Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

ORC4 MACF1 NSF ATP6V0A4 MYO5C DNAH1

1.12e-04614266GO:0140657
GeneOntologyMolecularFunctionmechanosensitive monoatomic ion channel activity

PIEZO2 TMC3

2.46e-0418262GO:0008381
DomainGAR

MACF1 DST

3.24e-056282PS51460
Domain-

MACF1 DST

3.24e-0562823.30.920.20
Domain-

MACF1 DST

3.24e-0562823.90.1290.10
DomainGAS_dom

MACF1 DST

3.24e-056282IPR003108
DomainGAS2

MACF1 DST

3.24e-056282PF02187
DomainGAS2

MACF1 DST

3.24e-056282SM00243
DomainPlectin_repeat

MACF1 DST

4.53e-057282IPR001101
DomainPlectin

MACF1 DST

4.53e-057282PF00681
DomainPLEC

MACF1 DST

4.53e-057282SM00250
DomainActinin_actin-bd_CS

MACF1 DST

5.38e-0423282IPR001589
DomainACTININ_2

MACF1 DST

5.38e-0423282PS00020
DomainACTININ_1

MACF1 DST

5.38e-0423282PS00019
DomainSpectrin

MACF1 DST

5.38e-0423282PF00435
DomainSpectrin_repeat

MACF1 DST

8.58e-0429282IPR002017
DomainSpectrin/alpha-actinin

MACF1 DST

1.05e-0332282IPR018159
DomainSPEC

MACF1 DST

1.05e-0332282SM00150
DomainP-loop_NTPase

ADCY10 ORC4 NSF MYO5C YLPM1 DNAH1

1.37e-03848286IPR027417
DomainAAA

ORC4 NSF

2.74e-0352282PF00004
DomainATPase_AAA_core

ORC4 NSF

2.96e-0354282IPR003959
DomainSH3

DOCK1 MACF1 DST

4.04e-03216283PS50002
DomainSH3_domain

DOCK1 MACF1 DST

4.25e-03220283IPR001452
DomainCH

MACF1 DST

4.25e-0365282SM00033
Domain-

ADCY10 ORC4 NSF YLPM1 DNAH1

4.59e-037462853.40.50.300
DomainCH

MACF1 DST

4.91e-0370282PF00307
Domain-

MACF1 DST

5.05e-03712821.10.418.10
DomainCH

MACF1 DST

5.33e-0373282PS50021
DomainCH-domain

MACF1 DST

5.62e-0375282IPR001715
DomainEF-hand_7

MACF1 DST

7.17e-0385282PF13499
Pubmed

Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.

MACF1 DST

7.19e-07230211002341
Pubmed

Expression of the mouse Macf2 gene during inner ear development.

MACF1 DST

2.16e-06330212399109
Pubmed

Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13.

EEA1 NSF

4.31e-06430210458612
Pubmed

Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.

MACF1 DST

4.31e-0643028954775
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MKI67 MACF1 MPHOSPH10 DST TASOR2 YLPM1

1.73e-0565330622586326
Pubmed

Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion.

EEA1 NSF

2.01e-05830210903204
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

MKI67 MACF1 EEA1 DST NSF MYO5C YLPM1

2.11e-05102430724711643
Pubmed

Retrolinkin, a membrane protein, plays an important role in retrograde axonal transport.

EEA1 DST

2.58e-05930217287360
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MKI67 MACF1 MPHOSPH10 GTF2H3 CPED1 YLPM1

3.09e-0572430636232890
Pubmed

The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway.

MACF1 DST

3.94e-051130216815997
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

MACF1 EEA1 DST SERPINA12

4.77e-0523430436243803
Pubmed

Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain.

MKI67 DST

5.58e-05133029670011
Pubmed

Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins.

MKI67 MPHOSPH10

8.57e-051630229764992
Pubmed

The fibroblast growth factor receptor substrate 3 adapter is a developmentally regulated microtubule-associated protein expressed in migrating and differentiated neurons.

MKI67 EEA1

8.57e-051630219943849
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

DOCK1 ORC4 MACF1 NSF YLPM1

1.30e-0458230520467437
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

MACF1 DST

1.35e-042030221689717
Pubmed

Diverse Fgfr1 signaling pathways and endocytic trafficking regulate mesoderm development.

MKI67 EEA1

2.13e-042530238834239
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

MKI67 MACF1 DST NSF YLPM1

2.33e-0466030532780723
Pubmed

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.

MKI67 MPHOSPH10 YLPM1

2.82e-0414830332538781
Pubmed

Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation.

DOCK1 DST

3.08e-043030224472646
Pubmed

Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice.

MKI67 EEA1

3.29e-043130217765678
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

MKI67 MPHOSPH10 DST YLPM1

4.09e-0441030426949251
Pubmed

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

MKI67 DOCK1 BTBD16 CC2D2B

4.28e-0441530416385451
Pubmed

Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.

MKI67 MACF1 DST

4.76e-0417730322560297
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

MKI67 MPHOSPH10 GTF2H3 YLPM1

5.34e-0444030434244565
Pubmed

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.

MKI67 DST YLPM1

5.93e-0419130331177093
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

MACF1 GTF2H3 DST BHMT

7.45e-0448130428190767
Pubmed

Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk.

MKI67 MACF1

7.59e-044730232253237
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

MACF1 ATP6V0A4 TASOR2 DNAH1

8.35e-0449630431343991
CytobandEnsembl 112 genes in cytogenetic band chr10q26

MKI67 DOCK1 BTBD16

3.35e-04207303chr10q26
Cytoband7q34

TRBV23-1 ATP6V0A4

5.35e-031673027q34
CytobandEnsembl 112 genes in cytogenetic band chr7q34

TRBV23-1 ATP6V0A4

6.52e-03185302chr7q34
GeneFamilyEF-hand domain containing|Plakins

MACF1 DST

3.94e-058222939
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

MKI67 MPHOSPH10 YLPM1

1.32e-03181223694
GeneFamilyAAA ATPases

ORC4 NSF

1.88e-0353222413
GeneFamilyEF-hand domain containing

MACF1 DST

2.88e-02219222863
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 ADCY10 MIS18BP1 CPED1

6.40e-06181304c26d3cbbc592299786d79d1b15fc6bead2aafb9a
ToppCell18-Airway-Mesenchymal-Mesenchyme_RSPO2+|Airway / Age, Tissue, Lineage and Cell class

MKI67 MACF1 PIEZO2 DST

9.30e-061993047ac35e8f45dcdc702422dabd8f3e4d03e2bf61af
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DST DNAH1 CC2D2B

8.43e-05127303353484362448f27e8377447d0c26391b1da7acc5
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MACF1 MIS18BP1 DST

1.01e-04135303b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCelldroplet-Liver-LIVER_NPC-30m-Epithelial-Hepatocyte_(Midlobular)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINA12 BHMT DNAH1

1.10e-04139303e363c69b58cff8571ca75b91a3d052f9cbccac27
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DOCK1 DST CPED1

1.46e-0415330391e9d70a5d3f6fd68c284ed0cc113f03d7d1e10b
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DOCK1 DST CPED1

1.46e-04153303f17f62646633cf95c810dcd5328978058741b276
ToppCellfacs-Heart-Unknown-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIS18BP1 MYO5C BHMT

1.58e-041573032ac4695d9e4ca8d4ba19c555e9a1d86ac8f398ab
ToppCellfacs-Heart-Unknown-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIS18BP1 MYO5C BHMT

1.58e-041573038a393eece90fb9a1b7c356736bdb36277261fbd3
ToppCellfacs-Heart-Unknown-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIS18BP1 MYO5C BHMT

1.58e-041573038d30d8e6fae93afcada6bd68799439335cd65b69
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MACF1 PIEZO2 DST

1.67e-041603030293b244c063a62819690bf22bbc2681f8d15252
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MACF1 PIEZO2 DST

1.67e-041603033eaae86fa08f7651021316f8e5811bf48055591e
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MKI67 MIS18BP1 CPED1

2.07e-0417230329c8510f26527d487d0fc3543102d067cdb281a6
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 PIEZO2 MIS18BP1

2.10e-04173303f38bf7584e08d15a6e2c116b7c3551ba475a5e14
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_12|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MKI67 DST CPED1

2.10e-041733039c7386bf0a899882c733f0b4921a96afde032a7d
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_12|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MKI67 DST CPED1

2.10e-04173303a55f310c533432e9e26e400026a5b47245152976
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Myeloid-new-cluster|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 MIS18BP1 BHMT

2.14e-04174303718e14d9a4264456459bec4c062c94c3a848d43a
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 MIS18BP1 BHMT

2.17e-0417530361fdafba120fbda063d4dc05263d6f8d1dcab1e1
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 MIS18BP1 BHMT

2.17e-041753038de8031fdf2af187642833feb80caa64932897cf
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MACF1 PIEZO2 DST

2.29e-04178303ad3de3e03a401dac64431a541899445262246347
ToppCellfacs-Kidney-nan-3m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK1 PIEZO2 DST

2.44e-041823034c5d14e33ebdf117b5aa9e2f57aaa89aa51f72bf
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MKI67 MIS18BP1 CC2D2B

2.48e-0418330352af3c943116073c8ddd207b664342960b88929b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DST ATP6V0A4 MYO5C

2.64e-04187303f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

MACF1 PIEZO2 DST

2.64e-0418730392d468dde81125d51daf7abd4703741abe1ab91c
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 MIS18BP1 BHMT

2.68e-0418830361ae7405ab56570409bf35382dc0a038e4137c15
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

MACF1 PIEZO2 DST

2.77e-0419030371e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

MACF1 PIEZO2 DST

2.77e-0419030362a3ec1ae0829602b0569cc051210551644f1d46
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic-lymphocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

MKI67 ADCY10 IL26

2.81e-0419130356b45259dfc38bd5ea43b0e3adf47e7e2c043a5d
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MACF1 PIEZO2 DST

2.81e-041913036688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MACF1 PIEZO2 DST

2.85e-0419230399ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MACF1 PIEZO2 NSF

2.85e-041923031ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

MACF1 PIEZO2 DST

2.85e-0419230362904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MACF1 PIEZO2 DST

2.90e-041933039f69edc97b868d23998abc98928a2e89a885ef8a
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

MACF1 PIEZO2 DST

2.90e-041933035896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCellSevere_COVID-19-Myeloid-proliferating_Myeloid_cells|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

MKI67 DST CPED1

2.90e-041933030d85025690c9cd545cba30abc38acbdd6a39b153
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MACF1 PIEZO2 DST

2.90e-0419330399525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MACF1 PIEZO2 DST

2.90e-04193303b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK1 MACF1 DST

2.94e-041943030b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MKI67 DST CPED1

2.94e-04194303cb39850e9577015b6b9834e98c36b412bae7d462
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 DST CPED1

2.94e-0419430390efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MKI67 DST CPED1

2.94e-04194303408597c9aa302a44b112c1d612c21fbb0227a82a
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MKI67 DST CPED1

2.94e-04194303193cc20fefbd795a4ad59e401a95af47d30603e7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 DST CPED1

2.94e-04194303df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCellBAL-Severe-Myeloid-Myeloid|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MKI67 DST CPED1

2.94e-041943032360b5f995b360419de41612368cab9fb61781a1
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MACF1 PIEZO2 DST

2.94e-04194303b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MKI67 DST CPED1

2.94e-04194303903ae11708b0cb24538c6982abd57fe6fa95b8d3
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MACF1 PIEZO2 DST

2.94e-0419430371d3c7448b1734de54187f902f65649f9283bd4c
ToppCellBAL-Severe-Myeloid-Myeloid|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MKI67 DST CPED1

2.94e-0419430358406502a8cbcc3037f79a1b6a683df408297ae5
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MACF1 PIEZO2 DST

2.99e-041953034243190ad291d56694e2155954dbaa879c9d3844
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MACF1 PIEZO2 DST

2.99e-041953031cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MACF1 PIEZO2 DST

2.99e-041953030e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MACF1 PIEZO2 DST

2.99e-04195303df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK1 PIEZO2 CPED1

3.03e-041963036bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MACF1 PIEZO2 DST

3.03e-041963036730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MACF1 PIEZO2 DST

3.03e-0419630342e9828222a9663525d571633e8a454c30bfa7f8
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK1 PIEZO2 CPED1

3.03e-04196303c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MACF1 PIEZO2 DST

3.03e-041963031450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MACF1 PIEZO2 DST

3.03e-0419630321dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MACF1 PIEZO2 DST

3.03e-04196303cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MACF1 PIEZO2 DST

3.03e-041963039737a5f006d37b549f281e1863aca558e1e4dc99
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MACF1 PIEZO2 DST

3.03e-041963037d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell368C-Fibroblasts-Fibroblast-G-|368C / Donor, Lineage, Cell class and subclass (all cells)

MACF1 PIEZO2 DST

3.08e-04197303d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCell368C-Fibroblasts-Fibroblast-G|368C / Donor, Lineage, Cell class and subclass (all cells)

MACF1 PIEZO2 DST

3.08e-04197303156155c2f0c1a2461e45803da578af18ee221660
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MACF1 PIEZO2 DST

3.08e-0419730394a9603cbd3516fbcce871909693b88f20d41713
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MACF1 PIEZO2 DST

3.08e-0419730331a1852911bda38543916585fda34255fd62a134
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MKI67 MIS18BP1 DST

3.08e-04197303cd7e34318b4ae72b7b312fda8cc0e041c2ac4ab5
ToppCelltumor_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

MACF1 PIEZO2 DST

3.08e-0419730344f37a98f07c3e46a7e8fd3b64c2b2b44d5bbe40
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DOCK1 PIEZO2 DST

3.08e-0419730382b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MACF1 PIEZO2 DST

3.08e-041973030034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MACF1 PIEZO2 DST

3.08e-0419730313896ec65ccda0b928c91d41112dc01b480036b7
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|normal_Lung / Location, Cell class and cell subclass

MACF1 PIEZO2 DST

3.08e-041973036c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MACF1 PIEZO2 DST

3.08e-0419730311a4c417f035e554431a8f03be13b5eefa3530c0
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MACF1 PIEZO2 DST

3.12e-041983038f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell18-Distal|18 / Age, Tissue, Lineage and Cell class

MACF1 PIEZO2 DST

3.12e-04198303d635398c6529c514e77c0dc9299e9cf00330c9e7
ToppCellBronchial-10x5prime-Immune_Lymphocytic-T-T_CD8-gdT|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TDRD15 TRBV23-1 IL26

3.12e-041983039dc91a1101eef649a301f0147ecd5c028a9c2b12
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MACF1 PIEZO2 DST

3.12e-0419830317dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

MACF1 PIEZO2 DST

3.12e-04198303e0e47cf65774191981840b22905b2094b95abe0f
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MACF1 PIEZO2 DST

3.12e-04198303f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MKI67 MIS18BP1 DST

3.12e-04198303a11ac83dbd69d1c068971266d7c7343d114a6294
ToppCell15-Distal-Mesenchymal-Mesenchyme_RSPO2+|Distal / Age, Tissue, Lineage and Cell class

MACF1 PIEZO2 DST

3.12e-04198303e87d1fe2befbd32b0c723ab43b9de95495ea3ee3
ToppCellproximal-mesenchymal-Alveolar_Fibroblast|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MACF1 PIEZO2 DST

3.17e-041993037f4840ae6a888380feca722543e5e52783f3e35d
ToppCelldistal-mesenchymal-Alveolar_Fibroblast-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MACF1 PIEZO2 DST

3.17e-04199303fb23ecce41e31e2cc01814e3c0add756f489561f
ToppCellproximal-3-mesenchymal-Alveolar_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MACF1 PIEZO2 DST

3.17e-04199303301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCell18-Distal-Mesenchymal|Distal / Age, Tissue, Lineage and Cell class

MACF1 PIEZO2 DST

3.17e-04199303d65150d2e24c40aa82712e7f034f6772102bd293
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MACF1 DST CPED1

3.17e-0419930330d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MACF1 PIEZO2 DST

3.17e-0419930366a79732caf2f04c09b4d9832377aa01ca477677
ToppCell18-Distal-Mesenchymal-Mesenchyme_RSPO2+|Distal / Age, Tissue, Lineage and Cell class

MACF1 PIEZO2 DST

3.17e-0419930395403988caef322314f4ed15415ad1a9a987adc1
ToppCellproximal-mesenchymal-Alveolar_Fibroblast-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MACF1 PIEZO2 DST

3.17e-041993039a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCell343B-Fibroblasts-Fibroblast-G|343B / Donor, Lineage, Cell class and subclass (all cells)

MACF1 PIEZO2 DST

3.17e-04199303f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

BTBD16 CPED1 BHMT

3.17e-041993038ff0fdcbe9661b013913731ec8b53d84836ca865
ToppCelldistal-mesenchymal-Alveolar_Fibroblast|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MACF1 PIEZO2 DST

3.17e-04199303655d07cf9a2fd9b945a2ed4f824cba0297de72a8
ToppCell343B-Fibroblasts-Fibroblast-G-|343B / Donor, Lineage, Cell class and subclass (all cells)

MACF1 PIEZO2 DST

3.17e-041993039c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCellwk_15-18-Mesenchymal-Fibroblast-Alveolar_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MACF1 PIEZO2 DST

3.17e-041993036bce8e65859a35cfea1c210f9c9765952d492ed2
ToppCell(5)_Fibroblast-G|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

MACF1 PIEZO2 DST

3.17e-04199303b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MKI67 MIS18BP1 DST

3.17e-041993039940f347973bf976ee23fb4b1cf1f349d96c21df
ToppCellcellseq-Mesenchymal-Fibroblastic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MACF1 PIEZO2 DST

3.22e-042003038978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCellmedial-mesenchymal-Alveolar_Fibroblast-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MACF1 PIEZO2 DST

3.22e-042003035c0716bf375c8158f7dc2c82bf5eaf37af594dd0
ToppCellmedial-mesenchymal-Alveolar_Fibroblast|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MACF1 PIEZO2 DST

3.22e-04200303c22cbfecee00183dd4be678f116ab9fd9ad0a4dd
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PIEZO2 DST CPED1

3.22e-04200303cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellwk_20-22-Mesenchymal-Fibroblast-Alveolar_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MACF1 PIEZO2 DST

3.22e-042003030ed49c2177b58269ff7653db6be7d68633a5d34a
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

MACF1 DST TASOR2

6.15e-0550173GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

TDRD15 MACF1 DNAH1

1.09e-03200303EFO_0004611, EFO_0020945
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

TDRD15 MACF1 DNAH1

1.51e-03224303EFO_0004530, EFO_0008317
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

TDRD15 MACF1 DNAH1

1.90e-03243303EFO_0004612, EFO_0020944
Diseasecoffee consumption measurement, neuroticism measurement

NSF YLPM1

2.12e-0367302EFO_0006781, EFO_0007660
Diseasefeeling "fed-up" measurement

NSF YLPM1

2.72e-0376302EFO_0009588
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

TDRD15 MACF1 DNAH1

2.73e-03276303EFO_0004612, EFO_0020943
Diseasemigraine disorder, Headache

BTBD16 NSF

3.46e-0386302HP_0002315, MONDO_0005277
Diseasecortical thickness

MACF1 CPED1 NSF LRRC49 YLPM1

4.92e-031113305EFO_0004840
Diseaselipoprotein measurement

DOCK1 TDRD15

5.11e-03105302EFO_0004732
DiseaseDrug Use Disorders

DOCK1 MYO5C

6.10e-03115302C0013222
DiseaseDrug Dependence

DOCK1 MYO5C

6.10e-03115302C1510472
DiseaseDrug habituation

DOCK1 MYO5C

6.10e-03115302C0013170
DiseaseSubstance Dependence

DOCK1 MYO5C

6.10e-03115302C0038580
DiseaseSubstance Use Disorders

DOCK1 MYO5C

6.10e-03115302C0038586
DiseaseSubstance-Related Disorders

DOCK1 MYO5C

6.10e-03115302C0236969
DiseaseDrug abuse

DOCK1 MYO5C

6.10e-03115302C0013146
DiseaseOrganic Mental Disorders, Substance-Induced

DOCK1 MYO5C

6.10e-03115302C0029231

Protein segments in the cluster

PeptideGeneStartEntry
FLQQLEVFMKKNVDF

BHMT

141

Q93088
LNVFEQFQFMNKKTQ

CPED1

506

A4D0V7
QIQKFFFENFKNKDI

BTBD16

61

Q32M84
KIFQGQINKVFMFDK

ADCY10

326

Q96PN6
PLQFDFKVMFQQIFN

CC2D2B

521

Q6DHV5
FQMVYNEFQKFVQRK

ORC4

346

O43929
NQFLKMTTFNNKNIF

MIS18BP1

61

Q6P0N0
TINQQLNMFKVFQKE

DST

5316

Q03001
LKFKETNLVMLQQFN

LRRC49

471

Q8IUZ0
FFSKLQDQVKMQIND

MPHOSPH10

646

O00566
KMAAEFIQQFNNQAF

NSF

116

P46459
VLNNFISNQKMDFKE

MKI67

736

P46013
QKQQVQFMLKEFEAR

MACF1

4616

Q9UPN3
EKFRKIQIMDQNNFQ

DNAH1

936

Q9P2D7
NFNIKQMKDLFEQKA

EEA1

151

Q15075
MLNKKFLDQANFELQ

DOCK1

1006

Q14185
TKKQFMKNCQFQEQL

IL26

71

Q9NPH9
FQMKIQNFLNEFKNI

CXorf38

181

Q8TB03
FQNIQFQKDLMANIR

TMC3

51

Q7Z5M5
NEFQEIMKNINKFYD

TDRD15

506

B5MCY1
NKQQFRNMKQKFLVT

NBPF7P

51

P0C2Y1
VLKTFQNQEKFFMNR

MROH2B

671

Q7Z745
NFQNLEMAQKQINDF

SERPINA12

166

Q8IW75
LKVMDQQSFNKFIQA

PIEZO2

2461

Q9H5I5
QNQNKEFMLLISFQN

TRBV23-1

56

A0A0A0MS06
LQEKVNSFQNMKNQY

YLPM1

496

P49750
QFKDLNMNVNSFQRK

ATP6V0A4

36

Q9HBG4
AEFNKVMKNSNQFIF

TASOR2

2116

Q5VWN6
VMKNSNQFIFQDKEL

TASOR2

2121

Q5VWN6
NFMNVIFAAQKQNIL

GTF2H3

176

Q13889
NEKLQQQFNMHVFKL

MYO5C

456

Q9NQX4