Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	DNHD1 MYH1 MYH2 MYH4 MYH8 SETX DHX37 VPS4A ZGRF1 RNF213 YTHDC2 RFC4 NLRP3 ACSL1 FBH1 RECQL4 HELZ ATP1B1 ATP2A3 ABCG5 ALPL	6.12e-09	614	149	21	GO:0140657
GeneOntologyMolecularFunction	helicase activity	SETX DHX37 ZGRF1 YTHDC2 RFC4 FBH1 RECQL4 HELZ	2.49e-05	158	149	8	GO:0004386
GeneOntologyMolecularFunction	ATP hydrolysis activity	MYH4 MYH8 DHX37 VPS4A RNF213 YTHDC2 RFC4 NLRP3 FBH1 RECQL4 ATP2A3 ABCG5 ALPL	2.74e-05	441	149	13	GO:0016887
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	SETMAR SETX DHX37 ZGRF1 POLE YTHDC2 RFC4 TEP1 HARS2 POLR3B ALKBH8 FBH1 RECQL4 HELZ TARS1	9.92e-05	645	149	15	GO:0140640
GeneOntologyMolecularFunction	DNA helicase activity	SETX ZGRF1 RFC4 FBH1 RECQL4	9.94e-05	62	149	5	GO:0003678
GeneOntologyMolecularFunction	microfilament motor activity	MYH1 MYH2 MYH4 MYH8	1.80e-04	38	149	4	GO:0000146
GeneOntologyBiologicalProcess	regulation of CD4-positive, alpha-beta T cell differentiation	TNFSF18 BCL6 NLRP3 SOCS5 SMAD7 NCKAP1L	1.41e-05	73	148	6	GO:0043370
GeneOntologyBiologicalProcess	negative regulation of T-helper cell differentiation	TNFSF18 BCL6 SOCS5 SMAD7	1.68e-05	22	148	4	GO:0045623
GeneOntologyBiologicalProcess	negative regulation of CD4-positive, alpha-beta T cell differentiation	TNFSF18 BCL6 SOCS5 SMAD7	3.37e-05	26	148	4	GO:0043371
GeneOntologyBiologicalProcess	regulation of flagellated sperm motility	CLXN EPPIN PGAM4 CFAP69	4.56e-05	28	148	4	GO:1901317
GeneOntologyBiologicalProcess	regulation of T-helper cell differentiation	TNFSF18 BCL6 NLRP3 SOCS5 SMAD7	5.51e-05	57	148	5	GO:0045622
GeneOntologyBiologicalProcess	regulation of alpha-beta T cell differentiation	TNFSF18 BCL6 NLRP3 SOCS5 SMAD7 NCKAP1L	5.62e-05	93	148	6	GO:0046637
GeneOntologyBiologicalProcess	DNA damage response	GCNA PLK2 SETMAR SETX HIPK1 ZGRF1 POLE RAD21L1 BCL6 MCM10 RFC4 FAAP100 TRIP12 PARP4 ALKBH8 FBH1 RECQL4 USP3 RAD21	5.82e-05	959	148	19	GO:0006974
GeneOntologyBiologicalProcess	negative regulation of alpha-beta T cell differentiation	TNFSF18 BCL6 SOCS5 SMAD7	6.89e-05	31	148	4	GO:0046639
GeneOntologyBiologicalProcess	regulation of CD4-positive, alpha-beta T cell activation	TNFSF18 BCL6 NLRP3 SOCS5 SMAD7 NCKAP1L	8.44e-05	100	148	6	GO:2000514
GeneOntologyBiologicalProcess	T cell activation involved in immune response	TNFSF18 HLA-DMB BCL6 NLRP3 SOCS5 SMAD7 NCKAP1L	9.77e-05	148	148	7	GO:0002286
GeneOntologyBiologicalProcess	regulation of T-helper 2 cell differentiation	BCL6 NLRP3 SOCS5	1.24e-04	14	148	3	GO:0045628
GeneOntologyBiologicalProcess	regulation of cilium movement involved in cell motility	CLXN EPPIN PGAM4 CFAP69	1.40e-04	37	148	4	GO:0060295
GeneOntologyBiologicalProcess	regulation of cilium-dependent cell motility	CLXN EPPIN PGAM4 CFAP69	1.40e-04	37	148	4	GO:1902019
GeneOntologyBiologicalProcess	muscle filament sliding	MYH2 MYH4 MYH8	1.55e-04	15	148	3	GO:0030049
GeneOntologyBiologicalProcess	negative regulation of CD4-positive, alpha-beta T cell activation	TNFSF18 BCL6 SOCS5 SMAD7	1.90e-04	40	148	4	GO:2000515
GeneOntologyBiologicalProcess	CD4-positive, alpha-beta T cell differentiation	TNFSF18 BCL6 NLRP3 SOCS5 SMAD7 NCKAP1L	2.20e-04	119	148	6	GO:0043367
GeneOntologyBiologicalProcess	DNA repair	GCNA SETMAR SETX ZGRF1 POLE RAD21L1 RFC4 FAAP100 TRIP12 PARP4 FBH1 RECQL4 USP3 RAD21	2.43e-04	648	148	14	GO:0006281
GeneOntologyBiologicalProcess	DNA duplex unwinding	SETX ZGRF1 RFC4 FBH1 RECQL4	2.46e-04	78	148	5	GO:0032508
GeneOntologyBiologicalProcess	actin-myosin filament sliding	MYH2 MYH4 MYH8	2.73e-04	18	148	3	GO:0033275
GeneOntologyBiologicalProcess	DNA-templated DNA replication	SETMAR POLE BCL6 MCM10 RFC4 FBH1 RECQL4	3.05e-04	178	148	7	GO:0006261
GeneOntologyBiologicalProcess	pyramidal neuron differentiation	BCL6 OGDH UNC5D	3.22e-04	19	148	3	GO:0021859
GeneOntologyBiologicalProcess	DNA geometric change	SETX ZGRF1 RFC4 FBH1 RECQL4	3.88e-04	86	148	5	GO:0032392
GeneOntologyBiologicalProcess	regulation of cilium movement	CLXN EPPIN PGAM4 CFAP69	4.20e-04	49	148	4	GO:0003352
GeneOntologyBiologicalProcess	chromosome organization	KNTC1 MAP9 SETMAR SETX VPS4A ZGRF1 RAD21L1 RFC4 TEP1 NCAPH PARP4 FBH1 RECQL4 RAD21	4.31e-04	686	148	14	GO:0051276
GeneOntologyBiologicalProcess	T-helper 2 cell differentiation	BCL6 NLRP3 SOCS5	4.38e-04	21	148	3	GO:0045064
GeneOntologyBiologicalProcess	lymphocyte activation involved in immune response	TNFSF18 HLA-DMB IRF8 BCL6 NLRP3 SOCS5 SMAD7 NCKAP1L	4.69e-04	251	148	8	GO:0002285
GeneOntologyBiologicalProcess	lymphocyte differentiation	CACNB4 TNFSF18 IRF8 AQP8 BCL6 NLRP3 SOCS5 PKNOX1 RNF41 PREX1 SMAD7 NCKAP1L	5.07e-04	537	148	12	GO:0030098
GeneOntologyBiologicalProcess	negative regulation of alpha-beta T cell activation	TNFSF18 BCL6 SOCS5 SMAD7	5.27e-04	52	148	4	GO:0046636
GeneOntologyBiologicalProcess	T-helper cell differentiation	TNFSF18 BCL6 NLRP3 SOCS5 SMAD7	5.29e-04	92	148	5	GO:0042093
GeneOntologyBiologicalProcess	regulation of alpha-beta T cell activation	TNFSF18 BCL6 NLRP3 SOCS5 SMAD7 NCKAP1L	5.46e-04	141	148	6	GO:0046634
GeneOntologyBiologicalProcess	CD4-positive, alpha-beta T cell differentiation involved in immune response	TNFSF18 BCL6 NLRP3 SOCS5 SMAD7	5.84e-04	94	148	5	GO:0002294
GeneOntologyBiologicalProcess	DNA conformation change	SETX ZGRF1 RFC4 FBH1 RECQL4	5.84e-04	94	148	5	GO:0071103
GeneOntologyCellularComponent	muscle myosin complex	MYH1 MYH2 MYH4 MYH8	4.22e-06	16	149	4	GO:0005859
GeneOntologyCellularComponent	myosin filament	MYH1 MYH2 MYH4 MYH8	2.79e-05	25	149	4	GO:0032982
GeneOntologyCellularComponent	myosin II complex	MYH1 MYH2 MYH4 MYH8	4.44e-05	28	149	4	GO:0016460
MousePheno	abnormal germ cell physiology	PRAMEF33 SETX BTBD18 RAD21L1 YTHDC2 BCL6 PRAMEF1 FAAP100 PRAMEF14 ZDHHC19 EIF4G3	2.17e-05	267	122	11	MP:0020363
MousePheno	increased male germ cell apoptosis	PRAMEF33 SETX BTBD18 YTHDC2 BCL6 PRAMEF1 PRAMEF14 ZDHHC19 EIF4G3	4.09e-05	189	122	9	MP:0014052
MousePheno	abnormal male germ cell apoptosis	PRAMEF33 SETX BTBD18 RAD21L1 YTHDC2 BCL6 PRAMEF1 PRAMEF14 ZDHHC19 EIF4G3	4.10e-05	236	122	10	MP:0008280
MousePheno	abnormal male germ cell physiology	PRAMEF33 SETX BTBD18 RAD21L1 YTHDC2 BCL6 PRAMEF1 PRAMEF14 ZDHHC19 EIF4G3	5.44e-05	244	122	10	MP:0020362
Domain	P-loop_NTPase	DNHD1 MYH1 MYH2 MYH4 CACNB1 CACNB4 MYH8 SETX DHX37 VPS4A ZGRF1 RNF213 YTHDC2 RFC4 TEP1 NLRP3 ATL1 FBH1 MPP4 RECQL4 HELZ ABCG5	9.18e-07	848	148	22	IPR027417
Domain	Myosin_N	MYH1 MYH2 MYH4 MYH8	4.83e-06	15	148	4	PF02736
Domain	Myosin_N	MYH1 MYH2 MYH4 MYH8	4.83e-06	15	148	4	IPR004009
Domain	Myosin_tail_1	MYH1 MYH2 MYH4 MYH8	1.06e-05	18	148	4	PF01576
Domain	Myosin_tail	MYH1 MYH2 MYH4 MYH8	1.06e-05	18	148	4	IPR002928
Domain	Myosin-like_IQ_dom	MYH1 MYH2 MYH4 MYH8	1.34e-05	19	148	4	IPR027401
Domain	-	MYH1 MYH2 MYH4 MYH8	1.34e-05	19	148	4	4.10.270.10
Domain	-	DNHD1 CACNB1 CACNB4 SETX DHX37 VPS4A ZGRF1 RNF213 YTHDC2 RFC4 TEP1 ATL1 FBH1 MPP4 RECQL4 HELZ ABCG5	8.92e-05	746	148	17	3.40.50.300
Domain	Rad21/Rec8_C_eu	RAD21L1 RAD21	1.86e-04	3	148	2	IPR006909
Domain	Rad21_Rec8_N	RAD21L1 RAD21	1.86e-04	3	148	2	IPR006910
Domain	Rad21_Rec8_N	RAD21L1 RAD21	1.86e-04	3	148	2	PF04825
Domain	Rad21_Rec8	RAD21L1 RAD21	1.86e-04	3	148	2	PF04824
Domain	Rad21/Rec8_C	RAD21L1 RAD21	1.86e-04	3	148	2	IPR023093
Domain	-	RAD21L1 RAD21	1.86e-04	3	148	2	1.10.10.580
Domain	Myosin_head_motor_dom	MYH1 MYH2 MYH4 MYH8	2.27e-04	38	148	4	IPR001609
Domain	MYOSIN_MOTOR	MYH1 MYH2 MYH4 MYH8	2.27e-04	38	148	4	PS51456
Domain	Myosin_head	MYH1 MYH2 MYH4 MYH8	2.27e-04	38	148	4	PF00063
Domain	MYSc	MYH1 MYH2 MYH4 MYH8	2.27e-04	38	148	4	SM00242
Domain	VDCC_L_bsu	CACNB1 CACNB4	3.70e-04	4	148	2	IPR000584
Domain	VGCC_beta4Aa_N	CACNB1 CACNB4	3.70e-04	4	148	2	PF12052
Pathway	KEGG_VIRAL_MYOCARDITIS	MYH1 MYH2 MYH4 MYH8 HLA-DMB EIF4G3	1.25e-05	70	104	6	M12294
Pubmed	Developmental pattern of mouse skeletal myosin heavy chain gene transcripts in vivo and in vitro.	MYH1 MYH2 MYH4 MYH8	1.70e-09	5	151	4	3829126
Pubmed	Myosin heavy chain isoforms of the murine masseter muscle during pre- and post-natal development.	MYH1 MYH2 MYH4 MYH8	1.70e-09	5	151	4	12919077
Pubmed	Sequential accumulation of mRNAs encoding different myosin heavy chain isoforms during skeletal muscle development in vivo detected with a recombinant plasmid identified as coding for an adult fast myosin heavy chain from mouse skeletal muscle.	MYH1 MYH2 MYH4 MYH8	1.70e-09	5	151	4	6196357
Pubmed	Distinct myogenic programs of embryonic and fetal mouse muscle cells: expression of the perinatal myosin heavy chain isoform in vitro.	MYH1 MYH2 MYH4 MYH8	5.09e-09	6	151	4	1728586
Pubmed	Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.	MYH1 MYH2 MYH4 MYH8	5.09e-09	6	151	4	10077619
Pubmed	Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development.	MYH1 MYH2 MYH4 MYH8	5.09e-09	6	151	4	10588881
Pubmed	A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.	MYH1 MYH2 MYH4 MYH8	1.18e-08	7	151	4	35210422
Pubmed	Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.	MYH1 MYH2 MYH4 MYH8	1.18e-08	7	151	4	16819597
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CFAP47 MYH1 MYH4 ILF2 SETX NEXMIF RNF213 TRIP12 TMEM132B NDUFS2 FREM2 PARP4 DST FAM120C RECQL4 ARHGAP20 FBXO34	2.49e-08	736	151	17	29676528
Pubmed	Transition of myosin heavy chain isoforms in human laryngeal abductors following denervation.	MYH1 MYH2 MYH4	8.02e-08	3	151	3	26059207
Pubmed	Modulation of contractile protein gene expression in fetal murine crural muscles: emergence of muscle diversity.	MYH1 MYH2 MYH4 MYH8	1.10e-07	11	151	4	8136524
Pubmed	Contractile protein gene expression in primary myotubes of embryonic mouse hindlimb muscles.	MYH1 MYH2 MYH4 MYH8	2.37e-07	13	151	4	8404542
Pubmed	Evaluation of embryonic and perinatal myosin gene mutations and the etiology of congenital idiopathic clubfoot.	MYH1 MYH2 MYH8	3.20e-07	4	151	3	20357587
Pubmed	Three linked myosin heavy chain genes clustered within 370 kb of each other show independent transcriptional and post-transcriptional regulation during differentiation of a mouse muscle cell line.	MYH1 MYH4 MYH8	3.20e-07	4	151	3	1985022
Pubmed	Smooth muscle myosin light chain kinase expression in cardiac and skeletal muscle.	MYH1 MYH2 MYH4	3.20e-07	4	151	3	11029314
Pubmed	Modulation of skeletal muscle fiber type by mitogen-activated protein kinase signaling.	MYH1 MYH2 MYH4	3.20e-07	4	151	3	18417546
Pubmed	Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity.	MYH1 MYH2 MYH4	3.20e-07	4	151	3	10388558
Pubmed	A human YAC transgene rescues craniofacial and neural tube development in PDGFRalpha knockout mice and uncovers a role for PDGFRalpha in prenatal lung growth.	MYH1 MYH2 MYH4	3.20e-07	4	151	3	11023856
Pubmed	Defective excitation-contraction coupling is partially responsible for impaired contractility in hindlimb muscles of Stac3 knockout mice.	MYH1 MYH2 MYH4 MYH8	3.30e-07	14	151	4	27184118
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	TNPO1 DHX37 MCM10 AP2B1 PHF3 HELZ EIF4G3 ZNF512 MAP2K1 RAD21 NCKAP1L	7.25e-07	370	151	11	22922362
Pubmed	Detection of Gene and Protein Expression in Mouse Embryos and Tissue Sections.	MYH1 MYH2 MYH4	7.97e-07	5	151	3	30737693
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PLEKHB2 COG2 PLK2 SETMAR CNST HIPK1 TRIP12 RYR3 STAB1 POLR3B DST FBH1 AP2B1 NETO1 PKNOX1 EIF4G3 PREX1 TARS1 RSBN1L ALPL	8.19e-07	1285	151	20	35914814
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TNPO1 ILF2 DHX37 POLE YTHDC2 TRIP12 WDR43 DST AP2B1 PHF3 HELZ EIF4G3 ZNF512 RAD21	1.10e-06	653	151	14	22586326
Pubmed	A hypoplastic model of skeletal muscle development displaying reduced foetal myoblast cell numbers, increased oxidative myofibres and improved specific tension capacity.	MYH1 MYH2 MYH4	1.59e-06	6	151	3	20417199
Pubmed	A role for Insulin-like growth factor 2 in specification of the fast skeletal muscle fibre.	MYH1 MYH2 MYH4	1.59e-06	6	151	3	17559643
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SPAM1 TES VPS4A BTBD18 RNF213 YTHDC2 RFC4 TEP1 YEATS2 ZNF469 MTUS1 CCNB3 FAM120C EHMT1 HELZ UNC5D RSBN1L ALPL	1.85e-06	1116	151	18	31753913
Pubmed	A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis.	MYH1 MYH2 MYH4 MYH8	2.35e-06	22	151	4	24301466
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	TNPO1 CPNE2 TES ILF2 DHX37 YTHDC2 RFC4 NCAPH TRIP12 NDUFS2 THOC5 WDR43 HARS2 DST AP2B1 PHF3 TARS1 RSBN1L RAD21	2.42e-06	1257	151	19	36526897
Pubmed	ANKK1 is found in myogenic precursors and muscle fibers subtypes with glycolytic metabolism.	MYH1 MYH2 MYH4	2.77e-06	7	151	3	29758057
Pubmed	Cell lineage- and expression-based inference of the roles of forkhead box transcription factor Foxc2 in craniofacial development.	MYH1 MYH2 MYH4	4.42e-06	8	151	3	33667029
Pubmed	A Tcf4-positive mesodermal population provides a prepattern for vertebrate limb muscle patterning.	MYH1 MYH2 MYH4	4.42e-06	8	151	3	14667415
Pubmed	Neuromuscular junction immaturity and muscle atrophy are hallmarks of the ColQ-deficient mouse, a model of congenital myasthenic syndrome with acetylcholinesterase deficiency.	MYH1 MYH2 MYH4	4.42e-06	8	151	3	26993635
Pubmed	Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene.	MYH1 MYH4 MYH8	4.42e-06	8	151	3	3864153
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	TNPO1 KNTC1 MYH2 COG2 VPS4A RNF213 YTHDC2 HMGCR RFC4 NCAPH OGDH NDUFS2 SMTN ARFGEF3 POLR3B DST AP2B1 COMMD9 ATP1B1 ALPL	4.59e-06	1440	151	20	30833792
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	ILF2 DHX37 POLE YTHDC2 MCM10 RFC4 OGDH TRIP12 WDR43 POLR3B PHF3 EIF4G3 ZNF512 RAD21	6.21e-06	759	151	14	35915203
Pubmed	GASP-2 overexpressing mice exhibit a hypermuscular phenotype with contrasting molecular effects compared to GASP-1 transgenics.	MYH1 MYH2 MYH4	6.61e-06	9	151	3	31960486
Pubmed	During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation.	MYH1 MYH4 MYH8	9.41e-06	10	151	3	19506036
Pubmed	Acceleration of somitic myogenesis in embryos of myogenin promoter-MRF4 transgenic mice.	MYH1 MYH2 MYH8	9.41e-06	10	151	3	8950513
Pubmed	Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development.	MYH1 MYH2 MYH4 MYH8	1.27e-05	33	151	4	32094117
Pubmed	Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle.	MYH1 MYH2 MYH4	1.29e-05	11	151	3	18310078
Pubmed	Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers.	MYH1 MYH2 MYH4	1.29e-05	11	151	3	16024798
Pubmed	Extracellular matrix protein composition dynamically changes during murine forelimb development.	MYH1 MYH2 MYH4	1.29e-05	11	151	3	38303699
Pubmed	The histone code reader Spin1 controls skeletal muscle development.	MYH1 MYH2 MYH4	1.29e-05	11	151	3	29168801
Pubmed	Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.	CFAP47 PRAMEF33 VPS4A PRAMEF1 TRIP12 MTUS1 MPP4 PRAMEF14 EHMT1	1.38e-05	326	151	9	17015433
Pubmed	CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.	TNPO1 ILF2 RFC4 OGDH PARP4 AP2B1 RNF41	1.57e-05	182	151	7	31067453
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	DNHD1 RNF213 ZNF469 DST HELZ SSH2 MUC5AC	1.87e-05	187	151	7	26460568
Pubmed	Myosin heavy chains IIa and IId are functionally distinct in the mouse.	MYH1 MYH2	1.87e-05	2	151	2	9585413
Pubmed	Vault poly(ADP-ribose) polymerase is associated with mammalian telomerase and is dispensable for telomerase function and vault structure in vivo.	TEP1 PARP4	1.87e-05	2	151	2	15169895
Pubmed	Chromosomal mapping of the PFTAIRE gene, Pftk1, a cdc2-related kinase expressed predominantly in the mouse nervous system.	DPP6 CDK14	1.87e-05	2	151	2	9205131
Pubmed	Analysis of mouse conceptuses with uniparental duplication/deficiency for distal chromosome 12: comparison with chromosome 12 uniparental disomy and implications for genomic imprinting.	MYH1 MYH2	1.87e-05	2	151	2	16575183
Pubmed	Growth and muscle defects in mice lacking adult myosin heavy chain genes.	MYH1 MYH4	1.87e-05	2	151	2	9382868
Pubmed	Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains.	MYH1 MYH4	1.87e-05	2	151	2	11150240
Pubmed	Myosin heavy chain composition of the human genioglossus muscle.	MYH1 MYH2	1.87e-05	2	151	2	22337492
Pubmed	BCL6 attenuates hyperoxia-induced lung injury by inhibiting NLRP3-mediated inflammation in fetal mouse.	BCL6 NLRP3	1.87e-05	2	151	2	38419581
Pubmed	Interleukin-enhanced binding factor 2 interacts with NLRP3 to inhibit the NLRP3 inflammasome activation.	ILF2 NLRP3	1.87e-05	2	151	2	29655789
Pubmed	Different pathways regulate expression of the skeletal myosin heavy chain genes.	MYH1 MYH2	1.87e-05	2	151	2	11551968
Pubmed	Five skeletal myosin heavy chain genes are organized as a multigene complex in the human genome.	MYH4 MYH8	1.87e-05	2	151	2	8518795
Pubmed	Type IIx myosin heavy chain transcripts are expressed in type IIb fibers of human skeletal muscle.	MYH1 MYH2	1.87e-05	2	151	2	7545970
Pubmed	Structures of the murine genes for the beta1- and beta4-subunits of the voltage-dependent calcium channel.	CACNB1 CACNB4	1.87e-05	2	151	2	14500989
Pubmed	BCL6 attenuates renal inflammation via negative regulation of NLRP3 transcription.	BCL6 NLRP3	1.87e-05	2	151	2	29072703
Pubmed	Increased susceptibility of vault poly(ADP-ribose) polymerase-deficient mice to carcinogen-induced tumorigenesis.	TEP1 PARP4	1.87e-05	2	151	2	16204055
Pubmed	Temporal spatial expression and function of non-muscle myosin II isoforms IIA and IIB in scar remodeling.	MYH2 MYH4	1.87e-05	2	151	2	21102503
Pubmed	Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice.	MYH1 MYH4	1.87e-05	2	151	2	11744674
Pubmed	The inhibition of differentiation caused by TGFbeta in fetal myoblasts is dependent upon selective expression of PKCtheta: a possible molecular basis for myoblast diversification during limb histogenesis.	MYH1 MYH2 MYH8	2.22e-05	13	151	3	8948582
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	CACNB1 CACNB4 RYR3 ATP2A3	2.25e-05	38	151	4	30786075
Pubmed	Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease.	MYH1 MYH2 MYH4 MYH8	2.50e-05	39	151	4	38690566
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	ILF2 SETX DHX37 VPS4A POLE MCM10 RFC4 NCAPH TRIP12 SMTN ACSL1 POLR3B DST AP2B1 RECQL4 ZNF512 USP3 TARS1	2.53e-05	1353	151	18	29467282
Pubmed	Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCα and TSC2-mTOR downregulation.	MYH1 MYH2 MYH4	2.82e-05	14	151	3	33742095
Pubmed	Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathy.	MYH1 MYH2 MYH4	2.82e-05	14	151	3	24938781
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	COL6A2 SETX DHX37 POLE YTHDC2 FREM2 PARP4 DST RECQL4 HELZ RSBN1L CNOT4	2.90e-05	650	151	12	38777146
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	COL6A2 ILF2 SETX POLE MCM10 FAAP100 SMTN PHF3 RECQL4 USP3	3.11e-05	453	151	10	29656893
Pubmed	Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.	NCAPH TRIP12 HELZ RAD21	3.36e-05	42	151	4	7584044
Pubmed	Six homeoproteins and a Iinc-RNA at the fast MYH locus lock fast myofiber terminal phenotype.	MYH1 MYH2 MYH4	3.51e-05	15	151	3	24852826
Pubmed	MusTRD can regulate postnatal fiber-specific expression.	MYH1 MYH2 MYH4	4.31e-05	16	151	3	16494860
Pubmed	A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance.	MYH1 MYH2 MYH4	4.31e-05	16	151	3	19922871
Pubmed	HOXA5 plays tissue-specific roles in the developing respiratory system.	MYH1 MYH2 MYH4 MYH8	4.83e-05	46	151	4	28827394
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	TNPO1 SETX POLE YTHDC2 RFC4 NCAPH TRIP12 STAB1 PARP4 FAM120C RAD21	5.11e-05	582	151	11	20467437
Pubmed	IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism.	MYH1 MYH2 MYH4	5.22e-05	17	151	3	22351927
Pubmed	Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H.	MYH2 MYH4 MYH8	5.22e-05	17	151	3	16124007
Pubmed	Simultaneous loss of skeletal muscle myosin heavy chain IIx and IIb causes severe skeletal muscle hypoplasia in postnatal mice.	MYH1 MYH4	5.60e-05	3	151	2	36515178
Pubmed	RecQL4 is required for the association of Mcm10 and Ctf4 with replication origins in human cells.	MCM10 RECQL4	5.60e-05	3	151	2	25602958
Pubmed	Binding of ADAM28 to P-selectin glycoprotein ligand-1 enhances P-selectin-mediated leukocyte adhesion to endothelial cells.	SELP ADAM28	5.60e-05	3	151	2	17597069
Pubmed	Expression profiles of vault components MVP, TEP1 and vPARP and their correlation to other multidrug resistance proteins in ovarian cancer.	TEP1 PARP4	5.60e-05	3	151	2	23739867
Pubmed	Molecular determinants of force production in human skeletal muscle fibers: effects of myosin isoform expression and cross-sectional area.	MYH1 MYH2	5.60e-05	3	151	2	25567808
Pubmed	PU.1 and IRF8 Modulate Activation of NLRP3 Inflammasome via Regulating Its Expression in Human Macrophages.	IRF8 NLRP3	5.60e-05	3	151	2	33897697
Pubmed	ZEB1 imposes a temporary stage-dependent inhibition of muscle gene expression and differentiation via CtBP-mediated transcriptional repression.	MYH2 MYH4	5.60e-05	3	151	2	23339872
Pubmed	The myosin alkali light chain proteins and their genes.	MYH2 MYH4	5.60e-05	3	151	2	3904738
Pubmed	Inflammatory mediators ATP and S100A12 activate the NLRP3 inflammasome to induce MUC5AC production in airway epithelial cells.	NLRP3 MUC5AC	5.60e-05	3	151	2	29906464
Pubmed	The expression of myosin heavy chain (MHC) genes in human skeletal muscle is related to metabolic characteristics involved in the pathogenesis of type 2 diabetes.	MYH1 MYH2	5.60e-05	3	151	2	21470888
Pubmed	Regional expression and subcellular localization of the voltage-gated calcium channel β subunits in the developing mouse brain.	CACNB1 CACNB4	5.60e-05	3	151	2	22737983
Pubmed	MVP Expression Facilitates Tumor Cell Proliferation and Migration Supporting the Metastasis of Colorectal Cancer Cells.	TEP1 PARP4	5.60e-05	3	151	2	34829999
Pubmed	Germ cell-intrinsic requirement for the homeodomain transcription factor PKnox1/Prep1 in adult spermatogenesis.	PKNOX1 ALPL	5.60e-05	3	151	2	29293683
Pubmed	Structural and developmental analysis of two linked myosin heavy chain genes.	MYH1 MYH2	5.60e-05	3	151	2	1371481
Pubmed	The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis.	RECQL4 ALPL	5.60e-05	3	151	2	24960165
Pubmed	Maximum velocity of shortening in relation to myosin isoform composition in single fibres from human skeletal muscles.	MYH2 MYH4	5.60e-05	3	151	2	8145163
Pubmed	T follicular helper cells restricted by IRF8 contribute to T cell-mediated inflammation.	IRF8 BCL6	5.60e-05	3	151	2	30241692
Pubmed	IRF8 Regulates Gram-Negative Bacteria-Mediated NLRP3 Inflammasome Activation and Cell Death.	IRF8 NLRP3	5.60e-05	3	151	2	32205422
Pubmed	Specific isomyosin proportions in hyperexcitable and physiologically denervated mouse muscle.	MYH2 MYH4	5.60e-05	3	151	2	15013776
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KNTC1 MYH1 MYH2 MAP9 MYH4 MYH8 NCAPH OGDH TRIP12 DST AP2B1 EFCAB12 PGAM4 EIF4G3 CFAP69 ATP2A3 PREX1 RBBP9	5.76e-05	1442	151	18	35575683
Pubmed	Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis.	MYH1 MYH2 MYH4	6.24e-05	18	151	3	25753484
Interaction	RSPH6A interactions	MYH1 MYH2 MYH4 MYH8 ATP2A3	4.38e-06	34	146	5	int:RSPH6A
Interaction	ABTB2 interactions	MYH1 MYH2 MYH4 MYH8 NLRP3 SMTN HELZ	8.83e-06	101	146	7	int:ABTB2
Interaction	PRKAG2 interactions	MYH1 MYH2 MYH4 MYH8 PHKG2 TARS1	9.86e-06	68	146	6	int:PRKAG2
Interaction	LZTR1 interactions	MYH1 MYH4 MYH8 VPS4A EHMT1 ATP2A3 GOLGA1	1.64e-05	111	146	7	int:LZTR1
Interaction	RNF123 interactions	CFAP47 MYH1 MYH4 ILF2 SETX NEXMIF RNF213 TRIP12 TMEM132B NDUFS2 FREM2 PARP4 DST FAM120C RECQL4 ARHGAP20 FBXO34 RAD21	2.96e-05	824	146	18	int:RNF123
GeneFamily	Myosin heavy chains	MYH1 MYH2 MYH4 MYH8	1.45e-06	15	106	4	1098
GeneFamily	UPF1 like RNA helicases	SETX ZGRF1 HELZ	3.12e-05	11	106	3	1169
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	CACNB1 CACNB4 MPP4	4.62e-04	26	106	3	904
Coexpression	HUMMERICH_BENIGN_SKIN_TUMOR_DN	MYH1 MYH2 MYH4 MYH8	4.77e-06	20	151	4	M1123
Coexpression	HUMMERICH_BENIGN_SKIN_TUMOR_DN	MYH1 MYH2 MYH4 MYH8	5.87e-06	21	151	4	MM1102
Coexpression	GSE2585_CD80_HIGH_VS_LOW_AIRE_KO_MTEC_DN	CLXN CDK14 NCAPH SMTN SNED1 ALKBH8 RECQL4 MAST3	2.11e-05	199	151	8	M6275
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPP6 ITPRID1 ADAM28 GSS ACSL1 MTUS1 NETO1 ATP1B1	2.00e-07	181	151	8	092a971661b0aa06c1cdf428dbfa7339a26fb678
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	DPP6 CACNB4 VEPH1 ARFGEF3 FREM2 MTUS1 MAPK10 ALPL	3.13e-07	192	151	8	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNB1 CACNB4 VEPH1 ARFGEF3 FREM2 MTUS1 MAPK10 ALPL	3.13e-07	192	151	8	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DPP6 CACNB4 VEPH1 ARFGEF3 FREM2 MTUS1 MAPK10 ALPL	3.39e-07	194	151	8	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HLA-DMB IRF8 HEMGN MCM10 NCAPH ADAM28 NLRP3 RECQL4	3.67e-07	196	151	8	53d1f9e9f009d1417a19ca6f9a83ecdf7776ef88
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DPP6 CACNB4 VEPH1 ARFGEF3 FREM2 MTUS1 MAPK10 ALPL	3.96e-07	198	151	8	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DPP6 CACNB4 VEPH1 ARFGEF3 FREM2 MTUS1 MAPK10 ALPL	3.96e-07	198	151	8	2e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCell	E18.5-Immune-Immune_Myeloid-DC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP47 HLA-DMB IRF8 TEP1 NLRP3 STK10 NCKAP1L	1.27e-06	160	151	7	9f1fec2cf565193c73cc3c8a4f0476e57478e3b8
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP47 HLA-DMB IRF8 TEP1 NLRP3 STK10 NCKAP1L	1.38e-06	162	151	7	388670cf3acef17df971c0d8ae3ce14398945192
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP47 HLA-DMB IRF8 TEP1 NLRP3 STK10 NCKAP1L	1.38e-06	162	151	7	9333d923225df7bfdf6b3a4c32816751315aec50
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Microglia/Mac\|Myeloid_cells / Location, Cell class and cell subclass	GCNA DNHD1 KNTC1 PLPP7 ALKBH8 ZDHHC19 MUC5AC	1.82e-06	169	151	7	dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 ZGRF1 POLE RAD21L1 MCM10 RFC4 NCAPH	1.82e-06	169	151	7	121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell	COVID-19-kidney-Bcells\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TDRD15 NEXMIF IRF8 ADAM28 MGAT5 NETO1 ATP2A3	1.97e-06	171	151	7	8e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	HLA-DMB IRF8 CDK14 ADAM28 MGAT5 NETO1 ZDHHC19	1.97e-06	171	151	7	c3e3ea09c73050372314a89b282e36ba5f339d73
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 MCM10 RFC4 ZSCAN29 EFCAB12 RECQL4 MAP2K1	2.13e-06	173	151	7	9f892d756d05e573af018db64edb130ff187ad47
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4\|Striatum / BrainAtlas - Mouse McCarroll V32	ILF2 POLE MCM10 RFC4 NCAPH RECQL4 RAD21	2.39e-06	176	151	7	d70fdc7bc48719776ed1e7c01118385e3a21623f
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_1\|Striatum / BrainAtlas - Mouse McCarroll V32	ILF2 POLE MCM10 RFC4 NCAPH RECQL4 RAD21	2.39e-06	176	151	7	a84361308e5e96f3a30246cd29e109c321ee65bf
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	CACNB4 VEPH1 ARFGEF3 FREM2 MTUS1 MAPK10 ALPL	2.77e-06	180	151	7	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B-B\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IRF8 CDK14 ADAM28 MGAT5 NETO1 SSH2 ATP2A3	2.88e-06	181	151	7	8d8cc4dae2c8bd5f4b1c159f2a52edc4c9449c86
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TES BCL6 ACSL1 ZDHHC19 SSH2 ALPL NCKAP1L	2.98e-06	182	151	7	dc32f8f6a3b13918eb8e93c018f5823d86344080
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 RYR3 ARFGEF3 FREM2 OTOGL PCDH15 UNC5D	3.21e-06	184	151	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC37A1 HLA-DMB PPFIBP2 IRF8 CDK14 ADAM28 NETO1	3.21e-06	184	151	7	d18e94839a62fca536ae1630c154e5d0aafc44c5
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 RYR3 ARFGEF3 FREM2 OTOGL PCDH15 UNC5D	3.21e-06	184	151	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 RYR3 ARFGEF3 FREM2 OTOGL PCDH15 UNC5D	3.21e-06	184	151	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COPD-Lymphoid-B\|COPD / Disease state, Lineage and Cell class	PPFIBP2 IRF8 ADAM28 SNED1 MGAT5 SSH2 ATP2A3	3.32e-06	185	151	7	925e79c35c381dd44ec5fb921dca09ce43140135
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b-Inhibitory_Gad1Gad2_Id2.Bcl11b_(Interneuron,_Neurogliaform2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MYH1 MYH8 RAD21L1 ADAM28 OTOGL	3.50e-06	68	151	5	cfd75c373e10b3761666ccd445ba74755efeb95f
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MYH1 MYH8 RAD21L1 ADAM28 OTOGL	3.50e-06	68	151	5	c25fb921dc83eecdc337353894829ae6b5192353
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b-Inhibitory_Gad1Gad2_Id2.Bcl11b_(Interneuron,_Neurogliaform2)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MYH1 MYH8 RAD21L1 ADAM28 OTOGL	3.50e-06	68	151	5	712f5f4d3a1e0c0db1a340332876206b93bdac31
ToppCell	Control-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	HLA-DMB PPFIBP2 IRF8 CDK14 ADAM28 SNED1 EHMT1	3.57e-06	187	151	7	4e64be635f445276e71f2937f33f041c3a4204ab
ToppCell	IPF-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	HLA-DMB PPFIBP2 IRF8 CDK14 ADAM28 SNED1 MGAT5	3.57e-06	187	151	7	af1327559f7e01bec070881cae52834917c3da65
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC37A1 HLA-DMB IRF8 CDK14 ADAM28 MGAT5 NETO1	3.83e-06	189	151	7	886dceacf96e2b6750c146a381da0bf96a2bb15b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC37A1 HLA-DMB IRF8 CDK14 ADAM28 MGAT5 NETO1	3.83e-06	189	151	7	5f1f4321939877374a8ee13de93f2d1390af8e2e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC37A1 HLA-DMB IRF8 CDK14 ADAM28 MGAT5 NETO1	3.96e-06	190	151	7	60bb6aaea9691d07295f61c14d1650f5041a0f9c
ToppCell	COPD-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	HLA-DMB PPFIBP2 IRF8 CDK14 ADAM28 SNED1 MGAT5	3.96e-06	190	151	7	1e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCell	COVID-19-Epithelial_cells-Airway_goblet\|COVID-19 / group, cell type (main and fine annotations)	NEXMIF ITPRID1 ADAM28 ARFGEF3 MTUS1 ATP1B1 MUC5AC	3.96e-06	190	151	7	51ca9ef4df3220487152fcf684147730637c7cc1
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DPP6 CACNB4 VEPH1 ARFGEF3 FREM2 MTUS1 MAPK10	4.10e-06	191	151	7	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	VEPH1 ARFGEF3 FREM2 MTUS1 ATP1B1 MAPK10 ALPL	4.10e-06	191	151	7	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNB4 VEPH1 ARFGEF3 FREM2 MTUS1 MAPK10 ALPL	4.39e-06	193	151	7	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	CACNB4 VEPH1 ARFGEF3 FREM2 MTUS1 MAPK10 ALPL	4.39e-06	193	151	7	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNB4 VEPH1 ARFGEF3 FREM2 MTUS1 MAPK10 ALPL	4.39e-06	193	151	7	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HLA-DMB ADAM28 NLRP3 STAB1 ACSL1 MAP2K1 PREX1	4.54e-06	194	151	7	663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IRF8 ADAM28 NLRP3 STAB1 ACSL1 PREX1 NCKAP1L	4.70e-06	195	151	7	91a3c439f10c03c5d51d904f512b6a08040edc76
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_cell-B_mature\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TDRD15 HLA-DMB IRF8 CDK14 ADAM28 MGAT5 NETO1	4.70e-06	195	151	7	3311a1bf4ed94820b45047d44fc14b14ac72e6fb
ToppCell	Children_(3_yrs)-Immune-monocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAM28 STAB1 ACSL1 STK10 SSH2 MAP2K1 PREX1	4.70e-06	195	151	7	81a28289eda1a8a1a31b7357106f64ac5000e172
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KNTC1 ZGRF1 POLE MCM10 RFC4 NCAPH RECQL4	4.70e-06	195	151	7	b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	IRF8 STAB1 ACSL1 STK10 MGAT5 PREX1 NCKAP1L	4.70e-06	195	151	7	247803cf58c6d9c561a52aa34e581188ddad197e
ToppCell	Adult-Immune-monocyte\|Adult / Lineage, Cell type, age group and donor	HLA-DMB ADAM28 NLRP3 STAB1 STK10 PREX1 NCKAP1L	4.86e-06	196	151	7	3ef193c5180de3137daf886492e74fc574bc9767
ToppCell	Children_(3_yrs)-Immune-monocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAM28 NLRP3 STAB1 STK10 MAP2K1 PREX1 NCKAP1L	4.86e-06	196	151	7	cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCell	Fetal_29-31_weeks-Immune-monocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAM28 NLRP3 STAB1 ACSL1 STK10 PREX1 NCKAP1L	5.02e-06	197	151	7	48a8169a4d33c6a68d66bcd936861c75cb4b60ef
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|lung / Disease (COVID-19 only), tissue and cell type	RNF213 STAB1 ACSL1 STK10 SSH2 PREX1 NCKAP1L	5.02e-06	197	151	7	a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCell	distal-2-Hematologic-EREG+_Dendritic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HLA-DMB ADAM28 NLRP3 STAB1 ACSL1 PTPN7 MAP2K1	5.02e-06	197	151	7	6fcca7c071e35786b715adeb18be317d34315d7e
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VEPH1 HMGCR BCL6 ARFGEF3 FREM2 MTUS1 ALPL	5.02e-06	197	151	7	bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RNF213 STAB1 ACSL1 STK10 SSH2 PREX1 NCKAP1L	5.19e-06	198	151	7	ea34096bee852a7e996f097fa279381afa8f86ff
ToppCell	Immune-monocyte\|World / Lineage, Cell type, age group and donor	ADAM28 NLRP3 STAB1 STK10 MAP2K1 PREX1 NCKAP1L	5.19e-06	198	151	7	d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HLA-DMB IRF8 ADAM28 NLRP3 STAB1 PREX1 NCKAP1L	5.37e-06	199	151	7	04adf46975aa4194ea40c7480f8a517def5d929c
ToppCell	Transverse-(5)_Dendritic_cell-(51)_cDC1\|Transverse / shred on region, Cell_type, and subtype	HLA-DMB IRF8 PLPP7 BCL6 ZNF469 DST ARHGAP20	5.37e-06	199	151	7	52dd1c4cd372f8ee515307a9200e357bb2145888
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KNTC1 MYH1 ZGRF1 POLE MCM10 RFC4 RECQL4	5.37e-06	199	151	7	1d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNB4 VEPH1 HMGCR ARFGEF3 FREM2 MTUS1 ALPL	5.37e-06	199	151	7	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	Transverse-Dendritic_cell-cDC1\|Transverse / Region, Cell class and subclass	HLA-DMB IRF8 PLPP7 BCL6 ZNF469 DST ARHGAP20	5.37e-06	199	151	7	b68419939d206417158a703f60a374bf8ec5d5a1
ToppCell	PND07-28-samps-Mesenchymal-Mesenchymal_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MYH1 TMEM132B NLRP3 CCNB3 PCDH15 MAPK10	5.48e-06	130	151	6	6c6a8b77af08b30b424d4f5def37315d3c6e28b2
ToppCell	PND07-28-samps-Mesenchymal-Mesenchymal_fibroblast-mesenchymal_B\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MYH1 TMEM132B NLRP3 CCNB3 PCDH15 MAPK10	5.48e-06	130	151	6	0706092f6b466585b3b4808b3b982a122d66cfcf
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HLA-DMB IRF8 ADAM28 NLRP3 STAB1 PREX1 NCKAP1L	5.55e-06	200	151	7	ad52b38df5c71f28829b04cd0e6b97f0f9f7610a
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NLRP3 STAB1 ACSL1 STK10 MAP2K1 PREX1 NCKAP1L	5.55e-06	200	151	7	5432bdf495431cd26f6e4cd585100f3652588913
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HLA-DMB IRF8 NLRP3 STAB1 ACSL1 PREX1 NCKAP1L	5.55e-06	200	151	7	27f498bcd706d0751091662996795b5270e46f14
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAM28 NLRP3 STAB1 STK10 MAP2K1 PREX1 NCKAP1L	5.55e-06	200	151	7	b4277b6faa69f20974696c7c422311f5c89e3663
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH2 MYH8 POLE FREM2 OTOGL PCDH15	1.02e-05	145	151	6	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CES5A HLA-DMB IRF8 NCAPH ADAM28 NCKAP1L	1.50e-05	155	151	6	9f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 SPAM1 TNFSF18 IRF8 NLRP3 ABCG5	1.61e-05	157	151	6	7fdc0094dd5729990a91a30c1982a14c74650b52
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-microglial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 SPAM1 TNFSF18 IRF8 NLRP3 ABCG5	1.61e-05	157	151	6	c762b03e254c73222094725ca8ac1c8eb428bccb
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 SPAM1 TNFSF18 IRF8 NLRP3 ABCG5	1.61e-05	157	151	6	6b5b08bb5520fcf6f4c0560f7ed7645ec179806d
ToppCell	facs-GAT-Fat-18m-Lymphocytic-NK_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF8 HEMGN PTPN7 RECQL4 ATP1B1 ATP2A3	1.73e-05	159	151	6	796e63f6052189106359a4e01eae3e466bf1d593
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITPRID1 ADAM28 GSS ACSL1 MTUS1 ATP1B1	1.86e-05	161	151	6	c4970501c038ed36de447da70eabff020ad78713
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITPRID1 ADAM28 GSS ACSL1 MTUS1 ATP1B1	1.86e-05	161	151	6	41a89a3d99a9bd6039a3d881d1d9dcd18bc07f25
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYH2 POLE FREM2 OTOGL PCDH15 UNC5D	1.92e-05	162	151	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_B-Memory_B_cells\|GI_small-bowel / Manually curated celltypes from each tissue	HLA-DMB PPFIBP2 NEXMIF IRF8 CDK14 ADAM28	2.36e-05	168	151	6	8e025bb0541746e232b77ac0e31412ae71420c47
ToppCell	Control\|World / group, cell type (main and fine annotations)	VEPH1 ARFGEF3 FREM2 MAPK10 MUC5AC ALPL	2.36e-05	168	151	6	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_B\|GI_small-bowel / Manually curated celltypes from each tissue	HLA-DMB PPFIBP2 NEXMIF IRF8 CDK14 ADAM28	2.36e-05	168	151	6	5535c1b8b7fde7b59a1bc0580cebdfa963aa1c39
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 ZGRF1 POLE MCM10 NCAPH RECQL4	2.44e-05	169	151	6	0bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 ZGRF1 POLE MCM10 NCAPH RECQL4	2.44e-05	169	151	6	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Microglia/Mac\|metastatic_Lymph_Node / Location, Cell class and cell subclass	DNHD1 KNTC1 PLPP7 STAB1 ZDHHC19 MUC5AC	2.69e-05	172	151	6	f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Myeloid-cDC1\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-DMB IRF8 BCL6 ADAM28 TGM5 ARHGAP20	2.78e-05	173	151	6	d13ae4046a25ee0fb492ddedf44583a879a432e9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 SPAM1 IRF8 NCAPH NLRP3 NCKAP1L	2.87e-05	174	151	6	7b318796728001c17b4043d2b033330c7be40c78
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HLA-DMB IRF8 CDK14 ADAM28 NETO1 ARHGAP20	3.26e-05	178	151	6	5d41fede13c8e64b6fdaf2155f1eb72bcfc32fdb
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IRF8 MCM10 NCAPH NLRP3 PTPN7 ALPL	3.37e-05	179	151	6	9dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCell	PND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP47 MAP9 CLXN ZNF469 EFCAB12 PCDH15	3.48e-05	180	151	6	5c9d2d44d840cd4ec7d42d43446ba2b689e7ec43
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IRF8 ADAM28 MGAT5 NETO1 ATP2A3 NCKAP1L	3.48e-05	180	151	6	65c069585737302a69b9a01476f4eb8b50cb2bfd
ToppCell	PND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP47 MAP9 CLXN ZNF469 EFCAB12 PCDH15	3.48e-05	180	151	6	c60e74fbbd815a0251253a19dc520a254b2e1762
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SETX ZGRF1 STAB1 TINAGL1 NEK3 MTUS1	3.58e-05	181	151	6	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPP6 ADAM28 RYR3 PTPN7 MGAT5 DST	3.58e-05	181	151	6	5bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPP6 ADAM28 RYR3 PTPN7 MGAT5 DST	3.58e-05	181	151	6	8e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	CDK14 ARFGEF3 FREM2 MTUS1 ATP1B1 MAPK10	3.58e-05	181	151	6	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 ZGRF1 MCM10 NCAPH ATP1B1 ALPL	3.70e-05	182	151	6	3948422707d6d5e021bcd7158e2eb69143613f62
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 ZGRF1 MCM10 NCAPH ATP1B1 ALPL	3.70e-05	182	151	6	fe46819c153a81911864473badc794f243705f98
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	HLA-DMB PPFIBP2 IRF8 CDK14 ADAM28 NETO1	3.70e-05	182	151	6	ccd729388d997cc45071175cb0c3db6d0790eaf8
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNB4 VEPH1 FREM2 MTUS1 ATP1B1 MAPK10	3.81e-05	183	151	6	6847c1252d6bb105524f812658112517fd351eab
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITPRID1 ADAM28 ACSL1 MTUS1 ATP1B1 MUC5AC	3.81e-05	183	151	6	514b72a1ae55656934839800513385e19bc240e2
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5\|Striatum / BrainAtlas - Mouse McCarroll V32	KNTC1 ILF2 POLE MCM10 RFC4 NCAPH	3.81e-05	183	151	6	f20b0d71f857ac35868fd80531050ad8b6091716
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITPRID1 ADAM28 ACSL1 MTUS1 ATP1B1 MUC5AC	3.93e-05	184	151	6	49eccf72725593a8fb4a529e7985a5c413b3ca6a
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITPRID1 ADAM28 ACSL1 MTUS1 ATP1B1 MUC5AC	3.93e-05	184	151	6	41164109d9d7bb1c431220e2e85e08dc5f56856d
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	VEPH1 ARFGEF3 FREM2 MTUS1 MAPK10 ALPL	3.93e-05	184	151	6	369b82f793deab672204558ae4e112cfa5aa9ccc
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH1 MYH2 MYH4 MYH8	1.09e-07	10	143	4	DOID:0111269 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH1 MYH2 MYH4 MYH8	1.09e-07	10	143	4	DOID:0111602 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH1 MYH2 MYH4 MYH8	1.09e-07	10	143	4	DOID:0111596 (implicated_via_orthology)
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH1 MYH2 MYH4 MYH8	1.09e-07	10	143	4	DOID:0110454 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH1 MYH2 MYH4 MYH8	1.09e-07	10	143	4	DOID:0080719 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH1 MYH2 MYH4 MYH8	1.09e-07	10	143	4	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH1 MYH2 MYH4 MYH8	1.09e-07	10	143	4	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH1 MYH2 MYH4 MYH8	1.09e-07	10	143	4	DOID:0080326 (implicated_via_orthology)
Disease	distal myopathy (implicated_via_orthology)	MYH1 MYH2 MYH4 MYH8	2.54e-07	12	143	4	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH1 MYH2 MYH4 MYH8	2.54e-07	12	143	4	DOID:2106 (implicated_via_orthology)
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH1 MYH2 MYH4 MYH8	3.66e-07	13	143	4	DOID:397 (implicated_via_orthology)
Disease	distal arthrogryposis (implicated_via_orthology)	MYH1 MYH2 MYH4 MYH8	6.93e-07	15	143	4	DOID:0050646 (implicated_via_orthology)
Disease	myopathy (implicated_via_orthology)	MYH1 MYH2 MYH4 MYH8 HMGCR	3.61e-06	48	143	5	DOID:423 (implicated_via_orthology)
Disease	pancreatic adenocarcinoma (is_implicated_in)	MAPK10 MAP2K1 SMAD7	4.86e-05	15	143	3	DOID:4074 (is_implicated_in)
Disease	chemotherapy-induced alopecia	CACNB4 PCDH15	6.97e-05	3	143	2	EFO_0005400
Disease	cardiomyopathy (implicated_via_orthology)	MYH1 MYH2 MYH4 MYH8	3.99e-04	71	143	4	DOID:0050700 (implicated_via_orthology)
Disease	phosphate measurement	RYR3 ALPL	4.82e-04	7	143	2	EFO_0010968
Disease	dilated cardiomyopathy (implicated_via_orthology)	MYH1 MYH2 MYH4 MYH8	6.29e-04	80	143	4	DOID:12930 (implicated_via_orthology)
Disease	nucleus accumbens volume change measurement	ITPRID1 MAPK10	1.25e-03	11	143	2	EFO_0021493
Disease	ornithine measurement	DPP6 OGDH TINAGL1	1.28e-03	44	143	3	EFO_0009776
Disease	phosphocreatine measurement	MGAT5 ALPL	1.76e-03	13	143	2	EFO_0010521
Disease	T-cell surface glycoprotein CD3 epsilon chain measurement	SELP ATP1B1	1.76e-03	13	143	2	EFO_0802114
Disease	Idiopathic hypogonadotropic hypogonadism	POLR3B IL17RD	3.39e-03	18	143	2	C0342384
Disease	Malignant neoplasm of endometrium	POLE RAD21	3.39e-03	18	143	2	C0007103
Disease	Carcinoma in situ of endometrium	POLE RAD21	3.39e-03	18	143	2	C0346191
Disease	Hypercholesterolemia, Familial	HMGCR ABCG5	3.39e-03	18	143	2	C0020445
Disease	triglycerides to total lipids in medium VLDL percentage	TDRD15 HMGCR ABCG5	3.58e-03	63	143	3	EFO_0022335
Disease	cholesterol to total lipids in medium VLDL percentage	TDRD15 HMGCR ABCG5	3.58e-03	63	143	3	EFO_0022239
Disease	low density lipoprotein cholesterol measurement, physical activity	TDRD15 HMGCR OGDH	4.08e-03	66	143	3	EFO_0003940, EFO_0004611
Disease	coagulation factor V measurement	SELP ATP1B1	4.18e-03	20	143	2	EFO_0008087
Disease	Liver Cirrhosis, Experimental	COL6A2 TES IRF8 HMGCR ACSL1 STK10 MGAT5 INMT ABCG5 NCKAP1L	4.57e-03	774	143	10	C0023893

Protein segments in the cluster

Peptide	Gene	Start	Entry
EDCPRMGEHQPLKVF	PRAMEF33	136	A0A0G2JMD5
MEPAPGLVEQPKCLE	ADAT3	1	Q96EY9
MIFEDCGDVPSEPKE	ATP1B1	121	P05026
TVPLVSLCDGDMEKP	CPNE2	211	Q96FN4
MAVNSFVKDCEDPNP	AP2B1	86	P63010
IAASEKLAQCPPEMF	CACNB1	371	Q02641
KLAQCPPEMFDIILD	CACNB1	376	Q02641
RPAKDECDLPEMCNG	ADAM28	466	Q9UKQ2
EKCGLVDALLMPPNK	ALKBH8	66	Q96BT7
GAPMPCNLIKLVDVE	ACSL1	481	P33121
LNSCEDPVPGMLFFL	FBXO34	471	Q9NWN3
SACLGKEDVPFPLMA	CLDN25	186	C9JDP6
AMCEPEFGNDKAREP	AQP8	6	O94778
MCDLIEPQPAEKIGK	CDK14	1	O94921
PLPELRELDAMAECK	DNHD1	4366	Q96M86
LVAADKLAQCPPEMF	CACNB4	361	O00305
KLAQCPPEMFDVILD	CACNB4	366	O00305
PGDKIIFQMDKVCPI	EFCAB12	421	Q6NXP0
ALGFNPPDLDIMEKL	ATP2A3	806	Q93084
CPELLDFQDMIGEDK	CCNB3	546	Q8WWL7
PDAKELELMFGCQVE	MAP2K1	266	Q02750
KMTFCPGLVDLPKEN	RAD21L1	86	Q9H4I0
LKPLPACEFEMGGSE	NETO1	166	Q8TDF5
KMAFRPGVVDLPEEN	RAD21	86	O60216
GPFQIRIQDMKECPE	PTPN7	216	P35236
LEKIPGFQCLAKNMP	RBBP9	31	O75884
LVLNDVMCKPGPESD	IL17RD	586	Q8NFM7
PVCAIKNEEEMAPDG	MAP9	106	Q49MG5
NELFEVREKPGPEMA	GOLGA1	661	Q92805
IEQLGTPCPEFMKKL	MAPK10	276	P53779
DIINGAQEKCVLPPM	MGAT5	136	Q09328
LGFGADEPDICMQIP	ITPRID1	151	Q6ZRS4
DEPDICMQIPARFLG	ITPRID1	156	Q6ZRS4
PSPEAEMLKFNLECL	INMT	31	O95050
IDDECPLMVPAFDKS	MTUS1	346	Q9ULD2
PEIILGLPFCEAIDM	HIPK1	361	Q86Z02
PAMEKCLVFEDAPNG	PUDP	166	Q08623
TLPDKMPDLGDLEAC	DST	1931	Q03001
AGPLCLDEKEFQVPM	HMGCR	541	P04035
LPGETEKPCILELMD	FREM2	2191	Q5SZK8
FGMDLAACIELIEKP	MYH8	516	P13535
VVLCFGEEFPDMAPL	IRF8	346	Q02556
FGMDLAACIELIEKP	MYH2	516	Q9UKX2
CGFLLPMKEAPEILS	CES5A	346	Q6NT32
YAMEIGKKIPVPDQC	VEPH1	561	Q14D04
IPCMDAGLPFQKGDI	MPP4	261	Q96JB8
LMGPIECLKEFVTPD	NCKAP1L	936	P55160
VPPDTAPCEILKMFL	KNTC1	2191	P50748
FGMDLAACIELIEKP	MYH1	516	P12882
ANPMKPKDGSEEVCL	MCM10	356	Q7L590
PPEAPIFDEDKMQCV	MUC5AC	1211	P98088
PIKPMQFLGDEETVC	PGAM4	226	Q8N0Y7
KLGYDPVELDPEDMC	POLE	431	Q07864
CMLVFQPDLDVDLPD	PARP4	856	Q9UKK3
KMQLFEQPCPGEDPR	FAAP100	151	Q0VG06
MADFTGPCPLEIERI	HELZ	41	P42694
DVVPCPDEKPFMIQQ	IKZF5	276	Q9H5V7
PGYLAPEILKCSMDE	PHKG2	191	P15735
EDLAPKMCQEAAVPK	HEMGN	226	Q9BXL5
VDKCMDGNQPFPVLE	PPFIBP2	396	Q8ND30
VQKCLPPEIIMEYGE	NEK3	261	P51956
QCLNKMPPGEIKVDD	NDUFS2	346	O75306
ENGKMICSIPDNLPF	PCDHB4	376	Q9Y5E5
LGEEQIKPVNPVFCM	RABGGTB	301	P53611
EMPPEALSQGCKDIA	ALPL	191	P05186
MCNDDPDVLPDLKEA	OGDH	801	Q02218
LDGDDLGPMFLPCVL	PCDH15	256	Q96QU1
EILDFMLCGSDIEPP	BTBD18	496	B2RXH4
MKIQEDPSLCGDKPS	COMMD9	151	Q9P000
DGKCQPIEIPMCKDI	FZD10	31	Q9ULW2
KPLDPEMQCLLLSDG	SLC37A1	281	P57057
PEENKMAPCEFGVLN	HLA-DMB	56	P28068
PEFFLAGKQPCTNDM	FBH1	61	Q8NFZ0
MEEICGGDKPFLAPN	ATL1	371	Q8WXF7
DLENCMEEPPIFKGD	ARFGEF3	1921	Q5TH69
KFIDDMEDVLCPDPQ	COL6A2	796	P12110
DECNMELPPAALLFR	FAM120C	641	Q9NX05
LCEMAFPRVKPAPDE	ILF2	36	Q12905
PKVMLFDEPTTGLDC	ABCG5	211	Q9H222
CVPDVKALMESPEGQ	C17orf80	396	Q9BSJ5
PEINPEGFCILLDFM	BCL6	76	P41182
LAELVPMEYVGIPEC	BNIP2	281	Q12982
MCEAIKCPELFAPEQ	SELP	566	P16109
DCATLLKNMGPLPVD	MAST3	451	O60307
MDGCKKELPRLQEPE	GCNA	1	Q96QF7
PSEFCLGKFDEPLDM	SPAM1	56	P38567
DGVCIDAFLKPPMET	SPAM1	461	P38567
MNLPKGPDTLCFDKD	COG2	6	Q14746
SMDFFLLKCEGPGVP	DPP6	546	P42658
ILMEKIEPEPFENCL	GSS	396	P48637
QNPEAPMIECGFTKD	CFAP69	321	A5D8W1
AVCPEAELFVDPKMQ	DHX37	901	Q8IY37
CEQGCGLEMPKDELP	RNF41	116	Q9H4P4
GLEMPKDELPNHNCI	RNF41	121	Q9H4P4
CEEPVKDMLLAFPND	CFAP47	576	Q6ZTR5
LPEFNMAEPPLIFEC	EHMT1	1091	Q9H9B1
DFQFMPACIQKPEGL	EIF4G3	631	O43432
ILLPEVCMAPEEKGD	CNST	521	Q6PJW8
PPFNETECKMNEGIV	OTOGL	2236	Q3ZCN5
DLKQDVCEMPKETGP	EPPIN	71	O95925
CESPVSPIKMELLFD	NLRP3	196	Q96P20
CENDNLPKPVLDMLF	ARHGAP20	371	Q9P2F6
PEFLDMLEESPFLKC	RSBN1L	481	Q6PCB5
VEKELFALKPMNCPG	TARS1	401	P26639
CPPFKIVILDEADSM	RFC4	141	P35249
DQEPCLVDPDMIKAI	TINAGL1	136	Q9GZM7
DVKLPCEMDAQGPKQ	TES	191	Q9UGI8
GQFDPMIPDAECLKI	HARS2	181	P49590
QPPDGKSKDCMLQIV	PLEKHB2	66	Q96CS7
SELMLEKCPFPAGSD	SOCS5	211	O75159
DLTEDLPCVKMFAFP	TMEM132B	151	Q14DG7
LCENDEMILRKPEPG	TDRD15	521	B5MCY1
EDCPRMGEHQPLKVF	PRAMEF14	136	Q5SWL7
PFFCEDPETDNLMVK	PKNOX1	106	P55347
LMDDQVSGLPPCLKA	RECQL4	536	O94761
NECEKAPFAIMEPAG	NEXMIF	116	Q5QGS0
GDELPCDMRIPSDKQ	PREX1	1201	Q8TCU6
PCGMAEFKEKPEAPT	SETMAR	11	Q53H47
VLNPNPMDFCTKDLL	SETX	1906	Q7Z333
FGMDLAACIELIEKP	MYH4	516	Q9Y623
EDCPRMGEHQPLKVF	PRAMEF1	136	O95521
DCAKELFPPTALKME	SNED1	901	Q8TER0
LPELGCVEMTDLKAP	NCAPH	291	Q15003
PCLPDPKSQMEFEAQ	CLXN	186	Q9HAE3
LCMEPLEIDDINFFP	CNOT4	16	O95628
PEGGPEMAKEKQCYL	RNF213	4246	Q63HN8
MDFLKPTADCPDAVP	SMAD7	216	O15105
DLKLLCMKPGDAPSE	TEP1	2391	Q99973
TGELQEKMDPLPVAC	SSH2	1196	Q76I76
CPDIPQLEGLMKEIN	RYR3	3101	Q15413
DTIKDLLPNVCAFPM	SPINT3	26	P49223
LETAKEPCMAKFGPL	TNFSF18	51	Q9UNG2
EMFFKLSEEAECPNP	STK10	936	O94804
EALMECKAKPVGSPL	PHF3	271	Q92576
DGMVCLPKDPCTDNL	STAB1	266	Q9NY15
VCGLIVPQEDMPFCD	POLR3B	906	Q9NW08
FKLLDPPNMGQDICF	TGM5	511	O43548
GPICLQDPLDKELMT	UNC5D	456	Q6UXZ4
KPCIADFMPILGTNL	TNPO1	711	Q92973
EMQDLCFLGPFEDPV	ZNF469	3026	Q96JG9
DMKCYLLEPENSGPE	USP3	436	Q9Y6I4
VNCPIADFLMKAPEP	YTHDC2	786	Q9H6S0
PCMNDLKFPVVVLDE	ZGRF1	1796	Q86YA3
QGICKEEPAQEPIME	ZNF74	126	Q16587
ICAPLGPKYMAEAVQ	ZDHHC19	251	Q8WVZ1
PQMLLTGEKPYKCDE	ZNF713	276	Q8N859
GCLENMPEADCIPKE	PLK2	481	Q9NYY3
DEFICPITRELMKDP	WDSUB1	406	Q8N9V3
KNGQAPETCPFFEEM	ZSCAN29	476	Q8IWY8
VEGPKEFPQEKMCLR	THOC5	646	Q13769
PCLPKEGIFAVDTML	TRIP12	736	Q14669
FPESGQPECLKEMNL	ZNF512	316	Q96ME7
CSIKMEAEPAEPLAA	SMTN	541	P53814
VKQEDSLFASMPPLC	YEATS2	551	Q9ULM3
PEEDCMQLNPSFKGI	PLPP7	66	Q8NBV4
KPIPILAAGFCSDKM	WDR43	331	Q15061
DVPGDKLLEPVVCMS	VPS4A	391	Q9UN37