Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein tyrosine phosphatase activity

DUSP2 DUSP7 DUSP9 PTPN21 DNAJC6 DUSP22 PTPN1 DUSP26 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS DUSP16

2.21e-2110315119GO:0004725
GeneOntologyMolecularFunctionphosphoprotein phosphatase activity

DUSP2 DUSP7 DUSP9 PTPN21 DNAJC6 DUSP22 PTPN1 DUSP26 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS PPM1F DUSP16

1.71e-1718915120GO:0004721
GeneOntologyMolecularFunctionphosphatase activity

IMPA2 DUSP2 DUSP7 DUSP9 PTPN21 DNAJC6 DUSP22 PTPN1 DUSP26 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS PPM1F DUSP16

4.79e-1528715121GO:0016791
GeneOntologyMolecularFunctionphosphoric ester hydrolase activity

PDE2A IMPA2 DUSP2 DUSP7 DUSP9 PTPN21 DNAJC6 DUSP22 PTPN1 DUSP26 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS PPM1F DUSP16

1.73e-1338615122GO:0042578
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

PDE2A IMPA2 DUSP2 DUSP7 DUSP9 EXOSC5 PTPN21 DNAJC6 DUSP22 PTPN1 DUSP26 PTPN6 FASN PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS PPM1F NYNRIN DUSP16 POP1

3.72e-1080715126GO:0016788
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPN6 PTPRA PTPRB PTPRD PTPRE PTPRF

1.96e-09171516GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPN6 PTPRA PTPRB PTPRD PTPRE PTPRF

1.96e-09171516GO:0019198
GeneOntologyMolecularFunctionnon-membrane spanning protein tyrosine phosphatase activity

DUSP22 PTPN1 PTPN6 PTPN9 PTPN11

1.76e-08121515GO:0004726
GeneOntologyMolecularFunctionprotein tyrosine/serine/threonine phosphatase activity

DUSP2 DUSP7 DUSP9 DUSP22 DUSP26 PPM1F DUSP16

3.15e-08431517GO:0008138
GeneOntologyMolecularFunctionMAP kinase phosphatase activity

DUSP2 DUSP7 DUSP9 DUSP26 DUSP16

1.83e-07181515GO:0033549
GeneOntologyMolecularFunctionMAP kinase tyrosine phosphatase activity

DUSP2 DUSP7 DUSP9 DUSP16

6.37e-07101514GO:0033550
GeneOntologyMolecularFunctionprotein tyrosine/threonine phosphatase activity

DUSP2 DUSP7 DUSP9 DUSP16

9.95e-07111514GO:0008330
GeneOntologyMolecularFunctionMAP kinase tyrosine/serine/threonine phosphatase activity

DUSP2 DUSP7 DUSP9 DUSP16

2.13e-06131514GO:0017017
GeneOntologyMolecularFunctionmyosin phosphatase activity

DUSP2 DUSP7 DUSP9 DUSP22 DUSP26 PPM1F DUSP16

3.71e-06851517GO:0017018
GeneOntologyMolecularFunctionprotein serine/threonine phosphatase activity

DUSP2 DUSP7 DUSP9 DUSP22 DUSP26 PPM1F DUSP16

1.92e-051091517GO:0004722
GeneOntologyMolecularFunctionacetyl-CoA carboxylase activity

ACACA ACACB

5.68e-0521512GO:0003989
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

ABCC1 SLC22A25 ABCC11 SLC7A14 SLC27A2

6.07e-04901515GO:0008028
GeneOntologyMolecularFunctionfatty acid transmembrane transporter activity

ABCC1 SLC22A25 SLC27A2

6.72e-04231513GO:0015245
GeneOntologyMolecularFunctionCoA carboxylase activity

ACACA ACACB

8.35e-0461512GO:0016421
GeneOntologyMolecularFunctionbiotin binding

ACACA ACACB

8.35e-0461512GO:0009374
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

ABCC1 SLC22A25 SLC26A2 ABCC11 SLC7A14 SLC26A1 SLC27A2

1.02e-032071517GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

ABCC1 SLC22A25 SLC26A2 ABCC11 SLC7A14 SLC26A1 SLC27A2

1.05e-032081517GO:0005342
GeneOntologyMolecularFunctionligase activity, forming carbon-carbon bonds

ACACA ACACB

1.16e-0371512GO:0016885
GeneOntologyMolecularFunctionsulfur compound transmembrane transporter activity

ABCC1 SLC26A2 ABCC11 SLC26A1

1.17e-03611514GO:1901682
GeneOntologyMolecularFunctioninsulin receptor binding

PTPN1 PTPN11 PTPRF

1.48e-03301513GO:0005158
GeneOntologyMolecularFunctionABC-type glutathione S-conjugate transporter activity

ABCC1 ABCC11

1.54e-0381512GO:0015431
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

ABCC1 SLC26A2 ABCC11 SLC26A1 SLC20A2 APOL4

1.93e-031711516GO:0015103
GeneOntologyMolecularFunctionATPase-coupled lipid transmembrane transporter activity

ABCC1 ABCC11

1.98e-0391512GO:0034040
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCC1 SLC22A25 ABCC11 SLC27A2

2.28e-03731514GO:0170055
GeneOntologyMolecularFunctionmitogen-activated protein kinase binding

DUSP2 PTPRJ DUSP16

2.32e-03351513GO:0051019
GeneOntologyMolecularFunctionoxalate transmembrane transporter activity

SLC26A2 SLC26A1

2.46e-03101512GO:0019531
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC1 ABCC11

2.46e-03101512GO:0043225
GeneOntologyMolecularFunctionadrenergic receptor activity

GPR88 ADRA1D

2.46e-03101512GO:0004935
GeneOntologyMolecularFunctionsecondary active sulfate transmembrane transporter activity

SLC26A2 SLC26A1

2.99e-03111512GO:0008271
GeneOntologyBiologicalProcesspeptidyl-tyrosine dephosphorylation

DUSP2 DUSP7 DUSP9 DUSP22 PTPN1 PTPN6 PTPN9 PTPN11 PTPRB PTPRF PTPRJ PTPRS DUSP16

8.33e-203415113GO:0035335
GeneOntologyBiologicalProcessprotein dephosphorylation

DUSP2 DUSP7 DUSP9 PTPN21 DUSP22 PTPN1 DUSP26 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS PPM1F DUSP16 HTT

3.52e-1525615120GO:0006470
GeneOntologyBiologicalProcessdephosphorylation

DUSP2 DUSP7 DUSP9 PTPN21 DNAJC6 DUSP22 PTPN1 DUSP26 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS PPM1F DUSP16 HTT

1.09e-1334715121GO:0016311
GeneOntologyBiologicalProcessregulation of focal adhesion assembly

CLASP1 DUSP22 PTPN11 PTPRA PTPRJ PPM1F

1.24e-05701516GO:0051893
GeneOntologyBiologicalProcessregulation of cell-substrate junction assembly

CLASP1 DUSP22 PTPN11 PTPRA PTPRJ PPM1F

1.24e-05701516GO:0090109
GeneOntologyBiologicalProcesscell surface receptor protein tyrosine phosphatase signaling pathway

PTPRD PTPRE PTPRF

1.32e-0571513GO:0007185
GeneOntologyBiologicalProcessregulation of cell-substrate junction organization

CLASP1 DUSP22 PTPN11 PTPRA PTPRJ PPM1F

1.85e-05751516GO:0150116
GeneOntologyBiologicalProcessregulation of MAPK cascade

TRAF7 RAP1GDS1 DUSP2 DUSP7 DUSP9 DUSP22 PTPN1 DUSP26 RASGRP1 PTPN6 ADRA1D PTPN11 PTPRJ FZD5 DUSP16 FGF7 SOD1 FBXW7

2.99e-0581515118GO:0043408
GeneOntologyBiologicalProcessregulation of protein kinase activity

RELN DUSP7 DUSP22 TNFRSF4 CEMIP PTPN1 RASGRP1 PTPN6 PTPRB PTPRJ FZD5 PPM1F SOD1 HTT FBXW7

4.40e-0561115115GO:0045859
GeneOntologyBiologicalProcesspeptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

PTPN1 PTPRB PTPRJ

4.44e-05101513GO:1990264
GeneOntologyBiologicalProcessmalonyl-CoA biosynthetic process

ACACA ACACB

5.32e-0521512GO:2001295
GeneOntologyBiologicalProcessnegative regulation of T cell receptor signaling pathway

UBASH3A DUSP22 PTPN6 PTPRJ

5.68e-05291514GO:0050860
GeneOntologyBiologicalProcesspostsynaptic density organization

SHANK1 RELN RAPSN PTPRD PTPRS

6.60e-05581515GO:0097106
GeneOntologyBiologicalProcessfocal adhesion assembly

CLASP1 DUSP22 PTPN11 PTPRA PTPRJ PPM1F

7.96e-05971516GO:0048041
GeneOntologyBiologicalProcessnegative regulation of MAPK cascade

DUSP2 DUSP7 DUSP9 PTPN1 DUSP26 PTPN6 PTPRJ DUSP16

1.20e-042011518GO:0043409
GeneOntologyBiologicalProcesscell-substrate junction assembly

CLASP1 DUSP22 PTPN11 PTPRA PTPRJ PPM1F

1.44e-041081516GO:0007044
GeneOntologyBiologicalProcessregulation of kinase activity

RELN DUSP7 DUSP22 TNFRSF4 CEMIP PTPN1 RASGRP1 PTPN6 PTPRB PTPRJ FZD5 PPM1F SOD1 HTT FBXW7

1.59e-0468615115GO:0043549
GeneOntologyBiologicalProcessMAPK cascade

TRAF7 RAP1GDS1 DUSP2 DUSP7 DUSP9 DUSP22 PTPN1 DUSP26 RASGRP1 PTPN6 ADRA1D PTPN11 PTPRJ FZD5 DUSP16 FGF7 SOD1 FBXW7

1.60e-0493015118GO:0000165
GeneOntologyBiologicalProcessnegative regulation of antigen receptor-mediated signaling pathway

UBASH3A DUSP22 PTPN6 PTPRJ

1.68e-04381514GO:0050858
GeneOntologyBiologicalProcessregulation of mitophagy

VPS13C FZD5 HTT FBXW7

1.68e-04381514GO:1901524
GeneOntologyBiologicalProcesspostsynaptic specialization organization

SHANK1 RELN RAPSN PTPRD PTPRS

1.74e-04711515GO:0099084
GeneOntologyBiologicalProcesscell-substrate junction organization

CLASP1 DUSP22 PTPN11 PTPRA PTPRJ PPM1F

2.03e-041151516GO:0150115
GeneOntologyBiologicalProcessnegative regulation of intracellular signal transduction

PDE2A RIPOR2 DUSP2 NLRX1 CYP26A1 DUSP7 DUSP9 PTPN1 DUSP26 PTPN6 PTPRJ PTPRS DUSP16 SIGLEC11 ALG13 FBXW7

2.45e-0479515116GO:1902532
GeneOntologyBiologicalProcessregulation of immune effector process

PGLYRP4 NLRX1 DUSP22 TNFRSF4 JAK3 RASGRP1 PTPN6 MS4A2 FZD5 XCL2 ANKRD17 SIGLEC11

3.04e-0449715112GO:0002697
GeneOntologyBiologicalProcessregulation of autophagy of mitochondrion

VPS13C FZD5 HTT FBXW7

3.26e-04451514GO:1903146
MousePhenoabnormal vitelline vascular remodeling

PTPN11 PTPRB ARAP3 PTPRJ FZD5 FBXW7

1.68e-05611256MP:0004076
DomainTYR_PHOSPHATASE_1

DUSP2 DUSP7 DUSP9 PTPN21 DNAJC6 DUSP22 PTPN1 DUSP26 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS DUSP16

2.16e-228615219PS00383
DomainTYR_PHOSPHATASE_dom

DUSP2 DUSP7 DUSP9 PTPN21 DNAJC6 DUSP22 PTPN1 DUSP26 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS DUSP16

2.74e-228715219IPR000387
DomainTYR_PHOSPHATASE_2

DUSP2 DUSP7 DUSP9 PTPN21 DNAJC6 DUSP22 PTPN1 DUSP26 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS DUSP16

2.74e-228715219PS50056
Domain-

DUSP2 DUSP7 DUSP9 PTPN21 DNAJC6 DUSP22 PTPN1 DUSP26 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS DUSP16

8.67e-2292152193.90.190.10
DomainProt-tyrosine_phosphatase-like

DUSP2 DUSP7 DUSP9 PTPN21 DNAJC6 DUSP22 PTPN1 DUSP26 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS DUSP16

3.87e-219915219IPR029021
DomainTyr_Pase_AS

DUSP2 PTPN21 PTPN1 DUSP26 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS DUSP16

2.18e-177315215IPR016130
DomainPTPc

PTPN21 PTPN1 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS

5.75e-173615212SM00194
DomainTYR_PHOSPHATASE_PTP

PTPN21 PTPN1 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS

1.76e-163915212PS50055
DomainPTPase_domain

PTPN21 PTPN1 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS

3.50e-164115212IPR000242
DomainY_phosphatase

PTPN21 PTPN1 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS

3.50e-164115212PF00102
DomainPTPc_motif

DUSP2 PTPN21 PTPN1 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS

1.20e-155915213SM00404
DomainTyr_Pase_cat

DUSP2 PTPN21 PTPN1 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS

1.20e-155915213IPR003595
DomainDUSP

DUSP2 DUSP7 DUSP9 DUSP22 DUSP26 DUSP16

1.64e-07311526IPR024950
DomainTYR_PHOSPHATASE_DUAL

DUSP2 DUSP7 DUSP9 DUSP22 DUSP26 DUSP16

2.93e-07341526PS50054
DomainDSPc

DUSP2 DUSP7 DUSP9 DUSP22 DUSP26 DUSP16

3.52e-07351526SM00195
DomainTYR_PHOSPHATASE_DUAL_dom

DUSP2 DUSP7 DUSP9 DUSP22 DUSP26 DUSP16

3.52e-07351526IPR020422
DomainMKP

DUSP2 DUSP7 DUSP9 DUSP16

8.52e-07101524IPR008343
DomainDual-sp_phosphatase_cat-dom

DUSP2 DUSP7 DUSP9 DUSP22 DUSP26 DUSP16

9.35e-07411526IPR000340
DomainDSPc

DUSP2 DUSP7 DUSP9 DUSP22 DUSP26 DUSP16

9.35e-07411526PF00782
DomainRHOD

DUSP2 DUSP7 DUSP9 DUSP16

2.75e-05221524SM00450
DomainRHODANESE_3

DUSP2 DUSP7 DUSP9 DUSP16

3.31e-05231524PS50206
DomainRhodanese-like_dom

DUSP2 DUSP7 DUSP9 DUSP16

3.95e-05241524IPR001763
DomainRhodanese

DUSP2 DUSP7 DUSP9 DUSP16

3.95e-05241524PF00581
Domain-

DUSP2 DUSP7 DUSP9 DUSP16

3.95e-052415243.40.250.10
DomainACC_central

ACACA ACACB

6.58e-0521522PF08326
DomainTyr_Pase_rcpt_a/e-type

PTPRA PTPRE

6.58e-0521522IPR016336
DomainTyr_Pase_non-rcpt_typ-6/11

PTPN6 PTPN11

6.58e-0521522IPR012152
DomainAcCoA_COase_cen

ACACA ACACB

6.58e-0521522IPR013537
DomainIg_I-set

MYLK FSTL4 OBSL1 PTPRD PTPRF PTPRS SIGLEC11 SIGLEC1

1.67e-041901528IPR013098
DomainI-set

MYLK FSTL4 OBSL1 PTPRD PTPRF PTPRS SIGLEC11 SIGLEC1

1.67e-041901528PF07679
DomainPH_dom-like

ACAP1 CNKSR1 CDC42BPA NBEAL1 PTPN21 TIAM2 PLEKHH1 JAK3 ARAP3 PLEKHH2 ACAP2 TECPR1

1.95e-0442615212IPR011993
Domainfn3

MYLK OBSL1 PTPRB PTPRD PTPRF PTPRJ PTPRS

3.66e-041621527PF00041
DomainAnk_2

SHANK1 ANKRD31 ACAP1 ANKS6 ACBD6 ANKAR ANKRD17 ACAP2

3.84e-042151528PF12796
DomainCarboxyl_trans

ACACA ACACB

3.91e-0441522PF01039
DomainCOA_CT_CTER

ACACA ACACB

3.91e-0441522PS50989
DomainCOA_CT_NTER

ACACA ACACB

3.91e-0441522PS50980
DomainCOA_CT_N

ACACA ACACB

3.91e-0441522IPR011762
DomainCOA_CT_C

ACACA ACACB

3.91e-0441522IPR011763
DomainCarboxyl_trans

ACACA ACACB

3.91e-0441522IPR000022
Domain-

TRAF7 NWD1 NBEAL1 WDR46 FSTL4 SEMA3G FBXW5 NLE1 WDFY1 FBXW7

4.07e-04333152102.130.10.10
DomainWD40/YVTN_repeat-like_dom

TRAF7 NWD1 NBEAL1 WDR46 FSTL4 SEMA3G FBXW5 NLE1 WDFY1 FBXW7

4.27e-0433515210IPR015943
DomainPH

ACAP1 CNKSR1 CDC42BPA TIAM2 PLEKHH1 ARAP3 PLEKHH2 ACAP2 TECPR1

4.63e-042781529SM00233
DomainPH_DOMAIN

ACAP1 CNKSR1 CDC42BPA TIAM2 PLEKHH1 ARAP3 PLEKHH2 ACAP2 TECPR1

4.75e-042791529PS50003
DomainPH_domain

ACAP1 CNKSR1 CDC42BPA TIAM2 PLEKHH1 ARAP3 PLEKHH2 ACAP2 TECPR1

4.88e-042801529IPR001849
DomainPH

ACAP1 CNKSR1 CDC42BPA TIAM2 PLEKHH1 ARAP3 PLEKHH2 ACAP2

5.84e-042291528PF00169
DomainCAT3

SLC7A14 SLC7A4

6.47e-0451522IPR015606
DomainAA_permease_C

SLC7A14 SLC7A4

6.47e-0451522PF13906
DomainBiotin_BS

ACACA ACACB

6.47e-0451522IPR001882
DomainBiotin_COase_C

ACACA ACACB

6.47e-0451522IPR005482
DomainBC

ACACA ACACB

6.47e-0451522PS50979
DomainBiotin_carb_C

ACACA ACACB

6.47e-0451522SM00878
DomainBiotin_carb_C

ACACA ACACB

6.47e-0451522PF02785
DomainBiotin_carboxylation_dom

ACACA ACACB

6.47e-0451522IPR011764
DomainCPSASE_1

ACACA ACACB

6.47e-0451522PS00866
DomainCAT_C

SLC7A14 SLC7A4

6.47e-0451522IPR029485
DomainBIOTIN

ACACA ACACB

6.47e-0451522PS00188
Domain-

PTPN21 ACBD6 PLEKHH1 PLEKHH2

6.72e-044915241.20.80.10
DomainFERM_domain

PTPN21 PLEKHH1 JAK3 PLEKHH2

6.72e-04491524IPR000299
DomainIGc2

MYLK FSTL4 OBSL1 PTPRD PTPRF PTPRS SIGLEC11 SIGLEC1

6.91e-042351528SM00408
DomainIg_sub2

MYLK FSTL4 OBSL1 PTPRD PTPRF PTPRS SIGLEC11 SIGLEC1

6.91e-042351528IPR003598
DomainFERM/acyl-CoA-bd_prot_3-hlx

PTPN21 ACBD6 PLEKHH1 PLEKHH2

7.26e-04501524IPR014352
DomainFERM_1

PTPN21 PLEKHH1 JAK3 PLEKHH2

7.26e-04501524PS00660
DomainFERM_2

PTPN21 PLEKHH1 JAK3 PLEKHH2

7.26e-04501524PS00661
DomainFERM_3

PTPN21 PLEKHH1 JAK3 PLEKHH2

7.26e-04501524PS50057
DomainBand_41_domain

PTPN21 PLEKHH1 JAK3 PLEKHH2

7.26e-04501524IPR019749
DomainB41

PTPN21 PLEKHH1 JAK3 PLEKHH2

7.26e-04501524SM00295
DomainFN3

MYLK OBSL1 PTPRB PTPRD PTPRF PTPRJ PTPRS

8.08e-041851527SM00060
Domainig

FSTL4 OBSL1 SEMA3G PTPRD PTPRS SIGLEC11 SIGLEC1

9.45e-041901527PF00047
DomainImmunoglobulin

FSTL4 OBSL1 SEMA3G PTPRD PTPRS SIGLEC11 SIGLEC1

9.45e-041901527IPR013151
DomainRudment_hybrid_motif

ACACA ACACB

9.66e-0461522IPR011054
DomainCPSASE_2

ACACA ACACB

9.66e-0461522PS00867
Domain-

SHANK1 ANKRD31 ACAP1 ANKS6 ACBD6 ANKAR ANKRD17 ACAP2

9.80e-0424815281.25.40.20
DomainANK

SHANK1 ANKRD31 ACAP1 ANKS6 ACBD6 ANKAR ANKRD17 ACAP2

1.06e-032511528SM00248
DomainANK_REPEAT

SHANK1 ANKRD31 ACAP1 ANKS6 ACBD6 ANKAR ANKRD17 ACAP2

1.11e-032531528PS50088
DomainAnkyrin_rpt-contain_dom

SHANK1 ANKRD31 ACAP1 ANKS6 ACBD6 ANKAR ANKRD17 ACAP2

1.14e-032541528IPR020683
DomainANK_REP_REGION

SHANK1 ANKRD31 ACAP1 ANKS6 ACBD6 ANKAR ANKRD17 ACAP2

1.14e-032541528PS50297
DomainFN3

MYLK OBSL1 PTPRB PTPRD PTPRF PTPRJ PTPRS

1.24e-031991527PS50853
DomainWD40

TRAF7 NWD1 NBEAL1 WDR46 FBXW5 NLE1 WDFY1 FBXW7

1.29e-032591528PF00400
DomainS04_transporter_CS

SLC26A2 SLC26A1

1.35e-0371522IPR018045
DomainCbamoylP_synth_lsu-like_ATP-bd

ACACA ACACB

1.35e-0371522IPR005479
DomainBC-like_N

ACACA ACACB

1.35e-0371522IPR005481
DomainCPSase_L_D2

ACACA ACACB

1.35e-0371522PF02786
DomainBiotin_carb_N

ACACA ACACB

1.35e-0371522PF00289
Domain-

ACAP1 CNKSR1 CDC42BPA PTPN21 TIAM2 PLEKHH1 ARAP3 PLEKHH2 ACAP2 TECPR1

1.39e-03391152102.30.29.30
DomainAnkyrin_rpt

SHANK1 ANKRD31 ACAP1 ANKS6 ACBD6 ANKAR ANKRD17 ACAP2

1.39e-032621528IPR002110
DomainWD40

TRAF7 NWD1 NBEAL1 WDR46 FBXW5 NLE1 WDFY1 FBXW7

1.60e-032681528SM00320
DomainFN3_dom

MYLK OBSL1 PTPRB PTPRD PTPRF PTPRJ PTPRS

1.64e-032091527IPR003961
DomainArfGap

ACAP1 ARAP3 ACAP2

1.65e-03291523SM00105
DomainARFGAP

ACAP1 ARAP3 ACAP2

1.65e-03291523PS50115
DomainArfGap

ACAP1 ARAP3 ACAP2

1.65e-03291523PF01412
DomainArfGAP

ACAP1 ARAP3 ACAP2

1.65e-03291523IPR001164
DomainARM-like

RIPOR2 RAP1GDS1 CLASP1 FHOD1 ANKAR HEATR5B AGBL1 HTT

1.68e-032701528IPR011989
DomainWD40_repeat

TRAF7 NWD1 NBEAL1 WDR46 FBXW5 NLE1 WDFY1 FBXW7

1.76e-032721528IPR001680
DomainARM-type_fold

RIPOR2 RAP1GDS1 CLASP1 NBEAL1 FHOD1 ANKAR HEATR5B AGBL1 HTT

1.86e-033391529IPR016024
DomainWD_REPEATS_1

TRAF7 NWD1 NBEAL1 WDR46 FBXW5 NLE1 WDFY1 FBXW7

2.02e-032781528PS00678
DomainWD_REPEATS_2

TRAF7 NWD1 NBEAL1 WDR46 FBXW5 NLE1 WDFY1 FBXW7

2.06e-032791528PS50082
DomainWD_REPEATS_REGION

TRAF7 NWD1 NBEAL1 WDR46 FBXW5 NLE1 WDFY1 FBXW7

2.06e-032791528PS50294
DomainMYTH4

PLEKHH1 PLEKHH2

2.28e-0391522PS51016
DomainMyTH4

PLEKHH1 PLEKHH2

2.28e-0391522SM00139
DomainBiotin_lipoyl

ACACA ACACB

2.28e-0391522PF00364
PathwayREACTOME_RAF_INDEPENDENT_MAPK1_3_ACTIVATION

DUSP2 DUSP7 DUSP9 PTPN11 DUSP16

8.87e-07221185MM14506
PathwayREACTOME_RAF_INDEPENDENT_MAPK1_3_ACTIVATION

DUSP2 DUSP7 DUSP9 PTPN11 DUSP16

1.13e-06231185M26917
PathwayREACTOME_SIGNALING_BY_MAPK_MUTANTS

DUSP7 DUSP9 DUSP16

1.95e-0571183M38997
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PTP

DUSP2 DUSP7 DUSP9 DUSP16

2.04e-05201184M47928
PathwayREACTOME_CHREBP_ACTIVATES_METABOLIC_GENE_EXPRESSION

ACACA ACACB FASN

3.11e-0581183M26991
PathwayREACTOME_REGULATION_OF_IFNG_SIGNALING

PTPN1 PTPN6 PTPN11

1.95e-04141183M942
Pubmed

Protein tyrosine phosphatases expression during development of mouse superior colliculus.

PTPN1 PTPN6 PTPN9 PTPN11 PTPRA PTPRD PTPRE PTPRF PTPRJ PTPRS

3.81e-20171531019727691
Pubmed

A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.

PTPN1 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRS

9.03e-151115377832766
Pubmed

Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases.

PTPRA PTPRD PTPRE PTPRF PTPRS

3.22e-117153512376545
Pubmed

Identification and typing of members of the protein-tyrosine phosphatase gene family expressed in mouse brain.

PTPRA PTPRB PTPRE PTPRF PTPRS

3.22e-11715351454056
Pubmed

Identification of novel protein tyrosine phosphatases of hematopoietic cells by polymerase chain reaction amplification.

PTPN1 PTPN6 PTPRA PTPRE PTPRJ

3.22e-11715351932742
Pubmed

Cloning and characterization of PTP-K1, a novel nonreceptor protein tyrosine phosphatase highly expressed in bone marrow.

PTPN1 PTPN6 PTPN11 PTPRA PTPRE PTPRF

5.07e-111615368875997
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

CLASP1 DUSP2 DUSP7 DUSP9 OBSL1 PTPN21 DNAJC6 DUSP22 NDUFA11 CNNM4 PTPN1 DUSP26 PTPN6 FASN PTPN9 PTPN11 PTPRA ARAP3 PTPRD PTPRF PTPRS DUSP16 ANKRD17

5.72e-119741532328675297
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ABCC1 DDX31 CDC42BPA DUSP2 DUSP9 PTPN21 DUSP22 CNNM4 PTPN1 DUSP26 PTPN6 PTPN9 PTPN11 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS PPM1F DUSP16 FBXW7

2.44e-1010491532327880917
Pubmed

Dynamic changes in the expression of protein tyrosine phosphatases during preimplantation mouse development: semi-quantification by real-time PCR.

PTPN6 PTPN11 PTPRF PTPRS

3.60e-104153414967925
Pubmed

Multiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine phosphatase domains of various RPTPs.

PTPRA PTPRD PTPRF PTPRS

1.79e-095153410777529
Pubmed

Substrate-trapping techniques in the identification of cellular PTP targets.

JAK3 PTPN1 PTPN6 PTPN11 PTPRA PTPRE PTPRF

2.04e-0949153715588985
Pubmed

Structural diversity and evolution of human receptor-like protein tyrosine phosphatases.

PTPRA PTPRB PTPRD PTPRE

5.36e-09615342170109
Pubmed

Some protein tyrosine phosphatases target in part to lipid rafts and interact with caveolin-1.

PTPN1 PTPN6 PTPN11 PTPRF

5.36e-096153412176037
Pubmed

Expression of protein tyrosine phosphatase genes in the developing brain of mouse and rat.

PTPN1 PTPN6 PTPRB PTPRF

1.25e-08715347804149
Pubmed

Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor.

DUSP7 PTPN1 PTPN9 PTPRB

4.46e-089153412907755
Pubmed

Large-scale structural analysis of the classical human protein tyrosine phosphatome.

PTPN1 PTPN6 PTPN9 PTPRB PTPRE PTPRJ

6.08e-0847153619167335
Pubmed

Syk-independent tyrosine phosphorylation and association of the protein tyrosine phosphatases SHP-1 and SHP-2 with the high affinity IgE receptor.

PTPN6 PTPN11 MS4A2

8.35e-08315339379041
Pubmed

LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.

PTPRD PTPRF PTPRS

8.35e-083153331985401
Pubmed

Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.

PTPRD PTPRF PTPRS

8.35e-083153320139422
Pubmed

Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.

PTPRD PTPRF PTPRS

8.35e-083153333656439
Pubmed

Differential activation of recombinant human acetyl-CoA carboxylases 1 and 2 by citrate.

ACACA ACACB FASN

8.35e-083153318455495
Pubmed

Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.

PTPRD PTPRF PTPRS

8.35e-08315339784606
Pubmed

The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.

PTPRD PTPRF PTPRS

3.33e-07415338524829
Pubmed

LAIR-1, a novel inhibitory receptor expressed on human mononuclear leukocytes.

LAIR1 PTPN6 PTPN11

3.33e-07415339285412
Pubmed

Src kinase activity is regulated by the SHP-1 protein-tyrosine phosphatase.

PTPN1 PTPN6 PTPRA

3.33e-07415339261115
Pubmed

Subcellular localization of intracellular protein tyrosine phosphatases in T cells.

PTPN1 PTPN6 PTPN9 PTPN11

3.48e-0714153410940933
Pubmed

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.

TRAF7 RAP1GDS1 DUSP2 DUSP7 DUSP9 PTPN21 DUSP22 NDUFA11 CNNM4 PTPN1 DUSP26 PTPN6 PTPN9 PTPN11 PTPRA PTPRE DUSP16

8.25e-079311531727432908
Pubmed

Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program.

ACACA ACACB FASN

8.29e-075153337163372
Pubmed

FDF03, a novel inhibitory receptor of the immunoglobulin superfamily, is expressed by human dendritic and myeloid cells.

LAIR1 PTPN6 PTPN11

8.29e-075153310903717
Pubmed

Identification of protein tyrosine phosphatases expressed in murine male germ cells.

PTPN1 PTPRD PTPRE

8.29e-07515338267598
Pubmed

Characterization of inhibitory signaling motifs of the natural killer cell receptor Siglec-7: attenuated recruitment of phosphatases by the receptor is attributed to two amino acids in the motifs.

LAIR1 PTPN6 PTPN11

8.29e-075153315703304
Pubmed

Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule.

PTPRD PTPRF PTPRS

8.29e-075153322357843
Pubmed

Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases.

PTPRD PTPRF PTPRS

1.65e-066153319273906
Pubmed

Cloning and characterization of human Siglec-11. A recently evolved signaling molecule that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages, including brain microglia.

PTPN6 PTPN11 SIGLEC11

1.65e-066153311986327
Pubmed

Expression and subcellular distribution of the active form of c-Src tyrosine kinase in differentiating human endometrial stromal cells.

PTPN1 PTPN6 PTPRA

1.65e-066153312468645
Pubmed

CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP.

CNKSR1 DUSP7 PTPN6 PTPRJ

2.48e-0622153434187934
Pubmed

Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).

ACACA ACACB FASN SLC27A2

2.48e-0622153420965718
Pubmed

Modulation of apoptotic response by LAR family phosphatases-cIAP1 signaling during urinary tract morphogenesis.

PTPRD PTPRF PTPRS

2.88e-067153329073098
Pubmed

Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein.

PTPN1 PTPN11 PTPRF

2.88e-067153310660596
Pubmed

PILRalpha, a novel immunoreceptor tyrosine-based inhibitory motif-bearing protein, recruits SHP-1 upon tyrosine phosphorylation and is paired with the truncated counterpart PILRbeta.

LAIR1 PTPN6 PTPN11

2.88e-067153310660620
Pubmed

Modulation of the SH2 binding specificity and kinase activity of Src by tyrosine phosphorylation within its SH2 domain.

PTPN1 PTPN6 PTPRA

4.60e-06815338647855
Pubmed

Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.

PTPRD PTPRF PTPRS

4.60e-068153337591863
Pubmed

Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.

PTPRD PTPRF PTPRS

4.60e-068153328637841
Pubmed

Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform.

PTPRA PTPRD PTPRF PTPRS

4.99e-0626153436178190
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

FSTL4 OBSL1 PTPRA PTPRD PTPRF PTPRS SIGLEC1

8.01e-06162153725826454
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TRAF7 PDE2A ANKS6 CDC42BPA ACACA NLRX1 AGPAT2 TIAM2 JAK3 FASN SLC8B1 ARAP3 PTPRF PTPRS DUSP16 NLE1 HTT

8.10e-0611051531735748872
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

ACACB DUSP7 DUSP22 CNNM4 PTPN1 PTPN6 PTPRA PTPRE PTPRF DUSP16 HEATR5B ATP5F1C

9.59e-065731531228330616
Pubmed

The mahogany protein is a receptor involved in suppression of obesity.

ADRA1D PTPRA SIGLEC1

9.79e-0610153310086355
Pubmed

PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission.

PTPRD PTPRF PTPRS

1.34e-0511153325624497
Pubmed

Roles of Collagen XXV and Its Putative Receptors PTPσ/δ in Intramuscular Motor Innervation and Congenital Cranial Dysinnervation Disorder.

PTPRA PTPRD PTPRS

1.78e-0512153331875546
Pubmed

Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.

PTPRD PTPRF PTPRS

1.78e-051215339624153
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

ACACB DUSP9 DUSP26 PTPN6 PTPN11 PTPRA PTPRB PPM1F DUSP16 PRSS42P

1.84e-054201531028065597
Pubmed

Synergistic OX40 and CD30 signals sustain CD8+ T cells during antigenic challenge.

TNFRSF4 TNFRSF8

1.92e-052153219609980
Pubmed

Analysis of multigene families by DNA fingerprinting of conserved domains: directed cloning of tissue-specific protein tyrosine phosphatases.

PTPN11 PTPRS

1.92e-05215328479755
Pubmed

ACAPs are arf6 GTPase-activating proteins that function in the cell periphery.

ACAP1 ACAP2

1.92e-052153211062263
Pubmed

Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis.

PTPN1 PTPN11

1.92e-052153222389718
Pubmed

Concomitant deletion of Ptpn6 and Ptpn11 in T cells fails to improve anticancer responses.

PTPN6 PTPN11

1.92e-052153236194675
Pubmed

Chromosomal location of murine protein tyrosine phosphatase (Ptprj and Ptpre) genes.

PTPRE PTPRJ

1.92e-05215328575779
Pubmed

Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development.

PTPN6 PTPN11

1.92e-052153211159516
Pubmed

Expression of CD30 and Ox40 on T lymphocyte subsets is controlled by distinct regulatory mechanisms.

TNFRSF4 TNFRSF8

1.92e-052153214634058
Pubmed

Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation.

ACACA ACACB

1.92e-052153224944901
Pubmed

Oxidation sensitivity of the catalytic cysteine of the protein-tyrosine phosphatases SHP-1 and SHP-2.

PTPN6 PTPN11

1.92e-052153217561098
Pubmed

Hormonal regulation of acetyl-CoA carboxylase isoenzyme gene transcription.

ACACA ACACB

1.92e-052153220139635
Pubmed

Expression of protein-tyrosine phosphatases in the major insulin target tissues.

PTPRA PTPRS

1.92e-05215329357975
Pubmed

Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) Reduces Proliferation and De Novo Lipogenesis of EGFRvIII Human Glioblastoma Cells.

ACACA ACACB

1.92e-052153228081256
Pubmed

Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats.

ACACA ACACB

1.92e-052153226976583
Pubmed

The immune checkpoint receptor associated phosphatases SHP-1 and SHP-2 are not required for γδT17 cell development, activation, or skin inflammation.

PTPN6 PTPN11

1.92e-052153232092146
Pubmed

The mouse gene Ptprf encoding the leukocyte common antigen-related molecule LAR: cloning, characterization, and chromosomal localization.

PTPRD PTPRF

1.92e-05215327665159
Pubmed

Homophilic adhesion and CEACAM1-S regulate dimerization of CEACAM1-L and recruitment of SHP-2 and c-Src.

PTPN6 PTPN11

1.92e-052153219948503
Pubmed

FBXW7β loss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth.

FASN FBXW7

1.92e-052153237202390
Pubmed

Identification and characterization of leukocyte-associated Ig-like receptor-1 as a major anchor protein of tyrosine phosphatase SHP-1 in hematopoietic cells.

LAIR1 PTPN6

1.92e-052153210764762
Pubmed

Redox regulation of SH2-domain-containing protein tyrosine phosphatases by two backdoor cysteines.

PTPN6 PTPN11

1.92e-052153219166311
Pubmed

AMPK-dependent inhibitory phosphorylation of ACC is not essential for maintaining myocardial fatty acid oxidation.

ACACA ACACB

1.92e-052153225001074
Pubmed

Mice deficient in OX40 and CD30 signals lack memory antibody responses because of deficient CD4 T cell memory.

TNFRSF4 TNFRSF8

1.92e-052153215778343
Pubmed

Downregulation of platelet responsiveness upon contact with LDL by the protein-tyrosine phosphatases SHP-1 and SHP-2.

PTPN6 PTPN11

1.92e-052153219096001
Pubmed

Residue 259 is a key determinant of substrate specificity of protein-tyrosine phosphatases 1B and alpha.

PTPN1 PTPRA

1.92e-052153210748206
Pubmed

The subcellular localization of acetyl-CoA carboxylase 2.

ACACA ACACB

1.92e-052153210677481
Pubmed

Susceptibility of podocytes to palmitic acid is regulated by fatty acid oxidation and inversely depends on acetyl-CoA carboxylases 1 and 2.

ACACA ACACB

1.92e-052153224338821
Pubmed

PTPN1 Deficiency Modulates BMPR2 Signaling and Induces Endothelial Dysfunction in Pulmonary Arterial Hypertension.

PTPN1 BMPR2

1.92e-052153236672250
Pubmed

Sequence specificity of SHP-1 and SHP-2 Src homology 2 domains. Critical roles of residues beyond the pY+3 position.

PTPN6 PTPN11

1.92e-052153216702225
Pubmed

De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.

ACACA ACACB

1.92e-052153225282359
Pubmed

Global proteomic assessment of the classical protein-tyrosine phosphatome and "Redoxome".

PTPN11 PTPRD

1.92e-052153221884940
Pubmed

Acetyl-CoA carboxylase rewires cancer metabolism to allow cancer cells to survive inhibition of the Warburg effect by cetuximab.

ACACA ACACB

1.92e-052153227693630
Pubmed

Associations of a PTPN11 G/A polymorphism at intron 3 with Helicobactor pylori seropositivity, gastric atrophy and gastric cancer in Japanese.

PTPN1 PTPN11

1.92e-052153219589142
Pubmed

Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment.

DUSP9 DUSP16

1.92e-052153229880481
Pubmed

LAR tyrosine phosphatase receptor: proximal membrane alternative splicing is coordinated with regional expression and intraneuronal localization.

PTPRA PTPRF

1.92e-05215329748473
Pubmed

Hippocampal SH2-containing protein-tyrosine phosphatases are involved in extinction of contextual fear.

PTPN6 PTPN11

1.92e-052153220400923
Pubmed

Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue.

ACACA ACACB

1.92e-052153232215608
Pubmed

Protein tyrosine phosphatase alpha inhibits hypothalamic leptin receptor signaling and regulates body weight in vivo.

PTPRA PTPRE

1.92e-052153230615487
Pubmed

Activity and structure of human acetyl-CoA carboxylase targeted by a specific inhibitor.

ACACA ACACB

1.92e-052153229772612
Pubmed

Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin.

ACACA ACACB

1.92e-052153229976587
Pubmed

H-2Dd engagement of Ly49A leads directly to Ly49A phosphorylation and recruitment of SHP1.

PTPN6 PTPN11

1.92e-052153210457220
Pubmed

S-nitrosylation of endogenous protein tyrosine phosphatases in endothelial insulin signaling.

PTPN1 PTPN11

1.92e-052153227521458
Pubmed

Structure and regulation of acetyl-CoA carboxylase genes of metazoa.

ACACA ACACB

1.92e-052153215749055
Pubmed

Molecular cloning and expression of a cDNA encoding a protein tyrosine phosphatase from mouse brain.

PTPN1 PTPN11

1.92e-05215328955893
Pubmed

SHP1 and SHP2 inhibition enhances the pro-differentiative effect of phorbol esters: an alternative approach against acute myeloid leukemia.

PTPN6 PTPN11

1.92e-052153230764849
Pubmed

FBW7 increases drug sensitivity to cisplatin in human nasopharyngeal carcinoma by downregulating the expression of multidrug resistance-associated protein.

ABCC1 FBXW7

1.92e-052153225586348
Pubmed

Combination blockade of OX40L and CD30L inhibits allergen-driven memory TH2 cell reactivity and lung inflammation.

TNFRSF4 TNFRSF8

1.92e-052153233160971
Pubmed

AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis.

ACACA ACACB

1.92e-052153229433631
Pubmed

Significance of SHP-1 and SHP-2 expression in human papillomavirus infected Condyloma acuminatum and cervical cancer.

PTPN6 PTPN11

1.92e-052153218543080
InteractionPTPRE interactions

PTPRA PTPRB PTPRD PTPRE PTPRJ PTPRS HTT

7.04e-07691477int:PTPRE
InteractionPTPRM interactions

CNKSR1 CDC42BPA PTPN1 PTPN6 PTPRA PTPRF PTPRS

9.43e-07721477int:PTPRM
InteractionPTPN6 interactions

CNKSR1 LAIR1 DUSP22 JAK3 PTPN1 PTPN6 PTPN11 PTPRA MS4A2 PTPRF PTPRS SIGLEC11

9.62e-0727814712int:PTPN6
InteractionHRAS interactions

TRAF7 ABCC1 ANKS6 RAP1GDS1 CDC42BPA SLC26A2 PRXL2B TTC21A DUSP9 DUSP22 PDLIM4 RASGRP1 BMPR2 PTPRA PTPRF PTPRJ SLC20A2 PRSS50 FBXW7

1.42e-0672514719int:HRAS
InteractionSIGLEC11 interactions

PTPN6 PTPN11 SIGLEC11

1.51e-0641473int:SIGLEC11
InteractionGHR interactions

DUSP7 PTPN1 PTPN6 PTPN9 PTPN11 PTPRB

1.87e-06511476int:GHR
InteractionKCNE4 interactions

OBSL1 CNNM4 PTPRF PTPRS SLC27A2

9.09e-06391475int:KCNE4
InteractionPTPRG interactions

DUSP22 DUSP26 PTPRA PTPRB PTPRE PTPRJ PTPRS

9.86e-061021477int:PTPRG
InteractionPTPRS interactions

PTPN6 PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS

1.68e-051531478int:PTPRS
InteractionPTPN13 interactions

TEDC2 PDLIM4 PTPN6 PTPRA PTPRB PTPRE PTPRF PTPRJ PTPRS

1.79e-052021479int:PTPN13
InteractionLAIR1 interactions

LAIR1 PTPN6 PTPN11

2.07e-0581473int:LAIR1
InteractionMRAP2 interactions

LRP12 PTPN1 BMPR2 PTPRD PTPRF PTPRS

2.11e-05771476int:MRAP2
InteractionPTPRA interactions

ACACA PTPN6 PTPN11 PTPRA PTPRD PTPRE PTPRF PTPRS

2.77e-051641478int:PTPRA
InteractionPTPRQ interactions

PTPN6 PTPRA PTPRF PTPRS

3.05e-05251474int:PTPRQ
InteractionPTPRB interactions

DDX31 PTPRB PTPRE PTPRJ PTPRS

3.46e-05511475int:PTPRB
InteractionPTPN2 interactions

JAK3 PTPN1 PTPN6 PTPN11 PTPRB PTPRD PTPRE PTPRJ PTPRS

3.89e-052231479int:PTPN2
InteractionMAPK11 interactions

DUSP2 DUSP9 OBSL1 CPNE6 DUSP16

5.46e-05561475int:MAPK11
InteractionPPFIA3 interactions

CNKSR1 PTPRD PTPRF PTPRS HTT

5.95e-05571475int:PPFIA3
InteractionSPAG7 interactions

ACACA ACAT2 TERF2IP NLE1

7.34e-05311474int:SPAG7
InteractionOMG interactions

PTPRD PTPRF PTPRS

1.03e-04131473int:OMG
InteractionPTPN20 interactions

PTPN1 PTPN6 PTPRA

1.30e-04141473int:PTPN20
InteractionPTPRC interactions

JAK3 PTPN6 PTPRA PTPRE PTPRS

1.49e-04691475int:PTPRC
InteractionMPIG6B interactions

PTPN6 PTPN11

1.58e-0431472int:MPIG6B
InteractionMARCHF1 interactions

SLC26A2 BMPR2 PTPRA PTPRF PTPRS

1.59e-04701475int:MARCHF1
Cytoband2q11

DUSP2 CNNM4

3.30e-05315322q11
CytobandEnsembl 112 genes in cytogenetic band chr3p21

DUSP7 NCKIPSD SEMA3G STAB1 ATRIP PRSS50 PRSS42P

9.84e-053161537chr3p21
Cytoband6p25.3

HUS1B DUSP22

4.88e-041015326p25.3
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRA PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS

4.02e-11211167813
GeneFamilyProtein tyrosine phosphatases, non-receptor type

PTPN21 PTPN1 PTPN6 PTPN9 PTPN11

7.99e-08181165812
GeneFamilyMAP kinase phosphatases

DUSP2 DUSP7 DUSP9 DUSP16

5.13e-07111164895
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

MYLK FSTL4 OBSL1 PTPRD PTPRF PTPRS SIGLEC11 SIGLEC1

9.35e-061611168593
GeneFamilyAnkyrin repeat domain containing

SHANK1 ANKRD31 ACAP1 ANKS6 ACBD6 ARAP3 ANKAR ANKRD17 ACAP2

2.61e-052421169403
GeneFamilySolute carriers

SLC22A25 SLC26A2 SLC35G2 SLC7A14 SLC26A1 SLC7A4 SLC8B1 SLC20A2 SLC15A5 SLC27A2

2.30e-0439511610752
GeneFamilyWD repeat domain containing

TRAF7 NWD1 NBEAL1 WDR46 FBXW5 NLE1 WDFY1 FBXW7

2.88e-042621168362
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ACAP1 CNKSR1 TIAM2 PLEKHH1 ARAP3 PLEKHH2 ACAP2

3.68e-042061167682
GeneFamilyFibronectin type III domain containing

MYLK PTPRB PTPRD PTPRF PTPRJ PTPRS

5.82e-041601166555
GeneFamilyArfGAPs

ACAP1 ARAP3 ACAP2

1.22e-03331163395
GeneFamilyWD repeat domain containing|F-box and WD repeat domain containing

FBXW5 FBXW7

2.16e-03111162559
GeneFamilySterile alpha motif domain containing

SHANK1 CNKSR1 ANKS6 ARAP3

2.48e-03881164760
GeneFamilyATP binding cassette subfamily C

ABCC1 ABCC11

3.04e-03131162807
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

PTPN21 PLEKHH1 PLEKHH2

4.05e-035011631293
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

ACAP1 ACAP2

5.21e-031711621291
GeneFamilyAtypical dual specificity phosphatases

DUSP22 DUSP26

5.84e-03181162896
GeneFamilyProteases, serine

PRSS36 PRSS50 PRSS42P

7.73e-03631163738
ToppCellfacs-Heart-RV-24m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPA2 ACACA DUSP2 EXOSC5 UBASH3A PTPN6 TNFRSF8 AGBL1

1.19e-071671538f72c0ec1bb682c20bfaab726f9ee17a5a00cf0b1
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC1 DUSP2 LAIR1 SEMA3G PRSS36 PTPN6 FZD5 SIGLEC1

1.31e-07169153815a9183c838cc6384d7f5dfeae3d30602964c9b3
ToppCelldroplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DUSP2 LAIR1 TIAM2 PTPN6 PTPRE PTPRJ ST3GAL5 DUSP16

1.43e-07171153800739085fdbc4d64c9faacba2c2adeab580dd2b1
ToppCelldroplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DUSP2 LAIR1 TIAM2 PTPN6 PTPRE PTPRJ ST3GAL5 DUSP16

1.50e-0717215385f58ff6cac32546d07b2a49ed250b6c7aa417188
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRAF7 PDE2A ACACB JAK3 DUSP26 PTPRB ARAP3 FHOD1

1.56e-07173153866488d01e03264fb193285470901c9c4182fbae8
ToppCelldroplet-Lung-LUNG-1m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP2 LAIR1 TIAM2 PTPN6 PTPRE PTPRJ ST3GAL5 DUSP16

1.71e-071751538c8cfe0ac0c1ac447c626a623cc49692a0b177a1c
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP2 LAIR1 TIAM2 PTPN6 PTPRE PTPRJ ST3GAL5 DUSP16

1.71e-07175153861fbd8f685d3daad46449e4c0386a38886496566
ToppCellControl-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

ABCC1 ACAP1 RIPOR2 TNFRSF4 JAK3 RASGRP1 PTPRJ DUSP16

2.12e-07180153847036eee4c128fbb443d1fc767b4de5cced93f0e
ToppCellIPF-Lymphoid-T_Regulatory|IPF / Disease state, Lineage and Cell class

ABCC1 ACAP1 RIPOR2 TNFRSF4 JAK3 RASGRP1 PTPRJ DUSP16

2.61e-071851538221cbd09d94cc0947d0e3c1aa14716d17cb2068d
ToppCellIPF-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

ABCC1 ACAP1 RIPOR2 TNFRSF4 JAK3 RASGRP1 PTPRJ DUSP16

2.61e-07185153877fbecdab10bacc005b1c7e22ca414cfecef13c1
ToppCellEndothelial-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

RELN PDE2A PRXL2B TTC21A PTPN21 DNAJC6 TNFRSF4 PTPRB

2.95e-071881538ecb74d67314a43b5805b7f2a7bb9ff6c5a60200a
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A SEMA3G STAB1 BMPR2 PTPRB ARAP3 ADAMTS6 PPM1F

4.72e-0720015382e47888e041ec3d265425d1df97b6665c6da889c
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A SEMA3G STAB1 BMPR2 PTPRB ARAP3 ADAMTS6 PPM1F

4.72e-07200153850fa0f8a3e490d5941b34e66a10158eba6c909d4
ToppCell368C-Lymphocytic-NK_cells|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CDC42BPA TEDC2 CYP26A1 PRSS36 PTPRD PTPRE XCL2

8.97e-07150153717b3ac5ddc47b9cba0a27b268d63a6e491b2b111
ToppCellfacs-Heart-RV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPA2 ACACA EXOSC5 PTPN6 CPNE6 TNFRSF8 AGBL1

1.77e-06166153716d42eda958b2a6f9d598e9b4b967505dee426ef
ToppCelldroplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DUSP2 LAIR1 PTPN1 PTPN6 PTPRE PTPRJ DUSP16

1.77e-0616615371a3a15d1fc76bb91d832cdc6e3da0a6140b94b75
ToppCellfacs-Heart-RV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPA2 ACACA EXOSC5 PTPN6 CPNE6 TNFRSF8 AGBL1

1.77e-06166153708d7db4ff1c9c9cea3a36a87b8690838e79d4e0e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAIR1 TIAM2 PTPN6 PTPRE PTPRJ ST3GAL5 DUSP16

1.91e-0616815374b5be7c6662eceddf90a65015f12908278d1664e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAIR1 TIAM2 PTPN6 PTPRE PTPRJ ST3GAL5 DUSP16

1.91e-061681537689c41f6e9f65381570991cc311cba49a57ec955
ToppCelldroplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAIR1 TIAM2 PTPN6 PTPRE PTPRJ ST3GAL5 DUSP16

1.99e-061691537b059304543876f514d5c7214f1f0a2da00f10a67
ToppCellControl-T_cells-Tregs|Control / group, cell type (main and fine annotations)

ACAP1 RIPOR2 UBASH3A TNFRSF4 JAK3 RASGRP1 DUSP16

1.99e-061691537e1e0983f31ec81b3fad5f9c6140d17f03f81a5dc
ToppCelldroplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAIR1 TIAM2 PTPN6 PTPRE PTPRJ ST3GAL5 DUSP16

1.99e-061691537945f737984c4de70a4e9c214053b005358053dd5
ToppCelldroplet-Lung-nan-21m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAIR1 TIAM2 PTPN6 PTPRE PTPRJ ST3GAL5 DUSP16

2.24e-06172153751bea97564a33f0060c546c9be4bf8bf8f1660f6
ToppCelldroplet-Lung-nan-21m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAIR1 TIAM2 PTPN6 PTPRE PTPRJ ST3GAL5 DUSP16

2.24e-061721537be4dd4ba8d7a651677c797c25fd75f14e627415a
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE2A DUSP2 SEMA3G BMPR2 PTPRB ARAP3 PPM1F

2.42e-06174153740bb87d219aafab0357ab0d797efd38085fc0312
ToppCellP15-Endothelial-lymphatic_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RELN PDE2A DUSP2 PDLIM4 STAB1 PTPRE ANKAR

2.51e-061751537a00c6fa9b33640710dd05a3799031147196f0986
ToppCellP15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RELN PDE2A DUSP2 PDLIM4 STAB1 PTPRE ANKAR

2.51e-06175153784d252f3e432231687613299bbea14978bb4b06b
ToppCellfacs-SCAT-Fat-24m-Lymphocytic-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 RIPOR2 DUSP2 UBASH3A RASGRP1 TNFRSF8 AGBL1

3.02e-06180153786cdb1652f1736c38b501f07cf40ce99134cf597
ToppCellIPF-Lymphoid-ILC_B|World / Disease state, Lineage and Cell class

ABCC1 ACAP1 RIPOR2 DUSP2 CYP26A1 TNFRSF4 XCL2

3.02e-061801537a4de9f67a7ab4b3c17247139fc584e13678411b4
ToppCellfacs-SCAT-Fat-24m-Lymphocytic|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 RIPOR2 DUSP2 UBASH3A RASGRP1 TNFRSF8 AGBL1

3.02e-061801537115ce9f048f933704a19759948dcc933245e63c4
ToppCellIPF-Lymphoid-ILC_B|IPF / Disease state, Lineage and Cell class

ABCC1 ACAP1 RIPOR2 DUSP2 CYP26A1 TNFRSF4 XCL2

3.02e-061801537b2fde7cd140a3ede8cac2d06f1f72eb438def82e
ToppCellCOVID-19-T_cells-Tregs|COVID-19 / group, cell type (main and fine annotations)

ACAP1 RIPOR2 TNFRSF4 JAK3 RASGRP1 PTPRJ DUSP16

3.14e-061811537534659cf754326c6a73c0daa30e9d610612a0292
ToppCellPBMC-Control-Hematopoietic-HSPC-HSPC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CDC42BPA OBSL1 MS4A2 NYNRIN CRISPLD1 SLC27A2 TLCD5

3.25e-0618215376497eeafb2b137e70261ec0314782831892a940d
ToppCellControl-Hematopoietic_SC-HSPC|Control / Disease group, lineage and cell class

CDC42BPA OBSL1 MS4A2 NYNRIN CRISPLD1 SLC27A2 TLCD5

3.25e-06182153714e347c0e6444410f1948851407bb18c706569f4
ToppCellControl-Hematopoietic_SC|Control / Disease group, lineage and cell class

CDC42BPA OBSL1 MS4A2 NYNRIN CRISPLD1 SLC27A2 TLCD5

3.25e-06182153743243c6bae2ac7fa3fd1f193a17f61ee4d938ea9
ToppCellPBMC-Control-Hematopoietic-HSPC-HSPC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CDC42BPA OBSL1 MS4A2 NYNRIN CRISPLD1 SLC27A2 TLCD5

3.25e-061821537d0ebf2f0d5370458ab81485a0017c311077133d5
ToppCellPBMC-Control-Hematopoietic-HSPC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CDC42BPA OBSL1 MS4A2 NYNRIN CRISPLD1 SLC27A2 TLCD5

3.25e-061821537918286422b3eab32d962b49aa07b1b9512e51d9d
ToppCellPBMC-Control-Hematopoietic-HSPC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CDC42BPA OBSL1 MS4A2 NYNRIN CRISPLD1 SLC27A2 TLCD5

3.25e-061821537bd1626261803324084fafca2f6665b50854e7fae
ToppCellhealthy_donor-Myeloid-Monocytic-SC_&_Eosinophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

CDC42BPA OBSL1 MS4A2 NYNRIN CRISPLD1 SLC27A2 TLCD5

3.25e-0618215376bd6c32c48fecd6d03ac8a09e405b3b99bdc12ae
ToppCellPBMC-Control-Hematopoietic-HSPC-HSPC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CDC42BPA OBSL1 MS4A2 NYNRIN CRISPLD1 SLC27A2 TLCD5

3.25e-0618215372a6d1246bfb5899a0861c7f2f8fb9b43b0df8acc
ToppCellControl-Lymphoid-T_Regulatory|Control / Disease state, Lineage and Cell class

ABCC1 ACAP1 RIPOR2 TNFRSF4 JAK3 RASGRP1 DUSP16

3.25e-06182153731bb838cc2900f3c9da9f835d79d557a08abb928
ToppCellPBMC-Control-Hematopoietic-HSPC-HSPC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CDC42BPA OBSL1 MS4A2 NYNRIN CRISPLD1 SLC27A2 TLCD5

3.25e-0618215370d9b8c900da8cbae9cde72aecd4026b1ac2bbd67
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3|lymph-node_spleen / Manually curated celltypes from each tissue

SHANK1 CYP26A1 TNFRSF4 PTPRD XCL2 APOL4 TLCD5

3.50e-061841537479e60f76c191253e23699c9dd7ef7efc08c59ad
ToppCellCOVID-19_Moderate-HSPC|World / disease group, cell group and cell class

CDC42BPA OBSL1 PTPRD MS4A2 NYNRIN CRISPLD1 SLC27A2

3.50e-061841537ccc93babe1fcdeb66b78e1d8414357877a7c45bd
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEMA3G STAB1 CNNM4 SLC8B1 PTPRB ATRIP CRISPLD1

3.62e-06185153787151ab95530e70d61328b336518df58db584acb
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-Treg|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCC1 ACAP1 TNFRSF4 JAK3 RASGRP1 PTPRJ DUSP16

3.62e-061851537a86a3a1a187a4d8d7762bc6d3dcb22c982178d22
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN PDE2A ACACB STAB1 PTPRB ARAP3 PPM1F

3.62e-06185153759acaf025353405948dc34ccccf37ec5c08ea903
ToppCell15-Distal-Immune-Hematopoietic,_Natural_Killer_Cell|Distal / Age, Tissue, Lineage and Cell class

ADGRG5 ACAP1 RIPOR2 LAIR1 JAK3 PTPN6 XCL2

4.17e-061891537281a7ccb18edf542a7756f2f90b20594436097f9
ToppCellsystemic_lupus_erythematosus-managed-Hematopoietic-progenitor_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

OBSL1 PTPRD MS4A2 NYNRIN CRISPLD1 SLC27A2 TLCD5

4.17e-0618915376687a93ac8540ece5fd762f6f77c1f25f159195b
ToppCellCOVID-19-Heart-T_cell|Heart / Disease (COVID-19 only), tissue and cell type

ADGRG5 ACAP1 RIPOR2 FSTL4 CSMD3 RASGRP1 AGBL1

4.32e-061901537e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCellmetastatic_Lymph_Node-T/NK_cells-Treg|metastatic_Lymph_Node / Location, Cell class and cell subclass

ACAP1 TERF2IP TNFRSF4 RASGRP1 TNFRSF8 DUSP16 SOD1

4.32e-0619015370523f1039b39a45a23f2f4444e5b47ed581fc4bb
ToppCellControl-Lymphoid-T|Control / Disease state, Lineage and Cell class

ABCC1 ACAP1 RIPOR2 JAK3 RASGRP1 DUSP16 NDUFAF6

4.79e-061931537af928046ccd1ca874be1534aef6ca7f27d90bc46
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG5 ACAP1 DUSP2 MRPL10 TERF2IP ADAMTS6 XCL2

4.95e-06194153764535db0420e53e4d777d2333b5051e63e8a3373
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A SEMA3G BMPR2 PTPRB ARAP3 PTPRE ADAMTS6

5.30e-0619615378ad8efb631164b46f0c082572270188e5ead20bf
ToppCellBronchial-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-ILC|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRG5 ACAP1 DUSP2 CSMD3 TNFRSF4 XCL2 HSD17B1

5.30e-0619615371cc2b11764584129703ec61965e8ec4e051464e7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN PDE2A SEMA3G PTPRB ARAP3 PTPRE ADAMTS6

5.30e-061961537145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCell(1)_T_cells-(1)_T_CD8_CytT|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

ADGRG5 DUSP2 LAIR1 GK5 PTPN6 ADAMTS6 XCL2

5.30e-0619615373a4ba9ca84ce6b35038765da8c55812587b58bc2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A SEMA3G BMPR2 PTPRB ARAP3 PTPRE ADAMTS6

5.30e-0619615379606ea7e42f707e69ea891b3521037613b9675f5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN PDE2A SEMA3G PTPRB ARAP3 PTPRE ADAMTS6

5.30e-061961537d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCellParenchyma_Control_(B.)-Immune-TX-T_cells|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

ACAP1 DUSP2 UBASH3A TNFRSF4 JAK3 RASGRP1 XCL2

5.48e-0619715373712eaa1d2ed200e0b0fdb2886f4cdf641fd2cdc
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ACAP1 DUSP2 MRPL10 TERF2IP JAK3 RASGRP1 SOD1

5.48e-061971537ef2d1f56acd0be43e69bba7f73f6909ba87f1cb3
ToppCellLung_Parenchyma-Control-Lymphocyte-T/NK|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ACAP1 DUSP2 UBASH3A TNFRSF4 JAK3 RASGRP1 XCL2

5.48e-061971537185e9a6bd9894a050604a1af66c2fc39cf1f8d7a
ToppCellLung_Parenchyma-Control-Lymphocyte-T/NK-Other_T-T_cells|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ACAP1 DUSP2 UBASH3A TNFRSF4 JAK3 RASGRP1 XCL2

5.48e-0619715377effa80fa97a97906a9e8e8d00513bebfef0f980
ToppCellLung_Parenchyma-Control-Lymphocyte-T/NK-Other_T-T_cells-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ACAP1 DUSP2 UBASH3A TNFRSF4 JAK3 RASGRP1 XCL2

5.48e-061971537af96ef0dbf89d4a2b78f48a1e1182b719025d67c
ToppCellLung_Parenchyma-Control-Lymphocyte-T/NK-Other_T|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ACAP1 DUSP2 UBASH3A TNFRSF4 JAK3 RASGRP1 XCL2

5.48e-0619715376153f14a457c0b8452729aa301e5486a539e9cba
ToppCell5'-Adult-Distal_Rectal-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE2A SLC35G2 SEMA3G PDLIM4 BMPR2 PTPRB TNFRSF8

5.66e-0619815378d6b0b9da7c1e64155cbcbb04ad38d129a29030c
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC35G2 SEMA3G PDLIM4 BMPR2 PTPRB ARAP3 TNFRSF8

5.66e-06198153758508a8df2714d769f137794c29441a7bd38b350
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ACAP1 DUSP2 MRPL10 TERF2IP JAK3 RASGRP1 SOD1

5.66e-06198153733a3b279c9ff3b762e52d060dae062167ca2239b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A SEMA3G STAB1 BMPR2 PTPRB ARAP3 ADAMTS6

5.85e-061991537f35e9c05d0a0339ff691b38564da7aad8e9218aa
ToppCellControl-Control-Lymphocyte-T/NK-Treg|Control / Disease, condition lineage and cell class

ACAP1 SEMA3G UBASH3A TNFRSF4 RASGRP1 DUSP16 SOD1

5.85e-0619915376b7eb14bf03aa05f2d4ac4f5dd1ccf41a7e47bd1
ToppCellControl-Control-Others-HSPC|Control / Disease, condition lineage and cell class

CDC42BPA OBSL1 DNAJC6 MS4A2 NYNRIN SLC27A2 TLCD5

5.85e-061991537b71169be0d916b2ed139a3122d78bb154c71edb4
ToppCellCOVID-19-COVID-19_Mild-Others-HSPC|COVID-19_Mild / Disease, condition lineage and cell class

CDC42BPA OBSL1 DNAJC6 MS4A2 NYNRIN SLC27A2 TLCD5

5.85e-0619915370230103c37ae3aff58240739b89f2c36b1e39a69
ToppCellPBMC-Severe-cDC_3|Severe / Compartment, Disease Groups and Clusters

ADGRG5 MYLK OBSL1 ABCC11 DUSP16 PADI6

1.44e-0515215361a3f8ed476aa9a39742b4684be2c704669e4a3d0
ToppCellfacs-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DUSP2 LAIR1 TIAM2 PTPRE PTPRJ DUSP16

1.80e-051581536121d63b8e2e37107467b170e5b2c798a7dbf6325
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACA TEDC2 DUSP2 PRSS36 TIAM2 ALG13

1.80e-0515815361d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 HUS1B DUSP2 UBASH3A PTPN6 MS4A2

1.93e-05160153697c899df1b57fd2bd1867e02bfedf1920c00ad17
ToppCellfacs-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DUSP2 LAIR1 TIAM2 PTPRE PTPRJ DUSP16

1.93e-051601536bc4a93dc5f37829799c37877e751ff3bc122e4ab
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RIPOR2 RAPSN LAIR1 PDLIM4 STAB1 PTPRJ

1.93e-05160153618954241e11309ecb0f3ca87897eadcb20dc8eca
ToppCellfacs-Lung-nan-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP2 LAIR1 TIAM2 PTPRE PTPRJ DUSP16

2.07e-0516215363fd6aaf0fbaffc7ab38aa25e46c37ef511e1e704
ToppCellfacs-Lung-nan-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP2 LAIR1 TIAM2 PTPRE PTPRJ DUSP16

2.07e-0516215368134f73eb76693f4f1845f643042fdc1e81c274c
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SEMA3G TNFRSF4 CEMIP TNFRSF8 DUSP16 TLCD5

2.14e-051631536bca9abd02ffb2a90c8386a59f5e25126ae7b6acd
ToppCelldroplet-Lung-3m-Hematologic-myeloid-non-classical_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAIR1 TIAM2 PTPN6 PTPRE PTPRJ DUSP16

2.14e-051631536f6c8db5963ee1f8e0c2996f1aeecd58c00e9b099
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|343B / Donor, Lineage, Cell class and subclass (all cells)

ADGRG5 ACAP1 DUSP2 BCO2 XCL2 DDX28

2.14e-0516315368a4931c9fdaedcf6c319157821d3556cd25fc9e5
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE2A RAP1GDS1 CTRC EXOSC5 RPUSD3 XCL2

2.14e-051631536e4077e587895c85bc806be05ff5d451088e39468
ToppCellfacs-Lung-3m-Hematologic-myeloid-non-classical_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAIR1 TIAM2 PTPN6 PTPRE PTPRJ DUSP16

2.14e-051631536bbbc3f0ce2616d07136f69ce682ba1d3790711d9
ToppCellfacs-Lung-3m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAIR1 TIAM2 PTPN6 PTPRE PTPRJ DUSP16

2.22e-05164153611dfd84f5fb90de330858e1e852848832734e004
ToppCelldroplet-Lung-3m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAIR1 TIAM2 PTPN6 PTPRE PTPRJ DUSP16

2.22e-051641536ea2897942ad72fba900c7ab354d6a9e203bf0e4a
ToppCell3'_v3-Lung-Lymphocytic_Invariant-Inducer-like-ILC3|Lung / Manually curated celltypes from each tissue

SHANK1 CYP26A1 FSTL4 TNFRSF4 XCL2 TLCD5

2.46e-0516715360614d077b47a87f726068615548d0b0a216627be
ToppCelldroplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DUSP2 LAIR1 TIAM2 PTPRE PTPRJ DUSP16

2.54e-051681536d823979335ac6b5d1f062ebb741c759d2f919dbf
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like|GI_small-bowel / Manually curated celltypes from each tissue

SHANK1 CYP26A1 FSTL4 TNFRSF4 APOL4 CRISPLD1

2.54e-051681536d02eba7ece17edcdd47fd6b784c93910ce61090f
ToppCelldroplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DUSP2 LAIR1 TIAM2 PTPRE PTPRJ DUSP16

2.54e-051681536f377ff4c066a9857ad14d245e56325ad220e22e1
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

SHANK1 CYP26A1 FSTL4 TNFRSF4 APOL4 CRISPLD1

2.72e-05170153697df5ffb328196c46568975d2d97722bcc753bf5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 HUS1B DUSP2 UBASH3A PTPN6 MS4A2

2.72e-051701536c4f00c1acde1d3b521101e469101d10fd257653e
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SHANK1 CYP26A1 TNFRSF4 PTPRD CRISPLD1 TLCD5

2.72e-0517015366c65ddb496030bb479ef346cc37a9d4dfa6b824f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 HUS1B DUSP2 UBASH3A PTPN6 MS4A2

2.72e-051701536d3c1edaf0190d8927578043c372dba7477e75e14
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC21A AGPAT2 LAIR1 GK5 SLC8B1 HSD17B1

2.81e-051711536fea6ef6bbfebea2dd0f0360c7db7a5e858f15958
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC21A AGPAT2 LAIR1 GK5 SLC8B1 HSD17B1

2.81e-051711536f15594fd4d709920733de9376a391dedc62b65de
ToppCellnormal_Lung-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

LRP12 PDLIM4 PTPN9 ATRIP DUSP16 XCL2

2.81e-051711536f49dfe11ae66d82125b577c48345a13683d7bb7b
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG5 CTRC BCO2 ST3GAL5 PJVK PRSS42P

2.90e-051721536a5344760b10ecdc0101f78b93b8fc0f8107068c5
ToppCellsevere_COVID-19-HSPC|severe_COVID-19 / disease group, cell group and cell class (v2)

OBSL1 ABCC11 PTPRD MS4A2 NYNRIN TLCD5

3.09e-0517415366d35bacf073537b272ff821e604c899fb9ce6a7c
Drug2-(oxalylamino)benzoic acid

PTPN1 PTPN6 PTPRA PTPRB PTPRE PTPRF

5.81e-1371536ctd:C405943
Drugp-nitrophenyl phosphate

DUSP2 DUSP7 DUSP9 DUSP22 PTPN1 DUSP26 PTPN6 PTPRB PTPRD MS4A2 PTPRE DUSP16

8.06e-0919415312CID000000378
Drugsalicylideneaniline

PTPN1 PTPN6 PTPN9 PTPN11

9.75e-0951534ctd:C510217
DrugSchiff Bases

PTPN1 PTPN6 PTPN9 PTPN11

9.75e-0951534ctd:D012545
Drugoxovanadium IV

PTPN1 PTPN6 PTPN9 PTPN11

9.75e-0951534ctd:C075743
Drughydroxyl radicals

ABCC1 PDE2A IMPA2 SLC26A2 DUSP2 CYP26A1 DUSP7 DUSP9 AMDHD2 DAO PTPN21 PTPN1 DUSP26 PTPN6 FASN PTPN9 PTPN11 PTPRB PTPRD PTPRE PTPRF PTPRJ PTPRS PPM1F DUSP16 PADI6 SOD1 SLC27A2 ATP5F1C

2.01e-08134115329CID000000961
Druganthranilic acid

PTPN1 PTPN6 PTPN9 PTPN11

9.31e-07121534ctd:C031385
DrugNaphthylazoxine 6S

PTPN1 PTPN6 PTPN11 PTPRJ

3.35e-06161534CID005351905
Diseasemuscular disease (implicated_via_orthology)

ACACA ACACB FASN NMT1

3.03e-0951484DOID:0080000 (implicated_via_orthology)
DiseaseHbA1c measurement

ABCC1 FOXN2 RIPOR2 RAPSN ACACB CLASP1 DUSP9 DHRS13 RASGRP1 PTPN11 ATRIP PTPRJ SLC20A2 NDUFAF6 PLEKHH2

1.67e-0667514815EFO_0004541
Diseaseazoospermia (implicated_via_orthology)

CDC42BPA PTPRD PTPRF PTPRS

9.75e-06271484DOID:14227 (implicated_via_orthology)
DiseaseMalignant tumor of mediastinum

JAK3 PTPN1

2.50e-0521482C0153504
DiseaseMediastinal Neoplasms

JAK3 PTPN1

2.50e-0521482C0025063
DiseaseNoonan syndrome 1 (implicated_via_orthology)

PTPN6 PTPN11

2.50e-0521482DOID:0060578 (implicated_via_orthology)
DiseaseHodgkin Disease

RELN PTPN1 TNFRSF8

1.78e-04221483C0019829
Diseasejuvenile myelomonocytic leukemia (implicated_via_orthology)

PTPN6 PTPN11

2.47e-0451482DOID:0050458 (implicated_via_orthology)
Diseaselymphocyte count

ABCC1 ACAP1 RIPOR2 NWD1 RAPSN ACACA LAIR1 SLC35G2 UBASH3A DUSP22 PDLIM4 PTPN1 PTPRJ ST3GAL5 NDUFAF6 SIGLEC1 ACAP2 HTT

4.04e-04146414818EFO_0004587
Diseaselevel of Sphingomyelin (d36:2) in blood serum

RAPSN ANKRD17

5.16e-0471482OBA_2045177
Diseasejuvenile myelomonocytic leukemia (is_implicated_in)

JAK3 PTPN11

5.16e-0471482DOID:0050458 (is_implicated_in)
Diseaseglucose measurement

RAPSN VPS13C DUSP9 PTPRJ NDUFAF6 KDM4A PLEKHH2 NMT1

6.93e-043801488EFO_0004468
Diseasemean reticulocyte volume

ADGRG5 ABCC1 RIPOR2 RAPSN CLASP1 NLRX1 PTPN1 PTPN11 PTPRA PTPRF PTPRJ NYNRIN

7.27e-0479914812EFO_0010701
DiseaseColorectal Carcinoma

SHANK1 ABCC1 ACAP1 ACACA AMDHD2 CSMD3 ARAP3 PTPRD PTPRS PPM1F FBXW7

8.61e-0470214811C0009402
Diseasemean arterial pressure

CYP26A1 PTPN11 ARAP3 PTPRD PTPRJ PRSS42P NDUFAF6 NMT1 TLCD5

9.71e-044991489EFO_0006340
Diseaseintraocular pressure measurement

LRP12 RELN RAPSN ISOC1 OR4P4 PTPRJ ADAMTS6 NDUFAF6 TLCD5

1.11e-035091489EFO_0004695
Diseasephosphatidylcholine 32:0 measurement

RAPSN PTPRD

1.33e-03111482EFO_0010372
Diseasedyslexia

PTPN21 PTPRA HEATR5B NMT1 HTT

1.38e-031621485EFO_0005424
DiseaseDisease Exacerbation

ABCC1 WDR46 ABCC11 EXOSC5 PTPRF

1.50e-031651485C0235874
DiseaseLeigh disease (implicated_via_orthology)

SURF1 NDUFAF6

1.60e-03121482DOID:3652 (implicated_via_orthology)
DiseaseB-Cell Lymphomas

JAK3 PTPN1

1.60e-03121482C0079731
DiseaseHodgkin lymphoma, lymphocyte depletion

PTPN1 TNFRSF8

1.88e-03131482C0152267
DiseaseMixed Cellularity Hodgkin Lymphoma

PTPN1 TNFRSF8

1.88e-03131482C0152266
DiseaseLymphocyte Rich Classical Hodgkin Lymphoma

PTPN1 TNFRSF8

1.88e-03131482C1266194
DiseaseAdult Hodgkin Lymphoma

PTPN1 TNFRSF8

1.88e-03131482C0220597
Diseaselevel of Sphingomyelin (d34:2) in blood serum

RAPSN ANKRD17

1.88e-03131482OBA_2045174
DiseaseNodular Lymphocyte Predominant Hodgkin Lymphoma

PTPN1 TNFRSF8

1.88e-03131482C1334968
Diseaseurate measurement

RIPOR2 RAPSN STAB1 CEMIP BMPR2 PTPN9 PTPN11 PTPRF SLC20A2 NDUFAF6 HEATR5B TECPR1

1.90e-0389514812EFO_0004531
Diseaseinflammatory bowel disease

LRP12 RAPSN PRXL2B UBASH3A DUSP22 PDLIM4 RASGRP1 DUSP16

2.00e-034491488EFO_0003767
Diseaseamyotrophic lateral sclerosis, age at onset

PTPRF KDM4A

2.51e-03151482EFO_0004847, MONDO_0004976
Diseaseecosanoids measurement

ABCC1 RAPSN SLC27A2

2.68e-03551483EFO_0020044
Diseasephosphatidylcholine 38:6 measurement

RAPSN PTPRA

2.86e-03161482EFO_0010388
Diseasesuccinylcarnitine measurement

ABCC1 PTPRA

2.86e-03161482EFO_0020020
DiseaseMalignant neoplasm of breast

ABCC1 ACAP1 PDE2A CNNM4 FASN BMPR2 ARAP3 PTPRD PPM1F SURF1 POP1 NLE1 FBXW7

3.02e-03107414813C0006142
DiseaseHuntington Disease

RELN HTT

3.23e-03171482C0020179
Diseaseloneliness measurement

RAPSN PTPRD PTPRJ AGBL1

3.58e-031241484EFO_0007865
Diseasephosphatidylcholine 36:4 measurement

RIPOR2 RAPSN

3.63e-03181482EFO_0010382
Diseaselevel of Phosphatidylcholine (16:0_22:5) in blood serum

RAPSN AGPAT2

3.63e-03181482OBA_2045079
Diseasealcohol consumption measurement

FOXN2 RELN RAPSN DDX31 ACACA ACACB UBASH3A CSMD3 GK5 PTPRB PTPRJ SLC15A5 AGBL1 HTT

3.98e-03124214814EFO_0007878
Diseaseesterified cholesterol measurement

ANKRD31 RAPSN NYNRIN ANKRD17

4.01e-031281484EFO_0008589
Diseaseprion disease

ATRIP POP1

4.04e-03191482EFO_0004720
DiseaseChronic myeloproliferative disorder

JAK3 ATRIP

4.04e-03191482C1292778
Diseasebipolar disorder (is_marker_for)

RELN IMPA2

4.04e-03191482DOID:3312 (is_marker_for)
Diseaselevel of Sphingomyelin (d38:2) in blood serum

RAPSN ANKRD17

4.04e-03191482OBA_2045179
DiseaseJuvenile Myelomonocytic Leukemia

JAK3 PTPN11

4.04e-03191482C0349639
Diseaseleukemia (implicated_via_orthology)

PTPN6 PTPN11

4.04e-03191482DOID:1240 (implicated_via_orthology)
Diseasewhite matter hyperintensity measurement

ABCC1 NBEAL1 ADRA1D PTPRD ST3GAL5 NMT1

4.29e-033021486EFO_0005665
Diseasenon-alcoholic fatty liver disease (biomarker_via_orthology)

ACACA ACACB FASN

4.30e-03651483DOID:0080208 (biomarker_via_orthology)
Diseasebitter alcoholic beverage consumption measurement

RELN ADRA1D PTPRD AGBL1

4.59e-031331484EFO_0010092
Diseasehemoglobin A1 measurement

ABCC1 RAPSN NLRX1 DUSP9 RASGRP1 PTPN9 PTPRA NDUFAF6

4.85e-035201488EFO_0007629
DiseaseThyroid preparation use measurement

RAPSN UBASH3A TNFRSF4 RASGRP1 PTPN11

4.86e-032171485EFO_0009933
Diseasegestational age, birth measurement

RAPSN PTPRD

4.93e-03211482EFO_0005112, EFO_0006921

Protein segments in the cluster

PeptideGeneStartEntry
GTVVCSVLDISHIEG

MS4A2

76

Q01362
LVISHAGAGSCLETL

ALG13

76

Q9NP73
CISFVTQHGLRLEGV

ARAP3

926

Q8WWN8
LIGNSALTCLHGVSR

CSMD3

2256

Q7Z407
VHRGCVIANVVSGST

APOL4

136

Q9BPW4
AVIGGLCHSSISRLK

RASGRP1

296

O95267
GVVCGALHVADVSLR

ACACA

631

Q13085
GVTLCIQCSGIHRSL

ACAP1

436

Q15027
TIGCVLVFGNSTLHL

SLC7A4

491

O43246
ITLCIECSGIHRSLG

ACAP2

431

Q15057
GCKTVSLVLQRHTTG

ACBD6

266

Q9BR61
TVLSLACAGGHLAVV

ANKRD17

666

O75179
LGETIHGVQVICSIA

BCO2

261

Q9BYV7
FSRCVTVHGSNGLLI

CEMIP

586

Q8WUJ3
VALSNCVGLHGVIAT

ADAMTS6

146

Q9UKP5
LCRVKTGRSTVHLGS

AGBL1

416

Q96MI9
TLGASRVELRVSCHG

CPNE6

16

O95741
RVHLILSACSGALGV

NWD1

461

Q149M9
VGAVFGLTTCISAHV

NDUFA11

66

Q86Y39
SDICIIGEHIVTGSI

NBEAL1

2591

Q6ZS30
VLQVSCGRAHSLVLT

RCC1L

176

Q96I51
GRFRVLGCLVTAHSE

RAPSN

41

Q13702
GLHVDGVAVTLTSCC

JAK3

461

P52333
IVVHCSAGIGRTGTF

PTPN9

511

P43378
IGAGVIGLSTALCIH

DAO

6

P14920
VTISLVTCRAIGIGA

ACACB

1926

O00763
IRAVGSICIGVAHTS

ANKAR

1056

Q7Z5J8
VETICHRKEGGSSLI

ANKRD31

301

Q8N7Z5
AVLEVTVSRSGGHVC

OBSL1

1826

O75147
QCFTIHGSGRVLIDV

PADI6

46

Q6TGC4
VVHCSAGVGRTGTFI

PTPRB

1901

P23467
IVVHCSAGVGRTGTF

PTPRE

331

P23469
LVHCSAGVGRTGTFI

PTPRJ

1236

Q12913
VVVHCSAGIGRSGTF

PTPN1

211

P18031
GVRSVVLFGVETHVC

ISOC1

201

Q96CN7
LDCGIRGTFSLVIHA

MYLK

81

Q15746
LVHCVVGVSRSATLV

DUSP13

126

Q6B8I1
GLGLTVSLLSHCLVA

GPR88

121

Q9GZN0
TRVITAAVIGSLICG

LRP12

491

Q9Y561
HCGVRVVSSRKLVGF

NMT1

211

P30419
GTVIPLGSHVTFVCR

LAIR1

36

Q6GTX8
GRVLVHCQAGISRSA

DUSP2

251

Q05923
LISGNLHRIGDITSC

FBXW5

201

Q969U6
TIIIVCCTGGFIHSA

OR4P4

141

Q8NGL7
GAVAAVILVHCGQLS

PDE2A

156

O00408
GIIIHTAGRTCNISD

PGLYRP4

236

Q96LB8
HIGKAQGIVTCLRAT

NDUFAF6

206

Q330K2
GCTVLVIAHRVTTVL

ABCC11

1326

Q96J66
SLLRGRHVVCAAETG

DDX28

161

Q9NUL7
RHVVCAAETGSGKTL

DDX28

166

Q9NUL7
VLVHCLAGVSRSVTV

DUSP9

286

Q99956
LSCRAQGQTGVLTVH

KDM4A

531

O75164
TCEAVVLGTLHPRTS

EXOSC5

101

Q9NQT4
VVHCSAGIGRTGTFI

PTPN11

456

Q06124
VKCTVVAAVLGSGRH

NLRX1

711

Q86UT6
IGRTARIGCHGSSLL

DDX31

616

Q9H8H2
VRVIGSSTLALCHLA

IMPA2

201

O14732
QGHIELSASCSILRG

PLEKHH2

746

Q8IVE3
ALHFSGGCSRLLVTV

RELN

2551

P78509
ISVHCSAGVGRTGVF

PTPRS

1876

Q13332
VHCSAGVGRTGVVIL

PTPN21

1106

Q16825
TLHCSRTLLGFVTQG

POP1

956

Q99575
LAATHCVLRPGSTTV

PRSS36

626

Q5K4E3
LVRLVVGHASVACSR

FZD5

286

Q13467
CLEGIHLSQSGAVLT

HTT

1976

P42858
HQCLGRCLGAIITTV

HEATR5B

996

Q9P2D3
IGTRLHAAVAIACVV

TMEM167B

51

Q9NRX6
RHTCGGTLIASNFVL

CTRC

56

Q99895
LSSICRAAVHAGVVR

CRISPLD1

441

Q9H336
VLITGCSSGIGLHLA

HSD17B1

6

P14061
CSSGIGLHLAVRLAS

HSD17B1

11

P14061
LVHCLAGISRSATIA

DUSP16

241

Q9BY84
TVGLSTVLTCAVHGD

FSTL4

261

Q6MZW2
GIHVVSGSLDTSIRV

FBXW7

551

Q969H0
GGAQIVIDHLRSLCS

RAP1GDS1

131

P52306
VVHCLDGRAASSILV

DNAJC6

161

O75061
IGESRISHENGTILC

BMPR2

46

Q13873
GVLVHCLAGISRSVT

DUSP7

326

Q16829
SVLTVASRGGHLGVV

ANKS6

146

Q68DC2
VHCLAGVSRSVTLVI

DUSP22

86

Q9NRW4
GCLELFIHVSGTVAR

HUS1B

11

Q8NHY5
HLAGIRTCLGSLIST

FOXN2

406

P32314
VLGLDVGSSVIRCHV

GK5

21

Q6ZS86
VSSDRGLCGAIHSSI

ATP5F1C

96

P36542
VRTILGSGCLSNLHD

CYP26A1

116

O43174
VCHSGAVVSLLLSGV

ATRIP

486

Q8WXE1
FVHSEGLSCLIRVGA

FHOD1

156

Q9Y613
AIALSLGCRVFTTVG

FASN

1686

P49327
RSCFHIICLVGTISL

FGF7

16

P21781
LTLCAASIGHITLGS

SLC22A25

236

Q6T423
LVCREGESIQGSHVT

SEC14L5

591

O43304
LTGVGVLVSALKTCH

SLC15A5

256

A6NIM6
HCIVGSTIGFSLVAI

SLC20A2

116

Q08357
LDILIHNAGISSCGR

DHRS13

116

Q6UX07
SAVASLVCLLRHGGR

AGPAT2

41

O15120
TGVCALIAGATLHVA

PPM1F

256

P49593
HCSAGVGRTGTFVVI

PTPRA

441

P18433
TVHCSAGVGRTGVFI

PTPRF

1836

P10586
ARHVLVSCGLALGAQ

NYNRIN

1686

Q9P2P1
SVHCSAGVGRTGVFI

PTPRD

1841

P23468
VGVGLGCLLQISRSH

SLC8B1

501

Q6J4K2
AVSIGGILASRCLHV

ABCC1

1036

P33527
LARVGACILKHAVTG

PRXL2B

6

Q8TBF2
SHFRVVATGSGCALV

RPUSD3

221

Q6P087
LGASRFCLQLVGTVH

TAS2R41

51

P59536
GRCERILTGHTQSVT

NLE1

236

Q9NVX2
GAVLGISLEACSSVH

TRMT5

436

Q32P41
AVHSLLCEGGARVLT

TEDC2

411

Q7L2K0
IHGCIVAGATLALRT

SLC27A2

276

O14975
SALAHGCVALITRLV

SLC35G2

111

Q8TBE7
TRCGHGIVGTIVKAR

PDLIM4

256

P50479
TCRRCVVIGSGGILH

ST3GAL5

191

Q9UNP4
FHCTDLGVTILVNRG

SURF1

166

Q15526
TVTSGKVRHGALTCL

CDC42BPA

1316

Q5VT25
SLSGDHCIIGRTLVV

SOD1

106

P00441
GKILVHCAVGVSRSA

DUSP26

146

Q9BV47
HCAVGVSRSATLVLA

DUSP26

151

Q9BV47
CRVAIGIIVGHIQAS

NCKIPSD

331

Q9NZQ3
KGLATHILVGSVTCE

RIPOR2

271

Q9Y4F9
SVEVIRTLCLGGAHI

SHANK1

226

Q9Y566
RACHDTVTVLGLTVL

ADGRG5

451

Q8IZF4
EVVLRIHCRGAATGA

ADRA1D

301

P25100
REACITLGHLSSVLG

CLASP1

386

Q7Z460
KEGTVLRICSHVAGI

CNKSR1

166

Q969H4
CSRHGLAVGANTILL

CNNM4

291

Q6P4Q7
RPTAATGHTVTICVL

SLC7A14

556

Q8TBB6
GVGSEVSHRRTCVSL

XCL2

21

Q9UBD3
CRLVTFTHGVLSIGL

TLCD5

36

Q6ZRR5
ISNACGTIGLIHAIA

UCHL3

91

P15374
RLGILSVSSFHALVC

TIAM2

726

Q8IVF5
TRQCSLSVHAGIRGE

PJVK

166

Q0ZLH3
GASGCRILVTLLHTL

ACAT2

356

Q9BWD1
ELVGGLTCLTAQTHS

MRPL10

206

Q7Z7H8
GTSRHVSVGIFSLLC

SLC26A1

116

Q9H2B4
TSRHISVGIFGVLCL

SLC26A2

156

P50443
SLSRGTVCHRTGVQP

TECPR1

1101

Q7Z6L1
IRTLDCIHVLQTSGG

TRAF7

546

Q6Q0C0
VVVVGSSAFLLCHRR

TNFRSF8

396

P28908
SVRTKGRHICGGTLV

PRSS42P

96

Q7Z5A4
TAHTVGDGLTCRARV

STAB1

1571

Q9NY15
ESIQVTLECGLGHRT

VPS13C

2281

Q709C8
LETQAGLVGILHCSV

SIGLEC1

421

Q9BZZ2
LHRVGRGVSIGTTCL

VN1R4

86

Q7Z5H5
SRLCGSHQVILGLVC

TTC21A

306

Q8NDW8
LCHRGGVRAVAVDST

WDR46

356

O15213
AGGTRRLLSSHCTLV

PLEKHH1

751

Q9ULM0
VHCSAGIGRTGTIIV

PTPN6

451

P29350
LGLSTVTGLHCVGDT

TNFRSF4

21

P43489
GGSNHVTVSRVGRVC

SEMA3G

256

Q9NS98
RANGTHICAGTIIAS

PRSS50

131

Q9UI38
VLEGQSLRLVCVTHS

SIGLEC11

381

Q96RL6
VITTLKGHEGSVACL

WDFY1

191

Q8IWB7
RLSTLILHGGGTVCR

TERF2IP

41

Q9NYB0
GVILIVSHGSTLDSC

UBASH3A

581

P57075
VCHRLVKGLASVSEG

VWA5B1

496

Q5TIE3
GALTVGLVRQCQTIH

MOSMO

36

Q8NHV5
IISLTVTCGLLVASH

MOSMO

76

Q8NHV5
TARGICVSLGHSVAD

AMDHD2

201

Q9Y303