Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	carbon-sulfur lyase activity	CENPVL2 CENPVL3 CENPVL1	2.43e-05	16	72	3	GO:0016846
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	HINFP ZNF131 ZBTB7A ZNF311 MYBBP1A ZNF473 KLF6 ZNF423 ZNF813 ZBTB9 ZNF521 OSR2 ZNF740 ZBTB1 CASZ1 ZNF574	4.99e-05	1459	72	16	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HINFP ZNF131 ZBTB7A ZNF311 MYBBP1A ZNF473 KLF6 ZNF423 ZNF813 ZBTB9 ZNF521 ZNF740 ZBTB1 ZNF574	1.22e-04	1244	72	14	GO:0000978
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	HINFP ZNF131 ZBTB7A ZNF311 ZNF473 KLF6 ZNF423 ZNF813 ZBTB9 ZNF521 OSR2 ZNF740 ZBTB1 CASZ1 ZNF574	1.28e-04	1412	72	15	GO:0000981
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	HINFP ZNF131 ZBTB7A ZNF311 MYBBP1A ZNF473 KLF6 ZNF423 ZNF813 ZBTB9 ZNF521 ZNF740 ZBTB1 ZNF574	1.53e-04	1271	72	14	GO:0000987
GeneOntologyMolecularFunction	phosphatidylinositol-3-phosphate binding	ZFYVE28 PLEKHF1 SNX27	6.92e-04	48	72	3	GO:0032266
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	HINFP ZNF131 ZNF473 KLF6 ZNF521 OSR2 CASZ1 ZNF574	9.01e-04	560	72	8	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	HINFP ZNF131 ZNF473 KLF6 ZNF521 OSR2 CASZ1 ZNF574	9.64e-04	566	72	8	GO:0001216
GeneOntologyCellularComponent	early endosome membrane	PIKFYVE ZFYVE28 RBSN ZFYVE9 ZFYVE16 SNX27 RUFY1	6.33e-06	212	69	7	GO:0031901
GeneOntologyCellularComponent	early endosome	PIKFYVE ZFYVE28 RBSN ZFYVE9 ZFYVE16 PLEKHF1 SNX27 RUFY1	1.81e-04	481	69	8	GO:0005769
Domain	FYVE	PIKFYVE ZFYVE28 RBSN ZFYVE9 ZFYVE16 PLEKHF1 ZFYVE21 RUFY1	9.21e-14	29	69	8	PF01363
Domain	FYVE	PIKFYVE ZFYVE28 RBSN ZFYVE9 ZFYVE16 PLEKHF1 ZFYVE21 RUFY1	9.21e-14	29	69	8	SM00064
Domain	Znf_FYVE-rel	PIKFYVE ZFYVE28 RBSN ZFYVE9 ZFYVE16 PLEKHF1 ZFYVE21 RUFY1	3.84e-13	34	69	8	IPR017455
Domain	Znf_FYVE	PIKFYVE ZFYVE28 RBSN ZFYVE9 ZFYVE16 PLEKHF1 ZFYVE21 RUFY1	1.02e-12	38	69	8	IPR000306
Domain	ZF_FYVE	PIKFYVE ZFYVE28 RBSN ZFYVE9 ZFYVE16 PLEKHF1 ZFYVE21 RUFY1	1.60e-12	40	69	8	PS50178
Domain	ZINC_FINGER_C2H2_2	HINFP ZNF131 ZBTB7A ZNF311 RBSN ZNF155 ZNF473 KLF6 ZNF423 ZFP64 ZNF813 ZBTB9 ZNF521 OSR2 ZNF740 ZBTB1 REPIN1 CASZ1 ZNF574	2.91e-11	775	69	19	PS50157
Domain	ZINC_FINGER_C2H2_1	HINFP ZNF131 ZBTB7A ZNF311 RBSN ZNF155 ZNF473 KLF6 ZNF423 ZFP64 ZNF813 ZBTB9 ZNF521 OSR2 ZNF740 ZBTB1 REPIN1 CASZ1 ZNF574	3.04e-11	777	69	19	PS00028
Domain	zf-C2H2	HINFP ZNF131 ZBTB7A ZNF311 ZNF155 ZNF473 KLF6 ZNF423 ZFP64 ZNF813 ZBTB9 ZNF521 OSR2 ZNF740 ZBTB1 REPIN1 CASZ1 ZNF574	4.18e-11	693	69	18	PF00096
Domain	Znf_C2H2-like	HINFP ZNF131 ZBTB7A ZNF311 RBSN ZNF155 ZNF473 KLF6 ZNF423 ZFP64 ZNF813 ZBTB9 ZNF521 OSR2 ZNF740 ZBTB1 REPIN1 CASZ1 ZNF574	4.60e-11	796	69	19	IPR015880
Domain	Znf_C2H2	HINFP ZNF131 ZBTB7A ZNF311 RBSN ZNF155 ZNF473 KLF6 ZNF423 ZFP64 ZNF813 ZBTB9 ZNF521 OSR2 ZNF740 ZBTB1 REPIN1 CASZ1 ZNF574	5.57e-11	805	69	19	IPR007087
Domain	ZnF_C2H2	HINFP ZNF131 ZBTB7A ZNF311 RBSN ZNF155 ZNF473 KLF6 ZNF423 ZFP64 ZNF813 ZBTB9 ZNF521 OSR2 ZNF740 ZBTB1 REPIN1 CASZ1 ZNF574	5.94e-11	808	69	19	SM00355
Domain	-	HINFP ZNF131 ZBTB7A ZNF311 ZNF155 ZNF473 KLF6 ZNF423 ZFP64 ZNF813 ZBTB9 ZNF521 OSR2 ZNF740 ZBTB1 REPIN1 ZNF574	2.83e-10	679	69	17	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	HINFP ZNF131 ZBTB7A ZNF311 ZNF155 ZNF473 KLF6 ZNF423 ZFP64 ZNF813 ZBTB9 ZNF521 OSR2 ZNF740 ZBTB1 REPIN1 ZNF574	3.96e-10	694	69	17	IPR013087
Domain	Znf_FYVE_PHD	PIKFYVE ZFYVE28 RBSN ZFYVE9 ZFYVE16 PLEKHF1 ZFYVE21 RUFY1	6.78e-08	147	69	8	IPR011011
Domain	-	PIKFYVE ZFYVE28 RBSN ZFYVE9 ZFYVE16 MYCBP2 ZNF423 PLEKHF1 ZFYVE21 ZNF521 RUFY1	7.13e-07	449	69	11	3.30.40.10
Domain	Znf_RING/FYVE/PHD	PIKFYVE ZFYVE28 RBSN ZFYVE9 ZFYVE16 MYCBP2 ZNF423 PLEKHF1 ZFYVE21 ZNF521 RUFY1	8.85e-07	459	69	11	IPR013083
Domain	zf-C2H2_6	ZNF311 ZNF155 ZNF473 ZNF423 ZFP64 ZNF813 ZNF521 OSR2 ZNF574	2.24e-06	314	69	9	PF13912
Domain	DUF3480	ZFYVE9 ZFYVE16	1.35e-05	2	69	2	PF11979
Domain	DUF3480	ZFYVE9 ZFYVE16	1.35e-05	2	69	2	IPR022557
Domain	Znf_FYVE_endofin	ZFYVE9 ZFYVE16	1.35e-05	2	69	2	IPR017165
Domain	LIM	TRIP6 PRICKLE1 CRIP3 ZYX	1.23e-04	69	69	4	PF00412
Domain	-	TRIP6 PRICKLE1 CRIP3 ZYX	1.30e-04	70	69	4	2.10.110.10
Domain	Znf_LIM	TRIP6 PRICKLE1 CRIP3 ZYX	1.38e-04	71	69	4	IPR001781
Domain	LIM_DOMAIN_1	TRIP6 PRICKLE1 CRIP3 ZYX	1.38e-04	71	69	4	PS00478
Domain	LIM_DOMAIN_2	TRIP6 PRICKLE1 CRIP3 ZYX	1.38e-04	71	69	4	PS50023
Domain	LIM	TRIP6 PRICKLE1 CRIP3 ZYX	1.38e-04	71	69	4	SM00132
Domain	Filamin	AREL1 MYCBP2	7.24e-04	11	69	2	PF00630
Domain	FILAMIN_REPEAT	AREL1 MYCBP2	7.24e-04	11	69	2	PS50194
Domain	Filamin/ABP280_rpt	AREL1 MYCBP2	7.24e-04	11	69	2	IPR001298
Domain	Filamin/ABP280_repeat-like	AREL1 MYCBP2	7.24e-04	11	69	2	IPR017868
Domain	BTB	ZNF131 ZBTB7A ZBTB9 ZBTB1	1.40e-03	131	69	4	PF00651
Domain	BTB	ZNF131 ZBTB7A ZBTB9 ZBTB1	2.91e-03	160	69	4	PS50097
Domain	zf-DHHC	ZDHHC22 ZDHHC7	3.24e-03	23	69	2	PF01529
Domain	DHHC	ZDHHC22 ZDHHC7	3.82e-03	25	69	2	PS50216
Domain	Znf_DHHC_palmitoyltrfase	ZDHHC22 ZDHHC7	3.82e-03	25	69	2	IPR001594
Domain	BTB	ZNF131 ZBTB7A ZBTB9 ZBTB1	4.43e-03	180	69	4	SM00225
Domain	BTB/POZ_dom	ZNF131 ZBTB7A ZBTB9 ZBTB1	4.88e-03	185	69	4	IPR000210
Domain	SKP1/BTB/POZ	ZNF131 ZBTB7A ZBTB9 ZBTB1	5.26e-03	189	69	4	IPR011333
Domain	TPR-like_helical_dom	SART3 TRANK1 P3H4 WDTC1	1.08e-02	233	69	4	IPR011990
Pubmed	Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow.	CENPVL2 CENPVL3 CENPVL1	1.77e-07	6	73	3	27250503
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	HINFP ZNF131 ZBTB7A ZNF473 KLF6 TRIP6 ZNF423 ZFP64 ZDHHC7 ZNF740 ZYX	9.55e-07	808	73	11	20412781
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	PIKFYVE RBSN KLF6 ZFP64 ZNF521 OSR2 ZDHHC7 CRIP3 ZBTB1 ZYX	2.27e-06	709	73	10	22988430
Pubmed	Evi3, a common retroviral integration site in murine B-cell lymphoma, encodes an EBFAZ-related Krüppel-like zinc finger protein.	ZNF423 ZNF521	4.35e-06	2	73	2	12393497
Pubmed	Inhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARA.	ZFYVE9 ZFYVE16	4.35e-06	2	73	2	16775010
Pubmed	Direct transcriptional repression of Zfp423 by Zfp521 mediates a bone morphogenic protein-dependent osteoblast versus adipocyte lineage commitment switch.	ZNF423 ZNF521	1.30e-05	3	73	2	24891617
Pubmed	SH3 domain-dependent interaction of the proto-oncogene product Vav with the focal contact protein zyxin.	ZYX VAV1	1.30e-05	3	73	2	8622875
Pubmed	ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies.	ZNF423 ZNF521	1.30e-05	3	73	2	26788497
Pubmed	Prognostic value of the Stanniocalcin-2/PAPP-A/IGFBP-4 axis in ST-segment elevation myocardial infarction.	IGFBP4 STC2	1.30e-05	3	73	2	29712555
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZBTB7A TRIP6 COQ8B ZBTB9 OAS3 ZNF740 REPIN1 P3H4 VAV1 ZNF574 WDTC1	2.04e-05	1116	73	11	31753913
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF131 HAUS6 ZFYVE16 MYCBP2 ZBTB9 RUFY1 ZBTB1	2.84e-05	418	73	7	34709266
Pubmed	FBI-1 enhances transcription of the nuclear factor-kappaB (NF-kappaB)-responsive E-selectin gene by nuclear localization of the p65 subunit of NF-kappaB.	ZBTB7A NFKBIB	4.33e-05	5	73	2	15917220
Pubmed	Early hematopoietic zinc finger protein (EHZF), the human homolog to mouse Evi3, is highly expressed in primitive human hematopoietic cells.	ZNF423 ZNF521	4.33e-05	5	73	2	14630787
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	SART3 ZNF131 TRANK1 IGFBP4 MYCBP2 PRICKLE1 ZNF423 ZDHHC7 CRIP3 ZBTB1 REPIN1	4.42e-05	1215	73	11	15146197
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	MYBBP1A ZFYVE9 TRIP6 ZFYVE16 MYCBP2 PTPRN SNX27 ROCK1 ZYX FAN1	6.63e-05	1049	73	10	27880917
Pubmed	Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.	ECM1 NOD2	1.21e-04	8	73	2	18438406
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	PIKFYVE ZFYVE16 MYCBP2 DHCR7 ZDHHC7 ROCK1 ESPL1 P3H4	1.51e-04	733	73	8	34672954
Pubmed	Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers.	TRIP6 ZYX	1.55e-04	9	73	2	11782456
Pubmed	Endofin acts as a Smad anchor for receptor activation in BMP signaling.	ZFYVE9 ZFYVE16	2.36e-04	11	73	2	17356069
Pubmed	Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.	ZNF131 ZFYVE9 ZNF473 TRIP6 ZFP64 ZDHHC22 ZBTB9 RUFY1 ZBTB1 ZYX GPATCH2L	2.47e-04	1477	73	11	31515488
Pubmed	Loss of migfilin expression has no overt consequences on murine development and homeostasis.	TRIP6 ZYX	3.34e-04	13	73	2	21224394
Pubmed	The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity.	TRIP6 ZYX	3.34e-04	13	73	2	22286099
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	PIKFYVE RBSN ZFYVE9 ZFYVE16 SNX27	3.40e-04	285	73	5	34369648
Pubmed	Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation.	HAUS6 MYBBP1A ZNF740 GPATCH2L ZNF574	4.63e-04	305	73	5	21244100
Pubmed	Zfp423/OAZ participates in a developmental switch during olfactory neurogenesis.	ZNF423 ZNF521	5.12e-04	16	73	2	17521568
Pubmed	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.	ZNF131 ZNF155	5.79e-04	17	73	2	7557990
Pubmed	Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.	TRIP6 NFKBIB	6.51e-04	18	73	2	7776974
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	HAUS6 RBSN MYBBP1A ZNF740 ZYX ZNF574	6.67e-04	503	73	6	16964243
Pubmed	PDGFRα controls the balance of stromal and adipogenic cells during adipose tissue organogenesis.	ZNF423 ZNF521	7.26e-04	19	73	2	28049691
Pubmed	Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.	ZBTB7A OSR2	7.26e-04	19	73	2	30385546
Pubmed	An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.	PIKFYVE TRIP6 ZFP64 ZDHHC22 RUFY1 ZYX	7.46e-04	514	73	6	29892012
Pubmed	Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins.	ZDHHC22 ZDHHC7	8.06e-04	20	73	2	16647879
Pubmed	USP15 Deubiquitinates TUT1 Associated with RNA Metabolism and Maintains Cerebellar Homeostasis.	SART3 MYCBP2	8.89e-04	21	73	2	32839293
Pubmed	A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex.	MYBBP1A MYCBP2	8.89e-04	21	73	2	24923560
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	MYBBP1A ZNF473 DHCR7 ZNF813 ZNF740 CENPVL1 REPIN1 CASZ1 ZNF574	9.16e-04	1203	73	9	29180619
Pubmed	Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.	ZNF473 TRIP6 PTPRN DHCR7 ZFP64 ZBTB1 ZYX	9.41e-04	742	73	7	26871637
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	HAUS6 MYBBP1A TRIP6 MYCBP2 RUFY1 ZYX	1.05e-03	549	73	6	38280479
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	RBSN TRIP6 ZFYVE16 MYCBP2 STC2 STXBP5 ZBTB9 SNX27	1.22e-03	1007	73	8	34597346
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	PIKFYVE ZBTB1 FAN1	1.31e-03	102	73	3	10231032
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	AREL1 TRANK1 ZFYVE16	1.39e-03	104	73	3	9205841
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	ZBTB7A MYBBP1A TRIP6 ZFP64 ZBTB9 ZNF740	1.42e-03	583	73	6	29844126
Pubmed	Quantitative Proteomics Reveals the Essential Roles of Stromal Interaction Molecule 1 (STIM1) in the Testicular Cord Formation in Mouse Testis.	MYBBP1A NFKBIB	1.47e-03	27	73	2	26199344
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	HAUS6 TRIP6 NFKBIB ESPL1 ZBTB1 ZYX GPATCH2L WDTC1	1.48e-03	1038	73	8	26673895
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	HAUS6 MYCBP2 ZBTB9 ESPL1	1.71e-03	242	73	4	34011540
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	SART3 TRIP6 PTPRN ZNF423 ECM1 ZYX	1.76e-03	608	73	6	16713569
Pubmed	PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.	SART3 TRIP6 MYCBP2 PRICKLE1	1.84e-03	247	73	4	32989298
Pubmed	Activation of Wnt signaling reduces ipsilaterally projecting retinal ganglion cells in pigmented retina.	OSR2 GFRA2	1.94e-03	31	73	2	30254141
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	AREL1 MYBBP1A ZNF473 SNX27 ROCK1 ESPL1 REPIN1 GPATCH2L	1.95e-03	1084	73	8	11544199
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	KLF6 PTPRN WNT6 GFRA2	1.95e-03	251	73	4	29031500
Pubmed	An Approach to Spatiotemporally Resolve Protein Interaction Networks in Living Cells.	RBSN SNX27	2.07e-03	32	73	2	28388416
Interaction	ANKFY1 interactions	RBSN ZFYVE9 ZFYVE16 SNX27 ROCK1 LTA4H RUFY1 VAV1	1.77e-06	236	71	8	int:ANKFY1
Interaction	FAM124A interactions	ZFP64 SNX27 ROCK1 ZYX	2.06e-05	46	71	4	int:FAM124A
Interaction	EEA1 interactions	HAUS6 ZFYVE9 ZFYVE16 MYCBP2 SNX27 RUFY1	2.29e-05	162	71	6	int:EEA1
Interaction	HDAC1 interactions	ZBTB7A HAUS6 MYBBP1A KLF6 ZFYVE16 MYCBP2 ZNF423 ZFP64 ZBTB9 ZNF521 RUFY1 ZBTB1 REPIN1 CASZ1	2.70e-05	1108	71	14	int:HDAC1
Cytoband	Xp11.22	CENPVL2 CENPVL3 CENPVL1	9.03e-05	54	73	3	Xp11.22
Cytoband	14q24.3	AREL1 ZDHHC22 GPATCH2L	4.52e-04	93	73	3	14q24.3
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	LIPE ZNF155 ZNF473 NFKBIB COQ8B ZNF813 SPRED3 ZNF574	6.10e-04	1192	73	8	chr19q13
Cytoband	19q13.2	LIPE COQ8B ZNF574	2.32e-03	164	73	3	19q13.2
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	PIKFYVE ZFYVE28 RBSN ZFYVE9 ZFYVE16 PLEKHF1 ZFYVE21 RUFY1	2.00e-14	31	52	8	81
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	HINFP ZNF131 ZBTB7A ZNF311 ZNF155 ZNF473 KLF6 ZNF423 ZFP64 ZNF813 ZBTB9 ZNF521 OSR2 ZNF740 ZBTB1 REPIN1 CASZ1 ZNF574	5.88e-13	718	52	18	28
GeneFamily	LIM domain containing	TRIP6 PRICKLE1 CRIP3 ZYX	2.46e-05	59	52	4	1218
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	ZNF131 ZBTB7A ZBTB9 ZBTB1	5.93e-04	134	52	4	861
GeneFamily	Zinc fingers DHHC-type\|Ankyrin repeat domain containing	ZDHHC22 ZDHHC7	2.15e-03	24	52	2	76
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Intermediate\|10w / Sample Type, Dataset, Time_group, and Cell type.	ZFYVE28 ZBTB9 ZNF521 ESPL1 CASZ1 WDTC1	9.51e-07	200	73	6	e5a8647c47a49c8c90c78d681193946de103d8ff
ToppCell	mild-unassigned\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	AREL1 PLEKHF1 NFKBIB ZFYVE21 ZNF813	1.37e-05	186	73	5	5b2e1a58916f392fa1156bf9210df528775248ff
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF131 ZBTB7A KLF6 MYCBP2 ROCK1	1.40e-05	187	73	5	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	MatrixFB-Fibroblast-C\|MatrixFB / shred on cell class and cell subclass (v4)	ZFYVE28 IGFBP4 STC2 ZNF423 OSR2	1.52e-05	190	73	5	d0106f7a21292f0b96ce4337ec3efbb1bd78dd0a
ToppCell	distal-Endothelial-Bronchial_Vessel_2-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	YPEL4 LIPE STC2 DHCR7 ZBTB9	1.80e-05	197	73	5	9fcfbfbe78e8fe90c76eb37a58ed9dc8ece652a1
ToppCell	Sigmoid-(1)_T_cell-(14)_Tcm\|Sigmoid / shred on region, Cell_type, and subtype	IGFBP4 NFKBIB SNX27 CRIP3 VAV1	1.89e-05	199	73	5	ec454fa22fb7f50a947bdf4c4bb6f0ba13f62b4c
ToppCell	Sigmoid-T_cell-Tcm\|T_cell / Region, Cell class and subclass	IGFBP4 NFKBIB SNX27 CRIP3 VAV1	1.89e-05	199	73	5	acdf95f4d58df47690f4ae254245bc618f9ac07e
ToppCell	Sigmoid-T_cell-Tcm\|Sigmoid / Region, Cell class and subclass	IGFBP4 NFKBIB SNX27 CRIP3 VAV1	1.89e-05	199	73	5	f7c729eaa3c8fd5a05cb6f79cac9b8f199c8092b
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	KLF6 MYCBP2 OAS3 ROCK1 ZBTB1	1.94e-05	200	73	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRICKLE1 ZNF423 ZNF521 OSR2 ECM1	1.94e-05	200	73	5	fb53be20392a8309a7393774c774a1b1aec6e676
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ZBTB7A TRIP6 STC2 ZFP64 EVPL ZBTB1 ZNF574	1.14e-06	173	71	7	5987_DN
Drug	alpha-estradiol; Up 200; 0.01uM; HL60; HT_HG-U133A	ZNF155 KLF6 STC2 PLEKHF1 NFKBIB OAS3 NOD2	2.63e-06	196	71	7	1151_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IGFBP4 KLF6 TRIP6 STC2 ZFP64 ZBTB1	1.62e-05	172	71	6	4112_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ZFYVE9 TRIP6 STC2 ZFP64 EVPL ZBTB1	1.73e-05	174	71	6	5693_DN
Drug	AC1OAGFW	PIKFYVE RBSN ZFYVE9 ZFYVE16 EVPL RUFY1	2.38e-05	184	71	6	CID006857352
Drug	Rifabutin [72559-06-9]; Down 200; 4.8uM; MCF7; HT_HG-U133A	ZFYVE9 IGFBP4 STC2 OAS3 EVPL ZBTB1	2.38e-05	184	71	6	4349_DN
Drug	Norethynodrel [68-23-5]; Up 200; 13.4uM; PC3; HT_HG-U133A	SART3 ZFYVE16 ZFYVE21 EVPL ECM1 ZYX	3.30e-05	195	71	6	1818_UP
Drug	GSK-3 Inhibitor IX; Up 200; 0.5uM; MCF7; HT_HG-U133A	HINFP ZNF131 ZFYVE9 ZNF473 NFKBIB P3H4	3.30e-05	195	71	6	7101_UP
Drug	clozapine; Down 200; 10uM; MCF7; HT_HG-U133A	HINFP ZNF131 ZNF473 EVPL ZYX VAV1	3.39e-05	196	71	6	6988_DN
Drug	3-Acetamidocoumarin [779-30-6]; Up 200; 19.6uM; HL60; HT_HG-U133A	ZFYVE9 KLF6 GPATCH2L ZNF574 WDTC1 NOD2	3.39e-05	196	71	6	2941_UP
Drug	Felbinac [5728-52-9]; Down 200; 18.8uM; HL60; HT_HG-U133A	ZFYVE9 ZNF155 ZNF473 NFKBIB ZBTB1 WDTC1	3.69e-05	199	71	6	3061_DN
Drug	Ethynylestradiol 3-methyl ether [72-33-3]; Down 200; 12.8uM; MCF7; HT_HG-U133A	ZFYVE9 KLF6 ZFP64 NFKBIB GPATCH2L WDTC1	3.69e-05	199	71	6	3346_DN
Disease	hypertension	STXBP5 ZNF423 OAS3 ODAD2 CRIP3 CASZ1	7.69e-05	307	68	6	EFO_0000537
Disease	Nephritis, Interstitial	DHCR7 FAN1	1.40e-03	24	68	2	C0027707

Protein segments in the cluster

Peptide	Gene	Start	Entry
DCAVDHHFRFCLLLR	NKAPP1	86	Q8N9T2
TSTHFHCLRCRFRCT	CASZ1	1511	Q86V15
DCSCRLCRKKQHRHF	CENPVL1	156	A0A0U1RR11
THRCLRDEHRCASKY	DHCR7	441	Q9UBM7
CGNKFSIRNRRHHCR	RBSN	166	Q9H1K0
RRQLLAHFHCLSCDR	QRICH2	1416	Q9H0J4
VCRTKHLHLRCSVDF	LTA4H	16	P09960
CKAPFTVIRRKHHCR	ZFYVE28	826	Q9HCC9
SAHGCLFDRRLCSHL	PTPRN	36	Q16849
LHLACRVGAHACARA	NFKBIB	131	Q15653
RLHRALKASEHACAA	EVPL	691	Q92817
TCDICHKAFRRQDHL	OSR2	201	Q8N2R0
ARIFTHHLCRARRYC	MYBBP1A	876	Q9BQG0
RHHAELLKPRCSACD	PRICKLE1	181	Q96MT3
DCSEKFTTFRRRHHC	PIKFYVE	166	Q9Y2I7
LEHCRRFCWSRHHDK	ESPL1	256	Q14674
DCSCRLCRKKQHRHF	CENPVL2	156	P0DPI3
DHLCRSRLADFHANC	GFRA2	261	O00451
DCSCRLCRKKQHRHF	CENPVL3	156	A0A0U1RRI6
RLTLHSRGCFHACIS	AREL1	246	O15033
FLACAHLRAHIACRD	COQ8B	496	Q96D53
HRFCLKCERCHSILS	CRIP3	26	Q6Q6R5
DLHKCIARCHFARSR	HAUS6	161	Q7Z4H7
KRRSDFTHLAEHTCC	GPATCH2L	46	Q9NWQ4
CHCRSHTNRLECAKL	ECM1	221	Q16610
CSHCSKRFATERLLR	HINFP	231	Q9BQA5
HCRKALHRAVQCTSD	SART3	526	Q15020
RCCLAHLLHKSRYVA	LIPE	381	Q05469
ILRCLHENCVHKASR	OAS3	441	Q9Y6K5
HRRHSALCIPEAKCA	OTOG	2421	Q6ZRI0
SGVCRHLAADFRHCR	FAN1	941	Q9Y2M0
FSALTRRHHCRKCGF	PLEKHF1	166	Q96S99
RRHHCRKCGFVVCAE	PLEKHF1	171	Q96S99
SVGCARCKHVHAALR	RASL10B	176	Q96S79
NKLRHHLAEAISRCC	ODAD2	936	Q5T2S8
CEKEFSISRRKHHCR	RUFY1	651	Q96T51
LCTDCDRFLHLHRRT	MYCBP2	4281	O75592
CSAHDRRCLQKHFAK	IGFBP4	131	P22692
HSLKFCRERVTFCHL	STXBP5	136	Q5T5C0
ITHRKSHIRDGAFCC	REPIN1	531	Q9BWE0
CHLKAHFRLARCLFE	WDTC1	431	Q8N5D0
HCIEDFHRKFAPRCS	TRIP6	386	Q15654
FCRVCARVTLRHDHH	ZDHHC22	96	Q8N966
CARWCLARSLRKHFH	NOD2	706	Q9HC29
CAHHFCRRLNKSFVD	SLC36A1	101	Q7Z2H8
HRLLRDSEAFCHANC	P3H4	66	Q92791
AHALRHRFGCISRKC	STC2	111	O76061
AEEAARCVHCRALFR	SPRED3	291	Q2MJR0
CHRCRASAHKECLGR	VAV1	546	P15498
CSRLFKHKRSRDRHI	ZNF521	151	Q96K83
RFVHRLERRHKCSIC	ZNF574	486	Q6ZN55
RLAVRSHTRTECKCH	WNT6	211	Q9Y6F9
HCACDSRRKGHVITA	SNX27	431	Q96L92
VFNRKRNLVCHRRCH	ZNF813	251	Q6ZN06
CRRCHVKCHRDHLDK	ROCK1	1261	Q13464
ERDHRRKHFCNLCGK	ZBTB1	571	Q9Y2K1
RFRVHACFLRHRDLC	ZBTB9	446	Q96C00
HRTYSCVHCRAHLAK	YPEL4	26	Q96NS1
LDGHVLCRKCHTARA	ZYX	556	Q15942
CDKSFHQRSALNRHC	ZNF155	321	Q12901
KFDFLTRKHHCRRCG	ZFYVE21	56	Q9BQ24
ERAHHCSICKRCIRK	ZDHHC7	141	Q9NXF8
CHERFARNSTLKCHL	ZNF131	361	P52739
CSRLFKHKRSRDRHI	ZNF423	171	Q2M1K9
NCEHFHRPLRRCEAK	TRANK1	2161	O15050
RCHQCFSRTDRLLRH	ZNF740	161	Q8NDX6
RTCHVCHRHSFEAKL	ZMYND15	311	Q9H091
RVHSRVHCKDRPFKC	ZFP64	511	Q9NTW7
RFTFTKRRHHCRACG	ZFYVE9	711	O95405
CCKTFVRSDHLHRHL	ZBTB7A	471	O95365
CQVKFTFTKRRHHCR	ZFYVE16	756	Q7Z3T8
TFTKRRHHCRACGKV	ZFYVE16	761	Q7Z3T8
CGKAFRHNCKRRAHE	ZNF311	476	Q5JNZ3
RCQKAFRCHSSLSRH	ZNF473	846	Q8WTR7
KCSHCDRCFSRSDHL	KLF6	261	Q99612