Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A3 COL4A4 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL28A1 COL27A1 COL1A2

5.84e-15468810GO:0030020
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL4A3 COL4A4 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 HMCN2 COL19A1 COL28A1 COL27A1 COL1A2

3.75e-111888812GO:0005201
GeneOntologyMolecularFunctioninsulin receptor activity

IGF1R INSRR

5.74e-053882GO:0005009
GeneOntologyMolecularFunctionstructural molecule activity

COL4A3 COL4A4 COL4A6 HSPG2 COL24A1 COL9A2 IGF1R COL13A1 HMCN2 COL19A1 COL28A1 COL27A1 COL1A2

1.38e-048918813GO:0005198
GeneOntologyMolecularFunctioncalcium- and calmodulin-responsive adenylate cyclase activity

ADCY1 ADCY8

1.90e-045882GO:0008294
GeneOntologyMolecularFunctionactin binding

MICAL1 MSRB1 SPATA31A1 SPATA31A3 MAPT SPATA31A7 SPATA31A6 SPATA31A5 ADCY8

2.60e-04479889GO:0003779
GeneOntologyBiologicalProcessextracellular matrix organization

COL4A3 COL4A4 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 COL19A1 COL28A1 COL27A1 COL1A2

5.32e-073778711GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

COL4A3 COL4A4 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 COL19A1 COL28A1 COL27A1 COL1A2

5.46e-073788711GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

COL4A3 COL4A4 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 COL19A1 COL28A1 COL27A1 COL1A2

5.60e-073798711GO:0045229
GeneOntologyBiologicalProcessneuron development

CERS2 ONECUT2 SPRY3 HSPG2 KIFBP IGF1R HMCN2 EFNB3 FOXO6 DKK1 MAPT ASCL1 GPRIN1 GRM7 FZD2 ADCY1 PREX1 LRP8

3.24e-0514638718GO:0048666
GeneOntologyBiologicalProcesspositive regulation of CREB transcription factor activity

ADCY1 ADCY8 LRP8

5.65e-0518873GO:0032793
GeneOntologyBiologicalProcessanimal organ morphogenesis

ONECUT2 HSPG2 IGF1R COL13A1 DKK1 UNCX SOBP COL27A1 PKD1 SP6 IRX3 ZFPM1 IRX1 FZD2 RYR2 COL1A2

7.17e-0512698716GO:0009887
GeneOntologyBiologicalProcesscognition

FOXO6 DKK1 ATXN1 MAPT SOBP NSUN5P2 GRM7 ADCY1 ADCY8

7.36e-05423879GO:0050890
GeneOntologyBiologicalProcessspecification of loop of Henle identity

IRX3 IRX1

1.05e-044872GO:0072086
GeneOntologyBiologicalProcessmemory

FOXO6 ATXN1 MAPT GRM7 ADCY1 ADCY8

1.25e-04183876GO:0007613
GeneOntologyBiologicalProcessspecification of nephron tubule identity

IRX3 IRX1

1.74e-045872GO:0072081
GeneOntologyBiologicalProcessproximal/distal pattern formation involved in nephron development

IRX3 IRX1

1.74e-045872GO:0072047
GeneOntologyCellularComponentcollagen trimer

COL4A3 COL4A4 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL20A1 COL28A1 COL27A1 MARCO COL1A2

2.99e-15889012GO:0005581
GeneOntologyCellularComponentcomplex of collagen trimers

COL4A3 COL4A4 COL4A6 COL28A1 COL27A1 COL1A2

2.77e-1021906GO:0098644
GeneOntologyCellularComponentcollagen-containing extracellular matrix

COL4A3 COL4A4 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 HMCN2 COL19A1 COL20A1 COL28A1 COL27A1 MARCO COL1A2

5.91e-085309014GO:0062023
GeneOntologyCellularComponentendoplasmic reticulum lumen

COL4A3 COL4A4 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL20A1 COL28A1 COL27A1 COL1A2

1.87e-073329011GO:0005788
GeneOntologyCellularComponentextracellular matrix

COL4A3 COL4A4 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 HMCN2 COL19A1 COL20A1 COL28A1 COL27A1 MARCO COL1A2

7.83e-076569014GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

COL4A3 COL4A4 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 HMCN2 COL19A1 COL20A1 COL28A1 COL27A1 MARCO COL1A2

8.12e-076589014GO:0030312
GeneOntologyCellularComponentcollagen type IV trimer

COL4A3 COL4A4 COL4A6

1.53e-066903GO:0005587
GeneOntologyCellularComponentbasement membrane collagen trimer

COL4A3 COL4A4 COL4A6

4.25e-068903GO:0098651
GeneOntologyCellularComponentnetwork-forming collagen trimer

COL4A3 COL4A4 COL4A6

4.25e-068903GO:0098642
GeneOntologyCellularComponentcollagen network

COL4A3 COL4A4 COL4A6

4.25e-068903GO:0098645
GeneOntologyCellularComponentbasement membrane

COL4A3 COL4A4 COL4A6 HSPG2 HMCN2 COL28A1

1.46e-05122906GO:0005604
GeneOntologyCellularComponentfibrillar collagen trimer

COL28A1 COL27A1 COL1A2

1.65e-0512903GO:0005583
GeneOntologyCellularComponentbanded collagen fibril

COL28A1 COL27A1 COL1A2

1.65e-0512903GO:0098643
GeneOntologyCellularComponentinsulin receptor complex

IGF1R INSRR

1.09e-044902GO:0005899
GeneOntologyCellularComponenthippocampal mossy fiber to CA3 synapse

EFNB3 GRIN3B ADCY1 ADCY8

2.00e-0467904GO:0098686
GeneOntologyCellularComponentsupramolecular polymer

COL4A3 COL4A4 COL4A6 MICAL1 MAPT COL28A1 CARMIL1 COL27A1 IFFO2 KLC3 RYR2 AHNAK2 DNAH1 COL1A2

5.29e-0411879014GO:0099081
GeneOntologyCellularComponentchromatin

ONECUT2 SP8 CEBPA FOXO6 BRD2 UNCX EP400 TFAP2E ASCL1 SP6 NPAS3 EHMT1 IRX3 ZFPM1 IRX1 GATAD2B

5.33e-0414809016GO:0000785
GeneOntologyCellularComponentaxon

MICAL1 IGF1R HMCN2 MAPT INSRR IRX3 GPRIN1 GRM7 PREX1 ADCY8 LRP8

1.53e-038919011GO:0030424
GeneOntologyCellularComponentacrosomal vesicle

SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

1.98e-03206905GO:0001669
GeneOntologyCellularComponentasymmetric synapse

EFNB3 MAPT GRIN3B GRM7 ADCY1 ADCY8 LRP8

4.52e-03477907GO:0032279
GeneOntologyCellularComponentpostsynaptic density membrane

EFNB3 GRIN3B ADCY1 LRP8

4.74e-03157904GO:0098839
MousePhenoperinatal lethality, complete penetrance

SP8 KIFBP IGF1R MAN1A2 CEBPA KMT2B DKK1 UNCX ASCL1 COL27A1 PKD1 IRX1 GATAD2B ZNF503 COL1A2

6.41e-067127715MP:0011089
MousePhenoabnormal telencephalon morphology

CERS2 HSPG2 MICAL1 KIFBP DKK1 TFAP2E MAPT ASCL1 PKD1 NPAS3 EHMT1 NSUN5P2 ADCY1 GATAD2B ZNF503 LRP8

7.02e-068127716MP:0000787
MousePhenoperinatal lethality

SP8 HSPG2 KIFBP IGF1R MAN1A2 CEBPA KMT2B BRD2 DKK1 UNCX ASCL1 COL27A1 PKD1 ZFPM1 IRX1 FZD2 GATAD2B ZNF503 COL1A2

8.30e-0611307719MP:0002081
MousePhenoabnormal forebrain morphology

CERS2 HSPG2 MICAL1 KIFBP BRD2 DKK1 TFAP2E MAPT ASCL1 PKD1 NPAS3 EHMT1 NSUN5P2 ADCY1 GATAD2B ZNF503 LRP8

5.79e-0510727717MP:0000783
MousePhenochondrodystrophy

HSPG2 COL27A1 PKD1

1.24e-0418773MP:0002657
MousePhenoreduced long-term potentiation

EFNB3 ATXN1 MAPT NSUN5P2 LRP8 RAVER1

1.25e-04141776MP:0001473
MousePhenoabnormal nervous system development

SP8 HSPG2 KIFBP IGF1R EFNB3 KMT2B BRD2 DKK1 EP400 TFAP2E MAPT ASCL1 PKD1 NPAS3 EHMT1 SOWAHB GATAD2B LRP8

1.26e-0412577718MP:0003861
MousePhenorespiratory distress

KIFBP MAN1A2 CEBPA ASCL1 PKD1 NPAS3 IRX1

1.29e-04204777MP:0001954
MousePhenoabnormal synaptic transmission

HSPG2 COL9A2 COL13A1 EFNB3 ATXN1 MAPT STRBP EHMT1 NSUN5P2 GRM7 ADCY1 PREX1 ADCY8 RYR2 LRP8 RAVER1

1.98e-0410707716MP:0003635
MousePhenoabnormal synaptic physiology

HSPG2 COL9A2 COL13A1 EFNB3 ATXN1 MAPT STRBP EHMT1 NSUN5P2 GRM7 ADCY1 PREX1 ADCY8 RYR2 LRP8 RAVER1

2.11e-0410767716MP:0021009
MousePhenoabnormal respiratory system development

MAN1A2 CEBPA DKK1 ASCL1 NPAS3 IRX1

2.48e-04160776MP:0003115
MousePhenoabnormal liver lobule morphology

HSPG2 KIFBP CEBPA KMT2B FOXO6 BRD2 PKD1

2.62e-04229777MP:0008987
MousePhenorespiratory failure

HSPG2 IGF1R CEBPA UNCX COL27A1 IRX1

2.93e-04165776MP:0001953
MousePhenoabnormal ductus venosus topology

KIFBP BRD2

2.96e-045772MP:0013874
MousePhenoabnormal synaptic depression

EFNB3 MAPT PREX1 ADCY8 RAVER1

3.05e-04107775MP:0002915
MousePhenoabnormal temporal memory

FOXO6 MAPT EHMT1 GRM7 PREX1 GATAD2B LRP8

3.40e-04239777MP:0001468
MousePhenodecreased respiration

HSPG2 IGF1R CEBPA UNCX COL27A1 IRX1

3.44e-04170776MP:0014274
MousePhenoabnormal liver parenchyma morphology

HSPG2 KIFBP CEBPA KMT2B FOXO6 BRD2 PKD1

3.76e-04243777MP:0008986
MousePhenoabnormal respiration

HSPG2 KIFBP IGF1R MAN1A2 CEBPA UNCX ASCL1 COL27A1 PKD1 NPAS3 IRX1

4.10e-045987711MP:0001943
MousePhenolethality during fetal growth through weaning, complete penetrance

SP8 KIFBP IGF1R MAN1A2 CEBPA KMT2B DKK1 UNCX SLC19A1 ASCL1 COL27A1 PKD1 IRX1 GATAD2B RYR2 ZNF503 COL1A2

4.44e-0412697717MP:0011111
DomainCollagen

COL4A3 COL4A4 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL20A1 COL28A1 COL27A1 MARCO COL1A2

4.11e-15858612IPR008160
DomainCollagen

COL4A3 COL4A4 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL20A1 COL28A1 COL27A1 MARCO COL1A2

4.11e-15858612PF01391
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

2.02e-0712864PF15371
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

2.02e-0712864IPR027970
DomainC4

COL4A3 COL4A4 COL4A6

1.87e-066863SM00111
Domain-

COL4A3 COL4A4 COL4A6

1.87e-0668632.170.240.10
DomainCollagen_VI_NC

COL4A3 COL4A4 COL4A6

1.87e-066863IPR001442
DomainC4

COL4A3 COL4A4 COL4A6

1.87e-066863PF01413
DomainNC1_IV

COL4A3 COL4A4 COL4A6

1.87e-066863PS51403
DomainTSPN

COL24A1 COL19A1 COL20A1 COL27A1

3.47e-0623864SM00210
DomainLaminin_G

HSPG2 COL24A1 COL19A1 COL20A1 COL27A1

6.96e-0658865IPR001791
DomainFib_collagen_C

COL24A1 COL27A1 COL1A2

1.51e-0511863IPR000885
DomainCOLFI

COL24A1 COL27A1 COL1A2

1.51e-0511863PF01410
DomainNC1_FIB

COL24A1 COL27A1 COL1A2

1.51e-0511863PS51461
DomainFib_collagen_C

COL24A1 COL27A1 COL1A2

1.51e-0511863PD002078
DomainCOLFI

COL24A1 COL27A1 COL1A2

1.51e-0511863SM00038
DomainTyr_kinase_insulin-like_rcpt

IGF1R INSRR

6.27e-053862IPR016246
DomainIRO

IRX3 IRX1

3.11e-046862SM00548
DomainIroquois_homeo

IRX3 IRX1

3.11e-046862IPR003893
DomainFurin-like

IGF1R INSRR

4.34e-047862PF00757
DomainRcpt_L-dom

IGF1R INSRR

4.34e-047862IPR000494
DomainFurin-like_Cys-rich_dom

IGF1R INSRR

4.34e-047862IPR006211
DomainRecep_L_domain

IGF1R INSRR

4.34e-047862PF01030
Domain-

IGF1R INSRR

4.34e-0478623.80.20.20
DomainConA-like_dom

HSPG2 COL24A1 COL19A1 COL20A1 COL27A1 RYR2

5.23e-04219866IPR013320
DomainAC_N

ADCY1 ADCY8

5.76e-048862IPR032628
DomainAdcy

ADCY1 ADCY8

5.76e-048862IPR030672
DomainAC_N

ADCY1 ADCY8

5.76e-048862PF16214
DomainLAM_G_DOMAIN

HSPG2 COL24A1 COL27A1

7.08e-0438863PS50025
DomainGrowth_fac_rcpt_

HSPG2 IGF1R HMCN2 INSRR LRP8

7.70e-04156865IPR009030
DomainSp1_fam

SP8 SP6

9.21e-0410862IPR030450
DomainTyr_kinase_rcpt_2_CS

IGF1R INSRR

1.12e-0311862IPR002011
DomainRECEPTOR_TYR_KIN_II

IGF1R INSRR

1.34e-0312862PS00239
DomainLDLRA_1

HSPG2 PKD1 LRP8

1.40e-0348863PS01209
DomainLDLRA_2

HSPG2 PKD1 LRP8

1.49e-0349863PS50068
DomainCTDL_fold

COL4A3 COL4A4 COL4A6 PKD1

1.51e-03107864IPR016187
DomainHomeobox_KN

IRX3 IRX1

2.72e-0317862PF05920
DomainA/G_cyclase_CS

ADCY1 ADCY8

2.72e-0317862IPR018297
DomainHomeobox_KN_domain

IRX3 IRX1

2.72e-0317862IPR008422
DomainFurin_repeat

IGF1R INSRR

3.06e-0318862IPR006212
DomainNucleotide_cyclase

ADCY1 ADCY8

3.06e-0318862IPR029787
DomainFU

IGF1R INSRR

3.06e-0318862SM00261
Domain-

ADCY1 ADCY8

3.06e-03188623.30.70.1230
DomainGUANYLATE_CYCLASE_1

ADCY1 ADCY8

3.41e-0319862PS00452
DomainGuanylate_cyc

ADCY1 ADCY8

3.41e-0319862PF00211
DomainGUANYLATE_CYCLASE_2

ADCY1 ADCY8

3.41e-0319862PS50125
DomainA/G_cyclase

ADCY1 ADCY8

3.41e-0319862IPR001054
DomainCYCc

ADCY1 ADCY8

3.41e-0319862SM00044
DomainHomeodomain-like

CERS2 ONECUT2 UNCX EP400 IRX3 IRX1

4.31e-03332866IPR009057
DomainHomeobox

CERS2 ONECUT2 UNCX IRX3 IRX1

4.52e-03234865PF00046
DomainHOMEOBOX_1

CERS2 ONECUT2 UNCX IRX3 IRX1

4.69e-03236865PS00027
DomainHOX

CERS2 ONECUT2 UNCX IRX3 IRX1

4.77e-03237865SM00389
DomainHOMEOBOX_2

CERS2 ONECUT2 UNCX IRX3 IRX1

4.94e-03239865PS50071
DomainHomeobox_dom

CERS2 ONECUT2 UNCX IRX3 IRX1

4.94e-03239865IPR001356
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A3 COL4A4 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL20A1 COL28A1 COL27A1 COL1A2

8.01e-17446711M27812
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A3 COL4A4 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL20A1 COL28A1 COL27A1 COL1A2

1.23e-14676711M26999
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A3 COL4A4 COL4A6 COL9A2 COL13A1 COL19A1 COL20A1 COL28A1 COL1A2

2.20e-1341679MM15538
PathwayREACTOME_COLLAGEN_FORMATION

COL4A3 COL4A4 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL20A1 COL28A1 COL27A1 COL1A2

3.67e-13906711M631
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A3 COL4A4 COL4A6 COL9A2 COL13A1 COL19A1 COL20A1 COL28A1 COL1A2

1.01e-1161679MM14637
PathwayREACTOME_COLLAGEN_FORMATION

COL4A3 COL4A4 COL4A6 COL9A2 COL13A1 COL19A1 COL20A1 COL28A1 COL1A2

7.86e-1176679MM14573
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A3 COL4A4 COL4A6 COL24A1 COL9A2 COL27A1 COL1A2

1.41e-0861677M27103
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A3 COL4A4 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 COL19A1 COL20A1 COL28A1 COL27A1 COL1A2

1.46e-083006712M610
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A3 COL4A4 COL4A6 COL9A2 COL13A1 COL19A1 COL1A2

1.99e-0864677M26953
PathwayPID_AVB3_INTEGRIN_PATHWAY

COL4A3 COL4A4 COL4A6 COL9A2 IGF1R COL13A1 COL1A2

5.56e-0874677M160
PathwayPID_SYNDECAN_1_PATHWAY

COL4A3 COL4A4 COL4A6 COL9A2 COL13A1 COL1A2

7.40e-0846676M198
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A3 COL4A4 COL4A6 HSPG2 COL9A2 COL13A1 COL1A2

1.46e-0785677M16441
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A3 COL4A4 COL4A6 COL13A1 COL19A1 COL1A2

1.77e-0753676MM14566
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A3 COL4A4 COL4A6 HSPG2 COL9A2 COL13A1 COL19A1 COL1A2

3.08e-07140678M587
PathwayREACTOME_ANCHORING_FIBRIL_FORMATION

COL4A3 COL4A4 COL4A6 COL1A2

6.12e-0715674M27161
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A3 COL4A4 COL4A6 COL1A2

1.36e-0618674M27164
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A3 COL4A4 COL4A6 COL1A2

1.36e-0618674MM14882
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A3 COL4A4 COL4A6 COL9A2 COL13A1 COL1A2

1.54e-0676676MM14867
PathwayREACTOME_ECM_PROTEOGLYCANS

COL4A3 COL4A4 COL4A6 HSPG2 COL9A2 COL1A2

1.54e-0676676M27219
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A3 COL4A4 COL4A6 COL9A2 COL13A1 COL19A1 COL20A1 COL28A1 COL1A2

3.39e-06258679MM14572
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A3 COL4A4 COL4A6 COL9A2 COL1A2

3.74e-0650675MM14796
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A3 COL4A4 COL4A6 HSPG2 COL1A2

8.55e-0659675M27218
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A3 COL4A4 COL4A6 HSPG2

1.16e-0530674M27216
PathwayBIOCARTA_NPP1_PATHWAY

COL4A3 COL4A4 COL4A6

1.20e-0510673M22040
PathwayBIOCARTA_NPP1_PATHWAY

COL4A3 COL4A4 COL4A6

1.20e-0510673MM1560
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A3 COL4A4 COL4A6 COL1A2

1.52e-0532674MM14924
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A3 COL4A4 COL4A6 COL13A1 COL19A1 COL1A2

1.64e-05114676MM14571
PathwayBIOCARTA_VITCB_PATHWAY

COL4A3 COL4A4 COL4A6

1.65e-0511673M15422
PathwayBIOCARTA_VITCB_PATHWAY

COL4A3 COL4A4 COL4A6

2.19e-0512673MM1526
PathwayBIOCARTA_ACE2_PATHWAY

COL4A3 COL4A4 COL4A6

2.84e-0513673MM1347
PathwayBIOCARTA_ACE2_PATHWAY

COL4A3 COL4A4 COL4A6

2.84e-0513673M12950
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A3 COL4A4 COL4A6

3.60e-0514673MM1458
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A3 COL4A4 COL4A6

3.60e-0514673M6487
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A3 COL4A4 COL4A6

4.48e-0515673MM14922
PathwayPID_INTEGRIN3_PATHWAY

COL4A3 COL4A4 COL4A6 COL1A2

5.00e-0543674M53
PathwayBIOCARTA_AMI_PATHWAY

COL4A3 COL4A4 COL4A6

1.10e-0420673M15394
PathwayREACTOME_NCAM1_INTERACTIONS

COL4A3 COL4A4 COL9A2

1.10e-0420673MM15061
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A3 COL4A4 COL4A6

1.70e-0423673M15997
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A3 COL4A4 COL4A6

1.70e-0423673MM1427
PathwayPID_INTEGRIN1_PATHWAY

COL4A3 COL4A4 COL4A6 COL1A2

2.69e-0466674M18
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

COL24A1 COL27A1 COL1A2

3.80e-0430673M27772
PathwayKEGG_ECM_RECEPTOR_INTERACTION

COL4A4 COL4A6 HSPG2 COL1A2

6.76e-0484674M7098
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

COL4A3 COL4A4 COL9A2

7.69e-0438673MM14969
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

COL24A1 COL27A1 COL1A2

9.61e-0441673M27778
PathwayREACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY

ADCY1 ADCY8

9.77e-0410672M19522
PathwayREACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY

ADCY1 ADCY8

9.77e-0410672MM14668
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

COL4A3 COL4A4 COL4A6 PKD1 FZD2

9.97e-04161675M39770
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

MAPT GRIN3B ADCY1 ADCY8

1.03e-0394674M2843
PathwayREACTOME_NCAM1_INTERACTIONS

COL4A3 COL4A4 COL9A2

1.03e-0342673M7169
PathwayREACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION

MICAL1 CARMIL1 ZFPM1 KLC3 HMG20B

1.27e-03170675M941
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_ADENYLATE_CYCLASE

ADCY1 ADCY8

1.42e-0312672M27363
PathwayREACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY

ADCY1 ADCY8

1.95e-0314672MM14669
PathwayREACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY

ADCY1 ADCY8

1.95e-0314672M750
PathwayREACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION

CARMIL1 ZFPM1 KLC3 HMG20B

2.24e-03116674MM15715
PathwayKEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY

ADCY1 ADCY8

2.25e-0315672M47794
PathwayPID_LPA4_PATHWAY

ADCY1 ADCY8

2.25e-0315672M56
PathwayKEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY

ADCY1 ADCY8

2.25e-0315672M47504
PathwayREACTOME_SIGNALING_BY_PDGF

COL4A3 COL4A4 COL9A2

2.50e-0357673MM14713
PathwayWP_NEUROGENESIS_REGULATION_IN_THE_OLFACTORY_EPITHELIUM

MAPT ASCL1 LRP8

2.50e-0357673M48326
PathwayKEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY

ADCY1 ADCY8

2.56e-0316672M47645
PathwayKEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY

ADCY1 ADCY8

2.56e-0316672M47650
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB

ADCY1 ADCY8

2.56e-0316672MM14492
PathwayWP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE

ADCY1 ADCY8

2.56e-0316672M39849
PathwayREACTOME_SIGNALING_BY_PDGF

COL4A3 COL4A4 COL9A2

2.63e-0358673M2049
PathwayWP_CANCER_PATHWAYS

COL4A3 COL4A4 COL4A6 IGF1R CEBPA FZD2 ADCY1 ADCY8

2.68e-03507678M48302
PathwayREACTOME_PKA_ACTIVATION_IN_GLUCAGON_SIGNALLING

ADCY1 ADCY8

2.89e-0317672M26995
PathwayKEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY

ADCY1 ADCY8

2.89e-0317672M47544
PathwayPID_MYC_REPRESS_PATHWAY

CEBPA DKK1 COL1A2

3.32e-0363673M254
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

COL4A3 COL4A4 COL9A2

3.32e-0363673M11187
PathwayPID_ENDOTHELIN_PATHWAY

ADCY1 ADCY8 COL1A2

3.32e-0363673M8
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

COL4A3 COL4A4 COL24A1 COL9A2 IGF1R ASCL1 COL27A1 COL1A2

3.59e-03532678M27870
PathwayREACTOME_SCAVENGING_BY_CLASS_A_RECEPTORS

MARCO COL1A2

3.61e-0319672M27221
PathwayBIOCARTA_LIS1_PATHWAY

LRP8 DNAH1

3.61e-0319672M22005
PathwayPID_LYSOPHOSPHOLIPID_PATHWAY

MAPT ADCY1 ADCY8

3.63e-0365673M15
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB

ADCY1 ADCY8

4.00e-0320672M759
Pubmed

The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.

SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

6.95e-13692520850414
Pubmed

Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.

SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

6.95e-13692525930072
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

COL4A3 COL4A4 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 COL19A1 COL28A1 COL1A2

1.07e-11153921025037231
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

COL4A3 COL4A4 COL4A6 HSPG2 COL24A1 COL9A2 HMCN2 COL28A1 COL27A1 COL1A2

4.06e-11175921028071719
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

COL4A4 COL4A6 HSPG2 COL24A1 COL13A1 HMCN2 COL28A1 COL27A1 COL1A2

6.75e-1016792922159717
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

4.74e-092492532212159
Pubmed

MMP-9 from TNF alpha-stimulated keratinocytes binds to cell membranes and type I collagen: a cause for extended matrix degradation in inflammation?

COL4A3 COL4A4 COL4A6 COL1A2

5.72e-0999249878537
Pubmed

Interaction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycans.

COL4A3 COL4A4 COL4A6 HSPG2

9.51e-09109249136074
Pubmed

Binding of mouse and human fibulin-2 to extracellular matrix ligands.

COL4A3 COL4A4 COL4A6 HSPG2

1.49e-08119247500359
Pubmed

Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.

COL4A3 COL4A4 COL4A6 HSPG2

2.23e-081292416024816
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HSPG2 MSRB1 IGF1R SCAP KMT2B BRD2 EP400 TSNARE1 PKD1 EHMT1 ZFPM1 ZNF865 PREX1 SOWAHB AHNAK2 ZNF503

3.17e-081105921635748872
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

COL4A3 COL4A6 HSPG2 COL24A1 COL13A1 COL28A1 COL1A2

7.56e-0813592728675934
Pubmed

Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

COL4A3 COL4A4 COL4A6 HSPG2

8.14e-081692415878328
Pubmed

Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development.

COL4A3 COL4A4 COL4A6 COL1A2

1.72e-071992415689378
Pubmed

Expression of two novel mouse Iroquois homeobox genes during neurogenesis.

ASCL1 IRX3 IRX1

1.78e-07592310704856
Pubmed

Extracellular matrix of the human optic nerve head.

COL4A3 COL4A4 COL4A6

3.56e-0769232426947
Pubmed

Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome.

COL4A3 COL4A4 COL4A6

3.56e-07692310534397
Pubmed

Developmental distribution of collagen IV isoforms and relevance to ocular diseases.

COL4A3 COL4A4 COL4A6

3.56e-07692319275937
Pubmed

Distribution of basement membrane proteins in normal and fibrotic human liver: collagen type IV, laminin, and fibronectin.

COL4A3 COL4A4 COL4A6

3.56e-0769236988303
Pubmed

Stimulation of extracellular matrix components in the normal brain by invading glioma cells.

COL4A3 COL4A4 COL4A6

3.56e-0769239506531
Pubmed

Angiogenesis and collagen type IV expression in different endothelial cell culture systems.

COL4A3 COL4A4 COL4A6

3.56e-07692323551189
Pubmed

Monoclonal antibody to human basement membrane collagen type IV.

COL4A3 COL4A4 COL4A6

3.56e-0769236811420
Pubmed

Immunolocalization of collagen types, laminin and fibronectin in the normal human pancreas.

COL4A3 COL4A4 COL4A6

3.56e-0769236389236
Pubmed

Collagen IV in the developing lens capsule.

COL4A3 COL4A4 COL4A6

3.56e-07692312225806
Pubmed

A tumor derived motility factor that stimulates cell migration on extracellular matrix.

COL4A3 COL4A4 COL4A6

3.56e-0769239673377
Pubmed

Localization of type IV collagen a 1 to a 6 chains in basement membrane during mouse molar germ development.

COL4A3 COL4A4 COL4A6

3.56e-07692311732842
Pubmed

Regulation of protease nexin-1 target protease specificity by collagen type IV.

COL4A3 COL4A4 COL4A6

6.22e-0779238006028
Pubmed

Corneal cell proteins and ocular surface pathology.

COL4A3 COL4A4 COL4A6

6.22e-07792310416788
Pubmed

Interstitial collagens I, III, and VI sequester and modulate the multifunctional cytokine oncostatin M.

COL4A3 COL4A4 COL4A6

6.22e-07792311711546
Pubmed

Purification, partial characterization of rat kidney hyaluronic acid binding protein and its localization on the cell surface.

COL4A3 COL4A4 COL4A6

6.22e-0779231724753
Pubmed

Short amino acid sequences derived from C1q receptor (C1q-R) show homology with the alpha chains of fibronectin and vitronectin receptors and collagen type IV.

COL4A3 COL4A6 COL1A2

9.94e-0789231377218
Pubmed

Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II.

COL4A3 COL4A4 COL4A6

9.94e-0789233997552
Pubmed

Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium.

COL4A3 COL4A4 COL4A6

9.94e-07892329422532
Pubmed

Mice develop normally without tenascin.

COL4A3 COL4A4 HSPG2

9.94e-0789231383086
Pubmed

Molecular properties of wild-type and mutant betaIG-H3 proteins.

COL4A3 COL4A4 COL1A2

9.94e-07892311867580
Pubmed

Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth.

COL4A3 COL4A4 COL4A6

9.94e-07892310382266
Pubmed

Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.

COL4A3 COL4A4 COL4A6

1.49e-06992312101409
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

COL4A3 COL4A6 COL9A2 COL13A1 COL19A1 PKD1 COL1A2

1.50e-0621092716537572
Pubmed

Distribution of fibronectin, type I collagen, type IV collagen, and laminin in the cardiac jelly of the mouse embryonic heart with retinoic acid-induced complete transposition of the great arteries.

COL4A3 COL4A4 COL1A2

2.12e-06109239415455
Pubmed

Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development.

COL4A3 COL4A4 COL4A6

2.91e-061192314998921
Pubmed

Basement membrane fragility underlies embryonic lethality in fukutin-null mice.

COL4A3 COL4A4 COL4A6

3.87e-061292315837576
Pubmed

Matrilin-2 interacts with itself and with other extracellular matrix proteins.

COL4A3 COL4A4 COL4A6

3.87e-061292312180907
Pubmed

Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.

COL4A3 COL4A4 HSPG2

5.03e-061392312682087
Pubmed

Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.

COL4A3 COL4A4 COL4A6

6.38e-061492312878203
Pubmed

Deficits in behavioral sensitization and dopaminergic responses to methamphetamine in adenylyl cyclase 1/8-deficient mice.

ADCY1 ADCY8

6.92e-06292226146906
Pubmed

Calmodulin-stimulated adenylyl cyclase gene deletion affects morphine responses.

ADCY1 ADCY8

6.92e-06292216914643
Pubmed

Calcium-stimulated adenylyl cyclases modulate ethanol-induced neurodegeneration in the neonatal brain.

ADCY1 ADCY8

6.92e-06292215745964
Pubmed

Two genes, COL4A3 and COL4A4 coding for the human alpha3(IV) and alpha4(IV) collagen chains are arranged head-to-head on chromosome 2q36.

COL4A3 COL4A4

6.92e-0629229537506
Pubmed

Identification of mutations in the alpha 3(IV) and alpha 4(IV) collagen genes in autosomal recessive Alport syndrome.

COL4A3 COL4A4

6.92e-0629227987396
Pubmed

Coexpression of insulin receptor-related receptor and insulin-like growth factor 1 receptor correlates with enhanced apoptosis and dedifferentiation in human neuroblastomas.

IGF1R INSRR

6.92e-06292214654552
Pubmed

The COL4A3 and COL4A4 Digenic Mutations in cis Result in Benign Familial Hematuria in a Large Chinese Family.

COL4A3 COL4A4

6.92e-06292229742505
Pubmed

Is there a dominant-negative effect in individuals with heterozygous disease-causing variants in COL4A3/COL4A4?

COL4A3 COL4A4

6.92e-06292238214412
Pubmed

Calcium-stimulated adenylyl cyclases are critical modulators of neuronal ethanol sensitivity.

ADCY1 ADCY8

6.92e-06292215843614
Pubmed

Distinct roles of adenylyl cyclases 1 and 8 in opiate dependence: behavioral, electrophysiological, and molecular studies.

ADCY1 ADCY8

6.92e-06292218222416
Pubmed

COL4A3/COL4A4 mutations and features in individuals with autosomal recessive Alport syndrome.

COL4A3 COL4A4

6.92e-06292224052634
Pubmed

Clinico-pathological correlations in 127 patients in 11 large pedigrees, segregating one of three heterozygous mutations in the COL4A3/ COL4A4 genes associated with familial haematuria and significant late progression to proteinuria and chronic kidney disease from focal segmental glomerulosclerosis.

COL4A3 COL4A4

6.92e-06292219357112
Pubmed

Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis.

COL4A3 COL4A4

6.92e-06292225229338
Pubmed

Postsynaptic burst reactivation of hippocampal neurons enables associative plasticity of temporally discontiguous inputs.

ADCY1 ADCY8

6.92e-06292236226826
Pubmed

Persistent familial hematuria in children and the locus for thin basement membrane nephropathy.

COL4A3 COL4A4

6.92e-06292216235097
Pubmed

Distinct regional and subcellular localization of adenylyl cyclases type 1 and 8 in mouse brain.

ADCY1 ADCY8

6.92e-06292217335981
Pubmed

Memory Retrieval Re-Activates Erk1/2 Signaling in the Same Set of CA1 Neurons Recruited During Conditioning.

ADCY1 ADCY8

6.92e-06292228366664
Pubmed

The type 8 adenylyl cyclase is critical for Ca2+ stimulation of cAMP accumulation in mouse parotid acini.

ADCY1 ADCY8

6.92e-06292210799557
Pubmed

Calcium-stimulated adenylyl cyclases required for long-term potentiation in the anterior cingulate cortex.

ADCY1 ADCY8

6.92e-06292215985698
Pubmed

Adenylyl cylases 1 and 8 mediate select striatal-dependent behaviors and sensitivity to ethanol stimulation in the adolescent period following acute neonatal ethanol exposure.

ADCY1 ADCY8

6.92e-06292224769171
Pubmed

Calcium activated adenylyl cyclase AC8 but not AC1 is required for prolonged behavioral anxiety.

ADCY1 ADCY8

6.92e-06292227234425
Pubmed

Presumed COL4A3/COL4A4 Missense/Synonymous Variants Induce Aberrant Splicing.

COL4A3 COL4A4

6.92e-06292235386907
Pubmed

COL4A3/COL4A4 mutations: from familial hematuria to autosomal-dominant or recessive Alport syndrome.

COL4A3 COL4A4

6.92e-06292212028435
Pubmed

Overexpression of the type 1 adenylyl cyclase in the forebrain leads to deficits of behavioral inhibition.

ADCY1 ADCY8

6.92e-06292225568126
Pubmed

COL4A3/COL4A4 mutations link familial hematuria and focal segmental glomerulosclerosis. glomerular epithelium destruction via basement membrane thinning?

COL4A3 COL4A4

6.92e-06292218661361
Pubmed

Ca2+-stimulated ADCY1 and ADCY8 regulate distinct aspects of synaptic and cognitive flexibility.

ADCY1 ADCY8

6.92e-06292237465213
Pubmed

Temporal and regional regulation of gene expression by calcium-stimulated adenylyl cyclase activity during fear memory.

ADCY1 ADCY8

6.92e-06292220976279
Pubmed

Type 8 adenylyl cyclase is targeted to excitatory synapses and required for mossy fiber long-term potentiation.

ADCY1 ADCY8

6.92e-06292214585998
Pubmed

Cyclic AMP-dependent positive feedback signaling pathways in the cortex contributes to visceral pain.

ADCY1 ADCY8

6.92e-06292231665810
Pubmed

Resveratrol inhibits collagen I synthesis by suppressing IGF-1R activation in intestinal fibroblasts.

IGF1R COL1A2

6.92e-06292224782617
Pubmed

Genetic evidence for adenylyl cyclase 1 as a target for preventing neuronal excitotoxicity mediated by N-methyl-D-aspartate receptors.

ADCY1 ADCY8

6.92e-06292217121841
Pubmed

Mutation analysis of COL4A3 and COL4A4 genes in a Chinese autosomal-dominant Alport syndrome family.

COL4A3 COL4A4

6.92e-06292228674241
Pubmed

Mical modulates Tau toxicity via cysteine oxidation in vivo.

MICAL1 MAPT

6.92e-06292235379354
Pubmed

Genetic elimination of behavioral sensitization in mice lacking calmodulin-stimulated adenylyl cyclases.

ADCY1 ADCY8

6.92e-06292212441059
Pubmed

Heterozygous COL4A3/COL4A4 mutations: the hidden part of the iceberg?

COL4A3 COL4A4

6.92e-06292235090027
Pubmed

Adenylyl cyclases 1 and 8 initiate a presynaptic homeostatic response to ethanol treatment.

ADCY1 ADCY8

6.92e-06292219479030
Pubmed

Calcium-stimulated adenylyl cyclase activity is critical for hippocampus-dependent long-term memory and late phase LTP.

ADCY1 ADCY8

6.92e-06292210482244
Pubmed

Enhanced presynaptic neurotransmitter release in the anterior cingulate cortex of mice with chronic pain.

ADCY1 ADCY8

6.92e-06292216943548
Pubmed

Nine novel COL4A3 and COL4A4 mutations and polymorphisms identified in inherited membrane diseases.

COL4A3 COL4A4

6.92e-06292217216251
Pubmed

Heterozygous Urinary Abnormality-Causing Variants of COL4A3 and COL4A4 Affect Severity of Autosomal Recessive Alport Syndrome.

COL4A3 COL4A4

6.92e-06292235369551
Pubmed

Collagen type IV-related nephropathies in Portugal: pathogenic COL4A3 and COL4A4 mutations and clinical characterization of 25 families.

COL4A3 COL4A4

6.92e-06292225307543
Pubmed

Genetic, Clinical, and Pathologic Backgrounds of Patients with Autosomal Dominant Alport Syndrome.

COL4A3 COL4A4

6.92e-06292227281700
Pubmed

[From Alport syndrome to benign familial hematuria: clinical and genetic aspect].

COL4A3 COL4A4

6.92e-06292216895672
Pubmed

Type-IV collagen related diseases.

COL4A3 COL4A4

6.92e-06292212768082
Pubmed

Overexpression of type I adenylyl cyclase in the forebrain impairs spatial memory in aged but not young mice.

ADCY1 ADCY8

6.92e-06292219726641
Pubmed

A role for calmodulin-stimulated adenylyl cyclases in cocaine sensitization.

ADCY1 ADCY8

6.92e-06292219244515
Pubmed

COL4A3/COL4A4 mutations producing focal segmental glomerulosclerosis and renal failure in thin basement membrane nephropathy.

COL4A3 COL4A4

6.92e-06292217942953
Pubmed

Polymorphisms in COL4A3 and COL4A4 genes associated with keratoconus.

COL4A3 COL4A4

6.92e-06292220029656
Pubmed

Whole exome sequencing reveals novel COL4A3 and COL4A4 mutations and resolves diagnosis in Chinese families with kidney disease.

COL4A3 COL4A4

6.92e-06292225381091
Pubmed

Collagen type IV (alpha3-alpha4) nephropathy: from isolated haematuria to renal failure.

COL4A3 COL4A4

6.92e-06292215280517
Pubmed

The genetics of thin basement membrane nephropathy.

COL4A3 COL4A4

6.92e-06292215880327
Pubmed

Spatiotemporal localization of the calcium-stimulated adenylate cyclases, AC1 and AC8, during mouse brain development.

ADCY1 ADCY8

6.92e-06292215844169
Pubmed

Distinct mechanisms of regulation by Ca2+/calmodulin of type 1 and 8 adenylyl cyclases support their different physiological roles.

ADCY1 ADCY8

6.92e-06292219029295
Pubmed

Polymorphism analysis of COL4A3 and COL4A4 genes in Greek patients with keratoconus.

COL4A3 COL4A4

6.92e-06292225083577
Pubmed

Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly.

COL4A3 COL4A4

6.92e-06292220847057
Pubmed

Circadian oscillation of hippocampal MAPK activity and cAmp: implications for memory persistence.

ADCY1 ADCY8

6.92e-06292219160506
CytobandEnsembl 112 genes in cytogenetic band chr9q12

SPATA31A7 SPATA31A5

1.10e-048922chr9q12
CytobandEnsembl 112 genes in cytogenetic band chr9q34

HMCN2 EHMT1 PNPLA7 PRRT1B QSOX2

5.12e-04325925chr9q34
CytobandEnsembl 112 genes in cytogenetic band chr2q36

COL4A3 COL4A4 SGPP2

6.83e-0485923chr2q36
Cytoband17q21.1

MAPT FZD2

7.37e-042092217q21.1
Cytoband9p13.1

SPATA31A1 SPATA31A3

1.07e-03249229p13.1
Cytoband9q34.3

EHMT1 PNPLA7 QSOX2

1.29e-031069239q34.3
Cytoband16p13.3

MSRB1 PRSS41 AMDHD2 PKD1

1.51e-0324492416p13.3
CytobandEnsembl 112 genes in cytogenetic band chr1p34

COL9A2 TRIT1 FOXO6 TFAP2E

2.96e-03294924chr1p34
GeneFamilyCollagens

COL4A3 COL4A4 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL20A1 COL28A1 COL27A1 COL1A2

9.21e-18466711490
GeneFamilyZinc fingers C2H2-type|Sp transcription factors

SP8 SP6

4.79e-049672755
GeneFamilyAdenylate cyclases|Deafness associated genes

ADCY1 ADCY8

5.97e-041067253
CoexpressionNABA_COLLAGENS

COL4A3 COL4A4 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL20A1 COL28A1 COL27A1 COL1A2

1.68e-18438811MM17060
CoexpressionNABA_COLLAGENS

COL4A3 COL4A4 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL20A1 COL28A1 COL27A1 COL1A2

2.24e-18448811M3005
CoexpressionNABA_CORE_MATRISOME

COL4A3 COL4A4 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 HMCN2 COL19A1 COL20A1 COL28A1 COL27A1 COL1A2

6.65e-122708813MM17057
CoexpressionNABA_CORE_MATRISOME

COL4A3 COL4A4 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 HMCN2 COL19A1 COL20A1 COL28A1 COL27A1 COL1A2

8.37e-122758813M5884
CoexpressionBENPORATH_PRC2_TARGETS

ONECUT2 COL4A6 COL24A1 COL9A2 DKK1 TFAP2E MAPT ASCL1 COL27A1 INSRR SGPP2 IRX3 GRM7 FZD2 ADCY8 ZNF503

4.72e-106508816M8448
CoexpressionBENPORATH_ES_WITH_H3K27ME3

ONECUT2 COL4A6 COL24A1 COL9A2 DKK1 TFAP2E MAPT ASCL1 COL27A1 INSRR SGPP2 IRX3 ZFPM1 IRX1 GRM7 FZD2 ADCY8 ZNF503

2.62e-0811158818M10371
CoexpressionBENPORATH_SUZ12_TARGETS

ONECUT2 COL4A6 COL24A1 COL9A2 DKK1 TFAP2E MAPT ASCL1 COL27A1 INSRR SGPP2 IRX3 IRX1 GRM7 FZD2 ADCY8 ZNF503

5.28e-0810358817M9898
CoexpressionBENPORATH_EED_TARGETS

ONECUT2 COL4A6 COL24A1 COL9A2 COL19A1 DKK1 TFAP2E MAPT ASCL1 COL27A1 INSRR SGPP2 IRX3 GRM7 FZD2 ADCY8 ZNF503

7.35e-0810598817M7617
CoexpressionNABA_BASEMENT_MEMBRANES

COL4A3 COL4A4 COL4A6 HSPG2

9.88e-0640884M5887
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

COL9A2 COL13A1 UNCX TFAP2E INSRR NPAS3 PODXL2 IRX1 GRIN3B

1.67e-05438889M1954
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

COL9A2 COL13A1 UNCX TFAP2E INSRR NPAS3 PODXL2 IRX1 GRIN3B

1.73e-05440889MM832
CoexpressionNABA_MATRISOME

COL4A3 COL4A4 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 HMCN2 COL19A1 COL20A1 COL28A1 COL27A1 COL1A2

3.09e-0510088813MM17056
CoexpressionNABA_MATRISOME

COL4A3 COL4A4 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 HMCN2 COL19A1 COL20A1 COL28A1 COL27A1 COL1A2

3.71e-0510268813M5889
CoexpressionGSE17721_LPS_VS_POLYIC_8H_BMDC_DN

MICAL1 TRIT1 MAN1A2 CARMIL1 IFFO2 LRP8

5.74e-05199886M3813
CoexpressionHEBERT_MATRISOME_TNBC_LUNG_METASTASIS

COL4A3 COL4A4 HSPG2

6.17e-0523883M48001
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K27ME3

SP8 COL13A1 UNCX SGPP2 GRM7 SOWAHB RYR2

1.64e-04345887M2009
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K27ME3

SP8 COL13A1 UNCX SGPP2 GRM7 SOWAHB RYR2

1.70e-04347887MM860
CoexpressionYAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_7

BRD2 ZFPM1 FZD2 LRP8

1.86e-0484884MM873
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 COL4A4 FOXO6 PERM1 IRX3 IRX1 KLC3

7.32e-0817392745808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 COL4A4 FOXO6 PERM1 IRX3 IRX1 KLC3

7.32e-081739277fa9dbcb258c3ab974490063951620e2def03db1
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A3 COL4A4 IGF1R COL13A1 MAPT PERM1 ZNF503

1.20e-071869272cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A3 COL4A4 IGF1R COL13A1 MAPT PERM1 ZNF503

1.20e-0718692790d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A3 COL4A4 HSPG2 COL24A1 SOBP FZD2 COL1A2

1.24e-07187927ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

ONECUT2 ATXN1 MAPT GRM7 ADCY1 RYR2 ZNF503

1.39e-071909276e92c78799f34b31d098854503c796edb0dc7f80
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

COL4A3 COL4A4 SOBP LIPH CARMIL1 NPAS3 COL1A2

1.44e-07191927d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellP07-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 COL4A4 LIPH IRX1 FZD2 DNAH1

7.85e-071539265501095bcf73080872ae01128f21399f9cfc5dd1
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

COL4A3 COL4A4 HSPG2 DKK1 FZD2 KLC3

1.02e-0616092658ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL24A1 MCM8 SOBP SLC19A1 ADCY8 RYR2

1.61e-061739263059325901b1e5e12a1a91183f14267288b2f600
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL24A1 MCM8 SOBP SLC19A1 ADCY8 RYR2

1.61e-0617392636c8338463ee4cc432f568728d55989360f9a68d
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

COL4A3 COL4A4 SOBP LIPH INSRR COL1A2

1.96e-06179926dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 HSPG2 LIPH IRX3 IRX1

2.37e-061859266da9a06e1514d5d5f47359a14637f02539846096
ToppCellControl-Epithelial_alveolar|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A4 COL4A6 CARMIL1 IRX3 IRX1

2.37e-061859263937e026add96a396122139daf8011cfbc60e75c
ToppCellP28-Epithelial-alveolar_epithelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 COL4A4 CEBPA LIPH IRX3 IRX1

2.37e-061859265bb513e569f3a197d55ae2ca683e202daebabeac
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 HSPG2 LIPH IRX3 IRX1

2.37e-061859264a188e2566a75d1b4f3c879a8c241c277c4b451c
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL4A3 COL4A4 HMCN2 LIPH CARMIL1 COL1A2

2.52e-061879264ea486991f66c29728d127171a07b81404ec0b78
ToppCellLPS-antiTNF-Epithelial_alveolar|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A4 COL4A6 SGPP2 IRX3 IRX1

2.52e-06187926201ff693e4756ee3e44762885b3a303a77eb535b
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL9A2 CEBPA BRD2 IFFO2 IRX3 KLC3

2.68e-06189926965e0e388251e7318f8b463816dc96ccb4658677
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A4 COL4A6 SGPP2 IRX3 IRX1

2.68e-061899265f883ef4cc0383142d538ae61f4fb40dfdb8ef18
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A3 COL4A4 COL13A1 MAPT PERM1 ZNF503

2.68e-06189926ce5b3d53c9a5457a5a02b221dee18334b5eaf8b7
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL4A3 COL4A4 SOBP CARMIL1 NPAS3 ADCY1

2.76e-0619092612992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

COL4A3 COL4A4 COL24A1 SOBP CARMIL1 COL1A2

2.94e-06192926356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

COL4A3 COL4A4 SOBP CARMIL1 NPAS3 COL1A2

3.03e-06193926dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

COL4A3 COL4A4 HMCN2 SOBP CARMIL1 COL1A2

3.21e-06195926a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

COL4A3 COL4A4 COL24A1 SOBP CARMIL1 COL1A2

3.21e-061959266a02ebbeb3199447ddce64d92d8809436e040eba
ToppCellwk_15-18-Epithelial-Distal_epithelial-type_II_pneumocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL4A3 COL4A4 HSPG2 CEBPA IRX3 IRX1

3.21e-061959260e3aac1b1a1fd483f5fb9a394eb90c0e1ce63542
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate|5w / Sample Type, Dataset, Time_group, and Cell type.

IGF1R EFNB3 MAPT SOBP NPAS3 GATAD2B

3.71e-06200926c92e4fc0442404481fcac623d691dae6215b852d
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-Kcnj8|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL4A3 COL4A4 HMCN2 COL28A1 IRX3

3.78e-061139250651fb7a7e1ea84b8365059e5ed85bf6c082da1a
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-Kcnj8-MURAL_Mural.Acta2Rgs5.Kcnj8-Abcc9_(Mural.Acta2Rgs5.Kcnj8-Abcc9)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL4A3 COL4A4 HMCN2 COL28A1 IRX3

3.78e-061139250e153efddd061d7510dfc3859cc8b1a7984fa70e
ToppCellSubstantia_nigra|World / BrainAtlas - Mouse McCarroll V32

UNCX IRX3 IRX1 MARCO ZNF503

4.12e-0611592518174b8d57d444fab1e9d2b13d22939c83c958e0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 HSPG2 UNCX IRX3

1.27e-051459258da10bc6611976e1ec85e09f04a2dc5bf6555c9e
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-NP-L6_NP_ALM_Trh|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL24A1 EFNB3 ACAA1 ASCL1 KLC3

1.45e-05149925fe9dff31a30dabd212d53d1295f9f13ff32cb217
ToppCellPND07-28-samps-Myeloid-Macrophage-macrophage-B|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MSRB1 CEBPA ACAA1 PNPLA7 MARCO

2.05e-05160925694bf1f1952bd8ab444819f533da24fa2b73f701
ToppCellPND07-28-samps-Myeloid-Macrophage|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MSRB1 CEBPA ACAA1 PNPLA7 MARCO

2.17e-051629257c73fe8388af370461e04097cf145cbc9847285b
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CEBPA AMDHD2 SGPP2 QSOX2 SOWAHB

2.59e-0516892508f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL4A6 HSPG2 COL13A1 FZD2 COL1A2

2.82e-051719252e43fb129ee9bdc3b31febc43c10f959bf0f4a7d
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL4A6 HSPG2 COL13A1 FZD2 COL1A2

2.82e-05171925e219a1aa59a96e4bc3e2eacf985679174a51de41
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MSRB1 CEBPA ACAA1 PREX1 MARCO

2.90e-05172925584af6537685cb459bf0fc298e6f46872016c116
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL4A3 COL4A4 COL28A1 SP6

2.92e-05859247c5ea38893372fdecf7cc3ccf46a37b4ec45f0b1
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL4A3 COL4A4 COL28A1 SP6

2.92e-05859245a2c02aeceeabd44a417b09ac8b2e2f185070b15
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL4A3 COL4A4 COL28A1 SP6

2.92e-05859240bfabb6761a84d6a04f9fa415106a33059d78099
ToppCellP07-Epithelial|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 COL4A4 CEBPA IRX3 IRX1

2.98e-051739258b10087a917b825809d35a2b2b349c73a2782472
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL4A6 HSPG2 COL13A1 FZD2 COL1A2

3.06e-051749252891ab2fd05eb4bbd239d1a2865f21ef7f2df39e
ToppCellP07-Epithelial-alveolar_epithelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 COL4A4 CEBPA IRX3 IRX1

3.06e-051749252739de68e0266054694f99807cfb1f07b6bbb371
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL4A6 HSPG2 COL13A1 FZD2 COL1A2

3.06e-05174925eade55f86ef1f7a5355ad65cec3aa6bfc5d3c62d
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 COL4A4 CARMIL1 IRX3 FZD2

3.14e-0517592596219e58dcb327fd27190be78193e7a0d611e62b
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 COL4A4 CARMIL1 IRX3 FZD2

3.14e-05175925cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

ONECUT2 NPAS3 PODXL2 GPRIN1 ADCY1

3.14e-051759254db1a3c284488b3f6de7568363f176d74e2a4587
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

ONECUT2 NPAS3 PODXL2 GPRIN1 ADCY1

3.14e-051759258d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CEBPA RASAL3 TFAP2E PNPLA7 PREX1

3.23e-05176925581d78811b2d99f38a2c7cc268aeb1cf932379c2
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL24A1 COL9A2 COL27A1 NPAS3 KLC3

3.23e-0517692577c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCellP03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 COL4A4 IGF1R IRX1 PRRT1B

3.23e-05176925f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MSRB1 CEBPA ACAA1 PNPLA7 MARCO

3.23e-05176925e74ad0db3b05897edcfabeb11008ede2b9eeb638
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL24A1 DKK1 GRM7 RYR2 COL1A2

3.32e-051779259ec7f1e64312d26d434b3312b58386715dbad644
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL24A1 DKK1 GRM7 RYR2 COL1A2

3.32e-05177925016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MSRB1 CEBPA ACAA1 PNPLA7 MARCO

3.32e-0517792571919b5c9bfa87fdd2cd44dfa057b66ea081be5d
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL4A6 HSPG2 COL13A1 FZD2 COL1A2

3.32e-05177925599cf7f5b774e197a1b43c98e4b9a8c1a618f38a
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

HMCN2 COL28A1 SP6 PERM1

3.35e-05889245fdfc72988dcbb7d2025866b2b00eab8f11f332f
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)|Hippocampus / BrainAtlas - Mouse McCarroll V32

HMCN2 COL28A1 SP6 PERM1

3.35e-0588924b9874366925fa1c08a74b14c3c6e127b9dffa23e
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LIPH SGPP2 IRX3 IRX1 RYR2

3.41e-0517892576e71fff99cf64302e2e3c0d66dd8ba0ff13624e
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LIPH SGPP2 IRX3 IRX1 RYR2

3.41e-0517892582f78ea1ea3ff3e2347cd8bc2f06e2a10e96f220
ToppCelldroplet-Lung-30m-Epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LIPH SGPP2 IRX3 IRX1 RYR2

3.41e-051789255442bc52b8e902da1383f44d97a9f95e471a8d4d
ToppCellwk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL9A2 COL27A1 TSNARE1 AHNAK2 DNAH1

3.41e-05178925a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LIPH SGPP2 IRX3 IRX1 RYR2

3.41e-05178925523b286ebe0359c7f1902f28cbd71f452626fc0d
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL4A6 COL13A1 INSRR FZD2 COL1A2

3.41e-05178925cda7695411655bd6d0ba69e5041ca7530a9dad3a
ToppCellP15-Epithelial|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 COL4A4 CEBPA IRX3 IRX1

3.50e-05179925869d3d203e2cb88636e2f0c4476c72571ae3b5ca
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A3 COL4A4 LIPH IRX3 IRX1

3.50e-0517992588dbec952507d84b85b08165eec80df99ed1e736
ToppCellfacs-Lung-EPCAM-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A3 COL4A4 LIPH IRX3 IRX1

3.50e-05179925daf8189a22786171e2b629261cf720736aa4ebdb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXO6 ACAA1 GPRIN1 ADCY8 DNAH1

3.50e-05179925479116ac65488c60104a053530830763ec1f95b2
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXO6 ACAA1 GPRIN1 ADCY8 DNAH1

3.50e-051799251dfc0cb8b369aef35c59f3d4c52603dc9f3728c1
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXO6 ACAA1 GPRIN1 ADCY8 DNAH1

3.50e-0517992569a1b3b05c921de6343ffe6ad998aa2b804312a7
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 COL4A4 HSPG2 DKK1 SLC19A1

3.50e-051799251603117b52623663458a977c94bf7f9f6c1114b8
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL24A1 COL13A1 HMCN2 EFNB3 COL1A2

3.60e-05180925f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCell10x3'2.3-week_14-16-Lymphocytic_NK-T_NK-ILC_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL4A3 COL4A4 COL9A2 GRM7 PREX1

3.60e-0518092527672ac6a02172a31851f18decb9acffa8f5a703
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A3 COL4A4 COL4A6 HSPG2 COL1A2

3.60e-0518092539ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL13A1 COL28A1 PODXL2 FZD2 COL1A2

3.69e-05181925ebf1ae963a2b22e1772752ed85a4fb0e546d377e
ToppCellP03-Epithelial-alveolar_epithelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 COL4A4 CEBPA IRX3 IRX1

3.69e-05181925c3dbf8850d3812fbb770798f4cf38908db8bb92b
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Mesenchymal-Mes-Pericyte|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A3 COL4A4 SPATA31A1 SLC19A1 COL1A2

3.69e-05181925634a4f4e5942473e60d08d0b0936407b04bc6b7c
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Mesenchymal-Mes-Pericyte-Peri_L1-6_MUSTN1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A3 COL4A4 SPATA31A1 SLC19A1 COL1A2

3.69e-05181925c2938cf1f5d4875be07a56a1f36c94f8eab37d99
ToppCellP15-Epithelial-alveolar_epithelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 COL4A4 CEBPA IRX3 IRX1

3.69e-051819257033be0ba90556f7e5f7c0d4a9f7644afcb22c9b
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A6 COL24A1 PNPLA7 RYR2 COL1A2

3.69e-05181925b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellP03-Epithelial|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 COL4A4 CEBPA IRX3 IRX1

3.69e-05181925de0466072f5b2ab8db3d9bab31e3205d1ff7cfb7
ToppCellControl-Epithelial_alveolar-AT_1-AT1-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A4 COL4A6 IRX3 IRX1

3.79e-05182925a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 COL4A4 HSPG2 IRX3 FZD2

3.79e-05182925573771130247e869e4e58f22d4a1cb31989635cf
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 COL4A4 HSPG2 IRX3 FZD2

3.79e-051829256cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A4 IRX3 IRX1 KLC3

3.89e-05183925274483009b309289e4cb84beedf6806430db6ff6
ToppCellMesenchymal_cells-Osteoblasts|Mesenchymal_cells / Lineage and Cell class

COL24A1 COL13A1 DKK1 PREX1 COL1A2

3.89e-05183925d6b52d52fe9a7a6c798947f05420d79fe12e4662
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ONECUT2 COL24A1 COL19A1 RYR2 DNAH1

3.99e-051849252cbed6462fea2622871bb7e49b0df3d984239281
ToppCellP28-Epithelial|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 COL4A4 CEBPA IRX3 IRX1

3.99e-0518492505811d13bd8a602095a3fcf5e55345edadc7b8bf
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A4 COL4A6 IRX3 IRX1

3.99e-051849257cc5796557379c3d1db078c1aeda40659c6e401c
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HMCN2 COL19A1 NPAS3 ADCY8 LRP8

3.99e-051849257f6c8912677764d438ab0555faca344d74c2f483
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ONECUT2 COL24A1 COL19A1 RYR2 DNAH1

3.99e-05184925ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ONECUT2 COL24A1 COL19A1 RYR2 DNAH1

3.99e-051849252b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CEBPA ACAA1 PNPLA7 PREX1 MARCO

3.99e-051849258e5fc2bdd3071e782aa8c56b8a39f8ea8f03f623
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

COL4A6 COL13A1 NPAS3 RYR2 COL1A2

4.10e-051859257dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCellPND01-03-samps-Epithelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

COL4A3 COL4A4 SGPP2 IRX3 IRX1

4.10e-051859252b854df79cfe2cb4d2f9c2938a066e0aa3649325
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A4 SGPP2 IRX3 IRX1

4.10e-051859250c247a3f394c42e2a6f67fee3d9cf33096fecd13
ToppCelldroplet-Lung-LUNG-1m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSRB1 CEBPA ACAA1 PNPLA7 MARCO

4.10e-0518592553a5218c1e6eb12daccde3d6e02f337e2586d74c
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPA BRD2 IFFO2 IRX3 KLC3

4.21e-05186925bd1185592aedebccd1007dbf2dd2f549fcdf9f42
DrugGK-101

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL27A1 COL1A2

6.01e-1136857CID000161853
DrugAC1LAKND

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 COL1A2

7.73e-1162858CID000470146
DrugPCR 4099

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 ADCY1 ADCY8 COL1A2

1.10e-101398510CID000002806
DrugBAPN

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 COL1A2

2.37e-1071858CID000001647
Drugmalotilate

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 ACAA1 COL27A1 COL1A2

2.37e-1071858CID000004006
DrugMadecassol

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL27A1 COL1A2

3.74e-1046857CID000108062
Drugd-indobufen

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL27A1 COL1A2

6.89e-1050857CID000044562
Drugridogrel

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL27A1 COL1A2

9.18e-1052857CID005362391
Drughalofuginone lactate

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 COL1A2

1.03e-0985858CID000062891
DrugNSC49633

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL27A1 COL1A2

1.05e-0953857CID000023340
Drug4-hydroxyproline

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 COL1A2

1.78e-0991858CID000000825
Drugticlopidine

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 COL1A2

4.81e-09103858CID000005472
Drughydroxylysine

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 COL1A2

7.54e-09109858CID000001029
DrugAC1L1C2F

COL4A3 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 COL27A1 COL1A2

8.11e-09110858CID000001711
DrugTranilast sodium

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 COL1A2

1.15e-08115858CID000005527
DrugAC1NMZ1B

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL27A1 COL1A2

1.27e-0875857CID005034185
Drugstrontium ranelate

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL27A1 COL1A2

1.53e-0877857CID006918182
DrugAC1L18QD

COL4A3 COL4A6 COL24A1 COL9A2 IGF1R COL13A1 COL19A1 COL27A1 ADCY1 ADCY8 COL1A2

3.53e-083258511CID000000213
Drug12(S)-hydroxyeicosatetraenoic acid

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL27A1 ADCY1 ADCY8 COL1A2

3.70e-08189859CID000001413
Drugpirfenidone

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 COL1A2

4.83e-08138858CID000040632
DrugDL-penicillamine

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 COL1A2

5.10e-08139858CID000004727
DrugL-lysyl-L-lysyl-L-lysine

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 EFNB3 COL27A1 COL1A2

1.67e-07162858CID000072363
DrugPPACK

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL27A1 COL1A2

2.21e-07113857CID003036757
DrugAC1L9732

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL27A1 COL1A2

2.34e-07114857CID000439300
Drugkhellin

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 COL1A2

2.53e-07171858CID000003828
DrugAC1L1DD6

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 COL1A2

3.59e-07179858CID000002299
Drugprostacyclin sodium salt

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL27A1 ADCY1 ADCY8 COL1A2

4.00e-07250859CID000000159
DrugSelara

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL27A1 COL1A2

4.39e-07125857CID000150310
Drughyaluronan

COL4A3 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 COL1A2

6.12e-07263859CID000024759
DrugDMSe

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL27A1 COL1A2

6.36e-07132857CID000020796
Drugcandesartan cilexetil

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL27A1 COL1A2

1.20e-06145857CID000002540
Drugcolchine

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 MAPT COL27A1 PKD1 COL1A2

1.65e-063838510CID000002833
DrugAC1Q6PCP

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 COL1A2

2.37e-06230858CID000005267
Drugchondroitin sulfate

COL4A3 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 PODXL2 COL1A2

3.22e-064138510CID000024766
DrugLMWH

COL4A3 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 LIPH COL27A1 ADCY1 ADCY8 RYR2 COL1A2

6.35e-066638512CID000000772
Drugfoscarnet

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL27A1 COL1A2

7.19e-06190857CID000003414
DrugL(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; PC3; HT_HG-U133A

ONECUT2 MAN1A2 ATXN1 MAPT GRM7 RYR2 COL1A2

8.24e-061948575056_UP
DrugAC1L1KMJ

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 PKD1 MARCO COL1A2

1.12e-054768510CID000030956
Drugsilibinin

COL4A3 COL4A6 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 COL1A2

1.14e-05285858CID000005213
Druglosartan

COL4A3 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 COL19A1 COL27A1 COL1A2

1.18e-05378859CID000003961
Drug(2s,5s)-5-Carboxymethylproline

COL4A3 COL4A6 HSPG2 COL24A1 COL9A2 COL13A1 COL27A1 COL1A2

2.29e-05314858CID000447989
Drugnitrendipine

PKD1 EHMT1 ADCY1 ADCY8 RYR2

3.33e-0598855CID000004507
DrugAC1L1FA8

KIFBP GRIN3B ADCY1 ADCY8

3.65e-0550854CID000003150
DrugAC1L1EKQ

GRIN3B GRM7 ADCY1 ADCY8

4.27e-0552854CID000002834
DrugSK&F 82958

ADCY1 ADCY8 RYR2

4.66e-0519853ctd:C071262
Drugglyphosate

COL13A1 SCAP KMT2B DKK1 ATXN1 LIPH EHMT1 MARCO COL1A2

7.49e-05479859ctd:C010974
Drugbaclofen

PKD1 GRIN3B GRM7 ADCY1 ADCY8 RYR2

8.13e-05191856CID000002284
DrugOrlistat; Up 200; 10uM; PC3; HT_HG-U133A

ONECUT2 MAN1A2 NPAS3 PODXL2 GRM7 COL1A2

8.37e-051928566388_UP
DrugPropafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; MCF7; HT_HG-U133A

COL4A3 IGF1R EFNB3 COL19A1 GRM7 AHNAK2

9.37e-051968562871_UP
DrugNAIN

ADCY1 MARCO ADCY8

9.60e-0524853CID000195228
Drug2-propylpentanoic acid; Up 200; 50uM; PC3; HT_HG-U133A

ONECUT2 COL4A6 MAN1A2 EHMT1 MARCO RYR2

9.91e-051988564446_UP
DrugDenatonium benzoate [3734-33-6]; Up 200; 9uM; PC3; HT_HG-U133A

ONECUT2 EFNB3 MAPT SLC19A1 PODXL2 COL1A2

1.02e-041998565061_UP
DrugAC1L9NB5

ZFPM1 ADCY1 ADCY8

1.09e-0425853CID000449609
Drugarabinosyladenine

TRIT1 ACAA1 SLC19A1 COL27A1 PKD1 ZFPM1 GRM7 ADCY1 ADCY8 RYR2 COL1A2

1.23e-047628511CID000000191
DrugAC1L1H5B

ACAA1 AMDHD2 ADCY1 ADCY8

1.99e-0477854CID000003981
Drugdihydrofolate

IGF1R SLC19A1

2.05e-046852ctd:C010920
Diseasesleep disorder (implicated_via_orthology)

IGF1R TFAP2E INSRR

3.48e-0611833DOID:535 (implicated_via_orthology)
Diseasedementia (is_implicated_in)

IGF1R MAPT LRP8

4.64e-0612833DOID:1307 (is_implicated_in)
Diseasecollagen disease (implicated_via_orthology)

COL4A3 COL4A4 COL4A6

4.64e-0612833DOID:854 (implicated_via_orthology)
Diseasebenign familial hematuria (is_implicated_in)

COL4A3 COL4A4

7.82e-062832DOID:0111365 (is_implicated_in)
DiseaseAlport syndrome, recessive type

COL4A3 COL4A4

7.82e-062832C2931254
DiseaseAlport syndrome, dominant type

COL4A3 COL4A4

7.82e-062832C2931253
DiseaseALPORT SYNDROME 2, AUTOSOMAL RECESSIVE

COL4A3 COL4A4

7.82e-062832C4746745
Diseaseautosomal recessive Alport syndrome (is_implicated_in)

COL4A3 COL4A4

7.82e-062832DOID:0110033 (is_implicated_in)
DiseaseThin basement membrane disease

COL4A3 COL4A4

7.82e-062832C0403440
DiseaseBenign familial hematuria

COL4A3 COL4A4

7.82e-062832cv:C0241908
Diseaseautosomal recessive Alport syndrome (implicated_via_orthology)

COL4A3 COL4A4

2.34e-053832DOID:0110033 (implicated_via_orthology)
DiseaseAlport syndrome

COL4A3 COL4A4

2.34e-053832cv:C1567741
DiseaseCollagen IV-related nephropathies

COL4A3 COL4A4

2.34e-053832cv:CN076135
DiseaseHematuria, Benign Familial

COL4A3 COL4A4

4.67e-054832C0241908
DiseaseAlport Syndrome

COL4A3 COL4A4

4.67e-054832C1567741
DiseaseAlport Syndrome, X-Linked

COL4A3 COL4A4

7.77e-055832C1567742
DiseaseAlport Syndrome, Autosomal Dominant

COL4A3 COL4A4

7.77e-055832C1567743
DiseaseAlport Syndrome, Autosomal Recessive

COL4A3 COL4A4

7.77e-055832C1567744
Diseasehypertensive nephropathy

COL4A3 COL4A4

1.16e-046832C0848548
DiseaseEarly Pregnancy Loss

COL4A6 COL9A2 COL13A1 COL1A2

2.59e-04109834C3830362
DiseaseMiscarriage

COL4A6 COL9A2 COL13A1 COL1A2

2.59e-04109834C4552766
DiseaseSpontaneous abortion

COL4A6 COL9A2 COL13A1 COL1A2

2.59e-04109834C0000786
DiseaseAbortion, Tubal

COL4A6 COL9A2 COL13A1 COL1A2

2.59e-04109834C0000822
Diseasealcohol dependence (implicated_via_orthology)

IGF1R INSRR

2.78e-049832DOID:0050741 (implicated_via_orthology)
Diseasemyopathy (implicated_via_orthology)

COL4A3 COL4A4 COL4A6

3.39e-0448833DOID:423 (implicated_via_orthology)
Diseaseinterventricular septum thickness

IGF1R MAPT

3.47e-0410832EFO_0009287
DiseaseDuchenne muscular dystrophy, disease progression measurement

UNCX ADCY1 ADCY8

3.82e-0450833EFO_0008336, MONDO_0010679
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

COL9A2 PKD1 COL1A2

4.54e-0453833C4707243
Diseaseintracranial aneurysm (is_implicated_in)

PKD1 COL1A2

5.07e-0412832DOID:10941 (is_implicated_in)
Diseasedickkopf‐related protein 1 measurement

DKK1 ZFPM1

5.07e-0412832EFO_0010620
DiseaseRespiratory Depression

IGF1R MAPT

5.98e-0413832C0235063
DiseaseConnective Tissue Diseases

COL9A2 PKD1

5.98e-0413832C0009782
DiseaseRespiratory Insufficiency

IGF1R MAPT

5.98e-0413832C0035229
DiseaseRespiratory Failure

IGF1R MAPT

5.98e-0413832C1145670
Diseasebasophil measurement

KIFBP CEBPA ZFPM1

6.54e-0460833EFO_0803539
Diseasevital capacity

HSPG2 MICAL1 IGF1R MAPT IRX1 GRM7 MARCO QSOX2 ADCY8 RYR2 COL1A2

6.78e-0412368311EFO_0004312
Diseasediabetic neuropathy (implicated_via_orthology)

IGF1R INSRR

6.96e-0414832DOID:9743 (implicated_via_orthology)
DiseaseHereditary hearing loss and deafness

COL4A3 COL4A4 COL9A2 ADCY1

7.81e-04146834cv:C0236038
Diseaseinfant head circumference

STRBP PREX1

8.02e-0415832EFO_0004577
Diseaseneuroimaging measurement

SP8 COL24A1 KMT2B MAPT ASCL1 CARMIL1 PKD1 QSOX2 GATAD2B LRP8

8.28e-0410698310EFO_0004346
Diseaseattention deficit hyperactivity disorder, autism spectrum disorder, intelligence

FOXO6 MAPT TSNARE1 NPAS3 PREX1 GATAD2B

9.13e-04398836EFO_0003756, EFO_0003888, EFO_0004337
DiseaseNonorganic psychosis

SP8 SOBP NPAS3

9.84e-0469833C0349204
DiseaseParoxysmal atrial fibrillation

HSPG2 IGF1R ATXN1 MAPT

9.99e-04156834C0235480
Diseasefamilial atrial fibrillation

HSPG2 IGF1R ATXN1 MAPT

9.99e-04156834C3468561
DiseasePersistent atrial fibrillation

HSPG2 IGF1R ATXN1 MAPT

9.99e-04156834C2585653
DiseaseAtrial Fibrillation

HSPG2 IGF1R ATXN1 MAPT

1.10e-03160834C0004238
Diseasecortical thickness

SP8 HSPG2 IGF1R KMT2B MAPT SLC19A1 STRBP PKD1 GATAD2B LRP8

1.12e-0311138310EFO_0004840
Diseaseobsolete aging

COL4A3 COL4A4 CARMIL1 SP6 COL1A2

1.16e-03279835GO_0007568
Diseaseosteochondrodysplasia (is_implicated_in)

HSPG2 COL9A2

1.30e-0319832DOID:2256 (is_implicated_in)
DiseaseLung diseases

IGF1R IRX3 IRX1

1.40e-0378833C0024115
DiseaseMultiple Epiphyseal Dysplasia

HSPG2 COL9A2

1.44e-0320832C0026760
DiseaseQRS duration

SP8 IGF1R NPAS3 IFFO2 ZFPM1

1.55e-03298835EFO_0005055
DiseaseParkinson Disease

IGF1R COL19A1 MAPT

1.80e-0385833C0030567
DiseaseRenal glomerular disease

COL4A3 COL4A4

1.90e-0323832C0268731
DiseaseGlomerulopathy Assessment

COL4A3 COL4A4

1.90e-0323832C4521256
Diseasecreatinine measurement

CERS2 IGF1R FOXO6 UNCX LIPH SLC19A1 SP6 PNPLA7 QSOX2

1.92e-03995839EFO_0004518
Diseasealbuminuria

COL4A3 COL4A4 GRM7

2.39e-0394833EFO_0004285
Diseasediabetes mellitus (implicated_via_orthology)

IGF1R INSRR

2.43e-0326832DOID:9351 (implicated_via_orthology)
Diseasealcohol consumption measurement

ONECUT2 SP8 KIFBP EFNB3 UNCX ATXN1 MAPT SLC19A1 SGPP2 NPAS3

2.52e-0312428310EFO_0007878
Diseaseulcerative colitis

COL13A1 CEBPA BRD2 IFFO2 ADCY8

2.58e-03335835EFO_0000729
DiseasePR interval

HSPG2 COL13A1 CARMIL1 ZFPM1 RYR2 COL1A2

2.75e-03495836EFO_0004462
Diseaseresponse to antineoplastic agent

IFFO2 ADCY8 RYR2

2.77e-0399833GO_0097327
Diseasereticulocyte measurement

CEBPA ATXN1 MAPT SLC19A1 SP6 ZFPM1 SPOCD1 PREX1 ADCY8

2.81e-031053839EFO_0010700

Protein segments in the cluster

PeptideGeneStartEntry
GKASDPAGGGPNHHA

ADCY8

66

P40145
HLGPQSPAAAGGAGL

EP400

236

Q96L91
PGLHGLNGLPGTKGT

COL4A6

1171

Q14031
PGLPGIHGLQGDKGE

COL4A3

1041

Q01955
GPLGHPGEKGEKGNS

COL4A4

161

P53420
GARGPKGNKGDPASH

COL4A4

1066

P53420
GIKGPSGSPGLNGLH

COL4A4

1166

P53420
DLGLGKAGGKSVPHP

ATXN1

341

P54253
AGGGAKSRPLANGHP

CERS2

356

Q96G23
GAHGLADAPLGLPGL

TFAP2E

146

Q6VUC0
HEAKGLPRAAAGAPG

RASAL3

311

Q86YV0
LHGSAGGKQGLLGAP

RAVER1

351

Q8IY67
GGPGGQLPAKAQIHG

HSPG2

1901

P98160
LDGPGAHKEVGGAAP

QSOX2

636

Q6ZRP7
EKHPSLNGGGALNGP

PODXL2

566

Q9NZ53
QHTEEGGGPLGGPLK

TRIT1

206

Q9H3H1
GDPHILVVGDPGLGK

MCM8

446

Q9UJA3
KDGQPLPGEGAGLQH

HMCN2

2206

Q8NDA2
GHGGDPKLSPHKVQG

IMUP

21

Q9GZP8
SGHKAENGPGPGVLV

IGF1R

1321

P08069
DGTGLSQPKGQGHLP

MINDY4B

61

A8MYZ0
LLPAAGPAQFHGEKG

FZD2

16

Q14332
AHGLLLGAPLAGPGV

ZFPM1

876

Q8IX07
GEAGAAGLAPPGHAA

FOXO6

386

A8MYZ6
HIAEAPGSLLPGGKG

NSUN5P2

281

Q63ZY6
PLAATPLGNGLGGLH

ONECUT2

226

O95948
ALGLEPGGGLPQYHK

MICAL1

36

Q8TDZ2
GHLAEALAGQGPAAG

KLC3

46

Q6P597
GPDGKQLHPGPCGLQ

KMT2B

1436

Q9UMN6
GLDPAGPLFNGKPHQ

LIPH

176

Q8WWY8
LNTGIGGHKGPSLAD

GATAD2B

556

Q8WXI9
SDHGGGRPAAAGPLL

PNPLA7

336

Q6ZV29
AGLGKPGELGALQAG

PRSS41

16

Q7RTY9
LHLKFGGAPAGPAGT

DNAH1

1571

Q9P2D7
LGAPGPAPGLAKGSH

ADCY1

81

Q08828
GHNGLDGLKGQPGAP

COL1A2

181

P08123
PRGLPGLKGHNGLQG

COL1A2

1016

P08123
GLKGHNGLQGLPGIA

COL1A2

1021

P08123
HGNPGIKGERGPKGN

COL28A1

256

Q2UY09
LRPAADGQPSGGGHK

ASCL1

66

P50553
DGQPSGGGHKSAPKQ

ASCL1

71

P50553
EKGDHGLPGLQGHPG

COL20A1

1106

Q9P218
LNGENGLKGDLGPHG

COL19A1

356

Q14993
LGPADAQLHGPAAAG

LINC00315

16

P59091
LPGPGSALKGLGAAH

CEBPA

246

P49715
HQGKPGPKGDVGASG

COL9A2

206

Q14055
GHQGLAGVPGQPGTK

COL9A2

331

Q14055
GDPGLSPGKAHDGAK

COL27A1

676

Q8IZC6
IKGEQGAPGLQGHKG

MARCO

146

Q9UEW3
NAVALGGLPPGGGSH

IFFO2

136

Q5TF58
GKGAKNPGVFLIHGP

MAN1A2

81

O60476
AKFGGVHLALLPPGN

INSRR

871

P14616
LGGLFPVHAKGPSGV

GRM7

51

Q14831
SDGGGAVPKLHPGLP

CARMIL1

1206

Q5VZK9
PGKHGAKGAPGIAVA

COL13A1

326

Q5TAT6
KLPGQEGAAAPGEAG

GPRIN1

641

Q7Z2K8
AIKNLPPPLGGAAGH

DKK1

41

O94907
GAAHSLEPGKENLPG

EFNB3

191

Q15768
EAGPKGPGGVQAHGD

SCAP

691

Q12770
GLPGAGLFGPKNDLE

RYR2

1321

Q92736
SLPGHAAKTLPGGAG

EHMT1

146

Q9H9B1
AKAGQEELGPGPAGA

PERM1

221

Q5SV97
GPGAGDHALGLPAEV

KIFBP

66

Q96EK5
AAAADPLLGGQGPAK

LRP8

31

Q14114
PGDLVGLQHDAGPGA

PKD1

711

P98161
LGLPGAAGHPAAAAA

IRX3

436

P78415
NGLGHEFLNDGPKPG

MSRB1

76

Q9NZV6
AAAPAGGKAPGQHGG

HMG20B

11

Q9P0W2
LALALGPGSAGGHPQ

GRIN3B

11

O60391
VNPLGGAVALGHPLG

ACAA1

366

P09110
GPHLDKGDFGQLSGP

SPATA31A6

106

Q5VVP1
AAAGGLQGAPHGKPK

IRX1

301

P78414
GPHLDKGDFGQLSGP

SPATA31A7

106

Q8IWB4
HPKPGAAGSVGAGLI

PREX1

1551

Q8TCU6
LASGILLPGGPGLHD

STRBP

271

Q96SI9
LSASPRDKHPGNGGG

NPAS3

751

Q8IXF0
AAGGQHLLGPPDGAK

SP6

176

Q3SY56
PAGANGLAGHPLKPL

SOWAHB

471

A6NEL2
QPGAGVHPKADGALK

SPRY3

116

O43610
AAALPGSLHPAAGGL

SP8

226

Q8IXZ3
PGVEHLPAANGKGGE

SGPP2

46

Q8IWX5
TPHNKLPGEGNAGLL

BRD2

6

P25440
LPEGHLPEGAGLKGH

AHNAK2

1066

Q8IVF2
LPEGPVSEGAGLKGH

AHNAK2

1561

Q8IVF2
LPEGQVPEGAGLKGH

AHNAK2

1891

Q8IVF2
LLEGPVPEGAGLKGH

AHNAK2

3541

Q8IVF2
QGDKGLKGHPGLPGL

COL24A1

566

Q17RW2
HGADGISGNPGKIGP

COL24A1

1296

Q17RW2
GPHLDKGDFGQLSGP

SPATA31A3

106

Q5VYP0
RLAHKAENLGGPGAG

ZNF865

1036

P0CJ78
AHGPSPGSGKPQALA

TSNARE1

206

Q96NA8
GPHLDKGDFGQLSGP

SPATA31A1

106

Q5TZJ5
GPHLDKGDFGQLSGP

SPATA31A5

106

Q5VU36
APGDSAAAGGKPSGH

SOBP

566

A7XYQ1
PLKGERPGAAHQAGP

SYCE1

311

Q8N0S2
GAISHGQAGGQLPPK

SPOCD1

486

Q6ZMY3
NPGPGGKLGHALRVA

SLC19A1

231

P41440
LHQEGPPLKGAGGKE

MAPT

196

P10636
QHPDGGPGGKALGSD

ZNF503

296

Q96F45
PVSKAAAGGAPHIGF

PRRT1B

86

A0A1B0GWB2
PPAAKGPGAHASGAA

UNCX

251

A6NJT0
KDAAPGGGHHQAGPG

GOLGA8CP

466

A6NN73
NDKHLSVGPGQGPGS

KIAA1522

26

Q9P206
PVKSGGPHGAGVLGL

AMDHD2

126

Q9Y303