Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	regulation of protein kinase C signaling	GPD1L FLT4 ADGRV1	2.45e-05	20	59	3	GO:0090036
Domain	Ig_I-set	FLT4 HMCN1 OBSCN MYOM2 HEPACAM2 MERTK CEACAM20 CDON	1.41e-07	190	59	8	IPR013098
Domain	I-set	FLT4 HMCN1 OBSCN MYOM2 HEPACAM2 MERTK CEACAM20 CDON	1.41e-07	190	59	8	PF07679
Domain	IGc2	FLT4 HMCN1 OBSCN MYOM2 HEPACAM2 CEACAM20 CDON	8.93e-06	235	59	7	SM00408
Domain	Ig_sub2	FLT4 HMCN1 OBSCN MYOM2 HEPACAM2 CEACAM20 CDON	8.93e-06	235	59	7	IPR003598
Domain	ig	FLT4 HMCN1 OBSCN MERTK CEACAM20 CDON	2.95e-05	190	59	6	PF00047
Domain	Immunoglobulin	FLT4 HMCN1 OBSCN MERTK CEACAM20 CDON	2.95e-05	190	59	6	IPR013151
Domain	IG	FLT4 HMCN1 OBSCN MYOM2 HEPACAM2 MERTK CEACAM20 CDON	5.06e-05	421	59	8	SM00409
Domain	Ig_sub	FLT4 HMCN1 OBSCN MYOM2 HEPACAM2 MERTK CEACAM20 CDON	5.06e-05	421	59	8	IPR003599
Domain	IG_LIKE	FLT4 HMCN1 OBSCN MYOM2 HEPACAM2 MERTK CEACAM20 CDON	1.47e-04	491	59	8	PS50835
Domain	fn3	TRIM9 OBSCN MYOM2 MERTK CDON	1.58e-04	162	59	5	PF00041
Domain	Ig-like_dom	FLT4 HMCN1 OBSCN MYOM2 HEPACAM2 MERTK CEACAM20 CDON	1.74e-04	503	59	8	IPR007110
Domain	-	FLT4 HMCN1 TRIM9 OBSCN MYOM2 HEPACAM2 MERTK CEACAM20 CDON	2.18e-04	663	59	9	2.60.40.10
Domain	FN3	TRIM9 OBSCN MYOM2 MERTK CDON	2.93e-04	185	59	5	SM00060
Domain	Ig-like_fold	FLT4 HMCN1 TRIM9 OBSCN MYOM2 HEPACAM2 MERTK CEACAM20 CDON	3.46e-04	706	59	9	IPR013783
Domain	FN3	TRIM9 OBSCN MYOM2 MERTK CDON	4.10e-04	199	59	5	PS50853
Domain	FN3_dom	TRIM9 OBSCN MYOM2 MERTK CDON	5.13e-04	209	59	5	IPR003961
Domain	-	HYOU1 PCIF1	7.48e-04	13	59	2	1.20.1270.10
Domain	HSP70_C	HYOU1 PCIF1	7.48e-04	13	59	2	IPR029048
Domain	TSP_1	HMCN1 ADAMTS9 C6	1.04e-03	63	59	3	PF00090
Domain	TSP1	HMCN1 ADAMTS9 C6	1.14e-03	65	59	3	SM00209
Domain	TSP1_rpt	HMCN1 ADAMTS9 C6	1.14e-03	65	59	3	IPR000884
Domain	TSP1	HMCN1 ADAMTS9 C6	1.14e-03	65	59	3	PS50092
Domain	Protein_kinase_ATP_BS	FLT4 STK17A BUB1 OBSCN MERTK MAP3K4	1.22e-03	379	59	6	IPR017441
Domain	VWFA	CACNA2D4 HMCN1 ITGAL	2.22e-03	82	59	3	PS50234
Domain	Pentatricopeptide_repeat	LRPPRC NCAPG2	2.38e-03	23	59	2	IPR002885
Domain	VWA	CACNA2D4 HMCN1 ITGAL	2.38e-03	84	59	3	SM00327
Domain	PROTEIN_KINASE_ATP	FLT4 STK17A BUB1 OBSCN MERTK MAP3K4	3.20e-03	459	59	6	PS00107
Domain	PROTEIN_KINASE_TYR	FLT4 OBSCN MERTK	3.58e-03	97	59	3	PS00109
Domain	Tyr_kinase_AS	FLT4 OBSCN MERTK	3.58e-03	97	59	3	IPR008266
Domain	VWF_A	CACNA2D4 HMCN1 ITGAL	3.79e-03	99	59	3	IPR002035
Domain	Prot_kinase_dom	FLT4 STK17A BUB1 OBSCN MERTK MAP3K4	4.35e-03	489	59	6	IPR000719
Domain	PROTEIN_KINASE_DOM	FLT4 STK17A BUB1 OBSCN MERTK MAP3K4	4.53e-03	493	59	6	PS50011
Pubmed	LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.	KRT7 LRPPRC HYOU1 HMCN1 MCM7 DYNC1H1	1.74e-07	142	60	6	30809309
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	RHOA ADAMTS9 TRIM9 TLN1 CEP290 PCIF1 OBSCN UNC93A C6 DYNC1H1	4.92e-07	736	60	10	29676528
Pubmed	Protein profile of tax-associated complexes.	RHOA RAG2 TAX1BP1	2.69e-06	16	60	3	14530271
Pubmed	SRPX and HMCN1 regulate cancer‑associated fibroblasts to promote the invasiveness of ovarian carcinoma.	HMCN1 SRPX	2.93e-06	2	60	2	31638245
Pubmed	The mammalian actin-binding protein 1 is critical for spreading and intraluminal crawling of neutrophils under flow conditions.	DBNL ITGAL	2.93e-06	2	60	2	22450813
Pubmed	A dual role for talin in NK cell cytotoxicity: activation of LFA-1-mediated cell adhesion and polarization of NK cells.	TLN1 ITGAL	2.93e-06	2	60	2	19124737
Pubmed	Loss of the obscurin-RhoGEF downregulates RhoA signaling and increases microtentacle formation and attachment of breast epithelial cells.	RHOA OBSCN	2.93e-06	2	60	2	25261370
Pubmed	Ikaros is required to survive positive selection and to maintain clonal diversity during T-cell development in the thymus.	RAG2 IKZF1	2.93e-06	2	60	2	23908463
Pubmed	Association study of FLT4 and HYDIN single nucleotide polymorphisms with atrial septal defect susceptibility in the Han Chinese population of Southwest China.	FLT4 HYDIN	2.93e-06	2	60	2	38581027
Pubmed	A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes.	TLN1 ITGAL	2.93e-06	2	60	2	15983060
Pubmed	Giant obscurin regulates migration and metastasis via RhoA-dependent cytoskeletal remodeling in pancreatic cancer.	RHOA OBSCN	2.93e-06	2	60	2	34826548
Pubmed	The RhoA transcriptional program in pre-T cells.	RHOA RAG2	2.93e-06	2	60	2	17716670
Pubmed	A novel nonsense mutation in CEP290 induces exon skipping and leads to a relatively mild retinal phenotype.	CEP290 MERTK	2.93e-06	2	60	2	20130272
Pubmed	Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.	SLC30A5 DAZAP1 SEC23IP DEPDC5 FABP4 MAP3K4	8.27e-06	276	60	6	28319085
Pubmed	Murine CCR9, a chemokine receptor for thymus-expressed chemokine that is up-regulated following pre-TCR signaling.	RAG2 CCR9	8.77e-06	3	60	2	10623805
Pubmed	Triggering the TCR Developmental Checkpoint Activates a Therapeutically Targetable Tumor Suppressive Pathway in T-cell Leukemia.	RAG2 IKZF1	8.77e-06	3	60	2	27354269
Pubmed	Developmental control of integrin expression regulates Th2 effector homing.	RAG2 ITGAL	8.77e-06	3	60	2	18354189
Pubmed	Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function.	RAG2 IKZF1	8.77e-06	3	60	2	19620627
Pubmed	Ikaros and RAG-2-mediated antisense transcription are responsible for lymphocyte-specific inactivation of NWC promoter.	RAG2 IKZF1	8.77e-06	3	60	2	25198102
Pubmed	Distinct Roles of LFA-1 and ICAM-1 on ILC2s Control Lung Infiltration, Effector Functions, and Development of Airway Hyperreactivity.	RAG2 ITGAL	8.77e-06	3	60	2	33193309
Pubmed	Pivotal role of plasmacytoid dendritic cells in inflammation and NK-cell responses after TLR9 triggering in mice.	RAG2 IKZF1	8.77e-06	3	60	2	22611152
Pubmed	Magnesium sensing via LFA-1 regulates CD8+ T cell effector function.	RAG2 ITGAL	8.77e-06	3	60	2	35051368
Pubmed	Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene.	RAG2 IKZF1	8.77e-06	3	60	2	15580273
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	KRT7 LRPPRC HYOU1 DAZAP1 TAX1BP1 DBNL MCM7 DYNC1H1	1.50e-05	647	60	8	26618866
Pubmed	Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma.	RHOA RAG2	1.75e-05	4	60	2	35443168
Pubmed	Cathepsin X cleavage of the beta2 integrin regulates talin-binding and LFA-1 affinity in T cells.	TLN1 ITGAL	1.75e-05	4	60	2	21454358
Pubmed	The Integrin LFA-1 Controls T Follicular Helper Cell Generation and Maintenance.	TLN1 ITGAL	1.75e-05	4	60	2	27760339
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	LRPPRC ADAMTS9 SYNE1 TLN1 TAX1BP1 OBSCN MYOM2	2.34e-05	497	60	7	23414517
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	RHOA LRPPRC HYOU1 DAZAP1 SYNE1 TLN1 SEC23IP DBNL SMARCA1 MCM7 DYNC1H1	2.84e-05	1425	60	11	30948266
Pubmed	Spatial, a gene expressed in thymic stromal cells, depends on three-dimensional thymus organization for its expression.	RAG2 IKZF1	2.92e-05	5	60	2	11196687
Pubmed	Ikaros prevents autoimmunity by controlling anergy and Toll-like receptor signaling in B cells.	RAG2 IKZF1	2.92e-05	5	60	2	31591571
Pubmed	The cytosolic protein talin induces an intermediate affinity integrin alphaLbeta2.	TLN1 ITGAL	2.92e-05	5	60	2	17591777
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	SIPA1L1 TLN1 DBNL IKZF1 NCAPG2 DYNC1H1	4.29e-05	370	60	6	22922362
Pubmed	Protein Kinase D1 regulates focal adhesion dynamics and cell adhesion through Phosphatidylinositol-4-phosphate 5-kinase type-l γ.	RHOA TLN1	4.37e-05	6	60	2	27775029
Pubmed	Cutting edge: thymocyte-independent and thymocyte-dependent phases of epithelial patterning in the fetal thymus.	RAG2 IKZF1	4.37e-05	6	60	2	12218095
Pubmed	Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model.	RAG2 IKZF1	4.37e-05	6	60	2	19111880
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	TRIM9 SYNE1 SIPA1L1 TLN1 ADGRV1	4.43e-05	225	60	5	12168954
Pubmed	Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.	LRPPRC HYOU1 SIPA1L1 TLN1 WDR70 MCM7	6.89e-05	403	60	6	35253629
Pubmed	Stage-specific control of early B cell development by the transcription factor Ikaros.	RAG2 IKZF1	8.14e-05	8	60	2	24509509
Pubmed	G alpha o mediates WNT-JNK signaling through dishevelled 1 and 3, RhoA family members, and MEKK 1 and 4 in mammalian cells.	RHOA MAP3K4	8.14e-05	8	60	2	18187455
Pubmed	Distinct bidirectional regulation of LFA1 and α4β7 by Rap1 and integrin adaptors in T cells under shear flow.	TLN1 ITGAL	1.05e-04	9	60	2	37267105
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	RHOA HYOU1 DAZAP1 TLN1 MCM7 IKZF1 MNDA NCAPG2 DYNC1H1	1.09e-04	1103	60	9	34189442
Pubmed	Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.	RHOA LRPPRC TLN1 DYNC1H1	1.15e-04	144	60	4	35681168
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	DAZAP1 CEP290 SMARCA1 MCM7 TAF7 HYDIN	1.58e-04	469	60	6	27634302
Pubmed	Neutrophil-activating therapy for the treatment of cancer.	RAG2 C6	1.59e-04	11	60	2	36706760
Pubmed	An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma.	BUB1 MCM7	1.59e-04	11	60	2	31693903
Pubmed	Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells.	RAG2 IKZF1	1.59e-04	11	60	2	23603794
Pubmed	Defining the membrane proteome of NK cells.	LRPPRC HYOU1 CEP290 BUB1 MCM7 ITGAL ARHGAP45 NCAPG2 DYNC1H1	1.67e-04	1168	60	9	19946888
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	HMCN1 OBSCN HEPACAM2 CDON	1.81e-04	162	60	4	25826454
Pubmed	Impact of lactobacilli on orally acquired listeriosis.	HMCN1 ADAMTS9 MNDA FABP4	1.81e-04	162	60	4	23012479
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	HMCN1 ADAMTS9 CDON	1.89e-04	64	60	3	22261194
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	TRIM9 TLN1 DBNL WDR70 ATP8B2 DYNC1H1	2.37e-04	506	60	6	30890647
Pubmed	Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.	LRPPRC HYOU1 DAZAP1 SMARCA1 MCM7 NCAPG2 DYNC1H1	2.46e-04	725	60	7	27025967
Pubmed	Essential role of Rac1 and Rac3 GTPases in neuronal development.	RHOA SLC30A5	2.63e-04	14	60	2	19126596
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	HMCN1 ADAMTS9 C6	3.02e-04	75	60	3	20637190
Pubmed	Human chromosome 7: DNA sequence and biology.	STK17A TAX1BP1 DBNL MCM7 IKZF1 NCAPG2	3.22e-04	536	60	6	12690205
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DAZAP1 ADAMTS9 TRIM9 SYNE1 SIPA1L1 CEP290 SEC23IP MERTK DYNC1H1	3.38e-04	1285	60	9	35914814
Pubmed	Loss of alpha3beta1 integrin function results in an altered differentiation program in the mouse submandibular gland.	RHOA TLN1	3.46e-04	16	60	2	11307167
Pubmed	Epithelial expression of Gata4 and Sox2 regulates specification of the squamous-columnar junction via MAPK/ERK signaling in mice.	KRT7 SYNE1	3.46e-04	16	60	2	33495473
Pubmed	Tracing the origin of adult intestinal stem cells.	RAG2 MUC2	3.46e-04	16	60	2	31092921
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	LRPPRC HYOU1 DAZAP1 SYNE1 TLN1 CEP290 MCM7 DYNC1H1	3.62e-04	1024	60	8	24711643
Pubmed	Docking motif-guided mapping of the interactome of protein phosphatase-1.	PCIF1 MCM7 HYDIN	3.65e-04	80	60	3	19389623
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	TLN1 SEC23IP DBNL MCM7 TAF7 DYNC1H1	3.66e-04	549	60	6	38280479
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	SYNE1 TLN1 MCM7 MYOM2	3.80e-04	197	60	4	20811636
Pubmed	Interactome of the Autoimmune Risk Protein ANKRD55.	LRPPRC TLN1 MCM7 DYNC1H1	3.80e-04	197	60	4	31620119
Pubmed	PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors.	RAG2 IKZF1	3.91e-04	17	60	2	11869689
Pubmed	Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice.	IKZF1 C6	3.91e-04	17	60	2	9175833
Pubmed	A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.	RHOA LRPPRC HYOU1 DAZAP1 TLN1 TAX1BP1 DYNC1H1	4.00e-04	786	60	7	29128334
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	LRPPRC SIPA1L1 CEP290 BUB1 SEC23IP WDR70 MCM7 NCAPG2 DYNC1H1	4.13e-04	1321	60	9	27173435
Pubmed	YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration.	RAG2 MUC2	4.40e-04	18	60	2	29249464
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	LRPPRC SYNE1 TLN1 DBNL SMARCA1 MCM7 DYNC1H1	4.55e-04	803	60	7	36517590
Pubmed	Simultaneous mutation detection in 90 retinal disease genes in multiple patients using a custom-designed 300-kb retinal resequencing chip.	CEP290 ADGRV1 MERTK	4.67e-04	87	60	3	20801516
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	LRPPRC HYOU1 SYNE1 TLN1 MCM7 HYDIN DYNC1H1	4.68e-04	807	60	7	30575818
Pubmed	Prethymic T-cell development defined by the expression of paired immunoglobulin-like receptors.	RAG2 IKZF1	4.91e-04	19	60	2	16292344
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	LRPPRC POLR1E TLN1 DBNL WDR70 SMARCA1 MCM7 NCAPG2 DYNC1H1	4.92e-04	1353	60	9	29467282
Pubmed	PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis.	LRPPRC TLN1 MCM7	5.15e-04	90	60	3	30699358
Pubmed	BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.	SLC30A5 TLN1 SEC23IP DBNL	5.37e-04	216	60	4	31519766
Pubmed	Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.	TLN1 C6 DYNC1H1	5.50e-04	92	60	3	37343697
Pubmed	An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.	LRPPRC HYOU1 TLN1 MCM7 DYNC1H1	6.17e-04	397	60	5	21319273
Pubmed	SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.	RHOA LRPPRC HYOU1 DAZAP1 TLN1 MCM7	6.21e-04	607	60	6	39147351
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	RHOA SIPA1L1 TLN1 MCM7 DYNC1H1	6.31e-04	399	60	5	37536630
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SYNE1 SIPA1L1 TLN1 DYNC1H1 MAP3K4	6.90e-04	407	60	5	12693553
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	LRPPRC TRIM9 SIPA1L1 DYNC1H1	7.02e-04	232	60	4	25515538
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	GPD1L LRPPRC HYOU1 TRIM9 SYNE1 SIPA1L1 TLN1 DBNL DYNC1H1	7.34e-04	1431	60	9	37142655
Pubmed	Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.	KRT7 TLN1 DBNL DYNC1H1	7.36e-04	235	60	4	28378594
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	RHOA LRPPRC MCM7 DYNC1H1	7.60e-04	237	60	4	29564676
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	GPD1L LRPPRC HYOU1 TLN1 SEC23IP MCM7 DYNC1H1	7.70e-04	878	60	7	37223481
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KRT7 LRPPRC HYOU1 SYNE1 SEC23IP DBNL SMARCA1 MYOM2 MNDA	7.76e-04	1442	60	9	35575683
Pubmed	KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.	LRPPRC TLN1 DYNC1H1	7.85e-04	104	60	3	36055981
Pubmed	SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation.	SMARCA1 MCM7	7.88e-04	24	60	2	18425126
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	LRPPRC HYOU1 TLN1 SEC23IP MCM7 DYNC1H1	8.04e-04	638	60	6	33239621
Pubmed	Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.	TRIM9 TLN1 MCM7	8.53e-04	107	60	3	30995489
Pubmed	Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen.	KRT7 BUB1	8.56e-04	25	60	2	17388661
Pubmed	Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.	ADAMTS9 CDON	8.56e-04	25	60	2	29475039
Pubmed	Loss of connectin novex-3 leads to heart dysfunction associated with impaired cardiomyocyte proliferation and abnormal nuclear mechanics.	SYNE1 OBSCN	8.56e-04	25	60	2	38877142
Pubmed	Expanding the substantial interactome of NEMO using protein microarrays.	FLT4 MCM7 MERTK	9.00e-04	109	60	3	20098747
Pubmed	Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation.	RAG2 FLT4	9.26e-04	26	60	2	20978081
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	LRPPRC HYOU1 DAZAP1 SMARCA1 MCM7 DYNC1H1	9.96e-04	665	60	6	30457570
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	FLT4 HYOU1 C6 MERTK	1.03e-03	257	60	4	16335952
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	SEC23IP WDR70 SMARCA1 MCM7 NCAPG2	1.09e-03	451	60	5	36168627
Interaction	LINC01554 interactions	KRT7 LRPPRC HYOU1 HMCN1 MCM7 DYNC1H1	3.30e-06	142	58	6	int:LINC01554
Interaction	GRWD1 interactions	RHOA LRPPRC FLT4 POLR1E MCM7 MERTK MNDA DYNC1H1	1.51e-05	390	58	8	int:GRWD1
Cytoband	Ensembl 112 genes in cytogenetic band chr3p21	MUSTN1 RHOA CCR9 PRSS42P	7.93e-04	316	60	4	chr3p21
Cytoband	Xp21.1	MKRN4P SRPX	9.17e-04	34	60	2	Xp21.1
Cytoband	7p13	STK17A DBNL	1.21e-03	39	60	2	7p13
Cytoband	Ensembl 112 genes in cytogenetic band chr9p13	POLR1E TLN1 ANKRD18B	1.56e-03	174	60	3	chr9p13
Cytoband	Ensembl 112 genes in cytogenetic band chr7p13	STK17A DBNL	2.22e-03	53	60	2	chr7p13
Cytoband	3p21.3	RHOA CCR9	2.74e-03	59	60	2	3p21.3
Cytoband	Ensembl 112 genes in cytogenetic band chr2q13	BUB1 MERTK	2.74e-03	59	60	2	chr2q13
Cytoband	11q24.2	CDON OR8B3	3.12e-03	63	60	2	11q24.2
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	FLT4 HMCN1 OBSCN MYOM2 HEPACAM2 MERTK CEACAM20 CDON	9.26e-09	161	48	8	593
GeneFamily	Immunoglobulin like domain containing	FLT4 MYOM2 HEPACAM2 MERTK CEACAM20 CDON	1.16e-05	193	48	6	594
GeneFamily	Fibronectin type III domain containing	TRIM9 OBSCN MYOM2 MERTK CDON	6.42e-05	160	48	5	555
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PCIF1 MCM7 IKZF1 HYDIN	1.34e-03	181	48	4	694
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	FLT4 MERTK	5.05e-03	40	48	2	321
Coexpression	KLEIN_TARGETS_OF_BCR_ABL1_FUSION	RAG2 IKZF1 ITGAL MNDA	3.52e-06	46	59	4	M2569
Coexpression	GSE21670_UNTREATED_VS_IL6_TREATED_CD4_TCELL_DN	CACNA2D4 SYNE1 SIPA1L1 IKZF1 TAF7 ARHGAP45	5.89e-06	200	59	6	M7441
Coexpression	CAIRO_HEPATOBLASTOMA_CLASSES_UP	LRPPRC TCAF1 DAZAP1 BUB1 SEC23IP SMARCA1 UNC93A MCM7 NCAPG2	8.63e-06	612	59	9	M4772
Coexpression	FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP	HYOU1 CCR9 IKZF1 MYOM2	4.90e-05	89	59	4	M6434
Coexpression	VAN_DEN_BIGGELAAR_PBMC_PREVNAR_9MO_INFANT_STIMULATED_VS_UNSTIMULATED_9MO_DN	MERTK FABP4	4.96e-05	5	59	2	M40949
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HPROGM	GPD1L BUB1 ADGRV1 NCAPG2 HYDIN CDON	6.58e-05	307	59	6	M39058
Coexpression	GSE11961_PLASMA_CELL_DAY7_VS_MEMORY_BCELL_DAY40_DN	RAG2 HYOU1 TRIM9 MYOM2 CEACAM20	8.41e-05	198	59	5	M9396
Coexpression	GSE22886_NAIVE_VS_MEMORY_TCELL_DN	SLC30A5 DAZAP1 CCR9 MUC2 ATP8B2	8.61e-05	199	59	5	M4417
Coexpression	GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_MAC_UP	HYOU1 TAX1BP1 SMARCA1 MERTK MUC2	8.82e-05	200	59	5	M5241
Coexpression	GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDC_UP	BUB1 MCM7 HEPACAM2 ARHGAP45 CDON	8.82e-05	200	59	5	M3791
Coexpression	GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_UP	SYNE1 CCR9 SIPA1L1 ITGAL MAP3K4	8.82e-05	200	59	5	M7148
ToppCell	facs-Trachea-nan-3m-Lymphocytic\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAG2 CCR9 BUB1 IKZF1 ITGAL ARHGAP45	2.24e-07	191	60	6	89eb4e30052d0d4a2952157ca743291900ce8de2
ToppCell	facs-Trachea-nan-3m-Lymphocytic-T_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAG2 CCR9 BUB1 IKZF1 ITGAL ARHGAP45	2.24e-07	191	60	6	0bf575eba311745fb75f9523f7fc81f73848e25d
ToppCell	facs-Trachea-nan-3m-Lymphocytic-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAG2 CCR9 BUB1 IKZF1 ITGAL ARHGAP45	2.24e-07	191	60	6	c57df363e3a6e61d2bdca1955330f1899b964267
ToppCell	droplet-Liver-HEPATOCYTES-1m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUSTN1 TSPAN15 C6 ITGAL MNDA	2.27e-06	157	60	5	b527e88382c8d21188a0f222b3302523e8816dfc
ToppCell	Club-club-16\|World / Class top	RHOA KRT7 HMCN1 ADAMTS9 MNDA	2.90e-06	165	60	5	684f3c4872bd630d3f744f15d57dccfd34e96160
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUSTN1 KRT7 C6 ADGRV1 HYDIN	3.26e-06	169	60	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 TCAF1 FLT4 HMCN1 FABP4	3.97e-06	176	60	5	c4d9166e5bbb7ca544107db14e4374289f5de6bd
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 TCAF1 FLT4 HMCN1 FABP4	3.97e-06	176	60	5	d58ef51002ea50b3037636038214bbb7454cb503
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 HYOU1 CCR9 HEPACAM2 NCAPG2	4.08e-06	177	60	5	c6812679aa6522d03bd29144e71c5fae6a92325e
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 HYOU1 CCR9 HEPACAM2 NCAPG2	4.08e-06	177	60	5	ff97398d2adb83063b7c53a264bfae86ea7ea304
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 OBSCN MYOM2 ADGRV1 HYDIN	4.93e-06	184	60	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 OBSCN MYOM2 ADGRV1 HYDIN	4.93e-06	184	60	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 OBSCN MYOM2 ADGRV1 HYDIN	4.93e-06	184	60	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAG2 HMCN1 CCR9 ARHGAP45 CEACAM20	5.06e-06	185	60	5	aa2c36e2cce0f0a536cd1dfc3788b6fee6f21b6b
ToppCell	10x5'v1-week_12-13-Endothelial-stroma-sinusoidal_EC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TSPAN15 FLT4 HMCN1 ADAMTS9 FABP4	5.20e-06	186	60	5	e8ead5634686ebaa6a230eea69795d923ce9939d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BUB1 IKZF1 ITGAL ARHGAP45 NCAPG2	5.33e-06	187	60	5	73931a5ea73799095daff100b5f18853c57c74dc
ToppCell	facs-Trachea-3m-Hematologic-lymphocytic-T_cell-T_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCR9 BUB1 IKZF1 ITGAL ARHGAP45	5.62e-06	189	60	5	286fcf22a2766cf435cd22f0986b1ca007d5b75a
ToppCell	facs-Trachea-3m-Hematologic-lymphocytic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCR9 BUB1 IKZF1 ITGAL ARHGAP45	5.62e-06	189	60	5	815631878564b805f3dc30877c5804c3ddb8641b
ToppCell	facs-Trachea-3m-Hematologic-lymphocytic-T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCR9 BUB1 IKZF1 ITGAL ARHGAP45	5.62e-06	189	60	5	035e5af872fcb8b527fa85dbcaa56e3aaff24531
ToppCell	ASK452-Immune-NK_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	SYNE1 IKZF1 MYOM2 ADGRV1 ITGAL	6.06e-06	192	60	5	f04ee5aaa54c39b7493098fb3d2f78168d6b8060
ToppCell	RV-09._Endothelium_I\|World / Chamber and Cluster_Paper	FLT4 HMCN1 ADAMTS9 SYNE1 FABP4	6.22e-06	193	60	5	e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCell	RV-09._Endothelium_I\|RV / Chamber and Cluster_Paper	FLT4 HMCN1 ADAMTS9 SYNE1 FABP4	6.38e-06	194	60	5	7b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|367C / Donor, Lineage, Cell class and subclass (all cells)	BUB1 MCM7 MNDA NCAPG2 FABP4	6.38e-06	194	60	5	a12b64945e10f00aa983678a02586c59badc1570
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS9 BUB1 SRPX NCAPG2 FABP4	6.70e-06	196	60	5	eb8c9a4a5eb21d43ff7b25deae5896c236f669b9
ToppCell	LPS_only-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT\|LPS_only / Treatment groups by lineage, cell group, cell type	STK17A MCM7 IKZF1 ITGAL ARHGAP45	7.22e-06	199	60	5	b62a756b5472972156d05051a58671a58bef1f16
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	STK17A MCM7 IKZF1 ITGAL ARHGAP45	7.22e-06	199	60	5	c23a53a20487a8abfeb91fa5fc9c06823dd657e9
ToppCell	390C-Lymphocytic\|390C / Donor, Lineage, Cell class and subclass (all cells)	STK17A IKZF1 MYOM2 ITGAL ARHGAP45	7.22e-06	199	60	5	d66747762011459ef1d6d311d4a579f245a23be0
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BUB1 MCM7 MNDA NCAPG2 FABP4	7.39e-06	200	60	5	5e1b38e2aa8901bfb2623249f7b6302e97d56ace
ToppCell	Biopsy_IPF-Immune-Proliferating_Macrophages\|Biopsy_IPF / Sample group, Lineage and Cell type	BUB1 MCM7 MNDA NCAPG2 FABP4	7.39e-06	200	60	5	8abb2c25422717e994468ac02d8260344341467f
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CCR9 SRPX MNDA FABP4	1.96e-05	118	60	4	3cebd17f4688cd43fe1283dc60957e87d5536810
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CCR9 SRPX MNDA FABP4	1.96e-05	118	60	4	61b00b001edb1954a5fffaf4dfe71708124a45e5
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CCR9 SRPX MNDA FABP4	1.96e-05	118	60	4	71f63efc641cd07c870f7695118fb244929c1536
ToppCell	Mild/Remission-B_intermediate-1\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TCAF1 FLT4 HMCN1 ARHGAP45	2.30e-05	123	60	4	69b7f2f4604bf221a0ff581c51de743e8a4c0537
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC9A4 ADAMTS9 MYOM2 MUC2	2.61e-05	127	60	4	9bc55cb9f4bddb274930784d12a83b9dceb35cb7
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BUB1 UNC93A ADGRV1 HYDIN	4.39e-05	145	60	4	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	PND01-03-samps-Myeloid-Granulocyte\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	IKZF1 ITGAL ARHGAP45 MNDA	4.88e-05	149	60	4	7bdb396de8a1ef27ab0c2aaf1452576f4b0b5561
ToppCell	PND01-03-samps-Myeloid-Granulocyte-neutrophil__Lgals3-negative\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	IKZF1 ITGAL ARHGAP45 MNDA	4.88e-05	149	60	4	50f53018e525b3d252caa8bed9e075b1bb1086dd
ToppCell	droplet-Liver-HEPATOCYTES-1m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUSTN1 TSPAN15 C6 ITGAL	5.54e-05	154	60	4	66c93733116e31b65dfb4b0b00de5c39d19cdb84
ToppCell	droplet-Liver-Hepatocytes-18m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C6 MERTK ITGAL NCAPG2	5.83e-05	156	60	4	d72c2f5f72d269e29033f8728d924e0d4c8772c7
ToppCell	P28-Hematopoietic-Immune-immune_cell_unspecified\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SLC9A4 IKZF1 ITGAL ARHGAP45	5.98e-05	157	60	4	a70f93aff07b6b7a9efce33b12b024116648dc0a
ToppCell	P28-Hematopoietic-Immune\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SLC9A4 IKZF1 ITGAL ARHGAP45	5.98e-05	157	60	4	b1f520b1e0ea7abb19d0dd27021eafbea0fd90cd
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1-Excitatory_Neuron.Slc17a7.Parm1.Tshz2_(Deep_layer_pyramidal_cells--layer_5)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	UNC93A HEPACAM2 CEACAM20	6.27e-05	57	60	3	d80eb5ade3c90344b67811e7f313c7d0720715f0
ToppCell	facs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRIM9 IKZF1 ITGAL ARHGAP45	6.43e-05	160	60	4	e4516b093003275084fc327d1597394a436754eb
ToppCell	PCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	IKZF1 ITGAL ARHGAP45 MNDA	6.43e-05	160	60	4	7f1b58641ba149d20420fafad34ba78a65a2c701
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEPACAM2 ITGAL ARHGAP45 MNDA	6.43e-05	160	60	4	94e4f5fc2156dd8163811c3b8b0781ea9b3f2e06
ToppCell	facs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRIM9 IKZF1 ITGAL ARHGAP45	6.43e-05	160	60	4	0a507e3d59d7f744d0201a531ea84fa97a68aedb
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SRPX C6 FABP4 CDON	6.59e-05	161	60	4	4f25eeabb841b0b9204cdd4e71d5e131e7868184
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SRPX C6 FABP4 CDON	6.59e-05	161	60	4	a006491c991e6a134be20ad75092a91f3b7c3c91
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BUB1 UNC93A ADGRV1 HYDIN	6.75e-05	162	60	4	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	droplet-Pancreas-Endocrine-18m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF1 ITGAL ARHGAP45 MNDA	6.91e-05	163	60	4	644c8a8af6a378fced4c70dec9a0de906f8d6e69
ToppCell	droplet-Pancreas-Endocrine-18m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF1 ITGAL ARHGAP45 MNDA	6.91e-05	163	60	4	aaff80d254131d1f1230bb12b6f43bc061ab5ab3
ToppCell	droplet-Pancreas-Endocrine-18m-Hematologic\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF1 ITGAL ARHGAP45 MNDA	6.91e-05	163	60	4	8b0f8a2d5b38f3bbff265211a7607acc85fa38b0
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUSTN1 GPD1L ADGRV1 FABP4	7.08e-05	164	60	4	b77995958c938e10a526118f75d78cee72e0b207
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLR1E CCR9 MCM7 NCAPG2	7.08e-05	164	60	4	5621c2e3fae84d5a2e4f1595e454bcb3a2b3f93c
ToppCell	droplet-Fat-Scat-21m\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT7 DBNL MYOM2 FABP4	7.25e-05	165	60	4	3f0c2486ea357d10dad0b703cf75cc29bdd5b5cf
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1-Excitatory_Neuron.Slc17a7.Reln_(Medial_entorrhinal_cortexm,_Reln+/Cbln1+)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	OBSCN HEPACAM2 ITGAL	7.68e-05	61	60	3	5e855b5462f42b7a1d0bbd518cc11072342ce0cc
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1-Excitatory_Neuron.Slc17a7.Reln_(Medial_entorrhinal_cortexm,_Reln+/Cbln1+)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	OBSCN HEPACAM2 ITGAL	7.68e-05	61	60	3	2fc13475581431f82e0b5ef42e18cd29c9787666
ToppCell	PCW_05-06-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	IKZF1 ITGAL ARHGAP45 MNDA	7.77e-05	168	60	4	907692c1f03d3c9889ba1bed5a4844e2c379db8e
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUSTN1 ITGAL ATP8B2 FABP4	7.77e-05	168	60	4	e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCell	droplet-Liver-Npc\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF1 C6 ITGAL ARHGAP45	8.13e-05	170	60	4	09c836840216905d545a25a4fc1bbd0699576c77
ToppCell	droplet-Trachea-nan-3m-Myeloid-macrophage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF1 HEPACAM2 ITGAL ARHGAP45	8.51e-05	172	60	4	f6c00a6a7e81aaf96c55eb3a3c88e3719f102ea0
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IKZF1 HEPACAM2 ITGAL ARHGAP45	8.51e-05	172	60	4	f3bbe3f069ad070778430d1a6cd9db0a76deb8de
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BUB1 MCM7 HEPACAM2 NCAPG2	8.51e-05	172	60	4	eba1568d4307e91c94fc616549057cbed8df5840
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BUB1 IKZF1 ARHGAP45 MNDA	8.51e-05	172	60	4	ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IKZF1 ITGAL ARHGAP45 MNDA	8.51e-05	172	60	4	f6b4754a7e4b3e38030316a0ae00d932bfa87e41
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Hematologic-hematopoietic_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR9 UNC93A IKZF1 ARHGAP45	8.70e-05	173	60	4	7456a417c5c1d4ba25f9489065aae322421308a6
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Hematologic-hematopoietic_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR9 UNC93A IKZF1 ARHGAP45	8.70e-05	173	60	4	35586a9e5f15b41609b6224e33eb3aa3cb7e03b7
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Hematologic\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR9 UNC93A IKZF1 ARHGAP45	8.70e-05	173	60	4	cd635751f999e12b14c0accfa1c4c1fd3c1d4540
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STK17A IKZF1 MYOM2 ITGAL	8.90e-05	174	60	4	7ebf06076946729c1af25109df6066731097c3b1
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STK17A IKZF1 MYOM2 ITGAL	8.90e-05	174	60	4	90961e8839514985712b8b986aec3391bb249ba7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BUB1 IKZF1 ARHGAP45 NCAPG2	8.90e-05	174	60	4	7b318796728001c17b4043d2b033330c7be40c78
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STK17A IKZF1 MYOM2 ITGAL	8.90e-05	174	60	4	c4b0987d9394f977fe6bc6a4214a6d8d73d0abcc
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BUB1 MCM7 HEPACAM2 NCAPG2	8.90e-05	174	60	4	09b091e24317c3f7bac043f04762a533e30793de
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IKZF1 ITGAL ARHGAP45 MNDA	9.10e-05	175	60	4	e991ffa4d1d278a011592b9915cd35fe76db20cc
ToppCell	3'-GW_trimst-1-LargeIntestine-Hematopoietic-T_cells-NK_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STK17A IKZF1 ITGAL ARHGAP45	9.10e-05	175	60	4	d427c1eaea805046b1e4944d374adc7095f710a1
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 HEPACAM2 ADGRV1 HYDIN	9.10e-05	175	60	4	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCR9 IKZF1 ITGAL ARHGAP45	9.10e-05	175	60	4	24f07bc6583129835bc67c04dabf5e82f6b8c369
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 HEPACAM2 ADGRV1 HYDIN	9.30e-05	176	60	4	c6484334187f64cd00cd35e77d8ae436556b4260
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IKZF1 ITGAL ARHGAP45 MNDA	9.30e-05	176	60	4	926ed37e636fe4dd3a18731cea15761f0c2c285a
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 MYOM2 ITGAL ARHGAP45	9.51e-05	177	60	4	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	droplet-Lung\|droplet / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TLN1 IKZF1 ITGAL ARHGAP45	9.51e-05	177	60	4	e1555e45880c04fcc89e1234e97897d27246250f
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 MYOM2 ITGAL ARHGAP45	9.51e-05	177	60	4	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	SYNE1 MYOM2 ITGAL ARHGAP45	9.51e-05	177	60	4	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	SYNE1 MYOM2 ITGAL ARHGAP45	9.51e-05	177	60	4	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SYNE1 MYOM2 ITGAL ARHGAP45	9.51e-05	177	60	4	d5aeda113afaa2425874394610344570c9078478
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	STK17A IKZF1 ITGAL ARHGAP45	9.51e-05	177	60	4	f1efd9c3074d5635700fe7fbebf3dd0b1e0a84f1
ToppCell	droplet-Lung\|droplet / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TLN1 IKZF1 ITGAL ARHGAP45	9.51e-05	177	60	4	dd35d534ba09237a37ac58cca184e5d84d3b36ac
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEPACAM2 ITGAL ARHGAP45 MNDA	9.72e-05	178	60	4	ee674e379ee57e40eb2560ff5ed4c13d8db7ed9d
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEPACAM2 ITGAL ARHGAP45 MNDA	9.72e-05	178	60	4	6c45bf197d6c1be0ef7d3a644c0062acf1e24e4d
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-macrophage\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEPACAM2 ITGAL ARHGAP45 MNDA	9.72e-05	178	60	4	cd85dcefe94ee742db64b63e105e13532321894a
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA2D4 TLN1 MERTK MNDA	9.72e-05	178	60	4	aa9f68a66e292f331faef881bbd0d028f0f2b0c5
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Hematopoietic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IKZF1 ITGAL ARHGAP45 MNDA	9.93e-05	179	60	4	716856b2c7c660bf5ce00e63efeda6ed121f2baa
ToppCell	LPS-IL1RA-Lymphocytic_NKT\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	STK17A IKZF1 ITGAL ARHGAP45	9.93e-05	179	60	4	5ccf0824611ded5c673d94dff3048aedac12f1a8
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 DBNL HEPACAM2 FABP4	9.93e-05	179	60	4	bc93883c2094f2e5bfed79facd4994a23968d875
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 DBNL HEPACAM2 FABP4	9.93e-05	179	60	4	0cef6d2eab2015cac0dd340532b24bfec9707330
ToppCell	facs-Brain_Myeloid-Cortex-24m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 DBNL HEPACAM2 FABP4	9.93e-05	179	60	4	bb2410b3934fcc53396b96b48e0d9843df159b89
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 DBNL HEPACAM2 FABP4	9.93e-05	179	60	4	065241799cea30da62cb3b6f2f1970bd1b0f4e2b
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Endothelial\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUSTN1 FLT4 ADAMTS9 FABP4	1.01e-04	180	60	4	f9b7d5eb7b6ea72253c89bdc351ad2b4a53f7d8e
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-SELL+_CD4_T\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCR9 IKZF1 ITGAL ARHGAP45	1.01e-04	180	60	4	702673c0b7c5b0d22a6af3884374804b8c4d6254
ToppCell	Adult-Immune-natural_killer_cell-D175\|Adult / Lineage, Cell type, age group and donor	STK17A IKZF1 MYOM2 ITGAL	1.01e-04	180	60	4	fc59e28f39e7d4fb1bcc7205202cf39224b70d7b
Disease	glycerate measurement	HMCN1 CCR9	4.06e-04	15	59	2	EFO_0021029
Disease	Disorder of eye	CACNA2D4 CEP290 ADGRV1 MERTK	8.65e-04	212	59	4	C0015397
Disease	Leber Congenital Amaurosis	CEP290 MERTK	8.85e-04	22	59	2	C0339527
Disease	chronic widespread pain	WDR70 CDON	9.68e-04	23	59	2	EFO_0010099
Disease	retinal degeneration (implicated_via_orthology)	CEP290 MERTK	1.99e-03	33	59	2	DOID:8466 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
ASKVDVEQVVMYCKE	BUB1	226	O43683
EQKDMVTFYCTTKDV	CEACAM20	81	Q6UY09
DVTCMVQYATKDGKA	ADGRV1	1031	Q8WXG9
MAGKSTCKLVQFTEY	ADGRV1	5786	Q8WXG9
EEATGYKKCLEMTIN	ANKRD18B	711	A2A2Z9
SQYGEVVDCVIMKDK	DAZAP1	31	Q96EP5
KQETAVNIGYSCKML	ATP8B2	696	P98198
SKDKVCGICMEVVYE	MKRN4P	311	Q13434
NEVSDKIYVMSIVCK	RAG2	101	P55895
VKNEKVMCGYISEDT	DEPDC5	146	O75140
IKSKTYQVMRECEQA	MUSTN1	36	Q8IVN3
KNKAEEAMATYRTCV	ARHGAP45	456	Q92619
GSYICKMKINNEEIV	MERTK	171	Q12866
IAEVKAQYEEMAKCS	KRT7	261	P08729
EKFCETTIGSKVMEN	GPD1L	161	Q8N335
FMATCKYNNTVEIVK	MUC2	4431	Q02817
VTMNTPVEKLTDYCK	LRPPRC	381	P42704
VVSTSGEQMKVYKCE	IKZF1	451	Q13422
VSKKNIISYVGCMTQ	OR8B3	86	Q8NGG8
SCIFMYVKTSAKEGV	OR6C76	251	A6NM76
SEVKPKMVVATYTCD	MCM7	171	P33993
YVCVAVNVAGMTDKK	HMCN1	2361	Q96RW7
IRKSQKYDVVCEGTM	OBSCN	2866	Q5VST9
AVKCIIGTYMSVVDD	ADAMTS9	1131	Q9P2N4
GSTVCTIVTYQMVKT	HYOU1	236	Q9Y4L1
NVKAEGYTMNVEIKC	HYDIN	4181	Q4G0P3
NVVCIRYKGEMVKVS	PCIF1	426	Q9H4Z3
YCVKMGSSTSEKTLN	C6	896	P13671
VEQYTKEMEKNTCII	CEP290	371	O15078
ATEVKYNASVKCDRM	CACNA2D4	1071	Q7Z3S7
KISGVTVEDVGMYQC	CDON	366	Q4KMG0
YSQIKEESGIAICTM	CCR9	186	P51686
YATLMTQCKEGAQKE	DYNC1H1	3026	Q14204
VASEKVAQKTMDYVC	HEPACAM2	301	A8MVW5
VECVMKGVTSTRVYE	FABP4	116	P15090
ECIMEKVAKASGANY	DBNL	126	Q9UJU6
ITISDYSECKGVMEI	MNDA	266	P41218
YSECKGVMEIKEASS	MNDA	271	P41218
KVYTCISVDTGELMA	MAP3K4	1356	Q9Y6R4
SQTKTYREKMDSCIE	POLR1E	126	Q9GZS1
YKTADICQMLVSTVD	TAF7	86	Q15545
YMECSAKTKDGVREV	RHOA	156	P61586
FDIVTKGQVCEMTKE	TAX1BP1	516	Q86VP1
CVTSYEMVIKEKSVF	SMARCA1	286	P28370
VYCTEKMSQQVAELG	SYNE1	5596	Q8NF91
CIDAYNETMTEKLVK	TCAF1	126	Q9Y4C2
CAVTMKKYVEENVSQ	SLC9A4	331	Q6AI14
QKVGIMYCKAGQSTE	SIPA1L1	611	O43166
TYCQTIVEKVGMEIN	SEC23IP	546	Q9Y6Y8
VHEVECSYSTSNKMK	ITGAL	631	P20701
YTLKGERTVTCMDNK	SRPX	151	P78539
YTLGQCRQSEKEKME	STK17A	376	Q9UEE5
IQTYLTVCKDVVMVG	NCAPG2	881	Q86XI2
CGQMSEIEAKVRYVK	TLN1	286	Q9Y490
CIKGDQYIVDMANTK	WDR70	266	Q9NW82
TEVVNTMCGYKTIDK	TSPAN15	191	O95858
MYKCVVSNKVGQDER	FLT4	531	P35916
TMVAYGLVECVESKN	UNC93A	421	Q86WB7
SSTKDVIIKGMVCGY	PRSS42P	241	Q7Z5A4
QFREVYVGKETMCTV	TRIM9	486	Q9C026
FYVDSICSVKMEVSK	SLC30A5	286	Q8TAD4
EQAKYVSMTIKGVTS	MYOM2	1396	P54296