRT THOC2 TCERG1 BAZ1A RCC2 HSP90AA1 HDAC1

3.47e-0658339729844126
Pubmed

Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.

CREBBP MYB

3.67e-06339224340053
Pubmed

A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.

CREBBP MYB

3.67e-06339212384703
Pubmed

Roles of phosphorylation and helix propensity in the binding of the KIX domain of CREB-binding protein by constitutive (c-Myb) and inducible (CREB) activators.

CREBBP MYB

3.67e-06339212196545
Pubmed

Inhibition of cyclin A/Cdk2 phosphorylation impairs B-Myb transactivation function without affecting interactions with DNA or the CBP coactivator.

CREBBP MYB

3.67e-06339211423988
Pubmed

The myb gene family in cell growth, differentiation and apoptosis.

MYB MYBL1

3.67e-06339210378697
Pubmed

TAp73 protein stability is controlled by histone deacetylase 1 via regulation of Hsp90 chaperone function.

HSP90AA1 HDAC1

3.67e-06339223362263
Pubmed

MYBL1 rearrangements and MYB amplification in breast adenoid cystic carcinomas lacking the MYB-NFIB fusion gene.

MYB MYBL1

3.67e-06339229149504
Pubmed

NudCL2 is required for cytokinesis by stabilizing RCC2 with Hsp90 at the midbody.

RCC2 HSP90AA1

3.67e-06339238801297
Pubmed

Structural basis for cooperative transcription factor binding to the CBP coactivator.

CREBBP MYB

3.67e-06339216253272
Pubmed

Nucleolin, a novel partner for the Myb transcription factor family that regulates their activity.

MYB MYBL1

3.67e-06339210660576
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

SAFB2 PBRM1 THOC2 TCERG1 BAZ1A SAP18 HSP90AA1 HDAC1

3.77e-0684739835850772
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

ABCF1 PBRM1 TCERG1 DHX29 HSP90AB3P

4.18e-0621539535973513
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

CHD9 PBRM1 BAZ1A CWC27 GNL3 RBMX2 HDAC1

4.56e-0660839736089195
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

SRRT PBRM1 GNL3 HSP90AA1 HDAC1

4.68e-0622039535785414
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

SRRT ABCF1 PBRM1 TCERG1 DHX29 SAP18

4.98e-0639639626687479
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

SRRT PBRM1 SAP18 HDAC1

5.51e-0610339432744500
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

TBC1D4 THOC2 TCERG1 RCC2 GNL3 HSP90AA1 HDAC1

6.25e-0663839733239621
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

SAFB2 SRRT THOC2 SAP18 GNL3 HSP90AA1 HDAC1

7.20e-0665239731180492
Pubmed

HNF1beta/TCF2 mutations impair transactivation potential through altered co-regulator recruitment.

CREBBP HDAC1

7.34e-06439215509593
Pubmed

Temporal patterns of A-myb and B-myb gene expression during testis development.

MYB MYBL1

7.34e-0643928808690
Pubmed

Recruitment of a SAP18-HDAC1 complex into HIV-1 virions and its requirement for viral replication.

SAP18 HDAC1

7.34e-06439219503603
Pubmed

Histone deacetylase inhibitors induce FPGS mRNA expression and intracellular accumulation of long-chain methotrexate polyglutamates in childhood acute lymphoblastic leukemia: implications for combination therapy.

CREBBP HDAC1

7.34e-06439220072153
Pubmed

MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation.

CREBBP HDAC1

7.34e-06439212426395
Pubmed

Trans-repressive effect of NUP98-PMX1 on PMX1-regulated c-FOS gene through recruitment of histone deacetylase 1 by FG repeats.

CREBBP HDAC1

7.34e-06439216651408
Pubmed

Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter.

CREBBP HDAC1

7.34e-06439211115394
Pubmed

BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation.

CREBBP HDAC1

1.22e-05539211003650
Pubmed

Antithetic effects of MBD2a on gene regulation.

CREBBP HDAC1

1.22e-05539212665568
Pubmed

GATA3 acetylation at K119 by CBP inhibits cell migration and invasion in lung adenocarcinoma.

CREBBP HDAC1

1.22e-05539229453984
Pubmed

Regulation of murine TGFbeta2 by Pax3 during early embryonic development.

CREBBP HDAC1

1.22e-05539216787918
Pubmed

Suppression of the SAP18/HDAC1 complex by targeting TRIM56 and Nanog is essential for oncogenic viral FLICE-inhibitory protein-induced acetylation of p65/RelA, NF-κB activation, and promotion of cell invasion and angiogenesis.

SAP18 HDAC1

1.22e-05539230670829
Pubmed

Site-specific acetylation of the fetal globin activator NF-E4 prevents its ubiquitination and regulates its interaction with the histone deacetylase, HDAC1.

CREBBP HDAC1

1.22e-05539215273251
Pubmed

Differential sensitivity of v-Myb and c-Myb to Wnt-1-induced protein degradation.

CREBBP MYB

1.22e-05539215308626
Pubmed

A splice variant of stress response gene ATF3 counteracts NF-kappaB-dependent anti-apoptosis through inhibiting recruitment of CREB-binding protein/p300 coactivator.

CREBBP HDAC1

1.22e-05539216291753
Pubmed

The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1.

CREBBP HDAC1

1.22e-05539211931769
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

PARD3B UPF3B PBRM1 BAZ1A SAP18 ZMAT2

1.30e-0546939627634302
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

SAFB2 SRRT ABCF1 PBRM1 THOC2 BAZ1A RCC2 GNL3

1.50e-05102439824711643
Pubmed

Acetylation of Stat1 modulates NF-kappaB activity.

CREBBP HDAC1

1.83e-05639216481475
Pubmed

Nuclear tumor necrosis factor receptor-associated factor 6 in lymphoid cells negatively regulates c-Myb-mediated transactivation through small ubiquitin-related modifier-1 modification.

HDAC1 MYB

1.83e-05639218093978
Pubmed

Postsynaptic CaV1.1-driven calcium signaling coordinates presynaptic differentiation at the developing neuromuscular junction.

NEFH RYR1

1.83e-05639231804576
Pubmed

Interaction of EVI1 with cAMP-responsive element-binding protein-binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles.

CREBBP HDAC1

1.83e-05639211568182
Pubmed

UHRF1 inhibits MDR1 gene transcription and sensitizes breast cancer cells to anticancer drugs.

CREBBP HDAC1

1.83e-05639220037778
Pubmed

Oncogenic activation of c-Myb correlates with a loss of negative regulation by TIF1beta and Ski.

CREBBP MYB

1.83e-05639214761981
Pubmed

Histone deacetylase 3 binds to and regulates the GCMa transcription factor.

CREBBP HDAC1

1.83e-05639216528103
Pubmed

Bach1 Represses Wnt/β-Catenin Signaling and Angiogenesis.

CREBBP HDAC1

1.83e-05639226123998
InteractionMYCN interactions

SAFB2 SRRT UPF3B POLR3D ABCF1 THOC2 CWC25 SAP18 RCC2 GNL3 RBMX2 ZMAT2 HSP90AA1 HDAC1

1.30e-0713733914int:MYCN
InteractionHECTD1 interactions

SAFB2 SRRT UPF3B ABCF1 PBRM1 THOC2 TCERG1 DHX29 BAZ1A RCC2 GNL3 HDAC1

1.98e-079843912int:HECTD1
InteractionTNIP1 interactions

SAFB2 UPF3B ABCF1 ZNHIT6 THOC2 TCERG1 HSP90AA5P RCC2 GNL3 RBMX2 ZMAT2 HSP90AA1 HDAC1

2.47e-0712173913int:TNIP1
InteractionCEBPA interactions

SAFB2 CHD9 UPF3B ABCF1 THOC2 TCERG1 BAZ1A CREBBP SAP18 RCC2 ZMAT2 HDAC1 MYB

3.21e-0712453913int:CEBPA
InteractionNUPR1 interactions

SAFB2 SRRT ABCF1 THOC2 TCERG1 BAZ1A CWC27 SAP18 RCC2 HDAC1

4.89e-076833910int:NUPR1
InteractionZMYND11 interactions

PBRM1 SAP18 HSP90AA1 HDAC1 MYB

1.01e-0694395int:ZMYND11
InteractionCHD3 interactions

SRRT PBRM1 TCERG1 BAZ1A CREBBP SAP18 GNL3 HSP90AA1 HDAC1 MYB

1.25e-067573910int:CHD3
InteractionSUMO2 interactions

SAFB2 SRRT ABCF1 PBRM1 TCERG1 BAZ1A HSP90AA1 HDAC1 MYB

1.46e-06591399int:SUMO2
InteractionNAA40 interactions

SAFB2 UPF3B ABCF1 THOC2 TCERG1 DHX29 BAZ1A RCC2 GNL3 ZMAT2 HSP90AA1

1.59e-069783911int:NAA40
InteractionCEBPB interactions

SAFB2 SRRT ABCF1 PBRM1 TCERG1 BAZ1A CREBBP SAP18 RCC2 GNL3 HSP90AA1 HDAC1 MYB

1.72e-0614433913int:CEBPB
InteractionH3-4 interactions

ABCF1 PBRM1 TBC1D4 CREBBP RCC2 HSP90AA1 HDAC1 MYB

1.88e-06448398int:H3-4
InteractionCDKL4 interactions

HSP90AA5P HSP90AA1 HSP90AB3P

1.89e-0613393int:CDKL4
InteractionPRP4K interactions

SRRT PARD3B THOC2 TCERG1 BAZ1A SAP18 HSP90AA1

2.85e-06329397int:PRP4K
InteractionDDX23 interactions

SAFB2 THOC2 TCERG1 CWC25 CWC27 SAP18 GNL3 RBMX2

3.14e-06480398int:DDX23
InteractionMECP2 interactions

SAFB2 SRRT CHD9 ABCF1 THOC2 TCERG1 BAZ1A SAP18 RCC2 RBMX2 HSP90AA1 HDAC1

3.40e-0612873912int:MECP2
InteractionPOLR1G interactions

CHD9 POLR3D PBRM1 CWC27 GNL3 RBMX2 ZMAT2 HDAC1

3.60e-06489398int:POLR1G
InteractionZC3H18 interactions

SAFB2 SRRT THOC2 TCERG1 SAP18 RCC2 GNL3 RBMX2 ZMAT2 HSP90AA1

4.66e-068773910int:ZC3H18
InteractionIFI16 interactions

SAFB2 UPF3B ABCF1 PBRM1 DHX29 SAP18 RCC2 GNL3 HSP90AA1

6.82e-06714399int:IFI16
InteractionUNC45B interactions

HSP90AA5P HSP90AA1 HSP90AB3P

1.01e-0522393int:UNC45B
InteractionGUCY2D interactions

HSP90AA5P HSP90AA1 HSP90AB3P

1.16e-0523393int:GUCY2D
InteractionSNRNP70 interactions

SAFB2 SRRT UPF3B ABCF1 THOC2 DHX29 SAP18 RCC2 GNL3 HDAC1

1.28e-059843910int:SNRNP70
InteractionSMC5 interactions

SAFB2 SRRT THOC2 TCERG1 CWC25 BAZ1A RCC2 GNL3 ZMAT2 HSP90AA1

1.47e-0510003910int:SMC5
InteractionCCDC117 interactions

HSP90AA5P HSP90AA1 HSP90AB3P

1.69e-0526393int:CCDC117
InteractionDOT1L interactions

SAFB2 PBRM1 THOC2 TCERG1 BAZ1A SAP18 GNL3 HSP90AA1 HDAC1

1.82e-05807399int:DOT1L
InteractionMEN1 interactions

SAFB2 SRRT PBRM1 THOC2 TCERG1 BAZ1A SAP18 HSP90AA1 HDAC1 MYB

1.89e-0510293910int:MEN1
InteractionSNRPC interactions

SAFB2 SRRT PARD3B THOC2 TCERG1 SAP18 ZMAT2

1.90e-05440397int:SNRPC
InteractionZBTB2 interactions

SAFB2 PBRM1 CREBBP SAP18 GNL3 RBMX2 HDAC1

2.19e-05450397int:ZBTB2
InteractionBRD7 interactions

UPF3B ABCF1 PBRM1 THOC2 RCC2 GNL3 RBMX2 HSP90AA1

2.47e-05637398int:BRD7
InteractionPPARG interactions

SAFB2 PBRM1 CREBBP GNL3 HSP90AA1 HDAC1

2.54e-05307396int:PPARG
InteractionSTK35 interactions

HSP90AA5P HSP90AA1 HSP90AB3P

2.62e-0530393int:STK35
InteractionMYLK4 interactions

HSP90AA5P RCC2 HSP90AA1 HSP90AB3P

2.71e-0590394int:MYLK4
InteractionGRK4 interactions

SRRT TCERG1 HSP90AA1

2.90e-0531393int:GRK4
InteractionBMI1 interactions

SAFB2 SRRT DHX29 BAZ1A CREBBP SAP18 RCC2 MYB

3.14e-05659398int:BMI1
InteractionATF3 interactions

POLR3D CREBBP HSP90AA1 HDAC1

3.22e-0594394int:ATF3
InteractionKCNA3 interactions

CHD9 TBC1D4 THOC2 TCERG1 DHX29 RCC2 RYR1 HSP90AA1 HDAC1

3.32e-05871399int:KCNA3
InteractionCFAP70 interactions

CFAP70 HSP90AA1

3.64e-055392int:CFAP70
InteractionCIC interactions

SRRT THOC2 TCERG1 BAZ1A RCC2 HSP90AA1 HDAC1 MYB

3.65e-05673398int:CIC
InteractionBRD3 interactions

CHD9 ABCF1 PBRM1 THOC2 TCERG1 BAZ1A SAP18

3.97e-05494397int:BRD3
InteractionCHMP4C interactions

SAFB2 ABCF1 HSP90AA5P SAP18 GNL3 HSP90AA1 HDAC1 HSP90AB3P

4.22e-05687398int:CHMP4C
InteractionOBSL1 interactions

SAFB2 SRRT ABCF1 PBRM1 CFAP70 THOC2 DHX29 RCC2 GNL3

4.37e-05902399int:OBSL1
InteractionTOP1 interactions

SAFB2 SRRT PBRM1 TCERG1 DHX29 BAZ1A SAP18 ZMAT2

4.63e-05696398int:TOP1
InteractionSMARCA2 interactions

PBRM1 BAZ1A CREBBP SAP18 HDAC1 MYB

4.96e-05346396int:SMARCA2
InteractionRECQL4 interactions

POLR3D ABCF1 ZNHIT6 TBC1D4 HSP90AA5P SAP18 RCC2 GNL3 HSP90AA1 HDAC1 HSP90AB3P

5.16e-0514123911int:RECQL4
InteractionSNRPB interactions

SAFB2 SRRT PARD3B TCERG1 CWC27 SAP18 ZMAT2

5.30e-05517397int:SNRPB
InteractionFZR1 interactions

SRRT UPF3B ABCF1 ZNHIT6 DHX29 RCC2 GNL3 RBMX2 HSP90AA1 HDAC1

5.75e-0511723910int:FZR1
InteractionSRMS interactions

HSP90AA5P HSP90AA1 HSP90AB3P

6.30e-0540393int:SRMS
InteractionCLK3 interactions

SAFB2 SRRT SAP18 HSP90AA1 HSP90AB3P

6.30e-05220395int:CLK3
InteractionOGT interactions

UPF3B POLR3D CWC25 CWC27 CREBBP TCP11L1 GNL3 HSP90AA1 HDAC1

6.53e-05950399int:OGT
InteractionEFTUD2 interactions

SRRT UPF3B ABCF1 TBC1D4 TCERG1 CWC27 SAP18 RCC2 GNL3 HSP90AA1 HDAC1

6.54e-0514493911int:EFTUD2
InteractionCIT interactions

SAFB2 UPF3B ABCF1 SPAG17 THOC2 TCERG1 SAP18 GNL3 HSP90AA1 HDAC1 HSP90AB3P

6.58e-0514503911int:CIT
InteractionAURKC interactions

HSP90AA5P HSP90AA1 HSP90AB3P

7.84e-0543393int:AURKC
InteractionSGK2 interactions

HSP90AA5P HSP90AA1 HSP90AB3P

7.84e-0543393int:SGK2
InteractionCAMKV interactions

CHD9 CWC27 SAP18 HSP90AA1

7.84e-05118394int:CAMKV
InteractionPRC1 interactions

SAFB2 ITGA10 SRRT ABCF1 PBRM1 TCERG1 DHX29 SAP18 GNL3

7.85e-05973399int:PRC1
InteractionCENPA interactions

SRRT PBRM1 THOC2 BAZ1A ZMAT2 HDAC1

7.97e-05377396int:CENPA
InteractionFUS interactions

SAFB2 SRRT PBRM1 THOC2 TCERG1 CREBBP GNL3 HSP90AA1

8.35e-05757398int:FUS
InteractionCAMK2G interactions

TBC1D4 THOC2 RYR1 HSP90AA1 HDAC1

9.51e-05240395int:CAMK2G
InteractionRBBP4 interactions

BAZ1A CREBBP SAP18 GNL3 HSP90AA1 HDAC1 MYBL1

1.01e-04573397int:RBBP4
InteractionSTIP1 interactions

TBC1D4 THOC2 TCERG1 HSP90AA5P RCC2 GNL3 HSP90AA1 HDAC1 HSP90AB3P

1.01e-041006399int:STIP1
InteractionTSSK6 interactions

HSP90AA5P HSP90AA1 HSP90AB3P

1.02e-0447393int:TSSK6
InteractionH2BC8 interactions

UPF3B PBRM1 TCERG1 BAZ1A CWC27 RCC2 ZMAT2

1.04e-04576397int:H2BC8
InteractionUBE2O interactions

SAFB2 ABCF1 SPAG17 THOC2 SAP18 RCC2 GNL3 ZMAT2

1.12e-04790398int:UBE2O
InteractionH2BC3 interactions

CHD9 PBRM1 BAZ1A CREBBP HDAC1 MYB

1.20e-04406396int:H2BC3
InteractionKIF23 interactions

SAFB2 SRRT CHD9 ABCF1 THOC2 HSP90AA5P SAP18 GNL3 HSP90AB3P

1.22e-041031399int:KIF23
InteractionHMGA1 interactions

SAFB2 PBRM1 BAZ1A CWC27 CREBBP HSP90AA1

1.42e-04419396int:HMGA1
InteractionBAP1 interactions

ABCF1 TBC1D4 TCERG1 CREBBP RCC2 TCP11L1 GNL3 HSP90AA1 HDAC1 MYB

1.49e-0413143910int:BAP1
InteractionELF3 interactions

PBRM1 CREBBP GNL3

1.55e-0454393int:ELF3
InteractionGBP2 interactions

HSP90AA5P HSP90AA1 HSP90AB3P

1.55e-0454393int:GBP2
InteractionBIRC3 interactions

SRRT ABCF1 PBRM1 THOC2 TCERG1 DHX29 BAZ1A RCC2 GNL3 HDAC1

1.69e-0413343910int:BIRC3
InteractionNUP43 interactions

SRRT CHD9 PBRM1 BAZ1A RCC2 GNL3 RBMX2

1.73e-04625397int:NUP43
InteractionAMHR2 interactions

HSP90AA5P HSP90AA1 HSP90AB3P

1.73e-0456393int:AMHR2
InteractionZNF263 interactions

SAFB2 SRRT BAZ1A SAP18

1.93e-04149394int:ZNF263
InteractionWDR5 interactions

SRRT ABCF1 CREBBP SAP18 RCC2 GNL3 HSP90AA1 HDAC1 MYB

2.01e-041101399int:WDR5
InteractionCAMK4 interactions

CREBBP HSP90AA1 HSP90AB3P

2.02e-0459393int:CAMK4
InteractionSUZ12 interactions

SAFB2 PARD3B UPF3B PBRM1 THOC2 SAP18 HDAC1

2.08e-04644397int:SUZ12
InteractionRBBP5 interactions

SRRT CREBBP SAP18 HDAC1 MYB

2.19e-04287395int:RBBP5
InteractionRPS6 interactions

SAFB2 UPF3B CWC25 DHX29 GNL3 RBMX2 ZMAT2 HSP90AA1

2.25e-04874398int:RPS6
InteractionITK interactions

HSP90AA5P HSP90AA1 HSP90AB3P

2.34e-0462393int:ITK
InteractionDHX8 interactions

TCERG1 CWC25 CWC27 SAP18 RBMX2

2.37e-04292395int:DHX8
InteractionMYBL1 interactions

CREBBP MYBL1

2.38e-0412392int:MYBL1
InteractionNR2C2 interactions

SAFB2 ABCF1 PBRM1 THOC2 TCERG1 SAP18 GNL3 RBMX2 HSP90AA1 HDAC1

2.55e-0414033910int:NR2C2
InteractionHES1 interactions

CREBBP HSP90AA1 HDAC1

2.57e-0464393int:HES1
InteractionSF3A1 interactions

SRRT TCERG1 CWC27 SAP18 ZMAT2 HDAC1

2.68e-04471396int:SF3A1
InteractionH3C1 interactions

PBRM1 BAZ1A CREBBP RCC2 GNL3 ZMAT2 HDAC1 MYB

2.77e-04901398int:H3C1
InteractionHLF interactions

CREBBP MYB

2.81e-0413392int:HLF
InteractionRLF interactions

SRRT HDAC1 MYB

2.82e-0466393int:RLF
InteractionTTC4 interactions

GNL3 HSP90AA1 HDAC1 HSP90AB3P

2.85e-04165394int:TTC4
InteractionSSRP1 interactions

SAFB2 SRRT PBRM1 TCERG1 SAP18 GNL3 ZMAT2

3.03e-04685397int:SSRP1
InteractionSNRPA interactions

SAFB2 SRRT TCERG1 SAP18 GNL3 ZMAT2

3.03e-04482396int:SNRPA
InteractionHMGB1 interactions

SAFB2 SRRT CREBBP GNL3 HSP90AA1 HDAC1

3.17e-04486396int:HMGB1
InteractionEED interactions

SAFB2 SRRT ABCF1 PBRM1 THOC2 TCERG1 BAZ1A GNL3 HSP90AA1 HDAC1

3.23e-0414453910int:EED
InteractionNLK interactions

CREBBP MYB MYBL1

3.35e-0470393int:NLK
InteractionSMYD3 interactions

HSP90AA5P HSP90AA1 HSP90AB3P

3.50e-0471393int:SMYD3
InteractionEIF4A3 interactions

SRRT UPF3B THOC2 CWC27 SAP18 GNL3

3.64e-04499396int:EIF4A3
InteractionNPM1 interactions

SRRT PBRM1 THOC2 TCERG1 DHX29 GNL3 RBMX2 HSP90AA1 HDAC1

3.83e-041201399int:NPM1
InteractionH2AC4 interactions

CHD9 PBRM1 BAZ1A CREBBP HDAC1 MYB

3.92e-04506396int:H2AC4
InteractionCDK11A interactions

SRRT HSP90AA5P HSP90AA1 HSP90AB3P

3.97e-04180394int:CDK11A
InteractionRBBP7 interactions

BAZ1A CREBBP SAP18 GNL3 HSP90AA1 HDAC1

3.97e-04507396int:RBBP7
InteractionCSNK2A1 interactions

SRRT UPF3B BAZ1A CREBBP RCC2 HSP90AA1 HDAC1 MYB

4.12e-04956398int:CSNK2A1
InteractionGRK5 interactions

ABCF1 BAZ1A SAP18 HSP90AA1

4.13e-04182394int:GRK5
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

SAP18 HDAC1

6.57e-0592521306
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MYB MYBL1

2.42e-0353252532
GeneFamilyX-linked mental retardation|Angiotensin receptors

UPF3B THOC2

2.42e-0353252103
GeneFamilyRNA binding motif containing

SAFB2 RBMX2

3.47e-02213252725
CoexpressionGSE40274_GATA1_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

UPF3B ZNHIT6 TBC1D4 RCC2 MYB

1.01e-05200385M9165
CoexpressionLEE_BMP2_TARGETS_DN

TCERG1 DHX29 BAZ1A RCC2 GNL3 RBMX2 HSP90AA1 HDAC1

3.78e-05904388M2325
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

NAP1L3 PBRM1 DHX29 BAZ1A CWC27 HSP90AA1 MYBL1

3.83e-05656387M18979
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

CHD9 UPF3B ABCF1 TRAF3IP1 THOC2 TCERG1 BAZ1A GNL3 RBMX2 HSP90AA1 MYB MYBL1

5.35e-0614593812facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

CHD9 UPF3B ABCF1 TRAF3IP1 THOC2 TCERG1 BAZ1A GNL3 RBMX2 HSP90AA1 MYBL1

8.17e-0612573811facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

UPF3B ABCF1 TRAF3IP1 TCERG1 BAZ1A MYBL1

1.75e-05311386Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

UPF3B ABCF1 TRAF3IP1 TCERG1 BAZ1A GNL3 HSP90AA1 MYBL1 HSP90AB3P

4.78e-05989389Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasDevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#4_top-relative-expression-ranked_1000

PARD3B TBC1D4 BAZ1A C4orf54 MYB

1.67e-04293385gudmap_developingKidney_e15.5_Podocyte cells_1000_k4
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000

NAP1L3 CHD9 PBRM1 THOC2 CREBBP

2.63e-04323385gudmap_developingGonad_e11.5_ovary + mesonephros_k2_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500_K1

CHD9 UPF3B POLR3D ABCF1 THOC2 BAZ1A GNL3 HSP90AA1 MYB

2.70e-041241389facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5

TRAF3IP1 THOC2 BAZ1A CREBBP

3.33e-04186384Facebase_RNAseq_e10.5_Mandibular Arch_500_K5
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

CFAP70 SPAG17 TRAF3IP1 HSP90AA1 MYB

6.20e-071883958f30535a32968a81a304315a49c0d90a77d36948
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1 HSP90AA1 MYB

6.70e-07191395acd844b477a069b2dcf07b2998e1b5c87dc0eb94
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

SAFB2 NEFH UPF3B THOC2 HSP90AA1

7.80e-071973950fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell368C-Lymphocytic-NK_cells-NK_cell_A|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SRRT CWC25 MYBL1

6.27e-06413939f609afcf34f0b486dfe51e5f0e903fe357d3e91
ToppCellP03-Epithelial-airway_epithelial_cell-club_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP70 SPAG17 TRAF3IP1 MYB

1.87e-0518139460a91587c59029a34e7bec1255083337fe21b72a
ToppCellP03-Epithelial-airway_epithelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP70 SPAG17 TRAF3IP1 MYB

1.87e-051813941ea21d860d4d7abab3e21e130a16d044006656ee
ToppCelldroplet-Marrow-nan-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RCC2 TCP11L1 GNL3 MYB

1.95e-0518339424db9cc717e651586317c6a8e03a3401651273c1
ToppCelldroplet-Marrow-nan-3m-Myeloid-Cd4_positive_Macrophages|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RCC2 TCP11L1 GNL3 MYB

1.95e-0518339492ef926e6c1de8477fa4f35d1dae85482d8009de
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

PARD3B PBRM1 TRAF3IP1 CREBBP

2.08e-0518639403db813598b67b1e08f759758a1c2023396921fa
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1 MYB

2.21e-05189394b55de812043b670cbde810d7d42f45909b6d66ef
ToppCellPND01-Epithelial-Epithelial_Airway|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1 MYB

2.21e-0518939438cde34295566a4ecaf7d0a81c5a192cf17d0459
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1 MYB

2.21e-05189394a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1 MYB

2.21e-051893944e83e49d1265ffe507fdb72924c77c4d1c73f0bd
ToppCellEpithelial-D_(Ciliated)|World / shred on cell class and cell subclass (v4)

CFAP70 SPAG17 TRAF3IP1 MYB

2.21e-051893940bf560b595c7a8450a46bc821b742b67965bd9f9
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 HSP90AA1 MYB

2.30e-051913941e21de183a9c09cfb6aad3f9b948087fb6bad061
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1 MYB

2.30e-05191394bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1 MYB

2.30e-051913946880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 HSP90AA1 MYB

2.30e-051913948688708c9183ebcb200596501dc30cc12073f151
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 HSP90AA1 MYB

2.30e-05191394e8d56e9f43943e9cc4dce83f2c234f19c2dd487d
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1 MYB

2.30e-0519139496483adb97c81208aa513782550acd8a08b63866
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 HSP90AA1 MYB

2.30e-0519139452e8d7dfaf1ebb6df8bf3a1f4546af59faa67657
ToppCellE16.5-Epithelial-Epithelial_Airway|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 HSP90AA1 MYB

2.35e-05192394bb7eb51bc079acacde42d8e55ba06d03eba2ea28
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1 MYB

2.35e-05192394b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 HSP90AA1 MYB

2.35e-05192394a50a6279371b3be682e334082637b7ab76b9a6e5
ToppCellPND03-Epithelial-Epithelial_Airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1 MYB

2.35e-051923942d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCellCV-Moderate-6|Moderate / Virus stimulation, Condition and Cluster

ABCF1 PBRM1 BAZ1A MYBL1

2.50e-051953942b8a72d7e755b9655c7a496000d10ff06e50862b
ToppCellEntopeduncular-Neuronal-Excitatory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

C4orf54 SCN4A MYB

5.27e-058339348db75711526364d2a8165524d3cbb92129ddba3
ToppCellControl-Lymphoid_T/NK-dn_T|Control / Disease group, lineage and cell class

TBC1D4 CFAP70 MYB

1.86e-0412739358f47cb079c596a9119d8bf158c1681b28360ac3
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-dn_T-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TBC1D4 CFAP70 MYB

1.86e-04127393d4c6e65a4e4c2c9422bea11b9f78e4beabf04961
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-dn_T|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TBC1D4 CFAP70 MYB

1.86e-041273934ccda89414f18313269be2f5a1542314b1b10572
ToppCellCiliated_cells-B-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

NAP1L3 CFAP70 SPAG17

2.98e-041493936399c5a2f06d79f020dece252526f1c0c110d569
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP70 SPAG17 MYB

3.47e-04157393410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEFH POLR3D MYBL1

3.95e-0416439330c3c25b05a403a509b2e755c2f0878fecb10a02
ToppCellCiliated_cells-A-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

CFAP70 SPAG17 MYB

4.38e-041703933d3a03979014df3a05c49be18010c6b94d786707
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RYR1 MYB MYBL1

4.38e-04170393be2a34c70665d8d11332b1a70eda03d77cb7f7dd
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP70 SPAG17 CNGB1

4.46e-041713931854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 MYB

4.46e-041713934f2a83d8091f1fd29542d2e5add57fd482e921b5
ToppCelldroplet-Lung-nan-21m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D4 TCP11L1 RYR1

4.61e-041733932eb6e9fc3a3654f6f86fbd112e80a18814afd103
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRAF3IP1 SAP18 RYR1

4.61e-04173393b6bb2a136a40f0946bbcde8d5972d3f059d080c7
ToppCellfacs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TBC1D4 BAZ1A RYR1

4.69e-041743936688424fc4e40c3c4a89669a2bc79369a726f1e6
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TBC1D4 TCP11L1 RYR1

4.77e-0417539373f25bd54309aed1480ddc44bdab518b17e71f92
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP70 SPAG17 MYB

5.01e-04178393de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D4 BAZ1A RYR1

5.01e-041783938c5e9fab7b55a654ccaabf2c4d02397399d94616
ToppCellfacs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TBC1D4 BAZ1A RYR1

5.09e-0417939355fde77dae7f9e7f3431c3185d14212a25af83df
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 MYB

5.18e-041803935c9d2d44d840cd4ec7d42d43446ba2b689e7ec43
ToppCellCiliated_cells-A-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

CFAP70 SPAG17 TRAF3IP1

5.18e-04180393d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NAP1L3 TBC1D4 MYBL1

5.18e-04180393d9dae9db8e17f6990032ee6cfa8393fae4768ca5
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

CFAP70 RCC2 MYBL1

5.18e-0418039312f3c4c4aa7fe03c0ef847bd4d4942c808015f5f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

CFAP70 RCC2 MYBL1

5.18e-041803932a28fbfe10a340c8662c2c8be33792f41fc09088
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP70 SPAG17 TRAF3IP1

5.18e-041803931f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 MYB

5.18e-04180393c60e74fbbd815a0251253a19dc520a254b2e1762
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

CFAP70 RCC2 MYBL1

5.18e-041803931bc01bb76d0d3f8db74f9244436d3e6d6015ed5d
ToppCellFLU-Healthy-0|FLU / Virus stimulation, Condition and Cluster

NAP1L3 CFAP70 MYBL1

5.43e-04183393058604ddb06b3bef131183d86b83b422dae8f6cb
ToppCellFLU-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

NAP1L3 CFAP70 MYBL1

5.43e-041833937a6f18246c39864479e114f698581f667fa9c600
ToppCellP07-Epithelial-airway_epithelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP70 SPAG17 MYB

5.52e-04184393a5e7af3392e9d6ddad0397f1eeb6b91ed1107cc2
ToppCellP07-Epithelial-airway_epithelial_cell-club_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP70 SPAG17 MYB

5.52e-04184393ab469b9e06212462cbe2e4db8775c6778db855e6
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

CFAP70 SPAG17 MYB

5.61e-0418539330f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell15-Trachea-Epithelial-Multiciliated_precursor|Trachea / Age, Tissue, Lineage and Cell class

SPAG17 TRAF3IP1 MYB

5.61e-041853939a8b8360d99375b726ca8e3c9a3f9b08919892d7
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP70 SPAG17 MYB

5.61e-041853933e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellP28-Epithelial-airway_epithelial_cell-club_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP70 SPAG17 MYB

5.69e-04186393a26811481668fa25c48a064a56c198685693ad8d
ToppCellP28-Epithelial-airway_epithelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP70 SPAG17 MYB

5.69e-04186393df80f101954b8ec6ccdb03e702de22e70b65181f
ToppCellPND14-Epithelial-Epithelial_Airway|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1

5.78e-041873931399c703505211c510b3f14c7a2aa9930566c473
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ1A CREBBP GNL3

5.78e-04187393663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCellPND28-Epithelial-Epithelial_Airway|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPAG17 TRAF3IP1 HSP90AA1

5.78e-04187393f777dd5eb5ccd554ebe1ed60a738b5dd45e18bb9
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP70 SPAG17 MYB

5.78e-041873939e10ed56090d82589bc457788282f664b70ace4b
ToppCell21-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

CFAP70 SPAG17 TRAF3IP1

5.78e-041873931a2178a195d078d1963947b327c6d0d4f2f48341
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

CFAP70 SPAG17 MYB

5.87e-0418839334b11f72ca73153d02edcd09b38983ad1a504659
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

CFAP70 SPAG17 TRAF3IP1

5.87e-04188393606907c865bd2f11bb6474932716550f7723d858
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1

5.97e-0418939302c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPAG17 TRAF3IP1 HSP90AA1

5.97e-04189393fa1ff8b7fa53f3148d9117d6e598097f03af5eb2
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFAP70 SPAG17 MYB

5.97e-04189393a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1

5.97e-04189393164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCellPND10-Epithelial-Epithelial_Airway|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1

5.97e-04189393407d8a59969d83f014600aae1a55092283a13970
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP70 SPAG17 TRAF3IP1

5.97e-04189393cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPAG17 TRAF3IP1 HSP90AA1

5.97e-04189393565063f9e3dd79164321f8a394bd12c176baf202
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

CFAP70 SPAG17 MYB

5.97e-04189393b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

CFAP70 SPAG17 MYB

5.97e-0418939327329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPAG17 TRAF3IP1 HSP90AA1

5.97e-04189393497be236848ebf5ad75d1f0c71e6261f5d3521da
ToppCellHSPCs-Ery_prog.|HSPCs / Lineage and Cell class

NEFH GNL3 MYB

5.97e-0418939337d2c45debed1564a40a1085b8b310c50923b9e7
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1

6.06e-0419039335248a8be476ea8d06d67c3d98a25be1f7c150b7
ToppCellPND28-Epithelial|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPAG17 TRAF3IP1 HSP90AA1

6.06e-0419039389e5ddd830f70429d5b2fbaf8d0790b033450aa7
ToppCellEpithelial_cells-Ciliated_cells-A|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

CFAP70 SPAG17 MYB

6.06e-04190393549d813a8f23b175875e53347928941f143e236c
ToppCellE18.5-Epithelial-Epithelial_Airway|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 MYB

6.06e-041903935c012935ea5e35a2d0d08ea7dc04ffbe3c2a10ac
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-intestinal_crypt_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP70 GNL3 MYB

6.06e-0419039352c59001a079c76249abbaa3141e9e661b83d9a0
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1

6.06e-041903935f5206f9e725070d865f4c891ff08bb750e58582
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP70 SPAG17 TRAF3IP1

6.06e-04190393088e3f39a1e5e11354d6e7458e8e6a39f14936b3
ToppCellsevere_COVID-19-CD4+_T_naive|World / disease group, cell group and cell class (v2)

NAP1L3 TBC1D4 GNL3

6.15e-0419139355a282478488efd1561ea57a6f0218f55f711bb0
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated-diff|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPAG17 TRAF3IP1 HSP90AA1

6.15e-041913933e84c453e8a151c42808fe2935f1d732e180008c
ToppCellMyeloid-Myeloid-B_(Activated_Macrophage)|Myeloid / shred on cell class and cell subclass (v4)

UPF3B BAZ1A HSP90AA1

6.15e-041913937bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

PARD3B TCERG1 HSP90AA1

6.24e-04192393916fbec1c7ab7969bda711886ac88e877e30c280
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-Lgr5+_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GNL3 HSP90AA1 MYB

6.24e-041923935155f746ad57122ef735da776c96721005b8dadc
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-Tregs|lymph-node_spleen / Manually curated celltypes from each tissue

TBC1D4 HSP90AA1 MYB

6.24e-0419239391a4d06e8d1d1fe2ce5f72668108513bd2a72c4d
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

CFAP70 SPAG17 TRAF3IP1

6.24e-041923939cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNHIT6 BAZ1A GNL3

6.34e-04193393463274f394757fb2570ae885d58e1f9fa7e60c4a
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP70 SPAG17 TRAF3IP1

6.34e-04193393e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

PARD3B TCERG1 HSP90AA1

6.34e-04193393e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellHSPCs-Ery_prog.|World / Lineage and Cell class

NEFH GNL3 MYB

6.34e-04193393484c2e0daedc6cb0d50d164add8c1658123a60f9
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP70 SPAG17 TRAF3IP1

6.43e-041943934a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

PARD3B CFAP70 SPAG17

6.53e-04195393fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellnormal_Lung-Epithelial_cells-Ciliated|Epithelial_cells / Location, Cell class and cell subclass

CFAP70 SPAG17 HSP90AA1

6.53e-04195393a3e2999fdd4c3575add6e28ecfd1d6606a61f992
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A

CHD9 ZNHIT6 BAZ1A CREBBP MYB

1.09e-051823753887_DN
DrugICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A

CHD9 BAZ1A GNL3 MYB MYBL1

1.12e-051833756925_DN
DrugMeclocycline sulfosalicylate [73816-42-9]; Up 200; 5.8uM; MCF7; HT_HG-U133A

SAFB2 TRAF3IP1 RYR1 MYB MYBL1

1.57e-051963753277_UP
DrugC13932

THOC2 TCERG1 GNL3 RYR1 HSP90AA1

1.99e-05206375CID000168297
DiseaseCongenital myopathy (disorder)

RYR1 SCN4A

8.95e-0512352C0270960
DiseaseAdenoid Cystic Carcinoma

CREBBP MYB MYBL1

2.28e-04100353C0010606
Diseaseintrahepatic cholangiocarcinoma (is_marker_for)

PBRM1 HSP90AA1

2.31e-0419352DOID:4928 (is_marker_for)
Diseaseretinitis pigmentosa (implicated_via_orthology)

CNGB1 CWC27

4.71e-0427352DOID:10584 (implicated_via_orthology)
Diseaseglaucoma (biomarker_via_orthology)

NEFH HDAC1

5.07e-0428352DOID:1686 (biomarker_via_orthology)
DiseaseAmyotrophic Lateral Sclerosis, Sporadic

NEFH CREBBP

1.49e-0348352C1862941
DiseaseAmyotrophic Lateral Sclerosis, Familial

NEFH CREBBP

1.49e-0348352C4551993
Diseasemultiple sclerosis (is_marker_for)

NEFH HDAC1

1.55e-0349352DOID:2377 (is_marker_for)
Diseasealcohol use disorder (implicated_via_orthology)

PBRM1 CREBBP RYR1

1.59e-03195353DOID:1574 (implicated_via_orthology)
DiseaseAMYOTROPHIC LATERAL SCLEROSIS 1

NEFH CREBBP

1.62e-0350352C1862939

Protein segments in the cluster

PeptideGeneStartEntry
EDKEEEIIKEKEPPK

ABCF1

201

Q8NE71
EDPLFIIRKKEEEKK

CWC25

136

Q9NXE8
PREIKRLKKEKPEEE

CWC27

176

Q6UX04
KKPEVKVEVKEEEES

CREBBP

1051

Q92793
TEEEKDKKKEPHDVR

DHX29

351

Q7Z478
EKKREELKKIVEEER

BAZ1A

346

Q9NRL2
VEEERLKKKEEKERL

BAZ1A

356

Q9NRL2
RDESETEKEKIKKLP

RCC2

501

Q9P258
EDLERELKKEKPKHE

RBMX2

236

Q9Y388
VKEKKRKEENEDPER

PARD3B

851

Q8TEW8
DVEKERKEKLPKEIE

PBRM1

901

Q86U86
PKEIEEDKLKREEEK

PBRM1

911

Q86U86
EELKEDRKPREKDKD

TRAF3IP1

186

Q8TDR0
KRVKTEDEKEKDPEE

HDAC1

441

Q13547
KEGLELPEDEEEKKK

HSP90AB3P

411

Q58FF7
KEGLELPEDEEEKKK

HSP90AA5P

231

Q58FG0
DEDPEKEKRIKELEL

MYB

286

P10242
EDAKAPEKEIPKKEE

NEFH

811

P12036
KKIDRIPERDKLKDE

UPF3B

251

Q9BZI7
RLKEDVEKKLAPKEE

CHD9

1081

Q3L8U1
LKEDKPVKEKDIDGR

CFAP70

411

Q5T0N1
KVGEPEVKEEKVKEE

ZNHIT6

131

Q9NWK9
AHKKIPEEEKREEKL

ITGA10

1151

O75578
EKDIHEELPKRKERK

GNL3

466

Q9BVP2
KEGLELPEDEEEKKK

HSP90AA1

546

P07900
TPEKLKEEEVKEEGK

C4orf54

1231

D6RIA3
RLVKKKEEKPEEERS

RYR1

2071

P21817
PFIDEDPDKEKKIKE

MYBL1

256

P10243
DEEVKKLKDIKEIVP

TCP11L1

196

Q9NUJ3
PKEEVTVKKEKRERD

POLR3D

71

P05423
EDEKKEPPEEDLKKD

SCN4A

876

P35499
KEIPEVKDEEKEVPK

NAP1L3

211

Q99457
EIKKEPEKPIDREKT

SAP18

11

O00422
EKEKEKEKIPFILEG

SPAG17

921

Q6Q759
AEEALKEKEKPKEEE

SRRT

386

Q9BXP5
KERTEKVKEKLIDPD

CNGB1

576

Q14028
REKEKEKEEEKVEKP

THOC2

326

Q8NI27
KEKLEEKIKEPIKEP

TCERG1

466

O14776
EEKDIKPIIKDEKGR

SAFB2

386

Q14151
DPEKIEERKKSKELR

TBC1D4

826

O60343
EKRLTEEREKKDGKP

ZMAT2

26

Q96NC0