Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity	PDE3A PDE3B	5.76e-05	2	152	2	GO:0004119
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	TBX22 SP4 PDE3A CUX2 ZBTB38 FOXK2 ZNF628 FEZF2 DUX4L9 E2F7 POU2F1 DUX4L2 DUX4 SIX4 CIC FOXD3 BHLHE23 NFE2L1 RBPJ SIX5 PAX1 DUX4L4 EPAS1 ZNF292 NPAS1	6.36e-05	1412	152	25	GO:0000981
GeneOntologyCellularComponent	clathrin coat of trans-Golgi network vesicle	SYNRG CLTCL1 AP1B1 AP1G1	8.00e-06	18	154	4	GO:0030130
GeneOntologyCellularComponent	trans-Golgi network transport vesicle	SYNRG CLTCL1 IGF2R AP1B1 AP1G1	1.09e-05	40	154	5	GO:0030140
GeneOntologyCellularComponent	trans-Golgi network transport vesicle membrane	SYNRG CLTCL1 AP1B1 AP1G1	1.87e-05	22	154	4	GO:0012510
GeneOntologyCellularComponent	clathrin coat	SYNRG CLTCL1 IGF2R AP1B1 AP1G1	5.74e-05	56	154	5	GO:0030118
GeneOntologyCellularComponent	AP-1 adaptor complex	SYNRG AP1B1 AP1G1	8.22e-05	12	154	3	GO:0030121
GeneOntologyCellularComponent	membrane coat	SYNRG CLTCL1 IGF2R AP1B1 AP1G1 AP5B1	1.35e-04	106	154	6	GO:0030117
GeneOntologyCellularComponent	coated membrane	SYNRG CLTCL1 IGF2R AP1B1 AP1G1 AP5B1	1.35e-04	106	154	6	GO:0048475
GeneOntologyCellularComponent	MAML1-RBP-Jkappa- ICN1 complex	MAML1 RBPJ	1.61e-04	3	154	2	GO:0002193
GeneOntologyCellularComponent	clathrin vesicle coat	SYNRG CLTCL1 AP1B1 AP1G1	1.72e-04	38	154	4	GO:0030125
GeneOntologyCellularComponent	AP-type membrane coat adaptor complex	SYNRG AP1B1 AP1G1 AP5B1	4.28e-04	48	154	4	GO:0030119
GeneOntologyCellularComponent	chromatin	TBX22 SP4 CUX2 FOXK2 BICRA E2F7 POU2F1 SIX4 CIC GATAD2B YEATS2 FOXD3 BHLHE23 NFE2L1 ARID2 RBPJ SMARCC2 SIX5 PAX1 TAF4 SAP130 EPAS1 NPAS1	5.30e-04	1480	154	23	GO:0000785
GeneOntologyCellularComponent	Golgi-associated vesicle membrane	SYNRG CLTCL1 AP1B1 AP1G1	1.07e-03	61	154	4	GO:0030660
GeneOntologyCellularComponent	SWI/SNF complex	BICRA ARID2 SMARCC2	1.38e-03	30	154	3	GO:0016514
GeneOntologyCellularComponent	vesicle coat	SYNRG CLTCL1 AP1B1 AP1G1	1.51e-03	67	154	4	GO:0030120
GeneOntologyCellularComponent	clathrin adaptor complex	SYNRG AP1B1 AP1G1	1.51e-03	31	154	3	GO:0030131
GeneOntologyCellularComponent	Golgi-associated vesicle	SYNRG CLTCL1 IGF2R AP1B1 AP1G1	1.57e-03	114	154	5	GO:0005798
GeneOntologyCellularComponent	clathrin-coated vesicle	SYNRG CLTCL1 SCYL2 IGF2R AP1B1 AP1G1 HTT	1.91e-03	237	154	7	GO:0030136
Domain	ARM-type_fold	MON2 CLTCL1 CUL7 MEI1 RYR3 SCYL2 AP1B1 AP1G1 ARID2 TTC12 HTT	8.90e-05	339	149	11	IPR016024
Domain	Cul7	CUL7 HERC2	1.89e-04	3	149	2	PF11515
Domain	Ryanodine_rcpt	RYR2 RYR3	1.89e-04	3	149	2	IPR003032
Domain	CPH_domain	CUL7 HERC2	1.89e-04	3	149	2	IPR021097
Domain	Ryanrecept_TM4-6	RYR2 RYR3	1.89e-04	3	149	2	IPR009460
Domain	RyR	RYR2 RYR3	1.89e-04	3	149	2	PF02026
Domain	RR_TM4-6	RYR2 RYR3	1.89e-04	3	149	2	PF06459
Domain	Ryan_recept	RYR2 RYR3	1.89e-04	3	149	2	IPR013333
Domain	ARM-like	MON2 CUL7 MEI1 SCYL2 AP1B1 AP1G1 ARID2 TTC12 HTT	3.24e-04	270	149	9	IPR011989
Pubmed	Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element.	DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	8.19e-17	12	160	8	10433963
Pubmed	Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy.	DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	2.12e-16	13	160	8	17668377
Pubmed	The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	3.04e-16	8	160	7	17588759
Pubmed	DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	4.53e-15	10	160	7	17984056
Pubmed	Characterization of a tandemly repeated 3.3-kb KpnI unit in the facioscapulohumeral muscular dystrophy (FSHD) gene region on chromosome 4q35.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	6.41e-14	13	160	7	7739628
Pubmed	Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	7.15e-13	17	160	7	11245978
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	SP4 FOXK2 SPR BICRA CASP1 MAML1 POU2F1 ZNF318 PRC1 RRM1 AHDC1 CIC GATAD2B YEATS2 AP1B1 ARID2 MIF SMARCC2 TAF4 SAP130 CNOT1 NUP153 ZNF292	1.58e-09	1103	160	23	34189442
Pubmed	Interaction network of human early embryonic transcription factors.	FOXK2 BICRA MAML1 POU2F1 PROSER1 NUP214 SIX4 AHDC1 ARID2 SMARCC2 TAF4 PRDM6	9.37e-08	351	160	12	38297188
Pubmed	A census of human transcription factors: function, expression and evolution.	TBX22 SP4 CUX2 ZBTB38 FOXK2 E2F7 POU2F1 SIX4 CIC YEATS2 FOXD3 BHLHE23 NFE2L1 RBPJ SIX5 PAX1 EPAS1 NPAS1	2.28e-07	908	160	18	19274049
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	FOXK2 BICRA MAML1 E2F7 SIX4 GATAD2B YEATS2 ARID2 RBPJ SMARCC2 SIX5 ZNF292	3.60e-07	398	160	12	35016035
Pubmed	Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development.	DUX4L9 DUX4L2 DUX4L4	3.81e-07	4	160	3	17911620
Pubmed	The homeobox transcription factor DUXBL controls exit from totipotency.	DUX4L9 DUX4L2 DUX4L4	3.81e-07	4	160	3	38509386
Pubmed	Proteomic analysis identifies transcriptional cofactors and homeobox transcription factors as TBX18 binding proteins.	DUX4L9 DUX4L2 PAX1 DUX4L4	5.66e-07	15	160	4	30071041
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MON2 DPH2 SYNRG FOXK2 CLTCL1 ZNF628 BICRA MAML1 ANKLE1 NUP214 TESK1 AHDC1 CIC IGF2R SBF1 HERC2 WNK2 HTT RBM38	8.84e-07	1105	160	19	35748872
Pubmed	Characterization of genomic structures and expression profiles of three tandem repeats of a mouse double homeobox gene: Duxbl.	DUX4L9 DUX4L2 DUX4L4	9.49e-07	5	160	3	20063414
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	MAML1 LRRC70 NRROS CIC RYR2 YEATS2 OSBP RNF123 EXD3 AP1B1 ARID2 SMARCC2 TIGD5 CNOT1	1.68e-06	638	160	14	31182584
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	ZNF318 NUP214 RYR2 YEATS2 CNOT1 NUP153 ZNF292	1.74e-06	123	160	7	26912792
Pubmed	Human transcription factor protein interaction networks.	FOXK2 SCAF8 BICRA MAML1 POU2F1 PROSER1 ZNF318 NUP214 SIX4 CUL7 CIC GATAD2B YEATS2 ARID2 RBPJ SMARCC2 SIX5 TAF4 HERC2 SAP130 CNOT1	2.75e-06	1429	160	21	35140242
Pubmed	The transcription factor Duxbl mediates elimination of pre-T cells that fail β-selection.	DUX4L9 DUX4L2 DUX4L4	3.30e-06	7	160	3	30765463
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PDE3B TUT4 FOXK2 SCAF8 BICRA WDR27 AHDC1 DNAH14 YEATS2 EXD3 GPR158 SLC19A1 PLEKHG3 TTC12 WDR45B TAF4 METTL15 SAP130 CNOT1 WNK2 HTT	5.19e-06	1489	160	21	28611215
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	SP4 CUX2 DUX4L9 POU2F1 DUX4L2 ZNF318 SIX4 CIC GATAD2B NFE2L1 ARID2 RBPJ DUX4L4 EPAS1 ZNF292	5.41e-06	808	160	15	20412781
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SP4 CUX2 BICRA NUP214 CIC NFE2L1 AP5B1 ARID2 SAP130 WNK2 NUP153	5.42e-06	430	160	11	35044719
Pubmed	EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking.	SYNRG AP1B1 AP1G1	7.87e-06	9	160	3	12538641
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	FOXK2 SPR SCAF8 MAML1 NUP214 AHDC1 CIC YEATS2 SAP130 CNOT1 NUP153	9.60e-06	457	160	11	32344865
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	FOXK2 SIX4 RRM1 CIC SBSN SCYL2 YEATS2 IGF2R AP1G1 ARID2 SAP130	1.30e-05	472	160	11	38943005
Pubmed	A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome.	SYNRG AP1B1 AP1G1	1.53e-05	11	160	3	10747088
Pubmed	Co-inheritance of the membrane frizzled-related protein ocular phenotype and glycogen storage disease type Ib.	MFRP SLC37A4	2.10e-05	2	160	2	28511025
Pubmed	The human papillomavirus type 8 E6 protein interferes with NOTCH activation during keratinocyte differentiation.	MAML1 RBPJ	2.10e-05	2	160	2	23365452
Pubmed	CBF-1 Promotes the Establishment and Maintenance of HIV Latency by Recruiting Polycomb Repressive Complexes, PRC1 and PRC2, at HIV LTR.	PRC1 RBPJ	2.10e-05	2	160	2	32961937
Pubmed	A pathophysiological role of PDE3 in allergic airway inflammation.	PDE3A PDE3B	2.10e-05	2	160	2	29367458
Pubmed	Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.	RYR2 RYR3	2.10e-05	2	160	2	8898078
Pubmed	Distinct transcriptional signature and immunoprofile of CIC-DUX4 fusion-positive round cell tumors compared to EWSR1-rearranged Ewing sarcomas: further evidence toward distinct pathologic entities.	DUX4 CIC	2.10e-05	2	160	2	24723486
Pubmed	Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease.	CASP1 HTT	2.10e-05	2	160	2	10353249
Pubmed	The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.	RYR2 RYR3	2.10e-05	2	160	2	14550562
Pubmed	Defective regulation of microRNA target genes in myoblasts from facioscapulohumeral dystrophy patients.	DUX4L9 DUX4	2.10e-05	2	160	2	24145033
Pubmed	Expanding the differential of superficial tumors with round-cell morphology: Report of three cases of CIC-rearranged sarcoma, a potentially under-recognized entity.	DUX4 CIC	2.10e-05	2	160	2	31886887
Pubmed	Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice.	PDE3A PDE3B	2.10e-05	2	160	2	17482796
Pubmed	Primary undifferentiated small round cell sarcoma of the deep abdominal wall with a novel variant of t(10;19) CIC-DUX4 gene fusion.	DUX4 CIC	2.10e-05	2	160	2	28645808
Pubmed	CIC-DUX4 fusion-positive round-cell sarcomas of soft tissue and bone: a single-institution morphological and molecular analysis of seven cases.	DUX4 CIC	2.10e-05	2	160	2	27079694
Pubmed	Targeted disruption of PDE3B, but not PDE3A, protects murine heart from ischemia/reperfusion injury.	PDE3A PDE3B	2.10e-05	2	160	2	25877153
Pubmed	Role of defective calcium regulation in cardiorespiratory dysfunction in Huntington's disease.	RYR2 HTT	2.10e-05	2	160	2	32897880
Pubmed	Targeted next-generation sequencing of CIC-DUX4 soft tissue sarcomas demonstrates low mutational burden and recurrent chromosome 1p loss.	DUX4 CIC	2.10e-05	2	160	2	27664537
Pubmed	Expression of three zebrafish Six4 genes in the cranial sensory placodes and the developing somites.	SIX4 SIX5	2.10e-05	2	160	2	11044620
Pubmed	Phosphodiesterase type 3A (PDE3A), but not type 3B (PDE3B), contributes to the adverse cardiac remodeling induced by pressure overload.	PDE3A PDE3B	2.10e-05	2	160	2	31051182
Pubmed	Basolateral sorting of chloride channel 2 is mediated by interactions between a dileucine motif and the clathrin adaptor AP-1.	CLCN2 AP1B1	2.10e-05	2	160	2	25739457
Pubmed	Pde3a and Pde3b regulation of murine pulmonary artery smooth muscle cell growth and metabolism.	PDE3A PDE3B	2.10e-05	2	160	2	39435735
Pubmed	Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.	RYR2 RYR3	2.10e-05	2	160	2	21531043
Pubmed	Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.	RYR2 RYR3	2.10e-05	2	160	2	16678258
Pubmed	Clinicopathologic features of undifferentiated round cell sarcomas of bone & soft tissues: An attempt to unravel the BCOR-CCNB3- & CIC-DUX4-positive sarcomas.	DUX4 CIC	2.10e-05	2	160	2	32048619
Pubmed	Gamma-adaptin appendage domain: structure and binding site for Eps15 and gamma-synergin.	SYNRG AP1G1	2.10e-05	2	160	2	12176391
Pubmed	Sarcomas With CIC-rearrangements Are a Distinct Pathologic Entity With Aggressive Outcome: A Clinicopathologic and Molecular Study of 115 Cases.	DUX4 CIC	2.10e-05	2	160	2	28346326
Pubmed	Phosphodiesterase 3A (PDE3A) deletion suppresses proliferation of cultured murine vascular smooth muscle cells (VSMCs) via inhibition of mitogen-activated protein kinase (MAPK) signaling and alterations in critical cell cycle regulatory proteins.	PDE3A PDE3B	2.10e-05	2	160	2	21632535
Pubmed	Cytomorphological features and literature review of CIC-DUX4-positive sarcoma, confirmed by reverse transcription polymerase chain reaction in a paediatric patient.	DUX4 CIC	2.10e-05	2	160	2	33399252
Pubmed	Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.	RYR2 RYR3	2.10e-05	2	160	2	14985349
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	SCAF8 TTLL5 ZNF318 GATAD2B SBSN SCYL2 YEATS2	2.44e-05	184	160	7	32908313
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	CUX2 FOXK2 POU2F1 ZNF318 SIX4 CIC FOXD3 NFE2L1 SIX5 PAX1 TIGD5 EPAS1 ZNF292	2.66e-05	709	160	13	22988430
Pubmed	NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.	CARMIL2 MAML1 GATAD2B RBPJ SMARCC2 CNOT1	3.08e-05	129	160	6	23022380
Pubmed	Mouse model resources for vision research.	MFRP CLCN2 PAX1 MERTK	3.83e-05	41	160	4	21052544
Pubmed	Mutations in MINAR2 encoding membrane integral NOTCH2-associated receptor 2 cause deafness in humans and mice.	DUX4L9 DUX4L2 DUX4L4	4.17e-05	15	160	3	35727972
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	POU2F1 SIX4 CIC SAP130 ZNF292	4.21e-05	83	160	5	28794006
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXK2 MAML1 POU2F1 SIX4 CUL7 PRC1 CIC GATAD2B FOXD3 RBPJ SMARCC2 SIX5 SAP130 PRDM6	4.56e-05	857	160	14	25609649
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZSWIM8 TTLL5 CIC GPR158 ZNF292	5.28e-05	87	160	5	12465718
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	SYNRG DMXL2 TESK1 SCYL2 IGF2R AP1B1 AP1G1 HTT	5.61e-05	285	160	8	34369648
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MON2 ZSWIM8 TUT4 FEZF2 BICRA BIRC2 ZNF318 CUL7 GATAD2B YEATS2 ARID2 SMARCC2 TIGD5 TAF4 SAP130 ALG13	6.13e-05	1116	160	16	31753913
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR2 RYR3	6.29e-05	3	160	2	18403125
Pubmed	Structural basis for the accessory protein recruitment by the gamma-adaptin ear domain.	SYNRG AP1G1	6.29e-05	3	160	2	12042876
Pubmed	A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters.	MAML1 RBPJ	6.29e-05	3	160	2	11390662
Pubmed	Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.	RYR2 RYR3	6.29e-05	3	160	2	29730765
Pubmed	Molecular cloning and chromosomal assignment of the human homologue of the rat cGMP-inhibited phosphodiesterase 1 (PDE3A)--a gene involved in fat metabolism located at 11p 15.1.	PDE3A PDE3B	6.29e-05	3	160	2	8921398
Pubmed	The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.	RYR2 RYR3	6.29e-05	3	160	2	7876312
Pubmed	Multiple tumor-suppressor genes on chromosome 3p contribute to head and neck squamous cell carcinoma tumorigenesis.	XIRP1 EPHA3	6.29e-05	3	160	2	20657180
Pubmed	Direct inhibition of the NOTCH transcription factor complex.	MAML1 RBPJ	6.29e-05	3	160	2	19907488
Pubmed	Low Six4 and Six5 gene dosage improves dystrophic phenotype and prolongs life span of mdx mice.	SIX4 SIX5	6.29e-05	3	160	2	27224259
Pubmed	Apoptosis. Dead end for neurodegeneration?	CASP1 HTT	6.29e-05	3	160	2	10353238
Pubmed	Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.	RYR2 RYR3	6.29e-05	3	160	2	22948152
Pubmed	Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 Rev.	NUP214 NUP153	6.29e-05	3	160	2	9847314
Pubmed	Mutational and energetic studies of Notch 1 transcription complexes.	MAML1 RBPJ	6.29e-05	3	160	2	18155729
Pubmed	Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.	RYR2 RYR3	6.29e-05	3	160	2	10788707
Pubmed	Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.	RYR2 RYR3	6.29e-05	3	160	2	7621815
Pubmed	Quantitative proteomic identification of six4 as the trex-binding factor in the muscle creatine kinase enhancer.	SIX4 SIX5	6.29e-05	3	160	2	14966291
Pubmed	Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex.	MAML1 RBPJ	6.29e-05	3	160	2	12644465
Pubmed	Detailed cytogenetic and array analysis of pediatric primitive sarcomas reveals a recurrent CIC-DUX4 fusion gene event.	DUX4 CIC	6.29e-05	3	160	2	19837261
Pubmed	Molecular identification of the ryanodine receptor pore-forming segment.	RYR2 RYR3	6.29e-05	3	160	2	10473538
Pubmed	Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease.	TAF4 HTT	6.29e-05	3	160	2	11988536
Pubmed	Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus.	NUP214 NUP153	6.29e-05	3	160	2	12191473
Pubmed	Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.	RYR2 RYR3	6.29e-05	3	160	2	18434746
Pubmed	SPRY domains in ryanodine receptors (Ca(2+)-release channels).	RYR2 RYR3	6.29e-05	3	160	2	9204703
Pubmed	Endothelial progenitor cell homing: prominent role of the IGF2-IGF2R-PLCbeta2 axis.	IGF2R PLCB2	6.29e-05	3	160	2	18832656
Pubmed	Conformational locking upon cooperative assembly of notch transcription complexes.	MAML1 RBPJ	6.29e-05	3	160	2	22325781
Pubmed	Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.	RYR2 RYR3	6.29e-05	3	160	2	21881589
Pubmed	Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).	RYR2 RYR3	6.29e-05	3	160	2	12213830
Pubmed	Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.	RYR2 RYR3	6.29e-05	3	160	2	9242641
Pubmed	RYR2 proteins contribute to the formation of Ca(2+) sparks in smooth muscle.	RYR2 RYR3	6.29e-05	3	160	2	15024040
Pubmed	Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.	MAML1 RBPJ	6.29e-05	3	160	2	16530044
Pubmed	Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.	RYR2 RYR3	6.29e-05	3	160	2	25239916
Pubmed	Unraveling the role of hypoxia-inducible factor (HIF)-1α and HIF-2α in the adaption process of human microvascular endothelial cells (HMEC-1) to hypoxia: Redundant HIF-dependent regulation of macrophage migration inhibitory factor.	MIF EPAS1	6.29e-05	3	160	2	28993199
Pubmed	A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.	RYR2 RYR3	6.29e-05	3	160	2	18643873
Pubmed	Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).	RYR2 RYR3	6.29e-05	3	160	2	11159936
Pubmed	The nuclear pore complex: a new dynamic in HIV-1 replication.	NUP214 NUP153	6.29e-05	3	160	2	21327100
Pubmed	Impact of phosphodiesterases PDE3 and PDE4 on 5-hydroxytryptamine receptor4-mediated increase of cAMP in human atrial fibrillation.	PDE3A PDE3B	6.29e-05	3	160	2	32949251
Interaction	SP7 interactions	SCAF8 BICRA MAML1 POU2F1 PROSER1 ZNF318 SIX4 CIC RNF123 ARID2 SMARCC2 SAP130	3.24e-06	304	151	12	int:SP7
Interaction	NFIX interactions	FOXK2 BICRA POU2F1 SIX4 CIC ARID2 RBPJ SMARCC2 TAF4 SAP130	8.46e-06	227	151	10	int:NFIX
Interaction	NUP35 interactions	FOXK2 SPR SCAF8 MAML1 NUP214 CUL7 PRC1 AHDC1 CIC YEATS2 SAP130 CNOT1 NUP153	1.91e-05	424	151	13	int:NUP35
Interaction	TFAP4 interactions	FOXK2 CIC YEATS2 ARID2 RBPJ SMARCC2 WDR45B SAP130	2.04e-05	153	151	8	int:TFAP4
Interaction	TLE3 interactions	SCAF8 MAML1 PROSER1 ZNF318 SIX4 AHDC1 CIC ARID2 SMARCC2 TAF4 SAP130 ALG13	2.73e-05	376	151	12	int:TLE3
Cytoband	4q35.2	DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	4.54e-10	27	160	6	4q35.2
Cytoband	Ensembl 112 genes in cytogenetic band chr4q35	DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	9.02e-09	117	160	8	chr4q35
GeneFamily	PRD class homeoboxes and pseudogenes	DUX4L9 DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	1.85e-06	92	114	7	521
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR2 RYR3	1.18e-04	3	114	2	287
GeneFamily	SINE class homeoboxes	SIX4 SIX5	5.81e-04	6	114	2	525
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 PRLHR COL15A1 PCDHGA6 C8orf74 PLCB2 WNK2 RBM38	2.05e-07	178	154	8	09a215a0d6e98e4bb920cabda12af08ff4de3c98
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Hpgd\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TBX22 KLHL1 FEZF2 ACY3 C8orf74 LRG1 RYR3	2.88e-07	126	154	7	9b04ca8a46cc30119baf6ef27711a0b2a6b4a0c9
Drug	PCB 66	ACY3 RYR2 RYR3 DECR1	7.09e-07	11	158	4	CID000036185
Drug	EMD 60263	PDE3A PDE3B DSG3	6.46e-06	6	158	3	CID000187063
Drug	AC1N9ZZC	FOXK2 CLTCL1 GATM SIX4 RYR2 RYR3 SIX5 RBM38	9.80e-06	149	158	8	CID004369374
Drug	Disopyramide [3737-09-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A	ZSWIM8 DMXL2 ZNF318 CIC CD6 CLCN2 SBF1 SLC19A1 SMARCC2	1.09e-05	199	158	9	7439_UP
Drug	Nimodipine [66085-59-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A	ZSWIM8 CTSF TTLL5 CASP1 AHDC1 CIC RYR2 EXD3 CLCN2	1.09e-05	199	158	9	5421_DN
Drug	Atropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; MCF7; HT_HG-U133A	BICRA SIK1 ZNF318 TESK1 CIC RYR2 SBF1 AP1B1 ZNF292	1.09e-05	199	158	9	7219_DN
Drug	BCNU	CUX2 CLTCL1 TTLL5 GATM ISLR PRC1 DECR1 MERTK NPAS1	3.30e-05	229	158	9	CID000002578
Drug	diacetone acrylamide	NUP214 DECR1	4.79e-05	2	158	2	CID000017888
Drug	Inocor (TN)	PDE3A PDE3B	4.79e-05	2	158	2	CID000656683
Drug	RS-1893	PDE3A PDE3B	4.79e-05	2	158	2	CID000128386
Drug	MCI-154	PDE3A PDE3B DSG3	5.19e-05	11	158	3	CID000123941
Drug	M-HN	PDE3A PDE3B RYR2 RYR3	6.07e-05	31	158	4	CID000015450
Drug	chlorpromazine hydrochloride; Down 200; 1uM; PC3; HT_HG-U133A	CASP1 NUP214 AHDC1 BTN2A2 SBF1 SLC19A1 PLEKHG3 SMARCC2	6.51e-05	194	158	8	1217_DN
Drug	Methoxy-6-harmalan [3589-73-9]; Down 200; 18.6uM; MCF7; HT_HG-U133A	ZSWIM8 CTSF TTLL5 MAML1 CUL7 BTN2A2 EXD3 SBF1	6.75e-05	195	158	8	5455_DN
Drug	Phenylpropanolamine hydrochloride [154-41-6]; Down 200; 21.4uM; HL60; HG-U133A	SYNRG CLTCL1 TTLL5 CIC BTN2A2 THBS4 PLCB2 ALG13	7.25e-05	197	158	8	1602_DN
Drug	Cinnarizine [298-57-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A	ZSWIM8 BICRA CASP1 ZNF318 RNF123 RBPJ SMARCC2 ALG13	7.51e-05	198	158	8	7174_DN
Drug	Nitrendipine [39562-70-4]; Down 200; 11uM; MCF7; HT_HG-U133A	CTSF TTLL5 SIK1 AHDC1 CIC RYR2 SBF1 MERTK	7.51e-05	198	158	8	5405_DN
Drug	Griseofulvin [126-07-8]; Up 200; 11.2uM; PC3; HT_HG-U133A	ZSWIM8 CASP1 NUP214 TESK1 RYR2 SLC22A14 EPAS1 EPHA3	7.78e-05	199	158	8	7363_UP
Drug	Clenbuterol hydrochloride [21898-19-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A	CACNB1 DMXL2 CTSF TTLL5 MAML1 GATM SBF1 PLCB2	7.78e-05	199	158	8	5266_UP
Drug	Triamcinolone [124-94-7]; Down 200; 10.2uM; MCF7; HT_HG-U133A	ZSWIM8 SIK1 ZNF318 RNF123 IGF2R SBF1 SMARCC2 HTT	7.78e-05	199	158	8	7192_DN
Drug	Minocycline hydrochloride [13614-98-7]; Up 200; 8uM; MCF7; HT_HG-U133A	TRPM6 SYNRG CTSF PDE3B CASP1 SBF1 SLC22A14 SLC19A1	8.05e-05	200	158	8	7436_UP
Drug	Strophanthidin [66-28-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A	ZSWIM8 TTLL5 CUL7 AHDC1 CIC RNF123 PLEKHG3 ROM1	8.05e-05	200	158	8	7182_DN
Drug	SureCN4406168	PDE3A PDE3B	1.43e-04	3	158	2	CID011502028
Drug	SureCN4395097	PDE3A PDE3B	1.43e-04	3	158	2	CID011610011
Drug	SureCN4401117	PDE3A PDE3B	1.43e-04	3	158	2	CID011718172
Drug	SureCN4402206	PDE3A PDE3B	1.43e-04	3	158	2	CID011516917
Drug	WIN 62582	PDE3A PDE3B	1.43e-04	3	158	2	CID005487388
Drug	SureCN4397066	PDE3A PDE3B	1.43e-04	3	158	2	CID011538627
Drug	SureCN4401121	PDE3A PDE3B	1.43e-04	3	158	2	CID011611819
Drug	cis-diammineplatinum(II	RYR2 RYR3	1.43e-04	3	158	2	CID000159790
Drug	SureCN4404748	PDE3A PDE3B	1.43e-04	3	158	2	CID011502895
Drug	2-hydroxyheptanoic acid	RYR2 RYR3	1.43e-04	3	158	2	CID002750949
Drug	SureCN4411688	PDE3A PDE3B	1.43e-04	3	158	2	CID011523192
Drug	8N3-cADPR	RYR2 RYR3	1.43e-04	3	158	2	CID000127713
Drug	MA144-M1	DECR1 RBPJ	1.43e-04	3	158	2	CID000152638
Drug	aminodantrolene	RYR2 RYR3	1.43e-04	3	158	2	CID009570289
Drug	SureCN4405038	PDE3A PDE3B	1.43e-04	3	158	2	CID011546172
Drug	SureCN4405912	PDE3A PDE3B	1.43e-04	3	158	2	CID011682920
Drug	pelrinone	PDE3A PDE3B	1.43e-04	3	158	2	CID000055919
Drug	SureCN4398032	PDE3A PDE3B	1.43e-04	3	158	2	CID011532088
Drug	2-hydroxycarbazole	RYR2 RYR3	1.43e-04	3	158	2	CID000093551
Drug	SureCN4406373	PDE3A PDE3B	1.43e-04	3	158	2	CID011711104
Drug	SureCN4394894	PDE3A PDE3B	1.43e-04	3	158	2	CID011711103
Drug	SureCN5995113	PDE3A PDE3B	1.43e-04	3	158	2	CID011640499
Drug	CHEMBL219123	PDE3A PDE3B	1.43e-04	3	158	2	CID016102624
Drug	germitrine	PDE3A PDE3B	1.43e-04	3	158	2	CID000011217
Drug	SureCN4411840	PDE3A PDE3B	1.43e-04	3	158	2	CID011567407
Drug	SureCN4401113	PDE3A PDE3B	1.43e-04	3	158	2	CID011544858
Drug	Ryanodyl 3-(pyridine-3-carboxylate	RYR2 RYR3	1.43e-04	3	158	2	CID005748312
Drug	SureCN4405883	PDE3A PDE3B	1.43e-04	3	158	2	CID011516351
Drug	SureCN4407211	PDE3A PDE3B	1.43e-04	3	158	2	CID011553351
Drug	SureCN4401096	PDE3A PDE3B	1.43e-04	3	158	2	CID011710801
Disease	childhood onset asthma, age at onset	KLHL1 MACROD2	2.50e-05	2	148	2	EFO_0004847, MONDO_0005405
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR2 RYR3	7.47e-05	3	148	2	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR2 RYR3	7.47e-05	3	148	2	DOID:8545 (implicated_via_orthology)
Disease	susceptibility to rheumatic fever measurement	KLHL1 MAML1 RYR3	3.69e-04	28	148	3	EFO_0008416
Disease	childhood onset asthma, age at onset, environmental tobacco smoke exposure measurement	KLHL1 MACROD2	3.70e-04	6	148	2	EFO_0004847, EFO_0008361, MONDO_0005405
Disease	myotonic dystrophy type 1 (implicated_via_orthology)	SIX4 SIX5	3.70e-04	6	148	2	DOID:11722 (implicated_via_orthology)
Disease	Intellectual Disability	CUX2 SPR CIC AP1B1 SMARCC2 WDR45B HTT ZNF292 ALG13	4.45e-04	447	148	9	C3714756
Disease	Epileptic encephalopathy	NUP214 RYR3 ALG13	4.55e-04	30	148	3	C0543888
Disease	alcohol use disorder (implicated_via_orthology)	PRLHR RYR2 RYR3 ARID2 RBPJ SMARCC2	4.67e-04	195	148	6	DOID:1574 (implicated_via_orthology)
Disease	branchiootorenal syndrome (implicated_via_orthology)	SIX4 SIX5	5.16e-04	7	148	2	DOID:14702 (implicated_via_orthology)
Disease	white matter volume measurement	CIC GPR158 ZNF292	5.51e-04	32	148	3	EFO_0008320
Disease	citrate measurement	CLTCL1 IGF2R CNOT1 WNK2	6.82e-04	79	148	4	EFO_0010114
Disease	advanced glycation end-product measurement, type 2 diabetes mellitus	ZBTB38 MACROD2	6.86e-04	8	148	2	EFO_0007819, MONDO_0005148
Disease	pulmonary hypertension (biomarker_via_orthology)	PDE3A RYR2 RYR3 EPAS1	7.15e-04	80	148	4	DOID:6432 (biomarker_via_orthology)
Disease	cup-to-disc ratio measurement, optic cup area measurement, optic disc area measurement	SERPINE3 PLEKHG3	1.10e-03	10	148	2	EFO_0006937, EFO_0006939, EFO_0006940
Disease	Hyperhomocysteinemia	NPHS1 CASP1	1.33e-03	11	148	2	C0598608
Disease	Multiple Sclerosis	CASP1 CD6 RBPJ	1.50e-03	45	148	3	C0026769
Disease	Multiple Sclerosis, Acute Fulminating	CASP1 CD6 RBPJ	1.50e-03	45	148	3	C0751324
Disease	chronic musculoskeletal pain	RNF123 EXD3	1.60e-03	12	148	2	EFO_0022195
Disease	rhinitis (is_marker_for)	CASP1 MIF CCL7	1.60e-03	46	148	3	DOID:4483 (is_marker_for)
Disease	gamma-glutamylleucine measurement	CUX2 NLN	1.88e-03	13	148	2	EFO_0021140
Disease	Coffin-Siris syndrome	ARID2 SMARCC2	1.88e-03	13	148	2	C0265338
Disease	L2 Acute Lymphoblastic Leukemia	DUX4 NUP214 SLC19A1	2.04e-03	50	148	3	C0023453
Disease	Childhood Acute Lymphoblastic Leukemia	DUX4 NUP214 SLC19A1	2.28e-03	52	148	3	C0023452
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	DUX4 NUP214 SLC19A1	3.60e-03	61	148	3	C1961102
Disease	syndrome (implicated_via_orthology)	SCAF8 CNOT1	3.63e-03	18	148	2	DOID:225 (implicated_via_orthology)
Disease	Adenocarcinoma of lung (disorder)	TRPM6 RRM1 SCYL2 SLC19A1 EPHA3	3.90e-03	206	148	5	C0152013
Disease	Eczema, allergic rhinitis	ZBTB38 COL15A1 NRROS CD6 AP5B1	4.67e-03	215	148	5	EFO_0005854, HP_0000964
Disease	kidney disease (biomarker_via_orthology)	GATM MIF	4.93e-03	21	148	2	DOID:557 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
AGSLPAFTVPQAAAP	EPAS1	451	Q99814
AAINANGLIATPITP	CELF3	241	Q5SZQ8
AATPVSAIPAALGVN	CELF3	266	Q5SZQ8
NALTGLPPGLFQASA	LRG1	126	P02750
ANNVPAPVLSNGAAA	ALG13	856	Q9NP73
FSAVPVLANPAATSG	ACY3	46	Q96HD9
QRGVAPFQALSPSAG	CCDC187	961	A0A096LP49
QALTLTPPNAAGFQS	ANKLE1	276	Q8NAG6
SLQKAFAAAAPAQPG	C8orf74	196	Q6P047
AALAASPAPVSNLQG	CACNB1	431	Q02641
AFVSQAARAAPALQP	DUX4L4	206	P0CJ87
APVNAAPLTPFGQAT	BHLHE23	176	Q8NDY6
GVANSLPPQLFAAVS	CARMIL2	411	Q6F5E8
LIQQSSSPAAEGPAA	C2orf27A	136	P0DPF5
PPGLITNFSLATAEQ	GPR17	36	Q13304
IVLANPAALPAGQTV	ARID2	946	Q68CP9
SPALLAGTNPVAVVA	ANKRD13C	91	Q8N6S4
LAPQLSGSFFQPILA	DPH2	346	Q9BQC3
GTNFVAPPTAAVPAN	AP1B1	676	Q10567
PATDIPNVLVGTAFN	DMXL2	366	Q8TDJ6
AFVSQAARAAPALQP	DUX4L6	206	P0CJ89
GADPSFQPVLSARQT	AHDC1	906	Q5TGY3
PSLATASQNGAPALV	CUX2	731	O14529
TNLTGLFFPPQLNGT	NFE2L1	411	Q14494
VPQALSAAAPAGTTF	RBM38	211	Q9H0Z9
TAILQSFSLQPLGAP	CYP2F1	451	P24903
GQTPLDAFQLPASVA	NPAS1	411	Q99742
LSSQPLFNDIAAGIP	AP1G1	691	O43747
NLELAGTQPAFSAGP	CD6	601	P30203
AIILAQLQAAPPSGA	MFRP	86	Q9BY79
PSTAGFDPLLTQNVI	DSG3	946	P32926
AAAVGSLLPPVSAQQ	MAML1	896	Q92585
GQLSASTQLAVQFPP	NPHS1	531	O60500
LPVSVSANPAPEAFN	NPHS1	666	O60500
QFQVSARDAGVPPLS	PCDHA11	531	Q9Y5I1
IAESAPPGTVIALFQ	PCDHGA6	356	Q9Y5G7
PQAGLSQANFTLSPV	LILRA4	271	P59901
EGFPQSVLQIPVSAA	MAGEC1	156	O60732
AFVSQAARAAPALQP	DUX4	206	Q9UBX2
GAPSVAPLNVTVFLN	MERTK	381	Q12866
ATFNIIGPGIVLSNP	GATM	306	P50440
IQEARFAQSAPGSPL	FOXK2	416	Q01167
FETPAQPNAGRSVAL	GPR158	1176	Q5T848
LPFTVPSASGQDIQL	HERC2	4601	O95714
PRAPANIQVSFDSGA	FNDC7	201	Q5VTL7
AFVSQAARAAPALQP	DUX4L3	206	P0CJ86
PGFPANVTTLSLSAN	ISLR	46	O14498
PGRTNAFLVATSAPQ	PDE3A	841	Q14432
PGRTNAFLVATNAPQ	PDE3B	826	Q13370
FQPQLADVSPGLPAA	CUL7	331	Q14999
PVLAQPAVSNSGTAA	NUP214	1541	P35658
GNTVPAVFAIPAANR	KIAA1549L	1706	Q6ZVL6
VNTNVPRASVPDGFL	MIF	6	P14174
GFVPASEQRPLQATA	AP5B1	136	Q2VPB7
SNFAQAPQLSVPGGL	GATAD2B	531	Q8WXI9
NALGSFIQSLFLVPP	MON2	391	Q7Z3U7
GAAALVPTAITPFLN	OR10G3	271	Q8NGC4
TQQLASIVAGAFPPS	METTL15	251	A6NJ78
AFRGATVLPANTPGN	OSBP	321	P22059
AFGNPLETTAVLPVQ	LRRC70	471	Q7Z2Q7
FANAGGAPNIVTAPL	POU2F1	661	P14859
VEPQNPVLSAGGSLF	ICAM3	36	P32942
AGQPALPASLVVLFQ	MEI1	821	Q5TIA1
FSSALVALVPSGAQP	MEI1	1071	Q5TIA1
TPTPFIIGVNAAFQA	SBF1	281	O95248
TIAPSAYNNAGLVPL	PROSER1	211	Q86XN7
AGLSALPVSQLPVFA	PRDM6	106	Q9NQX0
VNRTAFPATPAVNGL	PAX1	326	P15863
PTEFVLAGLPNLNSA	OR6S1	11	Q8NH40
AGNFISPTERLSPNA	DECR1	146	Q16698
IALFGVIANESAPPN	SLC37A4	346	O43826
AFQSVLEVVAAPGSP	HTT	3111	P42858
GVLSSFPAPQAVQDN	CASP1	106	P29466
TLGALPNTGPVNFSL	E2F7	771	Q96AV8
AFVSQAARAAPALQP	DUX4L9	206	Q6RFH8
GAVAAPAQPRAASFQ	CTSF	16	Q9UBX1
AFVSQAARAAPALQP	DUX4L7	206	P0CJ90
AVNGVSELSSPPRQF	EPHA3	411	P29320
NAPFPLLDAVGSVAS	DNAH14	46	Q0VDD8
ASNGVFVVIPPNNAS	MS4A15	6	Q8N5U1
VGFILLSVNPAALNP	MS4A6E	66	Q96DS6
FAVPPALGSNLTDNV	MARCHF7	486	Q9H992
VFDLSGPSSLAQPVQ	IL22RA1	286	Q8N6P7
FFTQRLPVIAQGPAS	SLC44A5	631	Q8NCS7
LLTAAAFSPQGLAQP	CCL7	11	P80098
AASPAFLGQGQVPLN	ESRG	181	Q1W209
AFVSQAARAAPALQP	DUX4L5	206	P0CJ88
SAQFTVVGPANPILA	BTN2A2	31	Q8WVV5
ILSAAPIQVGQPALF	BICRA	541	Q9NZM4
TLATVSAGAAAPQPQ	C4orf54	46	D6RIA3
PGLPGSRNLVTAFSN	COL15A1	1126	P39059
LNLTIPQAPNGSFLT	SLC22A14	116	Q9Y267
LATSALPAGNVFNAP	SCAF8	746	Q9UPN6
ASGASVNTPFINLPA	SBSN	566	Q6UWP8
LSAPSISFRINGQPV	RYR2	761	Q92736
GIPLSPASLNQILFA	DSEL	1146	Q8IZU8
PLSGQFLQPAASAAA	FOXD3	451	Q9UJU5
FPSGLLNAQAPAALA	FEZF2	191	Q8TBJ5
SNQLLGVPPGLFANA	NRROS	411	Q86YC3
GFPNEPAAVIALNTI	MACROD2	191	A1Z1Q3
LVAAPGSTQAQAAPF	IGF2R	31	P11717
AAPAVSLVNNGPAAL	TAF4	211	O00268
VQAAPPAAQTLAASG	TAF4	351	O00268
APVAVAGAPITLNTA	SP4	511	Q02446
GADAPAVTPFQSLQL	PRLHR	41	P49683
ALNQFPAAPIPTLSG	SYNRG	376	Q9UMZ2
GPSSPVALLGQVQDF	PLEKHG3	1166	A1L390
AQAPQVLSPTFGAQD	SCRN2	326	Q96FV2
SLANLPPSGLANAVA	HAVCR2	241	Q8TDQ0
PGSAPLQRNFSINSV	PRC1	561	O43663
NGSLVPASTSPVFLN	SIX4	351	Q9UIU6
TALQLPSATAPGNFL	SIX5	526	Q8N196
PSATAPGNFLLANPV	SIX5	531	Q8N196
PFLGSQSATPVLQAQ	SIK1B	541	A0A0B4J2F2
PFLGSQSATPVLQAQ	SIK1	541	P57059
NFNALSVPPAGAKQT	SCYL2	816	Q6P3W7
VLCPNSNNSLLAFPG	WDR45B	146	Q5MNZ6
NLAVALPQEPASAGL	SSTR5	271	P35346
PAIVAAVQGNLLPSA	SMARCC2	1171	Q8TAQ2
PLLSFQATDPVNGTV	SPAG17	1416	Q6Q759
GSQLLVNFGLSPAAP	SLC39A5	161	Q6ZMH5
SSVPVQPEQLASAGF	BIRC2	281	Q13490
AFVQPLLSAGQAPLL	CIC	1051	Q96RK0
FQSIPAQSGQASPLL	CLTCL1	401	P53675
FTQILAPQAVGSGIP	CLCN2	151	P51788
ARNVPGFLPTNDLSQ	CNOT1	1576	A5YKK6
ALVVNFSQPVAGRPS	NLN	471	Q9BYT8
RVQGAAFLAQSPETP	PRSS53	271	Q2L4Q9
AAGAQATPQVFDLLP	THBS4	21	P35443
LSQTIPFTPVQLFAG	TRPM6	1721	Q9BX84
TGVSLALFPVAQAPT	SLC16A13	291	Q7RTY0
SCQFPVLPQAALAAG	ROM1	56	Q03395
ASPTLFNAGTNRPQL	RRM1	201	P23921
GLLVAPVSQQSPFLG	SLC27A3	486	Q5K4L6
IPAIDPALFNTISQG	VTA1	246	Q9NP79
FVSGNNRTAAPITLP	RYR3	421	Q15413
GNIFLPNSITPEALS	TBX22	451	Q9Y458
QGPDVAPSFLNSVLN	RNF123	1021	Q5XPI4
AFPDSPGLNRTVVNI	SPR	141	P35270
AQAPAPQAAEFLSPV	SLC19A1	526	P41440
QFPRLGAPSTGLSQA	SAP130	31	Q9H0E3
GATIVANPISNPFSA	SAP130	626	Q9H0E3
IAFVPPQSDLSNSLG	ZNF292	1071	O60281
NETNFVISPAGVSLP	SERPINE3	46	A8MV23
GPAPQLPLAVATDNF	TESK1	481	Q15569
NPVSLTPFQFGVSNL	NUP153	991	P49790
PLASPVASQVNGALA	PLCB2	846	Q00722
AAGAILRANSSQVPP	RBPJ	456	Q06330
NQIASLPSGVFQPLA	VASN	86	Q6EMK4
FPAIQGASLPALTTQ	ZSWIM8	1621	A7E2V4
RAASPVAFQGAQPIA	ZCCHC18	241	P0CG32
ELLQFSPSARPSAGQ	TSSK6	246	Q9BXA6
FQANLPGVLPALTGV	TTC12	421	Q9H892
PAITNGPRITNAFSI	ZBTB38	156	Q8NAP3
APAASLQFQGLPEGI	VSIG10L	521	Q86VR7
TGVAFNPSAPQLATA	WDR27	801	A2RRH5
PSFLASQQLLSQAGP	WNK2	1396	Q9Y3S1
ALQPQQASPGASSFL	nan	46	Q6AWC8
PLSGPLIQAQAEAFA	TIGD5	141	Q53EQ6
SNIGLNDPSIIFAQP	TUT4	1521	Q5TAX3
AVPLAGEAAAPAQLQ	XIRP1	1001	Q702N8
PAAPSAAQANAILAP	ZNF318	1461	Q5VUA4
NGLQSSLNPAAFVPI	TTLL5	1256	Q6EMB2
ATSPAVALSANGPAQ	YEATS2	956	Q9ULM3
SLGPAAPNSQTFLLV	ZNF628	701	Q5EBL2
LSVAGILNAAQPPAV	TMPPE	176	Q6ZT21
AFVSQAARAAPALQP	DUX4L2	206	P0CJ85
SSSFNPLNGTLLPVA	KLHL1	86	Q9NR64
LALSQPPTGQGAQAF	EXD3	431	Q8N9H8
PPTGQGAQAFSRLVA	EXD3	436	Q8N9H8