Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalmodulin binding

CAMK1D SCN2A SCN3A NGFR CAMK1G GEM MYLK2

9.69e-06230657GO:0005516
GeneOntologyMolecularFunctionsodium ion binding

SCN2A SCN3A SCN9A

1.17e-0514653GO:0031402
GeneOntologyMolecularFunctionmRNA cap binding

EIF4E EIF3D

6.23e-054652GO:0098808
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN2A SCN3A SCN9A

8.11e-0526653GO:0005248
GeneOntologyMolecularFunctionalkali metal ion binding

SCN2A SCN3A SCN9A

8.11e-0526653GO:0031420
GeneOntologyMolecularFunctioncalcium/calmodulin-dependent protein kinase activity

CAMK1D CAMK1G MYLK2

9.11e-0527653GO:0004683
GeneOntologyMolecularFunctionchemorepellent activity

SEMA3A SEMA4D NRG1

1.13e-0429653GO:0045499
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

HOXA10 VAX1 CDX1 GTF2I NKX1-1 ISX GBX2 DLX3 ZNF396 EN2 SP110 DMBX1 LEUTX NKX1-2

1.47e-0414126514GO:0000981
GeneOntologyMolecularFunctiontranslation initiation factor activity

EIF4E EIF3D EIF3G

6.13e-0451653GO:0003743
GeneOntologyMolecularFunctionsodium channel activity

SCN2A SCN3A SCN9A

6.49e-0452653GO:0005272
GeneOntologyCellularComponentchromatin

HOXA10 VAX1 CDX1 USP22 INO80C KDM4C MBD1 NKX1-1 ISX GBX2 DLX3 ZNF396 EN2 DMBX1 LEUTX NKX1-2

1.06e-0514806616GO:0000785
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN2A SCN3A SCN9A

1.98e-0517663GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN2A SCN3A SCN9A

1.04e-0429663GO:0034706
GeneOntologyCellularComponenteukaryotic translation initiation factor 3 complex

EIF3D EIF3G

1.14e-0316662GO:0005852
GeneOntologyCellularComponenteukaryotic 48S preinitiation complex

EIF3D EIF3G

1.45e-0318662GO:0033290
GeneOntologyCellularComponenteukaryotic 43S preinitiation complex

EIF3D EIF3G

1.62e-0319662GO:0016282
GeneOntologyCellularComponenttranslation preinitiation complex

EIF3D EIF3G

1.80e-0320662GO:0070993
GeneOntologyCellularComponentaxon

SEMA3A NRG1 PTPRK FRMD7 SCN2A SCN3A SCN9A NGFR MYLK2

1.86e-03891669GO:0030424
DomainHomeobox_CS

HOXA10 VAX1 CDX1 NKX1-1 ISX GBX2 DLX3 EN2 DMBX1 LEUTX NKX1-2

3.34e-111866411IPR017970
DomainHomeodomain-like

HOXA10 BDP1 VAX1 CDX1 NKX1-1 ISX GBX2 DLX3 EN2 DMBX1 LEUTX DNAJC2 NKX1-2

8.14e-113326413IPR009057
DomainHomeobox

HOXA10 VAX1 CDX1 NKX1-1 ISX GBX2 DLX3 EN2 DMBX1 LEUTX NKX1-2

3.91e-102346411PF00046
DomainHOMEOBOX_1

HOXA10 VAX1 CDX1 NKX1-1 ISX GBX2 DLX3 EN2 DMBX1 LEUTX NKX1-2

4.29e-102366411PS00027
DomainHOMEOBOX_2

HOXA10 VAX1 CDX1 NKX1-1 ISX GBX2 DLX3 EN2 DMBX1 LEUTX NKX1-2

4.90e-102396411PS50071
DomainHomeobox_dom

HOXA10 VAX1 CDX1 NKX1-1 ISX GBX2 DLX3 EN2 DMBX1 LEUTX NKX1-2

4.90e-102396411IPR001356
Domain-

HOXA10 VAX1 CDX1 ISX GBX2 DLX3 EN2 DMBX1 LEUTX DNAJC2 NKX1-2

2.91e-0928364111.10.10.60
DomainHOX

HOXA10 VAX1 CDX1 NKX1-1 ISX GBX2 DLX3 EN2 DMBX1 NKX1-2

7.44e-092376410SM00389
DomainHomeobox_metazoa

HOXA10 CDX1 NKX1-1 GBX2 DLX3 EN2 NKX1-2

2.37e-0890647IPR020479
DomainNa_trans_cytopl

SCN2A SCN3A SCN9A

7.62e-076643PF11933
DomainNa_trans_cytopl

SCN2A SCN3A SCN9A

7.62e-076643IPR024583
DomainNa_channel_asu

SCN2A SCN3A SCN9A

4.53e-0610643IPR001696
DomainNa_trans_assoc

SCN2A SCN3A SCN9A

4.53e-0610643IPR010526
DomainNa_trans_assoc

SCN2A SCN3A SCN9A

4.53e-0610643PF06512
DomainHTH_motif

VAX1 CDX1 DLX3 EN2

9.17e-0569644IPR000047
DomainChannel_four-helix_dom

SCN2A SCN3A SCN9A

9.84e-0457643IPR027359
Domain-

SCN2A SCN3A SCN9A

9.84e-04576431.20.120.350
DomainCa/CaM-dep_Ca-dep_prot_Kinase

CAMK1D CAMK1G MYLK2

1.71e-0369643IPR020636
DomainSemaphorin

SEMA3A SEMA4D

2.11e-0320642IPR027231
DomainIQ

SCN2A SCN3A SCN9A

2.71e-0381643SM00015
DomainPH_dom-like

RASA2 FRMD7 PLEKHA2 PLEKHA6 WDFY4 AFAP1L1

3.34e-03426646IPR011993
DomainIQ_motif_EF-hand-BS

SCN2A SCN3A SCN9A

3.65e-0390643IPR000048
DomainIQ

SCN2A SCN3A SCN9A

4.00e-0393643PS50096
Domainig

SEMA3A SEMA4D NRG1 PTPRK

4.10e-03190644PF00047
DomainImmunoglobulin

SEMA3A SEMA4D NRG1 PTPRK

4.10e-03190644IPR013151
DomainSema

SEMA3A SEMA4D

5.04e-0331642SM00630
DomainSemap_dom

SEMA3A SEMA4D

5.04e-0331642IPR001627
DomainSema

SEMA3A SEMA4D

5.04e-0331642PF01403
DomainSEMA

SEMA3A SEMA4D

5.04e-0331642PS51004
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_CAMK_SIGNALING_PATHWAY

CAMK1D CAMK1G MYLK2

4.15e-0519513M47957
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN2A SCN3A SCN9A

1.87e-0431513M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN2A SCN3A SCN9A

2.05e-0432513M27455
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN2A SCN3A SCN9A

6.53e-09366319284629
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN2A SCN3A SCN9A

6.51e-0856638812438
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN2A SCN3A SCN9A

1.30e-07666323652591
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN2A SCN3A SCN9A

5.44e-07966316382098
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

HOXA10 VAX1 CDX1 ISX GBX2 DLX3 ZNF396 EN2 DMBX1

8.80e-0754466928473536
Pubmed

A census of human transcription factors: function, expression and evolution.

VAX1 CDX1 ISX GBX2 DLX3 ZNF396 EN2 SP110 DMBX1 LEUTX DNAJC2

1.05e-06908661119274049
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN2A SCN3A SCN9A

1.84e-061366315123669
Pubmed

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

RPL29 GTF2I DDX54 NOL7 EIF3D EIF3G CTPS1 NACA4P DNAJC2

3.37e-0664166936057605
Pubmed

Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.

SCN2A SCN3A

3.55e-06266220346423
Pubmed

Candidate gene analysis of semaphorins in patients with Alzheimer's disease.

SEMA3A SEMA4D

3.55e-06266219957197
Pubmed

Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.

SCN2A SCN3A

3.55e-06266211245985
Pubmed

Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.

SCN2A SCN3A

3.55e-06266223016767
Pubmed

Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.

SCN2A SCN3A

3.55e-06266227153334
Pubmed

Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.

SCN3A SCN9A

3.55e-06266225172946
Pubmed

Do DLX3 and CD271 Protect Human Keratinocytes from Squamous Tumor Development?

NGFR DLX3

3.55e-06266231331058
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

BDP1 NRG1 PPP1R12A DDX54 SCN9A CTPS1 NACA4P MAP3K4

4.57e-0649766836774506
Pubmed

Modulation of semaphorin3A activity by p75 neurotrophin receptor influences peripheral axon patterning.

SEMA3A NGFR

1.06e-05366218032673
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN2A SCN3A

1.06e-05366212610651
Pubmed

Brain-derived neurotrophic factor signaling is altered in the forebrain of Engrailed-2 knockout mice.

NGFR EN2

1.06e-05366226987954
Pubmed

Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).

SCN3A SCN9A

1.06e-05366233895391
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN2A SCN3A

1.06e-05366223859570
Pubmed

Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia.

SCN3A SCN9A

1.06e-05366219699781
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN2A SCN3A

1.06e-05366218784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN2A SCN3A

1.06e-05366217544618
Pubmed

Trans-ethnic meta-analysis of genome-wide association studies for Hirschsprung disease.

SEMA3A NRG1

1.06e-05366227702942
Pubmed

Identification of functional voltage-gated Na(+) channels in cultured human pulmonary artery smooth muscle cells.

SCN2A SCN3A

1.06e-05366216052353
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN2A SCN3A

1.06e-05366214973256
Pubmed

Population variation in total genetic risk of Hirschsprung disease from common RET, SEMA3 and NRG1 susceptibility polymorphisms.

SEMA3A NRG1

1.06e-05366225666438
Pubmed

Autocrine Semaphorin3A stimulates eukaryotic initiation factor 4E-dependent RhoA translation in breast tumor cells.

SEMA3A EIF4E

1.06e-05366220655307
Pubmed

Cumulative Risk Impact of RET, SEMA3, and NRG1 Polymorphisms Associated With Hirschsprung Disease in Han Chinese.

SEMA3A NRG1

1.06e-05366227203398
Pubmed

Multiple, independent, common variants at RET, SEMA3 and NRG1 gut enhancers specify Hirschsprung disease risk in European ancestry subjects.

SEMA3A NRG1

1.06e-05366234006365
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

HOXA10 ISX GBX2 EN2 DMBX1 NKX1-2

1.10e-0526366620932939
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN2A SCN3A

2.12e-05466217537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN2A SCN3A

2.12e-05466235031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN2A SCN3A

2.12e-05466229578003
Pubmed

Semaphorin 3A is required for guidance of olfactory axons in mice.

SEMA3A NGFR

2.12e-05466211027230
Pubmed

eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.

EIF3D EIF3G

2.12e-05466227462815
Pubmed

Spatiotemporal expression of four isoforms of Ca2+/calmodulin-dependent protein kinase I in brain and its possible roles in hippocampal dendritic growth.

CAMK1D CAMK1G

2.12e-05466217056143
Pubmed

Expression Levels of Semaphorins 3A, 3B, 4A, and 4D on Human Peri-implantitis.

SEMA3A SEMA4D

2.12e-05466229763494
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN2A SCN3A

2.12e-05466235801810
Pubmed

A functional coupling between CRMP1 and Nav1.7 for retrograde propagation of Semaphorin3A signaling.

SEMA3A SCN9A

2.12e-05466228254884
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN2A SCN3A

2.12e-0546628974318
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

RPL29 GTF2I VRK3 PPP1R12A EIF4E EIF3D EIF3G CTPS1 PKD1L3 NACA4P AFAP1L1

2.77e-051284661117353931
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN2A SCN3A

3.53e-0556621679748
Pubmed

Balding: a new mutation on mouse chromosome 18 causing hair loss and immunological defects.

CDX1 DSG3

3.53e-0556628182278
Pubmed

Isx participates in the maintenance of vitamin A metabolism by regulation of beta-carotene 15,15'-monooxygenase (Bcmo1) expression.

CDX1 ISX

3.53e-05566218093975
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN3A SCN9A

3.53e-05566222875929
Pubmed

Isoform-specific expression and function of neuregulin.

NRG1 NGFR

3.53e-0556629342050
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN2A SCN3A

3.53e-05566217724025
Pubmed

RASD2, MYH9, and CACNG2 genes at chromosome 22q12 associated with the subgroup of schizophrenia with non-deficit in sustained attention and executive function.

APOL6 EIF3D

3.53e-05566218571626
Pubmed

Comprehensive comparative homeobox gene annotation in human and mouse.

CDX1 GBX2

3.53e-05566226412852
Pubmed

Further characterisation of the translational termination-reinitiation signal of the influenza B virus segment 7 RNA.

EIF3D EIF3G

3.53e-05566221347434
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN2A SCN3A

3.53e-05566224337656
Pubmed

Emx2 homeodomain transcription factor interacts with eukaryotic translation initiation factor 4E (eIF4E) in the axons of olfactory sensory neurons.

EIF4E EN2

3.53e-05566215247416
Pubmed

Protein microarrays for the identification of praja1 e3 ubiquitin ligase substrates.

GTF2I DDX54 CAMK1G

3.74e-053466321461837
Pubmed

Age-related changes in the expression of schizophrenia susceptibility genes in the human prefrontal cortex.

NRG1 NGFR

5.29e-05666218470533
Pubmed

Murine Otx1 and Drosophila otd genes share conserved genetic functions required in invertebrate and vertebrate brain development.

GBX2 EN2

5.29e-0566629521907
Pubmed

Organization, sequence, chromosomal localization, and promoter identification of the mouse orphan nuclear receptor Nurr1 gene.

SCN3A SCN9A

5.29e-0566629143501
Pubmed

Short- and long-range attraction of cortical GABAergic interneurons by neuregulin-1.

SEMA3A NRG1

5.29e-05666215473965
Pubmed

The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles.

NRG1 EN2

7.40e-05766210625539
Pubmed

Effects of different regions of the developing gut on the migration of enteric neural crest-derived cells: a role for Sema3A, but not Sema3F.

SEMA3A NGFR

7.40e-05766217362911
Pubmed

Pain without nociceptors? Nav1.7-independent pain mechanisms.

SCN3A SCN9A

7.40e-05766224440715
Pubmed

Plexin-A3 and plexin-A4 restrict the migration of sympathetic neurons but not their neural crest precursors.

SEMA3A NGFR

7.40e-05766218262512
Pubmed

CD24 is expressed by myofiber synaptic nuclei and regulates synaptic transmission.

NRG1 MYLK2

9.86e-05866216606832
Pubmed

Role of Hoxa-2 in axon pathfinding and rostral hindbrain patterning.

EN2 NKX1-2

9.86e-0586629367425
Pubmed

Neuropilin receptors guide distinct phases of sensory and motor neuronal segmentation.

SEMA3A NGFR

9.86e-05866219403658
Pubmed

Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root ganglia.

SEMA3A NGFR

9.86e-05866219386662
Pubmed

EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region.

GBX2 EN2

9.86e-05866211124114
Pubmed

Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly.

EIF3D EIF3G

9.86e-0586629341143
Pubmed

Significant determinants of mouse pain behaviour.

SCN3A SCN9A

9.86e-05866225101983
Pubmed

Classification and nomenclature of all human homeobox genes.

VAX1 LEUTX

9.86e-05866217963489
Pubmed

TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.

SEMA3A SEMA4D NGFR

9.97e-054766335462405
Pubmed

SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.

RPL29 GTF2I DDX54 EIF3D CTPS1

1.05e-0424566535652658
Pubmed

Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNA.

EIF4E EIF3D EIF3G

1.13e-044966324248602
Pubmed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

SEMA3A SEMA4D NRG1 NGFR DLX3

1.17e-0425166529031500
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

RPL29 GTF2I DSG3 PPP1R12A DDX54 EIF3D EIF3G CTPS1 DNAJC2 AFAP1L1

1.23e-041257661036526897
Pubmed

The sensory innervation of the mouse spinal cord may be patterned by differential expression of and differential responsiveness to semaphorins.

SEMA3A SEMA4D

1.27e-0496628812066
Pubmed

The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170.

EIF3D EIF3G

1.27e-0496628995410
Pubmed

Genetic subdivision of the tectum and cerebellum into functionally related regions based on differential sensitivity to engrailed proteins.

GBX2 EN2

1.27e-04966217537797
Pubmed

ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2-and heregulin-deficient mice.

NRG1 EN2

1.27e-0496629362461
Pubmed

Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.

SEMA3A RASA2

1.27e-04966222210626
Pubmed

Cardia bifida, defective heart development and abnormal neural crest migration in embryos lacking hypoxia-inducible factor-1alpha.

SEMA3A NGFR

1.27e-04966214659802
Pubmed

Genetic mapping of the peripheral sodium channel genes, Scn9a and Scn10a, in the mouse.

SCN3A SCN9A

1.27e-0496628854872
Pubmed

The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system.

NRG1 NGFR

1.27e-0496629637684
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN2A SCN3A

1.27e-04966215746173
Pubmed

The duration of Fgf8 isthmic organizer expression is key to patterning different tectal-isthmo-cerebellum structures.

GBX2 EN2

1.27e-04966219793884
Pubmed

Detection of homeobox genes in development and evolution.

HOXA10 GBX2

1.27e-0496621720547
Pubmed

A new GFP-tagged line reveals unexpected Otx2 protein localization in retinal photoreceptors.

GBX2 EN2

1.27e-04966217980036
Pubmed

Regulation of Hoxb3 expression in the hindbrain and pharyngeal arches by rae28, a member of the mammalian Polycomb group of genes.

CDX1 NGFR

1.27e-04966211044623
Pubmed

Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3' untranslated region.

EIF4E EIF3D EIF3G

1.43e-045366312588972
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

HOXA10 RPL29 GTF2I VRK3 INO80C MBD1 DDX54 NOL7 NCAPH2 SP110

1.56e-041294661030804502
Pubmed

FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate.

GBX2 EN2

1.58e-041066210518499
Pubmed

mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis.

EIF4E EIF3G

1.58e-041066230232453
Pubmed

Conservation and diversity of eukaryotic translation initiation factor eIF3.

EIF3D EIF3G

1.58e-04106628995409
Pubmed

Molecular neurobiology of mTOR.

GBX2 DMBX1

1.58e-041066227889578
Pubmed

Neuropilin 1 signaling guides neural crest cells to coordinate pathway choice with cell specification.

SEMA3A NGFR

1.58e-041066219325129
Pubmed

NEDDylation promotes stress granule assembly.

EIF4E EIF3G

1.58e-041066227381497
Pubmed

Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2.

GBX2 DMBX1

1.58e-041066211731459
Pubmed

Signaling through retinoic acid receptors is essential for mammalian uterine receptivity and decidualization.

HOXA10 CDX1 GBX2

1.60e-045566334292881
Pubmed

NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system.

SEMA3A NGFR

1.93e-041166222790009
InteractionEN2 interactions

HOXA10 EIF4E EN2

1.14e-0514653int:EN2
CytobandEnsembl 112 genes in cytogenetic band chr2q24

SCN2A SCN3A SCN9A TTC21B

3.74e-05127674chr2q24
Cytoband2q24

SCN3A SCN9A

1.14e-04116722q24
Cytoband2q24.3

SCN2A TTC21B

2.48e-04166722q24.3
CytobandEnsembl 112 genes in cytogenetic band chr18q12

INO80C DSG3 ZNF396

4.87e-04104673chr18q12
Cytoband22q12.3

APOL6 ISX

1.08e-033367222q12.3
Cytoband5q32

CDX1 AFAP1L1

2.86e-03546725q32
CytobandEnsembl 112 genes in cytogenetic band chr22q12

APOL6 ISX EIF3D

4.98e-03235673chr22q12
CytobandEnsembl 112 genes in cytogenetic band chr5q32

CDX1 AFAP1L1

6.16e-0380672chr5q32
GeneFamilyNKL subclass homeoboxes and pseudogenes

VAX1 NKX1-1 DLX3 EN2 NKX1-2

1.12e-0667505519
GeneFamilySodium voltage-gated channel alpha subunits

SCN2A SCN3A SCN9A

1.65e-0695031203
GeneFamilyHOXL subclass homeoboxes

HOXA10 CDX1 GBX2

4.00e-0452503518
GeneFamilyEukaryotic translation initiation factor 3

EIF3D EIF3G

5.73e-04135021121
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA3A SEMA4D

1.38e-0320502736
GeneFamilyPRD class homeoboxes and pseudogenes

ISX DMBX1 LEUTX

2.10e-0392503521
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RASA2 PLEKHA2 PLEKHA6 AFAP1L1

2.50e-03206504682
CoexpressionGSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_3H_DN

CAPG EIF4E NOL7 PIR GEM MAP3K4

1.14e-05200666M9950
ToppCellFetal_29-31_weeks-Immune-B_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CAMK1D SCN3A PPP1R16B PLEKHA2 SP110 WDFY4

4.22e-07190676424550418c1bd4eb070cf3c41cf09fa9d89aef37
ToppCellFetal_29-31_weeks-Immune-B_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CAMK1D SCN3A PPP1R16B PLEKHA2 SP110 WDFY4

4.35e-0719167684452125d1b5b76974e3f9126f611eff16d45c25
ToppCellCOVID_non-vent-Lymphocytic-B_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

CAMK1D PTPRK SCN3A PPP1R16B PLEKHA2 WDFY4

4.63e-0719367632d139f922cd19adc1cc1e0e9a828115be9945d6
ToppCellCOVID_non-vent-Lymphocytic-B_cell-|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

CAMK1D PTPRK SCN3A PPP1R16B PLEKHA2 WDFY4

4.63e-0719367691955c3773c9729a96e82f240f06b072367970d9
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-FCRL4+_Memory_B|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RPL29 CAPG PPP1R16B SP110 WDFY4

6.87e-061766758c5218aa188ea5a4d3c749b3c8a6596835cbdc87
ToppCellCOVID-19-B_cells-Activated_B_cells|COVID-19 / group, cell type (main and fine annotations)

CAMK1D SCN3A PPP1R16B SP110 WDFY4

7.06e-06177675653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

SEMA3A SCN3A PPP1R16B PKD1L3 AFAP1L1

7.25e-06178675c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEMA3A SCN3A SCN9A PKD1L3 AFAP1L1

7.25e-06178675ad3de3e03a401dac64431a541899445262246347
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-1|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAMK1D PTPRK SCN3A PLEKHA2 WDFY4

7.87e-061816756df40f86c569b6ecfc3137a68d1355b012dbf6bf
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

CAMK1D PTPRK SCN3A PLEKHA2 WDFY4

8.98e-06186675f352c63666273defea3e57ba3a3bfad52c4ea65b
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CAMK1D PTPRK SCN3A PLEKHA2 WDFY4

8.98e-06186675e2d265003aaea1acaf618d3f102c9933c19102e6
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEMA3A SCN3A SCN9A PKD1L3 AFAP1L1

8.98e-0618667520340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAMK1D PTPRK SCN3A PLEKHA2 WDFY4

9.21e-06187675e7970ec1507adfa91a296489166142cb9400421f
ToppCellImmune-B_cell|World / Lineage, Cell type, age group and donor

CAMK1D PPP1R16B PLEKHA2 SP110 WDFY4

9.21e-06187675795690c6306c366e733279491138d0cd9b469b21
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SEMA3A SCN3A PPP1R16B MYLK2 AFAP1L1

9.70e-061896750d18ea72bd58d32a8ab9a61cf97f5786642f804b
ToppCellCOVID_vent-Lymphocytic-B_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

CAMK1D PTPRK SCN3A PLEKHA2 WDFY4

9.95e-0619067540b5e9e8f8fd8d84cb5b43e67b49267082348e9f
ToppCellCOVID_vent-Lymphocytic-B_cell-|COVID_vent / Disease condition, Lineage, Cell class and subclass

CAMK1D PTPRK SCN3A PLEKHA2 WDFY4

9.95e-06190675a37a32dc1b931562a6660074e19d5598efc65284
ToppCellCOVID-19-lung-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SEMA3A INO80C SCN3A SCN9A AFAP1L1

1.05e-05192675cbe57cda44232b183821ac633b60a2668265e616
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B-Naive_B_cells|lymph-node_spleen / Manually curated celltypes from each tissue

CAMK1D PTPRK SCN3A PLEKHA2 WDFY4

1.10e-0519467520967afbadb3cf80ba9f4d7ebda4e64389252e70
ToppCellTracheal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA3A SCN3A PPP1R16B PKD1L3 AFAP1L1

1.16e-0519667509a7edf4a7defb7fe70d9777dd9500ee8421ff31
ToppCellTracheal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA3A SCN3A PPP1R16B PKD1L3 AFAP1L1

1.16e-05196675e50d2c66d5c5cd25fdfecdcc4c8506a1d0a85755
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CAMK1D PPP1R16B PLEKHA2 SP110 WDFY4

1.19e-05197675da61afba697ec49ca86e062d35a825280da558ac
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SEMA3A SCN3A SCN9A PPP1R16B AFAP1L1

1.27e-05200675f99d0d3f51b4893fa7898c5b435494358a654cbd
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SEMA3A SCN3A SCN9A PPP1R16B AFAP1L1

1.27e-05200675e65d4ae3d48f68c12edd5dc2c2f4e25e4acfadf1
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Lymphatic|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

SEMA3A SCN3A SCN9A PPP1R16B AFAP1L1

1.27e-052006754ec8e30dd241d83a1bba1c5967b6a4656afbfafd
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer|World / Primary Cells by Cluster

BDP1 PTPRK SCN2A SCN3A SCN9A

1.27e-05200675db10f76938af553d1a2275bb02ef75dff3c3135b
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer-21|World / Primary Cells by Cluster

BDP1 PTPRK SCN2A SCN3A SCN9A

1.27e-0520067530a3e4aee12ec1b5acdce90f86c9733c27a7f6fc
ToppCellCOVID-19-COVID-19_Convalescent-Lymphocyte-B-B_naive|COVID-19_Convalescent / Disease, condition lineage and cell class

CAMK1D PTPRK SCN3A PLEKHA2 WDFY4

1.27e-052006755c1b51b9571681d8b792d1443d9f8926dcd55b29
ToppCellCTRL-Lymphoid-pDC|CTRL / Disease state, Lineage and Cell class

SCN3A SCN9A PPP1R16B NGFR

5.75e-05139674bbc10812b0c5b8c85e78171c12316becde8895c3
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA10 SEMA4D NRG1 EN2

6.96e-05146674669001b772b6d6109a09727619ed5829122b48db
ToppCellIPF-Epithelial-PNEC|IPF / Disease state, Lineage and Cell class

NRG1 SCN2A SCN3A ISX

9.68e-05159674adec82df944fe8699a69ca52534353bef100f2f9
ToppCellIPF-Epithelial-PNEC|World / Disease state, Lineage and Cell class

NRG1 SCN2A SCN3A ISX

1.02e-04161674133833729ba8b6d3eef326590ca7476b17602cbb
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPRK SCN3A PLEKHA2 WDFY4

1.12e-04165674fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-B_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CAMK1D PPP1R16B SP110 WDFY4

1.12e-041656747039bb5a7af4684fbd1192230864e5cd6936e83c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-B_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CAMK1D PPP1R16B SP110 WDFY4

1.12e-04165674d2c79653710b139794170f3d72f11392fc548ac7
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|356C / Donor, Lineage, Cell class and subclass (all cells)

SEMA3A SCN3A MYLK2 AFAP1L1

1.14e-041666745ba45407a47207ff01e4a3f9f5d91d8247fe9b6f
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|356C / Donor, Lineage, Cell class and subclass (all cells)

SEMA3A SCN3A MYLK2 AFAP1L1

1.14e-041666746bd5aa205b6e4b88ba9f8cd0999e2191d7d1d16c
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

HOXA10 SCN3A SCN9A MYLK2

1.17e-04167674cb396f3edb9e8fdc316091e8e193dbba50e0be0c
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-CD45____B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPG PLEKHA2 SP110 GEM

1.22e-04169674d44fc49056799dfc70a3c7d538c210d88ffded05
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3A PPP1R16B MYLK2 AFAP1L1

1.25e-041706746035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CAMK1D PPP1R16B SP110 WDFY4

1.25e-04170674a965e3ee6818790a4a6916824fde64333d9b11b7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3A PPP1R16B MYLK2 AFAP1L1

1.25e-04170674c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3A PPP1R16B MYLK2 AFAP1L1

1.25e-04170674dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPG PLEKHA2 SP110 GEM

1.25e-0417067453fd50c9a27d47662fbcbd7e9e9837f72ac448c5
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA3A HOXA10 NRG1 GEM

1.25e-04170674a7184dc41f90caa753860ed0f65a18133f84bc5f
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-CD45____B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPG NGFR PLEKHA2 WDFY4

1.25e-041706746210ee3bf29059e6149c047bb7e02c5f59441519
ToppCellCOVID-19-kidney-Bcells|COVID-19 / Disease (COVID-19 only), tissue and cell type

CAMK1D PPP1R16B SP110 WDFY4

1.28e-041716748e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPRK SCN3A PLEKHA2 WDFY4

1.43e-04176674ad05dd934f4ac2e656b3455de091f4c8772de6c8
ToppCellfacs-Trachea-24m-Hematologic-lymphocytic-B_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPP1R16B PLEKHA2 SP110 WDFY4

1.43e-04176674318dc722b95e269002fb01a0feb91c0c8539e150
ToppCellfacs-Trachea-24m-Hematologic-lymphocytic-B_cell-B_cell_of_the_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPP1R16B PLEKHA2 SP110 WDFY4

1.43e-04176674f6891006d816309edabe75b2abf60675f2958e55
ToppCellControl-B_cells-B_cells|Control / group, cell type (main and fine annotations)

PPP1R16B PLEKHA2 SP110 WDFY4

1.43e-04176674d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3A SCN9A PPP1R16B AFAP1L1

1.46e-04177674c274fbdc141855ff4581d437d4997c64cc193278
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-B_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CAMK1D PPP1R16B SP110 WDFY4

1.46e-04177674b07e6139618d888a9fd7cf43cad0d86a3f63e09e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3A SCN9A PPP1R16B AFAP1L1

1.46e-04177674f5e6df5cafd003bbfbb3b634ee58d0b1e2be5cc7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3A SCN9A PPP1R16B AFAP1L1

1.46e-04177674c8a51e480b978dc0ded85583261f2c892e085be8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-B_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CAMK1D PPP1R16B SP110 WDFY4

1.46e-041776746376ec12322c04d5d37ec2fdc376700464cbc7fb
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-Zbtb32+_B_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPP1R16B NGFR WDFY4 GEM

1.56e-04180674c12c1cc206f7e63e5722471bd3eb84caddb84129
ToppCellChildren_(3_yrs)-Immune-B_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CAMK1D PPP1R16B SP110 WDFY4

1.56e-0418067440a12eb852373ae3d7c8d9bca376b0ae99f724b3
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPP1R16B NGFR WDFY4 GEM

1.56e-04180674d8135f73a89b97168f2048258f4648e23536ece4
ToppCellCOVID-19-kidney-Bcells|kidney / Disease (COVID-19 only), tissue and cell type

CAMK1D PPP1R16B SP110 WDFY4

1.56e-041806745650fc7ebcdf5e0be9a217a58d36a8386d59fd1b
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CAMK1D SCN3A PPP1R16B WDFY4

1.59e-0418167451e4d6bfdbf414d8e30aee2e6f7492f4f7f54373
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CAPG NOL7 SP110 WDFY4

1.59e-04181674d909821355f4bc9e35387cda6ecf7c56793d9da4
ToppCellCOPD-Epithelial-Basal|World / Disease state, Lineage and Cell class

NRG1 PTPRK NGFR CAMK1G

1.59e-041816746d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CAPG NOL7 SP110 WDFY4

1.59e-0418167452935c496b45207a173b5ac7812f46210c3f74b0
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTPRK SCN3A PLEKHA2 WDFY4

1.59e-041816740c52dd82e6b3dce3d6bb5c13501bf8383f7121e4
ToppCellB_cells-Naive_B_cells_|World / Immune cells in Kidney/Urine in Lupus Nephritis

PTPRK SCN3A PLEKHA2 WDFY4

1.63e-0418267463c3b63315276b66667d49fab09661ac320e7a36
ToppCelldroplet-Limb_Muscle-nan-24m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R16B PLEKHA2 SP110 WDFY4

1.63e-041826746946ab8d91fb8dce5af065f57a13659b8d97ed5c
ToppCellremission-B_naive|World / disease stage, cell group and cell class

PTPRK SCN3A PLEKHA2 WDFY4

1.63e-04182674cc1dfd2de35aee1a26f7efd78e108b60a3556ec5
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEMA3A SCN3A SCN9A AFAP1L1

1.63e-0418267453c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX54 CAMK1G PLEKHA6 DMBX1

1.66e-04183674bc24145855bf4d027a8058bf92bc796c10f241bb
ToppCellremission-B_naive|remission / disease stage, cell group and cell class

PTPRK SCN3A PLEKHA2 WDFY4

1.66e-04183674280d55d67f1d44594206da2f3a332c9d799dbdf0
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R16B PLEKHA2 SP110 WDFY4

1.66e-04183674544939a0bfef082d361d88ef70d6f0923b8d9af9
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R16B PLEKHA2 SP110 WDFY4

1.66e-0418367420f7b6ec2462032eda957a893ca76d5a5a01333d
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX54 CAMK1G PLEKHA6 DMBX1

1.66e-041836744c325ee6da070513097a11445ec95b0415ffd8a2
ToppCellfacs-BAT-Fat-18m-Lymphocytic-B_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPG PPP1R16B PLEKHA2 SP110

1.70e-04184674fd72663bf990266da2fba70d4f2260f8d48067ee
ToppCell(6)_Endothelial-F_(Lymphatics)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SEMA3A SCN3A MYLK2 AFAP1L1

1.70e-0418467403ea613e00b45c81b752c14505a0538d698f551e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CAMK1D PPP1R16B SP110 WDFY4

1.70e-04184674f81209e6bc01a0140f4487aa8b22eb02fbf0c39c
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Zbtb32+_B_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CAPG NGFR SP110 WDFY4

1.73e-041856745fd4a3776259c96cf2dcb87f050af8226acbbda9
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

SEMA3A SCN3A SCN9A AFAP1L1

1.73e-041856744a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellfacs-Brain_Non-Myeloid-Cerebellum|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRG1 SCN2A EN2 WDFY4

1.73e-04185674c083a4974590b9ed3ecafedd3e9cdebc5047fe39
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

SEMA3A SCN3A SCN9A AFAP1L1

1.73e-0418567436ce23893915f5c380cca39b2c33a516edf31c3a
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CAPG NGFR SP110 WDFY4

1.73e-041856744c55fa96877ab9a00fcbec3fb70fd2208d222527
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEMA3A SCN3A SCN9A AFAP1L1

1.77e-0418667440070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCellCOVID_vent-Myeloid-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

CAPG SCN9A PLEKHA6 WDFY4

1.77e-0418667463a5cdd3f60681762a218be32db84be8f29b88fd
ToppCellChildren_(3_yrs)-Immune-B_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CAMK1D PPP1R16B SP110 WDFY4

1.77e-04186674aa576748921a318798b911a611f05319b95e8d5e
ToppCellCOVID_vent-Myeloid-Dendritic-cDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

CAPG SCN9A PLEKHA6 WDFY4

1.77e-0418667439457a7b43537f2c3e221f9375c95d4515424d7d
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA3A HOXA10 NRG1 GEM

1.77e-04186674360c3e9e5c3a943e68e6939b4a47821bfc75b553
ToppCellCOVID-19_Convalescent-Lymphoid_B-B_naive|COVID-19_Convalescent / Disease group, lineage and cell class

PTPRK SCN3A PLEKHA2 WDFY4

1.77e-041866749d339f57036d17572882ebb801f2be9b1d1ddc1c
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA3A HOXA10 SEMA4D NRG1

1.77e-041866748ea708070166c858cd9bd871670655b0114c32a5
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PPP1R16B GBX2 MYLK2 AFAP1L1

1.81e-0418767429b2e2be26a9d72b154760e47acf61cfe2f45fa7
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTPRK SCN3A PLEKHA2 WDFY4

1.81e-04187674d01926be1c8846a25fb6706e26b56b808b69f8f0
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA3A HOXA10 NRG1 GEM

1.81e-0418767439756ab418267151d86f9c2553db859f71900bb1
ToppCelldroplet-Marrow-nan-21m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R16B PLEKHA2 NOL7 GEM

1.84e-041886742c4432cada1273d08cbdc2824922cf578e448ec8
ToppCellEndothelial-endothelial_cell_of_lymph_vessel|World / Lineage, Cell type, age group and donor

SEMA3A SCN3A PPP1R16B AFAP1L1

1.84e-0418867480910dcbb51990f2baed240f319456c0d3fa2065
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SEMA3A SCN3A PPP1R16B AFAP1L1

1.84e-041886742db80767903703e7e0a1a37c598f7877a909ee94
ToppCellCOVID-19-lung-Lymphatic_EC|lung / Disease (COVID-19 only), tissue and cell type

SEMA3A SCN3A SCN9A AFAP1L1

1.88e-04189674c8db9aaf54ea3cc96c4a2f777c3389e0f31f67f3
ToppCellCTRL-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

CAMK1D PPP1R16B SP110 WDFY4

1.88e-0418967414f3a8c0f4f057ad4e6839b4c3eeaf956d6dc92e
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SEMA3A SCN3A PPP1R16B AFAP1L1

1.88e-0418967455a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCellwk_15-18-Hematologic_Lymphocytic-B-Immature_B|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CAMK1D CAPG PLEKHA2 SP110

1.88e-041896745776f842b3047d21ccdc44db884bfd210823c7da
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTPRK SCN3A PLEKHA2 WDFY4

1.92e-04190674112706d64ee73b55dcf76f33ca064ab1fc6ce87f
DrugZonisamide

SCN2A SCN3A SCN9A

1.47e-0517653DB00909
DrugScorpion Venoms

SCN2A SCN3A SCN9A

1.76e-0518653ctd:D012604
Drug6-Hydroxytropinone [5932-53-6]; Down 200; 25.8uM; MCF7; HT_HG-U133A

ALMS1 RASA2 MBD1 DDX54 SP110 HEXIM1

2.04e-051966567346_DN
DrugProcaine hydrochloride [51-05-8]; Up 200; 14.6uM; MCF7; HT_HG-U133A

SEMA4D CDX1 KDM4C CAPG NCAPH2 SP110

2.29e-052006561674_UP
DrugN-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide

SCN3A SCN9A

2.40e-053652ctd:C561228
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN2A SCN3A SCN9A

1.21e-0610653DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN2A SCN3A SCN9A

1.21e-0610653DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN2A SCN3A SCN9A

2.21e-0612653DOID:0060170 (implicated_via_orthology)
Diseaseanxiety disorder (implicated_via_orthology)

SCN2A SCN3A SCN9A

1.52e-0522653DOID:2030 (implicated_via_orthology)
Diseaseartificially sweetened beverage consumption measurement

KDM4C NKX1-1

7.13e-056652EFO_0010096
Diseaseautistic disorder (is_implicated_in)

KDM4C EIF4E EN2

1.10e-0442653DOID:12849 (is_implicated_in)
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN2A SCN9A

1.70e-049652C3502809
Diseaseautism spectrum disorder (implicated_via_orthology)

VRK3 SCN2A EIF4E EN2

3.59e-04152654DOID:0060041 (implicated_via_orthology)
DiseaseInfantile Severe Myoclonic Epilepsy

SCN2A SCN9A

3.67e-0413652C0751122
Diseasediabetic neuropathy (biomarker_via_orthology)

NRG1 NGFR

6.36e-0417652DOID:9743 (biomarker_via_orthology)
Diseasecolorectal cancer, inflammatory bowel disease

ALMS1 SP110

7.98e-0419652EFO_0003767, MONDO_0005575
Diseasealpha-tocopherol measurement

KDM4C SCN3A

8.85e-0420652EFO_0007898
Diseasevisual epilepsy (biomarker_via_orthology)

NRG1 MBD1 NGFR

1.05e-0390653DOID:11832 (biomarker_via_orthology)
Diseasetuberculosis (is_implicated_in)

NRG1 SP110

1.74e-0328652DOID:399 (is_implicated_in)
Diseaseage at menarche

SEMA4D GTF2I ALMS1 PTPRK KDM4C SCN2A

1.96e-03594656EFO_0004703

Protein segments in the cluster

PeptideGeneStartEntry
FNKARKDRDWGQNAL

TTC21B

1046

Q7Z4L5
KTNGWRIDKAFQEKR

BDP1

346

A6H8Y1
WFQNRRAKERKVNKK

CDX1

201

P47902
VARRKNWKKFGNSEF

EIF3G

96

O75821
AKKNVRAFWKLRANP

APOL6

181

Q9BWW8
KEWSGRQQQRNKLQK

ALMS1

3661

Q8TCU4
KRKLRKQHGNGKRNW

BRWD3

1651

Q6RI45
NKNKKNWDKARERFT

AGGF1

676

Q8N302
TQVKIWFQNRRSKFK

DLX3

171

O60479
FERNSRWSNKKNVPK

DNAJC2

186

Q99543
QNQRAKWRKQEKIGN

ISX

131

Q2M1V0
AQRLKQRGINKSWKE

MSANTD5

71

A0A3B3IT52
QGRTRIGKKNFKKRW

RASA2

616

Q15283
ARRFWGKIVAKNNKN

GEM

266

P55040
LRFKWFKNGNELNRK

NRG1

66

Q02297
QQAKRRQKREWVKFA

DSG3

41

P32926
VWVNDFSRAKKANKR

NEIL2

141

Q969S2
GNTKINTFNWAKIRK

FRMD7

216

Q6ZUT3
KNKRGGRWLITLNKQ

EIF4E

106

P06730
KWDRKKKRFVGQSGQ

DDX54

731

Q8TDD1
WGQQQRQLGKKKHRR

HEXIM1

141

O94992
KFGGSNQKRQKCRWR

MBD1

361

Q9UIS9
KRRWKKNFIAVSAAN

MYLK2

566

Q9H1R3
FRNAKNGFERAKTWK

PIR

271

O00625
RGGALKQTKNNKWAH

KDM4C

761

Q9H3R0
NAANWLTAKSGRKKR

HOXA10

326

P31260
KWLLKGKLRNQRNQN

MEIOSIN

51

C9JSJ3
QKNFAKSKWRQAFNA

CAMK1G

296

Q96NX5
NAWGIQKKQNAKRFK

NOL7

231

Q9UMY1
AQKRRAQQLKKWAQY

PPP1R16B

26

Q96T49
AVAGKKNRTWKNLKQ

INO80C

96

Q6PI98
QNRRAKWKRVKAGNA

GBX2

296

P52951
GWENAALFLNRKRKQ

DSCR9

96

P59020
QVWFKNRRAKFRKKQ

DMBX1

116

Q8NFW5
LQKKFQKQFGVRQKW

EIF3D

136

O15371
WKGRKANEKERQAAL

CAPG

296

P40121
WFQNKRAKIKKATGN

EN2

291

P19622
AGKRKVREFNFEKWN

GTF2I

341

P78347
SWDVAKKDQNRAKNR

PTPRK

901

Q15262
LRKVTFKWQRGNKIG

MAP3K4

1336

Q9Y6R4
NQSRKWHRNGIKKPR

RPL29

11

P47914
VKQGNVRKSWKRRFF

PLEKHA2

206

Q9HB19
NRRTKWKKQNPGADT

NKX1-1

346

Q15270
FQNRRTKWKKQNPGA

NKX1-2

211

Q9UD57
CQLKQQKWRFFTGKR

PKD1L3

1486

Q7Z443
RWKNLKVNFDNVGLG

SCN9A

1381

Q15858
KIQAIAWARNQKKPF

CTPS1

381

P17812
ALGKQARWKNVKVNF

SCN3A

1386

Q9NY46
KAWKADRAGNVIFRK

OXCT1

211

P55809
KWKHLQENKKGRNRR

SEMA3A

746

Q14563
NLARVFWKFQNGVLK

SEMA4D

581

Q92854
GKGRNAKNWKRNIRC

SP110

506

Q9HB58
QIRKNFAKSKWRQAF

CAMK1D

296

Q8IU85
FLLRKKRFGQWAKQL

AFAP1L1

226

Q8TED9
RKRKGAAKLQDFHQW

NCAPH2

351

Q6IBW4
LFKQASSGVKQWNKR

PLEKHA6

66

Q9Y2H5
LGSFKVDNWKQNLRA

USP22

26

Q9UPT9
AFKRWNSCKQNKQGA

NGFR

271

P08138
ARWKNVKVNFDNVGL

SCN2A

1396

Q99250
VQRRKCGNIKAANAW

WDFY4

2246

Q6ZS81
NFFQRAAKPLQVNKW

VRK3

216

Q8IV63
GRFEKRQGNPSWKKQ

ZNF396

236

Q96N95
RKFKWGKGFLDLNRQ

TSR3

186

Q9UJK0
VWFQNRRTKQKKDQG

VAX1

146

Q5SQQ9
FKNQRAKWKRQQRQQ

LEUTX

56

A8MZ59
QANVWGAKAVRALKN

NACA4P

186

Q9BZK3
AKQKRNEQLKRWIGS

PPP1R12A

6

O14974